Chunk #13 — METHODS — QUANTITATIVE TRAIT

Source

A comparison of approaches to account for uncertainty in analysis of imputed genotypes.

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We performed the above trait simulations for 83,327 SNPs in turn for the following genetic models: additive (d = 0); partially dominant (d = (1/2)a); dominant (d = a); and over-dominant (d = (6/5)a), corresponding to a value for the heterozygote that is 10% greater than the difference between the two homozygotes.