Supplementary Table 1 shows the allele frequencies of the 75 known SNPs and one novel SNP from our SNP discovery project, in the EA and AA samples; selected SNPs, including those most associated with nicotine dependence in each sample, are in Table 1. Sixty-three SNPs show significant allele frequency differences between EAs and AAs. Nevertheless, for most SNPs the minor allele is the same in both populations; notable exceptions are rs578776 and rs3743078, which are known to be associated with nicotine dependence in European-Americans.
