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Chunk #37 — Results — Risk Prediction by ERS and its Associations with Lipid Outcomes

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Environmental risk score as a new tool to examine multi-pollutants in epidemiologic research: an example from the NHANES study using serum lipid levels.
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Figure 2 shows ORs of having adverse levels of HDL and LDL for individual pollutants that compose the ERS. Three out of the 9 pollutants (antimony, mono-benzyl phthalate, mono-(3-carboxylpropyl) phthalate) had significant positive associations with the odds of HDL, the rest except for blood lead had weak non-significant positive associations and blood lead had a weak non-significant inverse association. One of the 5 pollutants (blood lead) had a significant positive association with the odds of LDL and the rest had weak non-significant associations. In particular, the effect sizes of ERS’s in relation to LDL were larger than any of the effect sizes of individual pollutants. Here we present ORs of HDL and LDL because their ERS’s comprise the smaller number of pollutants (9 and 5 pollutants each). The plots for total cholesterol and triglycerides are shown in Figure S3.