We evaluated the heterogeneity for the interaction terms in all the previous analyses. Supplemental Table S4 lists the I2 and Q heterogeneity statistics along with the p-value for the Q statistic for all the primary and secondary meta-analyses in the subsequent tables, demonstrating that there is generally little evidence for heterogeneity in these analyses. In particular, secondary analyses refining the diagnostic criteria and the study design did not substantially decrease the heterogeneity.
