All study files were checked for quality using the software EasyQC53 that was adapted to the format from RVTESTS (versions listed in Supplementary Table 2)54. The checks performed included allele frequency differences with ancestry-specific reference panels, total number of markers, total number of markers not present in the reference panels, imputation quality, genomic inflation factor and trait transformation. We excluded two studies that did not pass our quality checks in the data.