(2,104 in Bordeaux, 4,931 in Dijon and 2,259 in Montpellier). At 8 years of follow up, 664 individuals suffered from AD with 167 prevalent and 497 incident cases. The other individuals were considered as controls. 9863 DNA samples that passed DNA quality control were genotyped with Illumina Human 610-Quad BeadChips. Following quality control procedures, a final sample size of 5,803 3C individuals (387 AD cases and 5,416 controls, cohort dataset) and 2,298 non-3C individuals (1,420 AD cases and 878 controls, case-control dataset) was included in this study.
