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Chunk #28 — Discussion

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Clinical, genomic, and neurophysiological correlates of lifetime suicide attempts among individuals with alcohol dependence.
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When we examined risk factors in aggregate, participants with AD in COGA had elevated levels of suicidal ideation, other substance use disorders, and trauma exposure compared to the general population [2, 71]. However, among those who met criteria for AD and reported suicide attempts had even greater levels of all types of traumas (sexual, assaultive, and non-assaultive), other substance use disorders, suicidal ideation, and comorbid psychiatric conditions (PTSD and major depressive disorder) relative to those who had not attempted suicide. These results confirm that those with AD who report a lifetime suicide attempt are clinically high-risk group. Future work should utilize prospective information to determine whether these individuals have similar trajectories of psychiatric problems across time.