The most commonly used SRE score is the value for the approximate first five times of drinking, the SRE-5, that potentially reflects alcohol sensitivity observed before the development of repetitive heavier drinking that might contribute to intersession tolerance (Schuckit, 2018). Less often mentioned in the literature is the more broad-based SRE Total (SRE-T) score that is based on the average drinks needed for up to four effects across all three timeframes (first five times, period of heaviest drinking, and recent three months), an approach that potentially reflects both sensitivity and the development of tolerance related to repeated drinking (e.g., Lai et al., submitted; Schuckit, 2018). Using the SRE, a higher number of drinks required for effects indicates a lower LR per drink.
