this case, the effects on AD liability are a consequence of the effects on conduct phenotypes in adolescents, and there are data that support this model (Cho et al., 2014). A second possibility is that there may be shared or distinct effects of SWI/SNF on nervous system function that are manifested in youth as a predisposition to conduct disorders and are independently revealed in adults as an increased liability to develop AD. Importantly, these models are not mutually exclusive, and in the complex landscape of genetic effects on these human behavioral phenotypes, both mechanisms may be working simultaneously.
