Descriptive statistics of the 9230 individuals in the CATSS cohort (5551 women [60.1%] and 3679 men [39.9%]) are presented in eTable 4 in the Supplement. Obsessive-compulsive symptoms were associated with increased symptoms of alcohol and drug dependence (Table 2). Among people who reported alcohol and drug use, a 1-SD increase in obsessive-compulsive symptoms was associated with a 0.2-SD increase in concurrent dependence symptoms (for alcohol use [n = 9219], β = 0.18 [95% CI, 0.16-0.20]; for drug use [n = 749], β = 0.19 [95% CI, 0.11-0.27]). Similar associations were observed in the longitudinal analyses (for alcohol use [n = 3381], β = 0.10 [95% CI, 0.06-0.14]; for drug use [n = 452], β = 0.15 [95% CI, 0.04-0.25]).
