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Chunk #20 — RESULTS — Effects of 5-HTTLPR and Stressors on the CES-D Score

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The serotonin transporter polymorphism (5-HTTLPR): allelic variation and links with depressive symptoms.
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The effect of trauma on the CES-D score is greater for the S/L than the S/XL genotype; the difference between these coefficients is marginally significant in Model 1 (p~0.09) but not Model 3. With only 24 respondents with L/XL genotype, we do not have sufficient statistical power to distinguish between L/L and L/XL. However, we estimated additional models (not shown) similar to those in Table 3, but excluding persons with L/XL genotype. The magnitude of the coefficient for the interaction between trauma and L/L remains similar but owing to the loss of statistical power is reduced to marginal significance (p~0.09).