Gene-environment interaction analysis of serotonin system markers with adolescent depression.
paper
Cited
Public
Unavailable
- Authors
- Eley, T C; Sugden, K; Corsico, A; Gregory, A M; Sham, P; McGuffin, P; Plomin, R; Craig, I W
- Year
- 2004
- Journal
- Molecular psychiatry
- PMID
- 15241435
- DOI
- 10.1038/sj.mp.4001546
We report analyses from a study of gene-environment interaction in adolescent depression. The sample was selected from 1990 adolescents aged 10-20 years: those with depression symptoms in the top or bottom 15% were identified and divided into high or low environmental risk groups. DNA was obtained from 377 adolescents, representing the four quadrants of high or low depression and high or low environmental risk. Markers within, or close to, each of the serotonergic genes 5HTT, HTR2A, HTR2C, MAOA (monoamine oxidase type A) and tryptophan hydroxylase (TPH) were genotyped. Environmental risk group was a nonsignificant predictor and sex was a significant predictor of the depression group. HTR2A and TPH significantly predicted the depression group, independent of the effects of sex, environmental risk group and their interaction. In addition, there was a trend for an effect of 5HTTLPR, which was significant in female subjects. Furthermore, there was a significant genotype-environmental risk interaction for 5HTTLPR in female subjects only, with the effect being in the same direction as another recent study, reaffirming that an important source of genetic heterogeneity is exposure to environmental risk.
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|---|---|---|---|---|
| Depression in Adolescence: Relevance of Serotonin Receptor Polymorphisms. | Gizzi G et al. | β | 2025 | β |
| Independent, Multiplicative, and Cumulative Effects of Recent Stressful Life Events and Adverse Childhood Events on Depressive Symptoms among College Students: Moderation by the HPA-axis Multilocus Genetic Variation. | Yang Y et al. | β | 2025 | β |
| Duloxetine improves chronic orofacial pain and comorbid depressive symptoms in association with reduction of serotonin transporter protein through upregulation of ubiquitinated serotonin transporter protein. | Nakamura M et al. | β | 2024 | β |
| Peer popularity and self-discipline as protective factors against depressive symptoms in Chinese adolescents: Do boys and girls benefit equally? | Zhu N et al. | β | 2024 | β |
| Pharmacogenetics of selective serotonin reuptake inhibitors (SSRI): A serotonin reuptake transporter (SERT)-based approach. | Sreeja V et al. | β | 2024 | β |
| The role of environmental sensitivity in the mental health of Syrian refugee children: a multi-level analysis. | May AK et al. | β | 2024 | β |
| Chronic mild stress induces differential depression-like symptoms and c-Fos and 5HT1A protein levels in high-anxiety female Long Evans rats. | Calhoun CA et al. | β | 2023 | β |
| Gender differences in the association of polygenic risk and divergent depression trajectories from mid to late life: a national longitudinal study. | Chen P et al. | β | 2023 | β |
| The longitudinal predictive effect of self-reported frequency of premenstrual syndrome on depression: Findings from the Australian Longitudinal Study on Women's Health. | Hou L et al. | β | 2023 | β |
| Association between sedentary behavior and depression among South Korean adolescents. | Kim J et al. | β | 2022 | β |
| Three phases of Gene Γ Environment interaction research: Theoretical assumptions underlying gene selection. | Zhang X et al. | β | 2022 | β |
| Time moderates the interplay between 5-HTTLPR and stress on depression risk: gene x environment interaction as a dynamic process. | Delli Colli C et al. | β | 2022 | β |
| Attenuated dopamine signaling after aversive learning is restored by ketamine to rescue escape actions. | Wu M et al. | β | 2021 | β |
| Baseline cell proliferation rates and response to UV differ in lymphoblastoid cell lines derived from healthy individuals of extreme constitution types. | Chakraborty S et al. | β | 2021 | β |
| Developmental disabilities across the world: A scientometric review from 1936 to 2020. | Carollo A et al. | β | 2021 | β |
| Influence of <i>FKBP5</i> Variants and Childhood Trauma on Brain Volume in Non-clinical Individuals. | Kwon A et al. | β | 2021 | β |
| Monoaminergic Multilocus Genetic Variants Interact with Stressful Life Events in Predicting Changes in Adolescent Anxiety Symptoms: A One-year Longitudinal Study. | Cao C et al. | β | 2021 | β |
| Rhythms, Reward, and Blues: Consequences of Circadian Photoperiod on Affective and Reward Circuit Function. | Siemann JK et al. | β | 2021 | β |
| Teenagers and Precision Psychiatry: A Window of Opportunity. | Sabatello M et al. | β | 2021 | β |
| The peril and promise of sensitivity in eating disorders. | Sim L et al. | β | 2021 | β |
| Tuning the activity of known drugs via the introduction of halogen atoms, a case study of SERT ligands - Fluoxetine and fluvoxamine. | StaroΕ J et al. | β | 2021 | β |
| Differential Susceptibility to Parenting in Adolescent Girls: Moderation by Neural Sensitivity to Social Cues. | Rudolph KD et al. | β | 2020 | β |
| Gender Differences in Depression: Evidence From Genetics. | Zhao L et al. | β | 2020 | β |
| Involvement of protein kinase C beta1-serotonin transporter system dysfunction in emotional behaviors in stressed mice. | Ito T et al. | β | 2020 | β |
| Photoperiodic effects on monoamine signaling and gene expression throughout development in the serotonin and dopamine systems. | Siemann JK et al. | β | 2020 | β |
| Rare variants in SLC6A4 cause susceptibility to major depressive disorder with suicidal ideation in Han Chinese adolescents and young adults. | Ran L et al. | β | 2020 | β |
| Reciprocal links between anxiety sensitivity and obsessive-compulsive symptoms in youth: a longitudinal twin study. | Krebs G et al. | β | 2020 | β |
| The relationships among MAOA, COMT Val158Met, and 5-HTTLPR polymorphisms, newborn stress reactivity, and infant temperament. | Bajgarova Z et al. | β | 2020 | β |
| Constitutive Serotonin Transporter Reduction Resembles Maternal Separation with Regard to Stress-Related Gene Expression. | Comasco E et al. | β | 2019 | β |
| <i>CACNA1C rs1006737</i>, Threatening Life Events, and Gene-Environment Interaction Predict Major Depressive Disorder. | Zhao M et al. | β | 2019 | β |
| <i>In vivo</i> Hippocampal Serotonin Dynamics in Male and Female Mice: Determining Effects of Acute Escitalopram Using Fast Scan Cyclic Voltammetry. | Saylor RA et al. | β | 2019 | β |
| Interactive effects of genetic polymorphisms and childhood adversity on brain morphologic changes in depression. | Kim YK et al. | β | 2019 | β |
| Polygenic differential susceptibility to prenatal adversity. | Belsky J et al. | β | 2019 | β |
| Risk and protective effects of serotonin and BDNF genes on stress-related adult psychiatric symptoms. | Nestor PG et al. | β | 2019 | β |
| Serotonergic system, cognition, and BPSD in Alzheimer's disease. | Chakraborty S et al. | β | 2019 | β |
| BDNF Val66Met polymorphism, life stress and depression: A meta-analysis of gene-environment interaction. | Zhao M et al. | β | 2018 | β |
| Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression. | Culverhouse RC et al. | β | 2018 | β |
| Effect of behavioral inhibition system and childhood emotional neglect on serotonergic activity, negative affect, and rejection sensitivity in non-clinical adults. | Jin MJ et al. | β | 2018 | β |
| Factors associated with depression among homeless mothers. Results of the ENFAMS survey. | Roze M et al. | β | 2018 | β |
| Gene-environment interaction and psychiatric disorders: Review and future directions. | Assary E et al. | β | 2018 | β |
| Gene Γ Environment Interaction in Developmental Disorders: Where Do We Stand and What's Next? | Esposito G et al. | β | 2018 | β |
| Gene-environment interactions between stress and 5-HTTLPR in depression: A meta-analytic update. | Bleys D et al. | β | 2018 | β |
| Glucocorticoid Receptor Genetic Variants and Response to Fluoxetine in Major Depressive Disorder. | Nouraei H et al. | β | 2018 | β |
| Maternal anxiety and depressive disorders prior to, during and after pregnancy and infant interaction behaviors during the Face-to-Face Still Face Paradigm at 4β―months postpartum: A prospective-longitudinal study. | Asselmann E et al. | β | 2018 | β |
| Serotonin neuron development: shaping molecular and structural identities. | Deneris E et al. | β | 2018 | β |
| A Set-Based Mixed Effect Model for Gene-Environment Interaction and Its Application to Neuroimaging Phenotypes. | Wang C et al. | β | 2017 | β |
| Assessment of Pain Sensitivity in Patients With Chronic Low Back Pain and Association With HTR2A Gene Polymorphism. | Yildiz SH et al. | β | 2017 | β |
| Behavioral Genetics in Criminal and Civil Courts. | Sabatello M et al. | β | 2017 | β |
| Consequences of early adverse rearing experience(EARE) on development: insights from non-human primate studies. | Zhang B | β | 2017 | β |
| Cumulative prenatal exposure to adversity reveals associations with a broad range of neurodevelopmental outcomes that are moderated by a novel, biologically informed polygenetic score based on the serotonin transporter solute carrier family C6, member 4 (SLC6A4) gene expression. | Silveira PP et al. | β | 2017 | β |
| Developmental changes in serotonin signaling: Implications for early brain function, behavior and adaptation. | Brummelte S et al. | β | 2017 | β |
| Epigenetic and Neural Circuitry Landscape of Psychotherapeutic Interventions. | Miller CWT | β | 2017 | β |
| Fluoxetine effects on molecular, cellular and behavioral endophenotypes of depression are driven by the living environment. | Alboni S et al. | β | 2017 | β |
| Gene Γ Environment Interactions: From Molecular Mechanisms to Behavior. | Halldorsdottir T et al. | β | 2017 | β |
| Immune System Activation and Depression: Roles of Serotonin in the Central Nervous System and Periphery. | Robson MJ et al. | β | 2017 | β |
| Letter to the Editor: Bias in the measurement of bias. Letter regarding 'Citation bias and selective focus on positive findings in the literature on the serotonin transporter gene (5-HTTLPR), life stress and depression'. | Vrshek-Schallhorn S et al. | β | 2017 | β |
| Letter to the Editor: Moving science forward by increasing awareness of reporting and citation biases: a reply to Vrshek-Schallhorn et al. (2016). | de Vries YA et al. | β | 2017 | β |
| Parenting and adolescents' psychological adjustment: Longitudinal moderation by adolescents' genetic sensitivity. | Stocker CM et al. | β | 2017 | β |
| Prenatal exposure to organophosphorus pesticides and childhood neurodevelopmental phenotypes. | Furlong MA et al. | β | 2017 | β |
| Relationships Between Self-Reported and Observed Parenting Behaviour, Adolescent Disordered Eating Attitudes and Behaviours, and the 5-HTTLPR Polymorphism: Data From the Australian Temperament Project. | Rozenblat V et al. | β | 2017 | β |
| Sex differences modulating serotonergic polymorphisms implicated in the mechanistic pathways of risk for depression and related disorders. | Perry LM et al. | β | 2017 | β |
| 5-HTTLPR and gender differences in affective disorders: A systematic review. | Gressier F et al. | β | 2016 | β |
| Depression, Stressful Life Events, and the Impact of Variation in the Serotonin Transporter: Findings from the National Longitudinal Study of Adolescent to Adult Health (Add Health). | Haberstick BC et al. | β | 2016 | β |
| Differential sensitivity to the environment: contribution of cognitive biases and genes to psychological wellbeing. | Fox E et al. | β | 2016 | β |
| Early origins of mental disorder - risk factors in the perinatal and infant period. | Newman L et al. | β | 2016 | β |
| FKBP5 polymorphisms moderate the influence of adverse life events on the risk of anxiety and depressive disorders in preschool children. | Scheuer S et al. | β | 2016 | β |
| Generalized Hierarchical Sparse Model for Arbitrary-Order Interactive Antigenic Sites Identification in Flu Virus Data. | Han L et al. | β | 2016 | β |
| Non-replication of the association between 5HTTLPR and response to psychological therapy for child anxiety disorders. | Lester KJ et al. | β | 2016 | β |
| Puberty, Socioeconomic Status, and Depression in Girls: Evidence for Gene Γ Environment Interactions. | Mendle J et al. | β | 2016 | β |
| Revisiting the Serotonin Hypothesis: Implications for Major Depressive Disorders. | Fakhoury M | β | 2016 | β |
| Serotonin neurons in a dish. | Gaspar P et al. | β | 2016 | β |
| Serotonin signaling modulates the effects of familial risk for depression on cortical thickness. | Bansal R et al. | β | 2016 | β |
| The ubiquitination of serotonin transporter in lymphoblasts derived from fluvoxamine-resistant depression patients. | Mouri A et al. | β | 2016 | β |
| Traumatic and Adverse Attachment Childhood Experiences are not Characteristic of OCD but of Depression in Adolescents. | Ivarsson T et al. | β | 2016 | β |
| Variation in serotonin transporter linked polymorphic region (5-HTTLPR) short/long genotype modulates resting frontal electroencephalography asymmetries in children. | Christou AI et al. | β | 2016 | β |
| Allelic variation at 5-HTTLPR is associated with brain morphology in a Chinese population. | Liu J et al. | β | 2015 | β |
| Association of Anxiety Symptoms in Offspring of Bipolar Parents with Serotonin Transporter-Linked Polymorphic Region (5-HTTLPR) Genotype. | Park MH et al. | β | 2015 | β |
| Association study of monoamine oxidase-A gene promoter polymorphism (MAOA-uVNTR) with self-reported anxiety and other psychopathological symptoms in a community sample of early adolescents. | Voltas N et al. | β | 2015 | β |
| Benefits of adversity?! How life history affects the behavioral profile of mice varying in serotonin transporter genotype. | Bodden C et al. | β | 2015 | β |
| Biological determinants of depression following bereavement. | Assareh AA et al. | β | 2015 | β |
| Depression from childhood into late adolescence: Influence of gender, development, genetic susceptibility, and peer stress. | Hankin BL et al. | β | 2015 | β |
| Gender differences in association between serotonin transporter gene polymorphism and resting-state EEG activity. | Volf NV et al. | β | 2015 | β |
| Genetic vulnerability, timing of short-term stress and mood regulation: A rodent diffusion tensor imaging study. | Zalsman G et al. | β | 2015 | β |
| Influence of Serotonin Transporter Gene Polymorphisms and Adverse Life Events on Depressive Symptoms in the Elderly: A Population-Based Study. | Davin A et al. | β | 2015 | β |
| Serotonin transporter polymorphism (<i>5HTTLPR</i>), severe childhood abuse and depressive symptom trajectories in adulthood. | Nguyen TB et al. | β | 2015 | β |
| The Dopamine D2 Receptor Polymorphism (DRD2 TaqIA) Interacts with Maternal Parenting in Predicting Early Adolescent Depressive Symptoms: Evidence of Differential Susceptibility and Age Differences. | Zhang W et al. | β | 2015 | β |
| The Involvement of Genes in Adolescent Depression: A Systematic Review. | Xia L et al. | β | 2015 | β |
| Variations in central serotonergic activity - relevance of the 5-HTTLPR, life events and their interaction. | Wielpuetz C et al. | β | 2015 | β |
| 5-HTTLPR, anxiety and gender interaction moderates right amygdala volume in healthy subjects. | Cerasa A et al. | β | 2014 | β |
| 5-Hydroxy tryptamine transporter (5HTT) gene promoter region polymorphism in anxiety and depressive disorders. | Mushtaq R et al. | β | 2014 | β |
| An update on the interaction between the serotonin transporter promoter variant (5-HTTLPR), stress and depression, plus an exploration of non-confirming findings. | Sharpley CF et al. | β | 2014 | β |
| A Preliminary Examination of the Relationship Between the <i>5-HTTLPR</i> and Childhood Emotional Abuse on Depressive Symptoms in 10-12-Year-Old Youth. | Banducci AN et al. | β | 2014 | β |
| Association of HTR2A T102C and A-1438G polymorphisms with susceptibility to major depressive disorder: a meta-analysis. | Zhao X et al. | β | 2014 | β |
| Concurrent trajectories of change in adolescent and maternal depressive symptoms in the TORDIA study. | Perloe A et al. | β | 2014 | β |
| Genetic susceptibility to family environment: BDNF Val66met and 5-HTTLPR influence depressive symptoms. | Dalton ED et al. | β | 2014 | β |
| Immune changes and neurotransmitters: possible interactions in depression? | Sperner-Unterweger B et al. | β | 2014 | β |
| Interaction between stress and the BDNF Val66Met polymorphism in depression: a systematic review and meta-analysis. | Hosang GM et al. | β | 2014 | β |
| Lack of association between the 5-HTTLPR and positive screening for mental disorders among children exposed to urban violence and maltreatment. | Cividanes GC et al. | β | 2014 | β |
| Linking Childhood Maltreatment with Girls' Internalizing Symptoms: Early Puberty as a Tipping Point. | Mendle J et al. | β | 2014 | β |
| Negative emotionality mediates the association of 5-HTTLPR genotype and depression in children with and without ADHD. | Li JJ et al. | β | 2014 | β |
| Plasma fluoxetine concentrations and clinical improvement in an adolescent sample diagnosed with major depressive disorder, obsessive-compulsive disorder, or generalized anxiety disorder. | BlΓ‘zquez A et al. | β | 2014 | β |
| Reconceptualizing sex, brain and psychopathology: interaction, interaction, interaction. | Joel D et al. | β | 2014 | β |
| Serotonin receptor gene (5HT-2A) polymorphism is associated with provoked vestibulodynia and comorbid symptoms of pain. | Heddini U et al. | β | 2014 | β |
| Serotonin transporter [corrected] methylation and response to cognitive behaviour therapy in children with anxiety disorders. | Roberts S et al. | β | 2014 | β |
| Serotonin transporter gene Γ environment and risk of depression in community-treated epilepsy. | Lacey CJ et al. | β | 2014 | β |
| Serotonin transporter polymorphisms (5-HTTLPR) in emotion processing: implications from current neurobiology. | Jonassen R et al. | β | 2014 | β |
| Social subordination stress and serotonin transporter polymorphisms: associations with brain white matter tract integrity and behavior in juvenile female macaques. | Howell BR et al. | β | 2014 | β |
| The evolutionary history of SLC6A4 and the role of plasticity in Macaca. | Shattuck MR et al. | β | 2014 | β |
| Who is predisposed to insomnia: a review of familial aggregation, stress-reactivity, personality and coping style. | Harvey CJ et al. | β | 2014 | β |
| 5-HTTLPR X stress in adolescent depression: moderation by MAOA and gender. | Priess-Groben HA et al. | β | 2013 | β |
| Antidepressant treatment outcome depends on the quality of the living environment: a pre-clinical investigation in mice. | Branchi I et al. | β | 2013 | β |
| Association of serotonin-1A and -2A receptor promoter polymorphisms with depressive symptoms, functional recovery, and pain in patients 6 months after lumbar disc surgery. | Lebe M et al. | β | 2013 | β |
| Children's risk and resilience following a natural disaster: genetic vulnerability, posttraumatic stress, and depression. | La Greca AM et al. | β | 2013 | β |
| Depression as an evolutionary strategy for defense against infection. | Anders S et al. | β | 2013 | β |
| Differential susceptibility in longitudinal models of gene-environment interaction for adolescent depression. | Li JJ et al. | β | 2013 | β |
| Effect of gene, environment and maternal depressive symptoms on pre-adolescence behavior problems - a longitudinal study. | Agnafors S et al. | β | 2013 | β |
| Environmental and pharmacological modulations of cellular plasticity: role in the pathophysiology and treatment of depression. | Ota KT et al. | β | 2013 | β |
| Gene Γ environment effects of serotonin transporter, dopamine receptor D4, and monoamine oxidase A genes with contextual and parenting risk factors on symptoms of oppositional defiant disorder, anxiety, and depression in a community sample of 4-year-old children. | Lavigne JV et al. | β | 2013 | β |
| Gene environment interaction studies in depression and suicidal behavior: An update. | Mandelli L et al. | β | 2013 | β |
| Implications of the use of genetic tests in psychiatry, with a focus on major depressive disorder: a review. | Wilde A et al. | β | 2013 | β |
| Interaction between a serotonin transporter gene promoter region polymorphism and stress predicts depressive symptoms in Chinese adolescents: a multi-wave longitudinal study. | Ming QS et al. | β | 2013 | β |
| Interaction between specific forms of childhood maltreatment and the serotonin transporter gene (5-HTT) in recurrent depressive disorder. | Fisher HL et al. | β | 2013 | β |
| Peripuberty stress leads to abnormal aggression, altered amygdala and orbitofrontal reactivity and increased prefrontal MAOA gene expression. | MΓ‘rquez C et al. | β | 2013 | β |
| Relational security moderates the effect of serotonin transporter gene polymorphism (5-HTTLPR) on stress generation and depression among adolescents. | Starr LR et al. | β | 2013 | β |
| Serotonergic genes (5-HTT and HTR1A) and separation life events: gene-by-environment interaction for panic disorder. | Choe AY et al. | β | 2013 | β |
| Serotonin transporter length polymorphism, childhood maltreatment, and chronic depression: a specific gene-environment interaction. | Brown GW et al. | β | 2013 | β |
| Serotonin Transporter Polymorphism (5-HTTLPR) and Citalopram Effectiveness in Iranian Patients with Major Depressive Disorder. | Sahraian S et al. | β | 2013 | β |
| The current state of play on the molecular genetics of depression. | Cohen-Woods S et al. | β | 2013 | β |
| The Depression Impairment Scale for Parents (DISP): a new scale for the measurement of impairment in depressed parents. | Lewis K et al. | β | 2013 | β |
| The interaction between child maltreatment, adult stressful life events and the 5-HTTLPR in major depression. | Power RA et al. | β | 2013 | β |
| Vulnerability to depression: a moderated mediation model of the roles of child maltreatment, peer victimization, and serotonin transporter linked polymorphic region genetic variation among children from low socioeconomic status backgrounds. | Banny AM et al. | β | 2013 | β |
| 5-HTTLPR S-allele: a genetic plasticity factor regarding the effects of life events on personality? | Kuepper Y et al. | β | 2012 | β |
| An imaging genetics approach to understanding social influence. | Falk EB et al. | β | 2012 | β |
| Anxiety, Depression, and Somatic Distress: Developing a Transdiagnostic Internalizing Toolbox for Pediatric Practice. | Weersing VR et al. | β | 2012 | β |
| Anxiety sensitivity in adolescence and young adulthood: the role of stressful life events, 5HTTLPR and their interaction. | Zavos HM et al. | β | 2012 | β |
| Biological indicators of suicide risk in youth with mood disorders: what do we know so far? | Lewitzka U et al. | β | 2012 | β |
| Children of mothers with borderline personality disorder: identifying parenting behaviors as potential targets for intervention. | Stepp SD et al. | β | 2012 | β |
| Coaction of stress and serotonin transporter genotype in predicting aggression at the transition to adulthood. | Conway CC et al. | β | 2012 | β |
| Determining gene moderation of environmental risk factors for a mental disorder: a "perfect storm" of methodological problems. | Kraemer HC | β | 2012 | β |
| Differential susceptibility in spillover between interparental conflict and maternal parenting practices: evidence for OXTR and 5-HTT genes. | Sturge-Apple ML et al. | β | 2012 | β |
| Emerging risk factors for postpartum depression: serotonin transporter genotype and omega-3 fatty acid status. | Shapiro GD et al. | β | 2012 | β |
| Fetal serotonin signaling: setting pathways for early childhood development and behavior. | Oberlander TF | β | 2012 | β |
| Fluoxetine pharmacogenetics in child and adult populations. | Blazquez A et al. | β | 2012 | β |
| Future directions in vulnerability to depression among youth: integrating risk factors and processes across multiple levels of analysis. | Hankin BL | β | 2012 | β |
| Influence of threat and serotonin transporter genotype on interference effects. | Jasinska AJ et al. | β | 2012 | β |
| Interaction between serotonin transporter polymorphism (5-HTTLPR) and stressful life events in adolescents' trajectories of anxious/depressed symptoms. | Petersen IT et al. | β | 2012 | β |
| Interaction of serotonin transporter linked polymorphic region and childhood neglect on criminal behavior and substance use for males and females. | Vaske J et al. | β | 2012 | β |
| Macrophage migration inhibitory factor mediates the antidepressant actions of voluntary exercise. | Moon HY et al. | β | 2012 | β |
| Maternal depression and child and adolescent depression symptoms: an exploratory test for moderation by CRHR1, FKBP5 and NR3C1 gene variants. | Lewis G et al. | β | 2012 | β |
| Mouse models of the 5-HTTLPR Γ stress risk factor for depression. | Carola V et al. | β | 2012 | β |
| Multigene interactions and the prediction of depression in the Wisconsin Longitudinal Study. | Roetker NS et al. | β | 2012 | β |
| Platelets and depression in cardiovascular disease: A brief review of the current literature. | Williams MS | β | 2012 | β |
| School connectedness, peer attachment, and self-esteem as predictors of adolescent depression. | Millings A et al. | β | 2012 | β |
| Serotonin transporter genotype 5HTTLPR as a marker of differential susceptibility? A meta-analysis of child and adolescent gene-by-environment studies. | van Ijzendoorn MH et al. | β | 2012 | β |
| Sex modulates the interactive effect of the serotonin transporter gene polymorphism and childhood adversity on hippocampal volume. | Everaerd D et al. | β | 2012 | β |
| Stressful life events and the serotonin transporter gene (5-HTT) in recurrent clinical depression. | Fisher HL et al. | β | 2012 | β |
| The 5-HTTLPR polymorphism moderates the effect of stressful life events on drinking behavior in college students of African descent. | Kranzler HR et al. | β | 2012 | β |
| The serotonin transporter gene and functional and pathological adaptation to environmental variation across the life span. | Homberg JR et al. | β | 2012 | β |
| The SLC6A4 VNTR genotype determines transcription factor binding and epigenetic variation of this gene in response to cocaine in vitro. | Vasiliou SA et al. | β | 2012 | β |
| Treatment resistance and psychodynamic psychiatry: concepts psychiatry needs from psychoanalysis. | Plakun E | β | 2012 | β |
| Why do anxious children become depressed teenagers? The role of social evaluative threat and reward processing. | Silk JS et al. | β | 2012 | β |
| 5-HTTLPR genotype and associations with intoxication and intention to drive: results from a field study of bar patrons. | Thombs DL et al. | β | 2011 | β |
| Affective and neuroendocrine stress reactivity to an academic examination: influence of the 5-HTTLPR genotype and trait neuroticism. | Verschoor E et al. | β | 2011 | β |
| A polymorphism in the serotonin transporter gene moderates cardiovascular reactivity to psychosocial stress. | Way BM et al. | β | 2011 | β |
| A protective genetic variant for adverse environments? The role of childhood traumas and serotonin transporter gene on resilience and depressive severity in a high-risk population. | Carli V et al. | β | 2011 | β |
| Association between a serotonin transporter promoter polymorphism (5HTTLPR) and personality disorder traits in a community sample. | Blom RM et al. | β | 2011 | β |
| Association of HTR2A polymorphisms with chronic widespread pain and the extent of musculoskeletal pain: results from two population-based cohorts. | Nicholl BI et al. | β | 2011 | β |
| Association of polymorphisms of the serotonergic pathways with clinical traits of impulsive-aggression and suicidality in adolescents: a multi-center study. | Zalsman G et al. | β | 2011 | β |
| A systematic evaluation and validation of subtypes of adolescent alcohol use motives: genetic and environmental contributions. | Mackie CJ et al. | β | 2011 | β |
| A topographical map of the causal network of mechanisms underlying the relationship between major depressive disorder and coronary heart disease. | Stapelberg NJ et al. | β | 2011 | β |
| Building conditions, 5-HTTLPR genotype, and depressive symptoms in adolescent males and females. | Uddin M et al. | β | 2011 | β |
| Chronic family stress interacts with 5-HTTLPR to predict prospective depressive symptoms among youth. | Jenness JL et al. | β | 2011 | β |
| Community interest in predictive genetic testing for susceptibility to major depressive disorder in a large national sample. | Wilde A et al. | β | 2011 | β |
| Dependent negative life events and sleep quality: an examination of gene-environment interplay. | Barclay NL et al. | β | 2011 | β |
| Differential susceptibility in youth: evidence that 5-HTTLPR x positive parenting is associated with positive affect 'for better and worse'. | Hankin BL et al. | β | 2011 | β |
| Differential susceptibility to the environment: an evolutionary--neurodevelopmental theory. | Ellis BJ et al. | β | 2011 | β |
| Droplets of black bile? Development of vulnerability and resilience to depression in young age. | Harro J et al. | β | 2011 | β |
| Early adversity and adult health outcomes. | Taylor SE et al. | β | 2011 | β |
| Four potential criteria for deciding when to use antidepressants or psychotherapy for unipolar depression: a literature review. | Sharpley CF et al. | β | 2011 | β |
| Gene-environment interactions: early life stress and risk for depressive and anxiety disorders. | Nugent NR et al. | β | 2011 | β |
| Influence of birth weight on internalizing traits modulated by serotonergic genes. | Broekman BF et al. | β | 2011 | β |
| Interaction of 5-HTTLPR and idiographic stressors predicts prospective depressive symptoms specifically among youth in a multiwave design. | Hankin BL et al. | β | 2011 | β |
| Interaction of serotonin transporter gene-linked polymorphic region and stressful life events predicts cortisol stress response. | Mueller A et al. | β | 2011 | β |
| Life stressors and 5-HTTLPR interaction in relation to midpregnancy depressive symptoms among African-American women. | Scheid JM et al. | β | 2011 | β |
| Parental depressive feelings, parental support, and the serotonin transporter gene as predictors of adolescent depressive feelings: a latent growth curve analysis. | van Roekel E et al. | β | 2011 | β |
| Perceived discrimination, serotonin transporter linked polymorphic region status, and the development of conduct problems. | Brody GH et al. | β | 2011 | β |
| Research review: gene-environment interaction research in youth depression - a systematic review with recommendations for future research. | Dunn EC et al. | β | 2011 | β |
| Sensitivity to the depressogenic effect of stress and HPA-axis reactivity in adolescence: a review of gender differences. | Oldehinkel AJ et al. | β | 2011 | β |
| Serotonin, depression, and cardiovascular disease: sex-specific issues. | Steiner M | β | 2011 | β |
| Serotonin-related gene pathways associated with undifferentiated somatoform disorder. | Koh KB et al. | β | 2011 | β |
| Serotonin transporter gene polymorphism and psychiatric disorders: is there a link? | Margoob MA et al. | β | 2011 | β |
| Serotonin transporter gene variants and prediction of stress-induced risk for psychological distress. | Stefanis NC et al. | β | 2011 | β |
| Sleep quality and diurnal preference in a sample of young adults: associations with 5HTTLPR, PER3, and CLOCK 3111. | Barclay NL et al. | β | 2011 | β |
| Structure and etiology of co-occurring internalizing and externalizing disorders in adolescents. | Cosgrove VE et al. | β | 2011 | β |
| The double edged sword of neural plasticity: increasing serotonin levels leads to both greater vulnerability to depression and improved capacity to recover. | Branchi I | β | 2011 | β |
| The possible contributory role of the S allele of 5-HTTLPR in the emergence of suicidality. | Gonda X et al. | β | 2011 | β |
| The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation. | Karg K et al. | β | 2011 | β |
| The truth about genetic variation in the serotonin transporter gene and response to stress and medication. | McGuffin P et al. | β | 2011 | β |
| War exposure, 5-HTTLPR genotype and lifetime risk of depression. | Artero S et al. | β | 2011 | β |
| 5HTT genotype moderates the influence of early institutional deprivation on emotional problems in adolescence: evidence from the English and Romanian Adoptee (ERA) study. | Kumsta R et al. | β | 2010 | β |
| 5-HTTLPR moderates effects of current life events on neuroticism: differential susceptibility to environmental influences. | Pluess M et al. | β | 2010 | β |
| 5-HTTLPR moderates the effect of relational peer victimization on depressive symptoms in adolescent girls. | Benjet C et al. | β | 2010 | β |
| Association between a serotonin transporter gene variant and hopelessness among men in the Heart and Soul Study. | Kangelaris KN et al. | β | 2010 | β |
| Baseline brain perfusion and the serotonin transporter promoter polymorphism. | Viviani R et al. | β | 2010 | β |
| BDNF gene polymorphism (Val66Met) predicts amygdala and anterior hippocampus responses to emotional faces in anxious and depressed adolescents. | Lau JY et al. | β | 2010 | β |
| Childhood socioeconomic status and adult health. | Cohen S et al. | β | 2010 | β |
| Child maltreatment moderates the association of MAOA with symptoms of depression and antisocial personality disorder. | Beach SR et al. | β | 2010 | β |
| Chronic and acute stress, gender, and serotonin transporter gene-environment interactions predicting depression symptoms in youth. | Hammen C et al. | β | 2010 | β |
| Current developments and controversies: does the serotonin transporter gene-linked polymorphic region (5-HTTLPR) modulate the association between stress and depression? | Wankerl M et al. | β | 2010 | β |
| Epigenetics and the biological definition of gene x environment interactions. | Meaney MJ | β | 2010 | β |
| From nature versus nurture, via nature and nurture, to gene x environment interaction in mental disorders. | Wermter AK et al. | β | 2010 | β |
| Gender differences in the genetic and environmental determinants of adolescent depression. | Uddin M et al. | β | 2010 | β |
| Gene-environment interactions and response to social intrusion in male and female rhesus macaques. | Schwandt ML et al. | β | 2010 | β |
| Genetics of childhood and adolescent depression: insights into etiological heterogeneity and challenges for future genomic research. | Rice F | β | 2010 | β |
| Interaction between serotonin 5-HT2A receptor gene and dopamine transporter (DAT1) gene polymorphisms influences personality trait of persistence in Austrian Caucasians. | Schosser A et al. | β | 2010 | β |
| Loneliness in adolescence: gene x environment interactions involving the serotonin transporter gene. | van Roekel E et al. | β | 2010 | β |
| Meta-analysis of the BDNF Val66Met polymorphism in major depressive disorder: effects of gender and ethnicity. | Verhagen M et al. | β | 2010 | β |
| Modification of depression by COMT val158met polymorphism in children exposed to early severe psychosocial deprivation. | Drury SS et al. | β | 2010 | β |
| Neurobiological adaptations to violence across development. | Mead HK et al. | β | 2010 | β |
| Person-environment interaction in the prediction of alcohol abuse and alcohol dependence in adulthood. | Hill KG et al. | β | 2010 | β |
| Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms. | Ressler KJ et al. | β | 2010 | β |
| Public interest in predictive genetic testing, including direct-to-consumer testing, for susceptibility to major depression: preliminary findings. | Wilde A et al. | β | 2010 | β |
| Serotonin pathway gene-gene and gene-environment interactions influence behavioral stress response in infant rhesus macaques. | Kinnally EL et al. | β | 2010 | β |
| Serotonin transporter gene, childhood emotional abuse and cognitive vulnerability to depression. | Antypa N et al. | β | 2010 | β |
| Social influences on health: is serotonin a critical mediator? | Way BM et al. | β | 2010 | β |
| The heritability of postpartum depression. | Corwin EJ et al. | β | 2010 | β |
| The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology. | Martin EI et al. | β | 2010 | β |
| The role of the serotonin transporter polymorphism for the endocrine stress response in newborns. | Mueller A et al. | β | 2010 | β |
| The serotonin transporter polymorphism (5-HTTLPR): allelic variation and links with depressive symptoms. | Goldman N et al. | β | 2010 | β |
| Timing is critical: gene, environment and timing interactions in genetics of suicide in children and adolescents. | Zalsman G | β | 2010 | β |
| 5-HTTLPR modulates antidepressant efficacy in depressed women. | Gressier F et al. | β | 2009 | β |
| Accumulation of trauma over time and risk for depression in a twin sample. | McCutcheon VV et al. | β | 2009 | β |
| Adolescents' mental health in Abha city, southwestern Saudi Arabia. | Mahfouz AA et al. | β | 2009 | β |
| Amygdala function and 5-HTT gene variants in adolescent anxiety and major depressive disorder. | Lau JY et al. | β | 2009 | β |
| Association of monoamine oxidase A (MAOA) polymorphisms and clinical subgroups of major depressive disorders in the Han Chinese population. | Huang SY et al. | β | 2009 | β |
| Clinical implications of genetic variation in the serotonin transporter promoter region: a review. | Luddington NS et al. | β | 2009 | β |
| Community attitudes towards mental health interventions for healthy people on the basis of genetic susceptibility. | Wilde A et al. | β | 2009 | β |
| Dopamine and serotonin systems modify environmental effects on human behavior: a review. | Keltikangas-JΓ€rvinen L et al. | β | 2009 | β |
| Dopamine and serotonin transporter genotypes moderate sensitivity to maternal expressed emotion: the case of conduct and emotional problems in attention deficit/hyperactivity disorder. | Sonuga-Barke EJ et al. | β | 2009 | β |
| Dopamine transporter gene polymorphism moderates the effects of severe deprivation on ADHD symptoms: developmental continuities in gene-environment interplay. | Stevens SE et al. | β | 2009 | β |
| Effects of stressful life events, maternal depression and 5-HTTLPR genotype on emotional symptoms in pre-adolescent children. | Araya R et al. | β | 2009 | β |
| Emotional disorders: cluster 4 of the proposed meta-structure for DSM-V and ICD-11. | Goldberg DP et al. | β | 2009 | β |
| Etiological mechanisms of post-stroke depression: a review. | Fang J et al. | β | 2009 | β |
| Family processes in the development of youth depression: translating the evidence to treatment. | Restifo K et al. | β | 2009 | β |
| From age correction to genome-wide association. | Cohen-Woods S et al. | β | 2009 | β |
| From a genetic predisposition to an interactive predisposition: rethinking the ethical implications of screening for gene-environment interactions. | Tabery J | β | 2009 | β |
| Frontal-limbic white matter pathway associations with the serotonin transporter gene promoter region (5-HTTLPR) polymorphism. | Pacheco J et al. | β | 2009 | β |
| Gene-environment interaction and suicidal behavior. | Roy A et al. | β | 2009 | β |
| Gene-environment interaction tests for dichotomous traits in trios and sibships. | Hoffmann TJ et al. | β | 2009 | β |
| Gene-environment interplay between peer rejection and depressive behavior in children. | Brendgen M et al. | β | 2009 | β |
| Genetic variation in 5HTTLPR is associated with emotional resilience. | Stein MB et al. | β | 2009 | β |
| Gene X environment interactions at the serotonin transporter locus. | MunafΓ² MR et al. | β | 2009 | β |
| Gene X environment interactions in reading disability and attention-deficit/hyperactivity disorder. | Pennington BF et al. | β | 2009 | β |
| Impact of the interaction between the 5HTTLPR polymorphism and maltreatment on adolescent depression. A population-based study. | Aslund C et al. | β | 2009 | β |
| Interaction between genetic polymorphisms and stressful life events in first episode depression. | Bukh JD et al. | β | 2009 | β |
| Interaction between the 5-HTTLPR serotonin transporter polymorphism and environmental adversity for mood and anxiety psychopathology: evidence from a high-risk community sample of young adults. | Laucht M et al. | β | 2009 | β |
| Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. | Risch N et al. | β | 2009 | β |
| Issues concerning feedback about genetic testing and risk of depression. | Wilhelm K et al. | β | 2009 | β |
| Molecular epidemiology of major depressive disorder. | Kiyohara C et al. | β | 2009 | β |
| Parental care moderates the influence of MAOA-uVNTR genotype and childhood stressors on trait impulsivity and aggression in adult women. | Kinnally EL et al. | β | 2009 | β |
| Parenting moderates a genetic vulnerability factor in longitudinal increases in youths' substance use. | Brody GH et al. | β | 2009 | β |
| Persistent versus transient depressive symptoms in relation to platelet hyperactivation: a longitudinal analysis of dementia caregivers. | Aschbacher K et al. | β | 2009 | β |
| Personality and the serotonin transporter gene: Associations in a longitudinal population-based study. | Harro J et al. | β | 2009 | β |
| Post-traumatic stress disorder: emerging concepts of pharmacotherapy. | Baker DG et al. | β | 2009 | β |
| Prevention effects moderate the association of 5-HTTLPR and youth risk behavior initiation: gene x environment hypotheses tested via a randomized prevention design. | Brody GH et al. | β | 2009 | β |
| Psychological vulnerability differences in students--carriers or not of the serotonin transporter promoter allele S: effect of adverse experiences. | Veletza S et al. | β | 2009 | β |
| Serotonin transporter gene variation and stressful life events impact processing of fear and anxiety. | Armbruster D et al. | β | 2009 | β |
| Serotonin transporter genotype, morning cortisol and subsequent depression in adolescents. | Goodyer IM et al. | β | 2009 | β |
| Smoking as a product of gene-environment interaction. | Nilsson KW et al. | β | 2009 | β |
| The combined effects of the 5-HTTLPR and 5-HTR1A genes modulates the relationship between negative life events and major depressive disorder in a Chinese population. | Zhang K et al. | β | 2009 | β |
| The genetics of depression in childhood and adolescence. | Rice F | β | 2009 | β |
| The importance of a genetic component in longitudinal birth cohorts. | Golding J | β | 2009 | β |
| The influence of family structure, the TPH2 G-703T and the 5-HTTLPR serotonergic genes upon affective problems in children aged 10-14 years. | Nobile M et al. | β | 2009 | β |
| The interaction of DRD2 and violent victimization on depression: an analysis by gender and race. | Vaske J et al. | β | 2009 | β |
| The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology. | Martin EI et al. | β | 2009 | β |
| The norepinephrine transporter gene modulates the relationship between urban/rural residency and major depressive disorder in a Chinese population. | Xu Y et al. | β | 2009 | β |
| The roles of sex and serotonin transporter levels in age- and stress-related emotionality in mice. | Joeyen-Waldorf J et al. | β | 2009 | β |
| Transcription factor AP-2 beta genotype and psychosocial adversity in relation to adolescent depressive symptomatology. | Nilsson KW et al. | β | 2009 | β |
| Unipolar depressive disorders have a common genotype. | Edvardsen J et al. | β | 2009 | β |
| Vulnerability genes or plasticity genes? | Belsky J et al. | β | 2009 | β |
| 5-HTTLPR and gender moderate changes in negative affect responses to tryptophan infusion. | Brummett BH et al. | β | 2008 | β |
| Adolescent Suicidal Behavior and Substance Use: Developmental Mechanisms. | Dawes MA et al. | β | 2008 | β |
| A functional serotonin transporter promoter gene polymorphism increases ADHD symptoms in delinquents: interaction with adverse childhood environment. | Retz W et al. | β | 2008 | β |
| Allostatic load in bipolar disorder: implications for pathophysiology and treatment. | Kapczinski F et al. | β | 2008 | β |
| Amygdala responses to emotional faces in twins discordant or concordant for the risk for anxiety and depression. | Wolfensberger SP et al. | β | 2008 | β |
| A serotonin transporter gene polymorphism (5-HTTLPR), drinking-to-cope motivation, and negative life events among college students. | Armeli S et al. | β | 2008 | β |
| Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. | Binder EB et al. | β | 2008 | β |
| Associations among central nervous system serotonergic function and neuroticism are moderated by gender. | Brummett BH et al. | β | 2008 | β |
| Association study of serotonin system genes in childhood-onset mood disorder. | Shaikh SA et al. | β | 2008 | β |
| Depression and the serotonin transporter 5-HTTLPR polymorphism: a review and a hypothesis concerning gene-environment interaction. | Brown GW et al. | β | 2008 | β |
| Depression in children. | Kapornai K et al. | β | 2008 | β |
| Depression in young people: description, assessment and evidence-based treatment. | Carr A | β | 2008 | β |
| Disentangling gene-environment correlations and interactions on adolescent depressive symptoms. | Lau JY et al. | β | 2008 | β |
| Early-emerging cognitive vulnerability to depression and the serotonin transporter promoter region polymorphism. | Hayden EP et al. | β | 2008 | β |
| Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphic region (5-HTTLPR). | Brummett BH et al. | β | 2008 | β |
| Emanuel Miller Lecture: early onset depressions--meanings, mechanisms and processes. | Goodyer IM | β | 2008 | β |
| Family history of depression is associated with younger age of onset in patients with recurrent depression. | Tozzi F et al. | β | 2008 | β |
| Finding gene-environment interactions for generalised anxiety disorder. | Gregory AM et al. | β | 2008 | β |
| Forum: Interactions between gene and environment. | Flint J et al. | β | 2008 | β |
| Gene-by-environment (serotonin transporter and childhood maltreatment) interaction for anxiety sensitivity, an intermediate phenotype for anxiety disorders. | Stein MB et al. | β | 2008 | β |
| Gene-environment interactions in depression research: genetic polymorphisms and life-stress polyprocedures. | Monroe SM et al. | β | 2008 | β |
| Gene environment interplay: nonhuman primate models in the study of resilience and vulnerability. | Bennett AJ | β | 2008 | β |
| Heterogeneity in antisocial behaviours and comorbidity with depressed mood: a behavioural genetic approach. | Rowe R et al. | β | 2008 | β |
| Identification of neurogenetic pathways of risk for psychopathology. | Fisher PM et al. | β | 2008 | β |
| Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene. | Bradley RG et al. | β | 2008 | β |
| Interaction of child and family psychopathology leading to suicidal behavior. | Zalsman G et al. | β | 2008 | β |
| Modern approaches to conceptualizing and measuring human life stress. | Monroe SM | β | 2008 | β |
| Neither single-marker nor haplotype analyses support an association between monoamine oxidase A gene and bipolar disorder. | Huang SY et al. | β | 2008 | β |
| New evidence for the association of the serotonin transporter gene (SLC6A4) haplotypes, threatening life events, and depressive phenotype. | Lazary J et al. | β | 2008 | β |
| Relationship of genetic variability and depressive symptoms to adverse events after coronary artery bypass graft surgery. | Phillips-Bute B et al. | β | 2008 | β |
| Rural environments reduce the genetic influence on adolescent substance use and rule-breaking behavior. | Legrand LN et al. | β | 2008 | β |
| Serotonergic function, two-mode models of self-regulation, and vulnerability to depression: what depression has in common with impulsive aggression. | Carver CS et al. | β | 2008 | β |
| Serotonin transporter (5-HTTLPR) genotype and amygdala activation: a meta-analysis. | MunafΓ² MR et al. | β | 2008 | β |
| Serotonin transporter genotype and depressive phenotype determination by discriminant analysis of glucose metabolism under acute tryptophan depletion. | Nugent AC et al. | β | 2008 | β |
| Socioeconomic background and the developmental course of schizotypal and borderline personality disorder symptoms. | Cohen P et al. | β | 2008 | β |
| The effect of 5-HTT gene promoter polymorphism on impulsivity depends on family relations in girls. | Paaver M et al. | β | 2008 | β |
| The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis. | Uher R et al. | β | 2008 | β |
| The modulatory influence of polymorphism of the serotonin transporter gene on characteristics of mental maladaptation in relatives of patients with endogenous psychoses. | Alfimova MV et al. | β | 2008 | β |
| The neural correlates of verbal encoding and retrieval in monozygotic twins at low or high risk for depression and anxiety. | Wolfensberger SP et al. | β | 2008 | β |
| The serotonin transporter polymorphisms and major depression following traumatic brain injury. | Chan F et al. | β | 2008 | β |
| What is the genetic relationship between anxiety and depression? | Hettema JM | β | 2008 | β |
| Women and major depressive disorder: clinical perspectives on causal pathways. | Accortt EE et al. | β | 2008 | β |
| Assessing gene-environment interactions on anxiety symptom subtypes across childhood and adolescence. | Lau JY et al. | β | 2007 | β |
| Association analyses of the serotonin transporter gene with lifetime depression and alcohol dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample. | Dick DM et al. | β | 2007 | β |
| Association of a serotonin transporter polymorphism (5-HTTLPR) with depression, perceived stress, and norepinephrine in patients with coronary disease: the Heart and Soul Study. | Otte C et al. | β | 2007 | β |
| A Trio of Concerns. | Kagan J | β | 2007 | β |
| Bad nature, bad nurture, and testimony regarding MAOA and SLC6A4 genotyping at murder trials. | Bernet W et al. | β | 2007 | β |
| Childhood adversity and youth depression: influence of gender and pubertal status. | Rudolph KD et al. | β | 2007 | β |
| [Depression and stress: is there an endophenotype?]. | Mello AF et al. | β | 2007 | β |
| Depressive symptoms in mid-pregnancy, lifetime stressors and the 5-HTTLPR genotype. | Scheid JM et al. | β | 2007 | β |
| Differential regulation of the serotonin transporter gene by lithium is mediated by transcription factors, CCCTC binding protein and Y-box binding protein 1, through the polymorphic intron 2 variable number tandem repeat. | Roberts J et al. | β | 2007 | β |
| Elevated serotonin transporter binding in major depressive disorder assessed using positron emission tomography and [11C]DASB; comparison with bipolar disorder. | Cannon DM et al. | β | 2007 | β |
| Evidence for a gene-gene interaction in predicting children's behavior problems: association of serotonin transporter short and dopamine receptor D4 long genotypes with internalizing and externalizing behaviors in typically developing 7-year-olds. | Schmidt LA et al. | β | 2007 | β |
| Gene-environment correlations: a review of the evidence and implications for prevention of mental illness. | Jaffee SR et al. | β | 2007 | β |
| Gene-environment interactions reexamined: does mother's marital stability interact with the dopamine receptor D2 gene in the etiology of childhood attention-deficit/hyperactivity disorder? | Waldman ID | β | 2007 | β |
| Genetically informative designs in the study of resilience in developmental psychopathology. | Bartels M et al. | β | 2007 | β |
| Genetic and environmental predictors of early alcohol use. | Kaufman J et al. | β | 2007 | β |
| Genetic expression outside the skin: clues to mechanisms of Genotype x Environment interaction. | Reiss D et al. | β | 2007 | β |
| Genetics, social behaviors, social environments and aging. | Harris JR | β | 2007 | β |
| Gene x Environment interactions in speech sound disorder predict language and preliteracy outcomes. | McGrath LM et al. | β | 2007 | β |
| Interaction between childhood trauma and serotonin transporter gene variation in suicide. | Roy A et al. | β | 2007 | β |
| Interaction between TPH1 and GNB3 genotypes and electroconvulsive therapy in major depression. | Anttila S et al. | β | 2007 | β |
| Interactions between life stressors and susceptibility genes (5-HTTLPR and BDNF) on depression in Korean elders. | Kim JM et al. | β | 2007 | β |
| Interactions of child maltreatment and serotonin transporter and monoamine oxidase A polymorphisms: depressive symptomatology among adolescents from low socioeconomic status backgrounds. | Cicchetti D et al. | β | 2007 | β |
| Interactive effects of the serotonin transporter 5-HTTLPR polymorphism and stressful life events on college student drinking and drug use. | Covault J et al. | β | 2007 | β |
| Intrapair differences in hippocampal volume in monozygotic twins discordant for the risk for anxiety and depression. | de Geus EJ et al. | β | 2007 | β |
| Long story short: the serotonin transporter in emotion regulation and social cognition. | Canli T et al. | β | 2007 | β |
| Mental health of young people: a global public-health challenge. | Patel V et al. | β | 2007 | β |
| Migraine comorbidity constellations. | Tietjen GE et al. | β | 2007 | β |
| Migraine headaches are not associated with a unique depressive symptom profile: results from the Baltimore Epidemiologic Catchment Area Study. | Kalaydjian A et al. | β | 2007 | β |
| Molecular genetics of bipolar disorder and depression. | Kato T | β | 2007 | β |
| Neurodevelopmental sequelae of postnatal maternal care in rodents: clinical and research implications of molecular insights. | Kaffman A et al. | β | 2007 | β |
| No interaction between the serotonin transporter polymorphism (5-HTTLPR) and childhood adversity or recent stressful life events on symptoms of depression: results from two community surveys. | Chipman P et al. | β | 2007 | β |
| Orbitofrontal cortex volume in late life depression: influence of hyperintense lesions and genetic polymorphisms. | Taylor WD et al. | β | 2007 | β |
| Parent-of-origin effects in attention-deficit hyperactivity disorder. | Goos LM et al. | β | 2007 | β |
| Relationship of 5-HTTLPR genotypes and depression risk in the presence of trauma in a female twin sample. | Chorbov VM et al. | β | 2007 | β |
| Resilience and developmental psychopathology. | Kim-Cohen J | β | 2007 | β |
| Review: Serotonin by stress interaction: a susceptibility factor for the development of depression? | Firk C et al. | β | 2007 | β |
| Role of stressful life events and menopausal stage in wellbeing and health. | Alexander JL et al. | β | 2007 | β |
| Serotonin transporter genotype (5-HTTLPR): effects of neutral and undefined conditions on amygdala activation. | Heinz A et al. | β | 2007 | β |
| Sleep quality varies as a function of 5-HTTLPR genotype and stress. | Brummett BH et al. | β | 2007 | β |
| The 5HTTLPR polymorphism, prior maltreatment and dramatic-erratic personality manifestations in women with bulimic syndromes. | Steiger H et al. | β | 2007 | β |
| The contribution of gene-environment interaction to psychopathology. | Thapar A et al. | β | 2007 | β |
| The emergence of genomic psychology. Insights from genomic analyses might allow psychologists to understand, predict and modify human behaviour. | Canli T | β | 2007 | β |
| The functional impact of SLC6 transporter genetic variation. | Hahn MK et al. | β | 2007 | β |
| The influence of urban/rural residency on depressive symptoms is moderated by the serotonin receptor 2A gene. | Jokela M et al. | β | 2007 | β |
| The long and the short of it: associations between 5-HTT genotypes and coping with stress. | Wilhelm K et al. | β | 2007 | β |
| The risk for depression conferred by stressful life events is modified by variation at the serotonin transporter 5HTTLPR genotype: evidence from the Spanish PREDICT-Gene cohort. | Cervilla JA et al. | β | 2007 | β |
| The serotonin receptor 2A gene moderates the influence of parental socioeconomic status on adulthood harm avoidance. | Jokela M et al. | β | 2007 | β |
| The serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults. | Kilpatrick DG et al. | β | 2007 | β |
| Tryptophan hydroxylase 1 gene (TPH1) moderates the influence of social support on depressive symptoms in adults. | Jokela M et al. | β | 2007 | β |
| Why smoking prevention programs sometimes fail. Does effectiveness depend on sociocultural context and individual characteristics? | Johnson CA et al. | β | 2007 | β |
| A cognitive vulnerability-stress perspective on bipolar spectrum disorders in a normative adolescent brain, cognitive, and emotional development context. | Alloy LB et al. | β | 2006 | β |
| Adolescent depression: description, causes, and interventions. | Hankin BL | β | 2006 | β |
| Association of a triallelic serotonin transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression. | Zalsman G et al. | β | 2006 | β |
| A twin-study of sleep difficulties in school-aged children. | Gregory AM et al. | β | 2006 | β |
| Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children. | Kaufman J et al. | β | 2006 | β |
| Changes in genetic and environmental influences on depressive symptoms across adolescence and young adulthood. | Lau JY et al. | β | 2006 | β |
| Common genetic vulnerability to depressive symptoms and coronary artery disease: a review and development of candidate genes related to inflammation and serotonin. | McCaffery JM et al. | β | 2006 | β |
| Developmental imaging genetics: challenges and promises for translational research. | Viding E et al. | β | 2006 | β |
| Early family environment, current adversity, the serotonin transporter promoter polymorphism, and depressive symptomatology. | Taylor SE et al. | β | 2006 | β |
| Effects of genes and stress on the neurobiology of depression. | Mann JJ et al. | β | 2006 | β |
| Emotional information processing in mood disorders: a review of behavioral and neuroimaging findings. | LeppΓ€nen JM | β | 2006 | β |
| Environmental control, social context, and individual differences in behavioral and cortisol responses to novelty in infant rhesus monkeys. | Roma PG et al. | β | 2006 | β |
| Examining the state-trait anxiety relationship: a behavioural genetic approach. | Lau JY et al. | β | 2006 | β |
| Family conflict interacts with genetic liability in predicting childhood and adolescent depression. | Rice F et al. | β | 2006 | β |
| Functional polymorphisms in dopamine and serotonin pathway genes. | D'Souza UM et al. | β | 2006 | β |
| Future prospects in depression research. | Holtzheimer PE et al. | β | 2006 | β |
| Gene-environment interactions in psychiatry: joining forces with neuroscience. | Caspi A et al. | β | 2006 | β |
| Gene-environment interplay and psychopathology: multiple varieties but real effects. | Rutter M et al. | β | 2006 | β |
| Genes making one feel blue in the flow of daily life: a momentary assessment study of gene-stress interaction. | Jacobs N et al. | β | 2006 | β |
| Genetic counseling in psychiatry. | Finn CT et al. | β | 2006 | β |
| Genetics of emotional regulation: the role of the serotonin transporter in neural function. | Hariri AR et al. | β | 2006 | β |
| Genotype x Environment interaction in psychopathology: fact or artifact? | Eaves LJ | β | 2006 | β |
| Imaging genetics: perspectives from studies of genetically driven variation in serotonin function and corticolimbic affective processing. | Hariri AR et al. | β | 2006 | β |
| I think, therefore I am: a twin study of attributional style in adolescents. | Lau JY et al. | β | 2006 | β |
| Life events, first depression onset and the serotonin transporter gene. | Wilhelm K et al. | β | 2006 | β |
| Measured Gene-Environment Interactions in Psychopathology: Concepts, Research Strategies, and Implications for Research, Intervention, and Public Understanding of Genetics. | Moffitt TE et al. | β | 2006 | β |
| Neural correlates of epigenesis. | Canli T et al. | β | 2006 | β |
| Neurobiology of depression in children and adolescents. | Zalsman G et al. | β | 2006 | β |
| Neuroimaging studies of serotonin gene polymorphisms: exploring the interplay of genes, brain, and behavior. | Brown SM et al. | β | 2006 | β |
| Possibilities for intervention in adolescents' and young adults' depression from a public health perspective. | Bramesfeld A et al. | β | 2006 | β |
| Serotonin transporter (5-HTTLPR) genotype, childhood abuse, and suicide attempts in adult psychiatric inpatients. | Gibb BE et al. | β | 2006 | β |
| Sleep and psychiatric disorders: future directions. | Krystal AD | β | 2006 | β |
| Social adversity, the serotonin transporter (5-HTTLPR) polymorphism and major depressive disorder. | Surtees PG et al. | β | 2006 | β |
| Social context and the psychobiology of posttraumatic stress. | Galea S et al. | β | 2006 | β |
| Stress and its consequences: an evolving story. | Kaufman J | β | 2006 | β |
| Stressful life events, 5-HTT genotype and risk of depression. | Zammit S et al. | β | 2006 | β |
| The IMAGE project: methodological issues for the molecular genetic analysis of ADHD. | Kuntsi J et al. | β | 2006 | β |
| Toward an Integration of Social and Biological Research. | McCutcheon VV | β | 2006 | β |
| Twin studies in pediatric depression. | Thapar A et al. | β | 2006 | β |
| 5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression. | Pezawas L et al. | β | 2005 | β |
| A monozygotic twin differences study of nonshared environmental influence on adolescent depressive symptoms. | Liang H et al. | β | 2005 | β |
| Current strategies for investigating the genetic and environmental risk factors for affective disorders. | Farmer A et al. | β | 2005 | β |
| Environmentally mediated risks for psychopathology: research strategies and findings. | Rutter M | β | 2005 | β |
| Finding genes in child psychology and psychiatry: when are we going to be there? | Plomin R | β | 2005 | β |
| Genetic and environmental influences on Anxious/Depression during childhood: a study from the Netherlands Twin Register. | Boomsma DI et al. | β | 2005 | β |
| Introductory guide to the statistics of molecular genetics. | Eley TC et al. | β | 2005 | β |
| Psychiatry and the 'new genetics': hunting for genes for behaviour and drug response. | Aitchison KJ et al. | β | 2005 | β |
| Role of the serotonin transporter gene and family function in adolescent alcohol consumption. | Nilsson KW et al. | β | 2005 | β |
| The genetics of depression and related traits. | Huezo-Diaz P et al. | β | 2005 | β |
| The serotonin transporter length polymorphism, neuroticism, and depression: a comprehensive assessment of association. | Willis-Owen SA et al. | β | 2005 | β |
| No association between dopamine D4 receptor gene variants and novelty seeking. | JΓΆnsson EG et al. | β | 2002 | β |