Evaluation of psychopathological conditions in children with heavy prenatal alcohol exposure.
- Authors
- Fryer, Susanna L; McGee, Christie L; Matt, Georg E; Riley, Edward P; Mattson, Sarah N
- Year
- 2007
- Journal
- Pediatrics
- PMID
- 17332190
- DOI
- 10.1542/peds.2006-1606
OBJECTIVE: This study compared the prevalence of psychopathological conditions in children with heavy prenatal alcohol exposure (N = 39) and nonexposed, typically developing peers (N = 30), matched with respect to age, gender, and socioeconomic status. METHODS: Caregivers were interviewed with either the Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children, Present and Lifetime Version, or the Computerized Diagnostic Interview Schedule for Children, Version IV. Statistical resampling methods were used to create 95% confidence intervals for the difference between the proportions of children with psychopathological conditions in the exposed and control groups. RESULTS: Group differences were seen in the attention-deficit/hyperactivity disorder, depressive disorders, oppositional defiant disorder, conduct disorder, and specific phobia outcome categories. The group difference in the attention-deficit/hyperactivity disorder category was by far the largest effect observed. CONCLUSIONS: These results suggest that fetal alcohol exposure should be considered a possible factor in the pathogenesis of childhood psychiatric disorders. These data provide clinically relevant information about the mental health problems that children with fetal alcohol exposure are likely to face.
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