Regulation of dendritic development by neuron-specific chromatin remodeling complexes.
paper
Cited
Public
Unavailable
- Authors
- Wu, Jiang I; Lessard, Julie; Olave, Ivan A; Qiu, Zilong; Ghosh, Anirvan; Graef, Isabella A; Crabtree, Gerald R
- Year
- 2007
- Journal
- Neuron
- PMID
- 17920018
- DOI
- 10.1016/j.neuron.2007.08.021
The diversity of dendritic patterns is one of the fundamental characteristics of neurons and is in part regulated by transcriptional programs initiated by electrical activity. We show that dendritic outgrowth requires a family of combinatorially assembled, neuron-specific chromatin remodeling complexes (nBAF complexes) distinguished by the actin-related protein BAF53b and based on the Brg/Brm ATPases. nBAF complexes bind tightly to the Ca(2+)-responsive dendritic regulator CREST and directly regulate genes essential for dendritic outgrowth. BAF53b is not required for nBAF complex assembly or the interaction with CREST, yet is required for their recruitment to the promoters of specific target genes. The highly homologous BAF53a protein, which is a component of neural progenitor and nonneural BAF complexes, cannot replace BAF53b's role in dendritic development. Remarkably, we find that this functional specificity is conferred by the actin fold subdomain 2 of BAF53b. These studies suggest that the genes encoding the individual subunits of BAF complexes function like letters in a ten-letter word to produce biologically specific meanings (in this case dendritic outgrowth) by combinatorial assembly of their products.
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| The sequence-specific transcription factor c-Jun targets Cockayne syndrome protein B to regulate transcription and chromatin structure. | Lake RJ et al. | β | 2014 | β |
| The SWI/SNF genetic blockade: effects in cell differentiation, cancer and developmental diseases. | Romero OA et al. | β | 2014 | β |
| Vulnerabilities of mutant SWI/SNF complexes in cancer. | Helming KC et al. | β | 2014 | β |
| Cell-intrinsic drivers of dendrite morphogenesis. | Puram SV et al. | β | 2013 | β |
| Creating a neural specific chromatin landscape by npBAF and nBAF complexes. | Staahl BT et al. | β | 2013 | β |
| CRESTing the ALS mountain. | Renton AE et al. | β | 2013 | β |
| Epigenetic control of skeletal muscle regeneration: Integrating genetic determinants and environmental changes. | Giordani L et al. | β | 2013 | β |
| Epigenetic dynamics in psychiatric disorders: environmental programming of neurodevelopmental processes. | Kofink D et al. | β | 2013 | β |
| Exome sequencing to identify de novo mutations in sporadic ALS trios. | Chesi A et al. | β | 2013 | β |
| From neural development to cognition: unexpected roles for chromatin. | Ronan JL et al. | β | 2013 | β |
| Histone regulation in the CNS: basic principles of epigenetic plasticity. | Maze I et al. | β | 2013 | β |
| Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways. | Staahl BT et al. | β | 2013 | β |
| MicroRNAs: regulators of neuronal fate. | Sun AX et al. | β | 2013 | β |
| miR-9*- and miR-124a-Mediated switching of chromatin remodelling complexes is altered in rat spina bifida aperta. | Wei X et al. | β | 2013 | β |
| NF-ΞΊB forms a complex with the chromatin remodeler BRG1 to regulate Schwann cell differentiation. | Limpert AS et al. | β | 2013 | β |
| Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation. | Yu Y et al. | β | 2013 | β |
| Reprogramming human fibroblasts to neurons by recapitulating an essential microRNA-chromatin switch. | Tang J et al. | β | 2013 | β |
| Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma. | Kadoch C et al. | β | 2013 | β |
| Structure, function and regulation of CSB: a multi-talented gymnast. | Lake RJ et al. | β | 2013 | β |
| The BAF complex interacts with Pax6 in adult neural progenitors to establish a neurogenic cross-regulatory transcriptional network. | Ninkovic J et al. | β | 2013 | β |
| The Drosophila transcription factor Adf-1 (nalyot) regulates dendrite growth by controlling FasII and Staufen expression downstream of CaMKII and neural activity. | Timmerman C et al. | β | 2013 | β |
| The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory. | Vogel-Ciernia A et al. | β | 2013 | β |
| The SWI/SNF chromatin remodeling complex selectively affects multiple aspects of serotonergic neuron differentiation. | Weinberg P et al. | β | 2013 | β |
| Aberrant epigenetic landscape in intellectual disability. | Sanchez-Mut JV et al. | β | 2012 | β |
| Akirin: a context-dependent link between transcription and chromatin remodeling. | Nowak SJ et al. | β | 2012 | β |
| Chromatin remodeling during glucocorticoid receptor regulated transactivation. | King HA et al. | β | 2012 | β |
| Current status and future prospects for epigenetic psychopharmacology. | Boks MP et al. | β | 2012 | β |
| Diverse functions of ATP-dependent chromatin remodeling complexes in development and cancer. | Wu JI | β | 2012 | β |
| Epigenetic control on cell fate choice in neural stem cells. | Hu XL et al. | β | 2012 | β |
| Epigenetic regulation of axon and dendrite growth. | Trakhtenberg EF et al. | β | 2012 | β |
| Epigenetics: judge, jury and executioner of stem cell fate. | Tollervey JR et al. | β | 2012 | β |
| Epigenetics of pluripotent cells. | Medvedev SP et al. | β | 2012 | β |
| EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear. | Ahmed M et al. | β | 2012 | β |
| Heterocomplex formation by Arp4 and Ξ²-actin is involved in the integrity of the Brg1 chromatin remodeling complex. | Nishimoto N et al. | β | 2012 | β |
| Lighting a path: genetic studies pinpoint neurodevelopmental mechanisms in autism and related disorders. | Pescosolido MF et al. | β | 2012 | β |
| Molecular mechanisms of dendrite morphogenesis. | Arikkath J | β | 2012 | β |
| Regulation of gene expression during early neuronal differentiation: evidence for patterns conserved across neuron populations and vertebrate classes. | Ernsberger U | β | 2012 | β |
| Signal-dependent incorporation of MyoD-BAF60c into Brg1-based SWI/SNF chromatin-remodelling complex. | Forcales SV et al. | β | 2012 | β |
| The BAF53a subunit of SWI/SNF-like BAF complexes is essential for hemopoietic stem cell function. | Krasteva V et al. | β | 2012 | β |
| The chromatin-remodeling enzymes BRG1 and CHD4 antagonistically regulate vascular Wnt signaling. | Curtis CD et al. | β | 2012 | β |
| Actin-related proteins localized in the nucleus: from discovery to novel roles in nuclear organization. | Oma Y et al. | β | 2011 | β |
| ATP-dependent chromatin remodeling: genetics, genomics and mechanisms. | Hargreaves DC et al. | β | 2011 | β |
| CHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genes. | Potts RC et al. | β | 2011 | β |
| Chromatin remodeling in cardiovascular development and physiology. | Han P et al. | β | 2011 | β |
| Combinatorial assembly and function of chromatin regulatory complexes. | Lange M et al. | β | 2011 | β |
| CREB in adult neurogenesis--master and partner in the development of adult-born neurons? | Merz K et al. | β | 2011 | β |
| Dual role of Brg chromatin remodeling factor in Sonic hedgehog signaling during neural development. | Zhan X et al. | β | 2011 | β |
| Engineering the ABA plant stress pathway for regulation of induced proximity. | Liang FS et al. | β | 2011 | β |
| Global analysis of gene expression in the developing brain of Gtf2ird1 knockout mice. | O'Leary J et al. | β | 2011 | β |
| Interactions of transcription factors with chromatin. | van Bakel H | β | 2011 | β |
| Intrinsic epigenetic factors cooperate with the steroid hormone ecdysone to govern dendrite pruning in Drosophila. | Kirilly D et al. | β | 2011 | β |
| MicroRNA-mediated conversion of human fibroblasts to neurons. | Yoo AS et al. | β | 2011 | β |
| Neuronal activity-regulated gene transcription in synapse development and cognitive function. | West AE et al. | β | 2011 | β |
| Nuclear receptor coregulators merge transcriptional coregulation with epigenetic regulation. | Kato S et al. | β | 2011 | β |
| Post-transcription initiation function of the ubiquitous SAGA complex in tissue-specific gene activation. | Weake VM et al. | β | 2011 | β |
| Regulation of nucleosome landscape and transcription factor targeting at tissue-specific enhancers by BRG1. | Hu G et al. | β | 2011 | β |
| Smarcd3b and Gata5 promote a cardiac progenitor fate in the zebrafish embryo. | Lou X et al. | β | 2011 | β |
| SWI/SNF nucleosome remodellers and cancer. | Wilson BG et al. | β | 2011 | β |
| The chromatin-remodeling enzyme BRG1 modulates vascular Wnt signaling at two levels. | Griffin CT et al. | β | 2011 | β |
| The chromatin remodeling factor Bap55 functions through the TIP60 complex to regulate olfactory projection neuron dendrite targeting. | Tea JS et al. | β | 2011 | β |
| The mental retardation associated protein, srGAP3 negatively regulates VPA-induced neuronal differentiation of Neuro2A cells. | Chen K et al. | β | 2011 | β |
| Transcriptional controls by nuclear fat-soluble vitamin receptors through chromatin reorganization. | Kato S et al. | β | 2011 | β |
| Transcriptional regulation of neuronal polarity and morphogenesis in the mammalian brain. | de la Torre-Ubieta L et al. | β | 2011 | β |
| Alternative splicing of the histone demethylase LSD1/KDM1 contributes to the modulation of neurite morphogenesis in the mammalian nervous system. | Zibetti C et al. | β | 2010 | β |
| Branching out: mechanisms of dendritic arborization. | Jan YN et al. | β | 2010 | β |
| Carboxypeptidase E knockout mice exhibit abnormal dendritic arborization and spine morphology in central nervous system neurons. | Woronowicz A et al. | β | 2010 | β |
| Chromatin regulatory mechanisms in pluripotency. | Lessard JA et al. | β | 2010 | β |
| Chromatin remodeling in heart development. | Bruneau BG | β | 2010 | β |
| Chromatin remodelling during development. | Ho L et al. | β | 2010 | β |
| Deconstructing repression: evolving models of co-repressor action. | Perissi V et al. | β | 2010 | β |
| Dynamic epigenetic regulation in neurons: enzymes, stimuli and signaling pathways. | Riccio A | β | 2010 | β |
| Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: unraveling the genome to understand the mind. | Hsieh J et al. | β | 2010 | β |
| Epigenetics to proteomics: from yeast to brain. | Bhargava P | β | 2010 | β |
| Hippocampus development and function: role of epigenetic factors and implications for cognitive disease. | Lagali PS et al. | β | 2010 | β |
| Nuclear ataxias. | Orr HT | β | 2010 | β |
| Postnatal development enhances the effects of cholinergic inputs on recruitment threshold and firing rate of rat oculomotor nucleus motoneurons. | Carrascal L et al. | β | 2010 | β |
| SMARCA2 and other genome-wide supported schizophrenia-associated genes: regulation by REST/NRSF, network organization and primate-specific evolution. | Loe-Mie Y et al. | β | 2010 | β |
| SWI/SNF complexes, chromatin remodeling and skeletal myogenesis: it's time to exchange! | Albini S et al. | β | 2010 | β |
| The role of calcium-dependent gene expression in autism spectrum disorders: lessons from MeCP2, Ube3a and beyond. | Qiu Z et al. | β | 2010 | β |
| The transcriptional control of female puberty. | Ojeda SR et al. | β | 2010 | β |
| UV-induced association of the CSB remodeling protein with chromatin requires ATP-dependent relief of N-terminal autorepression. | Lake RJ et al. | β | 2010 | β |
| Activator-binding domains of the SWI/SNF chromatin remodeling complex characterized in vitro are required for its recruitment to promoters in vivo. | Ferreira ME et al. | β | 2009 | β |
| An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency. | Ho L et al. | β | 2009 | β |
| ATP-dependent chromatin remodeling in neural development. | Yoo AS et al. | β | 2009 | β |
| A vertebrate Polycomb response element governs segmentation of the posterior hindbrain. | Sing A et al. | β | 2009 | β |
| Basic molecular fingerprinting of immature cerebellar cortical inhibitory interneurons and their precursors. | Glassmann A et al. | β | 2009 | β |
| Changes in somatodendritic morphometry of rat oculomotor nucleus motoneurons during postnatal development. | Carrascal L et al. | β | 2009 | β |
| Chapter 5. Nuclear actin-related proteins in epigenetic control. | Meagher RB et al. | β | 2009 | β |
| Chromatin remodelling beyond transcription: the INO80 and SWR1 complexes. | Morrison AJ et al. | β | 2009 | β |
| Developmental biology: The early heart remodelled. | Liang FS et al. | β | 2009 | β |
| Induction of TLR4-target genes entails calcium/calmodulin-dependent regulation of chromatin remodeling. | Lai D et al. | β | 2009 | β |
| MicroRNA-mediated switching of chromatin-remodelling complexes in neural development. | Yoo AS et al. | β | 2009 | β |
| Molecular basis of CD4 repression by the Swi/Snf-like BAF chromatin remodeling complex. | Wan M et al. | β | 2009 | β |
| Molecules and mechanisms of dendrite development in Drosophila. | Corty MM et al. | β | 2009 | β |
| Recruitment of the SWI/SNF chromatin remodeling complex to steroid hormone-regulated promoters by nuclear receptor coactivator flightless-I. | Jeong KW et al. | β | 2009 | β |
| Sex differences in histone modifications in the neonatal mouse brain. | Tsai HW et al. | β | 2009 | β |
| Shifting players and paradigms in cell-specific transcription. | D'Alessio JA et al. | β | 2009 | β |
| The biology of chromatin remodeling complexes. | Clapier CR et al. | β | 2009 | β |
| Understanding the words of chromatin regulation. | Wu JI et al. | β | 2009 | β |
| Variations in the composition of mammalian SWI/SNF chromatin remodelling complexes. | Ryme J et al. | β | 2009 | β |
| A brief history of neuronal gene expression: regulatory mechanisms and cellular consequences. | Qiu Z et al. | β | 2008 | β |
| A calcium-dependent switch in a CREST-BRG1 complex regulates activity-dependent gene expression. | Qiu Z et al. | β | 2008 | β |
| A novel genetic strategy reveals unexpected roles of the Swi-Snf-like chromatin-remodeling BAF complex in thymocyte development. | Jani A et al. | β | 2008 | β |
| Baf60c is a component of the neural progenitor-specific BAF complex in developing retina. | Lamba DA et al. | β | 2008 | β |
| Beyond transcription factors: the role of chromatin modifying enzymes in regulating transcription required for memory. | Barrett RM et al. | β | 2008 | β |
| Chromatin remodelling and actin organisation. | Farrants AK | β | 2008 | β |
| Combinatorial assembly of neurons: from chromatin to dendrites. | de la Torre-Ubieta L et al. | β | 2008 | β |
| Coronary development is regulated by ATP-dependent SWI/SNF chromatin remodeling component BAF180. | Huang X et al. | β | 2008 | β |
| ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a. | Gao X et al. | β | 2008 | β |
| Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast. | Monahan BJ et al. | β | 2008 | β |
| Message in a nucleus: signaling to the transcriptional machinery. | Carrera I et al. | β | 2008 | β |
| Quantitative analysis of brain nuclear phosphoproteins identifies developmentally regulated phosphorylation events. | Liao L et al. | β | 2008 | β |
| Two subunits specific to the PBAP chromatin remodeling complex have distinct and redundant functions during drosophila development. | Carrera I et al. | β | 2008 | β |