A twin study of genetic and environmental influences on tobacco initiation, regular tobacco use and nicotine dependence.
paper
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- Authors
- Maes, Hermine H; Sullivan, Patrick F; Bulik, Cynthia M; Neale, Michael C; Prescott, Carol A; Eaves, Lindon J; Kendler, Kenneth S
- Year
- 2004
- Journal
- Psychological medicine
- PMID
- 15697051
- DOI
- 10.1017/s0033291704002405
BACKGROUND: Numerous twin studies have reported significant genetic contributions to the variability of tobacco initiation (TI), while fewer studies have shown similar results for the persistence of smoking behavior, or nicotine dependence (ND). As the development of ND requires regular tobacco use (RTU) which in turn requires TI, a conditional approach is necessary. METHOD: We used structural equation modeling of multi-step conditional processes to examine the relationship between genetic and environmental risk factors for TI, RTU and ND. The tobacco variables were assessed by personal interview in female, male and opposite-sex twin pairs from the population-based Virginia Twin Registry. RESULTS: The results suggested that the liabilities to TI, RTU and ND were correlated. Over 80 % of the variance in liability to TI and RTU were shared, and a smaller proportion was shared between RTU and ND. The heritabilities were estimated at 75 %, 80 % and 60 % respectively for TI, RTU and ND. The variance specific to liability to RTU was entirely accounted for by additive genetic factors. Only a modest part of the heritability in liability of ND was due to genetic factors specific to ND. Shared environmental factors were not significant. No sex differences were found for the sources of variation or causal paths, but prevalences were significantly greater in males versus females. CONCLUSIONS: This study showed significant overlap in the contribution of genetic factors to individual differences in TI, RTU and ND. Furthermore, there was evidence for significant additional genetic factors specific to RTU and ND.
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|---|---|---|---|---|
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| Computationally efficient methods for estimating phenome-wide coheritability of multi-type phenotypes using biobank data. | Deng Y et al. | β | 2025 | β |
| Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits. | Johnson EC et al. | β | 2025 | β |
| Nicotine reward in the conditioned place preference test across a panel of male inbred mice and F1 crosses: genetic influence and correlation with variation in nicotine antinociception. | Buzzi B et al. | β | 2025 | β |
| "Unraveling the role of <i>CHRNA6</i>, the neuronal Ξ±6 nicotinic acetylcholine receptor subunit". | Heydary YH et al. | β | 2025 | β |
| A Bivariate Twin Study of Lifetime cannabis Initiation and Lifetime Regular Tobacco Smoking Across Three Different Countries. | Zellers S et al. | β | 2024 | β |
| An ontological framework for organising and describing behaviours: The Human Behaviour Ontology | Schenk PM et al. | β | 2024 | β |
| An ontological framework for organising and describing behaviours: The Human Behaviour Ontology. | Schenk PM et al. | β | 2024 | β |
| Association of monoaminergic gene polymorphisms in chronic inflammatory pulmonary disease patients with successful smoking cessation. | Mikaczo A et al. | β | 2024 | β |
| Cohort Effects on Tobacco Consumption and Its Genetic and Environmental Variance Among Finnish Adults Born Between 1880 and 1957. | Zellers S et al. | β | 2024 | β |
| Familial effects account for association between chronic pain and past month smoking. | Rader L et al. | β | 2024 | β |
| Gene-environment transactions between peer cigarette use, parental supervision, and Chinese adolescent cigarette smoking initiation. | Meyer Z et al. | β | 2024 | β |
| Candidate gene-environment interactions in substance abuse: A systematic review. | Jiang Z et al. | β | 2023 | β |
| Genetic and Cultural Transmission of Alcohol Use Disorder in Swedish Twin Pedigrees. | Maes HH et al. | β | 2023 | β |
| Genetic and environmental influences on early-age susceptibility and initiation of nicotine-containing product use: A twin-pairs study. | Kochvar A et al. | β | 2023 | β |
| The shared genetic architecture of smoking behaviours and psychiatric disorders: evidence from a population-based longitudinal study in England. | Ajnakina O et al. | β | 2023 | β |
| Examining the role of mitochondrial genetic variation in nicotine dependence. | Giannoulis SV et al. | β | 2022 | β |
| Polygenic score for cigarette smoking is associated with ever electronic-cigarette use in a college-aged sample. | Cooke ME et al. | β | 2022 | β |
| Serotonin Receptor <i>HTR3A</i> Gene Polymorphisms rs1985242 and rs1062613, E-Cigarette Use and Personality. | Suchanecka A et al. | β | 2022 | β |
| The genetic aetiology of cannabis use: from twin models to genome-wide association studies and beyond. | Verweij KJH et al. | β | 2022 | β |
| Clarifying the Genetic Influences on Nicotine Dependence and Quantity of Use in Cigarette Smokers. | Verhulst B et al. | β | 2021 | β |
| Gene-based association analysis reveals involvement of LAMA5 and cell adhesion pathways in nicotine dependence in African- and European-American samples. | Fan R et al. | β | 2021 | β |
| Genome-wide analyses of smoking behaviors in schizophrenia: Findings from the Psychiatric Genomics Consortium. | Peterson RE et al. | β | 2021 | β |
| The association between internalizing and externalizing severity with current use of cigarettes, e-cigarettes, and alcohol in adults: Wave 1 of the Population Assessment of Tobacco and Health (PATH) study. | Blondino CT et al. | β | 2021 | β |
| Using Multimodel Inference/Model Averaging to Model Causes of Covariation Between Variables in Twins. | Maes HH et al. | β | 2021 | β |
| Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): II. Externalizing superspectrum. | Krueger RF et al. | β | 2021 | β |
| Genetic interaction between two VNTRs in the MAOA gene is associated with the nicotine dependence. | KΓ΅ks G et al. | β | 2020 | β |
| Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals. | Xu K et al. | β | 2020 | β |
| Investigating the genetic and causal relationship between initiation or use of alcohol, caffeine, cannabis and nicotine. | Chang LH et al. | β | 2020 | β |
| Modeling Etiology of Smoking During Pregnancy in Swedish Twins, Full-, and Half-Siblings, Reared Together and Apart. | Maes HH et al. | β | 2020 | β |
| Role of genetic background in the effects of adolescent nicotine exposure on mesolimbic dopamine transmission. | Cadoni C et al. | β | 2020 | β |
| The Genetics of Externalizing Problems. | Barr PB et al. | β | 2020 | β |
| Do women expose themselves to more health-related risks in certain phases of the menstrual cycle? A meta-analytic review. | Boudesseul J et al. | β | 2019 | β |
| Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and AlcoholΒ Use. | Brazel DM et al. | β | 2019 | β |
| Genetic and environmental risk factors in the non-medical use of over-the-counter or prescribed analgesics, and their relationship to major classes of licit and illicit substance use and misuse in a population-based sample of young adult twins. | Gillespie NA et al. | β | 2019 | β |
| Genetic variation in health insurance coverage. | Wehby GL et al. | β | 2019 | β |
| Tobacco and cannabis use in college students are predicted by sex-dimorphic interactions between MAOA genotype and child abuse. | Fite PJ et al. | β | 2019 | β |
| umx: Twin and Path-Based Structural Equation Modeling in R. | Bates TC et al. | β | 2019 | β |
| Identifying the contribution of prenatal risk factors to offspring development and psychopathology: What designs to use and a critique of literature on maternal smoking and stress in pregnancy. | Rice F et al. | β | 2018 | β |
| Telomere length in psychiatric disorders: Is it more than an ageing marker? | Monroy-Jaramillo N et al. | β | 2018 | β |
| The Speed of Progression to Tobacco and Alcohol Dependence: A Twin Study. | Huggett SB et al. | β | 2018 | β |
| The utility of twins in developmental cognitive neuroscience research: How twins strengthen the ABCD research design. | Iacono WG et al. | β | 2018 | β |
| A Genetic Epidemiological Mega Analysis of Smoking Initiation in Adolescents. | Maes HH et al. | β | 2017 | β |
| A Novel Tobacco Use Phenotype Suggests the 15q25 and 19q13 Loci May be Differentially Associated With Cigarettes per Day and Tobacco-Related Problems. | Richmond-Rakerd LS et al. | β | 2017 | β |
| Genotype Γ Environment Interaction in Smoking Behaviors: A Systematic Review. | Do EK et al. | β | 2017 | β |
| The genetic epidemiology of substance use disorder: A review. | Prom-Wormley EC et al. | β | 2017 | β |
| The risk of cancer in the offspring and parental length of life. | Del Risco Kollerud R et al. | β | 2017 | β |
| Age at first use and later substance use disorder: Shared genetic and environmental pathways for nicotine, alcohol, and cannabis. | Richmond-Rakerd LS et al. | β | 2016 | β |
| A Longitudinal Adoption Study of Substance Use Behavior in Adolescence. | Huibregtse BM et al. | β | 2016 | β |
| Association Between CHRNA3 and CHRNA5 Nicotine Receptor Subunit Gene Variants and Nicotine Dependence in an Isolated Populationof Kashubians in Poland. | Kita-Milczarska K et al. | β | 2016 | β |
| Association between smoking behaviour and genetic variants of glial cell line-derived neurotrophic factor. | Kotyuk E et al. | β | 2016 | β |
| Associations between depression risk, bullying and current smoking among Chinese adolescents: Modulated by gender. | Guo L et al. | β | 2016 | β |
| CHRNA5/A3/B4 Variant rs3743078 and Nicotine-Related Phenotypes: Indirect Effects Through Nicotine Craving. | Shmulewitz D et al. | β | 2016 | β |
| Contribution of Variants in CHRNA5/A3/B4 Gene Cluster on Chromosome 15 to Tobacco Smoking: From Genetic Association to Mechanism. | Wen L et al. | β | 2016 | β |
| Crucial roles of the CHRNB3-CHRNA6 gene cluster on chromosome 8 in nicotine dependence: update and subjects for future research. | Wen L et al. | β | 2016 | β |
| Dopamine D4 receptor VNTR polymorphism associated with greater risk for substance abuse among adolescents with disruptive behavior disorders: Preliminary results. | Mallard TT et al. | β | 2016 | β |
| Emotional and Affective Temperaments in Smoking Candidates for Bariatric Surgery. | Mombach KD et al. | β | 2016 | β |
| Fischer 344 and Lewis Rat Strains as a Model of Genetic Vulnerability to Drug Addiction. | Cadoni C | β | 2016 | β |
| Genetic and environmental components to self-induced vomiting. | Peterson CM et al. | β | 2016 | β |
| Genetic imaging consortium for addiction medicine: From neuroimaging to genes. | Mackey S et al. | β | 2016 | β |
| Genome-Wide Association of the Laboratory-Based Nicotine Metabolite Ratio in Three Ancestries. | Baurley JW et al. | β | 2016 | β |
| Genome-wide significant loci for addiction and anxiety. | Hodgson K et al. | β | 2016 | β |
| Narrative review of genes, environment, and cigarettes. | Do E et al. | β | 2016 | β |
| Progression of nicotine dependence, mood level, and mood variability in adolescent smokers. | Piasecki TM et al. | β | 2016 | β |
| Racial differences in heritability of cigarette smoking in adolescents and young adults. | Bares CB et al. | β | 2016 | β |
| Amphetamine self-administration and dopamine function: assessment of geneβΓβenvironment interactions in Lewis and Fischer 344 rats. | Meyer AC et al. | β | 2015 | β |
| Association of 5-HTTLPR polymorphism with smoking behaviors: A meta-analysis. | Li H et al. | β | 2015 | β |
| A Systematic Analysis of Candidate Genes Associated with Nicotine Addiction. | Liu M et al. | β | 2015 | β |
| Candidate gene study for smoking, alcohol use, and body weight in a sample of pregnant women. | Wehby GL et al. | β | 2015 | β |
| COMT polymorphism modulates the resting-state EEG alpha oscillatory response to acute nicotine in male non-smokers. | Bowers H et al. | β | 2015 | β |
| Developmental Changes in Genetic and Shared Environmental Contributions to Smoking Initiation and Subsequent Smoking Quantity in Adolescence and Young Adulthood. | Bares CB et al. | β | 2015 | β |
| Genetic and environmental contributions to initiation of cigarette smoking in young African-American and European-American women. | Sartor CE et al. | β | 2015 | β |
| Genetic and environmental influences on adolescents' smoking involvement: a multi-informant twin study. | Seglem KB et al. | β | 2015 | β |
| Genetic and Environmental Influences on Smoking Behavior across Adolescence and Young Adulthood in the Virginia Twin Study of Adolescent Behavioral Development and the Transitions to Substance Abuse Follow-Up. | Do EK et al. | β | 2015 | β |
| Genetics of smoking behaviour. | Ware JJ et al. | β | 2015 | β |
| Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans. | Gelernter J et al. | β | 2015 | β |
| Nicotine dependence in an isolated population of Kashubians from North Poland: a population survey. | Sieminska A et al. | β | 2015 | β |
| Prevention, Use of Health Services, and Genes: Implications of Genetics for Policy Formation. | Wehby GL et al. | β | 2015 | β |
| The Ξ²3 subunit of the nicotinic acetylcholine receptor: Modulation of gene expression and nicotine consumption. | Kamens HM et al. | β | 2015 | β |
| A multivariate twin study of the dimensions of religiosity and common psychiatric and substance use disorders. | Vance T et al. | β | 2014 | β |
| Electronic cigarettes: a review of safety and clinical issues. | Weaver M et al. | β | 2014 | β |
| Genetic Association of CHRNB3 and CHRNA6 Gene Polymorphisms with Nicotine Dependence Syndrome Scale in Korean Population. | Won WY et al. | β | 2014 | β |
| Genetic variation in personality traits explains genetic overlap between borderline personality features and substance use disorders. | Few LR et al. | β | 2014 | β |
| Risk factors influencing smoking behavior: a Turkish twin study. | Oncel SY et al. | β | 2014 | β |
| Significant associations of CHRNA2 and CHRNA6 with nicotine dependence in European American and African American populations. | Wang S et al. | β | 2014 | β |
| A Comparison of Factor Score Estimation Methods in the Presence of Missing Data: Reliability and an Application to Nicotine Dependence. | Estabrook R et al. | β | 2013 | β |
| Adolescent peer choice and cigarette smoking: evidence of active gene-environment correlation? | Wills AG et al. | β | 2013 | β |
| A genomewide association study of smoking relapse in four European population-based samples. | Tozzi F et al. | β | 2013 | β |
| Early smoking onset and risk for subsequent nicotine dependence: a monozygotic co-twin control study. | Kendler KS et al. | β | 2013 | β |
| Exploring alternate processes contributing to the association between maternal smoking and the smoking behavior among young adult offspring. | Selya AS et al. | β | 2013 | β |
| Nine generations of selection for high and low nicotine intake in outbred Sprague-Dawley rats. | Nesil T et al. | β | 2013 | β |
| Persistent smoking as a predictor of disability pension due to musculoskeletal diagnoses: a 23 year prospective study of Finnish twins. | Ropponen A et al. | β | 2013 | β |
| Serotonin transporter and receptor genes significantly impact nicotine dependence through genetic interactions in both European American and African American smokers. | Yang Z et al. | β | 2013 | β |
| The Impact of Cigarette Quitting during Pregnancy on Other Prenatal Health Behaviors. | Wehby GL et al. | β | 2013 | β |
| ANAPC1 and SLCO3A1 are associated with nicotine dependence: meta-analysis of genome-wide association studies. | Wang KS et al. | β | 2012 | β |
| An association between the serotonin transporter gene promoter polymorphism and smoking cessation among Japanese males. | Sekiguchi F et al. | β | 2012 | β |
| Associations between substance use disorders and major depression in parents and late adolescent-emerging adult offspring: an adoption study. | Marmorstein NR et al. | β | 2012 | β |
| A systematic review of the A118G (Asn40Asp) variant of OPRM1 in relation to smoking initiation, nicotine dependence and smoking cessation. | Verhagen M et al. | β | 2012 | β |
| Borderline personality traits and substance use: genetic factors underlie the association with smoking and ever use of cannabis, but not with high alcohol consumption. | Distel MA et al. | β | 2012 | β |
| Genetic analyses of smoking initiation, persistence, quantity, and age-at-onset of regular cigarette use in Brazilian families: the Baependi Heart Study. | Horimoto AR et al. | β | 2012 | β |
| Genetic and environmental etiology of nicotine use in Sri Lankan male twins. | Zavos HM et al. | β | 2012 | β |
| Genetic etiology of the common liability to drug dependence: evidence of common and specific mechanisms for DSM-IV dependence symptoms. | Palmer RH et al. | β | 2012 | β |
| Parent, sibling and peer influences on smoking initiation, regular smoking and nicotine dependence. Results from a genetically informative design. | Scherrer JF et al. | β | 2012 | β |
| Recent advances in the genetic epidemiology and molecular genetics of substance use disorders. | Kendler KS et al. | β | 2012 | β |
| Risk factors for adolescent smoking: parental smoking and the mediating role of nicotine dependence. | Selya AS et al. | β | 2012 | β |
| Smoking and body weight: evidence using genetic instruments. | Wehby GL et al. | β | 2012 | β |
| Smoking cessation pharmacogenetics: analysis of varenicline and bupropion in placebo-controlled clinical trials. | King DP et al. | β | 2012 | β |
| Social determinants of smoking behavior: the Healthy Twin Study, Korea. | Kim YS et al. | β | 2012 | β |
| Suicidal behavior, smoking, and familial vulnerability. | Scherrer JF et al. | β | 2012 | β |
| The CHRNA5-A3-B4 gene cluster in nicotine addiction. | Berrettini WH et al. | β | 2012 | β |
| The co-occurring use and misuse of cannabis and tobacco: a review. | Agrawal A et al. | β | 2012 | β |
| The interplay of genes and adolescent development in substance use disorders: leveraging findings from GWAS meta-analyses to test developmental hypotheses about nicotine consumption. | Vrieze SI et al. | β | 2012 | β |
| Transitions in smoking behaviour and the design of cessation schemes. | Grasman J et al. | β | 2012 | β |
| A genetic instrumental variables analysis of the effects of prenatal smoking on birth weight: evidence from two samples. | Wehby GL et al. | β | 2011 | β |
| A population-based twin study of the genetic and environmental relationship of major depression, regular tobacco use and nicotine dependence. | Edwards AC et al. | β | 2011 | β |
| A twin association study of nicotine dependence with markers in the CHRNA3 and CHRNA5 genes. | Maes HH et al. | β | 2011 | β |
| Dizziness and the genetic influences on subjective experiences to initial cigarette use. | Haberstick BC et al. | β | 2011 | β |
| GENES AS INSTRUMENTS FOR STUDYING RISK BEHAVIOR EFFECTS: AN APPLICATION TO MATERNAL SMOKING AND OROFACIAL CLEFTS. | Wehby G et al. | β | 2011 | β |
| Genetics of the association between intelligence and nicotine dependence: a study of male Swedish twins. | Modig K et al. | β | 2011 | β |
| Heritability of smoking, alcohol use, and psychological characteristics among adolescent twins in Qingdao, China. | Unger JB et al. | β | 2011 | β |
| Interplay between heritability of smoking and environmental conditions? A comparison of two birth cohorts. | Vink JM et al. | β | 2011 | β |
| Longitudinal effects of hostility, depression, and bullying on adolescent smoking initiation. | Weiss JW et al. | β | 2011 | β |
| Nicotine withdrawal-induced negative affect is a function of nicotine dependence and not liability to depression or anxiety. | Edwards AC et al. | β | 2011 | β |
| Smoking outcome expectancies in young adult female smokers: individual differences and associations with nicotine dependence in a genetically informative sample. | Kristjansson SD et al. | β | 2011 | β |
| Targeting nicotine addiction: the possibility of a therapeutic vaccine. | Escobar-ChΓ‘vez JJ et al. | β | 2011 | β |
| The galanin receptor 1 gene associates with tobacco craving in smokers seeking cessation treatment. | Lori A et al. | β | 2011 | β |
| Transdermal nortriptyline hydrocloride patch formulated within a chitosan matrix intended to be used for smoking cessation. | Escobar-ChΓ‘vez JJ et al. | β | 2011 | β |
| Association of a variant in the muscarinic acetylcholine receptor 2 gene (CHRM2) with nicotine addiction. | Mobascher A et al. | β | 2010 | β |
| Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population. | Li MD et al. | β | 2010 | β |
| Common and unique biological pathways associated with smoking initiation/progression, nicotine dependence, and smoking cessation. | Wang J et al. | β | 2010 | β |
| Genetically informative research on adolescent substance use: methods, findings, and challenges. | Lynskey MT et al. | β | 2010 | β |
| Marriage and Divorce: A genetic perspective. | Jerskey BA et al. | β | 2010 | β |
| Mechanisms underlying the lifetime co-occurrence of tobacco and cannabis use in adolescent and young adult twins. | Agrawal A et al. | β | 2010 | β |
| Pharmacogenetics of drug dependence: role of gene variations in susceptibility and treatment. | Khokhar JY et al. | β | 2010 | β |
| Pharmacogenetics of smoking cessation therapy. | Kortmann GL et al. | β | 2010 | β |
| Replicated association of the NR4A3 gene with smoking behaviour in schizophrenia and in bipolar disorder. | Novak G et al. | β | 2010 | β |
| Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the FagerstrΓΆm test for nicotine dependence. | Wessel J et al. | β | 2010 | β |
| A testable prognostic model of nicotine dependence. | Ramoni RB et al. | β | 2009 | β |
| Constitutional mechanisms of vulnerability and resilience to nicotine dependence. | Hiroi N et al. | β | 2009 | β |
| Dopamine genes and nicotine dependence in treatment-seeking and community smokers. | Bergen AW et al. | β | 2009 | β |
| Flexible Mx specification of various extended twin kinship designs. | Maes HH et al. | β | 2009 | β |
| Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample. | Hoft NR et al. | β | 2009 | β |
| Genome-wide and candidate gene association study of cigarette smoking behaviors. | Caporaso N et al. | β | 2009 | β |
| Genome-wide association study of smoking initiation and current smoking. | Vink JM et al. | β | 2009 | β |
| Influences of polymorphic variants of DRD2 and SLC6A3 genes, and their combinations on smoking in Polish population. | Sieminska A et al. | β | 2009 | β |
| Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes. | Saccone NL et al. | β | 2009 | β |
| Predictors of DSM and Fagerstrom-defined nicotine dependence in African American and Puerto Rican young adults. | Brook JS et al. | β | 2009 | β |
| Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking. | Berrettini W et al. | β | 2008 | β |
| Cannabinoid receptor 1 gene association with nicotine dependence. | Chen X et al. | β | 2008 | β |
| Do the same genetic and environmental effects underlie the covariation of alcohol dependence, smoking, and aggressive behaviour? | von der Pahlen B et al. | β | 2008 | β |
| Evidence for a two-stage model of dependence using the NESARC and its implications for genetic association studies. | Heiman GA et al. | β | 2008 | β |
| Five-Factor Model personality profiles of drug users. | Terracciano A et al. | β | 2008 | β |
| Gamma-aminobutyric acid receptor genes and nicotine dependence: evidence for association from a case-control study. | Agrawal A et al. | β | 2008 | β |
| Genetic and environmental contributions to nicotine, alcohol and cannabis dependence in male twins. | Xian H et al. | β | 2008 | β |
| Genetic association analysis of tagging SNPs in alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes (CHRNA4 and CHRNB2) with schizophrenia in the Japanese population. | Kishi T et al. | β | 2008 | β |
| Genetic factors contribute to the association between peers and young adults smoking: univariate and multivariate behavioral genetic analyses. | Harakeh Z et al. | β | 2008 | β |
| Genetics of nicotine dependence and pharmacotherapy. | Lessov-Schlaggar CN et al. | β | 2008 | β |
| Linkage of nicotine dependence and smoking behavior on 10q, 7q and 11p in twins with homogeneous genetic background. | Loukola A et al. | β | 2008 | β |
| Molecular genetics of successful smoking cessation: convergent genome-wide association study results. | Uhl GR et al. | β | 2008 | β |
| Psychiatric and familial predictors of transition times between smoking stages: results from an offspring-of-twins study. | Sartor CE et al. | β | 2008 | β |
| Association of functional catechol O-methyl transferase (COMT) Val108Met polymorphism with smoking severity and age of smoking initiation in Chinese male smokers. | Guo S et al. | β | 2007 | β |
| Evidence for specificity of transmission of alcohol and nicotine dependence in an offspring of twins design. | Volk HE et al. | β | 2007 | β |
| Exploring the inter-relationship of smoking age-at-onset, cigarette consumption and smoking persistence: genes or environment? | Morley KI et al. | β | 2007 | β |
| Exploring the relationship between genetic and environmental influences on initiation and progression of substance use. | Fowler T et al. | β | 2007 | β |
| Genes, time to first cigarette and nicotine dependence in a general population sample of young adults. | Haberstick BC et al. | β | 2007 | β |
| Lack of association of alcohol dependence and habitual smoking with catechol-O-methyltransferase. | Foroud T et al. | β | 2007 | β |
| Molecular genetics of nicotine dependence and abstinence: whole genome association using 520,000 SNPs. | Uhl GR et al. | β | 2007 | β |
| Non-nicotinic therapies for smoking cessation. | Siu EC et al. | β | 2007 | β |
| Overview of the pharmacogenomics of cigarette smoking. | Ho MK et al. | β | 2007 | β |
| RhoA, encoding a Rho GTPase, is associated with smoking initiation. | Chen X et al. | β | 2007 | β |
| The Nicotine Dependence Syndrome Scale in Finnish smokers. | Broms U et al. | β | 2007 | β |
| An association between the DAT1 polymorphism and smoking behavior in young adults from the National Longitudinal Study of Adolescent Health. | Timberlake DS et al. | β | 2006 | β |
| Association of the phosphatase and tensin homolog gene (PTEN) with smoking initiation and nicotine dependence. | Zhang L et al. | β | 2006 | β |
| Assortative mating for cigarette smoking and for alcohol consumption in female Australian twins and their spouses. | Agrawal A et al. | β | 2006 | β |
| Challenges in genetic studies of the etiology of substance use and substance use disorders: introduction to the special issue. | Prescott CA et al. | β | 2006 | β |
| Drugs and genotypes: how pharmacogenetic information could improve smoking cessation treatment. | Lee AM et al. | β | 2006 | β |
| Genetic architecture of smoking behavior: a study of Finnish adult twins. | Broms U et al. | β | 2006 | β |
| Intronic variants in the dopa decarboxylase (DDC) gene are associated with smoking behavior in European-Americans and African-Americans. | Yu Y et al. | β | 2006 | β |
| The implications of simultaneous smoking initiation for inferences about the genetics of smoking behavior from twin data. | Pergadia ML et al. | β | 2006 | β |
| The influence of genetics on nicotine dependence and the role of pharmacogenetics in treating the smoking habit. | Chatkin JM | β | 2006 | β |
| The mu-opioid receptor gene and smoking initiation and nicotine dependence. | Zhang L et al. | β | 2006 | β |
| A new childhood pathway for transmission of an increased likelihood of smoking? | Anthonisen N et al. | β | 2005 | β |
| Genetic influences on smoking: a brief review. | Al Koudsi N et al. | β | 2005 | β |
| Pathogenesis of lung cancer: 100 year report. | Miller YE | β | 2005 | β |