edgeR: a Bioconductor package for differential expression analysis of digital gene expression data.
paper
Cited
Public
- Authors
- Robinson, Mark D; McCarthy, Davis J; Smyth, Gordon K
- Year
- 2010
- Journal
- Bioinformatics (Oxford, England)
- PMID
- 19910308
- DOI
- 10.1093/bioinformatics/btp616
- PMCID
- PMC2796818
SUMMARY: It is expected that emerging digital gene expression (DGE) technologies will overtake microarray technologies in the near future for many functional genomics applications. One of the fundamental data analysis tasks, especially for gene expression studies, involves determining whether there is evidence that counts for a transcript or exon are significantly different across experimental conditions. edgeR is a Bioconductor software package for examining differential expression of replicated count data. An overdispersed Poisson model is used to account for both biological and technical variability. Empirical Bayes methods are used to moderate the degree of overdispersion across transcripts, improving the reliability of inference. The methodology can be used even with the most minimal levels of replication, provided at least one phenotype or experimental condition is replicated. The software may have other applications beyond sequencing data, such as proteome peptide count data. AVAILABILITY: The package is freely available under the LGPL licence from the Bioconductor web site (http://bioconductor.org).
DGE data can be visualized as βMAβ plots (log ratio versus abundance), just as with microarray data where each dot represents a gene. This plot shows RNA-seq gene expression for DHT-stimulated versus Control LNCaP cells, as described in Li et al. (2008). The smear of points on the left side signifies that genes were observed in only one group of replicate samples and the points marked βΓβ denote the top 500 differentially expressed genes.
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| Direct current electric field suppresses NPFFR2 expression in macrophages and alters its predicted conformational dynamics. | Zuo Z et al. | β | 2026 | β |
| Discovery of Ξ³-Tetrahydrocarboline Derivatives as <i>Plasmodium falciparum</i> Histone Deacetylase Inhibitors for Treatment of Malaria. | Ni H et al. | β | 2026 | β |
| Disease tolerance and infection pathogenesis age-related tradeoffs in mice. | Sanchez KK et al. | β | 2026 | β |
| Disrupting CDK9 activity suppresses triple-negative breast cancer and is enhanced by EGFR Inhibition. | van der Noord VE et al. | β | 2026 | β |
| Distinct Enterovirus Antigen Landscape in Children With Islet Autoimmunity. | Delgado-Corrales B et al. | β | 2026 | β |
| Distinct interneuronal dynamics selectively gate target-specific cortical projections in drug seeking. | Jeong M et al. | β | 2026 | β |
| Distinct molecular profiles characterize the spontaneous growth rate of IDHmt low-grade astrocytomas and oligodendrogliomas. | Darlix A et al. | β | 2026 | β |
| Distinct transcriptional programs control polyethylene glycol (PEG)-induced drought stress responses in oat (Avena sativa L.) shoot and roots. | Silva MSD et al. | β | 2026 | β |
| Divergent Transcriptional Architectures Beyond Core CAM Genes in Facultative and Constitutive CAM Species in Tillandsia L. | Groot-Crego C et al. | β | 2026 | β |
| Division of labor in trypanosome RNA processing and export through expanded Mex67 paralogs. | Obado SO et al. | β | 2026 | β |
| Dll4 assembles the umbilical cord and placental vasculature. | Sung DC et al. | β | 2026 | β |
| DNA methylation-mediated regulation of hypoxia-responsive genes facilitates high-altitude adaptation in Tibetan chickens. | Cao Y et al. | β | 2026 | β |
| DNA polymorphisms and N<sup>6</sup>-methyladenosine RNA methylation influencing microRNA expression and regulatory activity in plants. | Feng Z et al. | β | 2026 | β |
| Dominance and natural suppression of bacterial plant pathogens across global soils. | Gao M et al. | β | 2026 | β |
| Drug resistant cancer cells show increased nuclear mechanotransduction and mechanically targetable YAP-regulated vulnerability. | Huang M et al. | β | 2026 | β |
| Dual activity of low-molecular-weight polymeric Ξ²-cyclodextrins against tuberculosis. | Pochet A et al. | β | 2026 | β |
| Dual sigma receptor 1 and 2 modulator improves memory behavior in mouse model of age-related cognitive decline. | Loraine A et al. | β | 2026 | β |
| DUSP22 dephosphorylates LGALS1 to enhance T cell-driven antitumor immunity. | Wang L et al. | β | 2026 | β |
| Dynamic expression and functional analysis of circRNAs during albendazole resistance of Haemonchus contortus. | Chen X et al. | β | 2026 | β |
| Dysregulated immune microenvironment in metastatic colorectal cancer. | An S et al. | β | 2026 | β |
| Early Cd response and sequestration strategies in Arabidopsis halleri ssp. gemmifera elucidated by transcriptomic analysis. | Wiyono CDAP et al. | β | 2026 | β |
| Early detection of aberrant cell fate and repair using circulating progenitor cells in patients with heterotopic ossification. | Nunez J et al. | β | 2026 | β |
| Early gonadotoxic effects of cyclophosphamide on the prepubertal testis and the feasibility of reducing toxicity through combined antioxidant therapy. | Eskafinoghani A et al. | β | 2026 | β |
| EBV infection and HLA-DR15 jointly drive multiple sclerosis by myelin peptide presentation. | Wang J et al. | β | 2026 | β |
| Ectopic, but not endogenous, expression of the transcription factor gene MpSETA disrupts epidermal tissue formation in Marchantia polymorpha. | Moriya KC et al. | β | 2026 | β |
| Ectopic NMDAR expression in cancer unmasks germline-encoded autoimmunity. | Kleeman SO et al. | β | 2026 | β |
| Effects of extensive protein hydrolysate in supporting intestinal barrier function in vitro. | Bozzetti V et al. | β | 2026 | β |
| Effects of overexpression of the human intestinal alkaline phosphatase gene on the expression of related genes in intestinal epithelium-like cells. | Noda S et al. | β | 2026 | β |
| Effects of testosterone on gene expression in males and females across 40 human tissues. | Cheruiyot EK et al. | β | 2026 | β |
| Effects of urban PM2.5 on primary sinonasal epithelial cells in individuals with chronic rhinosinusitis. | Theorell J et al. | β | 2026 | β |
| Electroacupuncture repairs intestinal mucosal barrier in rats with diarrhea-predominant irritable bowel syndrome by regulating adherens junctions through mast cells and microRNAs. | Hou YJ et al. | β | 2026 | β |
| Elevated Tumor-Associated Androgen Receptor Activity Correlates with Poor Immune Infiltration and Immunotherapy Response across Cancer Types. | Hu YM et al. | β | 2026 | β |
| Elucidating pathway-selective biased CCKBR agonism for Alzheimer's disease treatment. | Wang JL et al. | β | 2026 | β |
| Emergence of high-metastatic potentials and prediction of recurrence and metastasis. | Srinivasan A et al. | β | 2026 | β |
| Endogenous 15(S)-hydroxyeicosatetraenoic acid mediates amplified estrogenic responses under nanoplastic-homosalate coexposure. | Li Z et al. | β | 2026 | β |
| Endogenous retroviruses synthesize heterologous chimeric RNAs to reinforce human early embryo development. | Xiang Y et al. | β | 2026 | β |
| Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol-Driven WNT7B Suppression. | Li X et al. | β | 2026 | β |
| Endosperm-specific overexpression of Opaque2 improves maize kernel texture. | Wu Z et al. | β | 2026 | β |
| Engineering FeoB-Mediated Iron Uptake Enhances Butyrate Fermentation in <i>Clostridium tyrobutyricum</i>. | Zeng Y et al. | β | 2026 | β |
| Engineering NK and T cells with metabolite-sensing receptors to target solid tumors. | Kim YM et al. | β | 2026 | β |
| Ensemble Machine Learning on Bulk RNA-Seq Identifies 17-Gene Signature Predicting Neoadjuvant Chemotherapy Response in Breast Cancer. | Lamprou S et al. | β | 2026 | β |
| Enterobacter sp. SA187 boosts high-affinity nitrate transporters expression, ethylene signaling, and plant growth under low nitrate. | Ilyas A et al. | β | 2026 | β |
| Environmental adaptation and functional diversity of calcin peptides from the venom of East Asian scorpions. | Hua X et al. | β | 2026 | β |
| Epigenetic and Transcriptional Programs Define Osteosarcoma Subtypes and Establish Targetable Vulnerabilities. | LΓ³pez-Fuentes E et al. | β | 2026 | β |
| Epigenomic aberrations of histone methylation in prefrontal cortex of humans with mild cognitive impairment and Alzheimer's disease. | Patel PJ et al. | β | 2026 | β |
| Epigenomic determinants of ferroptosis via oxidative stress in IPEC-J2 cells exposed to Ochratoxin A. | Ali S et al. | β | 2026 | β |
| Epigenomic subtypes of late-onset Alzheimer's disease reveal distinct microglial signatures. | Laroche VT et al. | β | 2026 | β |
| [ERI3 expression is elevated in hepatocellular carcinoma and correlates with poor patient prognosis]. | Zhao X et al. | β | 2026 | β |
| Erythropoietin receptor on cDC1s dictates immune tolerance. | Zhang X et al. | β | 2026 | β |
| Establishing the relationship between brain cellular senescence and brain structure. | Lund AN et al. | β | 2026 | β |
| Ethanol induces neuroimmune dysregulation and soluble TREM2 generation in a human iPSC neuron, astrocyte, microglia triculture model. | Boreland AJ et al. | β | 2026 | β |
| Eugenol Potentially Targets Oleate Delta-12 Desaturase of <i>Botrytis cinerea</i> and Controls Gray Mold as Part of a Combination of Multiple Fungicidal Components. | Wang X et al. | β | 2026 | β |
| Evaluating the Immunogenicity and Protective Efficacy of a Novel Vaccine Candidate Against <i>Salmonella</i> in Poultry. | Neelawala RN et al. | β | 2026 | β |
| Evaluation of statistical differential analysis methods for identification of senescent cells using single-cell transcriptomics. | Li D et al. | β | 2026 | β |
| Evidence of an allostatic response by intestinal tissues following induction of joint inflammation. | Moran MM et al. | β | 2026 | β |
| Evolutionary Divergence of an Ethylene-Responsive Transcriptional Cascade Governs a Dose-Dependent Balance between Cotton Fiber Length and Strength. | Zhang J et al. | β | 2026 | β |
| Evolutionary innovation within conserved gene regulatory networks underlying biomineralized skeletons in Bilateria. | Bai Y et al. | β | 2026 | β |
| Evolutionary transcriptomics unveils rapid changes of gene expression patterns in flowering plants. | Schuster C et al. | β | 2026 | β |
| Evolution of Highly Repetitive Silk Genes in the Luna Moth, Actias luna. | Foquet B et al. | β | 2026 | β |
| Exercise-related microRNAs in Caenorhabditis elegans regulate calcium homeostasis and mitochondrial dynamics: Conserved pathways, divergent microRNAs. | Xia Q et al. | β | 2026 | β |
| Exogenous amdoparvoviruses (Parvoviridae) in arvicoline voles: the molecular evolution and ecology of a novel host-viral association. | Jackson JA et al. | β | 2026 | β |
| Exogenous resources drive convergent successional processes within soil microbial food web in two soil types. | Cai YJ et al. | β | 2026 | β |
| Expansion of the geranylgeranyl pyrophosphate synthase gene family underlies the evolution of terpenoid biosynthesis in termites. | HorΓ‘Δek N et al. | β | 2026 | β |
| Exploring contributions and responses of microbial quantity and diversity to coastal seasonal hypoxia. | Li G et al. | β | 2026 | β |
| Exploring the Impact of DNA Methylation on Gene Expression in CRC: A Computational Approach for Identifying Epigenetically Regulated Genes in Multi-Omic Datasets. | Blindu AS et al. | β | 2026 | β |
| Exploring the possible cause of different levels of RNA silencing against BNYVV in transgenic sugar beets: a comparative virus transcriptome study. | Baghery MA et al. | β | 2026 | β |
| Exposure to a PFAS mixture alters cholesterol lipoprotein subfractions and induces a foam cell-like aortic macrophage expression profile in hyperlipidemic LDLr<sup>-/-</sup> mice. | Roth K et al. | β | 2026 | β |
| Exquisite specificity of Pks13 defines the essentiality of trehalose in mycobacteria. | Chen Y et al. | β | 2026 | β |
| Extinction of Nicotine and Cocaine Seeking in Rats Reveals Novel, Unique and Time-Dependent Molecular Adaptations in the Medial Prefrontal Cortex. | Muenstermann C et al. | β | 2026 | β |
| Extracellular vesicle microRNAs as an epigenetic biosignature of arsenic-associated diabetes in the Strong Heart Study. | Dye CK et al. | β | 2026 | β |
| Extracellular vesicles secreted by adipose-derived stem cells alleviate dedifferentiation and senescence in monolayer-expanded chondrocytes by suppressing interleukin-1Ξ²-induced MAPK signaling. | Wu SC et al. | β | 2026 | β |
| Facultative predation expands the ecological repertoire of <i>Streptomyces</i>. | Yamada K et al. | β | 2026 | β |
| Febrile temperature activates the innate immune response by promoting aberrant influenza A virus RNA synthesis. | Bisht K et al. | β | 2026 | β |
| FGF2 alters the calvarial suture niche homeostasis shifting skeletal stem cell/progenitors toward an osteo-angiogenic coupling fate. | Quarto N et al. | β | 2026 | β |
| Field pathogenomics and evolutionary conservation unveil CRISPR-targetable susceptibility genes for wheat blast resistance. | Khayer A et al. | β | 2026 | β |
| FLOWERING LOCUS T1 is a pleiotropic regulator of reproductive development, longevity, and source-sink relations in barley. | Helmsorig G et al. | β | 2026 | β |
| Foxp3 and BATF cooperatively direct cis-regulatory programs and gene expression for effector Treg cell differentiation. | Murakami R et al. | β | 2026 | β |
| FracFixR: a compositional statistical framework for absolute proportion estimation between fractions in RNA sequencing data. | Cleynen A et al. | β | 2026 | β |
| From omics to enhanced fungal virulence: overexpression of a putative secreted protein improves Beauveria bassiana biocontrol potential against the insect pest Piezodorus guildinii. | Oberti H et al. | β | 2026 | β |
| Fulvic acids act as chemical eustressors driving redox and hormonal reprogramming in rice roots. | van Tol de Castro TA et al. | β | 2026 | β |
| Functional genomic analysis of non-canonical DNA regulatory elements of the aryl hydrocarbon receptor. | Shahriar S et al. | β | 2026 | β |
| Further insights into the sialome switch of Amblyomma americanum adult females. | Lu S et al. | β | 2026 | β |
| Gain and loss of gene function shaped the nickel hyperaccumulation trait in Noccaea caerulescens. | Belloeil C et al. | β | 2026 | β |
| Gene expression links consistent immune and inflammatory pathways to bovine respiratory disease in high-risk stocker cattle. | Prosser HM et al. | β | 2026 | β |
| Gene expression profiling of the carbon pathways and virulence factors of Candida albicans in different carbon sources. | Lok B et al. | β | 2026 | β |
| Gene expression profiling to elucidate the promotive effects of the volatile organic compound 3-octanone on the mycelial growth of Ganoderma lucidum. | Horikawa S et al. | β | 2026 | β |
| Gene expression signatures of shortened-telomere-associated fibrotic interstitial lung disease. | Naso JR et al. | β | 2026 | β |
| Gene regulation in response to host sex and infection route in Brugia pahangi with new genome annotation. | Holt CI et al. | β | 2026 | β |
| Genetic Basis of UV Bullseye Size Variations in Turnip Rape (Brassica rapa subsp. oleifera). | Zhou ZL et al. | β | 2026 | β |
| Genetic loss of CHD1 regulates distinct histone post-translational modifications in the development of castration-resistant prostate cancer. | Purohit TA et al. | β | 2026 | β |
| Genetic variation shapes the chromatin accessibility landscape and transcriptional responses in mouse adipose tissue. | Mononen J et al. | β | 2026 | β |
| Genome- and Transcriptome-Wide Characterization of AP2/ERF Transcription Factor Superfamily Reveals Their Relevance in <i>Stylosanthes scabra</i> Vogel Under Water Deficit Stress. | Nunes CCCG et al. | β | 2026 | β |
| Genomes of Wiebesia Fig Wasps Reveal the Adaptation and Codiversification in the Fig-Fig Wasp Mutualism. | Lo BW et al. | β | 2026 | β |
| Genome-wide analysis of fifteen flavonoid biosynthesis gene families in moso bamboo (Phyllostachys edulis) and functional characterization of PeFNSI1 in modulating salicylic acid metabolic flux. | Wang J et al. | β | 2026 | β |
| Genome-wide analysis of flax bZIP genes using a T2T genome reveals abiotic stress roles. | Wang H et al. | β | 2026 | β |
| Genome-wide characterization and transcriptional profiling of the glycerol-3-phosphate acyltransferase (GPAT) family in barley reveals the role of HvGPAT1 in low nitrogen tolerance. | Quan X et al. | β | 2026 | β |
| Genome wide responses of the water flea, Daphnia carinata, to 6PPD and its oxidation product 6PPD-quinone. | Kumar A et al. | β | 2026 | β |
| Genome-wide transcriptome analysis reveals transcription factors associated with isoflavone content in soybean. | Wang J et al. | β | 2026 | β |
| Genomic consequences of domestication and the diversification of body coloration and morphology in ornamental medaka strains. | Kon T et al. | β | 2026 | β |
| Genomic Exaptation and Regulatory Landscape Shifts as Key Mechanisms Enabling Flatworm Terrestrialization. | Carbonetto B et al. | β | 2026 | β |
| Genomic Landscape Analysis of Canine Pulmonary Adenocarcinoma Reveals Candidate Targetable Gene Fusions. | Sakthikumar S et al. | β | 2026 | β |
| Genomic profiling reveals molecular heterogeneity in patients with Richter transformation (RT) and chronic lymphocytic leukemia (CLL). | Tian S et al. | β | 2026 | β |
| Genomic signatures in <i>Variovorax</i> enabling colonization of the <i>Populus</i> endosphere. | Beals DG et al. | β | 2026 | β |
| Genomic Variation and GWAS Analysis for Salt Tolerance Discovered in Egyptian Rice Germplasm. | Wang Y et al. | β | 2026 | β |
| Global loss of metabolic responsiveness and elevated enzyme in leptin deficient obese mice during starvation. | Li D et al. | β | 2026 | β |
| Glucocorticoid-dependence and independence of the circadian liver transcriptome. | Maidstone RJ et al. | β | 2026 | β |
| GLYATL1 is associated with metabolic and epigenetic changes and with endocrine resistance in luminal breast cancer. | MΓΌller J et al. | β | 2026 | β |
| Grapevines Pretreated with Biocontrol Bacteria Have an Altered Transcriptional Response to <i>Xylella fastidiosa</i> and a Reduction in Pierce's Disease Severity. | Deyett E et al. | β | 2026 | β |
| Gut Commensal Klebsiella pneumoniae Extracellular Vesicles Shape a Liver Microenvironment Conducive to Gut-Liver Bacterial Translocation and Pro-Tumorigenic Processes. | Tsubaki S et al. | β | 2026 | β |
| Gut microbial extracellular vesicles modulate the development of metabolic dysfunction-associated steatohepatitis through the gut-liver axis. | Kwak MJ et al. | β | 2026 | β |
| Gut microbial modulation of 3-hydroxyanthranilic acid and dopaminergic signalling influences attention in obesity. | Castells-Nobau A et al. | β | 2026 | β |
| Gut microbiota modulation of regulatory DNA elements revealed by massively parallel functional characterization. | Zaratiana C et al. | β | 2026 | β |
| H3K27me3 epigenetic mark crucial for Arabidopsis callus cellular identity and regeneration capacity. | Mandel T et al. | β | 2026 | β |
| H3K36 methyltransferase SDG102 enhances salt tolerance by altering the methylation level of genes in maize (Zea mays L.). | Liu X et al. | β | 2026 | β |
| H3K9 acetylation-NF-ΞΊB-AP-1 nexus targeted by ITE limits TNF-Ξ±-induced MMP-9 expression in monocytic cells. | Bahman F et al. | β | 2026 | β |
| Held out wings RNA binding activity in the cytoplasm during early spermatogenesis. | Agapiou M et al. | β | 2026 | β |
| Heme limitation induces LHR2, an essential gene for Leishmania pathogenesis. | Juez-Castillo G et al. | β | 2026 | β |
| Heterochromatin epimutations impose mitochondrial dysfunction to confer antifungal resistance. | Fellas A et al. | β | 2026 | β |
| Heterogeneity and plasticity of the naive CD4<sup>+</sup> T cell compartment. | Sajani A et al. | β | 2026 | β |
| High-CD14-expressing urothelial cancer cells foster a neutrophil-rich tumor microenvironment that increases the risk of radiation-promoted distant metastasis. | Chiang Y et al. | β | 2026 | β |
| High-content CRISPR activation screens identify synthetically lethal RNA-based mechanisms to sensitize cancer cells to targeted T cell cytotoxicity. | Akana RV et al. | β | 2026 | β |
| High-Resolution Genomic Resources for Trait Mapping and Precision Breeding for Adzuki Bean (Vigna angularis). | Hu L et al. | β | 2026 | β |
| High resolution multi-scale profiling of embryonic germ cell-like cell derivation reveals pluripotent state transitions in humans. | Stucchi S et al. | β | 2026 | β |
| High-throughput analyses of <i>Phocaeicola vulgatus</i> reveal fitness determinants for gut colonization and during colitis. | Elmekki NM et al. | β | 2026 | β |
| Histone lactylation bridges metabolic reprogramming with chromatin-immune crosstalk in triple-negative breast cancer. | Li J et al. | β | 2026 | β |
| Histone variant H2BE controls activity-dependent gene expression and homeostatic scaling. | Feierman ER et al. | β | 2026 | β |
| HIV-seq reveals gene expression differences between HIV-transcribing cells from viremic and suppressed people with HIV. | Frouard J et al. | β | 2026 | β |
| HIV transgenic mouse monocytes display increased <i>in vivo</i> migration across the blood-brain barrier associated with increased expression of genes associated with mononuclear leukocyte movement. | Sydenstricker A et al. | β | 2026 | β |
| Homeodomain protein Sxi1Ξ± independently controls cell-cell fusion and gene expression during sexual reproduction in Cryptococcus deneoformans. | Huang J et al. | β | 2026 | β |
| Homeostatic mature dendritic cells instruct fibroblast specialization via Notch2 signaling to establish T cell niches. | Alouche N et al. | β | 2026 | β |
| Hookworm genes encoding intestinal excreted-secreted proteins are transcriptionally upregulated in response to the host's immune system. | Schwarz EM et al. | β | 2026 | β |
| Host adaptation and genome evolution of the broad host range fungal rust pathogen, Austropuccinia psidii. | Luo Z et al. | β | 2026 | β |
| Host-mediated endophyte-pathogen competition in roots enables asymptomatic fungal colonization in Arabidopsis thaliana. | Hiruma K et al. | β | 2026 | β |
| Human body temperature cues widespread changes in virulence gene expression in uropathogenic <i>Escherichia coli</i>. | Dehner CA et al. | β | 2026 | β |
| Human clearance systems have a layered architecture across tissues and cell types that supports varied proteome compositions. | Vinogradov-Talyah E et al. | β | 2026 | β |
| Human fetal circulating factors from pregnancies complicated by obesity upregulate genes associated with pathological hypertrophy in neonatal rat cardiomyocytes. | Vaughan OR et al. | β | 2026 | β |
| Human gastric multi-regional assembloids for functional parietal maturation and patient-specific modelling of antral foveolar hyperplasia. | Jones BC et al. | β | 2026 | β |
| Human Hearts Intrinsically Increase Cardiomyocyte Mitosis After Myocardial Infarction. | Hume RD et al. | β | 2026 | β |
| Human hippocampal neurogenesis in adulthood, ageing and Alzheimer's disease. | Disouky A et al. | β | 2026 | β |
| Human iPSC-based Modeling of Pulmonary Fibrosis Reveals p300/CBP Inhibition Suppresses Alveolar Transitional Cell State. | Tsutsui Y et al. | β | 2026 | β |
| Human-specific lncRNAs contributed critically to human evolution by distinctly regulating gene expression. | Lin J et al. | β | 2026 | β |
| Humidity shapes reproductive development in Arabidopsis thaliana by modulating epidermal identity and cell wall dynamics. | Jeon WT et al. | β | 2026 | β |
| Hypertension-induced neurovascular and cognitive dysfunction at single-cell resolution. | Schaeffer SM et al. | β | 2026 | β |
| Hypothalamic deiodinase type-3 establishes the period of circannual interval timing in mammals. | Stewart C et al. | β | 2026 | β |
| ICE: robust detection of cellular senescence from weak single-cell signatures using imputation-based marker refinement. | Xu P et al. | β | 2026 | β |
| ICMT deficiency ameliorates weight loss and mortality, but not tumor formation in a mouse model of liver cancer. | Czarnota P et al. | β | 2026 | β |
| Identification and analysis of miRNA-mRNA regulatory networks of ZM-4 (Malus zumi) in response to salt stress. | Liu Z et al. | β | 2026 | β |
| Identification and Sequence Characterization of Semi-extractable RNAs. | Zeng C et al. | β | 2026 | β |
| Identification of 2 Ubiquitin-Proteasome System-Related Subtypes in Esophageal Squamous Cell Carcinoma for Prognostic and Immunotherapeutic Response Prediction. | Jiang C et al. | β | 2026 | β |
| Identification of a neoplastic Tfh-like cellular subset in a mouse model of angioimmunoblastic T cell lymphoma. | Mohammaei S et al. | β | 2026 | β |
| Identification of differentially expressed genes in RNA-seq data via semi-rigid orthogonal sparse KL-NMTF. | Gargano G et al. | β | 2026 | β |
| Identification of key miRNAs and target genes in psoriasis vulgaris and obesity co-morbidity. | Xu M et al. | β | 2026 | β |
| Identification of NLRP3 and TIPE2 as asthma biomarkers via integrative bioinformatics and Mendelian randomization. | Bao Y et al. | β | 2026 | β |
| Identifying candidate gut microbiota indicators for Alzheimer's disease through integrated data. | Wang J et al. | β | 2026 | β |
| IFNΞ³-induced memory in human macrophages is sustained by the durability of cytokine signaling itself. | Gorin A et al. | β | 2026 | β |
| <i>Megalomyrmex milenae</i> Transcriptome Reveals a Complex Venom Cocktail. | Sozanski KS et al. | β | 2026 | β |
| Immortalization and characterization of Schwann cell lines derived from NF1-associated cutaneous neurofibromas. | Li H et al. | β | 2026 | β |
| Immortalization of mesenchymal stromal cells by hTERT does not affect the functional properties of secreted extracellular vesicles. | Brancolini A et al. | β | 2026 | β |
| Immune-adaptive pathogen variation reveals targetable mediators of gram-positive bacterial killing in macrophages. | Russell CD et al. | β | 2026 | β |
| Immunometabolic determinants of long-term response in leukemia patients receiving CD19 CAR T cell therapy. | Goldberg L et al. | β | 2026 | β |
| Immuno-metabolic dysregulation in type 2 diabetes is associated with altered neutrophil functional plasticity, mitochondrial dysfunction, and compromised responses in sepsis. | Ganesh K et al. | β | 2026 | β |
| Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure. | Shearer JJ et al. | β | 2026 | β |
| Impact of heat stress on the miRNA cargo of pre-ovulatory follicular fluid extracellular vesicles and fertility in dairy cattle. | Kosior MA et al. | β | 2026 | β |
| Impact of low and high lipopolysaccharide doses on the early expression of immune related genes and transcription factors in chicken macrophage-like HD11 cells. | Jansseune SCG et al. | β | 2026 | β |
| Impaired cohesin loading disrupts pancreatic differentiation by Polycomb-driven chromatin rewiring and loop collapse. | Yu L et al. | β | 2026 | β |
| Impaired Complex I dysregulates neural/glial precursors and corpus callosum development revealing postnatal defects in Leigh syndrome mice. | Biswas SR et al. | β | 2026 | β |
| Incorporating genomic and transcriptomic effects in joint linear and non-linear structural models for predicting complex traits in pigs. | Vourlaki IT et al. | β | 2026 | β |
| Independent control of neurogenesis and dorsoventral patterning by NKX2-2. | Jang S et al. | β | 2026 | β |
| Indigenous gut microbes modulate neural cell state and neurodegenerative disease susceptibility. | Blackmer-Raynolds L et al. | β | 2026 | β |
| Induction of senescence during postpartum mammary gland involution supports tissue remodeling and promotes postpartum tumorigenesis. | Chiche A et al. | β | 2026 | β |
| Inflammatory Response to Menstrual Fluid Does Not Induce Fibrotic Morphogenesis Program in Human Endometrial Stromal Cells. | Eremichev R et al. | β | 2026 | β |
| Influence of Developmental Stage and Shading on Apple (<i>Malus domestica</i>) Flesh Polyphenols via Ecophysiological and Epigenetic Mechanisms. | Trompette E et al. | β | 2026 | β |
| INFO GRAB: An interactive shiny application for gene expression analysis and visualization. | Brown O et al. | β | 2026 | β |
| Ingestion of a human-relevant mixture of environmentally sourced microplastics promotes inflammation and tumorigenesis in the mouse colon. | Djouina M et al. | β | 2026 | β |
| Inhibiting L-type calcium channel promotes cardiomyocyte proliferation through activating the canonical Wnt signaling pathway. | Feng MY et al. | β | 2026 | β |
| Inhibition of Cxcr4 chemokine receptor signaling improves habituation learning in a zebrafish model of neurofibromatosis. | Miller AH et al. | β | 2026 | β |
| Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia. | Lewis AC et al. | β | 2026 | β |
| Inhibition of <i>Streptococcus</i> Biofilm Formation by 6'-Sialyllactose and <i>N</i>-Acetylneuraminic Acid. | Sato Y et al. | β | 2026 | β |
| Innate antiviral and immune functions associated with the HIV reservoir decay after anti-PD-1 therapy. | Talla A et al. | β | 2026 | β |
| Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression. | Xiao LM et al. | β | 2026 | β |
| Inositol hexaphosphate and inositol prevent WD/CClβ-induced metabolic dysfunction-associated steatohepatitis in mice. | Chen Z et al. | β | 2026 | β |
| Insights Into Sequences of Viral and Bacterial Origin in the Metatranscriptome of Centaurea cyanus L. Susceptible and Resistant to Acetolactate Synthase (ALS)-Inhibiting Herbicides. | Marcinkowska K et al. | β | 2026 | β |
| Insights into tea tree oil-mediated transcriptome modulation in Rosa hybrida. | Lopez-Jimenez J et al. | β | 2026 | β |
| Insights into the genetic bases of differential organ size in cacti flowers: a case study in two contrasting species. | Rosas-Reinhold I et al. | β | 2026 | β |
| Insulin resistance and SIK1 hyperactivation: implications for vascular remodeling in recurrent pregnancy loss. | Qi T et al. | β | 2026 | β |
| Integrated analysis of ATAC-seq and RNA-seq reveals the TCP-ARF molecular module related to pathogenic process of phytoplasma infection in Paulownia fortunei. | Huang S et al. | β | 2026 | β |
| Integrated analysis of DNA methylome and transcriptome of the backfat and longissimus dorsi muscle of Chinese-European hybrid pigs. | Ge M et al. | β | 2026 | β |
| Integrated Analysis of mRNA-seq and miRNA-seq Reveal the Dynamics of the Gonadal Differentiation of Procypris Mera. | Ke Z et al. | β | 2026 | β |
| Integrated analysis of the miRNA-mRNA regulatory network and role of the miRNA 1971-x in poly-Ξ²-hydroxybutyrate (PHB) immunoenhancement in gibel carp (Carassius auratus gibelio). | Zhang M et al. | β | 2026 | β |
| Integrated assessment of the effects of PFOA exposure on hepatic transcriptome and lipid profiles in mice expressing human PPARΞ±. | Nielsen G et al. | β | 2026 | β |
| Integrated bioinformatics and experimental validation identify FOXQ1, GRIN2D, and SCNN1B as novel biomarkers for distinguishing high-risk sessile serrated lesions from hyperplastic polyps. | Fatemi N et al. | β | 2026 | β |
| Integrated metabolomic and transcriptomic analyses elucidates the molecular mechanisms underlying cucurbitacin accumulation and bitterness development in Luffa fruits. | Zhu D et al. | β | 2026 | β |
| Integrated transcriptome analysis of jejunum and liver to identify key genes and pathways associated with body weight in chickens. | Abdel-Kafy EM et al. | β | 2026 | β |
| Integrated transcriptomic, translatomic, and physiological analyses reveal molecular mechanisms of chromium stress response in Chlamydomonas reinhardtii. | Zhang B et al. | β | 2026 | β |
| Integrative analysis of Poly(A)-seq and RNA-seq reveals transcriptional regulation of poly(A) tail length in tuberculosis. | Tuohetaerbaike B et al. | β | 2026 | β |
| Integrative analysis of quantitative trait loci of alternative polyadenylation and GWAS highlights key regulators of milk production and immune traits in Holstein. | Tao X et al. | β | 2026 | β |
| Integrative analysis of transcriptomics and gut microbiome in grass carp under alkalinity stress. | Guo J et al. | β | 2026 | β |
| Integrative analysis of urinary microRNAs for prostate cancer detection: A proof-of-concept study. | Samani LA et al. | β | 2026 | β |
| Integrative Application of Transcriptomics and Metabolomics Reveals Molecular Insight into Metabolomic Variations in Chinese Mitten Crab <i>Eriocheir sinensis</i> Harvested from Lake Datong and Adjacent Pond. | Lin L et al. | β | 2026 | β |
| Integrative assessment of sulfoxaflor effects on gene expression, reproduction, and behavior in the bumblebee Bombus impatiens. | Catto MA et al. | β | 2026 | β |
| Integrative methylation profiling uncovers IL10RB hypomethylation as a mediator between environmental heavy metal exposure and lung cancer risk. | Shin H et al. | β | 2026 | β |
| Integrative multi-omics defines melanoma drug response networks and ARID1A-dependent resistance mechanisms. | Barker CG et al. | β | 2026 | β |
| Integrative pan-resistome and transcriptomic characterization reveals differential gene expression signatures in carbapenem-resistant Acinetobacter baumannii: Insights into efflux pump regulation and therapeutic targeting strategies. | Gopikrishnan M et al. | β | 2026 | β |
| Integrative profiling of transcriptome and H3K27ac modification reveals changes associated with BCG-induced trained immunity in bovine immune cells. | Samuel BER et al. | β | 2026 | β |
| Integrative transcriptomic and functional analyses reveal candidate transcription factors associated with sorghum grain quality. | SΓ©ne M et al. | β | 2026 | β |
| Integrative transcriptomic meta-analysis reveals immune, synaptic, and non-coding RNA dysregulation in bipolar disorder across brain and blood. | Panina A et al. | β | 2026 | β |
| Integrative transcriptomics and electrophysiological profiling of hiPSC-derived neurons identifies novel druggable pathways in Koolen-de Vries Syndrome. | Verboven AHA et al. | β | 2026 | β |
| Intestinal interoceptive dysfunction drives age-associated cognitive decline. | Cox TO et al. | β | 2026 | β |
| Introducing furanocoumarin biosynthetic genes in tomato results in coumarins accumulation and impacts growth. | BouillΓ© A et al. | β | 2026 | β |
| Investigating cycle-to-cycle variation and the impact of endometrial injury through differential gene expression analysis. | Teh WT et al. | β | 2026 | β |
| Investigating the Response Mechanism of Weeping Forsythia to Stem Rot Caused by <i>Phomopsis velata</i> Using Transcriptomics. | He Y et al. | β | 2026 | β |
| In Vivo Chemical Reprogramming Is Associated With a Toxic Accumulation of Lipid Droplets Hindering Rejuvenation. | Mitchell W et al. | β | 2026 | β |
| In vivo endosomal escape assay identifies mechanisms for efficient hepatic LNP delivery. | JoziΔ A et al. | β | 2026 | β |
| In vivo exposure of mixed microplastic particles in mice and its impacts on the murine gut microbiome and metabolome. | Kim KJ et al. | β | 2026 | β |
| IPTG- and estradiol-inducible gene expression systems in the unicellular red alga Cyanidioschyzon merolae. | Fujiwara T et al. | β | 2026 | β |
| Isobaric quantitative proteomics reveals altered extracellular matrix, cytoskeletal, and degradation pathways in glaucomatous trabecular meshwork cells. | Holden P et al. | β | 2026 | β |
| isoespy: an integrated long-read transcriptome workflow for isoform resolution and visualization. | Ikemoto K et al. | β | 2026 | β |
| Jasmonate and salicylate signaling in rice defense against brown planthopper nymphs. | Kong Y et al. | β | 2026 | β |
| JMJD2 regulates enhancer-promoter interactions via biomolecular condensate formation. | Jiang S et al. | β | 2026 | β |
| Ketogenic diet dampens excitatory neurotransmission by shrinking synaptic vesicle pools. | Stunault MI et al. | β | 2026 | β |
| Kidney Volume and Molecular Processes are Dynamic in ADPKD. | Tug A et al. | β | 2026 | β |
| Knockdown of the fly spliceosome component Rbp1 (orthologue of SRSF1) extends lifespan. | Hayman DJ et al. | β | 2026 | β |
| Lack of MDA5 delays hematopoietic aging by modulating inflammaging and proteostasis in mice. | Bergo V et al. | β | 2026 | β |
| Lactate and histone H3K18 lactylation are associated with metabolic control of gene expression in the retina. | Gaur M et al. | β | 2026 | β |
| Large-scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of Ξ±Synuclein aggregation. | Neupane S et al. | β | 2026 | β |
| Large-scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome. | Borodovich T et al. | β | 2026 | β |
| Large-scale drug screening in iPSC-derived motor neurons from sporadic ALS patients identifies a potential combinatorial therapy. | Bye CR et al. | β | 2026 | β |
| LDHA as a Potential Therapeutic Target for Lactylation Regulation in Spinal Cord Injury: Integrated Bioinformatics Analysis, Experimental Validation, and Drug Prediction. | Zhang B et al. | β | 2026 | β |
| Lesion-remote astrocytes govern microglia-mediated white matter repair. | McCallum S et al. | β | 2026 | β |
| Leveraging low-cost short-read sequencing: revolutionizing complex trait genetics. | Ruckman SN et al. | β | 2026 | β |
| Life History and Smoltification Shape Genomic Signatures of Thermal Tolerance in Chinook Salmon. | Metzger DCH et al. | β | 2026 | β |
| Light stress regulates pigment concentrations, growth, and gene expression in hatchery-cultivated Kappaphycus alvarezii (Solieriaceae, Rhodophyta). | Tabonda-Nabor AM et al. | β | 2026 | β |
| LINC01929 mediates breast cancer immunosuppression and is an immunotherapy target. | Venkatesh J et al. | β | 2026 | β |
| Lineage-specific expansion and functional divergence of Ξ²-keratin genes underlying shell evolution in turtles. | Chen M et al. | β | 2026 | β |
| Lipoprotein(a) and Vascular Redox State in Patients With Advanced Coronary Atherosclerosis. | Polkinghorne MD et al. | β | 2026 | β |
| Liver metastases dampen IL18-driven Ξ³Ξ΄ T cell activity and immunotherapy responsiveness in colorectal cancer. | van Renterghem AWJ et al. | β | 2026 | β |
| LncRNA-splicing factor condensates regulate hypoxia-responsive pre-mRNA processing near nuclear speckles. | Song YJ et al. | β | 2026 | β |
| Lobe-Less, a Long Noncoding RNA That Regulates Drosophila Mushroom Body Morphogenesis. | Inagaki S et al. | β | 2026 | β |
| Longitudinal Peripheral Blood Transcriptomics Reveal Novel Signatures During Cardiac Allograft Rejection. | Ghazal R et al. | β | 2026 | β |
| Long non-coding RNA RP11-196G11.6 inhibits neuroblastoma progression by regulating the miR-376a-3p/RYBP signaling axis. | Zhang J et al. | β | 2026 | β |
| Long non-coding RNA UCA1 modulates SMARCA2-containing SWI/SNF chromatin remodeling complexes in human colorectal cancer. | Neve B et al. | β | 2026 | β |
| Loss of FAT1 drives cyclophosphamide resistance in breast cancer via the Wnt/Ξ²-Catenin pathway. | Zhong L et al. | β | 2026 | β |
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| <i>Fusarium oxysporum</i> f. sp. cubense Race 4 Effector, Foc4-305, Targets a Proline-Rich Protein in Banana and Contributes to Virulence. | You L et al. | β | 2026 | β |
| <i>In situ</i> transplantation and multiple omics reveal holobiont adaptation in deep-sea mussel <i>Gigantidas haimaensis</i>. | Wei T et al. | β | 2026 | β |
| <i>In vitro</i> polarized macrophages ameliorate adverse cardiac remodeling in a mouse model of transverse aortic constriction. | Yakhshimurodov U et al. | β | 2026 | β |
| <i>VILMIR</i> is a <i>trans</i>-acting long noncoding RNA that enhances the host interferon response in human epithelial cells. | John K et al. | β | 2026 | β |
| Lysine potentiates insulin secretion via AASS-dependent catabolism and regulation of GABA content and signaling. | MuΓ±oz F et al. | β | 2026 | β |
| MaAsLin 3: refining and extending generalized multivariable linear models for meta-omic association discovery. | Nickols WA et al. | β | 2026 | β |
| Macrophage retrotransposon expression is associated with lupus. | Zhong J et al. | β | 2026 | β |
| Male obesity causes adipose mitochondrial dysfunction in F<sub>1</sub> mouse progeny via a let-7-DICER axis. | Huang C et al. | β | 2026 | β |
| Manipulation of Alternative Splicing of <i>IKZF1</i> Elicits Distinct Gene Regulatory Responses in T Cells. | Pastor L et al. | β | 2026 | β |
| Mapping biology in space: from spatial transcriptomics platforms to analytical tools and databases. | Guo ZZ et al. | β | 2026 | β |
| Mast-cell derived nerve growth factor drives ILC2 pro-tumoral functions in bladder cancer. | Falquet M et al. | β | 2026 | β |
| Mechanical Stretch Disrupts Calcium Dynamics and Redistributes Piezo1 in Human Astrocytes. | Shiravi S et al. | β | 2026 | β |
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| Mechanisms of PfDNMT2 inhibition and PfATP6-mediated resistance to the antimalarial candidate SC83288 in Plasmodium falciparum. | Sanchez CP et al. | β | 2026 | β |
| Mediterranean Versus Western Diet Effects on Obesity Phenotypes and Adipose Tissue Transcriptional Profiles in Female Monkeys. | Abusheikha AJ et al. | β | 2026 | β |
| Melatonin attenuates mitochondrial apoptosis and improves mitochondrial quality by activating the AKT/BAD/BCL-XL signaling pathway, promoting oxidative muscle fiber formation. | Song P et al. | β | 2026 | β |
| Mesenchymal stromal cell therapy restores intestinal integrity and attentuates inflammation in a preterm piglet model of necrotizing enterocolitis. | Lee J et al. | β | 2026 | β |
| Metabolic coupling of arsenic, carbon, nitrogen, sulfur and iron in high-salinity groundwater in the Yellow River Delta: Insights from metagenomic analyses. | Zhi C et al. | β | 2026 | β |
| Metabolic engineering of doxorubicin biosynthesis through P450-redox partner optimization and structural analysis of DoxA. | Koroleva A et al. | β | 2026 | β |
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| Metabolic reprogramming regulates histone lactylation during zebrafish caudal fin regeneration. | Borbinha J et al. | β | 2026 | β |
| Metabolome and Transcriptome Profiling of Chicory Roots Provide Insights Into Laticifer Development and Specialized Metabolism. | Vahabi K et al. | β | 2026 | β |
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| Metatranscriptomic analysis of Anopheles species from Menoreh Hills endemic area in Central Java, Indonesia. | Nuranindita R et al. | β | 2026 | β |
| Metformin inhibits nuclear egress of chromatin fragments in senescence and aging. | Kumazawa T et al. | β | 2026 | β |
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| Microbiome by transcriptome interactions triggered by a switch to an alternative diet in Nellore cattle. | Fernandes AC et al. | β | 2026 | β |
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| Multiomic, Histologic, and scRNA-seq Profiling of Pleural Mesothelioma Reveals Negative Prognosis Associated With a Novel Uncommitted Molecular Phenotype. | Severson DT et al. | β | 2026 | β |
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| Plasma extracellular vesicle sampling from glioblastoma demonstrates a small RNA signature indicative of disease and identifies lncRNA <i>RPPH1</i> as a biomarker. | Ho Han J et al. | β | 2026 | β |
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| Reprogramming SREBP1-dependent lipogenesis and inflammation in high-risk breast with licochalcone A: A novel path to cancer prevention. | Hajirahimkhan A et al. | β | 2026 | β |
| Residual Breast Cancer Cells Co-opt SOX5-Driven Endochondral Ossification to Maintain Dormancy. | Sreekumar A et al. | β | 2026 | β |
| Resistance of BRAF<sup>V600E</sup>-mutant melanoma to Vemurafenib: a senescence-induced swing from differentiation to blastulation followed by proliferation. | Rumnieks F et al. | β | 2026 | β |
| Retinol dehydrogenase 10-mediated retinoic acid signaling regulates the neural crest cell microenvironment during enteric nervous system formation. | Butler Tjaden NE et al. | β | 2026 | β |
| Revelation of metabolic pathways and potential targets associated with latent and active pulmonary tuberculosis via transcriptome and metabonomics analysis. | Zhou Y et al. | β | 2026 | β |
| Rhapontigenin alleviates cellular senescence and physiological aging by upregulating sirt1 and promoting autophagy. | Liu S et al. | β | 2026 | β |
| Rhizoid-mediated phosphate uptake and internal transport in the non-vascular plant Marchantia polymorpha. | Kanno S et al. | β | 2026 | β |
| RHOT Proteins Link Mitochondrial Motility to Cardiomyocyte Sarcomere Maturation. | Froese N et al. | β | 2026 | β |
| R-loop editing by DNA cytosine deaminase APOBEC3B modulates the activity of oestrogen receptor enhancers. | Zhang C et al. | β | 2026 | β |
| RNA-sequencing reveals ECM-remodeling and tumorigenesis in Pacific mackerel with Puffy Snout Syndrome. | Leidholt SL et al. | β | 2026 | β |
| Safety and activity of RO7300490, a bispecific CD40 agonist targeted to fibroblast activation protein, in patients with advanced solid tumors: a single-arm, multicenter, first-in-human, phase 1 trial. | Melero I et al. | β | 2026 | β |
| Salinomycin as a death switch: how gastric cancer cells choose their demise. | Laurenziello P et al. | β | 2026 | β |
| saseR: juggling offsets unlocks RNA-seq tools for fast and scalable differential usage, aberrant splicing and expression retrieval. | Segers A et al. | β | 2026 | β |
| scDBImpute: Dual-Branch Imputation for Single-Cell RNA-Seq Data Dropouts. | Zhang L et al. | β | 2026 | β |
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| Acute kidney injury following fatty liver ischemia-reperfusion injury: indirect protection by hepatic ferroptosis inhibition. | Zhang W et al. | β | 2025 | β |
| Addressing the mean-variance relationship in spatially resolved transcriptomics data with spoon. | Shah K et al. | β | 2025 | β |
| A deep metagenomic atlas of Qinghai-Xizang Plateau lakes reveals their microbial diversity and salinity adaptation mechanisms. | Zhang ZF et al. | β | 2025 | β |
| A defined bacterial consortium and spatial transcriptomics highlight the complex interaction between <i>Campylobacter jejuni</i> and the murine intestine. | Chitre S et al. | β | 2025 | β |
| Advancing leprosy risk prediction through identification of a whole blood host transcriptomic biomarker signature including non-coding genes. | Almeida MR et al. | β | 2025 | β |
| A genome-wide CRISPR screen identifies the TNRC18 gene locus as a regulator of inflammatory signaling. | Rahimov F et al. | β | 2025 | β |
| Agri-plastics in soils drive changes in the rhizosphere bacterial community and plant transcriptome in Arabidopsis. | Lee D et al. | β | 2025 | β |
| A high-quality genome assembly of angel-wing mushroom Pleurocybella porrigens that causes acute encephalopathy. | Watanabe N et al. | β | 2025 | β |
| AI-Integrated Omics Analysis Reveals Cultivar-Specific Resistance Mechanisms to Powdery Mildew in <i>Cucurbita pepo</i>. | Dublino R et al. | β | 2025 | β |
| Airway transcriptome networks for ozone and PM<sub>2.5</sub> exposure reveal distinct key drivers for children with asthma. | Chun Y et al. | β | 2025 | β |
| ALDH3A2 negatively orchestrates gastric cancer progression through a synergistic induction of ferroptosis and ferroptosis-driven macrophage reprogramming. | Ren Y et al. | β | 2025 | β |
| ALFQ adjuvanted HIV-1 envelope protein vaccination elicits durable functional antibody and cellular responses in nonhuman primates. | Shrivastava S et al. | β | 2025 | β |
| A lipoxygenase gene modulates jasmonate biosynthesis to enhance blast resistance in rice. | Wang L et al. | β | 2025 | β |
| Altered Co-Expression Patterns of Mitochondrial NADH-Dehydrogenase Genes in the Prefrontal Cortex of Rodent ADHD Models. | Sylko PA et al. | β | 2025 | β |
| A molecular, spatial and regulatory atlas of the Hydra vulgaris nervous system. | Morris Little H et al. | β | 2025 | β |
| A multi-omic characterization of the physiological responses to salt stress in Scenedesmus obliquus UTEX393. | Kruse CPS et al. | β | 2025 | β |
| A Multipotent PROX1+ Tumor Stem/Progenitor Cell Population Emerges during Intestinal Tumorigenesis and Mediates Radioresistance in Colorectal Cancer. | Kallio P et al. | β | 2025 | β |
| A mutually antagonistic mechanism mediated by RNA m<sup>6</sup>A modification in plant-virus interactions. | Liu JH et al. | β | 2025 | β |
| An allele-resolved nanopore-guided tour of the human placental methylome. | Kindlova M et al. | β | 2025 | β |
| Analyses of contiguous reference genomes of Amaranthus tuberculatus highlight the landscape of the sex-associated region and PEBP gene family diversity. | Raiyemo DA et al. | β | 2025 | β |
| Analysing fungal microbiome differences between the roots of healthy and diseased Chinese hickory (Carya cathayensis) trees. | Su S et al. | β | 2025 | β |
| Analysis of a near telomere-to-telomere genome of Phellodendron amurense reveals insights into berberine biosynthesis. | Chen S et al. | β | 2025 | β |
| Analysis of Human Uniparental Embryonic Stem Cells Reveals New Putative Imprinted Loci. | Kinreich S et al. | β | 2025 | β |
| Analysis of microRNA-transcript regulatory networks in the hippocampus of the BTBR mouse model of autism. | Gasparini S et al. | β | 2025 | β |
| Analysis of the differential transcriptome expression profiles during prenatal muscle tissue development in Diqing Tibetan pigs. | Luo S et al. | β | 2025 | β |
| Androgen Receptors Promote Oxidative Phosphorylation and Resistance to Palmitate Lipotoxicity in ER-Mutant Breast Cancer. | Sessions DT et al. | β | 2025 | β |
| A new algorithm Precision OncoPanels (PrOPs) identifies short individualized actionable panels that can guide cancer treatment: a pan-cancer analysis of TCGA cohorts. | Sriraman S et al. | β | 2025 | β |
| An<i>in vitro</i>model of stiffened colonic mucosa exhibits altered epithelial behavior. | Massaro A et al. | β | 2025 | β |
| A non-canonical lymphoblast in refractory childhood T-cell leukaemia. | Lim BSJ et al. | β | 2025 | β |
| A novel GCGR/GLP-1R dual-agonist TB001 ameliorates kidney fibrosis via inhibiting PERK-mediated endoplasmic reticulum stress pathway. | Lai W et al. | β | 2025 | β |
| A novel role of BPCs in the control of medial domain differentiation during gynoecium development in Arabidopsis thaliana. | Caselli F et al. | β | 2025 | β |
| An ovine model shows that subcutaneous adipose tissue fibrosis occurs early in polycystic ovary syndrome (PCOS). | Wang Y et al. | β | 2025 | β |
| An RbohC and RbohE-mediated ROS oscillatory circuit regulates root cap turnover in Arabidopsis. | Shin YS et al. | β | 2025 | β |
| An RBPMS-driven splicing regulatory axis including MBNL1, RBFOX2, and QK promotes smooth muscle cell contractile identity. | Huang Y et al. | β | 2025 | β |
| Anti-Cancer Activity of <i>Sphaerococcus coronopifolius</i> Algal Extract: Hopes and Fears of a Possible Alternative Treatment for Canine Mast Cell Tumor. | Mucignat G et al. | β | 2025 | β |
| Antioxidant, antiaging and mitochondrial protective effects of JadeAging in <i>Caenorhabditis elegans</i>. | Lu B et al. | β | 2025 | β |
| Anti-U1-RNP antibody positivity is associated with elevated interferon-stimulated gene expression scores in systemic lupus erythematosus irrespective of disease activity: a transcriptome analysis in Japanese patients. | Matsui T et al. | β | 2025 | β |
| An unsupervised tool for biomarker discovery and cancer subtyping applied to glioblastoma. | Coletti R et al. | β | 2025 | β |
| AP-1 elements in the promoter and second intron mediate endoplasmic reticulum stress-induced expression of the GPAT3 gene. | Γrd D et al. | β | 2025 | β |
| Application of quercetin enhances tobacco resistance to Phytophthora nicotianae. | Duan Y et al. | β | 2025 | β |
| Approaches for identification of 5' UTR mutations impacting translation and protein production from neurodevelopmental disorder genes. | Plassmeyer SP et al. | β | 2025 | β |
| Arabidopsis LOHN1 peptide modulates lateral root spacing under the control of systemic nitrogen-satiety signaling. | Ito K et al. | β | 2025 | β |
| Artificial intelligence in gut microbiome research: Toward predictive diagnostics for neurodegenerative disorders. | Kumar R et al. | β | 2025 | β |
| A small periplasmic protein governs broad physiological adaptations in Vibrio cholerae via regulation of the DbfRS two-component system. | Nguyen E et al. | β | 2025 | β |
| ASPEN: Robust detection of allelic dynamics in single cell RNA-seq. | Petrova V et al. | β | 2025 | β |
| Assessment of antigen-specific T cell recall responses in non-human primates using a composite AIM assay. | Schmidt JM et al. | β | 2025 | β |
| Astragalin attenuates caerulein-induced acute pancreatitis by targeting the NLRP3 signaling pathway and gut microbiota. | Jia Y et al. | β | 2025 | β |
| A transcription termination mechanism for maintaining homogeneous protein expression. | Esteban-Serna S et al. | β | 2025 | β |
| A transcriptomic signature that predicts prehypertension in adolescence and higher systolic blood pressure in childhood. | Perchard R et al. | β | 2025 | β |
| A unified single-cell atlas of human lung provides insights into pulmonary diseases. | Wu F et al. | β | 2025 | β |
| Autism spectrum disorder risk genes have convergent effects on transcription and neuronal firing patterns in primary neurons. | Paranjapye A et al. | β | 2025 | β |
| Bacterial modification of the root cell wall facilitates rice aluminum resistance in acidic soils. | Zhang L et al. | β | 2025 | β |
| Base editing of Ξ²<sup>0</sup>-thalassemia mutations as a therapeutic strategy for severe Ξ²-hemoglobinopathies. | Hardouin G et al. | β | 2025 | β |
| Benzalkonium chloride accumulates and causes toxicity in the heart and pancreas following the repeated inhalation exposures. | Kim G et al. | β | 2025 | β |
| Bioenergetic reprogramming of macrophages reduces drug tolerance in Mycobacterium tuberculosis. | Yadav V et al. | β | 2025 | β |
| Blueberries Reduce Palm Oil-Induced Metabolic Endotoxemia in an In Vitro Human Intestinal-Immune Cell Model. | Casademont-Roca A et al. | β | 2025 | β |
| BMP4 cocktail promotes utricular progenitor reprogramming and vestibular functional recovery in adult mice. | You D et al. | β | 2025 | β |
| Bovine adipose mitochondrial adaptation and a potential lactate-ketone toggle in early lactation. | O'Boyle NJ et al. | β | 2025 | β |
| Brain-derived extracellular vesicles circUsp32 polarized macrophages causing acute kidney injury after traumatic brain injury. | Fu J et al. | β | 2025 | β |
| Bulk RNA sequencing dataset of Claudin-low breast cancer cell lines with Neuropilin-1 knockdown. | Lynam LR et al. | β | 2025 | β |
| C1orf50 Accelerates Epithelial-Mesenchymal Transition and the Cell Cycle of Hepatocellular Carcinoma. | Tanaka A et al. | β | 2025 | β |
| C1q drives neural stem cell quiescence by regulating cell cycle and metabolism through BAI1. | Piltti KM et al. | β | 2025 | β |
| Cancer-associated snaR-A noncoding RNA interacts with core splicing machinery and disrupts processing of mRNA subpopulations. | Zhou S et al. | β | 2025 | β |
| Candidate genes at the Rmi1 locus for resistance to Meloidogyne incognita in soybean. | Goode K et al. | β | 2025 | β |
| Cardiometabolic and molecular adaptations to 6-month intermittent fasting in middle-aged men and women with overweight: secondary outcomes of a randomized controlled trial. | Barve RA et al. | β | 2025 | β |
| CDK7 is a novel therapeutic target in fibrolamellar carcinoma. | Nukaya M et al. | β | 2025 | β |
| Cell line-matched reference enables high-precision functional genomics. | Corda L et al. | β | 2025 | β |
| Cell-surface RNA forms ternary complex with RNA-binding proteins and heparan sulfate to recruit immune receptors. | Li Z et al. | β | 2025 | β |
| Cetuximab-mediated antibody-dependent cell-mediated cytotoxicity enhances anti-tumor efficacy of patient-derived natural killer cells in pancreatic cancer. | Kim E et al. | β | 2025 | β |
| Characterization of Drug-Tolerant Persister Cells in Triple-Negative Breast Cancer Identifies a Shared Persistence Program across Treatments and Patients. | Baudre L et al. | β | 2025 | β |
| Chemotherapy-driven intestinal dysbiosis and indole-3-propionic acid rewire myelopoiesis to promote a metastasis-refractory state. | Bersier L et al. | β | 2025 | β |
| CHIP-seq and transcriptomics reveal a new role of circadian-regulated StBBX24 protein in potato reproduction. | GrΔ dzka K et al. | β | 2025 | β |
| Chromatin accessibility of circulating CD8βΊ T cells differentiates disease severity in IgA nephropathy. | Kim G et al. | β | 2025 | β |
| Chromatin and transcriptional dynamics underlying the immune-modulatory effects of vitamin D<sub>3</sub> in vivo. | RybiΕski M et al. | β | 2025 | β |
| Chromosome duplication causes premature aging via defects in ribosome quality control. | Escalante LE et al. | β | 2025 | β |
| Chromosome-level comparative genomics and host-specific fungal transcriptomics uncover adaptive virulence strategies in the sugarcane smut pathogen. | Vilanova PF et al. | β | 2025 | β |
| Chronic Intermittent Hypoxia Exposure Induces a Unique Microglial Transcriptome in 5XFAD Mice. | Marino KM et al. | β | 2025 | β |
| circRNA-associated-ceRNA networks in patients with traumatic tracheal stenosis. | Qin S et al. | β | 2025 | β |
| Community interactions drive phytoplankton regime shifts in interconnected water bodies: Insights from space for time approach. | Zhu Y et al. | β | 2025 | β |
| Comparative analyses of cucumber (Cucumis sativus L.) cultivars with varying node formation rate in greenhouse. | Ando E et al. | β | 2025 | β |
| Comparative Genomics Analysis Combined with Homologous Overexpression Reveals the Mechanism of Species-Specific Acid Stress Resistance in <i>Bifidobacterium animalis</i>. | Lin L et al. | β | 2025 | β |
| Comparative transcription profiles of <i>Candidatus</i> Accumulibacter and <i>Propionivibrio</i> under phosphate limitation in sequencing batch reactors. | Cardona L et al. | β | 2025 | β |
| Comparative transcriptome atlas as an assistive modality for complex classification of rare kidney cancers. | Jikuya R et al. | β | 2025 | β |
| Comparative transcriptome profiling of peripheral blood mononuclear cells suggests Protocadherin-1 (PCDH1) as a distinctive innate immunity signature in Sahiwal, Tharparkar and Gir compared to Karan Fries cattle. | Roshan M et al. | β | 2025 | β |
| Comparative Transcriptomic Analysis of Soybean Recombinant Inbred Lines Differing at the <i>Rmi1</i> Locus for Resistance to <i>Meloidogyne incognita</i> During Early Stages of Nematode Infection. | Goode K et al. | β | 2025 | β |
| Comparative Transcriptomics as a Key to Understanding the Adaptation Mechanisms of Baikal Sculpins to the Deep-Water Habitat. | Sapozhnikova YP et al. | β | 2025 | β |
| Comparing apoplastic root barrier formation and morphology in six crop species cultivated in soil vs. hydroponics. | Carvajal J et al. | β | 2025 | β |
| Comparison of Gastric Cancer Models Using Different Dimensions InΒ Vitro. | Zheng W et al. | β | 2025 | β |
| Compiling an early life human gut microbiome atlas and identification of key microbial drivers. | Tarracchini C et al. | β | 2025 | β |
| Comprehensive bulk and single-cell RNA sequencing uncovers senescence-associated biomarkers in therapeutic mesenchymal stem cells. | Pekker E et al. | β | 2025 | β |
| Comprehensive Transcriptomic Analysis and Experimental Validation of Notochordal Cells and Nucleus Pulposus Cells: Uncovering Novel Therapeutic Targets for Intervertebral Disc Degeneration. | Li Y et al. | β | 2025 | β |
| Comprehensive transcriptomic profiling reveals tissue-specific molecular signatures and dysregulated pathways in human diabetic foot ulcers. | Hu G et al. | β | 2025 | β |
| Computational Analyses and Challenges of Single-cell ATAC-seq. | Wang C et al. | β | 2025 | β |
| Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically diverse <i>Caenorhabditis</i> nematodes. | Banse SA et al. | β | 2025 | β |
| Conserved genetic markers reveal widespread diatom sexual reproduction in the global ocean. | Bilcke G et al. | β | 2025 | β |
| Conserved small RNA networks link inflammation to pain signaling in mice and men. | Madrer N et al. | β | 2025 | β |
| Cooperation between architectural C2H2 proteins in CP190 recruitment to Drosophila regulatory elements. | Maksimenko O et al. | β | 2025 | β |
| Coordinated Auxin-Cytokinin-Nitrogen Signaling Orchestrates Root Suckering in Populus. | Pang H et al. | β | 2025 | β |
| Coxsackie and adenovirus receptor is a novel regulator of inflammatory response in endotoxin-induced failing heart. | Matsumura R et al. | β | 2025 | β |
| Cross-tissue transcriptome-wide association identify novel T1D susceptibility genes and drug candidates. | Liu Y et al. | β | 2025 | β |
| Cultivar-specific preference of bacterial communities and host immune receptor kinase modulate the outcomes of rice-microbiota interactions. | Xu J et al. | β | 2025 | β |
| Cyclin A2 induces cytokinesis in human adult cardiomyocytes and drives reprogramming in mice. | Bouhamida E et al. | β | 2025 | β |
| Cytokine-Cytokine Receptor Interaction and Endocytosis are Common Pathways for Symptom Burden and Sickness Behavior Symptoms in Oncology Patients Undergoing Chemotherapy. | Harris CS et al. | β | 2025 | β |
| Cytokine supplementation influences bovine embryo transcriptome during the preimplantation period. | McDonald KS et al. | β | 2025 | β |
| Decaprenyl diphosphate synthases in Monolepta hieroglyphica: DPPS-mediated CoQ biosynthesis impacts juvenile hormone and gut microbiota. | Song X et al. | β | 2025 | β |
| Deciphering Conserved Rhizosphere Metabolite-Microbiome Interactions for Crop Drought Resistance. | Niu G et al. | β | 2025 | β |
| Deciphering drought-response in wheat (<i>Triticum aestivum</i>): physiological, biochemical, and transcriptomic insights into tolerant and sensitive cultivars under dehydration shock. | Cevher-Keskin B et al. | β | 2025 | β |
| Deciphering the biological underpinnings behind prognostic MRI-based imaging signatures in breast cancer: a systematic review. | Song N et al. | β | 2025 | β |
| Decoding cancer heterogeneity through super-enhancer landscapes: from subtype discovery to therapeutic opportunity. | Cai S et al. | β | 2025 | β |
| Decoding host immune response: circRNAs in Klebsiella variicola-infected chicken spleens. | Yin L et al. | β | 2025 | β |
| Deep learning-aided inter-species-comparison reveals shared and distinct molecular patterns in cynomolgus monkey and humans following non-specific T cell activation. | Friedrich VD et al. | β | 2025 | β |
| Deep proteogenomic characterization of pancreatic solid pseudopapillary neoplasm reveals unique features distinct from other pancreatic tumors. | Tanaka A et al. | β | 2025 | β |
| DEG-by-Index Ratio Transformation Normalization with Blood RNA-Seq Enhances Early and Consistent Detection of Mouse Tumorigenesis. | Shin SW et al. | β | 2025 | β |
| Delineating transcriptomic signatures of in vitro human skeletal muscle models in comparison to in vivo references. | Van Puyvelde M et al. | β | 2025 | β |
| Denoising single-cell RNA-seq data with a deep learning-embedded statistical framework. | Luo Q et al. | β | 2025 | β |
| Detection of differentially expressed genes in bantam chickens providing insights into chicken dwarfism. | Wu Z et al. | β | 2025 | β |
| Developmentally dynamic chromatin state at loci regulating organ crosstalk by remote sensing and signaling. | Parmar A et al. | β | 2025 | β |
| Dexamethasone enhances intestinal glucose absorption and TMPRSS2 expression with implications for hyperglycaemia and infection risk. | Visvanathan R et al. | β | 2025 | β |
| DGEAR: a web-based application for differential gene expression analysis and downstream functional insights. | Bardhan K et al. | β | 2025 | β |
| Diet modulates Vibrio cholerae colonization and competitive outcomes with the gut microbiota. | Liu R et al. | β | 2025 | β |
| Differential expression of genes in pre-blastoderm embryos of oriental fruit fly, Bactrocera dorsalis (Hendel) (Diptera: Tephritidae) microinjected with white locus CRISPR/Cas9 ribo nucleo protein (RNP) complex. | Ashok K et al. | β | 2025 | β |
| Differential gene expression and phenotypic variation across tissues between <i>Saccharum officinarum</i> and <i>Saccharum spontaneum</i>. | Wang QN et al. | β | 2025 | β |
| Differential gene expression in dromedary camels infested with sarcoptic mange. | Mehta SC et al. | β | 2025 | β |
| DiffHiChIP: Identifying differential chromatin contacts from HiChIP data. | Bhattacharyya S et al. | β | 2025 | β |
| Discovery and Development of a Small-Molecule Inhibitor Targeting the GAS41 YEATS Domain in Nonsmall Cell Lung Cancer. | Listunov D et al. | β | 2025 | β |
| Discovery of placental microRNAs associated with maternal insulin sensitivity during pregnancy. | Majid S et al. | β | 2025 | β |
| Distinct microRNA profiles in neuron-derived extracellular vesicles between recent-onset and chronic-phase schizophrenia. | Tomita Y et al. | β | 2025 | β |
| Distinct miRNA profiles in human amniotic tissue and its vesicular and non-vesicular secretome. | Chaves-Solano N et al. | β | 2025 | β |
| Distinct neuroprotective and anti-inflammatory effects of Kampo formulas ninjinyoeito and juzentaihoto in depression-like SAMP8 mice. | Maruko A et al. | β | 2025 | β |
| Distinct transcriptomic and epigenomic responses of mature oligodendrocytes during disease progression in a mouse model of multiple sclerosis. | Zheng C et al. | β | 2025 | β |
| Divergence between neural and retinal lineage specification during human brain development by signal transduction. | Nam KH et al. | β | 2025 | β |
| Divergent immune responses to commensal bacteria bearing distinct motility signatures. | Duck LW et al. | β | 2025 | β |
| DLBCL Cells Emerge after CD19 CAR T Cells with Cross-Antigen Resistance and a Gene Signature Predictive of Clinical CAR T-cell Response. | LΓΌΓΆnd F et al. | β | 2025 | β |
| DNA topoisomerase II promotes N<sup>6</sup>-adenosine mRNA methylation. | MegΓas-FernΓ‘ndez C et al. | β | 2025 | β |
| DNMT3B Knockdown Enhances PARP Inhibitor Sensitivity in Biliary Tract Cancer Cells via Opioid Growth Factor Receptor-Mediated Homologous Recombination Impairment. | Oda S et al. | β | 2025 | β |
| Dual impact of interleukin-17Β A blockade on inflammatory and stromal pathways in peripheral spondyloarthritis. | Hammoura I et al. | β | 2025 | β |
| Dual transcriptomic profiling of <i>Staphylococcus aureus</i> endocarditis in a porcine model reveals strong parallels with human infection. | GarcΓa B et al. | β | 2025 | β |
| During the Formation of Vasculogenic Mimicry by Melanoma Cells, the Silencing of Two Sets of Developmental Genes Is Coupled Either with an Increase or a Decrease in Contacts with the Nucleoli. | Tchurikov NA et al. | β | 2025 | β |
| Dynamic astrocytic complement C3 activation in the epileptic hippocampus. | Jiang M et al. | β | 2025 | β |
| Dynamic transcriptomic features accompanying the onset of first flowering in roses. | Wen J et al. | β | 2025 | β |
| Dysregulated circRNA-miRNA-mRNA networks reveal stage-specific mRNA expression changes in Parkinson's disease. | Gao Y et al. | β | 2025 | β |
| E7386 Enhances Lenvatinib's Antitumor Activity in Preclinical Models and Human Hepatocellular Carcinoma. | Mesropian A et al. | β | 2025 | β |
| Early cancer diagnosis <i>via</i> interpretable two-layer machine learning of plasma extracellular vesicle long RNA. | Liu SC et al. | β | 2025 | β |
| Early-phase impact of obesity-associated stress on murine vascular smooth muscle cells depends on EGFR and sex. | Dubourg V et al. | β | 2025 | β |
| Effect of creep-feeding supplementation during the pre-weaning phase on gene co-expression in Longissimus thoracis muscle of F1 Angus x Nellore calves at weaning. | Reolon HG et al. | β | 2025 | β |
| Effect of Selection for Low and High <i>Varroa destructor</i> Population Growth Rates on the Honey Bee Transcriptome. | De la Mora A et al. | β | 2025 | β |
| Effects of disease severity on RNA integrity measures in necrotising soft tissue infection as a possible source of research bias: An observational cohort study. | Vinkel J et al. | β | 2025 | β |
| Effects of Food Enrichment Based on Diverse Feeding Regimes on Growth, Immunity, and Stress Resistance of <i>Nibea albiflora</i>. | Ruan Y et al. | β | 2025 | β |
| Effects of metabolic overload and detoxification paralysis mechanisms of PAHs on the physiological immunity of large yellow croaker. | Huang C et al. | β | 2025 | β |
| Effects of Sleeve Gastrectomy on Blood Pressure Reduction in Diet-Induced Obese Hypertensive Rats: A Potential Role of Prouroguanylin. | Matsuda N et al. | β | 2025 | β |
| Effects of two longevity interventions, calorie restriction and rapamycin treatment, on the kynurenine-aryl hydrocarbon receptor pathway in aging skeletal muscle. | Hamrick MW et al. | β | 2025 | β |
| Egg-laying ChickenGTEx resource deciphers context-specific regulatory effects on fertility traits. | Zhu D et al. | β | 2025 | β |
| Elevated expression of SIGLEC8 in skin cutaneous melanoma predicts better prognosis associated with hematopoietic cell lineage pathway. | Li F et al. | β | 2025 | β |
| Elevated synaptic PKA activity and abnormal striatal dopamine signaling in Akap11 mutant mice, a genetic model of schizophrenia and bipolar disorder. | Song BJ et al. | β | 2025 | β |
| Embryo vitrification disturbs the pre-implantation DNA demethylation process and affects hepatic functions to threaten long-term metabolic health in mice. | Ying Y et al. | β | 2025 | β |
| Endometrial Signatures of Subfertility in Beef Heifers Reveal Dysregulation of MAPK Signaling and Ciliary Function. | Kertz NC et al. | β | 2025 | β |
| Enhancing Cryopreservation Efficiency in <i>Populus davidiana</i> Γ <i>P. tremuloides</i> Shoot Tips: Optimization of Vitrification Protocols and Mechanistic Insights into Flavonoid-Mediated Stress Adaptation. | Yang P et al. | β | 2025 | β |
| Epigenetic and transcriptomic alterations precede amyloidosis in the Alzheimer's disease App<sup>NL-G-F</sup> knock-in mouse model. | Okhovat M et al. | β | 2025 | β |
| Epigenetic regulation of cilia stability and kidney development by the chromatin remodeling SWI/SNF complex in zebrafish. | Cheng X et al. | β | 2025 | β |
| Epithelial WNT secretion drives niche escape of developing gastric cancer. | Lee J et al. | β | 2025 | β |
| Epstein-Barr Virus Promotes Gastric Cancer Progression by Modulating m6A-Dependent YTHDF1-TSC22D1 Axis. | An YR et al. | β | 2025 | β |
| eQTL Analysis Elucidates the Genetic Basis Underlying Transgressive Gene Expression in Nelumbo Hybrids. | Gao Z et al. | β | 2025 | β |
| Establishment and transcriptomic characterization of canine organoids from multiple tissues. | Zdyrski C et al. | β | 2025 | β |
| Evolutionary conservation of dopamine-mediated cellular plasticity in Arctic sponges (Porifera). | Kravchuk OI et al. | β | 2025 | β |
| Evolutionary Dynamics of Matrix Metalloproteases with Collagenolytic Activity in Teleosts. | Angelakopoulos R et al. | β | 2025 | β |
| EWS::FLI1 expression in human embryonic mesenchymal stem cells leads to transcriptional reprograming, defective DNA damage repair and Ewing sarcoma. | HernΓ‘ndez-MuΓ±oz I et al. | β | 2025 | β |
| Excess prenatal folic acid supplementation alters cortical DNA methylation and gene expression networks. | Haghani V et al. | β | 2025 | β |
| Exploring a Circulating miRNA Signature for PMM2-CDG: Initial Insights Toward Diagnosis, Stratification, and Monitoring. | Epifani F et al. | β | 2025 | β |
| Exploring the diagnostic and prognostic potential of LCFAs' metabolic and biosynthetic pathways in glioblastoma multiforme using a bioinformatics approach. | Heydarian A et al. | β | 2025 | β |
| Exploring transcriptomic and genomic differences between susceptible and resistant fetal pigs to maternal PRRSV infection at late gestation. | Ko H et al. | β | 2025 | β |
| Exploring tumor dynamics and responses of prostate cancer to IL-27 based treatment combinations through biodynamic imaging and RNA sequencing analyses. | Kumar S et al. | β | 2025 | β |
| Extracellular Vesicles Derived From Antral Follicles Significantly Change the Transcriptional Profile of Cumulus Cells and Oocytes During Pre-In Vitro Maturation in Cattle. | Mingoti GZ et al. | β | 2025 | β |
| Extracellular Vesicles from iPSC-Derived Glial Progenitor Cells Prevent Glutamate-Induced Excitotoxicity by Stabilising Calcium Oscillations and Mitochondrial Depolarisation. | Shedenkova M et al. | β | 2025 | β |
| Extracellular vesicles modulate integrin signaling and subcellular energetics to promote pulmonary lymphangioleiomyomatosis metastasis. | Kalvala AK et al. | β | 2025 | β |
| EZH2 expression in hepatocellular carcinoma and its relationship with circadian rhythm-related genes. | Wang X et al. | β | 2025 | β |
| EZHIP boosts neuronal-like synaptic gene programs and depresses polyamine metabolism. | Hasheminasabgorji E et al. | β | 2025 | β |
| FcRΞ³-Dependent NK Cell Licensing through CD244 Promotes Antitumor Immunity. | Duhan V et al. | β | 2025 | β |
| Features of DNA methylome in Capsicum spp. | Liu Y et al. | β | 2025 | β |
| Filovirus infection disrupts epithelial barrier function and ion transport in human iPSC-derived gut organoids. | Flores EY et al. | β | 2025 | β |
| From bench to bytes: a practical guide to RNA sequencing data analysis. | Dawadi P et al. | β | 2025 | β |
| From bulk RNA sequencing to spatial transcriptomics: a comparative review of differential gene expression analysis methods. | Kalantari-Dehaghi M et al. | β | 2025 | β |
| From juvenile to adult: investigating miRNAs, gene expression, and the juvenile cone in olive development. | Romero-RodrΓguez P et al. | β | 2025 | β |
| Functional Expansion of the Skin Microbiome: A Pantothenate-Producing <i>Rothia</i> Strain Confers Anti-Inflammatory and Photoaging-Protective Effects. | Kim HB et al. | β | 2025 | β |
| Functional genomics and tumor microenvironment analysis reveal prognostic biological subtypes in Mantle cell lymphoma. | Sharma S et al. | β | 2025 | β |
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| Functionally diversified Caenorhabditis elegans BiP orthologs control body growth, reproduction, stress resistance, aging, and autophagy. | Urban ND et al. | β | 2025 | β |
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| Genome graphs reveal the importance of structural variation in Mycobacterium tuberculosis evolution and drug resistance. | Canalda-Baltrons A et al. | β | 2025 | β |
| Genomes of the entomopathogenic nematode Steinernema hermaphroditum and its associated bacteria. | Schwarz EM et al. | β | 2025 | β |
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| Genome-Wide Characterization of <i>SlABCG</i> Genes in Tomato Reveals Their Role in Saline-Alkali Tolerance. | Li Y et al. | β | 2025 | β |
| Genome-wide identification of the MADS-box gene family and their role in the formation of faba bean (Vicia faba L.) growth habits. | Zhou X et al. | β | 2025 | β |
| Genome-wide screen uncovers novel host factors for L-A virus maintenance and a potential mutualistic-symbiosis relationship in yeast. | Hsiao WY et al. | β | 2025 | β |
| Genome-wide transcriptional analysis of rapeseed (Brassica napus L.) responses to heat stress: an integrated RNA-Seq meta-analysis, gene co-expression, and gene regulatory network study. | Shahsavari M et al. | β | 2025 | β |
| Genomic pathogenic alterations in the SWI/SNF complex compromise the outcomes of immunotherapy in Chinese patients with KRAS-mutant NSCLC by downregulating STING expression. | Gao L et al. | β | 2025 | β |
| Genomic resources for the scuttle fly Megaselia abdita: a model organism for comparative developmental studies in flies. | Tenger-Trolander A et al. | β | 2025 | β |
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| Harnessing plasma transcriptomics for non-invasive cancer biomarker identification: a comprehensive review. | Mohamed NMHN et al. | β | 2025 | β |
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| High Shear Stress-Induced Endothelial Piezo1 Downregulation Promotes Intracranial Aneurysm Formation via the PDGF-BB/PDGFRΞ² Paracrine Signaling Pathway. | Lu Z et al. | β | 2025 | β |
| Host gene expression in the Nasopharynx can discriminate microbiologically confirmed viral and bacterial lower respiratory tract infection. | Tillekeratne LG et al. | β | 2025 | β |
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| Identification of miRNAs in Response to Cold Stress in 'Chaling' Common Wild Rice (<i>Oryza rufipogon</i> Griff.). | Gao F et al. | β | 2025 | β |
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| Integrative multi-omics reveals common and distinct pathogenic mechanisms and preoperative diagnostic signatures in breast fibroepithelial lesions. | He M et al. | β | 2025 | β |
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| Integrative Regulatory Networks of MicroRNA-483: Unveiling Its Systematic Role in Human Diseases and Clinical Implications. | Xu J et al. | β | 2025 | β |
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| Investigation of Novel Predictive Biomarkers for Preeclampsia in Second-Trimester Amniotic Fluid. | Lee HE et al. | β | 2025 | β |
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| Joint profiling of gene expression and chromatin accessibility in pancreatic lymph nodes and spleens in human type 1 diabetes. | Abedi M et al. | β | 2025 | β |
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| Lipocalin-2 drives brain metastatic progression through reciprocal tumor-microenvironment interactions in lung cancer. | Zhu Y et al. | β | 2025 | β |
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| Stratification of telomerase activity in cancer reveals associations with senescence and genomic instability. | Noureen N et al. | β | 2025 | β |
| SwitchTFI: identifying transcription factors driving cell differentiation. | Martini P et al. | β | 2025 | β |
| Synovial Fluid and Serum MicroRNA Signatures in Equine Osteoarthritis. | Castanheira CIGD et al. | β | 2025 | β |
| Synovial Fluid MicroRNA Biomarkers Enable Accurate Diagnosis of Hip and Knee Periprosthetic Joint Infections. | Frank BJH et al. | β | 2025 | β |
| System analysis links SMARCD3 regulons to growth signaling and MEK inhibitor response in everolimus-resistant ER+ breast cancer cells. | Medina EF et al. | β | 2025 | β |
| Systematic characterization of the composition and dynamics of processing body-associated mRNAs. | Sun Z et al. | β | 2025 | β |
| Systematic discovery of subcellular RNA patterns in the gut epithelium. | Lee M et al. | β | 2025 | β |
| Targeting ATR offers multifaceted treatment strategies involving RAD51-mediated compensatory DNA repair in bladder cancer. | Pannhausen J et al. | β | 2025 | β |
| Targeting SUMOylation promotes cBAF complex stabilization and disruption of the SS18::SSX transcriptome in synovial sarcoma. | Floros KV et al. | β | 2025 | β |
| Targeting the MEK/ERK Pathway to Suppress P-Glycoprotein and Reverse Carfilzomib Resistance in Multiple Myeloma. | Laletina LA et al. | β | 2025 | β |
| TET3 protects the <i>Dlk1-Dio3</i> imprinted locus from DNA hypomethylation during adult NSC reprogramming. | LΓ‘zaro-Carot L et al. | β | 2025 | β |
| The aryl hydrocarbon receptor is associated with monocytic AML and innate immune resistance reversible with an AHR inhibitor. | Saultz JN et al. | β | 2025 | β |
| The cervicovaginal microbiome associates with spatially restricted host transcriptional signatures throughout the human ectocervical epithelium and submucosa. | Kaldhusdal V et al. | β | 2025 | β |
| The Disruption of <i>Cyp7b1</i> Controls IGFBP2 and Prediabetes Exerted Through Different Hydroxycholesterol Metabolites. | MartΓnez-Beamonte R et al. | β | 2025 | β |
| The horse cardiac transcriptome: Moving towards a molecular understanding of atrial fibrillation. | Haugaard SL et al. | β | 2025 | β |
| The mouse neonatal small intestine is regionally specialized for protein absorption and transepithelial transport. | Block CL et al. | β | 2025 | β |
| The neuronal chromatin landscape in brains from individuals with schizophrenia is linked to early fetal development. | Girdhar K et al. | β | 2025 | β |
| The offonome reveals on and off states of gene expression near the detection limit of RNA-seq. | Choi WY et al. | β | 2025 | β |
| The oncogenic potential of YAP requires Y357 phosphorylation in cholangiocytes but not in hepatocytes. | Aksu MD et al. | β | 2025 | β |
| The R2R3-MYB transcription factor GhMYB315 associates with GhVQ28 to enhance Verticillium wilt resistance in upland cotton by regulating phenylpropanoid metabolism. | Guo Y et al. | β | 2025 | β |
| The receptor tyrosine kinase ErbB2/HER2 governs CDK4 inhibitor sensitivity, timing, and irreversibility of the G1/S transition. | Nagasato-Ichikawa A et al. | β | 2025 | β |
| The recombinant zoster vaccine induces trained immunity in monocytes through persistent downregulation of TGFΞ². | Johnson MJ et al. | β | 2025 | β |
| The RNA-binding protein CPEB1 marks healthy adult Ξ² cells in mice but is dispensable for Ξ² cell identity and function. | Nimkulrat SD et al. | β | 2025 | β |
| The RNA N<sup>6</sup>-methyladenosine methylome coordinates long non-coding RNAs to mediate cancer drug resistance by activating PI3K signaling. | Tan Y et al. | β | 2025 | β |
| The Salmonella pathogenicity island 1 injectisome reprograms host cell translation to evade the inflammatory response. | Wood G et al. | β | 2025 | β |
| The systemic wrinkled skin phenotype involves aberrant expression and variation of genes related to the oxidative stress and extracellular matrix in Xiang pigs. | Hu F et al. | β | 2025 | β |
| The volatile profiles of three strawberry varieties exhibit common and distinct responses to the inoculation with Rhizophagus irregularis and different Pseudomonas fluorescens strains. | Boussageon R et al. | β | 2025 | β |
| THRESHOLD: a comprehensive transcriptomic analysis tool for evaluating gene saturation and impact in disease progression. | Gammell F et al. | β | 2025 | β |
| Thrombopoietin increases susceptibility for EVI1β+βKMT2A-MLLT3-driven AML expressing stem cell genes linked to poor outcome. | ChΓ’tel-Soulet HΓ et al. | β | 2025 | β |
| Thrombospondin-4 regulates apoptosis of vascular smooth muscle cells after artery transplanted into vein. | Xu F et al. | β | 2025 | β |
| Tick-borne encephalitis virus variants drive distinct TCR repertoire alterations. | Salnikova MA et al. | β | 2025 | β |
| Time-Series Comparative Transcriptome Analyses of Two Potato Cultivars with Different Verticillium Wilt Resistance. | Fan G et al. | β | 2025 | β |
| TIMP1 as a context-dependent biomarker linking cancer progression and cardiovascular disorders: a multi-level and bioinformatics study. | Xie H et al. | β | 2025 | β |
| Tissue-Specific Gene Expression of Digestive Tract Glands in <i>Paroctopus digueti</i>: Insights for Cephalopod Biology and Aquaculture. | MartΓnez-Morales MG et al. | β | 2025 | β |
| Tissue-Specific Transcriptomic Profiling of Vitamin-Dependent Mitochondrial Pathways in Female Buffalo. | Sadeesh EM et al. | β | 2025 | β |
| TMPRSS11B promotes an acidified microenvironment and immune suppression in squamous lung cancer. | Sunil HS et al. | β | 2025 | β |
| Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes. | UuskΓΌla-Reimand L et al. | β | 2025 | β |
| Transcriptional and metabolic modeling analyses of developing <i>Aspergillus fumigatus</i> biofilms reveal metabolic shifts required for biofilm maturation. | Puerner C et al. | β | 2025 | β |
| Transcriptional network analysis of PTEN-protein-deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication. | Rondon-Lorefice I et al. | β | 2025 | β |
| Transcription factor Zfx regulates tumor's evasion to T cell killing in immunotherapy. | Kaufmann U et al. | β | 2025 | β |
| Transcriptome analyses of human corneal endothelial cell lines derived from patients with Fuchs endothelial corneal dystrophy. | Ashraf S et al. | β | 2025 | β |
| Transcriptome analysis reveals key immune pathways and metabolites associated with resistance to Verticillium dahliae in GbMBL1.1A-overexpressing cotton. | Tan D et al. | β | 2025 | β |
| Transcriptome analysis unveils Th1 cell cycle signature as a distinctive feature ofΒ mixed connective tissue disease. | Suwa Y et al. | β | 2025 | β |
| Transcriptome and Metabolome Analysis Reveal the Reasons for the Formation of Tissue Specificity and Quality in the Underground Part of Saposhnikovia divaricata (Turcz.) Schischk. | Chen Y et al. | β | 2025 | β |
| Transcriptome and small RNA sequencings reveal the response of tobacco to aphid infestation. | Li JY et al. | β | 2025 | β |
| Transcriptome-Guided Analysis and Application of the Mechanisms Influencing PamyE Promoter Activity. | Guo J et al. | β | 2025 | β |
| Transcriptomic and Metabolic Profiles of Apple Peels of Different Colors. | Ao P et al. | β | 2025 | β |
| Transcriptomic Changes Underlying the Anti-Steatotic Effects of DHA Supplementation in Aged Obese Female Mice. | Pejenaute MartΓnez de Lizarrondo Γ et al. | β | 2025 | β |
| Transcriptomic profiling during normothermic machine perfusion of human kidneys reveals a pro-inflammatory cellular landscape and gene expression signature associated with severe ischemia-reperfusion injury and delayed graft function. | Spiers HVM et al. | β | 2025 | β |
| Transcriptomic profiling in human lung organoids uncovers metallothionein response as a signature of PHMG-p-induced lung toxicity. | Kim S et al. | β | 2025 | β |
| Transcriptomic Profiling Reveals Biphasic Regulatory Instability and Late-Stage Proteostatic Decline in Aging Mouse Oocytese. | Dinh PTN et al. | β | 2025 | β |
| Transcriptomics and Metabolomics Insights into the Dysregulation of Chondrocyte Differentiation Induced by T-2 Toxin. | Cheng S et al. | β | 2025 | β |
| Transcriptomics at the thermal limits of an urban introduced lizard. | Fontaine SS et al. | β | 2025 | β |
| Transomic analysis reveals DNA methylation and transcription factor roles in obese liver protein expression. | Maehara H et al. | β | 2025 | β |
| TREM2 Deficiency Regulates Macrophage Apoptosis and Repair in Radiation-Induced Skin Injury. | Chen Z et al. | β | 2025 | β |
| Triploidy drives vector capacity and expansion of the parthenogenetic tick Haemaphysalis longicornis. | Wang T et al. | β | 2025 | β |
| TSSKL is essential for sperm mitochondrial morphogenesis and male fertility in moths. | Xu X et al. | β | 2025 | β |
| Tumour sampling conditions perturb the metabolic landscape of clear cell renal cell carcinoma. | Yong C et al. | β | 2025 | β |
| Two Cohorts, One Network: Consensus Master Regulators Orchestrating Papillary Thyroid Carcinoma. | Tapia-Carrillo D et al. | β | 2025 | β |
| Unveiling distinct storage composition and starch properties in developing indica rice grains via transcriptional profiling and enzymatic activity analysis. | Sangwongchai W et al. | β | 2025 | β |
| Unveiling Dynamic Defense Pathways: Transcriptome Analysis of Phenylpropanoids and (Iso)flavonoids in Cowpea Leaves Post-CABMV Inoculation. | de Andrade Luz G et al. | β | 2025 | β |
| Unveiling long-term prenatal nutrition biomarkers in beef cattle via multi-tissue and multi-OMICs analysis. | Polizel GHG et al. | β | 2025 | β |
| Using transcriptome analysis and QTL mapping to decipher the genetic basis of heterosis in potato root system. | Yang J et al. | β | 2025 | β |
| Vaccine-educated T cells and a CD123 bispecific T-cell engager for treatment of acute myeloid leukemia. | Liegel J et al. | β | 2025 | β |
| Variability in intrinsic promoter strength underlies the temporal hierarchy of the Caulobacter SOS response induction. | Kamat A et al. | β | 2025 | β |
| WEE1 inhibitors trigger GCN2-mediated activation of the integrated stress response. | Tjeerdsma RB et al. | β | 2025 | β |
| Whole body regeneration deploys a rewired embryonic gene regulatory network logic. | Andreoni-Pham R et al. | β | 2025 | β |
| Whole transcriptome sequencing reveals the functional regulation of chicken reproduction by lncRNAs, miRNAs, and mRNAs across the hypothalamus-pituitary-ovary axis. | Li P et al. | β | 2025 | β |
| Wnt signaling restores evolutionary loss of robust foot regeneration rates in Hydra. | Campos SE et al. | β | 2025 | β |
| Wnt signalling maintains self-renewal of human hepatoblasts without blocking their differentiation. | Zacharis ED et al. | β | 2025 | β |
| Xenosiderophore transporter gene expression and clade-specific filamentation in Candida auris killifish (Aphanius dispar) infection. | Gifford H et al. | β | 2025 | β |
| Zinc pyrithione impairs iron-sulfur cluster biogenesis in Mycobacterium tuberculosis. | Wang L et al. | β | 2025 | β |
| Ξ²catenin-1 localization and transcriptomic profiling provide insights into the early development of planarians. | Coronel-CΓ³rdoba P et al. | β | 2025 | β |