Decomposition and mapping of generalized spike-wave complexes.
- Authors
- Rodin, E
- Year
- 1999
- Journal
- Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
- PMID
- 10576481
- DOI
- 10.1016/s1388-2457(99)00163-7
OBJECTIVE: To delineate more precisely the electrical fields of spikes versus waves during absence seizures. METHODS: Five children with 25 absence seizures were investigated with an expanded electrode array. Spikes were separated from waves by appropriate filtering and current source density maps were obtained from different portions of the waves as well as spikes. In order to detect commonalities for spread of activity, averaging of the complexes was also carried out. RESULTS: The anterior head regions (prefrontal and fronto-polar) show independent activity from the posterior ones (parieto-occipital) for spikes as well as waves. Voltage maps give a simplified and therefore misleading picture. The complexity of the process and propagation of events is best appreciated when current source densities (CSD) are mapped and several head views are available. Spike 1 becomes clearly visible upon filtering, even when it is not apparent from raw tracings, and can be mapped. CONCLUSIONS: Future topographic investigations of the SW complex should utilize CSD maps rather than rely entirely on voltages. This applies also to seemingly focal spikes--especially in children--in order to differentiate them from a partial expression of a generalized seizure tendency.
No figures extracted from this document.
No chunks — full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
No citations found.
In this knowledge base
| Title | Year | PMID |
|---|---|---|
| The use of current source density as electrophysiological correlates in neuropsychiatric disorders: A review of human studies. | 2015 | 25448264 |
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Spatiotemporal propagation patterns of generalized ictal spikes in childhood absence epilepsy. | Kokkinos V et al. | — | 2017 | → |
| The use of current source density as electrophysiological correlates in neuropsychiatric disorders: A review of human studies. | Kamarajan C et al. | — | 2015 | → |
| Dynamic magnetic source imaging of absence seizure initialization and propagation: a magnetoencephalography study. | Miao A et al. | — | 2014 | → |
| Does greater low frequency EEG activity in normal immaturity and in children with epilepsy arise in the same neuronal network? | Michels L et al. | — | 2011 | → |
| EEG functional connectivity of the intrahemispheric cortico-cortical network of idiopathic generalized epilepsy. | Clemens B et al. | — | 2011 | → |
| Bayesian multi-modal model comparison: a case study on the generators of the spike and the wave in generalized spike-wave complexes. | Daunizeau J et al. | — | 2010 | → |
| Evidence that juvenile myoclonic epilepsy is a disorder of frontotemporal corticothalamic networks. | Holmes MD et al. | — | 2010 | → |
| Generalized spike-wave discharges involve a default mode network in patients with juvenile absence epilepsy: a MEG study. | Sakurai K et al. | — | 2010 | → |
| Spikes and epilepsy. | Rodin E et al. | — | 2009 | → |
| Transition from cortical slow oscillations of sleep to spike-wave seizures. | Tucker DM et al. | — | 2009 | → |
| Analysis of background EEG activity in patients with juvenile myoclonic epilepsy. | Santiago-Rodríguez E et al. | — | 2008 | → |
| Imaging the cortical effect of lamotrigine in patients with idiopathic generalized epilepsy: a low-resolution electromagnetic tomography (LORETA) study. | Clemens B et al. | — | 2008 | → |
| Characteristic distribution of interictal brain electrical activity in idiopathic generalized epilepsy. | Clemens B et al. | — | 2007 | → |
| Electroencephalographic characterization of spike-wave discharges in cortex and thalamus in WAG/Rij rats. | Sitnikova E et al. | — | 2007 | → |
| Proton magnetic resonance spectroscopy study of bilateral thalamus in juvenile myoclonic epilepsy. | Haki C et al. | — | 2007 | → |
| Source localization of periodic sharp wave complexes using independent component analysis in sporadic Creutzfeldt-Jakob disease. | Jung KY et al. | — | 2007 | → |
| Cortical and thalamic coherence during spike-wave seizures in WAG/Rij rats. | Sitnikova E et al. | — | 2006 | → |
| Naming seizures. | Faught E | — | 2005 | → |
| Are "generalized" seizures truly generalized? Evidence of localized mesial frontal and frontopolar discharges in absence. | Holmes MD et al. | — | 2004 | → |
| Magnetoencephalographic spikes not detected by conventional electroencephalography. | Rodin E et al. | — | 2004 | → |
| Neocortical seizures: initiation, development and cessation. | Timofeev I et al. | — | 2004 | → |
| Functional magnetic resonance imaging of human absence seizures. | Salek-Haddadi A et al. | — | 2003 | → |
| Source analysis of polyspike and wave complexes in juvenile myoclonic epilepsy. | Santiago-Rodríguez E et al. | — | 2002 | → |
| Involvement of the thalamocortical system in epileptic loss of consciousness. | Kostopoulos GK | — | 2001 | → |
| Absence seizures and the frontal lobe. | Pavone A et al. | — | 2000 | → |
| Spike-and-wave discharges of absence seizures as a transformation of sleep spindles: the continuing development of a hypothesis. | Kostopoulos GK | — | 2000 | → |