g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update).
- Authors
- Raudvere, Uku; Kolberg, Liis; Kuzmin, Ivan; Arak, Tambet; Adler, Priit; Peterson, Hedi; Vilo, Jaak
- Year
- 2019
- Journal
- Nucleic acids research
- PMID
- 31066453
- DOI
- 10.1093/nar/gkz369
- PMCID
- PMC6602461
Biological data analysis often deals with lists of genes arising from various studies. The g:Profiler toolset is widely used for finding biological categories enriched in gene lists, conversions between gene identifiers and mappings to their orthologs. The mission of g:Profiler is to provide a reliable service based on up-to-date high quality data in a convenient manner across many evidence types, identifier spaces and organisms. g:Profiler relies on Ensembl as a primary data source and follows their quarterly release cycle while updating the other data sources simultaneously. The current update provides a better user experience due to a modern responsive web interface, standardised API and libraries. The results are delivered through an interactive and configurable web design. Results can be downloaded as publication ready visualisations or delimited text files. In the current update we have extended the support to 467 species and strains, including vertebrates, plants, fungi, insects and parasites. By supporting user uploaded custom GMT files, g:Profiler is now capable of analysing data from any organism. All past releases are maintained for reproducibility and transparency. The 2019 update introduces an extensive technical rewrite making the services faster and more flexible. g:Profiler is freely available at https://biit.cs.ut.ee/gprofiler.
The growth of available species/strains in g:Profiler since 2012. Each column represents an archive version, the current version is highlighted in blue. The isolated peak in 1185_e69_eg16 refers to a version where we incorporated bacterial species to g:Profiler but due to differences in the underlying database structure we dropped them again from further releases.
Example of g:GOSt multiquery Manhattan plot. (A) Name of the query. (B) X-axis shows the functional terms grouped and colour-coded by data source. (C, D) The position of terms in the plots is fixed and terms from the same (GO) branch are close to each other. (E) P-values in the table outputs are color-coded from yellow (insignificant) to blue (highly significant). (F) Data sources that were not included in the analysis are shown in grey. (G) Hovering over the term circle shows a tooltip with the most relevant information. (H) In case of a multiquery, the same term is also highlighted on other plots. (I) The P-values from other queries are indicated in red next to the y-axis for easier comparison. (J) A click allows to pin the circles to the plot together with a numeric ID and creates a more detailed result table below the image.
| Name | Type |
|---|---|
| BerkeleyDB local | drug |
| cell communication local | phenotype |
| development | phenotype |
| disease specific genes local | gene |
| Ensembl Biomart local | drug |
| Ensembl gene identifiers (ENSG) local | drug |
| Ensembl Variation Data local | cohort |
| eQTL analysis local | cohort |
| g:Convert local | drug |
| g:Profiler local | drug |
| GWAS | cohort |
| human | cohort |
| human adipose tissue-derived stem cells local | cohort |
| NumPy local | drug |
| osteogenesis local | phenotype |
| pandas local | drug |
| polysomal RNA fraction local | drug |
| polysomes local | drug |
| protein coding Ensembl gene local | gene |
| protein-coding gene | gene |
| response to external stimuli local | phenotype |
| Roaring bitmaps local | drug |
| rs7961894 local | variant |
| SciPy local | drug |
| Sequence Ontology local | drug |
| SNP | cohort |
| SQLite local | drug |
| statsmodels local | drug |
| total mRNA local | drug |
| trait | phenotype |
No uploaded files.
| Citation | PMID | DOI | Status |
|---|---|---|---|
| AdlerP., KoldeR., KullM., TkachenkoA., PetersonH., ReimandJ., ViloJ. Mining for coexpression across hundreds of datasets using novel rank aggregation and visualization methods. Genome Biol.2009; 10:R139.1996159910.1186/gb-2009-10-12-r139PMC2812946 | β | β | β |
| AfganE., BakerD., BatutB., Van Den BeekM., BouvierD., ΔechM., ChiltonJ., ClementsD., CoraorN., GrΓΌningB.A.et al. The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update. Nucleic Acids Res.2018; 46:W537βW544.2979098910.1093/nar/gky379PMC6030816 | β | β | β |
| AlexaA., RahnenfuhrerJ. topGO: enrichment analysis for gene ontology. R Package Version. 2010; 2:2010. | β | β | β |
| AshburnerM., BallC.A., BlakeJ.A., BotsteinD., ButlerH., CherryJ.M., DavisA.P., DolinskiK., DwightS.S., EppigJ.T.et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat. Genet.2000; 25:25β29.1080265110.1038/75556PMC3037419 | β | β | β |
| BraunerB., MontroneC., FoboG., FrishmanG., Dunger-KaltenbachI., ReinhardJ., GiurgiuM., RueppA. CORUM: the comprehensive resource of mammalian protein complexes2019. Nucleic Acids Res.2018; 47:D559βD563.10.1093/nar/gky973PMC632397030357367 | β | β | β |
| ConsortiumT.U. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Res.2018; 47:D506βD515.10.1093/nar/gky1049PMC632399230395287 | β | β | β |
| CunninghamF., MooreB., Ruiz-SchultzN., RitchieG.R., EilbeckK. Improving the Sequence Ontology terminology for genomic variant annotation. J. Biomed. Semantics. 2015; 6:32.2622958510.1186/s13326-015-0030-4PMC4520272 | β | β | β |
| FabregatA., JupeS., MatthewsL., SidiropoulosK., GillespieM., GarapatiP., HawR., JassalB., KorningerF., MayB.et al. The Reactome Pathway Knowledgebase. Nucleic Acids Res.2017; 46:D649βD655.10.1093/nar/gkx1132PMC575318729145629 | β | β | β |
| FrankishA., AbdulSalamA.I., VulloA., ZadissaA., WinterbottomA., PartonA., YatesA.D., ThormannA., ParkerA., McMahonA.C.et al. Ensembl 2019. Nucleic Acids Res.2018; 47:D745βD751. | β | β | β |
| Gutirrez-SacristnA., BravoΓ., CentenoE., SanzF., PieroJ., Garca-GarcaJ., Deu-PonsJ., Queralt-RosinachN., FurlongL.I. DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants. Nucleic Acids Res.2016; 45:D833βD839.2792401810.1093/nar/gkw943PMC5210640 | β | β | β |
| HoweK.L., BoltB.J., ShafieM., KerseyP., BerrimanM. WormBase ParaSite a comprehensive resource for helminth genomics. Mol. Biochem. Parasitol.2017; 215:2β10.2789927910.1016/j.molbiopara.2016.11.005PMC5486357 | β | β | β |
| HuntS.E., McLarenW., GilL., ThormannA., SchuilenburgH., SheppardD., PartonA., ArmeanI.M., TrevanionS.J., FlicekP.et al. Ensembl variation resources. Database. 2018; 2018:bay119.10.1093/database/bay119PMC631051330576484 | β | β | β |
| KhatriP., SirotaM., ButteA.J. Ten years of pathway analysis: current approaches and outstanding challenges. PLoS Comput. Biol.2012; 8:e1002375.2238386510.1371/journal.pcbi.1002375PMC3285573 | β | β | β |
| KinsellaR.J., KΓ€hΓ€riA., HaiderS., ZamoraJ., ProctorG., SpudichG., Almeida-KingJ., StainesD., DerwentP., KerhornouA.et al. Ensembl BioMarts: a hub for data retrieval across taxonomic space. Database. 2011; 2011:bar030.2178514210.1093/database/bar030PMC3170168 | β | β | β |
| KolbergL., KuzminI., AdlerP., ViloJ., PetersonH. funcExplorer: a tool for fast data-driven functional characterisation of high-throughput expression data. BMC Genomics. 2018; 19:817.3042883110.1186/s12864-018-5176-xPMC6236982 | β | β | β |
| KΓΆhlerS., GratianD., BaynamG., PalmerR., DawkinsH., SegalM., JansenA.C., BrudnoM., ChangW.H., FreemanA.F.et al. Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources. Nucleic Acids Res.2018; 47:D1018βD1027.10.1093/nar/gky1105PMC632407430476213 | β | β | β |
| LachmannA., RouillardA.D., MonteiroC.D., GundersenG.W., JagodnikK.M., JonesM.R., KuleshovM.V., McDermottM.G., FernandezN.F., DuanQ.et al. Enrichr: a comprehensive gene set enrichment analysis web server 2016 update. Nucleic Acids Res.2016; 44:W90βW97.2714196110.1093/nar/gkw377PMC4987924 | β | β | β |
| LemireD., KaiG.S.Y., KaserO. Consistently faster and smaller compressed bitmaps with Roaring. 2016; arXiv doi:21 March 2016, preprint: not peer reviewedhttps://arxiv.org/abs/1603.06549. | β | β | β |
| LiangC., TuS.-J., ChengY.-N., ChouC.-H., HuangW.-C., HuangH.-D., HuangP.-C., WengS.-L., HsuW.-L., TaiC.-S.et al. miRTarBase update 2018: a resource for experimentally validated microRNA-target interactions. Nucleic Acids Res.2017; 46:D296βD302.10.1093/nar/gkx1067PMC575322229126174 | β | β | β |
| LiberzonA., SubramanianA., PinchbackR., ThorvaldsdttirH., TamayoP., MesirovJ. Molecular signatures database (MSigDB) 3.0. Bioinformatics. 2011; 27:1739β1740.2154639310.1093/bioinformatics/btr260PMC3106198 | β | β | β |
| MatysV., Kel-MargoulisO.V., FrickeE., LiebichI., LandS., Barre-DirrieA., ReuterI., ChekmenevD., KrullM., HornischerK.et al. TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes. Nucleic Acids Res.2006; 34:D108βD110.1638182510.1093/nar/gkj143PMC1347505 | β | β | β |
| MetsaluT., ViloJ. ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap. Nucleic Acids Res.2015; 43:W566βW570.2596944710.1093/nar/gkv468PMC4489295 | β | β | β |
| MorishimaK., TanabeM., FurumichiM., KanehisaM., SatoY. New approach for understanding genome variations in KEGG. Nucleic Acids Res.2018; 47:D590βD595.10.1093/nar/gky962PMC632407030321428 | β | β | β |
| ReimandJ., ArakT., AdlerP., KolbergL., ReisbergS., PetersonH., ViloJ. g:Profiler β a web server for functional interpretation of gene lists (2016 update). Nucleic Acids Res.2016; 44:W83βW89.2709804210.1093/nar/gkw199PMC4987867 | β | β | β |
| ReimandJ., ArakT., ViloJ. g:Profiler β a web server for functional interpretation of gene lists (2011 update). Nucleic Acids Res.2011; 39:W307βW315.2164634310.1093/nar/gkr378PMC3125778 | β | β | β |
| ReimandJ., IsserlinR., VoisinV., KuceraM., Tannus-LopesC., RostamianfarA., WadiL., MeyerM., WongJ., XuC.et al. Pathway enrichment analysis and visualization of omics data using g:Profiler, GSEA, Cytoscape and EnrichmentMap. Nat. Protoc.2019; 14:482β517.3066467910.1038/s41596-018-0103-9PMC6607905 | β | β | β |
| ReimandJ., KullM., PetersonH., HansenJ., ViloJ. g:Profiler β a web-based toolset for functional profiling of gene lists from large-scale experiments. Nucleic Acids Res.2007; 35:W193βW200.1747851510.1093/nar/gkm226PMC1933153 | β | β | β |
| RobertA.W., AngulskiA.B.B., SpangenbergL., ShigunovP., PereiraI.T., BettesP.S.L., NayaH., CorreaA., DallagiovannaB., StimamiglioM.A. Gene expression analysis of human adipose tissue-derived stem cells during the initial steps of in vitro osteogenesis. Scientific Rep.2018; 8:4739.10.1038/s41598-018-22991-6PMC585679329549281 | β | β | β |
| ShannonP., MarkielA., OzierO., BaligaN.S., WangJ.T., RamageD., AminN., SchwikowskiB., IdekerT. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res.2003; 13:2498β2504.1459765810.1101/gr.1239303PMC403769 | β | β | β |
| SlenterD.N., KutmonM., HanspersK., RiuttaA., WindsorJ., NunesN., MliusJ., CirilloE., CoortS.L., DiglesD.et al. WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research. Nucleic Acids Res.2017; 46:D661βD667.10.1093/nar/gkx1064PMC575327029136241 | β | β | β |
| SubramanianA., TamayoP., MoothaV.K., MukherjeeS., EbertB.L., GilletteM.A., PaulovichA., PomeroyS.L., GolubT.R., LanderE.S.et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. U.S.A.2005; 102:15545β15550.1619951710.1073/pnas.0506580102PMC1239896 | β | β | β |
| SupekF., BoΕ‘njakM., Ε kuncaN., Ε mucT. REVIGO summarizes and visualizes long lists of gene ontology terms. PLoS One. 2011; 6:e21800.2178918210.1371/journal.pone.0021800PMC3138752 | β | β | β |
| TripathiS., PohlM.O., ZhouY., Rodriguez-FrandsenA., WangG., SteinD.A., MoultonH.M., DeJesusP., CheJ., MulderL.C.et al. Meta- and orthogonal integration of influenza βOMICsβ data defines a role for UBR4 in virus budding. Cell Host Microbe. 2015; 18:723β735.2665194810.1016/j.chom.2015.11.002PMC4829074 | β | β | β |
| UhlΓ©nM., FagerbergL., HallstrΓΆmB.M., LindskogC., OksvoldP., MardinogluA., SivertssonΓ ., KampfC., SjΓΆstedtE., AsplundA.et al. Tissue-based map of the human proteome. Science. 2015; 347:1260419.2561390010.1126/science.1260419 | β | β | β |
| WadiL., MeyerM., WeiserJ., SteinL.D., ReimandJ. Impact of outdated gene annotations on pathway enrichment analysis. Nat.Methods. 2016; 13:705.2757562110.1038/nmeth.3963PMC7802636 | β | β | β |
| WangJ., VasaikarS., ShiZ., ZhangB., GreerM. WebGestalt 2017: a more comprehensive, powerful, flexible and interactive gene set enrichment analysis toolkit. Nucleic Acids Res.2017; 45:W130βW137.2847251110.1093/nar/gkx356PMC5570149 | β | β | β |
| Whirl-CarrilloM., McDonaghE.M., HebertJ.M., GongL., SangkuhlK., ThornC.F., AltmanR.B., KleinT.E. Pharmacogenomics knowledge for personalized medicine. Clin. Pharmacol. Ther.2012; 92:414β417.2299266810.1038/clpt.2012.96PMC3660037 | β | β | β |
| XieC., LiC.-Y., GaoG., HuangJ., WuJ., KongL., DongS., MaoX., DingY., WeiL. KOBAS 2.0: a web server for annotation and identification of enriched pathways and diseases. Nucleic Acids Res.2011; 39:W316βW322.2171538610.1093/nar/gkr483PMC3125809 | β | β | β |
| YanH., YouQ., TianT., YiX., LiuY., DuZ., XuW., SuZ. agriGO v2.0: a GO analysis toolkit for the agricultural community, 2017 update. Nucleic Acids Res.2017; 45:W122βW129.2847243210.1093/nar/gkx382PMC5793732 | β | β | β |
In this knowledge base
| Title | Year | PMID |
|---|---|---|
| Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder. | 2025 | 41083468 |
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Aberrant epithelial differentiation may contribute to endometrial polyp formation: insights from single-cell analysis. | Pathare ADS et al. | β | 2026 | β |
| A case-based explainable graph neural network framework for mechanistic drug repositioning. | Gonzalez-Cavazos AC et al. | β | 2026 | β |
| Activation of Neutrophil Extracellular Trap Formation in Patients with Heart Failure and a Preserved Ejection Fraction. | VAN Essen BJ et al. | β | 2026 | β |
| Acyl-CoA-binding protein (ACBP): a poor-prognosis biomarker in sepsis and a target for disease mitigation. | Lambertucci F et al. | β | 2026 | β |
| Adolescent White Matter Maturation Mediates Epigenetic Associations With Cognitive Development. | Jensen D et al. | β | 2026 | β |
| A dynamic RNA editing landscape in porcine spleen highlights a post-transcriptional mechanism for immune maturation. | Zeng L et al. | β | 2026 | β |
| Aebp1 loss in osteoprogenitors leads to skeletal defects resembling Ehlers-Danlos Syndrome by diminishing Wnt/Ξ²-catenin signaling. | Feng S et al. | β | 2026 | β |
| Affinity-Based Interactome Mapping of Inositol Pyrophosphates Reveals 4/6-PP-InsP<sub>5</sub>-Binding Proteins in Plants. | Ritter K et al. | β | 2026 | β |
| Age-dependent immune responses and resident cell dynamics in young mice following pneumonia. | Michki SN et al. | β | 2026 | β |
| A genome-scale single-cell CRISPRi map of trans gene regulation across human pluripotent stem cell lines. | Feng C et al. | β | 2026 | β |
| AMF primes immune genes against Puccinia hordei (Brown rust) in Hordeum vulgare but does not reduce pathogen burden. | Moulton-Brown C et al. | β | 2026 | β |
| An Assembly of the Global Phosphoproteomic Network of an Underexplored Kinase CDK17: Possible Implications in Cell Cycle Regulation. | Bangera A et al. | β | 2026 | β |
| A single-cell spatiotemporal transcriptomic atlas of mouse prefrontal cortex maps dynamics of intratelencephalic neurons during postnatal development. | Zheng H et al. | β | 2026 | β |
| Association of the endosomal sorting processes cargo selection and membrane tubulation with human reward system reactivity. | Treutlein J et al. | β | 2026 | β |
| A sub-set of guanine- and cytosine-rich genes are actively transcribed at the nuclear lamin B1 region. | Balasooriya GI et al. | β | 2026 | β |
| Biological underpinnings and genetic predisposition to schizophrenia within microrna-137 regulatory pathways across brain development. | Stella C et al. | β | 2026 | β |
| Bulk RNA sequence analysis of the articular disc-retrodiscal tissue complex in a TMJ-OA rat model with anterior disc displacement. | Kita D et al. | β | 2026 | β |
| Busulfan resistance in AML is associated with changes in mitochondrial copy number and lipid metabolism. | Mlakar V et al. | β | 2026 | β |
| C9orf72 in myeloid cells prevents an inflammatory response to microbial glycogen. | McCourt B et al. | β | 2026 | β |
| Capturing the Variations in Mutant p53-Driven Regulatory Networks in Breast Cancer Subtypes, Its Clinical Relevance and a Novel Association With Androgen Receptor and EMT. | Singh A et al. | β | 2026 | β |
| Casting the Caspase Activity and Apoptosis Inhibitor 1 Phosphoregulation Through Global Phosphoproteomes. | Sekhar PS et al. | β | 2026 | β |
| CDK12/CDK13 inhibition disrupts transcriptional elongation and replicationΒ fork progression in glioblastoma. | Lier S et al. | β | 2026 | β |
| Cell loss disrupts mechanical homeostasis to drive retinal pigment epithelium ageing-like phenotype in vitro. | Piskova T et al. | β | 2026 | β |
| Cellular and molecular landscapes of human tendons across the lifespan revealed by spatial and single-cell transcriptomics. | Kurjan A et al. | β | 2026 | β |
| Characterization of RNA Editing in Oxidative and Glycolytic Skeletal Muscles of Yak. | Shi Y et al. | β | 2026 | β |
| Characterization of the Proteomic Response in SIM-A9 Murine Microglia Following Canonical NLRP3 Inflammasome Activation. | LafreniΓ¨re NN et al. | β | 2026 | β |
| Comparative proteomic profiling of advanced, injectable, and titanium-prepared platelet rich fibrins (PRF): Insights into functional divergence and clinical potential. | Marimuthu SV et al. | β | 2026 | β |
| Comparative Transcriptomic Profiling Identifies IL-1Ξ² as a Non-Canonical Driver of Human Dendritic Cell Maturation. | Yilmaz V | β | 2026 | β |
| Compound starch granule formation in grass seeds is associated with distinct temporal patterns of gene expression. | Watson-Lazowski A et al. | β | 2026 | β |
| Developmental modulation of schizophrenia risk gene methylation in offspring exhibiting cognitive deficits following maternal immune activation. | Woods RM et al. | β | 2026 | β |
| Differential inclusion formation of an aggregation-prone protein reveals differences in the proteostasis capacity of neuronal cell lines. | McMahon S et al. | β | 2026 | β |
| Digestibility and transcriptomic profiling of kidney, pancreas, follicle, and uterus in laying hens supplemented with phytogenic feed additive. | Reyer H et al. | β | 2026 | β |
| Discovery of parasite proteins in the urine of vivax malaria patients through mass spectrometry. | Tripathi H et al. | β | 2026 | β |
| DNA damage burden causes selective CUX2 neuron loss in neuroinflammation. | Morcom L et al. | β | 2026 | β |
| DNA variants affecting chromatin structure are key to the genetic architecture of obsessive compulsive disorder. | Han VX et al. | β | 2026 | β |
| Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N-ERD Patients. | Eckl-Dorna J et al. | β | 2026 | β |
| Early Transcriptional Changes in Neutrophil-Mediated Processes Following Recanalization After Ischemic Stroke. | Bui TA et al. | β | 2026 | β |
| Endogenous protein tagging coupled with a CRISPR screening approach identifies UBE3C as a potential MYC oncogene regulator. | Seibert M et al. | β | 2026 | β |
| Enhanced myelination potential of human mature oligodendrocytes by TNF and IFNG combination. | Mohammadnia A et al. | β | 2026 | β |
| Exploring potential gene signatures in dengue through machine learning and deep learning approaches. | Josyula JVN et al. | β | 2026 | β |
| Exploring the Functional Consequences of Protein-Coding Alternative Splice Variants at a Genome Scale: A Guide to Utilizing EXPANSION. | Arora C et al. | β | 2026 | β |
| Expression analysis of androglobin and its influence on the transcriptome in cancer. | Osterhof C et al. | β | 2026 | β |
| Functional analysis of O-GlcNAcylation by networking of OGT interactors and substrates. | Griffin ME et al. | β | 2026 | β |
| Functional characterization of a human epilepsy-associated gene network reveals metabolic regulation as a critical factor underlying seizure susceptibilities. | Long J et al. | β | 2026 | β |
| Gene duplication is associated with gene diversification and potential neofunctionalization in lung cancer evolution. | Ashford P et al. | β | 2026 | β |
| Gene Expression as a Guide for the Development of Novel Therapies in Hypertensive and Diabetic Kidney Disease. | Zaimi M et al. | β | 2026 | β |
| Gene regulatory network transitions reveal the central transcription factors in lung adenocarcinoma progression. | Ray U et al. | β | 2026 | β |
| Genetic Diversity, Population Structure and Differentiation of Farmed and Wild African Catfish (<i>Clarias gariepinus</i>) in Nigeria. | Sanda MK et al. | β | 2026 | β |
| Genetic exploration of the relationship between liability to psychiatric disorders and acne vulgaris. | Mitchell BL et al. | β | 2026 | β |
| Genetic insights and mechanistic parallels in gestational diabetes mellitus and type 2 diabetes. | Fu L et al. | β | 2026 | β |
| Germline lung cancer SNPs dysregulate known (LATS1) and novel (ADCY2) oncogenes through distal, spatially-constrained eQTLs. | Khoo A et al. | β | 2026 | β |
| GRNFormer: accurate gene regulatory network inference using graph transformer. | Hegde A et al. | β | 2026 | β |
| Heterochromatin epimutations impose mitochondrial dysfunction to confer antifungal resistance. | Fellas A et al. | β | 2026 | β |
| High glucose in the extender impacts the metabolic phosphoproteome and modifies the phosphorylation of AKAP4 in stallion spermatozoa. | Becerro-Rey L et al. | β | 2026 | β |
| Human-specific lncRNAs contributed critically to human evolution by distinctly regulating gene expression. | Lin J et al. | β | 2026 | β |
| IGF2 supports glioblastoma growth and immune evasion through a combination of tumor cell-intrinsic and -extrinsic mechanisms. | Heemskerk KM et al. | β | 2026 | β |
| Immortalization and characterization of Schwann cell lines derived from NF1-associated cutaneous neurofibromas. | Li H et al. | β | 2026 | β |
| Indian-enriched genetic variants are associated with cognitive function. | Abu-Amara H et al. | β | 2026 | β |
| Inhibition of 15-hydroxy prostaglandin dehydrogenase promotes cartilage regeneration. | Singla M et al. | β | 2026 | β |
| Innate Immune-Cloaked Microgel-Coated Mesenchymal Stromal Cells Reverse Persistent Pulmonary Fibrosis via Reparative Macrophages. | Cho IS et al. | β | 2026 | β |
| InSituPy: a framework for histology-guided, multi-sample analysis of single-cell spatial omics data. | Wirth J et al. | β | 2026 | β |
| Integrated Analysis of the Immune Infiltration Pattern and Novel Diagnostic Biomarkers in Septic Cardiomyopathy. | Liu W et al. | β | 2026 | β |
| Integrated fetal testicular transcriptomic and epigenomic profiles during maternal nutrient restriction with dietary melatonin intervention. | El Daous H et al. | β | 2026 | β |
| Integrated transcriptome analysis of jejunum and liver to identify key genes and pathways associated with body weight in chickens. | Abdel-Kafy EM et al. | β | 2026 | β |
| Integrative Analysis of DNA Methylome and Transcriptome Reveals the Mechanism of Heat Tolerance in Non-heading Chinese Cabbage. | Zhao R et al. | β | 2026 | β |
| Interpretable trajectory inference with single-cell linear adaptive negative-binomial expression (scLANE) testing. | Leary JR et al. | β | 2026 | β |
| Latent tuberculosis infection in high TB disease burden countries dysregulates cellular and immunological profiles which is further enhanced with uncontrolled hyperglycemia. | Masood KI et al. | β | 2026 | β |
| Loss of TRPV1 may shift capsaicin response from MAPK-CASC11-MYC protection to mitochondrial apoptosis in glioblastoma U87 cells. | Chinreddy SR et al. | β | 2026 | β |
| Male-biased Yap1-Cd276/B7-H3 axis for immune evasion in medulloblastoma. | Abdelfattah N et al. | β | 2026 | β |
| Multimodal gene and targeted drug therapy for chronic myelogenous leukemia using BIM/MCL-1 chimeric nanoparticle: computational target analysis and therapeutic validation. | Lugin ML et al. | β | 2026 | β |
| Multimodal quantitative MRI reveals age-related biophysical alterations in the human brain across the adult lifespan. | Chen X et al. | β | 2026 | β |
| Multi-omic identification of key transcriptional regulatory programs during endurance exercise training in rats. | Smith GR et al. | β | 2026 | β |
| Multiomic integration reveals tumoral heterogeneity of lipid dependence within lethal group 3 medulloblastoma. | Bernardi F et al. | β | 2026 | β |
| Multi-platform integration of brain and CSF proteomes reveals biomarker panels for Alzheimer's disease. | Tsai WY et al. | β | 2026 | β |
| Multi-trait genome-wide analysis identified risk loci and candidate drugs for heart failure. | Yu Z et al. | β | 2026 | β |
| Optimizing Single-Cell Long-Read Sequencing for Enhanced Isoform Detection in Pancreatic Islets. | Hansen MS et al. | β | 2026 | β |
| Oral ginger-derived extracellular vesicles ameliorate arthritis via anti-inflammatory actions of microRNA-149 and 6-gingerol. | Kaneta H et al. | β | 2026 | β |
| Pan-neurodegeneration proteomics reveals disease subtypes and molecular signatures. | Shrestha HK et al. | β | 2026 | β |
| Parallel Erosion of a Testis-Specific Na+/K+ ATPase in Three Mammalian Lineages Sheds Light into the Evolution of Spermatozoa Energetics. | Valente R et al. | β | 2026 | β |
| Peptide turnover prediction using transformer architectures on large-scale time-series proteomic data. | Ishino K et al. | β | 2026 | β |
| Phosphoproteome landscape of ARID1A and its implications in DNA damage response and breast cancer pathogenesis. | Kumar APKA et al. | β | 2026 | β |
| Phosphorylation-dependent regulation of Eleven Lysine Rich Leukemia (ELL) uncovered by quantitative global phosphoproteomic analysis. | Kammarambath SR et al. | β | 2026 | β |
| PrePPI - Structure-based Prediction of Protein-protein Interactomes and Networks. | Velez C et al. | β | 2026 | β |
| Progesterone receptor membrane component 1 (PGRMC1) regulates Heme trafficking through mitochondria-ER junctions. | Piel Iii RB et al. | β | 2026 | β |
| Protein-Corona-Based Nanomagnetic Enrichment Strategy for In-Depth Secretome Profiling of Lung Adenocarcinoma Organoids. | Wu W et al. | β | 2026 | β |
| Proteomic Analysis Reveals Accompanying Anion-Dependent Changes of Cadmium Toxicity During Arabidopsis thaliana Development. | LyΔka M et al. | β | 2026 | β |
| Proteomic profiling of bronchoalveolar lavage following human segmental endotoxin challenge-a potential exacerbation model. | Gress C et al. | β | 2026 | β |
| Proteomics-based evaluation of AAV dystrophin gene therapy outcomes in mdx skeletal muscle. | Johnson EE et al. | β | 2026 | β |
| PYRAMA: an open-source tool for advanced meta-analysis of genome wide association studies. | Manios GA et al. | β | 2026 | β |
| (Re)defining the human chromatome: an integrated meta-analysis of localization, function, abundance, physical properties, and domain composition of chromatin proteins. | Gribkova AK et al. | β | 2026 | β |
| Regulatory risk loci link disrupted androgen response to the pathophysiology of polycystic ovary syndrome. | Srivastava J et al. | β | 2026 | β |
| Remote Pancreatic Response to Severe Polytrauma Correlates With Clinical Outcome. | Halbgebauer R et al. | β | 2026 | β |
| RNA-seq at different stages of human pancreatic Ξ² cell differentiation reveals proliferation dynamics and SMAD9 in directing Ξ² cell fate. | Lim EXH et al. | β | 2026 | β |
| Scalable single-cell total RNA sequencing unifies coding and noncoding transcriptomics. | Isakova A et al. | β | 2026 | β |
| scTWAS: a powerful statistical framework for single-cell transcriptome-wide association studies. | Lin Z et al. | β | 2026 | β |
| Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics. | Kumari B et al. | β | 2026 | β |
| Single-cell transcriptomics reveals a differential response of human bronchial epithelial cell-types to cadmium chloride. | Abou Choucha F et al. | β | 2026 | β |
| Sleep-dependent clearance of brain lipids by peripheral blood cells. | Cho B et al. | β | 2026 | β |
| S<sup>2</sup>CIE: semantic, syntactic, and context-based information extraction for AOP development. | Kumar S et al. | β | 2026 | β |
| SNCA triplication disrupts proteostasis and extracellular architecture prior to neurodegeneration in human midbrain organoids. | Statoulla E et al. | β | 2026 | β |
| Spatial transcriptomics of the developing mouse brain immune landscape reveals effects of maternal immune activation and microbiome depletion. | Kukreja B et al. | β | 2026 | β |
| Sustained diabetes remission induced by FGF1 involves a shift in transcriptionally distinct AgRP neuron subpopulations. | Aalling NN et al. | β | 2026 | β |
| Systems genetic dissection of brain gene expression reveals excitotoxic mechanisms of Alzheimer's disease. | Zhao P et al. | β | 2026 | β |
| Tachykinin signaling defines distinct populations of glia in the enteric nervous system. | Muppirala AN et al. | β | 2026 | β |
| Targeting immunometabolic pathways with AZD1656 alleviates inflammation and metabolic dysfunction in type 2 diabetic cardiomyopathy. | Anderson S et al. | β | 2026 | β |
| Temporal Shifts in Gut Microbiota and Host Immunity During Chronic Diarrhea in an Infant Rhesus Macaque: A Longitudinal Case Study Based on Multi-Omics. | Tang R et al. | β | 2026 | β |
| The biomedical landscape of genomic structural variation in the qatari population. | Aliyev E et al. | β | 2026 | β |
| The evolutionary dynamics between viral mimics and host proteins. | Fuchs R et al. | β | 2026 | β |
| The exploration of immunological landscape and drug targets in chronic rhinosinusitis with nasal polyps. | Zhang R et al. | β | 2026 | β |
| The impact of testosterone on paraventricular nucleus gene expression in male and female spontaneously hypertensive rats. | Paterson A et al. | β | 2026 | β |
| The Role of miR-320d in Regulation of Cigarette Smoke-Induced Pro-Inflammatory Responses in COPD. | Roffel MP et al. | β | 2026 | β |
| Time-Dependent Glucocorticoid-Induced Transcriptomic Changes in Human Trabecular Meshwork and Schlemm's Canal Cells. | Mehrotra S et al. | β | 2026 | β |
| Toward a Common Set of Interface Requirements for Genomic Data Management: Scoping Review. | Resendez V et al. | β | 2026 | β |
| UnanchoredΒ K63-linkedΒ polyubiquitinΒ chains: a novel second messenger involved inΒ G protein-coupled receptors early signaling events. | Doyon P et al. | β | 2026 | β |
| Uncovering Key Genes in Neurodegenerative Diseases Through Unsupervised Learning: A Variance-Based LSTM and Enrichment Analysis Approach. | Paplomatas P et al. | β | 2026 | β |
| VΞ³1 Ξ³Ξ΄ T cells steer airway macrophages toward a profibrotic response in an autochthonous lung cancer mouse model. | Raffo-Iraolagoitia XL et al. | β | 2026 | β |
| YAP and TEAD Are Transcriptional Regulators of Neuroendocrine Differentiation and Growth in Carcinoid Cells. | Nanayakkara J et al. | β | 2026 | β |
| ZMYM3 S464: a potential phospho-regulatory hub in epigenetic remodeling and oncogenesis. | Pai A et al. | β | 2026 | β |
| A 3D human iPSC-derived multi-cell type neurosphere system to model cellular responses to chronic amyloidosis. | Wendt S et al. | β | 2025 | β |
| ABCA4-mutant human retinal organoids sequencing reveals organoids application in inherited retinal diseases. | Bao Y et al. | β | 2025 | β |
| Aberrant pace of cortical neuron development in brain organoids from patients with 22q11.2 deletion syndrome-associated schizophrenia. | Rao SB et al. | β | 2025 | β |
| A bipolar disorder-associated missense variant alters adenylyl cyclase 2 activity and promotes mania-like behavior. | Sen P et al. | β | 2025 | β |
| A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer's disease. | Oh HS et al. | β | 2025 | β |
| A chromosome-level, haplotype-resolved genome assembly and annotation for the Eurasian minnow (Leuciscidae: Phoxinus phoxinus) provide evidence of haplotype diversity. | Oriowo TO et al. | β | 2025 | β |
| A collaborative network analysis for the interpretation of transcriptomics data in Huntington's disease. | Ozisik O et al. | β | 2025 | β |
| A comprehensive multi-omics study reveals potential prognostic and diagnostic biomarkers for colorectal cancer. | Mahajan M et al. | β | 2025 | β |
| A contextual genomic perspective on physical activity and its relationship to health, well being and illness. | Galimberti M et al. | β | 2025 | β |
| A Critical Evaluation of Background Gene Omission in Imaging Transcriptomics. | Cao Z et al. | β | 2025 | β |
| ACT2.6: Global Gene Coexpression Network in <i>Arabidopsis thaliana</i> Using WGCNA. | Zogopoulos VL et al. | β | 2025 | β |
| Activation of lands cycle-mediated inflammation in living macrophages exposed to label-free particulate matter. | Park J et al. | β | 2025 | β |
| Acute Shear Stress Induces TWIST-Mediated EndMT in Venous Endothelial Cells and Human Long Saphenous Veins. | Ladak SS et al. | β | 2025 | β |
| Acute toxicity of local anesthetics used for humans and other animals in the larvae of marine crustacean, red-clawed crab Chiromantes haematocheir. | Nishikawa A et al. | β | 2025 | β |
| Addressing hurdles in cultured meat by exploring reduced myogenesis after bovine myoblast expansion. | Olenic M et al. | β | 2025 | β |
| ADGRB1 contributes to astrocyte-mediated phagocytosis of excitatory synapses. | Shiu FH et al. | β | 2025 | β |
| A foundation model of transcription across human cell types. | Fu X et al. | β | 2025 | β |
| Age-impaired remyelination is associated with dysregulated microglial transitions. | Zia S et al. | β | 2025 | β |
| Aggressive serous ovarian cancer subtype defined by high centrality lncRNA profiles and master transcription factors. | Jeong S et al. | β | 2025 | β |
| Aging activates escape of the silent X chromosome in the female mouse hippocampus. | Gadek M et al. | β | 2025 | β |
| Aging-TCA: a cross-species single-cell transcriptomic atlas for studying testicular aging. | Lu Z et al. | β | 2025 | β |
| AI-generated MLH1 small binder improves prime editing efficiency. | Park JC et al. | β | 2025 | β |
| A key role of polyamine metabolism in adipose tissue homeostasis that regulates obesity. | Mund C et al. | β | 2025 | β |
| A KSHV RNA-binding protein promotes FOS to inhibit nuclease AEN and transactivate RGS2 for AKT phosphorylation. | Majerciak V et al. | β | 2025 | β |
| A large-scale sORF screen identifies putative microproteins involved in cancer cell fitness. | Schlesinger D et al. | β | 2025 | β |
| Altered behaviour and immune response in mice with NHLRC2 p.Asp148Tyr variant. | Hiltunen AE et al. | β | 2025 | β |
| Analysis of Population Structure and Selection Signatures in Two Iraqi Fat-Tailed Sheep Breeds. | Bayraktar M et al. | β | 2025 | β |
| An antisense oligonucleotide-based strategy to ameliorate cognitive dysfunction in the 22q11.2 Deletion Syndrome. | Thakur P et al. | β | 2025 | β |
| An Exploratory Study for Proteomic-Based Markers of Joint Pain and Chronic Back Pain. | Schillemans T et al. | β | 2025 | β |
| An Integrated Approach of Proteomic, Cheminformatic, and In Vitro Drug Screening to Identify Potential Therapeutic Targets of <i>Taenia solium</i> Cysticerci Proteases. | Kaur R et al. | β | 2025 | β |
| An integrative systems-biology approach defines mechanisms of Alzheimer's disease neurodegeneration. | Leventhal MJ et al. | β | 2025 | β |
| An in vitro model of the epithelial airway reveals a key function for EHF in lung homeostasis and disease. | Pinte L et al. | β | 2025 | β |
| An RBPMS-driven splicing regulatory axis including MBNL1, RBFOX2, and QK promotes smooth muscle cell contractile identity. | Huang Y et al. | β | 2025 | β |
| Anthracyclines induce global changes in cardiomyocyte chromatin accessibility that overlap with cardiovascular disease loci. | Matthews ER et al. | β | 2025 | β |
| Antibiofilm properties of 4-hydroxy-3-methyl-2-alkenylquinoline, a novel <i>Burkholderia</i>-derived alkaloid. | Williams MD et al. | β | 2025 | β |
| Antibody-lectin chimeras for glyco-immune checkpoint blockade. | Stark JC et al. | β | 2025 | β |
| Anticancer Quinolinol Small Molecules Target Multiple Pathways to Promote Cell Death and Eliminate Melanoma Cells Resistant to BRAF Inhibitors. | Wang X et al. | β | 2025 | β |
| Antigen Cross-Presentation by Type-2 Innate Lymphoid Cells Facilitates the Activation of Antitumor CD8+ T Cells. | Kim J et al. | β | 2025 | β |
| APBIO: bioactive profiling of air pollutants through inferred bioactivity signatures and prediction of novel target interactions. | Viesi E et al. | β | 2025 | β |
| A pre-trained large generative model for translating single-cell transcriptomes to proteomes. | Liu L et al. | β | 2025 | β |
| A Single-Cell Transcriptome Atlas of Epithelial Subpopulations in HPV-Positive and HPV-Negative Head and Neck Cancers. | Bedard MC et al. | β | 2025 | β |
| A single-cell transcriptomic atlas reveals resident dendritic-like cells in the zebrafish brain parenchyma. | Rovira M et al. | β | 2025 | β |
| A spatiotemporal study of a recreational freshwater lake: ultraperformance liquid chromatography-tandem mass spectrometry profiling of cyanotoxins and the dermal toxicity assessment. | Chan VJW et al. | β | 2025 | β |
| Assembly of glioblastoma tumoroids and cerebral organoids: a 3D in vitro model for tumor cell invasion. | Kim J et al. | β | 2025 | β |
| A systematic review and meta-analysis on the transcriptomic signatures in alcohol use disorder. | Friske MM et al. | β | 2025 | β |
| A Systematic Review of Clinical and Experimental Periodontitis Studies Demonstrating the Expression of PPAR-Gamma: A Meta-Analysis and Bioinformatics Approach. | Hidalgo MAR et al. | β | 2025 | β |
| A Systems Biology and Drug Repositioning Approach for the Analysis of Mutual Genes Between Celiac Disease and Irritable Bowel Syndrome. | Al-Madhagi H | β | 2025 | β |
| Attenuated growth factor signaling during cell death initiation sensitizes membranes towards peroxidation. | Gollowitzer A et al. | β | 2025 | β |
| Atypical dynamic neural configuration in autism spectrum disorder and its relationship to gene expression profiles. | Shan X et al. | β | 2025 | β |
| Bat genomes illuminate adaptations to viral tolerance and disease resistance. | Morales AE et al. | β | 2025 | β |
| BBX10 interacts with PIF1 to prevent photo-oxidation and to promote the greening process. | Zhou L et al. | β | 2025 | β |
| bHLH35 mediates specificity in plant responses to multiple stress conditions. | Sinha R et al. | β | 2025 | β |
| BMP3 Deficiency Accelerates Cartilage-to-Bone Transition in Ectopic Bone. | RumenoviΔ V et al. | β | 2025 | β |
| Brain tissue electrical conductivity as a promising biomarker for dementia assessment using MRI. | Chu J et al. | β | 2025 | β |
| Brain-wide cell-type-specific transcriptomic signatures of healthy ageing in mice. | Jin K et al. | β | 2025 | β |
| Brain wiring economics, network organisation and population-level genomics. | Monaghan A et al. | β | 2025 | β |
| Brief exposure to oral antibiotics has age-dependent effects on morphine reward and gene expression in the medial prefrontal cortex of adolescent and adult mice. | Hofford RS et al. | β | 2025 | β |
| Burn Injury Triggers Distinct Transcriptomic Profiles in Adipose Tissue of Adult and Aged Mice. | Bhattachan P et al. | β | 2025 | β |
| C9orf72 hexanucleotide repeat expansions impair microglial response in ALS. | Masrori P et al. | β | 2025 | β |
| Cargo Analysis and MRI-Based Therapeutic Assessment of Iron Oxide Labelled Extracellular Vesicles of Hypoxia Human Stem Cells in Ischemic Stroke. | Helsper S et al. | β | 2025 | β |
| Cataloging copy number variation regions and allied diversity in goat breeds spanning pan India. | Sukhija N et al. | β | 2025 | β |
| catGRANULE 2.0: accurate predictions of liquid-liquid phase separating proteins at single amino acid resolution. | Monti M et al. | β | 2025 | β |
| CDC40 suppression induces CDCA5 splicing defects and anti-proliferative effects in lung cancer cells. | Hu D et al. | β | 2025 | β |
| Cell type-specific 3D-genome organization and transcription regulation in the brain. | Liu S et al. | β | 2025 | β |
| Cell-type-specific dysregulation of gene expression due to Chd8 haploinsufficiency during mouse cortical development. | Yim KM et al. | β | 2025 | β |
| Cellular crosstalk in organotypic vasculature: mechanisms of diabetic cardiorenal complications and SGLT2i responses. | Wang W et al. | β | 2025 | β |
| Characterizing heterologous protein burden in Komagataella phaffii. | Kastberg LB et al. | β | 2025 | β |
| Charting Ξ³-secretase substrates by explainable AI. | Breimann S et al. | β | 2025 | β |
| CHD8 interacts with BCL11A to induce oncogenic transcription in triple negative breast cancer. | Waterhouse M et al. | β | 2025 | β |
| Chronic airway inflammation in <i>Drosophila</i> lacking the A20-like protein Trabid. | Bossen J et al. | β | 2025 | β |
| Chronic arsenic exposure and hsa-miR-186 overexpression causes transcriptome-wide differential alternative splicing contributing to skin carcinogenesis in human HaCaT cell line. | Banerjee M et al. | β | 2025 | β |
| Chronic Larval Exposure to Lambda-Cyhalothrin Alters Gene Expression in Both Larval and Adult Honey Bees (<i>Apis mellifera</i>). | Vasamsetti BMK et al. | β | 2025 | β |
| Circadian rhythmicity and biopsychosocial characteristics influence opioid use in chronic low back pain. | Taccardi D et al. | β | 2025 | β |
| Circulating Proteomic Profiles Are Associated With Incident Type 2 Diabetes in Asian Populations. | Liang Y et al. | β | 2025 | β |
| Clinical Outcomes and Genomic Alterations in Gleason Score 10 Prostate Cancer. | Chen LW et al. | β | 2025 | β |
| Colibactin Exerts Androgen-dependent and -independent Effects on Prostate Cancer. | Agrawal R et al. | β | 2025 | β |
| Colorectal Cancer Biomarker Identification via Joint DNA-Methylation and Transcriptomics Analysis Workflow. | Oladapo OB et al. | β | 2025 | β |
| Comparative analysis of the genomic and expression profiles of ANLN and KDR as prognostic markers in breast Cancer. | Mehmood A et al. | β | 2025 | β |
| Comparative Embryology and Transcriptomics of Asellus infernus, an Isopod Crustacean From Sulfidic Groundwater. | Lomheim HJ et al. | β | 2025 | β |
| Comparative meta-analysis of barely transcriptome: Pathogen type determines host preference. | Soltani Z et al. | β | 2025 | β |
| Comparative Transcriptomic Analysis of <i>Zymoseptoria tritici</i> Reveals Interaction-Specific Gene Expression Patterns During Susceptible, Resistant, and Nonhost Interactions. | Gomez-Gutierrez SV et al. | β | 2025 | β |
| Complementary Strategies to Identify Differentially Expressed Genes in the Choroid Plexus of Patients with Progressive Multiple Sclerosis. | Rodrigues ABM et al. | β | 2025 | β |
| Complete reference genome and pangenome improve genome-wide detection and interpretation of DNA methylation using sequencing and array data. | Dong Z et al. | β | 2025 | β |
| Comprehensive multimodal and multiomic profiling reveals epigenetic and transcriptional reprogramming in lung tumors. | Wu P et al. | β | 2025 | β |
| Comprehensive Multi-omics Analysis of Regulatory Variants for Body Weight in Cattle. | Niu ηηΎ€η Q et al. | β | 2025 | β |
| Comprehensive study of tRNA-derived fragments in plants for biotic stress responses. | Swain SP et al. | β | 2025 | β |
| Comprehensive transposon-insertion profiling unravels the asexual breeding history of sweet orange cultivars. | Wu B et al. | β | 2025 | β |
| Computational design and evaluation of optimal bait sets for scalable proximity proteomics. | Kasmaeifar V et al. | β | 2025 | β |
| Confrontations of the Pathogenic Fungus Colletotrichum graminicola With a Biocontrol Bacterium or a Ubiquitous Fungus Trigger Synthesis of Secondary Metabolites With Lead Structures of Synthetic Fungicides. | Fernando Devasahayam BR et al. | β | 2025 | β |
| Conserved DNA methylation signatures in the prefrontal cortex of female newborn and juvenile guinea pigs following antenatal betamethasone exposure. | Kim B et al. | β | 2025 | β |
| Construction and analysis of a developmental RNA editome in adipose tissue of Ningxiang pigs. | Gao P et al. | β | 2025 | β |
| Convergent Genetic Architecture in Concurrent Anorectal Malformations and Hypospadias: The <i>ESRRA-STARD8</i> Axis as a Key Regulator of Urogenital Development. | Goswami C et al. | β | 2025 | β |
| Coupled transcriptome and proteome analysis of L3 and L4 developmental stages of Anisakis simplex s. s.: insights into target genes under glucose influence. | Polak I et al. | β | 2025 | β |
| Cross-disease transcriptomic meta-analysis and network pharmacology reveal key therapeutic targets in rheumatoid arthritis, systemic lupus erythematosus and multiple sclerosis. | Lakshmi K et al. | β | 2025 | β |
| Cross-species and cross-platform analysis reveals the application value of guinea pig retina in myopia research at single-cell resolution. | Chen M et al. | β | 2025 | β |
| Data-Independent Acquisition Analysis to Identify Serum Biomarkers and Neoantigens for Differentiating Colorectal Cancer from Inflammatory Bowel Diseases. | Rai AB et al. | β | 2025 | β |
| Deciphering the effect of UM171 on human hematopoietic progenitor cell fate through clonal analysis. | Coulombe P et al. | β | 2025 | β |
| Deciphering the prognostic landscape of triple-negative breast cancer: A focus on immune-related hub genes and therapeutic implications. | Krishnamoorthy HR et al. | β | 2025 | β |
| Decoding Cervical Cancer Biomarkers: An Integrated Framework of Bioinformatics, Machine Learning, and Experimental Confirmation. | Kamble P et al. | β | 2025 | β |
| Defective Olfactomedin-2 connects adipocyte dysfunction to obesity. | Lluch A et al. | β | 2025 | β |
| Deficiency of the Synaptic Adhesion Protein Leucine-Rich Repeat Transmembrane Protein 4 Like 1 Affects Anxiety and Aggression in Zebrafish. | Tatzl E et al. | β | 2025 | β |
| Denosumab Enhances Antitumor Immunity by Suppressing SPP1 and Boosting Cytotoxic T Cells. | Su Z et al. | β | 2025 | β |
| De novo SSR markers development and genetic diversity assessment in <i>Ailanthus excelsa</i> in India. | Kant R et al. | β | 2025 | β |
| Deployment and transcriptional evaluation of nitisinone, an FDA-approved drug, to control bed bugs. | Sterkel M et al. | β | 2025 | β |
| Derivation of functional neurons from induced pluripotent stem cells using a simple neuromesodermal progenitor generation and rapid spinal cord neuron differentiation process. | Εenkal-Turhan S et al. | β | 2025 | β |
| Development and evaluation of S-carboxymethyl-L-cystine-loaded solid lipid nanoparticles for Parkinson's disease in murine and zebrafish models. | Almeida SD et al. | β | 2025 | β |
| Development of an in vitro method to assess the immunogenicity of biologics in the prevention of infectious diseases. | Baran J et al. | β | 2025 | β |
| Diet-induced obesity disrupts sexually dimorphic gene expression in mice. | Ribas V et al. | β | 2025 | β |
| Differential Gene Analysis of Langerhans Cell Histiocytosis and the Significance of MMP1-Targeted Drug Repositioning. | Feng X et al. | β | 2025 | β |
| Differential impact of hepatitis delta virus replication and expression of viral antigens on the cellular kinome profile. | Thiyagarajah K et al. | β | 2025 | β |
| Differential Transpiration of Soybean Plants Subjected to a Combination of Water Deficit and Heat Stress Under Field Conditions. | Sinha R et al. | β | 2025 | β |
| DIS3L, cytoplasmic exosome catalytic subunit, is essential for development but not cell viability in mice. | Brouze M et al. | β | 2025 | β |
| Discriminating activating, deactivating and resistance variants in protein kinases. | Singh G et al. | β | 2025 | β |
| Disruption of the cerebrospinal fluid-plasma protein balance in cognitive impairment and aging. | Farinas A et al. | β | 2025 | β |
| Distinct Co-methylation Patterns in African and European Populations and Their Genetic Associations. | Dong Z et al. | β | 2025 | β |
| Distinct immune responses to proton and photon radiotherapy: implications for anti-PD-L1 combination therapy in colorectal cancer. | Burckel H et al. | β | 2025 | β |
| Distinct transcriptional alterations distinguish Lewy body disease from Alzheimer's disease. | Olney KC et al. | β | 2025 | β |
| Diurnal rhythms in durum wheat triggered by Rhopalosiphum padi (bird cherry-oat aphid). | Goldstein Y et al. | β | 2025 | β |
| Divergence in Regulatory Regions and Gene Duplications May Underlie Chronobiological Adaptation in Desert Tortoises. | Mellor NJ et al. | β | 2025 | β |
| Drought-responsive transcriptional regulations and expressional marker genes of Japanese cedar, Cryptomeria japonica (L.f.) D. Don. | Nagano S et al. | β | 2025 | β |
| Dual Inhibition of SRC Family Kinases and Sorafenib Enhances Anti-Tumor Activity in Hepatocellular Carcinoma Cells. | Cabral LK et al. | β | 2025 | β |
| Dynamic clustering of genomics cohorts beyond race, ethnicity-and ancestry. | Mohsen H et al. | β | 2025 | β |
| Dynamic Proteome Landscape During Preimplantation Human Embryo Development and Trophectoderm Stem Cell-Differentiation. | Rai A et al. | β | 2025 | β |
| Dynamics of transcriptional programs and chromatin accessibility in mouse spermatogonial cells from early postnatal to adult life. | Lazar-Contes I et al. | β | 2025 | β |
| Dysregulation of Retinal and Photoreceptor Structural Integrity Genes in ATF6<sup>-/-</sup> Retinal Organoids. | Bradley A et al. | β | 2025 | β |
| Early adipose tissue wasting in a preclinical model of human lung cancer cachexia. | Snoke DB et al. | β | 2025 | β |
| Early downregulation of hair cell (HC)-specific genes in the vestibular sensory epithelium during chronic ototoxicity. | Borrajo M et al. | β | 2025 | β |
| Effects of directly printed aligner eluent on the viability and transcriptome of gingival fibroblasts. | Kim HY et al. | β | 2025 | β |
| Effects of environmental salinity on global and endocrine-specific transcriptomic profiles in the caudal neurosecretory system of salmonid fishes. | Culbert BM et al. | β | 2025 | β |
| Enhanced Functionality of Anti-GPC3 CAR-T Cells Against Hepatocellular Carcinoma Through Locoregional Administration. | Wang J et al. | β | 2025 | β |
| Enhancing cancer subtype classification through convolutional neural networks: a deepinsight analysis of TCGA gene expression data. | Li C et al. | β | 2025 | β |
| EnrichKit: a multi-omics tool for livestock research. | Liu L et al. | β | 2025 | β |
| Epizootic shell disease induces systemic transcriptomic shifts in <i>Homarus americanus</i>, characterized by increased shell degradation and impaired energy metabolism across tissues. | Kim M et al. | β | 2025 | β |
| Evaluating the role of alveolar macrophages in tolerance to ozone. | Smith GJ et al. | β | 2025 | β |
| Evaluation of miR-27a-5p and miR-449a as potential serum biomarkers for breast cancer: a combined bioinformatics and experimental study. | Barati T et al. | β | 2025 | β |
| Evidence for divergent cortical organisation in Parkinson's disease and Lewy Body Dementia. | Zarkali A et al. | β | 2025 | β |
| Evolutionary divergence of induced versus constitutive antiviral gene expression levels between primates and rodents. | Schneor L et al. | β | 2025 | β |
| Exogenous bacterial cellulose induces plant tissue regeneration through the regulation of cytokinin and defense networks. | Ruiz-SolanΓ N et al. | β | 2025 | β |
| Expanding the Knowledge of the Molecular Effects and Therapeutic Potential of Incomptine A for the Treatment of Non-Hodgkin Lymphoma: In Vivo and Bioinformatics Studies, Part III. | GarcΓa-HernΓ‘ndez N et al. | β | 2025 | β |
| Exploring Genetic Influences on Equine Meat Quality: A Bioinformatics Approach. | Ε imon M et al. | β | 2025 | β |
| Exploring the landscape of Parkinson's disease transcriptomics: a quantitative review of research progress and future directions. | Wang Y et al. | β | 2025 | β |
| Exploring the Mechanism of Action of Berberine on Arrhythmia After Myocardial Infarction: A Network Pharmacology, Molecular Docking, and Cellular Experimental Study. | Haitian-Li et al. | β | 2025 | β |
| Exploring the Skin Benefits of Extremophilic Postbiotics from <i>Exiguobacterium artemiae</i>: A New Frontier in Thermal Protection. | Lee H et al. | β | 2025 | β |
| Exploring the Therapeutic Potential of <i>Moringa oleifera</i> Against Lung Cancer Through Network Modeling and Molecular Docking Analysis. | Singh A et al. | β | 2025 | β |
| Ferroptosis-Linked Six-Gene Panel Enables Machine Learning-Assisted Diagnosis and Therapeutic Guidance in Lung Adenocarcinoma. | Alrumaihi F | β | 2025 | β |
| FGF13 Regulates VGSC-Independent Cardiomyocyte Impulse Propagation via Cx43 Trafficking. | Das LT et al. | β | 2025 | β |
| Fire ant ovary gene expression analyses revealed immune and insulin pathways underlie the reproductive transition from virgin to mated queen. | Ferreira TN et al. | β | 2025 | β |
| Flavopiridol restores granulopoiesis in experimental models of severe congenital neutropenia. | Nasri M et al. | β | 2025 | β |
| Fluctuating DNA methylation tracks cancer evolution at clinical scale. | Gabbutt C et al. | β | 2025 | β |
| From risk to chronicity: genetic and neuroimaging insights into the evolving patterns of spontaneous brain activity in schizophrenia. | Zhang Y et al. | β | 2025 | β |
| Functional analysis across model systems implicates ribosomal proteins in growth and proliferation defects associated with hypoplastic left heart syndrome. | Nielsen T et al. | β | 2025 | β |
| Functional tendon regeneration is driven by regulatory T cells and IL-33 signaling. | Arvind V et al. | β | 2025 | β |
| GeneCOCOA: Detecting context-specific functions of individual genes using co-expression data. | Zehr S et al. | β | 2025 | β |
| Gene Expression Correlates with Disability and Pain Intensity in Patients with Chronic Low Back Pain and Modic Changes in a Sex-Specific Manner. | Vigeland MD et al. | β | 2025 | β |
| Genetic correlation, pleiotropic loci and shared risk genes between major depressive disorder and gastrointestinal tract disorders. | Zhou S et al. | β | 2025 | β |
| Genetic dissection of the root system architecture QTLome and its relationship with early shoot development, breeding and adaptation in durum wheat. | Sciara G et al. | β | 2025 | β |
| Genetic diversity and selection signatures in sheep breeds. | Rodrigues JL et al. | β | 2025 | β |
| Genetic modulation of rare earth nanoparticle biotransformation shapes biological outcomes. | Tian M et al. | β | 2025 | β |
| Genetic neurodevelopmental clustering and dyslexia. | Ciulkinyte A et al. | β | 2025 | β |
| Genome-wide association studies of the fatty acid composition of Korean native chicken breast meat. | Munyaneza JP et al. | β | 2025 | β |
| Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes. | Henry A et al. | β | 2025 | β |
| Genome-wide association study of Fuchs' endothelial corneal dystrophy in the German population. | Fechner J et al. | β | 2025 | β |
| Genome-wide characterization and seasonal modulation of Hsp60 expression in juvenile Hilsa Shad across distinct upstream habitats. | Hossain Aunkor MT et al. | β | 2025 | β |
| Genome-wide identification of modulators of Chlamydia trachomatis parasitophorous vacuole stability highlights an important role for sphingolipid supply. | Babu Sait MR et al. | β | 2025 | β |
| Genome-Wide Inference of Essential Genes in <i>Dirofilaria immitis</i> Using Machine Learning. | Campos TL et al. | β | 2025 | β |
| Genome-wide patterns of local adaptation associated with transposable elements in Tetrastigma hemsleyanum (Vitaceae). | Ren C et al. | β | 2025 | β |
| Genome-Wide Scans for Selection Signatures in Haimen Goats Reveal Candidate Genes Associated with Growth Traits. | Zhang Z et al. | β | 2025 | β |
| Genomic insights into growth traits in German Black Pied cattle: a dual-purpose breed at risk. | KorkuΔ P et al. | β | 2025 | β |
| Genomic insights into racing camels: inbreeding levels and positive selection linked to athletic traits. | Bahbahani H et al. | β | 2025 | β |
| Genomics-driven integrative analysis highlights immune-related plasma proteins for psychiatric disorders. | Gong W et al. | β | 2025 | β |
| Genomic signatures associated with recurrent scale loss in cyprinid fish. | Ding Y et al. | β | 2025 | β |
| Genomic signatures of adaptation in native lizards exposed to human-introduced fire ants. | Assis BA et al. | β | 2025 | β |
| Geographic Variation in Epigenetic Responses to Hypoxia in Deer Mice (Peromyscus maniculatus) Distributed Along an Elevational Gradient. | Tandon D et al. | β | 2025 | β |
| Germline Sequencing of Familial and Sporadic Early-Onset Colorectal Cancer: A Novel Pattern of Genes. | Vande Perre P et al. | β | 2025 | β |
| GFAP mutation and astrocyte dysfunction lead to a neurodegenerative profile with impaired synaptic plasticity and cognitive deficits in a rat model of Alexander disease. | Berman RF et al. | β | 2025 | β |
| GhLPF1 Associated Network Is Involved with Cotton Lint Percentage Regulation Revealed by the Integrative Analysis of Spatial Transcriptome. | Wu H et al. | β | 2025 | β |
| Global analysis of actionable genomic alterations in thyroid cancer and precision-based pharmacogenomic strategies. | Espinoza-Ferrao S et al. | β | 2025 | β |
| Global mapping of RNA N<sup>6</sup>-methyladenosine (m<sup>6</sup>A) in human subcutaneous and visceral adipose tissue reveals novel targets that correlate with clinical variables of obesity. | RΓΈnningen T et al. | β | 2025 | β |
| Glycine-to-aspartic acid mutation at codon 51 in <i>Snca</i> disrupts the synaptic localisation of Ξ±-synuclein and enhances its propensity for synucleinopathy. | West S et al. | β | 2025 | β |
| Gut microbiota and osteonecrosis: A Mendelian randomization study. | Cai Y et al. | β | 2025 | β |
| Haploid-Phased Chromosomal Telomere-to-Telomere Genome Assembly of Medicinal Plant Uncaria rhynchophylla Dissects Genetic Controls on the Biosynthesis of Bioactive Alkaloids. | Hu T et al. | β | 2025 | β |
| HCCS Serves as Potential Prognostic Biomarker and Therapeutic Target in Human Breast Cancer. | Bellah SF et al. | β | 2025 | β |
| Heat shock induces alternative polyadenylation through dynamic DNA methylation and chromatin looping. | Fink EE et al. | β | 2025 | β |
| High-glucose diets differentially modulate phosphatidylcholine metabolism and fecundity in <i>Caenorhabditis elegans</i>. | Wang CW et al. | β | 2025 | β |
| Hotspots of human mutation point to clonal expansions in spermatogonia. | Seplyarskiy V et al. | β | 2025 | β |
| HSV-1 infection induces a downstream shift of the +1 nucleosome. | WeiΓ E et al. | β | 2025 | β |
| Human neural rosettes secrete bioactive extracellular vesicles enriched in neuronal and glial cellular components. | Herrera Lopez M et al. | β | 2025 | β |
| Hypoxia in extravillous trophoblasts links maternal obesity and offspring neurobehavior. | Gunter-Rahman F et al. | β | 2025 | β |
| Identification and Characterization of Key Genes Associated with Amelogenesis. | Haque T et al. | β | 2025 | β |
| Identification of Gene Targets for the Sprouting Inhibitor CIPC. | Grand TM et al. | β | 2025 | β |
| Identification of immune signatures associated with both SARS-CoV-2 infection and lung transplantation. | Hoffmann AD et al. | β | 2025 | β |
| Identification of Metabolic Pathways and Hub Genes Associated with Ultrasound Subcutaneous Fat and Muscle Depth of the Longissimus Muscle in Cull Beef Cows Using Gene Co-Expression Analysis. | Shinde H et al. | β | 2025 | β |
| Identification of novel MYO19 variants in neonatal hypertrophic cardiomyopathy: a familial analysis revealing oligogenic contributors to disease severity. | Cho HW et al. | β | 2025 | β |
| Identification of novel xanthine oxidase inhibitory peptides from Takifugu obscurus: Peptidomic analysis, molecular docking, and dynamics simulation. | Yang B et al. | β | 2025 | β |
| Identification of plasma proteomic markers underlying polygenic risk of type 2 diabetes and related comorbidities. | Loesch DP et al. | β | 2025 | β |
| Identifying genetic overlaps in obesity and metabolic disorders unlocking unique and shared mechanistic insights. | Fu L et al. | β | 2025 | β |
| Impact of Copper Nanoparticles on Keratin 19 (KRT19) Gene Expression in Breast Cancer Subtypes: Integrating Experimental and Bioinformatics Approaches. | Taha S et al. | β | 2025 | β |
| Impact of diabetes on proteomic changes in circulating extracellular vesicles in individuals with obesity before and after bariatric surgery. | Lee H et al. | β | 2025 | β |
| Impact of Sample Preparation Strategies on the Quantitative Accuracy of Low-Abundance Serum Proteins in Shotgun Proteomics. | Katsavelis D et al. | β | 2025 | β |
| Improving genetic variant identification for quantitative traits using ensemble learning-based approaches. | Sharma J et al. | β | 2025 | β |
| ImSpiRE: image feature-aided spatial resolution enhancement method. | Hua Y et al. | β | 2025 | β |
| Influenza virus-induced type I interferons disrupt alveolar epithelial repair and tight junction integrity in the developing lung. | Onufer AP et al. | β | 2025 | β |
| Inherited Genetic Variation in Parkinson's Disease: Convergence on Impaired Autophagosome-Lysosome Fusion Through the Altered Expression of mRNA Isoforms. | Gokuladhas S et al. | β | 2025 | β |
| Insights into Convergent Evolution From Studying Amino Acid Patterns in Independent Lineages of Birds. | Lee C et al. | β | 2025 | β |
| Insights of <i>Phaseolus vulgaris</i>' response to infection by <i>Uromyces appendiculatus</i> using an RNA-seq approach. | Makhumbila P et al. | β | 2025 | β |
| In silico and experimental analysis of ribosomal proteins expressions in SARS-cov-2 patients. | Vafanezhad F et al. | β | 2025 | β |
| Insufficiency of 40S ribosomal proteins, RPS26 and RPS25, negatively affects biosynthesis of polyglycine-containing proteins in fragile-X associated conditions. | Tutak K et al. | β | 2025 | β |
| Integrated network pharmacology and in vivo experimental approaches unveil the modulatory effect of telmisartan on autophagy in a rat model of nonalcoholic steatohepatitis. | Metwally SS et al. | β | 2025 | β |
| Integrated network propagation identifies prognostic metabolic signatures in acute myeloid leukemia. | Song JK et al. | β | 2025 | β |
| Integrated omics reveals disease-associated radial glia-like cells with epigenetically dysregulated interferon response in multiple sclerosis. | Park B et al. | β | 2025 | β |
| Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder. | Green NC et al. | β | 2025 | β |
| Integrated Transcriptome and Metabolome Insights Into Floral Buds Fertility and Adaptive Mechanisms Under Long-Term Thermal Stress in Brassica napus L. | Mackon E et al. | β | 2025 | β |
| Integrated Transcriptomics and Metabolomics Studies Reveal Steroid Biosynthesis Pathway and BCL2 Inhibitory Diazo-progesterone of <i>Drimia indica</i> for Conservation and Sustainable Utilization. | Shit V et al. | β | 2025 | β |
| Integrating rare pathogenic variant prioritization with gene-based association analysis to identify novel genes and relevant multimodal traits for Alzheimer's disease. | Cao J et al. | β | 2025 | β |
| Integrating thermal proteome profiling and virtual screening to reveal the mechanism of Bletilla striata against osteoclast-driven osteoporosis. | Dai G et al. | β | 2025 | β |
| Integration of multi-omics and crowdsourcing assessment of placenta-brain axis biomarkers for predicting neurodevelopmental disorders. | Zhang Y et al. | β | 2025 | β |
| Integrative computational and experimental validation of Piperlongumine as a therapeutic agent targeting differentially expressed genes in colorectal cancer. | Sahoo RK et al. | β | 2025 | β |
| Integrative Genomics Refines Tissues, Candidate Genes and Putative Regulatory Links Involved in the Humic Adaptation of Keystone Freshwater Fish. | Ozerov MY et al. | β | 2025 | β |
| Integrative genomics sheds light on the immunogenetics of tuberculosis in cattle. | O'Grady JF et al. | β | 2025 | β |
| Integrative multi-omics analysis of autism spectrum disorder reveals unique microbial macromolecules interactions. | Osama A et al. | β | 2025 | β |
| Intergenerational effects of maternal rate of body weight gain on the multi-omics hepatic profiles of bovine fetuses. | Anas M et al. | β | 2025 | β |
| Intestinal fibroblast heterogeneity - unifying RNA-seq studies and introducing consensus-driven nomenclature. | Glisovic N et al. | β | 2025 | β |
| Introduction of epigenetic variation contribute to resistance against the human parasite Schistosoma mansoni. | Luviano-Aparicio N et al. | β | 2025 | β |
| Investigating neutrophil responses to stimuli: Comparative analysis of reactive species-dependent and independent mechanisms. | Reis LR et al. | β | 2025 | β |
| Investigating shared genetic architecture between major depressive disorder and central obesity. | Zhan Y et al. | β | 2025 | β |
| In vitro derivation of midbrain dopaminergic neurons from porcine embryonic stem cells in multi-dimensional conditions. | Choi H et al. | β | 2025 | β |
| In vivo AAV-SB-CRISPR screens of tumor-infiltrating primary NK cells identify genetic checkpoints of CAR-NK therapy. | Peng L et al. | β | 2025 | β |
| In Vivo MicroRNA-Based Inhibition of Experimental Cestode Infection. | Grecco A et al. | β | 2025 | β |
| irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein assemblies on RNA. | Ducoli L et al. | β | 2025 | β |
| ITLN1 exacerbates Crohn's colitis by driving ZBP1-dependent PANoptosis in intestinal epithelial cells through antagonizing TRIM8-mediated CAPN2 ubiquitination. | Zhao J et al. | β | 2025 | β |
| Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations. | Kobren SN et al. | β | 2025 | β |
| KNUTS-DB - a data-driven knowledge database for NUTS. | Kemmler E et al. | β | 2025 | β |
| Lactobacillus salivarius HHuMin-U attenuates vulvovaginal candidiasis via vaginal epithelial immune enhancement mediated by NF-ΞΊB activation. | Choi J et al. | β | 2025 | β |
| Lagging Brain Gene Expression Patterns of Drosophila melanogaster Young Adult Males Confound Comparisons Between Sexes. | McLamb F et al. | β | 2025 | β |
| Lifting regenerative barriers promotes epithelial cell fate plasticity supporting lineage conversion. | Bejar MT et al. | β | 2025 | β |
| Linear ubiquitination prevents lipodystrophy and obesity-associated metabolic syndrome. | Hildebrandt X et al. | β | 2025 | β |
| Liver-X receptor Ξ²-selective agonist CE9A215 regulates Alzheimer's disease-associated pathology in a 3xTg-AD mouse model. | Ban SY et al. | β | 2025 | β |
| Longitudinal serum proteome mapping reveals biomarkers for healthy ageing and related cardiometabolic diseases. | Tang J et al. | β | 2025 | β |
| Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos. | Hartley A et al. | β | 2025 | β |
| Loss-of-function variants of CYP706A3 in two natural accessions of Arabidopsis thaliana increase floral sesquiterpene emission. | Kang M et al. | β | 2025 | β |
| Loss of peptidylarginine deiminase 4 mitigates maladaptive cardiac remodeling after myocardial infarction through inhibition of inflammatory and profibrotic pathways. | Holthaus M et al. | β | 2025 | β |
| Low-Coverage Whole-Genome Analysis of Population Structure, Bottlenecks, and Selection in Indiana Bats Before and After White-Nose Syndrome. | Kwait R et al. | β | 2025 | β |
| Lymphovascular Invasion Is Associated With Doxorubicin Resistance inΒ Breast Cancer. | Corachea AJM et al. | β | 2025 | β |
| MAC3A and MAC3B Modulate FLOWERING LOCUS M Splicing to Repress Photoperiod-Dependent Floral Transition. | Huang YW et al. | β | 2025 | β |
| Macrophage memory emerges from coordinated transcription factor and chromatin dynamics. | Wang AG et al. | β | 2025 | β |
| Maintaining breed integrity: Successful introgression of the SLICK1 allele into the Holstein breed. | Zayas GA et al. | β | 2025 | β |
| Mapping cancer gene dynamics through state-specific interactions. | Maqueda-Real A et al. | β | 2025 | β |
| Mapping chromatin remodelling in glioblastoma identifies epigenetic regulation of key molecular pathways and novel druggable targets. | Vinel C et al. | β | 2025 | β |
| Mapping <i>C. difficile</i> TcdB interactions with host cell-surface and intracellular factors using proximity-dependent biotinylation labeling. | Ward JS et al. | β | 2025 | β |
| Maternal Melatonin Supplementation Modulates Placental DNA Methylation and Gene Expression in Nutrient-Restricted Cattle. | Rajput S et al. | β | 2025 | β |
| Maternal Ξ±-casein deficiency extends the lifespan of offspring and programmes their body composition. | Kolb AF et al. | β | 2025 | β |
| Mendelian randomization and genetic pleiotropy analysis for the connection between inflammatory bowel disease and Alzheimer's disease. | Wu Y et al. | β | 2025 | β |
| Menopause-induced 17Ξ²-estradiol and progesterone loss increases senescence markers, matrix disassembly and degeneration in mouse cartilage. | Gilmer G et al. | β | 2025 | β |
| Meta-analysis of activated neurons reveals dynamic regulation of diverse classes of alternative splicing. | Krick KS et al. | β | 2025 | β |
| Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases. | Roselli C et al. | β | 2025 | β |
| Metabolite Genome-Wide Association in Hispanics with Obesity Reveals Genetic Risk and Interactions with Dietary Factors for Type 2 Diabetes. | Lai CQ et al. | β | 2025 | β |
| Metagenome-informed metaproteomics of the human gut microbiome, host, and dietary exposome uncovers signatures of health and inflammatory bowel disease. | ValdΓ©s-Mas R et al. | β | 2025 | β |
| Metagenomic and proteomic analyses reveal similar reproductive microbial profiles and shared functional pathways in uterine immune regulation in mares and jennies. | da Silva-Γlvarez E et al. | β | 2025 | β |
| Microglia dysfunction, neurovascular inflammation and focal neuropathologies are linked to IL-1- and IL-6-related systemic inflammation in COVID-19. | Fekete R et al. | β | 2025 | β |
| Microglial NLRP3-gasdermin D activation impairs blood-brain barrier integrity through interleukin-1Ξ²-independent neutrophil chemotaxis upon peripheral inflammation in mice. | Yoon SH et al. | β | 2025 | β |
| mimicINT: A workflow for microbe-host protein interaction inference. | Choteau SA et al. | β | 2025 | β |
| miR-449a/miR-340 reprogram cell identity and metabolism in fusion-negative rhabdomyosarcoma. | Pozzo E et al. | β | 2025 | β |
| MiR-7 inhibits progression of glioblastoma by impairing autophagy resolution, energy metabolism and ECM remodeling. | Torrecilla-Parra M et al. | β | 2025 | β |
| miRNA biomarkers to predict risk of primary non-function of fatty allografts and drug induced acute liver failures. | SchΓΆnberg J et al. | β | 2025 | β |
| MixOmics Integration of Biological Datasets Identifies Highly Correlated Variables of COVID-19 Severity. | Harriott NC et al. | β | 2025 | β |
| Modified human mesenchymal stromal/stem cells restore cortical excitability after focal ischemic stroke in rats. | Klein B et al. | β | 2025 | β |
| MOGEDN: small-sample cancer subtype classification with encoder-decoder networks for missing-omics recovery and biomarker discovery. | Jin D et al. | β | 2025 | β |
| Molecular and developmental deficits in Smith-Magenis syndrome human stem cell-derived cortical neural models. | Lee YJ et al. | β | 2025 | β |
| Motor Functional Hierarchical Organization of Cerebrum and Its Underlying Genetic Architecture in Parkinson's Disease. | Bu S et al. | β | 2025 | β |
| MT2 receptor mediates melatonin-induced thermogenic program in human myoblasts: insights for circadian syndrome and diabesity treatment. | Salagre D et al. | β | 2025 | β |
| Multi-Ancestry Transcriptome-Wide Association Studies of Cognitive Function, White Matter Hyperintensity, and Alzheimer's Disease. | Chaar DL et al. | β | 2025 | β |
| Multi-omic and spatial analysis of mouse kidneys highlights sex-specific differences in gene regulation across the lifespan. | Chen S et al. | β | 2025 | β |
| Multi-omic profiles of Sorghum genotypes with contrasting heat tolerance connect pathways related to thermotolerance. | Watson-Lazowski A et al. | β | 2025 | β |
| Multiomic profiling reveals that prostaglandin E2 reverses aged muscle stem cell dysfunction, leading to increased regeneration and strength. | Wang YX et al. | β | 2025 | β |
| Multi-omics analysis of SFTS virus infection in Rhipicephalus microplus cells reveals antiviral tick factors. | Petit MJ et al. | β | 2025 | β |
| Multi-Omics Analysis of the Epigenetic Effects of Inflammation in Murine Type II Pneumocytes. | Fernandez JA et al. | β | 2025 | β |
| Multi-omics analysis reveals molecular and biochemical mechanisms underlying alkaline stress adaptation in Solanum lycopersicum L. | Ganasula BK et al. | β | 2025 | β |
| Multi-omics integration analysis reveals the regulatory impact of CNVs for slaughter traits in cattle. | Wu J et al. | β | 2025 | β |
| Multi-omics investigation of spontaneous T2DM macaque emphasizes gut microbiota could up-regulate the absorption of excess palmitic acid in the T2DM progression. | Liu X et al. | β | 2025 | β |
| Multiomics unravels the complexity of male obesity: a prospective observational study. | Papadakis GE et al. | β | 2025 | β |
| Multiple genomic ancestries in the broom hare mark the complex biogeographic history of hares in the Iberian Peninsula. | Souto J et al. | β | 2025 | β |
| Multiple strategies association revealed functional candidate FASN gene for fatty acid composition in cattle. | Zhu B et al. | β | 2025 | β |
| Multi-tissue transcriptome-wide association study identifies novel candidate genes and pleiotropy effects across four abdominal hernia subtypes. | Chaar DL et al. | β | 2025 | β |
| Multi-trait GWAS for growth under contrasting thermal rearing conditions in rainbow trout (Oncorhynchus mykiss). | Gallardo-Hidalgo J et al. | β | 2025 | β |
| Mutations in unfolded protein response regulator ATF6 cause hearing and vision loss syndrome. | Lee EJ et al. | β | 2025 | β |
| MYB74 transcription factor guides de novo specification of epidermal cells in the abscission zone of Arabidopsis. | Wen X et al. | β | 2025 | β |
| Myelin-axon interface vulnerability in Alzheimer's disease revealed by subcellular proteomics and imaging of human and mouse brain. | Cai Y et al. | β | 2025 | β |
| Nanobioreactor detection of space-associated hematopoietic stem and progenitor cell aging. | Pham J et al. | β | 2025 | β |
| Natural genetic variation quantitatively regulates heart rate and dimension. | Gierten J et al. | β | 2025 | β |
| Neocortical tau propagation is a mediator of clinical heterogeneity in Alzheimer's disease. | Chongtham A et al. | β | 2025 | β |
| Network-based insights into miR-30a-5p-mediated regulation and EGCG targeting in triple-negative breast cancer. | Dharshini LCP et al. | β | 2025 | β |
| Neural crest cell recruitment and reprogramming as central drivers of embryonic limb regeneration. | Laplace-BuilhΓ© B et al. | β | 2025 | β |
| Neural Plasticity Induced by Working Memory Training: Insights From Cortical Microstructure and Transcriptional Profiles. | Zhang T et al. | β | 2025 | β |
| Noncoding rare variant associations with blood traits in 166,740 UK Biobank genomes. | Ribeiro DM et al. | β | 2025 | β |
| O-GlcNAcylation of NONO regulates paraspeckle component assembly and contributes to colon cancer cell proliferation. | Kim Y et al. | β | 2025 | β |
| Osteoblast-Derived Mitochondria Formulated with Cationic Liposome Guide Mesenchymal Stem Cells into Osteogenic Differentiation. | Kim HR et al. | β | 2025 | β |
| Parent-of-origin effects of phosphatidyl inositol-bisphosphate hydrolysis pathway genes on type 2 diabetes and the modification effect by obesity. | Tan Y et al. | β | 2025 | β |
| Peer victimization in adolescence alters gene expression and cytokine profiles during transition to adulthood. | Heumann J et al. | β | 2025 | β |
| Persistent myeloid cell reprogramming despite miltefosine treatment in leishmania-infected macaques. | Picard M et al. | β | 2025 | β |
| PGC1Ξ±Β regulates the mitochondrial metabolism response to cyclic stretch, which inhibits neointimal hyperplasia. | Zou M et al. | β | 2025 | β |
| Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity. | Granda Farias A et al. | β | 2025 | β |
| Phloem-specific translational regulation of soybean nodulation: Insights from a phloem-targeted TRAP-seq approach. | Song JH et al. | β | 2025 | β |
| Phosphoproteomic identification of Mos-MAPK targets in meiotic cell cycle and asymmetric oocyte divisions. | Avilov I et al. | β | 2025 | β |
| Photo-proximity labeling in live primary neurons identifies an AMPA-receptor signal transducer in homeostatic synaptic plasticity. | Basu A et al. | β | 2025 | β |
| Piglet birth weight but not the timing of zinc supplementation in gestation diets affects tissue mineral concentrations and gene expression. | Hammers KL et al. | β | 2025 | β |
| Placental transcriptomic profiling showed disturbance of chemokine activities and lymphocyte chemotaxis in pregnancy with fetal growth restriction. | Li X et al. | β | 2025 | β |
| Plant response to intermittent heat stress involves modulation of mRNA translation efficiency. | Dannfald A et al. | β | 2025 | β |
| Plasma-based brain age as a potential biomarker for cognitive health and risk of brain-related disorders. | Wang B et al. | β | 2025 | β |
| Plasma proteomic profiles reveal proteins and three characteristic patterns associated with osteoporosis: A prospective cohort study. | Zheng Y et al. | β | 2025 | β |
| Plasma proteomics links brain and immune system aging with healthspan and longevity. | Oh HS et al. | β | 2025 | β |
| Polyadenylation landscape of in vivo long-term potentiation in the rat brain. | GumiΕska N et al. | β | 2025 | β |
| Polygenic pathways shape white matter vulnerability to Alzheimer's disease-related pathophysiological changes. | Tranfa M et al. | β | 2025 | β |
| Polysialic acid restrains inflammatory monocyte maturation. | Passos I et al. | β | 2025 | β |
| Positive Selection Shapes Breast Cancer Tumor Suppressor Genes: Unveiling Insights into BRCA1, BRCA2, and MDC1 Stability. | Fadel YM et al. | β | 2025 | β |
| Potential Adaptive Introgression From Dogs in Iberian Grey Wolves (Canis lupus). | Sarabia C et al. | β | 2025 | β |
| PPDPF is not a key regulator of human pancreas development. | Breunig M et al. | β | 2025 | β |
| Predictive gene expression signatures for Alzheimer's disease using post-mortem brain tissue. | Duche AH et al. | β | 2025 | β |
| Pre-existing epigenetic state and differential NF-ΞΊB activation shape type 2 immune cell responses. | Guichard V et al. | β | 2025 | β |
| Preventing hypocontractility-induced fibroblast expansion alleviates dilated cardiomyopathy. | Bretherton RC et al. | β | 2025 | β |
| Primate retroelement exonization and sexually dimorphic <i>IL13RA1</i> transcription tune type 2 immune responses. | Plowman T et al. | β | 2025 | β |
| Profiling X chromosome genes expression relevant to sex dimorphism in stroke: insights from transcriptomics landscape analysis. | Qin XD et al. | β | 2025 | β |
| Prognosis and treatment response stratification according to loss of proofreading (LOP) <i>POLE</i> variants. | Maddalena G et al. | β | 2025 | β |
| Programs, origins and immunomodulatory functions of myeloid cells in glioma. | Miller TE et al. | β | 2025 | β |
| Propelling sustainable energy: Multi-omics analysis of pennycress FATTY ACID ELONGATION1 knockout for biofuel production. | Rasoul A et al. | β | 2025 | β |
| Prospective Investigation Unravels Plasma Proteomic Links to Dementia. | Li J et al. | β | 2025 | β |
| Prospects for the Protective Mechanisms and Compounds of Bufei Huoxue Capsule against COVID-19 Convalescence: Evaluation of Integrating UHPLC-HRMS Analysis and Network Pharmacology Strategy. | Xie YZ et al. | β | 2025 | β |
| Proteasomes accumulate in the plant apoplast where they participate in microbe-associated molecular pattern (MAMP)-triggered pathogen defense. | Karimi HZ et al. | β | 2025 | β |
| Protective Effects of Resveratrol Against Perfluorooctanoic Acid-Induced Testicular and Epididymal Toxicity in Adult Rats Exposed During Their Prepubertal Period. | Pavani R et al. | β | 2025 | β |
| Protein-Protein Interactions in Papillary and Nonpapillary Urothelial Carcinoma Architectures: Comparative Study. | Chou C et al. | β | 2025 | β |
| Proteomic analysis reveals distinct cerebrospinal fluid signatures across genetic frontotemporal dementia subtypes. | Sogorb-Esteve A et al. | β | 2025 | β |
| Proteomic and metabolomic insights into oxidative stress response activation in mouse embryos generated by <i>in vitro</i> fertilization. | Lee SH et al. | β | 2025 | β |
| Proteomic Changes Associated With Endogenous FBXW7 Mutations in Moderately Differentiated Endometrial Cancer Cells Include Increased TROP2 and Galectin-3 Levels. | Urick ME et al. | β | 2025 | β |
| Proteomic profiling identifies muscle-invasive bladder cancers with distinct biology and responses to platinum-based chemotherapy. | Contreras-Sanz A et al. | β | 2025 | β |
| Proteomic Signatures of SARS-CoV-2 Susceptibility in Mexican Free-tailed Bats and Their Application to Viral Surveillance. | Becker DJ et al. | β | 2025 | β |
| Proteomic study identifies Aurora-A-mediated regulation of alternative splicing through multiple splicing factors. | Damodaran AP et al. | β | 2025 | β |
| Proximal and Classic Epithelioid Sarcomas are Distinct Molecular Entities Defined by MYC/GATA3 and SOX17/Endothelial Markers, Respectively. | Sigalotti L et al. | β | 2025 | β |
| Proximity-specific ribosome profiling reveals the logic of localized mitochondrial translation. | Luo J et al. | β | 2025 | β |
| Quantitative Proteomics and Molecular Mechanisms of Non-Hodgkin Lymphoma Mice Treated with Incomptine A, Part II. | GarcΓa-HernΓ‘ndez N et al. | β | 2025 | β |
| Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines. | Krawczyk PS et al. | β | 2025 | β |
| Recalibrating differential gene expression by genetic dosage variance prioritizes functionally relevant genes. | Rentzsch P et al. | β | 2025 | β |
| Reduction of NFX1-123 and HPV 16 E6 and E7 Decreased Telomerase and CENP-F in Cervical Cancer Cell Lines. | Chintala S et al. | β | 2025 | β |
| Regional and aging-specific cellular architecture of non-human primate brains. | Wang YM et al. | β | 2025 | β |
| Regulating the cell differentiation trajectory of progenitor cells in adipose tissue fibrosis. | Zhang L et al. | β | 2025 | β |
| Regulation of meristem and hormone function revealed through analysis of directly-regulated SHOOT MERISTEMLESS target genes. | Lechon T et al. | β | 2025 | β |
| Regulatory analysis of root architectural and anatomical adaptation to nitrate and ammonium in <i>Brachypodium distachyon</i>. | Rouina H et al. | β | 2025 | β |
| Requirements for establishment and epigenetic stability of mammalian heterochromatin. | Tatarakis A et al. | β | 2025 | β |
| Resting-State Brain Activity Changes and Their Genetic Correlates in Mild Traumatic Brain Injury. | Wang L et al. | β | 2025 | β |
| RNA-Seq transcriptomic landscape profiling of spontaneously hypertensive rats in youth treated with a ARNI versus ARB. | Ma J et al. | β | 2025 | β |
| RNA Sequencing Revealed Distinct Expression Profiles and Temporal Expression Dynamics in Murine Model of Foreign Body Reaction. | Riew TR et al. | β | 2025 | β |
| Role of clonal inflammatory microglia in histiocytosis-associated neurodegeneration. | Vicario R et al. | β | 2025 | β |
| Role of histone-lysine N-methyltransferase 2D (KMT2D) in MEK-ERK signaling-mediated epigenetic regulation: a phosphoproteomics perspective. | Kammarambath SR et al. | β | 2025 | β |
| Role of Ocrelizumab in modulating gene and microRNA expression in multiple sclerosis. | De Felice B et al. | β | 2025 | β |
| Ropinirole Functions Through a Dopamine Receptor D2-Independent Mechanism to Ameliorate Amyotrophic Lateral Sclerosis Phenotypes in TARDBP-Mutant iPSC-Derived Motor Neurons. | Asano H et al. | β | 2025 | β |
| SC-VAR: a computational tool for interpreting polygenic disease risks using single-cell epigenomic data. | Zhao G et al. | β | 2025 | β |
| Secretory IgA binding to FCRL3 triggers shared inflammatory cytokine secretion by human regulatory T cells and effector T cells. | Kraus Z et al. | β | 2025 | β |
| SEgene identifies links between super enhancers and gene expression across cell types. | Shinkai N et al. | β | 2025 | β |
| SEPAR enables spatial metagene discovery and associated molecular pattern characterization in spatial transcriptomics and multi-omics datasets. | Zhang L et al. | β | 2025 | β |
| Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk. | Choi SH et al. | β | 2025 | β |
| SETD1A regulates psychiatric gene networks involved in genomic stability and synaptic function in rare and sporadic schizophrenia. | Sawada T et al. | β | 2025 | β |
| Severe pathological and transcriptional changes in haematopoietic organs of salmon suffering from salmon gill poxvirus disease. | Benedicenti O et al. | β | 2025 | β |
| Sexually dimorphic gene expression responses of bovine embryos to the maternal microenvironment on day 13 of gestation. | Salilew-Wondim D et al. | β | 2025 | β |
| Shared genetic risk and causal associations between Post-traumatic stress disorder and migraine with antithrombotic agents and other medications. | Bainomugisa CK et al. | β | 2025 | β |
| Silent mutations in coding regions of Hepatitis C virus affect patterns of HCV RNA structures and attenuate viral replication and pathogenesis. | Dabour R et al. | β | 2025 | β |
| Simultaneous cyclin D1 overexpression and p27<sup>kip1</sup> knockdown enable robust MΓΌller glia cell cycle reactivation in uninjured mouse retina. | Wu Z et al. | β | 2025 | β |
| Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes. | Mills M et al. | β | 2025 | β |
| Single-cell and Spatial Transcriptomics Illuminate Bat Immunity and Barrier Tissue Evolution. | Levinger R et al. | β | 2025 | β |
| Single-cell compendium of muscle microenvironment in peripheral artery disease reveals altered endothelial diversity and LYVE1<sup>+</sup> macrophage activation. | Turiel G et al. | β | 2025 | β |
| Single-cell delineation of the microbiota-gut-brain axis: Probiotic intervention in Chd8 haploinsufficient mice. | Ji P et al. | β | 2025 | β |
| Single-cell RNA sequencing defines developmental progression and reproductive transitions of <i>Pneumocystis carinii</i>. | Albee AW et al. | β | 2025 | β |
| Single-cell RNA sequencing of adult primate neocortex reveals the regulatory dynamics of neural plasticity. | Zhang C et al. | β | 2025 | β |
| Single-cell RNA sequencing reveals a B cell-related immunosuppressive landscape and a potential suppressor in hepatocellular carcinoma. | Hou W et al. | β | 2025 | β |
| Single-Cell Transcriptome Patterns of Transposable Elements in Alzheimer's Disease. | McEntee CM et al. | β | 2025 | β |
| Single-cell transcriptomic reconstruction of the human hair cycle: Capturing the temporal dynamics of skin tissue remodeling. | Yokota J et al. | β | 2025 | β |
| Single nuclei transcriptomics reveals cellular diversity in TSC subependymal giant cell astrocytomas. | Holmberg JC et al. | β | 2025 | β |
| Single-nucleotide polymorphism analysis accurately predicts multiple impairments in hippocampal activity and memory performance in a murine model of idiopathic autism. | BarΓ³n-Mendoza I et al. | β | 2025 | β |
| Site- and cell-type-specific miRNA and mRNA genes and networks across the cortex, striatum, and hypothalamus. | Zacharias AM et al. | β | 2025 | β |
| Smoking and alcohol specific alterations in miRNA expression in head and neck squamous cell carcinoma. | Bhat MY et al. | β | 2025 | β |
| Sox8 is essential for vertebrate gastrulation. | Moreira S et al. | β | 2025 | β |
| Space-associated stem cell hallmarks of aging and resilience in astronauts. | Pham J et al. | β | 2025 | β |
| SpaICL: image-guided curriculum strategy-based graph contrastive learning for spatial transcriptomics clustering. | Zhao J et al. | β | 2025 | β |
| SpaMask: Dual masking graph autoencoder with contrastive learning for spatial transcriptomics. | Min W et al. | β | 2025 | β |
| Spatial and functional profiles distinguish target sets of Parkinson's disease and antipsychotic drugs with different clinical effects. | Karunakaran KB et al. | β | 2025 | β |
| Spatial and single cell mapping of castleman disease reveals key stromal cell types and cytokine pathways. | Smith D et al. | β | 2025 | β |
| Spatial and Single-Cell Transcriptomics Unraveled Spatial Evolution of Papillary Thyroid Cancer. | Zheng G et al. | β | 2025 | β |
| Spatial Transcriptome and Single Nucleus Transcriptome Sequencing Reveals Tetrahydroxy Stilbene Glucoside Promotes Ovarian Organoids Development Through the Vegfa-Ephb2 Pair. | Mu C et al. | β | 2025 | β |
| Spatial Transcriptomic Analysis of Surgical Resection Specimens of Primary Head and Neck Squamous Cell Carcinoma Treated with Afatinib in a Window-of-Opportunity Study (EORTC90111-24111). | Beyaert S et al. | β | 2025 | β |
| Spatiotemporal profile of an optimal host response to virus infection in the primate central nervous system. | Maximova OA et al. | β | 2025 | β |
| Spectral divergence prioritizes key classes, genes, and pathways shared between substance use disorders and cardiovascular disease. | Castaneda E et al. | β | 2025 | β |
| Sperm derived H2AK119ub1 is required for embryonic development in Xenopus laevis. | Francois-Campion V et al. | β | 2025 | β |
| Sporophyte-directed gametogenesis in Arabidopsis. | Sivakumar P et al. | β | 2025 | β |
| Stage-specific transcriptomic analysis reveals insights into the development, reproduction and biological function of allergens in the European house dust mite Dermatophagoides pteronyssinus. | Vidal-Quist JC et al. | β | 2025 | β |
| Stage-specific transcriptomic and DNA methylation responses to triploidy in European sea bass embryos and larvae. | Beato S et al. | β | 2025 | β |
| Stromal-Like Cells and Retinal Pigment Epithelium Modulate Choroidal Sprouting Through Galectin-1-Dependent and Independent Pathways. | Ridano ME et al. | β | 2025 | β |
| Strong Signatures of Selection on Candidate Genes Underlying Core Speciation Mechanisms in Desert Tortoises. | Baty SM et al. | β | 2025 | β |
| Subcellular proteomics and iPSC modeling uncover reversible mechanisms of axonal pathology in Alzheimer's disease. | Cai Y et al. | β | 2025 | β |
| Surviving the Heat: Genetic Diversity and Adaptation in Sudanese Butana Cattle. | Neumann GB et al. | β | 2025 | β |
| Synaptic signatures and disease vulnerabilities of layer 5 pyramidal neurons. | Marcassa G et al. | β | 2025 | β |
| Synovial Gene expression after Hemarthrosis differs between FVIII-deficient mice treated with recombinant FVIII or FVIII-Fc Fusion Protein. | Chumappumkal Joseph B et al. | β | 2025 | β |
| Systematic Characterization of LUHMES Cell-Based Parkinson's Disease Models Reveals Potential Novel Drug Targets. | YiΔit EN et al. | β | 2025 | β |
| Systematic study of hybrid triplex topology and stability suggests a general triplex-mediated regulatory mechanism. | Genna V et al. | β | 2025 | β |
| Systems genetics reveals the influence of expression QTLs in mouse embryonic stem cells on transcriptional variation later in differentiated neural progenitor cells. | Aydin S et al. | β | 2025 | β |
| Targeting angiogenesis in endometriosis: a systematic review and network meta-analysis of VEGF-directed pharmacotherapies. | Hammond O et al. | β | 2025 | β |
| Targeting CB2 receptor with a novel antagonist reverses cognitive decline, neurodegeneration and pyroptosis in a TAU-dependent frontotemporal dementia mouse model. | Silva-Llanes I et al. | β | 2025 | β |
| Targeting serine metabolism vulnerability in omipalisib-resistant acute myeloid leukemia with phosphoglycerate dehydrogenase inhibitors. | Tseng CY et al. | β | 2025 | β |
| Targeting SUMOylation in ovarian cancer: Sensitivity, resistance, and the role of MYC. | Littler S et al. | β | 2025 | β |
| Tau uptake by human neurons depends on receptor LRP1 and kinase LRRK2. | Evans LD et al. | β | 2025 | β |
| TCR repertoire of human cytotoxic CD4 T cells responding to betaherpesviruses HHV-6B and HCMV. | Becerra-Artiles A et al. | β | 2025 | β |
| Temporal Expression Analysis to Unravel Gene Regulatory Dynamics by microRNAs. | Maji RK et al. | β | 2025 | β |
| Temporal transcriptome profiling in the response to Salmonella enterica serovar enteritidis infection in chicken cecum. | Peng Y et al. | β | 2025 | β |
| Tet Methylcytosine Dioxygenase 2 (TET2) Mutation Drives a Global Hypermethylation Signature in Patients With Pulmonary Arterial Hypertension (PAH): Correlation With Altered Gene Expression Relevant to a Common T Cell Phenotype. | Hindmarch CCT et al. | β | 2025 | β |
| Tetracycline has no long-term effects on gut physiology and microbiome of the new world screwworm, Cochliomyia hominivorax, which has positive implications for transgenic male-only rearing systems. | Arp AP et al. | β | 2025 | β |
| The Atlantic salmon gill transcriptional response to natural infection with HPR0-ISAV (Isavirus salaris) in three Norwegian smolt farms. | Benedicenti O et al. | β | 2025 | β |
| The Atlas of Protein-Protein Interactions in Cancer (APPIC)-a webtool to visualize and analyze cancer subtypes. | Ahn B et al. | β | 2025 | β |
| The BBX7/8-CCA1/LHY transcription factor cascade promotes shade avoidance by activating PIF4. | Bian Y et al. | β | 2025 | β |
| The crucial role of mitochondrial/chloroplast-related genes in viral genome replication and host defense: integrative systems biology analysis in plant-virus interaction. | Shahriari AG et al. | β | 2025 | β |
| The Dynamic Landscape of 3'-UTR Alternative Polyadenylation Across Mouse Fetal Development and Anatomy. | Wang Q et al. | β | 2025 | β |
| The effects of space radiation on the transcriptome of heart right ventricle tissue. | Zakharyan R et al. | β | 2025 | β |
| The Genetic Architecture of the Human Corpus Callosum and its Subregions. | Bhatt RR et al. | β | 2025 | β |
| The Germline and Somatic Origins of Prostate Cancer Heterogeneity. | Yamaguchi TN et al. | β | 2025 | β |
| The HPV101 E7 protein shares host cellular targets and biological activities with high-risk HPV16 E7. | Gelbard MK et al. | β | 2025 | β |
| The Interplay of Ontogeny and Phylogeny at the Transcriptome Level of the Tetrapod Heart. | Cordero GA et al. | β | 2025 | β |
| The lncRNA LOC100257036 and vvimiR156 modulate gibberellin signaling through AGAMOUS during cluster formation in Sistan Yaghooti grape. | Sahraei S et al. | β | 2025 | β |
| The <i>Toxoplasma gondii</i> homolog of ATPase inhibitory factor 1 is critical for mitochondrial cristae maintenance and stress response. | Usey MM et al. | β | 2025 | β |
| The mechanotransducer Piezo1 coordinates metabolism and inflammation to promote skin growth. | Xue Y et al. | β | 2025 | β |
| The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeutic targets. | Knol JC et al. | β | 2025 | β |
| The Proteomic Landscape of the Coronary Accessible Heart Cell Surfaceome. | Inocencio I et al. | β | 2025 | β |
| Therapeutic Effects of Topical Traditional Chinese Medicine on Upper Extremity Fractures. | Lin WY et al. | β | 2025 | β |
| Therapeutic role of Crateva religiosa in diabetic nephropathy: Insights into key signaling pathways. | Ali M et al. | β | 2025 | β |
| The role of DNA content in shaping chromatin architecture and gene expression. | BarragΓ‘n-Rosillo AC et al. | β | 2025 | β |
| The Transcriptome Trajectory Reveals Sex- and Age-Dependent Changes in the Mouse Adrenal Gland. | Wang H et al. | β | 2025 | β |
| The transcriptomic landscape of monosomy X (45,X) during early human fetal and placental development. | Suntharalingham JP et al. | β | 2025 | β |
| The transcriptomic signature of DEPDC5 KO induced mTOR hyperactivation in human neurons and its response to rapamycin treatment. | Jones MSO et al. | β | 2025 | β |
| TNFRSF1A and NCF1 May Act as Hub Genes in Mastitis. | Soleiman Ekhtiyari M et al. | β | 2025 | β |
| TOP2A inhibition and its cellular effects related to cell cycle checkpoint adaptation pathway. | Arroyo M et al. | β | 2025 | β |
| Transcriptional Consequences of MeCP2 Knockdown and Overexpression in Mouse Primary Cortical Neurons. | Rezapour M et al. | β | 2025 | β |
| Transcriptional profiling of <i>Chlamydia trachomatis</i> and its host in an <i>ex vivo</i> endocervical primary cell culture system using dual RNA sequencing. | Olagoke O et al. | β | 2025 | β |
| Transcriptional signatures of gray matter volume changes in mild traumatic brain injury. | Wang L et al. | β | 2025 | β |
| Transcription fidelity and control of alternative splicing contribute to heat stress survival in Arabidopsis. | Szaker HM et al. | β | 2025 | β |
| Transcriptome alterations related to heat stress responses of wild and cultivated barley. | Bahrami F et al. | β | 2025 | β |
| Transcriptome analyses of mRNA and circular RNA reveal dietary supplementation with freeze-dried Lactiplantibacillus plantarum primes immune memory of Whiteleg shrimp (Penaeus vannamei) against pathogens. | Guzman JPMD et al. | β | 2025 | β |
| Transcriptome Analysis of HNSCC by Aggregatibacter actinomycetemcomitans Extracellular Vesicles. | Ha JY et al. | β | 2025 | β |
| Transcriptome Analysis Suggests PKD3 Regulates Proliferative Glucose Metabolism, Calcium Homeostasis and Microtubule Dynamics After MEF Spontaneous Immortalization. | Loaiza-Moss J et al. | β | 2025 | β |
| Transcriptome dynamics in the Arabidopsis male germline during pollen-pistil interactions. | Misra CS et al. | β | 2025 | β |
| Transcriptome profiling implicates ANNEXIN1 in light sensitivity and hormonal balance maintenance in Arabidopsisthaliana. | Rachowka J et al. | β | 2025 | β |
| Transcriptome profiling in an in vitro peripheral blood mononuclear cell - Mycobacterium tuberculosis infection model reveals breed-specific immune gene signatures potentially associated with tuberculosis susceptibility in cattle. | Kumar R et al. | β | 2025 | β |
| Transcriptomic analyses of peripheral blood mononuclear cells reveal age-specific basal and acute exercise responsiveness differences in humans. | Ruple BA et al. | β | 2025 | β |
| Transcriptomic analysis and epigenetic regulators in human oocytes at different stages of oocyte meiotic maturation. | CaniΓ§ais C et al. | β | 2025 | β |
| Transcriptomic Analysis of Peripheral Blood Mononuclear Cells During <i>Ostertagia ostertagi</i> Infection in Cattle Highlights a Generalized Host Immune Reaction. | Fleming DS et al. | β | 2025 | β |
| Transcriptomic Analysis of the Rainbow Trout Response to Single and Co-Infections with <i>Myxobolus cerebralis</i> and <i>Tetracapsuloides bryosalmonae</i> at Sites of Parasite Entry. | Akram N et al. | β | 2025 | β |
| Transcriptomic dose-response by UVC and heavy ion radiation reveal pathways to immune impairment. | Tian M et al. | β | 2025 | β |
| Transcriptomic evidence of cytokine storm and sepsis in little brown bats exposed to white-nose syndrome. | Kwait RE et al. | β | 2025 | β |
| Transcriptomic insights into <i>Mycobacterium orygis</i> infection-associated pulmonary granulomas reveal multicellular immune networks and tuberculosis biomarkers in cattle. | Kumar R et al. | β | 2025 | β |
| Transcriptomic Profile of Perineural Invasion in Prostate Cancer Identifies Prognostic Gene Signatures. | Aktan C et al. | β | 2025 | β |
| Transcriptomic profiling of cardiac development in Bama Xiang pigs across key developmental stages. | Wang SN et al. | β | 2025 | β |
| Transcriptomic profiling of murine GnRH neurons reveals developmental trajectories linked to human reproduction and infertility. | Zouaghi Y et al. | β | 2025 | β |
| Transcriptomics profiling of Parkinson's disease progression subtypes reveals distinctive patterns of gene expression. | Fabrizio C et al. | β | 2025 | β |
| Translation regulation promotes stress adaptation in the human fungal pathogen Candida glabrata. | Rana A et al. | β | 2025 | β |
| Transposable element expression is associated with sex chromosome number in humans. | Teoli J et al. | β | 2025 | β |
| TRB proteins in moss reveal their evolutionarily conserved roles in plant development and telomere maintenance. | KusovΓ‘ A et al. | β | 2025 | β |
| Treatment-Induced Gene Expression Changes in Metastatic Renal Cell Carcinoma: Insights from a Syngeneic Mouse Model. | Okabe K et al. | β | 2025 | β |
| Treg activation during allograft tolerance induction requires mitochondrion-induced TGF-Ξ²1 in type 1 conventional dendritic cells. | Schroth SL et al. | β | 2025 | β |
| Tryptophan-induced transcriptomic changes in the European Seabass are highly dependent on neuroendocrine-immune conditions. | Peixoto D et al. | β | 2025 | β |
| Tumor microenvironments with an active type I IFN response are sensitive to inhibitors of heme degradation. | Sosnowska D et al. | β | 2025 | β |
| Type 2 Innate Lymphoid Cell (Ilc2)-Deficient Mice Are Transcriptionally Constrained During <i>Nippostrongylus brasiliensis</i> Infection. | Fleming DS et al. | β | 2025 | β |
| Ultradeep N-glycoproteome atlas of mouse reveals spatiotemporal signatures of brain aging and neurodegenerative diseases. | Fang P et al. | β | 2025 | β |
| Unveiling functional module associated with fungal disease stress in barley (<i>Hordeum vulgare</i>). | Panahi B et al. | β | 2025 | β |
| Use of brain MRI and gene expression atlases to reconstruct the pathophysiology of autoimmune neurological disorders: The proof-of-concept of NMOSD. | Cacciaguerra L et al. | β | 2025 | β |
| Using a novel panel of drug-resistant triple-negative breast cancer cell lines to identify candidate therapeutic targets and biomarkers. | Grimsley HE et al. | β | 2025 | β |
| Using novel approaches to conjugate peptides of Macrotermes bellicosus and Curcuma longa for targeted intervention of irritable bowl diseases caused by tumor necrosis factor superfamily member 15 (TNFSF15). | Naveed M et al. | β | 2025 | β |
| Using pseudotime derivative on single-cell RNA sequencing data to identify genes undergoing cell cycle regulation. | Lefol Y et al. | β | 2025 | β |
| Voluntary Exercise Attenuates Tumor Growth in a Preclinical Model of Castration-Resistant Prostate Cancer. | Berger N et al. | β | 2025 | β |
| Whole-exome sequencing study of opioid dependence offers novel insights into the contributions of exome variants. | Wang L et al. | β | 2025 | β |
| Whole-Genome Insights into the Genetic Basis of Conformation Traits in German Black Pied (DSN) Cattle. | Mandel A et al. | β | 2025 | β |
| Whole-genome resequencing reveals positive selection and introgression signatures and genetic loci associated with early puberty traits in Chinese indigenous pigs. | Cao M et al. | β | 2025 | β |
| Whole transcriptome analysis reveals T cell signaling activation in septic patients with thrombocytopenia. | Chen IC et al. | β | 2025 | β |
| Widespread Genetic Signals of Visual System Adaptation in Deepwater Cichlid Fishes. | Camacho GarcΓa JI et al. | β | 2025 | β |
| ZHX3 interacts with CEBPB to repress hepatic gluconeogenic gene expression and uric acid secretion. | Tan WX et al. | β | 2025 | β |
| ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF. | Magnitov MD et al. | β | 2025 | β |
| 3D-printed airway model as a platform for SARS-CoV-2 infection and antiviral drug testing. | Lee Y et al. | β | 2024 | β |
| Aberrant CHCHD2-associatedΒ mitochondriopathy in Kii ALS/PDC astrocytes. | Leventoux N et al. | β | 2024 | β |
| Accelerated evolution in the human lineage led to gain and loss of transcriptional enhancers in the <i>RBFOX1</i> locus. | Berasain L et al. | β | 2024 | β |
| A combination of plant-based compounds and extracts acts nematicidal and induces resistance against <i>Meloidogyne incognita</i> in tomato. | Degroote E et al. | β | 2024 | β |
| A comprehensive landscape analysis of autophagy in cancer development and drug resistance. | Li Y et al. | β | 2024 | β |
| Acquisition of epithelial plasticity in human chronic liver disease. | Gribben C et al. | β | 2024 | β |
| Acyl-CoA binding protein for the experimental treatment of anorexia. | Chen H et al. | β | 2024 | β |
| A deep learning model for prediction of autism status using whole-exome sequencing data. | Wu Q et al. | β | 2024 | β |
| Adipocytes reprogram the proteome of breast cancer cells in organotypic three-dimensional cell cultures. | Tovar-HernΓ‘ndez K et al. | β | 2024 | β |
| Age-associated imbalance in immune cell regeneration varies across individuals and arises from a distinct subset of stem cells. | Nogalska A et al. | β | 2024 | β |
| Age-Related ECM Stiffness Mediates TRAIL Activation in Muscle Stem Cell Differentiation. | Alakhdar AA et al. | β | 2024 | β |
| Akt and AMPK activators rescue hyperexcitability in neurons from patients with bipolar disorder. | Khayachi A et al. | β | 2024 | β |
| A large-scale proteomics resource of circulating extracellular vesicles for biomarker discovery in pancreatic cancer. | Bockorny B et al. | β | 2024 | β |
| ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma. | Lu Y et al. | β | 2024 | β |
| Altered centriolar cohesion by CEP250 and appendages impact outcome of patients with pancreatic cancer. | Giordano G et al. | β | 2024 | β |
| Altered hepatic metabolic landscape and insulin sensitivity in response to pulmonary tuberculosis. | Das MK et al. | β | 2024 | β |
| Alternative splicing regulation in plants by SP7-like effectors from symbiotic arbuscular mycorrhizal fungi. | Betz R et al. | β | 2024 | β |
| Alzheimer's disease associated isoforms of human CD33 distinctively modulate microglial cell responses in 5XFAD mice. | Eskandari-Sedighi G et al. | β | 2024 | β |
| Alzheimer's disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non-demented individuals. | Lorenzini L et al. | β | 2024 | β |
| Alzheimer's disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity. | PaveΕ‘koviΔ M et al. | β | 2024 | β |
| A male mouse model for metabolic dysfunction-associated steatotic liver disease and hepatocellular carcinoma. | Jeong BK et al. | β | 2024 | β |
| Aminoglycoside heteroresistance in <i>Enterobacter cloacae</i> is driven by the cell envelope stress response. | Choi AJ et al. | β | 2024 | β |
| A miR-383-5p Signaling Hub Coordinates the Axon Regeneration Response to Inflammation. | Hintermayer MA et al. | β | 2024 | β |
| A Multi-Omics Study of Epigenetic Changes in Type II Alveolar Cells of A/J Mice Exposed to Environmental Tobacco Smoke. | Han Q et al. | β | 2024 | β |
| Amyloid Ξ² accelerates age-related proteome-wide protein insolubility. | Anderton E et al. | β | 2024 | β |
| An activity-specificity trade-off encoded in human transcription factors. | Naderi J et al. | β | 2024 | β |
| An AI Agent for Fully Automated Multi-Omic Analyses. | Zhou J et al. | β | 2024 | β |
| Analysis of Active Components and Transcriptome of <i>Freesia refracta</i> Callus Extract and Its Effects against Oxidative Stress and Wrinkles in Skin. | Kim E et al. | β | 2024 | β |
| A new cell culture resource for investigations of reptilian gene function. | Samudra SP et al. | β | 2024 | β |
| An InDel variant in the promoter of the NAC transcription factor MdNAC18.1 plays a major role in apple fruit ripening. | Yue Q et al. | β | 2024 | β |
| Anti-MΓΌllerian hormone type II receptor protein expression in non-small cell lung cancer and the effect of AMH/AMHR2 signaling on cancer cell proliferation. | Koinuma Y et al. | β | 2024 | β |
| A small intestinal bile acid modulates the gut microbiome to improve host metabolic phenotypes following bariatric surgery. | Chen Y et al. | β | 2024 | β |
| Associations between accelerometer-measured circadian rest-activity rhythm, brain structural and genetic mechanisms, and dementia. | Liu Y et al. | β | 2024 | β |
| A temporal cortex cell atlas highlights gene expression dynamics during human brain maturation. | Steyn C et al. | β | 2024 | β |
| A time series transcriptome profiling of host cell responses to Newcastle disease virus infection. | Nayak BN et al. | β | 2024 | β |
| A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity-dependent synaptic and microglial transcriptomic changes in a late-stage Alzheimer's mouse model. | Latif-Hernandez A et al. | β | 2024 | β |
| At the crossroads: strigolactones mediate changes in cytokinin synthesis and signalling in response to nitrogen limitation. | Sigalas PP et al. | β | 2024 | β |
| Atypical cellular responses mediated by intracellular constitutive active TrkB (NTRK2) kinase domains and a solely intracellular NTRK2-fusion oncogene. | Gupta R et al. | β | 2024 | β |
| AutoCancer as an automated multimodal framework for early cancer detection. | Liu L et al. | β | 2024 | β |
| A validated heart-specific model for splice-disrupting variants in childhood heart disease. | Lesurf R et al. | β | 2024 | β |
| AZGP1 deficiency promotes angiogenesis in prostate cancer. | Wen RM et al. | β | 2024 | β |
| BCL6 is a context-dependent mediator of the glioblastoma response to irradiation therapy. | Tribe AKW et al. | β | 2024 | β |
| BCR, not TCR, repertoire diversity is associated with favorable COVID-19 prognosis. | Paran FJ et al. | β | 2024 | β |
| Biallelic PI4KA Mutations Disrupt B-Cell Metabolism and Cause B-Cell Lymphopenia and Hypogammaglobulinemia. | Saettini F et al. | β | 2024 | β |
| Bioinformatic characterization of ENPEP, the gene encoding a potential cofactor for SARS-CoV-2 infection. | Arppo A et al. | β | 2024 | β |
| BLESS: bagged logistic regression for biomarker identification. | Gardiner K et al. | β | 2024 | β |
| Bone marrow stromal cells induce chromatin remodeling in multiple myeloma cells leading to transcriptional changes. | Binder M et al. | β | 2024 | β |
| Canine hyper-sociability structural variants associated with altered three-dimensional chromatin state. | Tandon D et al. | β | 2024 | β |
| Cannabidiol ameliorates mitochondrial disease via PPARΞ³ activation in preclinical models. | Puighermanal E et al. | β | 2024 | β |
| Cardiac Development Long Non-Coding RNA (<i>CARDEL</i>) Is Activated during Human Heart Development and Contributes to Cardiac Specification and Homeostasis. | Pereira IT et al. | β | 2024 | β |
| Cerebral hypoperfusion exacerbates traumatic brain injury in male but not female mice. | Whitehead BJ et al. | β | 2024 | β |
| Cerebral hypoperfusion exacerbates vascular dysfunction after traumatic brain injury. | Whitehead B et al. | β | 2024 | β |
| Characterization of Circulating Protein Profiles in Individuals with Prader-Willi Syndrome and Individuals with Non-Syndromic Obesity. | Pascut D et al. | β | 2024 | β |
| Characterization of the Regulatory Network under Waterlogging Stress in Soybean Roots via Transcriptome Analysis. | Yoo YH et al. | β | 2024 | β |
| Chronic Activation of Tubulin Tyrosination Improves Heart Function. | Pietsch N et al. | β | 2024 | β |
| Circadian control of histone turnover during cardiac development and growth. | Arrieta A et al. | β | 2024 | β |
| Circadian regulation of macromolecular complex turnover and proteome renewal. | Seinkmane E et al. | β | 2024 | β |
| Circulating Neutrophil Profiles Undergo a Dynamic Shift during Metabolic Dysfunction-Associated Steatohepatitis (MASH) Progression. | Maretti-Mira AC et al. | β | 2024 | β |
| Classification of distinct tendinopathy subtypes for precision therapeutics. | Tang C et al. | β | 2024 | β |
| COL10A1 expression distinguishes a subset of cancer-associated fibroblasts present in the stroma of high-risk basal cell carcinoma. | Esposito M et al. | β | 2024 | β |
| Colony-stimulating factor 2 (CSF2) as a gut microbiome dependent immune factor that alters molecular and behavioral responses to cocaine in male mice. | Lucerne KE et al. | β | 2024 | β |
| Combined inhibition of EZH2 and CDK4/6 perturbs endoplasmic reticulum-mitochondrial homeostasis and increases antitumor activity against glioblastoma. | Freitag T et al. | β | 2024 | β |
| Commentary: Evaluation of the causal effects of immune cells on ischemic stroke: a Mendelian randomization study. | Zhu X et al. | β | 2024 | β |
| Comparative Analysis of Shapley Values Enhances Transcriptomics Insights across Some Common Uterine Pathologies. | Castro-MartΓnez JA et al. | β | 2024 | β |
| Comparative transcriptome analysis reveals a serotype-specific immune response in Nile tilapia (<i>Oreochromis niloticus</i>) infected with <i>Streptococcus agalactiae</i>. | Appel RJC et al. | β | 2024 | β |
| Comparative transcriptome reprogramming in oak galls containing asexual or sexual generations of gall wasps. | Bellows E et al. | β | 2024 | β |
| Comparative ultrastructural and transcriptomic profile analysis of skin tissues from indigenous, improved meat, and dairy goat breeds. | Hou X et al. | β | 2024 | β |
| Comprehensive identification of genomic and environmental determinants of phenotypic plasticity in maize. | Tibbs-Cortes LE et al. | β | 2024 | β |
| Controlled human exposures to diesel exhaust or particle-depleted diesel exhaust with allergen modulates transcriptomic responses in the lung. | Li S et al. | β | 2024 | β |
| CTNND2 moderates the pace of synaptic maturation and links human evolution to synaptic neoteny. | Assendorp N et al. | β | 2024 | β |
| CXCR4 signaling determines the fate of hematopoietic multipotent progenitors by stimulating mTOR activity and mitochondrial metabolism. | Rondeau V et al. | β | 2024 | β |
| Cytoadhesion of Plasmodium falciparum-Infected Red Blood Cells Changes the Expression of Cytokine-, Histone- and Antiviral Protein-Encoding Genes in Brain Endothelial Cells. | Allweier J et al. | β | 2024 | β |
| DAVID Ortholog: an integrative tool to enhance functional analysis through orthologs. | Sherman BT et al. | β | 2024 | β |
| Deciphering novel TCF4-driven mechanisms underlying a common triplet repeat expansion-mediated disease. | Bhattacharyya N et al. | β | 2024 | β |
| Deciphering proteins in Alzheimer's disease: A new Mendelian randomization method integrated with AlphaFold3 for 3D structure prediction. | Yao M et al. | β | 2024 | β |
| Deciphering the genetic code of neuronal type connectivity through bilinear modeling. | Qiao M | β | 2024 | β |
| Deciphering the multi-scale mechanism of herbal phytoconstituents in targeting breast cancer: a computational pharmacological perspective. | Saini H et al. | β | 2024 | β |
| Deciphering the TET3 interactome in primary thymic developing TΒ cells. | Theofilatos D et al. | β | 2024 | β |
| Deconvolution of cell-type-associated markers predictive of response to neoadjuvant radiotherapy. | Zhu M et al. | β | 2024 | β |
| DeepGSEA: explainable deep gene set enrichment analysis for single-cell transcriptomic data. | Xiong G et al. | β | 2024 | β |
| DeepKINET: a deep generative model for estimating single-cell RNA splicing and degradation rates. | Mizukoshi C et al. | β | 2024 | β |
| Defective thyroid hormone transport to the brain leads to astroglial alterations. | GuillΓ©n-Yunta M et al. | β | 2024 | β |
| DELE1 maintains muscle proteostasis to promote growth and survival in mitochondrial myopathy. | Lin HP et al. | β | 2024 | β |
| Development and application of a 1K functional liquid chip for lactation performance in Bactrian camels. | Guo L et al. | β | 2024 | β |
| Development of a Polygenic Risk Score for Metabolic Dysfunction-Associated Steatotic Liver Disease Prediction in UK Biobank. | Giardoglou P et al. | β | 2024 | β |
| Development of hepatocellular carcinoma organoid model recapitulating HIF-1A metabolic signature. | Khedr MA et al. | β | 2024 | β |
| Direct RNA sequencing of astronaut blood reveals spaceflight-associated m6A increases and hematopoietic transcriptional responses. | Grigorev K et al. | β | 2024 | β |
| Discovery of differentially expressed proteins for CAR-T therapy of ovarian cancers with a bioinformatics analysis. | Anurogo D et al. | β | 2024 | β |
| Disruption of metazoan gene regulatory networks in cancer alters the balance of co-expression between genes of unicellular and multicellular origins. | Trigos AS et al. | β | 2024 | β |
| Disruptions in reproductive health, sex hormonal profiles, and hypothalamic hormone receptors content in females of the C58/J mouse model of autism. | BarΓ³n-Mendoza I et al. | β | 2024 | β |
| Dissecting the genetic basis of resistance to Soil-borne cereal mosaic virus (SBCMV)Β in durum wheat by bi-parental mapping and GWAS. | Bruschi M et al. | β | 2024 | β |
| Dissecting the invasion history of Spotted-Wing Drosophila (Drosophila suzukii) in Portugal using genomic data. | Sario S et al. | β | 2024 | β |
| Dissecting the shared genetic architecture between Alzheimer's disease and frailty: a cross-trait meta-analyses of genome-wide association studies. | Enduru N et al. | β | 2024 | β |
| Distinct functional and molecular profiles between physiological and pathological atrial enlargement offer potential new therapeutic opportunities for atrial fibrillation. | Chen YC et al. | β | 2024 | β |
| Distinct network patterns emerge from Cartesian and XOR epistasis models: a comparative network science analysis. | Sha Z et al. | β | 2024 | β |
| Distinct regional vulnerability to AΞ² and iron accumulation in post mortem AD brains. | Yao J et al. | β | 2024 | β |
| Disturbance of Immune Microenvironment in Androgenetic Alopecia through Spatial Transcriptomics. | Charoensuksira S et al. | β | 2024 | β |
| Diverse PFAS produce unique transcriptomic changes linked to developmental toxicity in zebrafish. | Rericha Y et al. | β | 2024 | β |
| DNA methylation analysis reveals local changes in resistant and susceptible soybean lines in response to Phytophthora sansomeana. | DiBiase CN et al. | β | 2024 | β |
| DNMT3B splicing dysregulation mediated by SMCHD1 loss contributes to DUX4 overexpression and FSHD pathogenesis. | Engal E et al. | β | 2024 | β |
| Draft Genome of Akame (Lates Japonicus) Reveals Possible Genetic Mechanisms for Long-Term Persistence and Adaptive Evolution with Low Genetic Diversity. | Hashiguchi Y et al. | β | 2024 | β |
| Drug resistant pancreatic cancer cells exhibit altered biophysical interactions with stromal fibroblasts in imaging studies of 3D co-culture models. | Struth E et al. | β | 2024 | β |
| Drugst.OneΒ -Β a plug-and-play solution for online systems medicine and network-based drug repurposing. | Maier A et al. | β | 2024 | β |
| Dual targeting of histone deacetylases and MYC as potential treatment strategy for H3-K27M pediatric gliomas. | Algranati D et al. | β | 2024 | β |
| Dynamic Hippo pathway activity underlies mesenchymal differentiation during lung alveolar morphogenesis. | Chaudhry FN et al. | β | 2024 | β |
| Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency. | Wu J et al. | β | 2024 | β |
| Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis. | Takaoka M et al. | β | 2024 | β |
| Effects of antibiotic growth promoter and its natural alternative on poultry cecum ecosystem: an integrated analysis of gut microbiota and host expression. | Peng C et al. | β | 2024 | β |
| Effects of microgravity on human iPSC-derived neural organoids on the International Space Station. | Marotta D et al. | β | 2024 | β |
| Effects of nonsynonymous single nucleotide polymorphisms of the <i>KIAA1217</i>, <i>SNTA1</i> and <i>LTBP1</i> genes on the growth traits of Ujumqin sheep. | Liu Z et al. | β | 2024 | β |
| Elevated expression of Aurora-A/AURKA in breast cancer associates with younger age and aggressive features. | Ingebriktsen LM et al. | β | 2024 | β |
| Elongation factor 1A1 inhibition elicits changes in lipid droplet size, the bulk transcriptome, and cell type-associated gene expression in MASLD mouse liver. | Wilson RB et al. | β | 2024 | β |
| Elucidating the role of PPARG inhibition in enhancing MERS virus immune response: A network pharmacology and computational drug discovery. | Hassan AM et al. | β | 2024 | β |
| Endogenous antigens shape the transcriptome and TCR repertoire in an autoimmune arthritis model. | McCarthy EE et al. | β | 2024 | β |
| Endogenous ZAP is associated with altered Zika virus infection phenotype. | Le NPK et al. | β | 2024 | β |
| Endometrial Proliferative Phase-Centered View of Transcriptome Dynamics across the Menstrual Cycle. | Apostolov A et al. | β | 2024 | β |
| Engineering Toxoplasma gondii secretion systems for intracellular delivery of multiple large therapeutic proteins to neurons. | Bracha S et al. | β | 2024 | β |
| Enhancing Transcriptomic Insights into Neurological Disorders Through the Comparative Analysis of Shapley Values. | Castro-MartΓnez JA et al. | β | 2024 | β |
| Ensemble Learning for Higher Diagnostic Precision in Schizophrenia Using Peripheral Blood Gene Expression Profile. | Wagh VV et al. | β | 2024 | β |
| Enzymatic Metabolic Switches of Astrocyte Response to Lipotoxicity as Potential Therapeutic Targets for Nervous System Diseases. | Angarita-RodrΓguez A et al. | β | 2024 | β |
| Epigenetic inheritance of diet-induced and sperm-borne mitochondrial RNAs. | Tomar A et al. | β | 2024 | β |
| Equine herpesvirus type 1 (EHV-1) replication at the upper respiratory entry site is inhibited by neutralizing EHV-1-specific IgG1 and IgG4/7 mucosal antibodies. | Eady NA et al. | β | 2024 | β |
| ERK synchronizes embryonic cleavages in Drosophila. | Yang L et al. | β | 2024 | β |
| ETV4 is a mechanical transducer linking cell crowding dynamics to lineage specification. | Yang S et al. | β | 2024 | β |
| Exercise rejuvenates microglia and reverses T cell accumulation in the aged female mouse brain. | Chauquet S et al. | β | 2024 | β |
| Experimental evolution of multicellularity via cuboidal cell packing in fission yeast. | Pineau RM et al. | β | 2024 | β |
| Exploration of Genome-Wide Recombination Rate Variation Patterns at Different Scales in Pigs. | Chen Z et al. | β | 2024 | β |
| Exploring causal effects of sarcopenia on risk and progression of Parkinson disease by Mendelian randomization. | Wang T et al. | β | 2024 | β |
| Exploring novel natural compound-based therapies for Duchenne muscular dystrophy management: insights from network pharmacology, QSAR modeling, molecular dynamics, and free energy calculations. | Saeed M et al. | β | 2024 | β |
| Exploring the molecular underpinnings of macrosomia in gestational diabetes mellitus: The role of EGFR signaling and placental syncytiotrophoblast. | Xu P et al. | β | 2024 | β |
| Exposure to elevated glucocorticoid during development primes altered transcriptional responses to acute stress in adulthood. | Choi MK et al. | β | 2024 | β |
| Extracellular vesicles from human breast cancer-resistant cells promote acquired drug resistance and pro-inflammatory macrophage response. | Santos P et al. | β | 2024 | β |
| Fate-mapping and functional dissection reveal perilous influence of type I interferon signaling in mouse brain aging. | Roy ER et al. | β | 2024 | β |
| Fibroblast diversification is an embryonic process dependent on muscle contraction. | Coren L et al. | β | 2024 | β |
| Fitness Screens Map State-Specific Glioblastoma Stem Cell Vulnerabilities. | MacLeod G et al. | β | 2024 | β |
| Forebrain Eml1 depletion reveals early centrosomal dysfunction causing subcortical heterotopia. | Zaidi D et al. | β | 2024 | β |
| Functional annotation and meta-analysis of maize transcriptomes reveal genes involved in biotic and abiotic stress. | Hayford RK et al. | β | 2024 | β |
| Functional regression clustering with multiple functional gene expressions. | Conde S et al. | β | 2024 | β |
| Functional transcriptome analysis revealed upregulation of MAPK-SMAD signalling pathways in chronic heat stress in crossbred cattle. | Dutta G et al. | β | 2024 | β |
| Gastric cancer actionable genomic alterations across diverse populations worldwide and pharmacogenomics strategies based on precision oncology. | EcheverrΓa-GarcΓ©s G et al. | β | 2024 | β |
| Gene Expression Sets and Renal Profiling from the Renal AL Amyloid Involvement and NEOD00 (RAIN) Trial. | Varga C et al. | β | 2024 | β |
| Genes divided according to the relative position of the longest intron show increased representation in different KEGG pathways. | Dvorak P et al. | β | 2024 | β |
| Genetic and genomic analysis of reproduction traits in holstein cattle using SNP chip data and imputed sequence level genotypes. | Schwarz L et al. | β | 2024 | β |
| Genetic and neuro-epigenetic effects of divergent artificial selection for feather pecking behaviour in chickens. | de Haas EN et al. | β | 2024 | β |
| Genetic overlap and Mendelian randomization analysis highlighted the causal relationship between psoriatic disease and migraine. | Tan Y et al. | β | 2024 | β |
| Genetic Variants Linked to Opioid Addiction: A Genome-Wide Association Study. | Panday SK et al. | β | 2024 | β |
| Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy. | Zheng SL et al. | β | 2024 | β |
| Genome-wide association study for seedling heat tolerance under two temperature conditions in bread wheat (Triticum aestivum L.). | Fu C et al. | β | 2024 | β |
| Genome-wide association study of the common retinal disorder epiretinal membrane: Significant risk loci in each of three American populations. | Gelernter J et al. | β | 2024 | β |
| Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience. | Jurgens SJ et al. | β | 2024 | β |
| Genome-Wide CRISPR Screen Identifies an NF2-Adherens Junction Mechanistic Dependency for Cardiac Lineage. | Lee CJM et al. | β | 2024 | β |
| Genome-wide cross-disease analyses highlight causality and shared biological pathways of type 2 diabetes with gastrointestinal disorders. | Adewuyi EO et al. | β | 2024 | β |
| Genome-wide DNA methylation and transcriptomic analysis of liver tissues subjected to early ischemia/reperfusion injury upon human liver transplantation. | Giraudi PJ et al. | β | 2024 | β |
| Genome-Wide Patterns of Homozygosity and Heterozygosity and Candidate Genes in Greek Insular and Mainland Native Goats. | Tsartsianidou V et al. | β | 2024 | β |
| Genome-wide patterns of noncoding and protein-coding sequence variation in the major fungal pathogen Aspergillus fumigatus. | Brown A et al. | β | 2024 | β |
| Genome-wide relaxation of selection and the evolution of the island syndrome in Orkney voles. | Wang X et al. | β | 2024 | β |
| Genome-Wide Scans for Selection Signatures in Ningxia Angus Cattle Reveal Genetic Variants Associated with Economic and Adaptive Traits. | Yin H et al. | β | 2024 | β |
| Genomic and transcriptomic landscape to decipher the genetic basis of hyperpigmentation in Lanping black-boned sheep (Ovis aries). | Chong Y et al. | β | 2024 | β |
| Genomic insights into genetic diversity and seed coat color change in common bean composite populations. | Plestenjak E et al. | β | 2024 | β |
| Genomic signatures of positive selection in Awarik dromedary camels from southwestern of Saudi Arabia. | Almathen F | β | 2024 | β |
| Genopyc: a Python library for investigating the functional effects of genomic variants associated to complex diseases. | Gualdi F et al. | β | 2024 | β |
| Gill ionocyte remodeling mediates blood pH regulation in rockfish (<i>Sebastes diploproa</i>) exposed to environmentally relevant hypercapnia. | Kwan GT et al. | β | 2024 | β |
| Global identification of mammalian host and nested gene pairs reveal tissue-specific transcriptional interplay. | Montibus B et al. | β | 2024 | β |
| Gut microbial genomes with paired isolates from China illustrate probiotic and cardiometabolic effects. | Huang P et al. | β | 2024 | β |
| Hallmarks of cancer in patients with heart failure: data from BIOSTAT-CHF. | van den Berg PF et al. | β | 2024 | β |
| HBS1L deficiency causes retinal dystrophy in a child and in a mouse model associated with defective development of photoreceptor cells. | Luo S et al. | β | 2024 | β |
| HiDDEN: a machine learning method for detection of disease-relevant populations in case-control single-cell transcriptomics data. | Goeva A et al. | β | 2024 | β |
| HIF-1Ξ± limits myocardial infarction by promoting mitophagy in mouse hearts adapted to chronic hypoxia. | Alanova P et al. | β | 2024 | β |
| High concentrations of progesterone inhibit the expression of genes related to steroid metabolism in MA-10 Leydig cells. | Izichkis LS et al. | β | 2024 | β |
| Histone-binding protein RBBP4 is necessary to promote neurogenesis in the developing mouse neocortical progenitors. | Dhanya SK et al. | β | 2024 | β |
| Horizontal gene transfer of the Mer operon is associated with large effects on the transcriptome and increased tolerance to mercury in nitrogen-fixing bacteria. | Bhat A et al. | β | 2024 | β |
| HSF-1 promotes longevity through ubiquilin-1-dependent mitochondrial network remodelling. | Erinjeri AP et al. | β | 2024 | β |
| Human Conjunctival Transcriptome in Acanthamoeba Keratitis: An Exploratory Study. | Seitzman GD et al. | β | 2024 | β |
| Huntingtin is an RNA binding protein and participates in <i>NEAT1</i>-mediated paraspeckles. | Yadav M et al. | β | 2024 | β |
| Identification and Characterization of ATOH7-Regulated Target Genes and Pathways in Human Neuroretinal Development. | Atac D et al. | β | 2024 | β |
| Identification of a DNA methylation signature in whole blood of newborn guinea pigs and human neonates following antenatal betamethasone exposure. | Kim B et al. | β | 2024 | β |
| Identification of a transcription factor network regulating anti-TNF mediated <i>IL10</i> expression in human CD4+ T cells. | Povoleri GAM et al. | β | 2024 | β |
| Identification of Candidate Protein Biomarkers Associated with Domoic Acid Toxicosis in Cerebrospinal Fluid of California Sea Lions (<i>Zalophus californianus</i>). | Ghosh G et al. | β | 2024 | β |
| Identification of novel driver risk genes in CNV loci associated with neurodevelopmental disorders. | Azidane S et al. | β | 2024 | β |
| Identification of PPREs and PPRE associated genes in the human genome: insights into related kinases and disease implications. | Saha P et al. | β | 2024 | β |
| Identification of the RSX interactome in a marsupial shows functional coherence with the Xist interactome during X inactivation. | McIntyre KL et al. | β | 2024 | β |
| Identifying transcriptomic profiles in ovine spleen after repetitive vaccination. | Guisasola-Serrano A et al. | β | 2024 | β |
| Immune horses rapidly increase antileukoproteinase and lack type I interferon secretion during mucosal innate immune responses against equine herpesvirus type 1. | Holmes CM et al. | β | 2024 | β |
| Implementation of multiomic mass spectrometry approaches for the evaluation of human health following environmental exposure. | Ferreira CR et al. | β | 2024 | β |
| Improved breast milk proteome coverage by DIA based LC-MS/MS method. | Viitaharju J et al. | β | 2024 | β |
| Improving iPSC Differentiation Using a Nanodot Platform. | Chiew MY et al. | β | 2024 | β |
| Increased cholesterol synthesis drives neurotoxicity in patient stem cell-derived model of multiple sclerosis. | Ionescu RB et al. | β | 2024 | β |
| In-depth analysis of transcriptomes in ovarian cortical follicles from children and adults reveals interfollicular heterogeneity. | Rooda I et al. | β | 2024 | β |
| Induced Pluripotent Stem Cell-Derived Parathyroid Organoids Resemble Parathyroid Morphology and Function. | Εenkal-Turhan S et al. | β | 2024 | β |
| Induction of the TEAD Coactivator VGLL1 by Estrogen Receptor-Targeted Therapy Drives Resistance in Breast Cancer. | Gemma C et al. | β | 2024 | β |
| <i>Nf1</i> deficiency modulates the stromal environment in the pretumorigenic rat mammary gland. | Arumugam M et al. | β | 2024 | β |
| Inference of essential genes in <i>Brugia malayi</i> and <i>Onchocerca volvulus</i> by machine learning and the implications for discovering new interventions. | Campos TL et al. | β | 2024 | β |
| Inference of Essential Genes of the Parasite <i>Haemonchus contortus</i> via Machine Learning. | Campos TL et al. | β | 2024 | β |
| Inferring single-cell resolution spatial gene expression via fusing spot-based spatial transcriptomics, location, and histology using GCN. | Xue S et al. | β | 2024 | β |
| Inhibiting EZH2 targets atypical teratoid rhabdoid tumor by triggering viral mimicry via both RNA and DNA sensing pathways. | Feng S et al. | β | 2024 | β |
| Innate immune memory after brain injury drives inflammatory cardiac dysfunction. | Simats A et al. | β | 2024 | β |
| Integrated enhancer regulatory network by enhancer-promoter looping in gastric cancer. | Zhu T et al. | β | 2024 | β |
| Integrated multi-omics approach reveals the role of striated muscle preferentially expressed protein kinase in skeletal muscle including its relationship with myospryn complex. | Li Q et al. | β | 2024 | β |
| Integrated proteomic and transcriptomic landscape of human placenta in small for gestational age infants. | Jin H et al. | β | 2024 | β |
| Integrated proteomics and metabolomics analyses reveal new insights into the antitumor effects of valproic acid plus simvastatin combination in a prostate cancer xenograft model associated with downmodulation of YAP/TAZ signaling. | Iannelli F et al. | β | 2024 | β |
| Integrated proteomics and transcriptomics analysis reveals insights into differences in premature mortality associated with disparate pathogenic RBM20 variants. | Gregorich ZR et al. | β | 2024 | β |
| Integration of ssGWAS and ROH analyses for uncovering genetic variants associated with reproduction traits in Large White pigs. | Zhang Z et al. | β | 2024 | β |
| Integrative analysis in head and neck cancer reveals distinct role of miRNome and methylome as tumour epigenetic drivers. | MandiΔ K et al. | β | 2024 | β |
| Integrative analysis of multi-omics data reveals importance of collagen and the PI3K AKT signalling pathway in CAKUT. | Bayjanov JR et al. | β | 2024 | β |
| Integrative analysis reveals novel insights into juvenile idiopathic arthritis pathogenesis and shared molecular pathways with associated traits. | Pudjihartono N et al. | β | 2024 | β |
| Integrative metabolomics-genomics analysis identifies key networks in a stem cell-based model of schizophrenia. | Spathopoulou A et al. | β | 2024 | β |
| Integrative single-cell RNA-seq and spatial transcriptomics analyses reveal diverse apoptosis-related gene expression profiles in EGFR-mutated lung cancer. | Izumi M et al. | β | 2024 | β |
| Intercellular extrachromosomal DNA copy-number heterogeneity drives neuroblastoma cell state diversity. | StΓΆber MC et al. | β | 2024 | β |
| Iron transport pathways in the human malaria parasite <i>Plasmodium falciparum</i> revealed by RNA-sequencing. | Wunderlich J et al. | β | 2024 | β |
| <i>Slc4a7</i> Regulates Retina Development in Zebrafish. | Zhuang Y et al. | β | 2024 | β |
| Landscape transcriptomic analysis of bovine follicular cells during key phases of ovarian follicular development. | MogollΓ³n GarcΓa HD et al. | β | 2024 | β |
| Large-scale copy number alterations are enriched for synthetic viability in BRCA1/BRCA2 tumors. | Zhu Y et al. | β | 2024 | β |
| Large-scale single-nuclei profiling identifies role for ATRNL1 in atrial fibrillation. | Hill MC et al. | β | 2024 | β |
| Lateral root enriched Massilia associated with plant flowering in maize. | Wang D et al. | β | 2024 | β |
| L-Glyceraldehyde Inhibits Neuroblastoma Cell Growth via a Multi-Modal Mechanism on Metabolism and Signaling. | Forbes M et al. | β | 2024 | β |
| LINC02257 regulates malignant phenotypes of colorectal cancer via interacting with miR-1273g-3p and YB1. | Park MS et al. | β | 2024 | β |
| Linking pesticide exposure to neurodegenerative diseases: An in vitro investigation with human neuroblastoma cells. | Alehashem M et al. | β | 2024 | β |
| lncRNA-gene network analysis reveals the effects of early maternal nutrition on mineral homeostasis and energy metabolism in the fetal liver transcriptome of beef heifers. | Anas M et al. | β | 2024 | β |
| Local administration of regulatory T cells promotes tissue healing. | Nayer B et al. | β | 2024 | β |
| Loss of LPAR6 and CAB39L dysregulates the basal-to-luminal urothelial differentiation program, contributing to bladder carcinogenesis. | Lee S et al. | β | 2024 | β |
| Loss of miR-145 promotes remyelination and functional recovery in a model of chronic central demyelination. | Kornfeld SF et al. | β | 2024 | β |
| Loss of Notch dimerization perturbs intestinal homeostasis by a mechanism involving HDAC activity. | Dai Q et al. | β | 2024 | β |
| Lysozyme 1 Inflamed CCR2<sup>+</sup> Macrophages Promote Obesity-Induced Cardiac Dysfunction. | Zhang L et al. | β | 2024 | β |
| Male-specific behavioral and transcriptomic changes in aging <i>C.Β elegans</i> neurons. | Weng Y et al. | β | 2024 | β |
| Manipulation of ion/electron carrier genes in the model diatom <i>Phaeodactylum tricornutum</i> enables its growth under lethal acidic stress. | Su Y et al. | β | 2024 | β |
| Mapping the global interactome of the ARF family reveals spatial organization in cellular signaling pathways. | Quirion L et al. | β | 2024 | β |
| Mass Spectrometric and Artificial Intelligence-Based Identification of the Secretome of Plasmodium falciparum Merozoites to Provide Novel Candidates for Vaccine Development Pipeline. | Munjal A et al. | β | 2024 | β |
| MAZ promotes thyroid cancer progression by driving transcriptional reprogram and enhancing ERK1/2 activation. | Zeng J et al. | β | 2024 | β |
| Mechanically induced localisation of SECONDARY WALL INTERACTING bZIP is associated with thigmomorphogenic and secondary cell wall gene expression. | Coomey JH et al. | β | 2024 | β |
| Mechanism-free repurposing of drugs for C9orf72-related ALS/FTD using large-scale genomic data. | Saez-Atienzar S et al. | β | 2024 | β |
| Mechanism investigation of anti-NAFLD of Shugan Yipi Granule based on network pharmacology analysis and experimental verification. | Li H et al. | β | 2024 | β |
| Membrane protein Bcsdr2 mediates biofilm integrity, hyphal growth and virulence of Botrytis cinerea. | Zhang W et al. | β | 2024 | β |
| Meta-analysis of retinal transcriptome profiling studies in animal models of myopia. | Palumaa T et al. | β | 2024 | β |
| Metabolic engineering-induced transcriptome reprogramming of lipid biosynthesis enhances oil composition in oat. | Zhou Z et al. | β | 2024 | β |
| Metabolic states influence chicken retinal pigment epithelium cell fate decisions. | Perez-Estrada JR et al. | β | 2024 | β |
| Metformin induces ZFP36 by mTORC1 inhibition in cervical cancer-derived cell lines. | De la Cruz-LΓ³pez KG et al. | β | 2024 | β |
| MIMR: Development of a Web-Based System for miRNA and mRNA Integrated Analysis. | Kim D et al. | β | 2024 | β |
| miR-1, miR-133a, miR-29b and skeletal muscle fibrosis in chronic limb-threatening ischaemia. | Keane AJ et al. | β | 2024 | β |
| miR-9-5p is Downregulated in Serum Extracellular Vesicles of Patients Treated with Biperiden After Traumatic Brain Injury. | Villena-Rueda BE et al. | β | 2024 | β |
| Molecular Alterations Associated with Histologically Overt Stromal Response in Patients with Prostate Cancer. | Sayan M et al. | β | 2024 | β |
| Molecular Impact of Sublethal Spinetoram Exposure on Honeybee (<i>Apis mellifera</i>) Larval and Adult Transcriptomes. | Vasamsetti BMK et al. | β | 2024 | β |
| Molecular interplay between the upregulated levels of Sad1 and UNC84 Domain Containing 2 (SUN2) and gene expression in medulloblastoma cells. | Tecalco-Cruz AC et al. | β | 2024 | β |
| Mono-methylated histones control PARP-1 in chromatin and transcription. | Bamgbose G et al. | β | 2024 | β |
| MUFFIN: a suite of tools for the analysis of functional sequencing data. | de Langen P et al. | β | 2024 | β |
| mulea: An R package for enrichment analysis using multiple ontologies and empirical false discovery rate. | Turek C et al. | β | 2024 | β |
| Multi-omic analysis of Huntington's disease reveals a compensatory astrocyte state. | Paryani F et al. | β | 2024 | β |
| Multi-omic profiling of pathogen-stimulated primary immune cells. | Salz R et al. | β | 2024 | β |
| Multi-omics analysis reveals interactions between host and microbes in Bama miniature pigs during weaning. | Ma W et al. | β | 2024 | β |
| Multi-omics investigation of spontaneous T2DM macaque emphasizes gut microbiota could up-regulate the absorption of excess palmitic acid in the T2DM progression | Liu X et al. | β | 2024 | β |
| Multi-omics profiling combined with molecular docking reveals immune-inflammatory proteins as potential drug targets in colorectal cancer. | Dong X et al. | β | 2024 | β |
| Multiple lines of evidence for disruption of nuclear lamina and nucleoporins in FUS amyotrophic lateral sclerosis. | Okada K et al. | β | 2024 | β |
| MultiRNAflow: integrated analysis of temporal RNA-seq data with multiple biological conditions. | Loubaton R et al. | β | 2024 | β |
| Mutations in fibronectin dysregulate chondrogenesis in skeletal dysplasia. | Dinesh NEH et al. | β | 2024 | β |
| MYCT1 controls environmental sensing in human haematopoietic stem cells. | AguadΓ©-GorgoriΓ³ J et al. | β | 2024 | β |
| Network-Based Drug Repurposing and Genomic Analysis to Unveil Potential Therapeutics for Monkeypox Virus. | Rabaan AA et al. | β | 2024 | β |
| Neuronal activity-driven O-GlcNAcylation promotes mitochondrial plasticity. | Yu SB et al. | β | 2024 | β |
| Neutrophil Elastase Targets Select Proteins on Human Blood-Monocyte-Derived Macrophage Cell Surfaces. | Ahmed NT et al. | β | 2024 | β |
| Neutrophil immune profile guides spinal cord regeneration in zebrafish. | de Sena-TomΓ‘s C et al. | β | 2024 | β |
| New insight into the development of synpolydactyly caused by expansion of HOXD13 polyalanine based on weighted gene co-expression network analysis. | Chen X et al. | β | 2024 | β |
| NKG2C/<i>KLRC2</i> tumor cell expression enhances immunotherapeutic efficacy against glioblastoma. | de Dios O et al. | β | 2024 | β |
| Non-invasive prediction of preeclampsia using the maternal plasma cell-free DNA profile and clinical risk factors. | Yu Y et al. | β | 2024 | β |
| Novel drug resistance mechanisms and drug targets in BRAF-mutated peritoneal metastasis from colorectal cancer. | Lund-Andersen C et al. | β | 2024 | β |
| Novel formylpeptide receptor 1/2 agonist limits hypertension-induced cardiovascular damage. | Singh J et al. | β | 2024 | β |
| Novel pathways linked to the expression of temperament in Merino sheep: a genome-wide association study. | Ding L et al. | β | 2024 | β |
| O-GlcNAcylation controls pro-fibrotic transcriptional regulatory signaling in myofibroblasts. | Very N et al. | β | 2024 | β |
| Oncogenic Cell Tagging and Single-Cell Transcriptomics Reveal Cell Type-Specific and Time-Resolved Responses to Vhl Inactivation in the Kidney. | Kurlekar S et al. | β | 2024 | β |
| Oncogenic plasmid DNA and liver injury agent dictates liver cancer development in a mouse model. | Chiu V et al. | β | 2024 | β |
| Overactive mitochondrial DNA replication disrupts perinatal cardiac maturation. | Landoni JC et al. | β | 2024 | β |
| OVO positively regulates essential maternal pathways by binding near the transcriptional start sites in the <i>Drosophila</i> female germline. | Benner L et al. | β | 2024 | β |
| Parsing the effect of co-culture with brain organoids on Diffuse Intrinsic Pontine Glioma (DIPG) using quantitative proteomics. | Prior VG et al. | β | 2024 | β |
| Perturbation of the insomnia WDR90 genome-wide association studies locus pinpoints rs3752495 as a causal variant influencing distal expression of neighboring gene, PIG-Q. | Sonti S et al. | β | 2024 | β |
| Phenotype prediction in plants is improved by integrating large-scale transcriptomic datasets. | Wu Z et al. | β | 2024 | β |
| Phosphoproteomic changes in response to anoxia are tissue-specific in the anoxia-tolerant crucian carp (<i>Carassius carassius</i>). | Johansen A et al. | β | 2024 | β |
| Photothermal Temperature-Modulated Cancer Metastasis Harnessed Using Proteinase-Triggered Assembly of Near-Infrared II Photoacoustic/Photothermal Nanotheranostics. | Chuang YC et al. | β | 2024 | β |
| PI3KΞ³ inhibition circumvents inflammation and vascular leak in SARS-CoV-2 and other infections. | Shepard RM et al. | β | 2024 | β |
| Placental Transcriptomic Signatures of Prenatal Phthalate Exposure and Identification of Placenta-Brain Genes Associated with the Effects of Phthalate Exposure on Neurodevelopment in Children. | Ren J et al. | β | 2024 | β |
| Plasma proteomic profiling reveals that SERPINE1 is a potential biomarker associated with coronary artery lesions in Kawasaki disease. | Wang N et al. | β | 2024 | β |
| Pleiotropic effects of PAB1 deletion: Extensive changes in the yeast proteome, transcriptome, and translatome. | Mangkalaphiban K et al. | β | 2024 | β |
| Post-translational modification-centric base editor screens to assess phosphorylation site functionality in high throughput. | Kennedy PH et al. | β | 2024 | β |
| PPARG in osteocytes controls cell bioenergetics and systemic energy metabolism independently of sclerostin levels in circulation. | Baroi S et al. | β | 2024 | β |
| Predicting gene disease associations with knowledge graph embeddings for diseases with curtailed information. | Gualdi F et al. | β | 2024 | β |
| Predicting human and viral protein variants affecting COVID-19 susceptibility and repurposing therapeutics. | Waman VP et al. | β | 2024 | β |
| Predicting somatic mutation origins in cell-free DNA by semi-supervised GAN models. | Palizban F et al. | β | 2024 | β |
| Prediction of m6A and m5C at single-molecule resolution reveals a transcriptome-wide co-occurrence of RNA modifications. | Acera Mateos P et al. | β | 2024 | β |
| Prevalence of and gene regulatory constraints on transcriptional adaptation in single cells. | Mellis IA et al. | β | 2024 | β |
| Profiling muscle transcriptome in mice exposed to microgravity using gene set enrichment analysis. | Oommen AM et al. | β | 2024 | β |
| Proposing candidate genes under telomeric control based on cross-species position data. | Projahn EF et al. | β | 2024 | β |
| Prostaglandin D2 receptor 2 downstream signaling and modulation of type 2 innate lymphoid cells from patients with asthma. | Gress C et al. | β | 2024 | β |
| Prostate cancer detection through unbiased capture of methylated cell-free DNA. | Lleshi E et al. | β | 2024 | β |
| Prostate cancer reshapes the secreted and extracellular vesicle urinary proteomes. | Khoo A et al. | β | 2024 | β |
| Proteomic Analysis Identifies Multiple Mechanisms of 5-Fluorouracil-Induced Gut Mucositis in Mice. | Ivanov SM et al. | β | 2024 | β |
| Proteomic analysis of sperm from fertile stallions and subfertile stallions due to impaired acrosomal exocytosis. | HernΓ‘ndez-AvilΓ©s C et al. | β | 2024 | β |
| Proteomic insights into extracellular vesicles in ALS for therapeutic potential of Ropinirole and biomarker discovery. | Kato C et al. | β | 2024 | β |
| Protocol for analysis of plasma proteomes from patients with hepatocellular carcinoma receiving combination therapy. | Pan ZF et al. | β | 2024 | β |
| Reduced Expression of Oligodendrocyte Linage-Enriched Transcripts During the Endoplasmic Reticulum Stress/Integrated Stress Response. | Gao Y et al. | β | 2024 | β |
| Refinement of rice blast disease resistance QTLs and gene networks through meta-QTL analysis. | Devanna BN et al. | β | 2024 | β |
| Remodeling of the epigenetic landscape in rainbow trout, Oncorhynchus mykiss, offspring in response to maternal choline intake. | Freij K et al. | β | 2024 | β |
| Repetitive element transcript accumulation is associated with inflammaging in humans. | Smith ME et al. | β | 2024 | β |
| Reported race-associated differences in control and schizophrenia post-mortem brain transcriptomes implicate stress-related and neuroimmune pathways. | Simmons S et al. | β | 2024 | β |
| Representing core gene expression activity relationships using the latent structure implicit in Bayesian networks. | Gao J et al. | β | 2024 | β |
| RFC2 may contribute to the pathogenicity of Williams syndrome revealed in a zebrafish model. | Park JW et al. | β | 2024 | β |
| RNA editing regulates host immune response and T cell homeostasis in SARS-CoV-2 infection. | Huang M et al. | β | 2024 | β |
| RNA sequencing provides novel insights into the pathogenesis of naturally occurring myxomatous mitral valve disease stage B1 in beagle dogs. | Kim TS et al. | β | 2024 | β |
| Roles of SNORD115 and SNORD116 ncRNA clusters during neuronal differentiation. | Helwak A et al. | β | 2024 | β |
| Runx3, Brn3a and Isl1 interplay orchestrates the transcriptional program in the early stages of proprioceptive neuron development. | Orlovsky K et al. | β | 2024 | β |
| Safety Assessment of Camelid-Derived Single-Domain Antibody as Feed Additive for Juvenile Whiteleg Shrimp (<i>Litopenaeus vannamei</i>) Against White Spot Syndrome Virus. | Aulia D et al. | β | 2024 | β |
| SARS-CoV-2 infection modifies the transcriptome of the megakaryocytes in the bone marrow. | Allaeys I et al. | β | 2024 | β |
| Sex-Differential Gene Expression in Developing Human Cortex and Its Intersection With Autism Risk Pathways. | Kissel LT et al. | β | 2024 | β |
| Sexually selected differences in warbler plumage are related to a putative inversion on the Z chromosome. | Dunn PO et al. | β | 2024 | β |
| SHH Signaling as a Key Player in Endometrial Cancer: Unveiling the Correlation with Good Prognosis, Low Proliferation, and Anti-Tumor Immune Milieu. | Snijesh VP et al. | β | 2024 | β |
| Signals of positive selection in genomes of palearctic Myotis-bats coexisting with a fungal pathogen. | Twort VG et al. | β | 2024 | β |
| Single-cell and spatially resolved interactomics of tooth-associated keratinocytes in periodontitis. | Easter QT et al. | β | 2024 | β |
| Single cell dual-omic atlas of the human developing retina. | Zuo Z et al. | β | 2024 | β |
| Single-cell genomics and regulatory networks for 388 human brains. | Emani PS et al. | β | 2024 | β |
| Single-cell RNA-sequencing of BK polyomavirus replication in primary human renal proximal tubular epithelial cells identifies specific transcriptome signatures and a novel mitochondrial stress pattern. | Weissbach FH et al. | β | 2024 | β |
| Single-cell transcriptomics by clinical course of Mycobacterium avium complex pulmonary disease. | Kim SY et al. | β | 2024 | β |
| Single episode of moderate to severe traumatic brain injury leads to chronic neurological deficits and Alzheimer's-like pathological dementia. | Vaibhav K et al. | β | 2024 | β |
| Single-nucleus sequencing reveals enriched expression of genetic risk factors in extratelencephalic neurons sensitive to degeneration in ALS. | Limone F et al. | β | 2024 | β |
| Single-plant-omics reveals the cascade of transcriptional changes during the vegetative-to-reproductive transition. | Redmond EJ et al. | β | 2024 | β |
| SLMAP3 is crucial for organogenesis through mechanisms involving primary cilia formation. | Dias AP et al. | β | 2024 | β |
| Spiral ganglion neuron degeneration in aminoglycoside-deafened rats involves innate and adaptive immune responses not requiring complement. | Gansemer BM et al. | β | 2024 | β |
| Statistical Testing for Protein Equivalence Identifies Core Functional Modules Conserved across 360 Cancer Cell Lines and Presents a General Approach to Investigating Biological Systems. | Ergin EK et al. | β | 2024 | β |
| Stellate cells are in utero markers of pancreatic disease in cystic fibrosis. | Leir SH et al. | β | 2024 | β |
| Stress-induced epigenetic effects driven by maternal lactation in dairy cattle: a comethylation network approach. | LΓ³pez-Catalina A et al. | β | 2024 | β |
| Subcellular mass spectrometric detection unveils hyperglycemic memory in the diabetic heart. | Zhan J et al. | β | 2024 | β |
| Supplementation with a Whey Protein Concentrate Enriched in Bovine Milk Exosomes Improves Longitudinal Growth and Supports Bone Health During Catch-Up Growth in Rats. | GarcΓa-MartΓnez J et al. | β | 2024 | β |
| Swim training induces distinct osseous gene expression patterns in anosteocytic and osteocytic teleost fish. | Tauer JT et al. | β | 2024 | β |
| Synaptic plasticity in human thalamocortical assembloids. | Patton MH et al. | β | 2024 | β |
| Systematic identification of structure-specific protein-protein interactions. | Holfeld A et al. | β | 2024 | β |
| Systematic mapping of mitochondrial calcium uniporter channel (MCUC)-mediated calcium signaling networks. | Delgado de la Herran H et al. | β | 2024 | β |
| Tail-anchored membrane protein SLMAP3 is essential for targeting centrosomal proteins to the nuclear envelope in skeletal myogenesis. | Dias AP et al. | β | 2024 | β |
| Temporal changes in mouse hippocampus transcriptome after pilocarpine-induced seizures. | Popova EY et al. | β | 2024 | β |
| TET3 regulates terminal cell differentiation at the metabolic level. | Mulet I et al. | β | 2024 | β |
| The association between cumulative exposure to PM<sub>2.5</sub> and DNA methylation measured using methyl-capture sequencing among COPD patients. | Ji HW et al. | β | 2024 | β |
| The emerging H3K9me3 chromatin landscape during zebrafish embryogenesis. | Duval KL et al. | β | 2024 | β |
| The endophytic fungus Serendipita indica affects auxin distribution in Arabidopsis thaliana roots through alteration of auxin transport and conjugation to promote plant growth. | GonzΓ‘lez Ortega-VillaizΓ‘n A et al. | β | 2024 | β |
| The FERONIA-RESPONSIVE TO DESICCATION 26 module regulates vascular immunity to Ralstonia solanacearum. | Wang B et al. | β | 2024 | β |
| The genome-wide response of Dermatophagoides pteronyssinus to cystatin A, a peptidase inhibitor from human skin, sheds light on its digestive physiology and allergenicity. | Vidal-Quist JC et al. | β | 2024 | β |
| The genomic landscape of MΓ©niΓ¨re's disease: a path to endolymphatic hydrops. | Fisch KM et al. | β | 2024 | β |
| The gut microbiota and its metabolite butyrate shape metabolism and antiviral immunity along the gut-lung axis in the chicken. | Saint-Martin V et al. | β | 2024 | β |
| The H3K4 demethylase JMJ1 is required for proper timing of flowering in Brachypodium distachyon. | Liu B et al. | β | 2024 | β |
| The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in p53 proficient colon cancer cells. | SlaninovΓ‘ V et al. | β | 2024 | β |
| The mitochondrial multi-omic response to exercise training across rat tissues. | Amar D et al. | β | 2024 | β |
| The Molecular Landscape of Premature Aging Diseases Defined by Multilayer Network Exploration. | Beust C et al. | β | 2024 | β |
| The neuron-specific IIS/FOXO transcriptome in aged animals reveals regulatory mechanisms of cognitive aging. | Weng Y et al. | β | 2024 | β |
| The P2Y6 Receptor as a Potential Keystone in Essential Hypertension. | Daghbouche-Rubio N et al. | β | 2024 | β |
| The pRb/RBL2-E2F1/4-GCN5 axis regulates cancer stem cell formation and G0 phase entry/exit by paracrine mechanisms. | Chang CH et al. | β | 2024 | β |
| The Rice Online Expression Profiles Array Database Version 2 (ROADv2): An Interactive Atlas for Rice Functional Genomics. | Hwang W et al. | β | 2024 | β |
| The role of corticosterone in nevirapine-induced idiosyncratic drug-induced liver injury. | Jee A et al. | β | 2024 | β |
| The transcriptome landscape of developing barley seeds. | Kovacik M et al. | β | 2024 | β |
| THI1 Gene Evolutionary Trends: A Comprehensive Plant-Focused Assessment via Data Mining and Large-Scale Analysis. | Dias HM et al. | β | 2024 | β |
| Time- and cell-specific activation of BMP signaling restrains chondrocyte hypertrophy. | Gadomski SJ et al. | β | 2024 | β |
| Transcriptome Analysis of Rice Root Tips Reveals Auxin, Gibberellin and Ethylene Signaling Underlying Nutritropism. | Yamazaki K et al. | β | 2024 | β |
| Transcriptome profiling of two rice varieties reveals their molecular responses under high night-time temperature. | Mustahsan WK et al. | β | 2024 | β |
| Transcriptome-wide analysis uncovers regulatory elements of the antennal transcriptome repertoire of bumblebee at different life stages. | Dikmen F et al. | β | 2024 | β |
| Transcriptomic Analyses Reveal That <i>Coffea arabica</i> and <i>Coffea canephora</i> Have More Complex Responses under Combined Heat and Drought than under Individual Stressors. | Marques I et al. | β | 2024 | β |
| Transcriptomic Analysis of Newborn Hanwoo Calves: Effects of Maternal Overnutrition during Mid- to Late Pregnancy on Subcutaneous Adipose Tissue and Liver. | Shokrollahi B et al. | β | 2024 | β |
| Transcriptomic analysis of rat prefrontal cortex following chronic stress induced by social isolation - Relevance to psychiatric and neurodevelopmental illness, and implications for treatment. | Goh JY et al. | β | 2024 | β |
| Transcriptomic and de novo proteomic analyses of organotypic entorhino-hippocampal tissue cultures reveal changes in metabolic and signaling regulators in TTX-induced synaptic plasticity. | Lenz M et al. | β | 2024 | β |
| Transcriptomic and epigenetic responses shed light on soybean resistance to Phytophthora sansomeana. | Lee G et al. | β | 2024 | β |
| Transcriptomic and Methylomic Analyses Show Significant Shifts in Biosynthetic Processes and Reduced Intrapopulation Gene Expression Variance in PAH-Adapted Atlantic Killifish. | Harishchandra A et al. | β | 2024 | β |
| Transcriptomic changes in the posterior pallium of male zebra finches associated with social niche conformance. | Riyahi S et al. | β | 2024 | β |
| Transcriptomic profiling of day 3 human embryos of poor quality reveals molecular links to divergent developmental trajectories. | Li Y et al. | β | 2024 | β |
| Transcriptomic sex differences in postmortem brain samples from patients with psychiatric disorders. | Xia Y et al. | β | 2024 | β |
| Translatome profiling reveals Itih4 as a novel smooth muscle cell-specific gene in atherosclerosis. | Ravindran A et al. | β | 2024 | β |
| Transplacental Transfer of Oxytocin and Its Impact on Neonatal Cord Blood and In Vitro Retinal Cell Activity. | Adegboro CO et al. | β | 2024 | β |
| Type II innate lymphoid cell plasticity contributes to impaired reconstitution after allogeneic hematopoietic stem cell transplantation. | Laurie SJ et al. | β | 2024 | β |
| Uncovering the BIN1-SH3 interactome underpinning centronuclear myopathy. | Zambo B et al. | β | 2024 | β |
| Understanding the function of Pax5 in development of docetaxel-resistant neuroendocrine-like prostate cancers. | Bhattacharya S et al. | β | 2024 | β |
| Understanding the Molecular Mechanisms of Incomptine A in Treating Non-Hodgkin Lymphoma Associated with U-937 Cells: Bioinformatics Approaches, Part I. | Calzada F et al. | β | 2024 | β |
| Unique genetic and risk-factor profiles in clusters of major depressive disorder-related multimorbidity trajectories. | Gezsi A et al. | β | 2024 | β |
| Unique Splicing of <i>Lrp5</i> in the Brain: A New Player in Neurodevelopment and Brain Maturation. | Luquero A et al. | β | 2024 | β |
| Unraveling druggable cancer-driving proteins and targeted drugs using artificial intelligence and multi-omics analyses. | LΓ³pez-CortΓ©s A et al. | β | 2024 | β |
| Unveiling Genetic Potential for Equine Meat Production: A Bioinformatics Approach. | Ε imon M et al. | β | 2024 | β |
| Uridylation regulates mRNA decay directionality in fission yeast. | Grochowski M et al. | β | 2024 | β |
| Use of Transcriptional Signatures to Differentiate Pathogen-Specific and Treatment-Specific Host Responses in Patients With Bacterial Bloodstream Infections. | Thaden JT et al. | β | 2024 | β |
| Validation of metaxin-2 deficient C. elegans as a model for MandibuloAcral Dysplasia associated to mtx-2 (MADaM) syndrome. | Talarmin-Gas C et al. | β | 2024 | β |
| Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3' UTR of FAIM2. | Littleton SH et al. | β | 2024 | β |
| VDX-111 targets proliferative pathways in canine cancer cell lines. | Farrell KB et al. | β | 2024 | β |
| Whole exome sequencing analysis identifies genes for alcohol consumption. | Kang J et al. | β | 2024 | β |
| Widespread changes to the translational landscape in a maize microRNA biogenesis mutant. | Yang H et al. | β | 2024 | β |
| Worldwide analysis of actionable genomic alterations in lung cancer and targeted pharmacogenomic strategies. | EcheverrΓa-GarcΓ©s G et al. | β | 2024 | β |
| XGRm: A Web Server for Interpreting Mouse Summary-level Genomic Data. | Wang S et al. | β | 2024 | β |
| xWAS analysis in neuropsychiatric disorders by integrating multi-molecular phenotype quantitative trait loci and GWAS summary data. | Luo L et al. | β | 2024 | β |
| ZNF469 is a profibrotic regulator of extracellular matrix in hepatic stellate cells. | Ariyachet C et al. | β | 2024 | β |