Age of onset of mental disorders: a review of recent literature.
- Authors
- Kessler, Ronald C; Amminger, G Paul; Aguilar-Gaxiola, Sergio; Alonso, Jordi; Lee, Sing; Ustün, T Bedirhan
- Year
- 2007
- Journal
- Current opinion in psychiatry
- PMID
- 17551351
- DOI
- 10.1097/YCO.0b013e32816ebc8c
- PMCID
- PMC1925038
PURPOSE OF REVIEW: The aim of this article is to review recent epidemiological research on age-of-onset of mental disorders, focusing on the WHO World Mental Health surveys. RECENT FINDINGS: Median and inter-quartile range (IQR; 25th-75th percentiles) of age-of-onset is much earlier for phobias (7-14, IQR 4-20) and impulse-control disorders (7-15; IQR 4-35) than other anxiety disorders (25-53, IQR 15-75), mood disorders (25-45, IQR 17-65), and substance disorders (18-29, IQR 16-43). Although less data exist for nonaffective psychosis, available evidence suggests that median age-of-onset is in the range late teens through early 20s. Roughly half of all lifetime mental disorders in most studies start by the mid-teens and three quarters by the mid-20s. Later onsets are mostly secondary conditions. Severe disorders are typically preceded by less severe disorders that are seldom brought to clinical attention. SUMMARY: First onset of mental disorders usually occur in childhood or adolescence, although treatment typically does not occur until a number of years later. Although interventions with early incipient disorders might help reduce severity-persistence of primary disorders and prevent secondary disorders, additional research is needed on appropriate treatments for early incipient cases and on long-term evaluation of the effects of early intervention on secondary prevention.
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| Sex, ethnic and socioeconomic inequalities and trajectories in child and adolescent mental health in Australia and the UK: findings from national prospective longitudinal studies. | Terhaag S et al. | — | 2021 | → |
| Single Session and Short-Term Exercise for Mental Health Promotion in Tertiary Students: A Scoping Review. | Pascoe MC et al. | — | 2021 | → |
| Social anxiety and agoraphobia symptoms effectively treated by Prompt Mental Health Care versus TAU at 6- and 12-month follow-up: Secondary analysis from a randomized controlled trial. | Knapstad M et al. | — | 2021 | → |
| Social isolation as a core feature of adolescent depression: a qualitative study in Porto Alegre, Brazil. | Viduani A et al. | — | 2021 | → |
| Suicidality Presented to a Child and Adolescent Psychiatry Emergency Service: Increasing Rate and Changing Characteristics. | Kandsperger S et al. | — | 2021 | → |
| Supporting Student's Mental Health: A Cross-Sectional Survey for School Nurses. | Markkanen P et al. | — | 2021 | → |
| Text Message Interventions in Adolescent Mental Health and Addiction Services: Scoping Review. | MacDougall S et al. | — | 2021 | → |
| The 3D-Transition Study: Objectives, Methods, and Implementation of an Innovative Planned Missing-Data Design. | Rioux C et al. | — | 2021 | → |
| The association between depressive symptoms and self-reported sleep difficulties among college students: Truth or reporting bias? | Huang Z et al. | — | 2021 | → |
| The association between diet and mental health and wellbeing in young adults within a biopsychosocial framework. | Rossa-Roccor V et al. | — | 2021 | → |
| The Association Between Locus of Control and Psychopathology: A Cross-Cohort Comparison Between a UK (Avon Longitudinal Study of Parents and Children) and a Japanese (Tokyo Teen Cohort) Cohort. | Sullivan S et al. | — | 2021 | → |
| The Association Between Suicide Attempts, Anxiety, and Childhood Maltreatment Among Adolescents and Young Adults With First Depressive Episodes. | Chen H et al. | — | 2021 | → |
| The Building Educators' Skills in Adolescent Mental Health Training Program for Secondary School Educators: Protocol for a Cluster Randomized Controlled Trial. | Parker BL et al. | — | 2021 | → |
| The burden of mental disorder in Sierra Leone: a retrospective observational evaluation of programmatic data from the roll out of decentralised nurse-led mental health units. | Hopwood H et al. | — | 2021 | → |
| The CAMP study: feasibility and clinical correlates of standardized assessments of substance use in a youth psychiatric inpatient sample. | Halladay J et al. | — | 2021 | → |
| The effects of in-utero exposure to influenza on mental health and mortality risk throughout the life-course. | Turner AJ et al. | — | 2021 | → |
| The effects of mental health problems in childhood and adolescence in young adults: Results of the KiGGS cohort. | Schlack R et al. | — | 2021 | → |
| The Histaminergic System in Neuropsychiatric Disorders. | Cheng L et al. | — | 2021 | → |
| The Impact of COVID-19 and Associated Interventions on Mental Health: A Cross-Sectional Study in a Sample of University Students. | Camilleri C et al. | — | 2021 | → |
| The integration of mental health care act in primary care: an audit of the use of mental health care act forms for patients´ admission and the effect of continuing medical education on health professionals´ performance of usage, based on Letsholathebe II Memorial Hospital´s experience, in Maun, Botswana. | Mbuka DO et al. | — | 2021 | → |
| The predictive capacity of psychiatric and psychological polygenic risk scores for distinguishing cases in a child and adolescent psychiatric sample from controls. | Jansen AG et al. | — | 2021 | → |
| The prevalence of mental health problems in sub-Saharan adolescents: A systematic review. | Jörns-Presentati A et al. | — | 2021 | → |
| The Relationship Between Abnormal Resting-State Functional Connectivity of the Left Superior Frontal Gyrus and Cognitive Impairments in Youth-Onset Drug-Naïve Schizophrenia. | Qiu X et al. | — | 2021 | → |
| The Relationship between Family Meals and Mental Health Problems in Japanese Elementary School Children: A Cross-Sectional Study. | Kameyama N et al. | — | 2021 | → |
| The use of coping strategies "shift-persist" mediates associations between physical activity and mental health problems in adolescents: a cross-sectional study. | Dahlstrand J et al. | — | 2021 | → |
| The use of first-generation long-acting injectable antipsychotics in children and adolescents-A retrospective audit from India. | Jacob P et al. | — | 2021 | → |
| The youth online training and employment system: Study protocol for a randomized controlled trial of an online vocational intervention for young people with mental ill health. | Simmons MB et al. | — | 2021 | → |
| Time trends in adolescent mental wellbeing in the Czech Republic between 2002 and 2018: gender, age and socioeconomic differences. | Cosma A et al. | — | 2021 | → |
| Toxoplasma gondii, Herpesviridae and long-term risk of transition to first-episode psychosis in an ultra high-risk sample. | Burkhardt E et al. | — | 2021 | → |
| Trends in the utilization of youth primary healthcare services and psychological distress. | Potrebny T et al. | — | 2021 | → |
| Understanding the Connection Between the Gut-Brain Axis and Stress/Anxiety Disorders. | Lee Y et al. | — | 2021 | → |
| Understanding University Students' Experiences, Perceptions, and Attitudes Toward Peers Displaying Mental Health-Related Problems on Social Networking Sites: Online Survey and Interview Study. | Kim T et al. | — | 2021 | → |
| Validation of a Kazakhstani Version of the Mental Health Continuum-Short Form. | Hernández-Torrano D et al. | — | 2021 | → |
| Youth in a pandemic: a longitudinal examination of youth mental health and substance use concerns during COVID-19. | Hawke LD et al. | — | 2021 | → |
| Zoom or In-Person: An Ecological Momentary Assessment Study of Time with Friends and Depressive Symptoms on Affect in Emerging Adults. | Kesselring I et al. | — | 2021 | → |
| Evidence for Specific Associations Between Depressive Symptoms, Psychotic Experiences, and Suicidal Ideation in Chilean Adolescents From the General Population. | Núñez D et al. | — | 2020 | → |
| Local, Early, and Precise: Designing a Clinical Decision Support System for Child and Adolescent Mental Health Services. | Røst TB et al. | — | 2020 | → |
| Perceived Stress Scale Among Adolescents with Polycystic Ovary Syndrome. | Khafagy G et al. | — | 2020 | → |
| Positive Youth Development in Croatia: School and Family Factors Associated With Mental Health of Croatian Adolescents. | Novak M et al. | — | 2020 | → |
| Prevalence of Mental Health Disorders among Individuals Enrolled in an Emergency Response Program for Treatment of Opioid Use Disorder. | Bakos-Block C et al. | — | 2020 | → |
| The persistence of child and adolescence mental healthcare: results from registry data. | Dijk HH et al. | — | 2020 | → |
| Worried, weary and worn out: mixed-method study of stress and well-being in final-year medical students. | Lane A et al. | — | 2020 | → |