Personal genomes: The case of the missing heritability.
paper
Cited
Public
Unavailable
- Authors
- Maher, Brendan
- Year
- 2008
- Journal
- Nature
- PMID
- 18987709
- DOI
- 10.1038/456018a
No figures extracted from this document.
No chunks β full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Integrated Cross-Platform Analysis Reveals Candidate Variants and Linkage Disequilibrium-Defined Loci Associated with Osteoporosis in Korean Postmenopausal Women. | Kim SK et al. | β | 2026 | β |
| Natural variation suggests candidate genes underlying Caenorhabditis elegans susceptibility to diverse toxicants. | Crombie TA et al. | β | 2026 | β |
| On modeling the shared environment. | Asefa H et al. | β | 2026 | β |
| Personality Genomics. | Schwaba T et al. | β | 2026 | β |
| Quantifying microbiota impact on plant traits for the guidance of breeding programs. | Blouin M et al. | β | 2026 | β |
| Alzheimer disease is (sometimes) highly heritable: Drivers of variation in heritability estimates for binary traits, a systematic review. | Liu S et al. | β | 2025 | β |
| A mathematical framework for the quantitative analysis of genetic buffering. | Karagiannis J | β | 2025 | β |
| A one-shot, lossless algorithm for cross-cohort learning in mixed-outcomes analysis. | Li R et al. | β | 2025 | β |
| A rare variant in <i>GPR156</i> associated with depression in a Mennonite pedigree causes habenula hyperactivity and stress sensitivity in mice. | Miller BR et al. | β | 2025 | β |
| Comparing genomic studies in animal breeding and human genetics: focus on disease-related traits in livestock - A review. | Gervais O et al. | β | 2025 | β |
| Crosstalk between T cell gene regulation and intestinal epithelial cells: Insights into mucosal immunity. | Bordoni D et al. | β | 2025 | β |
| Genetic susceptibility to lung squamous cell carcinoma: new insights on 9q33.2 variants and tobacco smoking. | Ma H et al. | β | 2025 | β |
| Germline predisposition in multiple myeloma. | Martins Rodrigues F et al. | β | 2025 | β |
| High-precision machine learning identifies a reproducible functional connectivity signature of autism spectrum diagnosis in a subset of individuals. | Clarke N et al. | β | 2025 | β |
| Interactions between multiple serum metals and genetic variants for type 2 diabetes risk: A prospective Chinese cohort study. | Shen B et al. | β | 2025 | β |
| Limitations of genomics to predict and treat autism: a disorder born in the womb. | Ben-Ari Y et al. | β | 2025 | β |
| <i>Drosophila melanogaster</i> as a neurobehavioral model for sex differences in stress response. | Tawa E et al. | β | 2025 | β |
| Multiple, Single Trait GWAS and Supervised Machine Learning Reveal the Genetic Architecture of Fraxinus excelsior Tolerance to Ash Dieback in Europe. | Doonan JM et al. | β | 2025 | β |
| Mutations of short tandem repeats explain abundant trait heritability in Arabidopsis. | Zhang ZQ et al. | β | 2025 | β |
| Performance comparison of germline variant calling tools in sporadic disease cohorts. | Song Q et al. | β | 2025 | β |
| Proteome-Wide Mendelian Randomisation Study of Adverse Perinatal Outcomes. | Daubney ER et al. | β | 2025 | β |
| Sex-specific DNA methylation marks associated with sex-biased risk of recurrence in unprovoked venous thromboembolism. | Bezerra OCL et al. | β | 2025 | β |
| Shedding Light on Antisocial Behavior Through Genetically Informed Research. | Pezzoli P et al. | β | 2025 | β |
| The polygenic and poly-environmental nature of personality. | Kandler C et al. | β | 2025 | β |
| Whole-Exome Sequencing-Based Linkage Analysis of Multiple Myeloma (MM) and Monoclonal Gammopathy of Undetermined Significance (MGUS) Pedigrees. | Clay-Gilmour AI et al. | β | 2025 | β |
| Ability of Genomic Prediction to Bi-Parent-Derived Breeding Population Using Public Data for Soybean Oil and Protein Content. | Li C et al. | β | 2024 | β |
| A field study of the molecular response of brown macroalgae to heavy metal exposure: An (epi)genetic approach. | GarcΓa-Seoane R et al. | β | 2024 | β |
| A strategy for studying epigenetic diversity in natural populations: proof of concept in poplar and oak. | Lesur I et al. | β | 2024 | β |
| BridGE: a pathway-based analysis tool for detecting genetic interactions from GWAS. | Hajiaghabozorgi M et al. | β | 2024 | β |
| Characterizing genetic pathways unique to autism spectrum disorder at multiple levels of biological analysis. | Schaffer LS et al. | β | 2024 | β |
| Computing linkage disequilibrium aware genome embeddings using autoencoders. | TaΕ G et al. | β | 2024 | β |
| Contribution of rare variants to heritability of a disease is much greater than conventionally estimated: modification of allele distribution model. | Nagao Y | β | 2024 | β |
| Current progress in understanding schizophrenia using genomics and pluripotent stem cells: A meta-analytical overview. | Choudhary A et al. | β | 2024 | β |
| Distributed transformer for high order epistasis detection in large-scale datasets. | GraΓ§a M et al. | β | 2024 | β |
| Endophenotype 2.0: updated definitions and criteria for endophenotypes of psychiatric disorders, incorporating new technologies and findings. | Liu C et al. | β | 2024 | β |
| Genome-wide exploration of genetic interactions for bladder cancer risk. | Yu EY et al. | β | 2024 | β |
| Genome-wide methylome stability and parental effects in the worldwide distributed Lombardy poplar. | Vanden Broeck A et al. | β | 2024 | β |
| Gut microbial diversity moderates polygenic risk of schizophrenia. | Zhang L et al. | β | 2024 | β |
| Identification of heat stress-related genomic regions by genome-wide association study in Solanum tuberosum. | Kaier A et al. | β | 2024 | β |
| Identification of the genetic characteristics of copy number variations in experimental specific pathogen-free ducks using whole-genome resequencing. | Li L et al. | β | 2024 | β |
| Identifying latent genetic interactions in genome-wide association studies using multiple traits. | Bass AJ et al. | β | 2024 | β |
| Increased CpG methylation at the CDH1 locus in inflamed ileal mucosa of patients with Crohn disease. | de Ponthaud C et al. | β | 2024 | β |
| Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food. | Dearden L et al. | β | 2024 | β |
| Multi-OMICS approaches in cancer biology: New era in cancer therapy. | Chakraborty S et al. | β | 2024 | β |
| Mutation protocols share with sexual reproduction the physiological role of producing genetic variation within 'constraints that deconstrain'. | King DG | β | 2024 | β |
| Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: the biology of a neglected disease. | Arron HE et al. | β | 2024 | β |
| Noncanonical inheritance of phenotypic information by protein amyloids. | Eroglu M et al. | β | 2024 | β |
| Phenome-wide analysis reveals epistatic associations between APOL1 variants and chronic kidney disease and multiple other disorders. | Adamson WE et al. | β | 2024 | β |
| PTSD biomarkers: Neuroendocrine signaling to epigenetic variants. | Sbisa A et al. | β | 2024 | β |
| Scrutinizing neurodegenerative diseases: decoding the complex genetic architectures through a multi-omics lens. | CocoΘ R et al. | β | 2024 | β |
| Self-reported neurocognitive complaints in the Swiss HIV Cohort Study: a viral genome-wide association study. | Zeeb M et al. | β | 2024 | β |
| Sex-Biased Expression and Response of microRNAs in Neurological Diseases and Neurotrauma. | Geleta U et al. | β | 2024 | β |
| Shared whole environmental etiology between Alzheimer's disease and age-related macular degeneration. | Ye S et al. | β | 2024 | β |
| Sports club participation impacts life satisfaction in adolescence: A twin study. | Dings A et al. | β | 2024 | β |
| The Geneticization of Education and Its Bioethical Implications. | Matthews LJ | β | 2024 | β |
| The interplay of ethics and genetic technologies in balancing the socialΒ valuation of the human genome in UNESCO declarations. | Gaydarska H et al. | β | 2024 | β |
| Unraveling schizophrenia's genetic complexity through advanced causal inference and chromatin 3D conformation. | Liu L et al. | β | 2024 | β |
| A systematic review and meta-analysis for the association of the insulin-like growth factor1 pathway genetic polymorphisms with colorectal cancer susceptibility. | Cheraghpour M et al. | β | 2023 | β |
| Biobank-scale methods and projections for sparse polygenic prediction from machine learning. | Raben TG et al. | β | 2023 | β |
| Clinical effects of novel susceptibility genes for beta-amyloid: a gene-based association study in the Korean population. | Kim BH et al. | β | 2023 | β |
| Concomitant Coronary Artery Disease in Identical Twins: Case Report and Systematic Literature Review. | Kamzolas O et al. | β | 2023 | β |
| DNA hypomethylation of the host tree impairs interaction with mutualistic ectomycorrhizal fungus. | Vigneaud J et al. | β | 2023 | β |
| Estimation of genetic heritabilities of human traits in case-control studies. | Hu D et al. | β | 2023 | β |
| Gene and schizophrenia in the pregenome and postgenome-wide association studies era: a bibliometric analysis and network visualization. | Zakaria WNA et al. | β | 2023 | β |
| Gene-Smoking Interaction Analysis for the Identification of Novel Asthma-Associated Genetic Factors. | Cha J et al. | β | 2023 | β |
| Genetic Associations Between Smoking- and Glaucoma-Related Traits. | Tran JH et al. | β | 2023 | β |
| Genetic Basis of Inflammatory Demyelinating Diseases of the Central Nervous System: Multiple Sclerosis and Neuromyelitis Optica Spectrum. | Ortiz GG et al. | β | 2023 | β |
| Genome-wide case-only analysis of gene-gene interactions with known Parkinson's disease risk variants reveals link between LRRK2 and SYT10. | AleknonytΔ-Resch M et al. | β | 2023 | β |
| Genomic and transcriptomic analyses reveal polygenic architecture for ecologically important traits in aspen (<i>PopulusΒ tremuloides</i> Michx.). | Riehl JFL et al. | β | 2023 | β |
| Identification of candidate genes associated with carcass component weights in commercial crossbred pigs through a combined GWAS approach. | Qiu Y et al. | β | 2023 | β |
| Identifying Genes Associated with Alzheimer's Disease Using Gene-Based Polygenic Risk Score. | Lai D et al. | β | 2023 | β |
| Identifying QTLs involved in hybrid performance and heterotic group complementarity: new GWAS models applied to factorial and admixed diallel maize hybrid panels. | Beugnot A et al. | β | 2023 | β |
| Imaging genomics: data fusion in uncovering disease heritability. | Hartmann K et al. | β | 2023 | β |
| Intermediate Molecular Phenotypes to Identify Genetic Markers of Anthracycline-Induced Cardiotoxicity Risk. | GΓ³mez-Vecino A et al. | β | 2023 | β |
| Leveraging Single-Cell Populations to Uncover the Genetic Basis of Complex Traits. | Minow MAA et al. | β | 2023 | β |
| multi-GPA-Tree: Statistical approach for pleiotropy informed and functional annotation tree guided prioritization of GWAS results. | Khatiwada A et al. | β | 2023 | β |
| Multiple Germline Events Contribute to CancerΒ Development in Patients with Li-Fraumeni Syndrome. | Subasri V et al. | β | 2023 | β |
| Neural crest E-cadherin loss drives cleft lip/palate by epigenetic modulation via pro-inflammatory gene-environment interaction. | Alvizi L et al. | β | 2023 | β |
| New historical and philosophical perspectives on quantitative genetics. | Serpico D et al. | β | 2023 | β |
| SNP-Based Heritability of Osteochondrosis Dissecans in Hanoverian Warmblood Horses. | Zimmermann E et al. | β | 2023 | β |
| The complete and fully-phased diploid genome of a male Han Chinese. | Yang C et al. | β | 2023 | β |
| Trans-Acting Genotypes Associated with mRNA Expression Affect Metabolic and Thermal Tolerance Traits. | Drown MK et al. | β | 2023 | β |
| Weighted genomic prediction for growth and carcass-related traits in Nelore cattle. | da Silva Neto JB et al. | β | 2023 | β |
| Weighted multiple testing procedures in genome-wide association studies. | Obry L et al. | β | 2023 | β |
| Why we need families in genomic research on developmental psychopathology. | Cheesman R et al. | β | 2023 | β |
| ADHD and reification: Four ways a psychiatric construct is portrayed as a disease. | Te Meerman S et al. | β | 2022 | β |
| Analysis of Tryptophan and Its Main Metabolite Kynurenine and the Risk of Multiple Cancers Based on the Bidirectional Mendelian Randomization Analysis. | Li R et al. | β | 2022 | β |
| An Evolution-Based Model of Causation for Aging-Related Diseases and Intrinsic Mortality: Explanatory Properties and Implications for Healthy Aging. | Levy G et al. | β | 2022 | β |
| A Review of Feature Selection Methods for Machine Learning-Based Disease Risk Prediction. | Pudjihartono N et al. | β | 2022 | β |
| A review of SNP heritability estimation methods. | Tang M et al. | β | 2022 | β |
| Associated regions for multiple birth in Brown Swiss and Original Braunvieh cattle on chromosomes 15 and 11. | Widmer S et al. | β | 2022 | β |
| Associating complex traits with genetic variants: polygenic risk scores, pleiotropy and endophenotypes. | Fisch GS | β | 2022 | β |
| Association of smoking and polygenic risk with the incidence of lung cancer: a prospective cohort study. | Zhang P et al. | β | 2022 | β |
| A statistical boosting framework for polygenic risk scores based on large-scale genotype data. | Klinkhammer H et al. | β | 2022 | β |
| Comparing BeadChip and WGS Genotyping: Non-Technical Failed Calling Is Attributable to Additional Variation within the Probe Target Sequence. | Gershoni M et al. | β | 2022 | β |
| Development of the Korea-Polyenvironmental Risk Score for Psychosis. | Jeon EJ et al. | β | 2022 | β |
| EpiHNet: Detecting epistasis by heterogeneous molecule network. | Wang X et al. | β | 2022 | β |
| Evaluating the detection ability of a range of epistasis detection methods on simulated data for pure and impure epistatic models. | Russ D et al. | β | 2022 | β |
| Evolutionary Origins of Metabolic Reprogramming in Cancer. | GarcΓa-Sancha N et al. | β | 2022 | β |
| From Genotype to Phenotype: Polygenic Prediction of Complex Human Traits. | Raben TG et al. | β | 2022 | β |
| From society to cells and back again: new opportunities for discovery at the biosocial interface. | McDade TW et al. | β | 2022 | β |
| Genetic Structure and Molecular Mechanisms Underlying the Formation of Tassel, Anther, and Pollen in the Male Inflorescence of Maize (<i>Zea mays</i> L.). | Wang Y et al. | β | 2022 | β |
| Genetic variation and marker-trait association affect the genomic selection prediction accuracy of soybean protein and oil content. | Sun B et al. | β | 2022 | β |
| Genome-Environment Associations, an Innovative Tool for Studying Heritable Evolutionary Adaptation in Orphan Crops and Wild Relatives. | CortΓ©s AJ et al. | β | 2022 | β |
| Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB. | Eliasen AU et al. | β | 2022 | β |
| Genomic Prediction of Complex Traits in Animal Breeding with Long Breeding History, the Dairy Cattle Case. | Weller JI | β | 2022 | β |
| Graph pangenome captures missing heritability and empowers tomato breeding. | Zhou Y et al. | β | 2022 | β |
| Half a century later and we're back where we started: How the problem of locality turned in to the problem of portability. | Matthews LJ | β | 2022 | β |
| Hazardous drinking and alcohol use disorders. | MacKillop J et al. | β | 2022 | β |
| Heritability: What's the point? What is it not for? A human genetics perspective. | Robette N et al. | β | 2022 | β |
| Identification of genetic variants influencing methylation in brain with pleiotropic effects on psychiatric disorders. | Pineda-Cirera L et al. | β | 2022 | β |
| Identification of New Biological Pathways Involved in Skin Aging From the Analysis of French Women Genome-Wide Data. | Rahmouni M et al. | β | 2022 | β |
| Identification of risk genes for Alzheimer's disease by gene embedding. | Lagisetty Y et al. | β | 2022 | β |
| Interaction between a diabetes-related methylation site (TXNIP cg19693031) and variant (GLUT1 rs841853) on fasting blood glucose levels among non-diabetics. | Tsai HH et al. | β | 2022 | β |
| Lifestyle Modifies the Diabetes-Related Metabolic Risk, Conditional on Individual Genetic Differences. | Shin J et al. | β | 2022 | β |
| Linear Mixed-Effect Models Through the Lens of Hardy-Weinberg Disequilibrium. | Zhang L et al. | β | 2022 | β |
| Missing heritability found for height. | Kuchenbaecker K | β | 2022 | β |
| Multi-omics peripheral and core regions of cancer. | Wang B et al. | β | 2022 | β |
| Omnibus testing approach for gene-based gene-gene interaction. | HΓ©bert F et al. | β | 2022 | β |
| Polygenic adaptation and negative selection across traits, years and environments in a long-lived plant species (Pinus pinaster Ait., Pinaceae). | de Miguel M et al. | β | 2022 | β |
| Protein interaction networks define the genetic architecture of preterm birth. | Uzun A et al. | β | 2022 | β |
| Rare diseases: human genome research is coming home. | Ropers HH et al. | β | 2022 | β |
| SNP-based heritability and selection analyses: Improved models and new results. | Speed D et al. | β | 2022 | β |
| The genetics of autoimmune Addison disease: past, present and future. | RΓΈyrvik EC et al. | β | 2022 | β |
| The genotype-phenotype distinction: from Mendelian genetics to 21st century biology. | Pontarotti G et al. | β | 2022 | β |
| The hMeDIP-Seq identifiedΒ <i>INPP4A</i> as a novel biomarker for eosinophilic chronic rhinosinusitis with nasal polyps. | Tan H et al. | β | 2022 | β |
| Third-generation genome sequencing implicates medium-sized structural variants in chronic schizophrenia. | Lee CC et al. | β | 2022 | β |
| Three legs of the missing heritability problem. | Matthews LJ et al. | β | 2022 | β |
| Translational relevance of forward genetic screens in animal models for the study of psychiatric disease. | Sheardown E et al. | β | 2022 | β |
| Using machine learning to identify gene interaction networks associated with breast cancer. | Liu L et al. | β | 2022 | β |
| A major QTL at the LHCGR/FSHR locus for multiple birth in Holstein cattle. | Widmer S et al. | β | 2021 | β |
| A new method for exploring gene-gene and gene-environment interactions in GWAS with tree ensemble methods and SHAP values. | Johnsen PV et al. | β | 2021 | β |
| A novel statistical method for modeling covariate effects in bisulfite sequencing derived measures of DNA methylation. | Zhao K et al. | β | 2021 | β |
| A two-stage testing strategy for detecting genesΓenvironment interactions in association studies. | Zhou J et al. | β | 2021 | β |
| Bench Research Informed by GWAS Results. | Kondratyev NV et al. | β | 2021 | β |
| Canonical correlations reveal adaptive loci and phenotypic responses to climate in perennial ryegrass. | Blanco-Pastor JL et al. | β | 2021 | β |
| Decoding 'Unnecessary Complexity': A Law of Complexity and a Concept of Hidden Variation Behind "Missing Heritability" in Precision Medicine. | Singh RS | β | 2021 | β |
| DNA Methylation and Type 2 Diabetes: Novel Biomarkers for Risk Assessment? | Raciti GA et al. | β | 2021 | β |
| Down-regulated RGS5 by genetic variants impairs endothelial cell function and contributes to coronary artery disease. | Li Y et al. | β | 2021 | β |
| Eating behaviour in contrasting adiposity phenotypes: Monogenic obesity and congenital generalized lipodystrophy. | Santos JL et al. | β | 2021 | β |
| Epigenetic variation in animal populations: Sources, extent, phenotypic implications, and ecological and evolutionary relevance. | Vogt G | β | 2021 | β |
| Exome-Wide Association Study Identifies FN3KRP and PGP as New Candidate Longevity Genes. | Torres GG et al. | β | 2021 | β |
| Gallstones, Body Mass Index, C-Reactive Protein, and Gallbladder Cancer: Mendelian Randomization Analysis of Chilean and European Genotype Data. | Barahona Ponce C et al. | β | 2021 | β |
| Gender Beneath the Skull: Agency, Trauma and Persisting Stereotypes in Neuroepigenetics. | Lawson-Boyd E et al. | β | 2021 | β |
| Genetic and Genome-Wide Association Analysis of Yearling Weight Gain in Israel Holstein Dairy Calves. | Gershoni M et al. | β | 2021 | β |
| Genetic Pathways and Functional Subnetworks for the Complex Nature of Bipolar Disorder in Genome-Wide Association Study. | Kuo CY et al. | β | 2021 | β |
| Genetic-variant hotspots and hotspot clusters in the human genome facilitating adaptation while increasing instability. | Long X et al. | β | 2021 | β |
| Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs. | Qiu Y et al. | β | 2021 | β |
| Genome-wide gene-smoking interaction study identified novel susceptibility loci for non-small cell lung cancer in Chinese populations. | Wang Y et al. | β | 2021 | β |
| GWAS findings improved genomic prediction accuracy of lipid profile traits: Tehran Cardiometabolic Genetic Study. | Akbarzadeh M et al. | β | 2021 | β |
| Harnessing Crop Wild Diversity for Climate Change Adaptation. | CortΓ©s AJ et al. | β | 2021 | β |
| Identification of New Rare Variants Associated With Familial Autoimmune Thyroid Diseases by Deep Sequencing of Linked Loci. | Li CW et al. | β | 2021 | β |
| Identification of Novel Genomic-Variant Patterns of OR56A5, OR52L1, and CTSD in Retinitis Pigmentosa Patients by Whole-Exome Sequencing. | Lin TY et al. | β | 2021 | β |
| Lossless integration of multiple electronic health records for identifying pleiotropy using summary statistics. | Li R et al. | β | 2021 | β |
| Missing heritability may be hiding in repeats. | Gymrek M et al. | β | 2021 | β |
| Modulating the Microbiota as a Therapeutic Intervention for Type 2 Diabetes. | Huda MN et al. | β | 2021 | β |
| Nurture might be nature: cautionary tales and proposed solutions. | Hart SA et al. | β | 2021 | β |
| Polymorphisms in the Gene Encoding Caspase 8 May Predict the Response to First-Line Platinum-Based Chemotherapy in Locally Advanced or Advanced Non-Small-Cell Lung Cancer. | Szczyrek M et al. | β | 2021 | β |
| QTL mapping in Fusarium graminearum identified an allele of FgVe1 involved in reduced aggressiveness. | Laurent B et al. | β | 2021 | β |
| Rare variants regulate expression of nearby individual genes in multiple tissues. | Li J et al. | β | 2021 | β |
| Sex-specific longitudinal association of DNA methylation with lung function. | Sunny SK et al. | β | 2021 | β |
| Smooth-threshold multivariate genetic prediction incorporating gene-environment interactions. | Ueki M et al. | β | 2021 | β |
| SNP and Haplotype Regional Heritability Mapping (SNHap-RHM): Joint Mapping of Common and Rare Variation Affecting Complex Traits. | Oppong RF et al. | β | 2021 | β |
| Stories that can't be told by SNPs; DNA methylation variation in plant populations. | Noshay JM et al. | β | 2021 | β |
| The Augmented Classical Twin Design: Incorporating Genome-Wide Identity by Descent Sharing Into Twin Studies in Order to Model Violations of the Equal Environments Assumption. | Hwang LD et al. | β | 2021 | β |
| The limits of normal approximation for adult height. | Slavskii SA et al. | β | 2021 | β |
| The Meaning of "Cause" in Genetics. | Lynch KE | β | 2021 | β |
| [The possibility of using multiple sclerosis-associated variants of the mitochondrial genome to predict the development of multiple sclerosis]. | Omarova MA et al. | β | 2021 | β |
| The practical utility of genetic screening in school settings. | Shero J et al. | β | 2021 | β |
| The shared genetic architecture between epidemiological and behavioral traits with lung cancer. | Pettit RW et al. | β | 2021 | β |
| The Shared Genetic Architectures Between Lung Cancer and Multiple Polygenic Phenotypes in Genome-Wide Association Studies. | Byun J et al. | β | 2021 | β |
| Translational biomarkers in the era of precision medicine. | Bravo-Merodio L et al. | β | 2021 | β |
| Tree 'memory': new insights on temperature-induced priming effects during early embryogenesis. | Trontin JF et al. | β | 2021 | β |
| Understanding interactions between risk factors, and assessing the utility of the additive and multiplicative models through simulations. | Diaz-Gallo LM et al. | β | 2021 | β |
| Wilson's Disease: Facing the Challenge of Diagnosing a Rare Disease. | SΓ‘nchez-Monteagudo A et al. | β | 2021 | β |
| A method for estimating coherence of molecular mechanisms in major human disease and traits. | Dozmorov MG et al. | β | 2020 | β |
| Analysis of the interaction effect of 48 SNPs and obesity on type 2 diabetes in Chinese Hans. | Liu J et al. | β | 2020 | β |
| A new efficient method to detect genetic interactions for lung cancer GWAS. | Luyapan J et al. | β | 2020 | β |
| A novel association test for rare variants based on algebraic statistics. | Meng J et al. | β | 2020 | β |
| A robust and unified framework for estimating heritability in twin studies using generalized estimating equations. | Arbet J et al. | β | 2020 | β |
| Breeder friendly phenotyping. | Reynolds M et al. | β | 2020 | β |
| Chromatin dynamics during interphase and cell division: similarities and differences between model and crop plants. | Pecinka A et al. | β | 2020 | β |
| Cognitive ability and education: How behavioural genetic research has advanced our knowledge and understanding of their association. | Malanchini M et al. | β | 2020 | β |
| Comparison of haplotype-based tests for detecting gene-environment interactions with rare variants. | Papachristou C et al. | β | 2020 | β |
| Environment-Wide Association Study (E<sup>n</sup> WAS) of Prenatal and Perinatal Factors Associated With Autistic Traits: A Population-Based Study. | Amiri M et al. | β | 2020 | β |
| From conifers to cognition: Microbes, brain and behavior. | Lathe R et al. | β | 2020 | β |
| Genetic and epigenetic analyses of panic disorder in the post-GWAS era. | Morimoto Y et al. | β | 2020 | β |
| HisCoM-GΓE: Hierarchical Structural Component Analysis of Gene-Based Gene-Environment Interactions. | Choi S et al. | β | 2020 | β |
| How the Science of Reading Informs 21st-Century Education. | Petscher Y et al. | β | 2020 | β |
| Human Pluripotent Stem Cells: A Unique Tool for Toxicity Testing in Pancreatic Progenitor and Endocrine Cells. | MacFarlane EM et al. | β | 2020 | β |
| Identification and genomic analysis of pedigrees with exceptional longevity identifies candidate rare variants. | Miller JB et al. | β | 2020 | β |
| Identification of Disease-Associated Variants by Targeted Gene Panel Resequencing in Parkinson's Disease. | Daida K et al. | β | 2020 | β |
| IgAN Genetic Risk Score in the Clinical Setting. | Schena FP et al. | β | 2020 | β |
| Importance of the environment for gestational duration variability and correlation between relatives - results from the Medical Swedish Birth Registry, 1973-2012. | Modzelewska D et al. | β | 2020 | β |
| Maternal and paternal effects on offspring internalizing problems: Results from genetic and family-based analyses. | Jami ES et al. | β | 2020 | β |
| Missing heritability of complex diseases: case solved? | GΓ©nin E | β | 2020 | β |
| Mitonuclear interactions influence multiple sclerosis risk. | Kozin M et al. | β | 2020 | β |
| Obsessive-compulsive disorder and attention-deficit/hyperactivity disorder: distinct associations with DNA methylation and genetic variation. | Goodman SJ et al. | β | 2020 | β |
| Pan-genomic open reading frames: A potential supplement of single nucleotide polymorphisms in estimation of heritability and genomic prediction. | Li Z et al. | β | 2020 | β |
| Polygenic risk scores: pleiotropy and the effect of environment. | Loika Y et al. | β | 2020 | β |
| Predicting an epistasis-rich genotype-phenotype map with a coarse-grained bottom-up model of budding yeast polarity | Daalman WK et al. | β | 2020 | β |
| Predicting Thermal Adaptation by Looking Into Populations' Genomic Past. | CortΓ©s AJ et al. | β | 2020 | β |
| Proteinarium: Multi-sample protein-protein interaction analysis and visualization tool. | Armanious D et al. | β | 2020 | β |
| Quantitative phenotype scan statistic (QPSS) reveals rare variant associations with Alzheimer's disease endophenotypes. | Katsumata Y et al. | β | 2020 | β |
| Re-evaluating the relationship between missing heritability and the microbiome. | Douglas GM et al. | β | 2020 | β |
| Replicated umbilical cord blood DNA methylation loci associated with gestational age at birth. | York TP et al. | β | 2020 | β |
| The Nubeam reference-free approach to analyze metagenomic sequencing reads. | Dai H et al. | β | 2020 | β |
| 'There and Back Again'-Forward Genetics and Reverse Phenotyping in Pulmonary Arterial Hypertension. | Swietlik EM et al. | β | 2020 | β |
| Use of the Multivariate Discriminant Analysis for Genome-Wide Association Studies in Cattle. | Manca E et al. | β | 2020 | β |
| Utilizing Deep Learning and Genome Wide Association Studies for Epistatic-Driven Preterm Birth Classification in African-American Women. | Fergus P et al. | β | 2020 | β |
| What children and young people learn about ADHD from youth information books: A text analysis of nine books on ADHD available in Dutch. | Batstra L et al. | β | 2020 | β |
| Whole-Genome Approach Discovers Novel Genetic and Nongenetic Variance Components Modulated by Lifestyle for Cardiovascular Health. | Zhou X et al. | β | 2020 | β |
| A genetic variation in the CpG island of pseudogene GBAP1 promoter is associated with gastric cancer susceptibility. | Ma G et al. | β | 2019 | β |
| A genome-wide association and replication study of blood pressure in Ugandan early adolescents. | Lule SA et al. | β | 2019 | β |
| A genome wide association study identifies new genes potentially associated with eyelid sagging. | Laville V et al. | β | 2019 | β |
| An accurate and powerful method for copy number variation detection. | Xiao F et al. | β | 2019 | β |
| Analysis of the genetic basis of height in large Jewish nuclear families. | Zeevi D et al. | β | 2019 | β |
| A permutation method for detecting trend correlations in rare variant association studies. | Liu L et al. | β | 2019 | β |
| A PHLDB1 variant associated with the nonfunctional pituitary adenoma. | Kim LH et al. | β | 2019 | β |
| A regression framework to uncover pleiotropy in large-scale electronic health record data. | Li R et al. | β | 2019 | β |
| Association between <i>PPARG</i> genetic polymorphisms and ischemic stroke risk in a northern Chinese Han population: a case-control study. | Wang YZ et al. | β | 2019 | β |
| A Survey of Copy Number Variation in the Porcine Genome Detected From Whole-Genome Sequence. | Keel BN et al. | β | 2019 | β |
| Best Prediction of the Additive Genomic Variance in Random-Effects Models. | Schreck N et al. | β | 2019 | β |
| Building an Asymmetrical Brain: The Molecular Perspective. | Schmitz J et al. | β | 2019 | β |
| Combination of multi-locus genome-wide association study and QTL mapping reveals genetic basis of tassel architecture in maize. | Wang Y et al. | β | 2019 | β |
| Comparison and assessment of family- and population-based genotype imputation methods in large pedigrees. | Ullah E et al. | β | 2019 | β |
| Comparison of infinitesimal and finite locus models for long-term breeding simulations with direct and maternal effects at the example of honeybees. | Plate M et al. | β | 2019 | β |
| Discovering genetic interactions bridging pathways in genome-wide association studies. | Fang G et al. | β | 2019 | β |
| Early in life effects and heredity: reconciling neo-Darwinism with neo-Lamarckism under the banner of the inclusive evolutionary synthesis. | Danchin Γ et al. | β | 2019 | β |
| Editorial: The Applications of New Multi-Locus GWAS Methodologies in the Genetic Dissection of Complex Traits. | Zhang YM et al. | β | 2019 | β |
| Effects of X-chromosome Tenomodulin Genetic Variants on Obesity in a Children's Cohort and Implications of the Gene in Adipocyte Metabolism. | Ruiz-Ojeda FJ et al. | β | 2019 | β |
| Epigenetic Programming of Adipose Tissue in the Progeny of Obese Dams. | Lecoutre S et al. | β | 2019 | β |
| Epigenome-wide association study in whole blood on type 2 diabetes among sub-Saharan African individuals: findings from the RODAM study. | Meeks KAC et al. | β | 2019 | β |
| Genetic counseling, 2030: An on-demand service tailored to the needs of a price conscious, genetically literate, and busy world. | Rashkin MD et al. | β | 2019 | β |
| Genetics of Atopic Dermatitis: From DNA Sequence to Clinical Relevance. | LΓΈset M et al. | β | 2019 | β |
| Genome-wide analysis of expression quantitative trait loci identified potential lung cancer susceptibility variants among Asian populations. | Fan J et al. | β | 2019 | β |
| Genomic Diversity Evaluation of <i>Populus trichocarpa</i> Germplasm for Rare Variant Genetic Association Studies. | Piot A et al. | β | 2019 | β |
| Haplotype and Haplotype-Environment Interaction Analysis Revealed Roles of SPRY2 for NSCL/P among Chinese Populations. | Zhou R et al. | β | 2019 | β |
| Heritability estimation of dichotomous phenotypes using a liability threshold model on ascertained family-based samples. | Kim W et al. | β | 2019 | β |
| HLA-C: An Accomplice in Rheumatic Diseases. | Siegel RJ et al. | β | 2019 | β |
| How to approach understanding complex trait genetics - inflammatory bowel disease as a model complex trait. | Cleynen I et al. | β | 2019 | β |
| Innovative strategies for annotating the "relationSNP" between variants and molecular phenotypes. | Miller JE et al. | β | 2019 | β |
| Inter- and intra-breed genome-wide copy number diversity in a large cohort of European equine breeds. | SolΓ© M et al. | β | 2019 | β |
| Lessons Learned From GWAS of Asthma. | Kim KW et al. | β | 2019 | β |
| Machine Learning Methods as a Tool for Predicting Risk of Illness Applying Next-Generation Sequencing Data. | Njage PMK et al. | β | 2019 | β |
| Nucleotide Identification in DNA Using Dielectrophoresis Spectroscopy. | Gudagunti FD et al. | β | 2019 | β |
| Optimising the identification of causal variants across varying genetic architectures in crops. | Miao C et al. | β | 2019 | β |
| Pathway analysis of rare variants for the clustered phenotypes by using hierarchical structured components analysis. | Lee S et al. | β | 2019 | β |
| Primers on nutrigenetics and nutri(epi)genomics: Origins and development of precision nutrition. | Bordoni L et al. | β | 2019 | β |
| Rare copy number variation in extremely impulsively violent males. | Vevera J et al. | β | 2019 | β |
| Rare missense variants in the human cytosolic antibody receptor preserve antiviral function. | Zeng J et al. | β | 2019 | β |
| Realized Genome Sharing in Heritability Estimation Using Random Effects Models. | Wang B et al. | β | 2019 | β |
| Reliable heritability estimation using sparse regularization in ultrahigh dimensional genome-wide association studies. | Li X et al. | β | 2019 | β |
| Tackling Missing Heritability by Use of an Optimum Curve: A Systematic Review and Meta-Analysis. | Wegener Sleeswijk A et al. | β | 2019 | β |
| The endocytic membrane trafficking pathway plays a major role in the risk of Parkinson's disease. | Bandres-Ciga S et al. | β | 2019 | β |
| Toxoplasmosis: A pathway to neuropsychiatric disorders. | Tyebji S et al. | β | 2019 | β |
| Transgenerational epigenetic influences of paternal environmental exposures on brain function and predisposition to psychiatric disorders. | Yeshurun S et al. | β | 2019 | β |
| Uncovering Missing Heritability in Rare Diseases. | Maroilley T et al. | β | 2019 | β |
| A Family-Based Rare Haplotype Association Method for Quantitative Traits. | Datta AS et al. | β | 2018 | β |
| A large electronic-health-record-based genome-wide study of serum lipids. | Hoffmann TJ et al. | β | 2018 | β |
| A rare missense variant in RCL1 segregates with depression in extended families. | Amin N et al. | β | 2018 | β |
| A Review on Methods for Detecting SNP Interactions in High-Dimensional Genomic Data. | Uppu S et al. | β | 2018 | β |
| Association analysis of multiple traits by an approach of combining P values. | Chen L et al. | β | 2018 | β |
| Association between Vitamin D Genetic Risk Score and Cancer Risk in a Large Cohort of U.S. Women. | Chandler PD et al. | β | 2018 | β |
| Can Deep Learning Improve Genomic Prediction of Complex Human Traits? | Bellot P et al. | β | 2018 | β |
| Causality and complex disease: The example of multiple sclerosis. | Bach JF | β | 2018 | β |
| ClusterMI: Detecting High-Order SNP Interactions Based on Clustering and Mutual Information. | Cao X et al. | β | 2018 | β |
| Collective feature selection to identify crucial epistatic variants. | Verma SS et al. | β | 2018 | β |
| Complex-Trait Prediction in the Era of Big Data. | de Los Campos G et al. | β | 2018 | β |
| Effect of migration and environmental heterogeneity on the maintenance of quantitative genetic variation: a simulation study. | McDonald TK et al. | β | 2018 | β |
| Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees. | Jun G et al. | β | 2018 | β |
| Four Parent Maize (FPM) Population: Effects of Mating Designs on Linkage Disequilibrium and Mapping Quantitative Traits. | Anderson SL et al. | β | 2018 | β |
| Genetic and environmental contributions to psychological resilience and coping. | Navrady LB et al. | β | 2018 | β |
| Genetic and Environmental Contributions to the Covariation Between Cardiometabolic Traits. | Chen X et al. | β | 2018 | β |
| Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population. | Li Y et al. | β | 2018 | β |
| Genotyping by Sequencing and Genome-Environment Associations in Wild Common Bean Predict Widespread Divergent Adaptation to Drought. | CortΓ©s AJ et al. | β | 2018 | β |
| Health, wealth and behavioural change: an exploration of role responsibilities in the wake of epigenetics. | Vears DF et al. | β | 2018 | β |
| How powerful are summary-based methods for identifying expression-trait associations under different genetic architectures? | Veturi Y et al. | β | 2018 | β |
| Improved estimation of SNP heritability using Bayesian multiple-phenotype models. | Elhezzani NS | β | 2018 | β |
| Informatics and machine learning to define the phenotype. | Basile AO et al. | β | 2018 | β |
| Kernel machine methods for integrative analysis of genome-wide methylation and genotyping studies. | Zhao N et al. | β | 2018 | β |
| Learning the optimal scale for GWAS through hierarchical SNP aggregation. | Guinot F et al. | β | 2018 | β |
| Loss of LDAH associated with prostate cancer and hearing loss. | Currall BB et al. | β | 2018 | β |
| Machine Learning and Radiogenomics: Lessons Learned and Future Directions. | Kang J et al. | β | 2018 | β |
| Maternal obesity, diabetes during pregnancy and epigenetic mechanisms that influence the developmental origins of cardiometabolic disease in the offspring. | Agarwal P et al. | β | 2018 | β |
| Metastable DNA methylation sites associated with longitudinal lung function decline and aging in humans: an epigenome-wide study in the NAS and KORA cohorts. | Carmona JJ et al. | β | 2018 | β |
| Methods for Polygenic Traits. | Pazoki R | β | 2018 | β |
| Multi-Environmental Trials Reveal Genetic Plasticity of Oat Agronomic Traits Associated With Climate Variable Changes. | Rispail N et al. | β | 2018 | β |
| Novel pedigree analysis implicates DNA repair and chromatin remodeling in multiple myeloma risk. | Waller RG et al. | β | 2018 | β |
| One Hundred Years of Linkage Disequilibrium. | Sved JA et al. | β | 2018 | β |
| On the Causes of Rapid Diversification in the PΓ‘ramos: Isolation by Ecology and Genomic Divergence in <i>Espeletia</i>. | CortΓ©s AJ et al. | β | 2018 | β |
| Performance of epistasis detection methods in semi-simulated GWAS. | Chatelain C et al. | β | 2018 | β |
| Pipeline design to identify key features and classify the chemotherapy response on lung cancer patients using large-scale genetic data. | ValdΓ©s MG et al. | β | 2018 | β |
| Power comparison of Cochran-Armitage trend test against allelic and genotypic tests in large-scale case-control genetic association studies. | Emily M | β | 2018 | β |
| Precision pharmacotherapy: psychiatry's future direction in preventing, diagnosing, and treating mental disorders. | Menke A | β | 2018 | β |
| Replicability and Prediction: Lessons and Challenges from GWAS. | Marigorta UM et al. | β | 2018 | β |
| Sepsis: Personalized Medicine Utilizing 'Omic' Technologies-A Paradigm Shift? | Itenov TS et al. | β | 2018 | β |
| SMMB: a stochastic Markov blanket framework strategy for epistasis detection in GWAS. | Niel C et al. | β | 2018 | β |
| Spontaneous preterm birth: advances toward the discovery of genetic predisposition. | Strauss JF et al. | β | 2018 | β |
| Statistical Analysis of Multiple Phenotypes in Genetic Epidemiologic Studies: From Cross-Phenotype Associations to Pleiotropy. | Salinas YD et al. | β | 2018 | β |
| Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. | Kulminski AM et al. | β | 2018 | β |
| Studying microbial functionality within the gut ecosystem by systems biology. | Hornung B et al. | β | 2018 | β |
| The Microbiological Memory, an Epigenetic Regulator Governing the Balance Between Good Health and Metabolic Disorders. | Devaux CA et al. | β | 2018 | β |
| The search for gene-gene interactions in genome-wide association studies: challenges in abundance of methods, practical considerations, and biological interpretation. | Ritchie MD et al. | β | 2018 | β |
| Visual motion and rapid auditory processing are solid endophenotypes of developmental dyslexia. | Mascheretti S et al. | β | 2018 | β |
| WISARD: workbench for integrated superfast association studies for related datasets. | Lee S et al. | β | 2018 | β |
| 10 Years of GWAS Discovery: Biology, Function, and Translation. | Visscher PM et al. | β | 2017 | β |
| Academic textbooks [corrected] on ADHD genetics: balanced or biased? | Te Meerman S et al. | β | 2017 | β |
| A Comparison of Heritability Estimates by Classical Twin Modeling and Based on Genome-Wide Genetic Relatedness for Cardiac Conduction Traits. | Nolte IM et al. | β | 2017 | β |
| A decade of progress on the genetic basis of coronary artery disease. Practical insights for the internist. | Girelli D et al. | β | 2017 | β |
| An adaptive strategy for association analysis of common or rare variants using entropy theory. | Li YM et al. | β | 2017 | β |
| Analysis of Gene-Gene Interactions. | Cole BS et al. | β | 2017 | β |
| An integrative review of methylation at the serotonin transporter gene and its dialogue with environmental risk factors, psychopathology and 5-HTTLPR. | Palma-Gudiel H et al. | β | 2017 | β |
| A Novel QTL for Powdery Mildew Resistance in Nordic Spring Barley (<i>Hordeum vulgare</i> L. ssp. <i>vulgare</i>) Revealed by Genome-Wide Association Study. | Bengtsson T et al. | β | 2017 | β |
| Antagonistic genetic correlations for milking traits within the genome of dairy cattle. | Gervais O et al. | β | 2017 | β |
| A Review of the Genetics of Hypertension with a Focus on Gene-Environment Interactions. | Waken RJ et al. | β | 2017 | β |
| Assessing Relevance of External Cognitive Measures. | CairΓ³ O | β | 2017 | β |
| Beyond the genome-Towards an epigenetic understanding of handedness ontogenesis. | Schmitz J et al. | β | 2017 | β |
| Causality and complex disease: The example of multiple sclerosis. | Bach JF | β | 2017 | β |
| Chronic rhinosinusitis in Asia. | Zhang Y et al. | β | 2017 | β |
| Comparative genome-wide methylation analysis of longissimus dorsi muscles between Japanese black (Wagyu) and Chinese Red Steppes cattle. | Fang X et al. | β | 2017 | β |
| Complex effects of dyslexia risk factors account for ADHD traits: evidence from two independent samples. | Mascheretti S et al. | β | 2017 | β |
| Concepts, estimation and interpretation of SNP-based heritability. | Yang J et al. | β | 2017 | β |
| Contribution of rare and low-frequency whole-genome sequence variants to complex traits variation in dairy cattle. | Zhang Q et al. | β | 2017 | β |
| Detecting disease association with rare variants in case-parents studies. | Li YM et al. | β | 2017 | β |
| Detecting genetic association through shortest paths in a bidirected graph. | Ueki M et al. | β | 2017 | β |
| Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals. | Holzinger ER et al. | β | 2017 | β |
| Disease-Concordant Twins Empower Genetic Association Studies. | Tan Q et al. | β | 2017 | β |
| DNA methylation mediates genotype and smoking interaction in the development of anti-citrullinated peptide antibody-positive rheumatoid arthritis. | Meng W et al. | β | 2017 | β |
| DoEstRare: A statistical test to identify local enrichments in rare genomic variants associated with disease. | Persyn E et al. | β | 2017 | β |
| Endocrinology Meets Metabolomics: Achievements, Pitfalls, and Challenges. | Tokarz J et al. | β | 2017 | β |
| Epigenetic Mechanisms of Transmission of Metabolic Disease across Generations. | Sales VM et al. | β | 2017 | β |
| Epigenetics for Plant Improvement: Current Knowledge and Modeling Avenues. | Gallusci P et al. | β | 2017 | β |
| Estimation of heritability for nine common cancers using data from genome-wide association studies in Chinese population. | Dai J et al. | β | 2017 | β |
| Exploring and Harnessing Haplotype Diversity to Improve Yield Stability in Crops. | Qian L et al. | β | 2017 | β |
| Future Directions of Genomics Research in Rheumatic Diseases. | Okada Y et al. | β | 2017 | β |
| Gene-nutrient interactions and susceptibility to human obesity. | Castillo JJ et al. | β | 2017 | β |
| Genetic factors associated with risk of metabolic syndrome and hepatocellular carcinoma. | Tang R et al. | β | 2017 | β |
| Genetics and educational attainment. | Cesarini D et al. | β | 2017 | β |
| Genome-Wide Association Mapping of Flowering and Ripening Periods in Apple. | Urrestarazu J et al. | β | 2017 | β |
| Genome-wide Association Studies in Maize: Praise and Stargaze. | Xiao Y et al. | β | 2017 | β |
| Genome-wide estimation of heritability and its functional components for flowering, defense, ionomics, and developmental traits in a geographically diverse population of Arabidopsis thaliana. | Yang RC | β | 2017 | β |
| Genome-wide identification of inter-individually variable DNA methylation sites improves the efficacy of epigenetic association studies. | Hachiya T et al. | β | 2017 | β |
| graph-GPA: A graphical model for prioritizing GWAS results and investigating pleiotropic architecture. | Chung D et al. | β | 2017 | β |
| Heritability Estimation using a Regularized Regression Approach (HERRA): Applicable to continuous, dichotomous or age-at-onset outcome. | Gorfine M et al. | β | 2017 | β |
| Histone Modifications in Major Depressive Disorder and Related Rodent Models. | Deussing JM et al. | β | 2017 | β |
| Imaging genetics in attention-deficit/hyperactivity disorder and related neurodevelopmental domains: state of the art. | Vilor-Tejedor N et al. | β | 2017 | β |
| Incorporation of Biological Knowledge Into the Study of Gene-Environment Interactions. | Ritchie MD et al. | β | 2017 | β |
| Invited review: A perspective on the future of genomic selection in dairy cattle. | Weller JI et al. | β | 2017 | β |
| Locally epistatic models for genome-wide prediction and association by importance sampling. | Akdemir D et al. | β | 2017 | β |
| Meta-GWAS Accuracy and Power (MetaGAP) Calculator Shows that Hiding Heritability Is Partially Due to Imperfect Genetic Correlations across Studies. | de Vlaming R et al. | β | 2017 | β |
| Multiple rare genetic variants co-segregating with familial IgA nephropathy all act within a single immune-related network. | Cox SN et al. | β | 2017 | β |
| Neurogenetics of developmental dyslexia: from genes to behavior through brain neuroimaging and cognitive and sensorial mechanisms. | Mascheretti S et al. | β | 2017 | β |
| Next-generation metabolomics in lung cancer diagnosis, treatment and precision medicine: mini review. | Yu L et al. | β | 2017 | β |
| Pathway-based discovery of genetic interactions in breast cancer. | Wang W et al. | β | 2017 | β |
| QT Interval Determinant: Mutations, Rare Variants, or Single-Nucleotide Polymorphisms? | Aiba T et al. | β | 2017 | β |
| Reevaluation of SNP heritability in complex human traits. | Speed D et al. | β | 2017 | β |
| Selecting cases and controls for DNA sequencing studies using family histories of disease. | Kim W et al. | β | 2017 | β |
| The role of READ1 and KIAA0319 genetic variations in developmental dyslexia: testing main and interactive effects. | Trezzi V et al. | β | 2017 | β |
| What can time-frequency and phase coherence measures tell us about the genetic basis of P3 amplitude? | Malone SM et al. | β | 2017 | β |
| What has GWAS done for HLA and disease associations? | Kennedy AE et al. | β | 2017 | β |
| What have humans done for evolutionary biology? Contributions from genes to populations. | Briga M et al. | β | 2017 | β |
| Why the missing heritability might not be in the DNA. | Bourrat P et al. | β | 2017 | β |
| Will Big Data Close the Missing Heritability Gap? | Kim H et al. | β | 2017 | β |
| Accuracy of heritability estimations in presence of hidden population stratification. | Dandine-Roulland C et al. | β | 2016 | β |
| A Comparative Study of Five Association Tests Based on CpG Set for Epigenome-Wide Association Studies. | Zhang Q et al. | β | 2016 | β |
| A Dormant Microbial Component in the Development of Preeclampsia. | Kell DB et al. | β | 2016 | β |
| A genome-wide association study for genetic susceptibility to Mycobacterium bovis infection in dairy cattle identifies a susceptibility QTL on chromosome 23. | Richardson IW et al. | β | 2016 | β |
| A nonparametric method to test for associations between rare variants and multiple traits. | Zhou Y et al. | β | 2016 | β |
| Applications and limitations in translating genomics to clinical practice. | Van Ness B | β | 2016 | β |
| Association of polymorphisms in the aldosterone-regulated sodium reabsorption pathway with blood pressure among Hispanics. | Tayo BO et al. | β | 2016 | β |
| AstRoMap European Astrobiology Roadmap. | Horneck G et al. | β | 2016 | β |
| Attentional biases to emotional stimuli: Key components of the RDoC constructs of sustained threat and loss. | Gibb BE et al. | β | 2016 | β |
| Block-based association tests for rare variants using Kullback-Leibler divergence. | Zhu D et al. | β | 2016 | β |
| CINOEDV: a co-information based method for detecting and visualizing n-order epistatic interactions. | Shang J et al. | β | 2016 | β |
| Comparison of gene-based rare variant association mapping methods for quantitative traits in a bovine population with complex familial relationships. | Zhang Q et al. | β | 2016 | β |
| Comparison of haplotype-based statistical tests for disease association with rare and common variants. | Datta AS et al. | β | 2016 | β |
| Complex genetics of pulmonary diseases: lessons from genome-wide association studies and next-generation sequencing. | Pouladi N et al. | β | 2016 | β |
| Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis. | Sieberts SK et al. | β | 2016 | β |
| Detecting Gene-Environment Interactions for a Quantitative Trait in a Genome-Wide Association Study. | Zhang P et al. | β | 2016 | β |
| Detecting Gene-Gene Interactions Associated with Multiple Complex Traits with U-Statistics. | Li M et al. | β | 2016 | β |
| Detecting the Common and Individual Effects of Rare Variants on Quantitative Traits by Using Extreme Phenotype Sampling. | Zhou YJ et al. | β | 2016 | β |
| Detecting the QTL-allele system of seed isoflavone content in Chinese soybean landrace population for optimal cross design and gene system exploration. | Meng S et al. | β | 2016 | β |
| Developmental Origins of Common Disease: Epigenetic Contributions to Obesity. | Kappil M et al. | β | 2016 | β |
| Discovering causal interactions using Bayesian network scoring and information gain. | Zeng Z et al. | β | 2016 | β |
| Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures. | Wang X et al. | β | 2016 | β |
| Embracing Complex Associations in Common Traits: Critical Considerations for Precision Medicine. | Hall MA et al. | β | 2016 | β |
| Emerging applications of metabolomics in drug discovery and precision medicine. | Wishart DS | β | 2016 | β |
| Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium. | Verma SS et al. | β | 2016 | β |
| Evaluation of polygenic risks for narcolepsy and essential hypersomnia. | Yamasaki M et al. | β | 2016 | β |
| Evidence for Increased 5Ξ±-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome. | Torchen LC et al. | β | 2016 | β |
| Evidence from pyrosequencing indicates that natural variation in animal personality is associated with DRD4 DNA methylation. | Verhulst EC et al. | β | 2016 | β |
| Exploring the Genetic Patterns of Complex Diseases via the Integrative Genome-Wide Approach. | Teng B et al. | β | 2016 | β |
| FARVATX: Family-Based Rare Variant Association Test for X-Linked Genes. | Choi S et al. | β | 2016 | β |
| Feature co-localization landscape of the human genome. | Ng SK et al. | β | 2016 | β |
| From genetic associations to functional studies in multiple sclerosis. | Bos SD et al. | β | 2016 | β |
| Gene expression profiling analysis contributes to understanding the association between non-syndromic cleft lip and palate, and cancer. | Wang H et al. | β | 2016 | β |
| Gene-gene Interaction Analyses for Atrial Fibrillation. | Lin H et al. | β | 2016 | β |
| Genetics of Insulin Resistance and the Metabolic Syndrome. | Brown AE et al. | β | 2016 | β |
| Genetics of leprosy: Expected-and unexpected-developments and perspectives. | Sauer ME et al. | β | 2016 | β |
| Genetic variation in IBD: progress, clues to pathogenesis and possible clinical utility. | Ye BD et al. | β | 2016 | β |
| Genome-wide association studies of drought-related metabolic changes in maize using an enlarged SNP panel. | Zhang X et al. | β | 2016 | β |
| Genome-Wide Association Studies with a Genomic Relationship Matrix: A Case Study with Wheat and Arabidopsis. | Gianola D et al. | β | 2016 | β |
| Genomic sequencing in clinical practice: applications, challenges, and opportunities. | Krier JB et al. | β | 2016 | β |
| Guide and Position of the International Society of Nutrigenetics/Nutrigenomics on Personalised Nutrition: Part 1 - Fields of Precision Nutrition. | Ferguson LR et al. | β | 2016 | β |
| Identification of genetic interaction networks via an evolutionary algorithm evolved Bayesian network. | Li R et al. | β | 2016 | β |
| Incorporating Non-Coding Annotations into Rare Variant Analysis. | Richardson TG et al. | β | 2016 | β |
| Irf6 directly regulates Klf17 in zebrafish periderm and Klf4 in murine oral epithelium, and dominant-negative KLF4 variants are present in patients with cleft lip and palate. | Liu H et al. | β | 2016 | β |
| KNOWLEDGE DRIVEN BINNING AND PHEWAS ANALYSIS IN MARSHFIELD PERSONALIZED MEDICINE RESEARCH PROJECT USING BIOBIN. | Basile AO et al. | β | 2016 | β |
| LAMPLINK: detection of statistically significant SNP combinations from GWAS data. | Terada A et al. | β | 2016 | β |
| Limitations of GCTA as a solution to the missing heritability problem. | Krishna Kumar S et al. | β | 2016 | β |
| Low attentive and high impulsive rats: A translational animal model of ADHD and disorders of attention and impulse control. | Hayward A et al. | β | 2016 | β |
| Meta-dimensional data integration identifies critical pathways for susceptibility, tumorigenesis and progression of endometrial cancer. | Wei R et al. | β | 2016 | β |
| Mirror, mirror on the wall: which microbiomes will help heal them all? | Nayak RR et al. | β | 2016 | β |
| Missing heritability of complex diseases: Enlightenment by genetic variants from intermediate phenotypes. | Blanco-GΓ³mez A et al. | β | 2016 | β |
| Non-linear interactions between candidate genes of myocardial infarction revealed in mRNA expression profiles. | Hartmann K et al. | β | 2016 | β |
| On the Accuracy of Genomic Selection. | Rabier CE et al. | β | 2016 | β |
| Pathway-based approach using hierarchical components of collapsed rare variants. | Lee S et al. | β | 2016 | β |
| PHENOME-WIDE INTERACTION STUDY (PheWIS) IN AIDS CLINICAL TRIALS GROUP DATA (ACTG). | Verma SS et al. | β | 2016 | β |
| Phenotypic Evolution With and Beyond Genome Evolution. | FΓ©lix MA | β | 2016 | β |
| Polygenic Epidemiology. | Dudbridge F | β | 2016 | β |
| Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans. | Olfson E et al. | β | 2016 | β |
| Rare Variants Association Analysis in Large-Scale Sequencing Studies at the Single Locus Level. | Jeng XJ et al. | β | 2016 | β |
| RDoC and translational perspectives on the genetics of trauma-related psychiatric disorders. | Montalvo-Ortiz JL et al. | β | 2016 | β |
| Reconciling evidence-based medicine and precision medicine in the era of big data: challenges and opportunities. | Beckmann JS et al. | β | 2016 | β |
| Revisiting Human Cholesterol Synthesis and Absorption: The Reciprocity Paradigm and its Key Regulators. | Alphonse PA et al. | β | 2016 | β |
| Single nucleotide polymorphisms in clinics: Fantasy or reality for cancer? | Srinivasan S et al. | β | 2016 | β |
| Strong genetic overlap between executive functions and intelligence. | Engelhardt LE et al. | β | 2016 | β |
| Systems Medicine: hype or revolution? | FleΓa S et al. | β | 2016 | β |
| The search for modifier genes in Huntington disease - Multifactorial aspects of a monogenic disorder. | Arning L | β | 2016 | β |
| Accurate Imputation-Based Screening of Gln368Ter Myocilin Variant in Primary Open-Angle Glaucoma. | Gharahkhani P et al. | β | 2015 | β |
| A critical assessment of the equal-environment assumption of the twin method for schizophrenia. | Fosse R et al. | β | 2015 | β |
| Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families. | Park S et al. | β | 2015 | β |
| Aetiological coding sequence variants in non-syndromic premature ovarian failure: From genetic linkage analysis to next generation sequencing. | Laissue P | β | 2015 | β |
| A Fast Method that Uses Polygenic Scores to Estimate the Variance Explained by Genome-wide Marker Panels and the Proportion of Variants Affecting a Trait. | Palla L et al. | β | 2015 | β |
| affy2sv: an R package to pre-process Affymetrix CytoScan HD and 750K arrays for SNP, CNV, inversion and mosaicism calling. | Hernandez-Ferrer C et al. | β | 2015 | β |
| A gene-based information gain method for detecting gene-gene interactions in case-control studies. | Li J et al. | β | 2015 | β |
| A GWAS assessment of the contribution of genomic imprinting to the variation of body mass index in mice. | Hu Y et al. | β | 2015 | β |
| Allele-specific imbalance mapping at human orthologs of mouse susceptibility to colon cancer (Scc) loci. | Gerber MM et al. | β | 2015 | β |
| A meta-analysis of heritability of cognitive aging: minding the "missing heritability" gap. | Reynolds CA et al. | β | 2015 | β |
| A Multi-Marker Genetic Association Test Based on the Rasch Model Applied to Alzheimer's Disease. | Wang W et al. | β | 2015 | β |
| An assessment of gene-by-gene interactions as a tool to unfold missing heritability in dyslexia. | Mascheretti S et al. | β | 2015 | β |
| An Improved Opposition-Based Learning Particle Swarm Optimization for the Detection of SNP-SNP Interactions. | Shang J et al. | β | 2015 | β |
| An Improved Version of Logistic Bayesian LASSO for Detecting Rare Haplotype-Environment Interactions with Application to Lung Cancer. | Zhang Y et al. | β | 2015 | β |
| An overview of SNP interactions in genome-wide association studies. | Li P et al. | β | 2015 | β |
| A robust distribution-free test for genetic association studies of quantitative traits. | Kozlitina J et al. | β | 2015 | β |
| A robust GWSS method to simultaneously detect rare and common variants for complex disease. | Kao CF et al. | β | 2015 | β |
| Assessing the Power of Exome Chips. | Page CM et al. | β | 2015 | β |
| Assessment of whole-genome regression for type II diabetes. | Vazquez AI et al. | β | 2015 | β |
| Association between cannabinoid receptor type 2 Q63R variant and oligo/polyarticular juvenile idiopathic arthritis. | Bellini G et al. | β | 2015 | β |
| Association mapping in Populus reveals the interaction between Pto-miR530a and its target Pto-KNAT1. | Yang X et al. | β | 2015 | β |
| A survey about methods dedicated to epistasis detection. | Niel C et al. | β | 2015 | β |
| ATG18 and FAB1 are involved in dehydration stress tolerance in Saccharomyces cerevisiae. | LΓ³pez-MartΓnez G et al. | β | 2015 | β |
| Biological knowledge-driven analysis of epistasis in human GWAS with application to lipid traits. | Ma L et al. | β | 2015 | β |
| Biology-Driven Gene-Gene Interaction Analysis of Age-Related Cataract in the eMERGE Network. | Hall MA et al. | β | 2015 | β |
| Body size, physical activity, genetic variants in the insulin-like growth factor pathway and colorectal cancer risk. | Simons CC et al. | β | 2015 | β |
| Constitutional epimutation as a mechanism for cancer causality and heritability? | Hitchins MP | β | 2015 | β |
| Copy number variations play important roles in heredity of common diseases: a novel method to calculate heritability of a polymorphism. | Nagao Y | β | 2015 | β |
| Dearth of polymorphism associated with a sustained response to selection for flowering time in maize. | Durand E et al. | β | 2015 | β |
| Detecting association of rare and common variants by adaptive combination of P-values. | Zhou Y et al. | β | 2015 | β |
| Developmental psychopathology in an era of molecular genetics and neuroimaging: A developmental neurogenetics approach. | Hyde LW | β | 2015 | β |
| Dietary Patterns, Genes, and Health: Challenges and Obstacles to be Overcome. | Frazier-Wood AC | β | 2015 | β |
| Direct Estimates of the Genomic Contributions to Blood Pressure Heritability within a Population-Based Cohort (ARIC). | Salfati E et al. | β | 2015 | β |
| Dominance genetic variation contributes little to the missing heritability for human complex traits. | Zhu Z et al. | β | 2015 | β |
| Dominant Genetic Variation and Missing Heritability for Human Complex Traits: Insights from Twin versus Genome-wide Common SNP Models. | Chen X et al. | β | 2015 | β |
| Early life origins of metabolic disease: Developmental programming of hypothalamic pathways controlling energy homeostasis. | Dearden L et al. | β | 2015 | β |
| Early life trauma, depression and the glucocorticoid receptor gene--an epigenetic perspective. | Smart C et al. | β | 2015 | β |
| Effectiveness of shrinkage and variable selection methods for the prediction of complex human traits using data from distantly related individuals. | Berger S et al. | β | 2015 | β |
| Effect of occupational exposures on lung cancer susceptibility: a study of gene-environment interaction analysis. | Malhotra J et al. | β | 2015 | β |
| Enrichment of Minor Alleles of Common SNPs and Improved Risk Prediction for Parkinson's Disease. | Zhu Z et al. | β | 2015 | β |
| Estimation of Additive, Dominance, and Imprinting Genetic Variance Using Genomic Data. | Lopes MS et al. | β | 2015 | β |
| Evaluation of a two-stage framework for prediction using big genomic data. | Jiang X et al. | β | 2015 | β |
| Evolving concepts of heredity and genetics in orthodontics. | Carlson DS | β | 2015 | β |
| Exome and whole genome sequencing in aging and longevity. | van den Akker EB et al. | β | 2015 | β |
| Eyes on the price: Human culture and its teaching. | MΓΌller CP | β | 2015 | β |
| Family-based association analysis: a fast and efficient method of multivariate association analysis with multiple variants. | Won S et al. | β | 2015 | β |
| Family-Based Benchmarking of Copy Number Variation Detection Software. | Nutsua ME et al. | β | 2015 | β |
| Finding the epistasis needles in the genome-wide haystack. | Ritchie MD | β | 2015 | β |
| From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition? | Szarc vel Szic K et al. | β | 2015 | β |
| Functional outcome in major psychiatric disorders and associated clinical and psychosocial variables: A potential cross-diagnostic phenotype for further genetic investigations? | Gade K et al. | β | 2015 | β |
| Genetic diagnosis and prognosis of Alzheimer's disease: challenges and opportunities. | Reitz C | β | 2015 | β |
| Genetics and brain morphology. | Strike LT et al. | β | 2015 | β |
| Genetics of leprosy: expected and unexpected developments and perspectives. | Sauer ME et al. | β | 2015 | β |
| Genetics of non-conventional lipoprotein fractions. | Frazier-Wood AC | β | 2015 | β |
| Genetic variants in the inositol phosphate metabolism pathway and risk of different types of cancer. | Tan J et al. | β | 2015 | β |
| Genetic Variants in the Insulin-like Growth Factor Pathway and Colorectal Cancer Risk in the Netherlands Cohort Study. | Simons CC et al. | β | 2015 | β |
| Genome-wide association for heifer reproduction and calf performance traits in beef cattle. | Akanno EC et al. | β | 2015 | β |
| Genome-wide association study of reproductive traits in Nellore heifers using Bayesian inference. | Costa RB et al. | β | 2015 | β |
| Genomic prediction of seedling root length in maize (Zea mays L.). | Pace J et al. | β | 2015 | β |
| GWAS and Meta-Analysis in Aging/Longevity. | Broer L et al. | β | 2015 | β |
| HaploShare: identification of extended haplotypes shared by cases and evaluation against controls. | Ying D et al. | β | 2015 | β |
| Heritability Estimated Using 50K SNPs Indicates Missing Heritability Problem in Holstein Breeding. | Shin D et al. | β | 2015 | β |
| Heritability of liver enzyme levels estimated from genome-wide SNP data. | van Beek JH et al. | β | 2015 | β |
| Identification of Genes Whose Expression Profile Is Associated with Non-Progression towards AIDS Using eQTLs. | Spadoni JL et al. | β | 2015 | β |
| Impact of QTL minor allele frequency on genomic evaluation using real genotype data and simulated phenotypes in Japanese Black cattle. | Uemoto Y et al. | β | 2015 | β |
| Insatiable insecurity: maternal obesity as a risk factor for mother-child attachment and child weight. | Keitel-KorndΓΆrfer A et al. | β | 2015 | β |
| Integrating Crop Growth Models with Whole Genome Prediction through Approximate Bayesian Computation. | Technow F et al. | β | 2015 | β |
| Interaction association analysis of imputed SNPs in case-control and follow-up studies. | Subirana I et al. | β | 2015 | β |
| Kullback-Leibler distance methods for detecting disease association with rare variants from sequencing data. | Turkmen AS et al. | β | 2015 | β |
| LEAP: biomarker inference through learning and evaluating association patterns. | Jiang X et al. | β | 2015 | β |
| Learning Predictive Interactions Using Information Gain and Bayesian Network Scoring. | Jiang X et al. | β | 2015 | β |
| Mendelian genes for Parkinson's disease contribute to the sporadic forms of the disease. | Spataro N et al. | β | 2015 | β |
| Meta-analysis of the heritability of human traits based on fifty years of twin studies. | Polderman TJ et al. | β | 2015 | β |
| MicroRNAs enrichment in GWAS of complex human phenotypes. | Goulart LF et al. | β | 2015 | β |
| Mutations Causing Complex Disease May under Certain Circumstances Be Protective in an Epidemiological Sense. | Siegert S et al. | β | 2015 | β |
| Natural history of Ξ²-cell adaptation and failure in type 2 diabetes. | Alejandro EU et al. | β | 2015 | β |
| New developments in the genetics, pathogenesis, and therapy of IgA nephropathy. | Magistroni R et al. | β | 2015 | β |
| Parallelizing Epistasis Detection in GWAS on FPGA and GPU-Accelerated Computing Systems. | GonzΓ‘lez-DomΓnguez J et al. | β | 2015 | β |
| Paramutation in evolution, population genetics and breeding. | Springer NM et al. | β | 2015 | β |
| Pathway-Based Genome-Wide Association Studies for Plasma Triglycerides in Obese Females and Normal-Weight Controls. | Jiao H et al. | β | 2015 | β |
| Performance of genotype imputation for low frequency and rare variants from the 1000 genomes. | Zheng HF et al. | β | 2015 | β |
| Phenome-Wide Association Studies: Embracing Complexity for Discovery. | Pendergrass SA et al. | β | 2015 | β |
| Polygenic Scores in Epidemiology: Risk Prediction, Etiology, and Clinical Utility. | Maher BS | β | 2015 | β |
| Prediction of complex human diseases from pathway-focused candidate markers by joint estimation of marker effects: case of chronic fatigue syndrome. | Bhattacharjee M et al. | β | 2015 | β |
| Rapid analysis of colipase gene variants by multicapillary electrophoresis. | JaczΓ³ Z et al. | β | 2015 | β |
| Rethinking inheritance, yet again: inheritomes, contextomes and dynamic phenotypes. | Prasad NG et al. | β | 2015 | β |
| Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. | Soler Artigas M et al. | β | 2015 | β |
| Statistical analysis for genome-wide association study. | Zeng P et al. | β | 2015 | β |
| Stratified medicine for the use of antidiabetic medication in treatment of type II diabetes and cancer: where do we go from here? | Emami-Riedmaier A et al. | β | 2015 | β |
| Study Designs for Exploring the Non-HLA Genetics in Celiac Disease. | Naluai Γ T | β | 2015 | β |
| Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently. | Currin A et al. | β | 2015 | β |
| The Association between HMGA1 rs146052672 Variant and Type 2 Diabetes: A Transethnic Meta-Analysis. | Bianco A et al. | β | 2015 | β |
| The Biodemography of Fertility: A Review and Future Research Frontiers. | Mills MC et al. | β | 2015 | β |
| The cancer cell map initiative: defining the hallmark networks of cancer. | Krogan NJ et al. | β | 2015 | β |
| The contribution of genomic research to explaining racial disparities in cardiovascular disease: a systematic review. | Kaufman JS et al. | β | 2015 | β |
| The genetic architecture of autism spectrum disorders (ASDs) and the potential importance of common regulatory genetic variants. | Saffen D | β | 2015 | β |
| The molecular genetic architecture of attention deficit hyperactivity disorder. | Hawi Z et al. | β | 2015 | β |
| The Nature of Genetic Variation for Complex Traits Revealed by GWAS and Regional Heritability Mapping Analyses. | Caballero A et al. | β | 2015 | β |
| The unforeseen challenge: from genotype-to-phenotype in cell populations. | Braun E | β | 2015 | β |
| The uniform-score gene set analysis for identifying common pathways associated with different diabetes traits. | Mei H et al. | β | 2015 | β |
| Understanding inflammatory bowel disease via immunogenetics. | de Lange KM et al. | β | 2015 | β |
| A case-control design for testing and estimating epigenetic effects on complex diseases. | Sui Y et al. | β | 2014 | β |
| Accounting for eXentricities: analysis of the X chromosome in GWAS reveals X-linked genes implicated in autoimmune diseases. | Chang D et al. | β | 2014 | β |
| A common microdeletion affecting a hippocampus- and amygdala-specific isoform of tryptophan hydroxylase 2 is not associated with affective disorders. | Hammer C et al. | β | 2014 | β |
| A comparative analysis of methods for predicting clinical outcomes using high-dimensional genomic datasets. | Jiang X et al. | β | 2014 | β |
| A genome-wide association study identifies major loci affecting the immune response against infectious bronchitis virus in chicken. | Luo C et al. | β | 2014 | β |
| A genome-wide gene-environment interaction analysis for tobacco smoke and lung cancer susceptibility. | Zhang R et al. | β | 2014 | β |
| A method to incorporate prior information into score test for genetic association studies. | Zakharov S et al. | β | 2014 | β |
| A new genotype imputation method with tolerance to high missing rate and rare variants. | Yang Y et al. | β | 2014 | β |
| A novel method for detecting association between DNA methylation and diseases using spatial information. | Yip WK et al. | β | 2014 | β |
| A powerful association test of multiple genetic variants using a random-effects model. | Cheng KF et al. | β | 2014 | β |
| Bayesian systems-based genetic association analysis with effect strength estimation and omic wide interpretation: a case study in rheumatoid arthritis. | HullΓ‘m G et al. | β | 2014 | β |
| Biodemographic Analyses of Longitudinal Data on Aging, Health, and Longevity: Recent Advances and Future Perspectives. | Arbeev KG et al. | β | 2014 | β |
| Challenges and prospects in genome-wide quantitative trait loci mapping of standing genetic variation in natural populations. | Schielzeth H et al. | β | 2014 | β |
| Characterization of biological pathways associated with a 1.37 Mbp genomic region protective of hypertension in Dahl S rats. | Cowley AW et al. | β | 2014 | β |
| Comparison of genotype clustering tools with rare variants. | Perreault LP et al. | β | 2014 | β |
| Detecting local haplotype sharing and haplotype association. | Xu H et al. | β | 2014 | β |
| Detecting rare haplotype-environment interaction with logistic Bayesian LASSO. | Biswas S et al. | β | 2014 | β |
| Discovery in genetic skin disease: the impact of high throughput genetic technologies. | Maruthappu T et al. | β | 2014 | β |
| DNA evidence for strong genetic stability and increasing heritability of intelligence from age 7 to 12. | Trzaskowski M et al. | β | 2014 | β |
| DNA methylation profiles at birth and child ADHD symptoms. | van Mil NH et al. | β | 2014 | β |
| Does genetic heterogeneity account for the divergent risk of type 2 diabetes in South Asian and white European populations? | Sohani ZN et al. | β | 2014 | β |
| Doubling down on genomes: polyploidy and crop plants. | Renny-Byfield S et al. | β | 2014 | β |
| Early developmental conditioning of later health and disease: physiology or pathophysiology? | Hanson MA et al. | β | 2014 | β |
| Emerging technologies advancing forage and turf grass genomics. | KopeckΓ½ D et al. | β | 2014 | β |
| Environment-wide association study (EWAS) for type 2 diabetes in the Marshfield Personalized Medicine Research Project Biobank. | Hall MA et al. | β | 2014 | β |
| EPIQ-efficient detection of SNP-SNP epistatic interactions for quantitative traits. | Arkin Y et al. | β | 2014 | β |
| Epistatic interaction of genetic depression risk variants in the human subgenual cingulate cortex during memory encoding. | Schott BH et al. | β | 2014 | β |
| Estimates of missing heritability for complex traits in Brown Swiss cattle. | RomΓ‘n-Ponce SI et al. | β | 2014 | β |
| Estimating directional epistasis. | Le Rouzic A | β | 2014 | β |
| Estimating heritability of drug-induced liver injury from common variants and implications for future study designs. | Overby CL et al. | β | 2014 | β |
| Experiences in occupational therapy with Afghan clients in Australia. | Maroney P et al. | β | 2014 | β |
| Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants. | van der Valk RJ et al. | β | 2014 | β |
| Gene-environment interaction. | Manuck SB et al. | β | 2014 | β |
| Gene-Gene and Gene-Environment Interactions Underlying Complex Traits and their Detection. | Lou XY | β | 2014 | β |
| Genetic and environmental causes of variation in adolescent anxiety symptoms: a multiple-rater twin study. | Ask H et al. | β | 2014 | β |
| Genetic and environmental continuity in personality development: a meta-analysis. | Briley DA et al. | β | 2014 | β |
| Genetic architecture of cognitive traits. | Le Hellard S et al. | β | 2014 | β |
| Genetic parameters for rennet- and acid-induced coagulation properties in milk from Swedish Red dairy cows. | Gustavsson F et al. | β | 2014 | β |
| Genetics of autoimmunity: an update. | Sorrentino R | β | 2014 | β |
| Genetic studies of Crohn's disease: past, present and future. | Liu JZ et al. | β | 2014 | β |
| Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond. | Grarup N et al. | β | 2014 | β |
| Genome-wide association for growth traits in Canchim beef cattle. | Buzanskas ME et al. | β | 2014 | β |
| Genome-wide association study for egg production and quality in layer chickens. | Wolc A et al. | β | 2014 | β |
| Genome-wide association study of lung function phenotypes in a founder population. | Yao TC et al. | β | 2014 | β |
| Genome-wide eQTLs and heritability for gene expression traits in unrelated individuals. | Yang S et al. | β | 2014 | β |
| Genome-wide interaction study identifies RCBTB1 as a modifier for smoking effect on carotid intima-media thickness. | Wang L et al. | β | 2014 | β |
| Genomic architecture of pharmacological efficacy and adverse events. | Chhibber A et al. | β | 2014 | β |
| Genomics of cardiac electrical function. | Lodder EM et al. | β | 2014 | β |
| GPA: a statistical approach to prioritizing GWAS results by integrating pleiotropy and annotation. | Chung D et al. | β | 2014 | β |
| GWAS-based pathway analysis differentiates between fluid and crystallized intelligence. | Christoforou A et al. | β | 2014 | β |
| High burden of private mutations due to explosive human population growth and purifying selection. | Gao F et al. | β | 2014 | β |
| Identifying rare and common disease associated variants in genomic data using Parkinson's disease as a model. | Lin YC et al. | β | 2014 | β |
| Improving genetic risk prediction by leveraging pleiotropy. | Li C et al. | β | 2014 | β |
| Improving the accuracy of whole genome prediction for complex traits using the results of genome wide association studies. | Zhang Z et al. | β | 2014 | β |
| Jumping on the Train of Personalized Medicine: A Primer for Non-Geneticist Clinicians: Part 2. Fundamental Concepts in Genetic Epidemiology. | Li A et al. | β | 2014 | β |
| Lessons from Genome-Wide Search for Disease-Related Genes with Special Reference to HLA-Disease Associations. | Tokunaga K | β | 2014 | β |
| Logistic Principal Component Analysis for Rare Variants in Gene-Environment Interaction Analysis. | Lu M et al. | β | 2014 | β |
| Low-Frequency Copy-Number Variants and General Cognitive Ability: No Evidence of Association. | Kirkpatrick RM et al. | β | 2014 | β |
| Marker-based estimation of genetic parameters in genomics. | Hu Z et al. | β | 2014 | β |
| Measuring missing heritability: inferring the contribution of common variants. | Golan D et al. | β | 2014 | β |
| Metabolic profiling in diabetes. | Suhre K | β | 2014 | β |
| Moderating the covariance between family member's substance use behavior. | Verhulst B et al. | β | 2014 | β |
| Next generation modeling in GWAS: comparing different genetic architectures. | LΓ³pez de Maturana E et al. | β | 2014 | β |
| On the analysis of a repeated measure design in genome-wide association analysis. | Lee Y et al. | β | 2014 | β |
| Penalized regression approaches to testing for quantitative trait-rare variant association. | Kim S et al. | β | 2014 | β |
| Regularized machine learning in the genetic prediction of complex traits. | Okser S et al. | β | 2014 | β |
| Scrutinizing the epigenetics revolution. | Meloni M et al. | β | 2014 | β |
| Specific glial functions contribute to schizophrenia susceptibility. | Goudriaan A et al. | β | 2014 | β |
| Systems biology strategies to study lipidomes in health and disease. | HyΓΆtylΓ€inen T et al. | β | 2014 | β |
| Targeted resequencing and systematic in vivo functional testing identifies rare variants in MEIS1 as significant contributors to restless legs syndrome. | Schulte EC et al. | β | 2014 | β |
| The Association Between Peer and own Aggression is Moderated by the <i>BDNF</i> Val-met Polymorphism. | Kretschmer T et al. | β | 2014 | β |
| The contribution of genetic and environmental factors to the duration of pregnancy. | York TP et al. | β | 2014 | β |
| The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for GxE research. | Iyegbe C et al. | β | 2014 | β |
| The feasibility of genetic dissection of endophenotypes. | Wilhelmsen KC | β | 2014 | β |
| The genetic interacting landscape of 63 candidate genes in Major Depressive Disorder: an explorative study. | Lekman M et al. | β | 2014 | β |
| The genetics and immunobiology of IgA nephropathy. | Kiryluk K et al. | β | 2014 | β |
| The joint effects of ADH1B variants and childhood adversity on alcohol related phenotypes in African-American and European-American women and men. | Sartor CE et al. | β | 2014 | β |
| The social brain meets the reactive genome: neuroscience, epigenetics and the new social biology. | Meloni M | β | 2014 | β |
| The Usage of an SNP-SNP Relationship Matrix for Best Linear Unbiased Prediction (BLUP) Analysis Using a Community-Based Cohort Study. | Lee YS et al. | β | 2014 | β |
| Twin and family studies reveal strong environmental and weaker genetic cues explaining heritability of eosinophilic esophagitis. | Alexander ES et al. | β | 2014 | β |
| Two families with quadrupedalism, mental retardation, no speech, and infantile hypotonia (Uner Tan Syndrome Type-II); a novel theory for the evolutionary emergence of human bipedalism. | Tan U | β | 2014 | β |
| Two further blood pressure loci identified in ion channel genes with a gene-centric approach. | McCarthy NS et al. | β | 2014 | β |
| Utilising family-based designs for detecting rare variant disease associations. | Preston MD et al. | β | 2014 | β |
| Utilizing population controls in rare-variant case-parent association tests. | Jiang Y et al. | β | 2014 | β |
| A complete mass-spectrometric map of the yeast proteome applied to quantitative trait analysis. | Picotti P et al. | β | 2013 | β |
| An evolutionary perspective on epistasis and the missing heritability. | Hemani G et al. | β | 2013 | β |
| An overview of the genomics of metabolic syndrome. | Taylor JY et al. | β | 2013 | β |
| A one-degree-of-freedom test for supra-multiplicativity of SNP effects. | Herold C et al. | β | 2013 | β |
| A robust model-free approach for rare variants association studies incorporating gene-gene and gene-environmental interactions. | Fan R et al. | β | 2013 | β |
| Association testing of the mitochondrial genome using pedigree data. | Liu C et al. | β | 2013 | β |
| Assumptions and properties of limiting pathway models for analysis of epistasis in complex traits. | Stringer S et al. | β | 2013 | β |
| A SULT2A1 genetic variant identified by GWAS as associated with low serum DHEAS does not impact on the actual DHEA/DHEAS ratio. | Haring R et al. | β | 2013 | β |
| ATHENA: a tool for meta-dimensional analysis applied to genotypes and gene expression data to predict HDL cholesterol levels. | Holzinger ER et al. | β | 2013 | β |
| A unified framework integrating parent-of-origin effects for association study. | Xiao F et al. | β | 2013 | β |
| A unified mixed-effects model for rare-variant association in sequencing studies. | Sun J et al. | β | 2013 | β |
| Avatars of information: towards an inclusive evolutionary synthesis. | Danchin E | β | 2013 | β |
| Bayesian methods applied to GWAS. | Fernando RL et al. | β | 2013 | β |
| Biobanking across the phenome - at the center of chronic disease research. | Imboden M et al. | β | 2013 | β |
| Bridging the genotype-phenotype gap: what does it take? | Gjuvsland AB et al. | β | 2013 | β |
| Bridging the transgenerational gap with epigenetic memory. | Lim JP et al. | β | 2013 | β |
| Bringing genome-wide association findings into clinical use. | Manolio TA | β | 2013 | β |
| Child development and molecular genetics: 14 years later. | Plomin R | β | 2013 | β |
| China's "Gene War of the Century" and Its Aftermath: The Contest Goes On. | Guo SW | β | 2013 | β |
| Combined analysis of three Lynch syndrome cohorts confirms the modifying effects of 8q23.3 and 11q23.1 in MLH1 mutation carriers. | Talseth-Palmer BA et al. | β | 2013 | β |
| Common biological networks underlie genetic risk for alcoholism in African- and European-American populations. | Kos MZ et al. | β | 2013 | β |
| Common DNA markers can account for more than half of the genetic influence on cognitive abilities. | Plomin R et al. | β | 2013 | β |
| Comparison of similarity-based tests and pooling strategies for rare variants. | Zakharov S et al. | β | 2013 | β |
| Complex variation in measures of general intelligence and cognitive change. | Rowe SJ et al. | β | 2013 | β |
| Copy number variation prevalence in known asthma genes and their impact on asthma susceptibility. | Rogers AJ et al. | β | 2013 | β |
| Detecting rare variant effects using extreme phenotype sampling in sequencing association studies. | Barnett IJ et al. | β | 2013 | β |
| Detecting rare variants for psychiatric disorders using next generation sequencing: a methods primer. | Altmann A et al. | β | 2013 | β |
| Detecting rare variants in case-parents association studies. | Cheng KF et al. | β | 2013 | β |
| Development of GMDR-GPU for gene-gene interaction analysis and its application to WTCCC GWAS data for type 2 diabetes. | Zhu Z et al. | β | 2013 | β |
| Encore: Genetic Association Interaction Network centrality pipeline and application to SLE exome data. | Davis NA et al. | β | 2013 | β |
| Epigenetics and crop improvement. | Springer NM | β | 2013 | β |
| Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis. | Lee SH et al. | β | 2013 | β |
| Estimation and partition of heritability in human populations using whole-genome analysis methods. | Vinkhuyzen AA et al. | β | 2013 | β |
| Evaluating empirical bounds on complex disease genetic architecture. | Agarwala V et al. | β | 2013 | β |
| Evaluating rare coding variants as contributing causes to non-syndromic cleft lip and palate. | Leslie EJ et al. | β | 2013 | β |
| Evaluating rare variants in complex disorders using next-generation sequencing. | Ezewudo M et al. | β | 2013 | β |
| Exploring the genetic architecture of circulating 25-hydroxyvitamin D. | Hiraki LT et al. | β | 2013 | β |
| Family-based association analysis of alcohol dependence implicates KIAA0040 on Chromosome 1q in multiplex alcohol dependence families. | Hill SY et al. | β | 2013 | β |
| First genome-wide association study on anxiety-related behaviours in childhood. | Trzaskowski M et al. | β | 2013 | β |
| Frequency of rare allelic variation in candidate genes among individuals with low and high urinary calcium excretion. | Toka HR et al. | β | 2013 | β |
| Genetic insights in Alzheimer's disease. | Bettens K et al. | β | 2013 | β |
| Genetic origin of the relationship between parental negativity and behavior problems from early childhood to adolescence: a longitudinal genetically sensitive study. | Alemany S et al. | β | 2013 | β |
| Genetics of callous-unemotional behavior in children. | Viding E et al. | β | 2013 | β |
| Genetics of eating disorders. | Hinney A et al. | β | 2013 | β |
| Genetics of impulsive behaviour. | Bevilacqua L et al. | β | 2013 | β |
| Genetic variants and their interactions in disease risk prediction - machine learning and network perspectives. | Okser S et al. | β | 2013 | β |
| Genetic variation throughout the folate metabolic pathway influences negative symptom severity in schizophrenia. | Roffman JL et al. | β | 2013 | β |
| Genome-wide association analysis confirms and extends the association of SLC2A9 with serum uric acid levels to Mexican Americans. | Voruganti VS et al. | β | 2013 | β |
| Genome-wide association studies in Alzheimer's disease: a review. | Tosto G et al. | β | 2013 | β |
| Genome-wide association studies in asthma: what they really told us about pathogenesis. | Wjst M et al. | β | 2013 | β |
| Genome-wide complex trait analysis (GCTA): methods, data analyses, and interpretations. | Yang J et al. | β | 2013 | β |
| Genomic analyses with biofilter 2.0: knowledge driven filtering, annotation, and model development. | Pendergrass SA et al. | β | 2013 | β |
| Genotype by environment interactions in cognitive ability: a survey of 14 studies from four countries covering four age groups. | Molenaar D et al. | β | 2013 | β |
| Haplotype kernel association test as a powerful method to identify chromosomal regions harboring uncommon causal variants. | Lin WY et al. | β | 2013 | β |
| Heritability of chronic obstructive pulmonary disease and related phenotypes in smokers. | Zhou JJ et al. | β | 2013 | β |
| How meaningful are heritability estimates of liability? | Benchek PH et al. | β | 2013 | β |
| Identifying proteins controlling key disease signaling pathways. | Gitter A et al. | β | 2013 | β |
| Identifying rare variants associated with complex traits via sequencing. | Li B et al. | β | 2013 | β |
| Implications of sex-specific selection for the genetic basis of disease. | Morrow EH et al. | β | 2013 | β |
| Incorporating genomics into breast and prostate cancer screening: assessing the implications. | Chowdhury S et al. | β | 2013 | β |
| Integrated genomic approaches to enhance genetic resistance in chickens. | Cheng HH et al. | β | 2013 | β |
| Intelligence indexes generalist genes for cognitive abilities. | Trzaskowski M et al. | β | 2013 | β |
| Microarray resources for genetic and genomic studies in chicken: a review. | Gheyas AA et al. | β | 2013 | β |
| Next generation sequencing for neurological diseases: new hope or new hype? | Keogh MJ et al. | β | 2013 | β |
| No genetic influence for childhood behavior problems from DNA analysis. | Trzaskowski M et al. | β | 2013 | β |
| Non-heritable genetics of human disease: spotlight on post-zygotic genetic variation acquired during lifetime. | Forsberg LA et al. | β | 2013 | β |
| Novel common and rare genetic determinants of paraoxonase activity: FTO, SERPINA12, and ITGAL. | Kim DS et al. | β | 2013 | β |
| Overview of Behavioral Genetics Research for Family Researchers. | Samek D et al. | β | 2013 | β |
| Pathway analysis for genome-wide association study of lung cancer in Han Chinese population. | Zhang R et al. | β | 2013 | β |
| Pathway analysis using information from allele-specific gene methylation in genome-wide association studies for bipolar disorder. | Chuang LC et al. | β | 2013 | β |
| Pathway-based analysis using genome-wide association data from a Korean non-small cell lung cancer study. | Lee D et al. | β | 2013 | β |
| Pathway-based approaches for sequencing-based genome-wide association studies. | Wu G et al. | β | 2013 | β |
| Pedigree-free estimates of heritability in the wild: promising prospects for selfing populations. | Gay L et al. | β | 2013 | β |
| Placental contribution to the origins of sexual dimorphism in health and diseases: sex chromosomes and epigenetics. | Gabory A et al. | β | 2013 | β |
| Population growth inflates the per-individual number of deleterious mutations and reduces their mean effect. | Gazave E et al. | β | 2013 | β |
| Prediction of complex human traits using the genomic best linear unbiased predictor. | de Los Campos G et al. | β | 2013 | β |
| PUMA: a unified framework for penalized multiple regression analysis of GWAS data. | Hoffman GE et al. | β | 2013 | β |
| Quantifying missing heritability at known GWAS loci. | Gusev A et al. | β | 2013 | β |
| Quantitative leukocyte BDNF promoter methylation analysis in bipolar disorder. | Strauss JS et al. | β | 2013 | β |
| Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations. | Ding L et al. | β | 2013 | β |
| Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions. | Amin N et al. | β | 2013 | β |
| Republished: Non-heritable genetics of human disease: spotlight on post-zygotic genetic variation acquired during lifetime. | Forsberg LA et al. | β | 2013 | β |
| Role of genetic heterogeneity and epistasis in bladder cancer susceptibility and outcome: a learning classifier system approach. | Urbanowicz RJ et al. | β | 2013 | β |
| Short communication: Accounting for new mutations in genomic prediction models. | Casellas J et al. | β | 2013 | β |
| Single Nucleotide Polymorphism (SNP) Detection and Genotype Calling from Massively Parallel Sequencing (MPS) Data. | Li Y et al. | β | 2013 | β |
| SNPs located at CpG sites modulate genome-epigenome interaction. | Zhi D et al. | β | 2013 | β |
| Systems Biology Approaches and Applications in Obesity, Diabetes, and Cardiovascular Diseases. | Meng Q et al. | β | 2013 | β |
| Systems genetics in "-omics" era: current and future development. | Li H | β | 2013 | β |
| The curse of the missing heritability. | Shen X | β | 2013 | β |
| The evolutionary paradox and the missing heritability of schizophrenia. | van Dongen J et al. | β | 2013 | β |
| The genetics of childhood obesity and interaction with dietary macronutrients. | Garver WS et al. | β | 2013 | β |
| The genetics of infectious disease susceptibility: has the evidence for epistasis been overestimated? | Hall MD et al. | β | 2013 | β |
| The heritability of human disease: estimation, uses and abuses. | Tenesa A et al. | β | 2013 | β |
| The hidden cost of moving up: type 2 diabetes and the escape from persistent poverty in the American South. | Steckel RH | β | 2013 | β |
| The 'missing heritability' of common disorders: should health researchers care? | Chaufan C et al. | β | 2013 | β |
| The new perspectives on genetic studies of type 2 diabetes and thyroid diseases. | Xu M et al. | β | 2013 | β |
| The power of regional heritability analysis for rare and common variant detection: simulations and application to eye biometrical traits. | Uemoto Y et al. | β | 2013 | β |
| The value of statistical or bioinformatics annotation for rare variant association with quantitative trait. | Byrnes AE et al. | β | 2013 | β |
| The VNTR in complex disorders: the forgotten polymorphisms? A functional way forward? | Brookes KJ | β | 2013 | β |
| Translating genome wide association study results to associations among common diseases: in silico study with an electronic medical record. | Anand V et al. | β | 2013 | β |
| Transmission ratio distortion: review of concept and implications for genetic association studies. | Huang LO et al. | β | 2013 | β |
| Ubiquitous polygenicity of human complex traits: genome-wide analysis of 49 traits in Koreans. | Yang J et al. | β | 2013 | β |
| Understanding coronary artery disease using twin studies. | Mangino M et al. | β | 2013 | β |
| Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits. | Zaitlen N et al. | β | 2013 | β |
| Variant discovery in targeted resequencing using whole genome amplified DNA. | Indap AR et al. | β | 2013 | β |
| What have we learnt about the causes of ADHD? | Thapar A et al. | β | 2013 | β |
| Whole-genome sequencing in pharmacogenetics. | Urban TJ | β | 2013 | β |
| 2b-RAD: a simple and flexible method for genome-wide genotyping. | Wang S et al. | β | 2012 | β |
| A likelihood ratio-based Mann-Whitney approach finds novel replicable joint gene action for type 2 diabetes. | Lu Q et al. | β | 2012 | β |
| A multi-SNP locus-association method reveals a substantial fraction of the missing heritability. | Ehret GB et al. | β | 2012 | β |
| An integrated approach to reduce the impact of minor allele frequency and linkage disequilibrium on variable importance measures for genome-wide data. | Walters R et al. | β | 2012 | β |
| A novel approach for the simultaneous analysis of common and rare variants in complex traits. | Yuan A et al. | β | 2012 | β |
| A novel variational Bayes multiple locus Z-statistic for genome-wide association studies with Bayesian model averaging. | Logsdon BA et al. | β | 2012 | β |
| A powerful test for multiple rare variants association studies that incorporates sequencing qualities. | Daye ZJ et al. | β | 2012 | β |
| A quantitative genetic and epigenetic model of complex traits. | Wang Z et al. | β | 2012 | β |
| A risk model for lung cancer incidence. | Hoggart C et al. | β | 2012 | β |
| A simple method for genomic selection of moderately sized dairy cattle populations. | Weller JI et al. | β | 2012 | β |
| Association mapping and disease: evolutionary perspectives. | Besenbacher S et al. | β | 2012 | β |
| ASTN1 and alcohol dependence: family-based association analysis in multiplex alcohol dependence families. | Hill SY et al. | β | 2012 | β |
| Bayesian variable selection in searching for additive and dominant effects in genome-wide data. | Peltola T et al. | β | 2012 | β |
| CCL3L1 copy number and susceptibility to malaria. | Carpenter D et al. | β | 2012 | β |
| Clinical utility of sequence-based genotype compared with that derivable from genotyping arrays. | Morgan AA et al. | β | 2012 | β |
| Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion. | Vinkhuyzen AA et al. | β | 2012 | β |
| Comparison of family history and SNPs for predicting risk of complex disease. | Do CB et al. | β | 2012 | β |
| Complement activation as a biomarker for Alzheimer's disease. | Aiyaz M et al. | β | 2012 | β |
| Computer simulations: tools for population and evolutionary genetics. | Hoban S et al. | β | 2012 | β |
| Current understanding of human genetics and genetic analysis of psoriasis. | Oka A et al. | β | 2012 | β |
| dbPTB: a database for preterm birth. | Uzun A et al. | β | 2012 | β |
| Detecting specific genotype by environment interactions using marginal maximum likelihood estimation in the classical twin design. | Molenaar D et al. | β | 2012 | β |
| Determining genetic risk factors for pediatric type 2 diabetes. | Morgan AR | β | 2012 | β |
| DIFFERENTIAL SUSCEPTIBILITY TO CONTEXT: A PROMISING MODEL OF THE INTERPLAY OF GENES AND THE SOCIAL ENVIRONMENT. | Simons RL et al. | β | 2012 | β |
| Direct-to-Consumer genetic testing: what are we talking about? | Weaver M et al. | β | 2012 | β |
| Diving through the "-omics": the case for deep phenotyping and systems epidemiology. | Haring R et al. | β | 2012 | β |
| Effect of genome-wide genotyping and reference panels on rare variants imputation. | Zheng HF et al. | β | 2012 | β |
| Epigenesis for epidemiologists: does evo-devo have implications for population health research and practice? | Davey Smith G | β | 2012 | β |
| Epigenetic impact of dietary polyphenols in cancer chemoprevention: lifelong remodeling of our epigenomes. | Vanden Berghe W | β | 2012 | β |
| Epigenetics of major psychosis: progress, problems and perspectives. | Labrie V et al. | β | 2012 | β |
| Epistasis and immunity: the role of genetic interactions in autoimmune diseases. | Rose AM et al. | β | 2012 | β |
| Exploiting genomic knowledge in optimising molecular breeding programmes: algorithms from evolutionary computing. | O'Hagan S et al. | β | 2012 | β |
| Footprints in time: comparative quantitative trait loci mapping of the pitcher-plant mosquito, Wyeomyia smithii. | Bradshaw WE et al. | β | 2012 | β |
| From markers to molecular mechanisms: type 1 diabetes in the post-GWAS era. | Baxter AG et al. | β | 2012 | β |
| Gene-independent heritability of behavioural traits: don't we also need to rethink the "environment"? | MΓΌller CP et al. | β | 2012 | β |
| Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development. | Lage K et al. | β | 2012 | β |
| Genetic influences in childhood obesity: recent progress and recommendations for experimental designs. | Fernandez JR et al. | β | 2012 | β |
| Genetic prediction of common diseases. Still no help for the clinical diabetologist! | Prudente S et al. | β | 2012 | β |
| Genetics for clinicians: from candidate genes to whole genome scans (technological advances). | Bochud M | β | 2012 | β |
| Genetics: How intelligence changes with age. | Plomin R | β | 2012 | β |
| Genome-wide and gene-based association implicates FRMD6 in Alzheimer disease. | Hong MG et al. | β | 2012 | β |
| Genome-wide association analysis and genetic architecture of egg weight and egg uniformity in layer chickens. | Wolc A et al. | β | 2012 | β |
| Genome-wide association studies for agronomical traits in a world wide spring barley collection. | Pasam RK et al. | β | 2012 | β |
| GenotypeΓage interaction in human transcriptional ageing. | Kent JW et al. | β | 2012 | β |
| Genotype calling from next-generation sequencing data using haplotype information of reads. | Zhi D et al. | β | 2012 | β |
| Genotype imputation of Metabochip SNPs using a study-specific reference panel of ~4,000 haplotypes in African Americans from the Women's Health Initiative. | Liu EY et al. | β | 2012 | β |
| Heritability and genetic correlations explained by common SNPs for metabolic syndrome traits. | Vattikuti S et al. | β | 2012 | β |
| Heritability in the genome-wide association era. | Zaitlen N et al. | β | 2012 | β |
| High-order SNP combinations associated with complex diseases: efficient discovery, statistical power and functional interactions. | Fang G et al. | β | 2012 | β |
| High-throughput analysis of epistasis in genome-wide association studies with BiForce. | Gyenesei A et al. | β | 2012 | β |
| How genes influence life span: the biodemography of human survival. | Yashin AI et al. | β | 2012 | β |
| Human complex trait genetics: lifting the lid of the genomics toolbox - from pathways to prediction. | Rowe SJ et al. | β | 2012 | β |
| Identification of QTL for UV-protective eye area pigmentation in cattle by progeny phenotyping and genome-wide association analysis. | Pausch H et al. | β | 2012 | β |
| Identification of rare, disease-associated variants in the promoter region of the RNF114 psoriasis susceptibility gene. | Onoufriadis A et al. | β | 2012 | β |
| Independent replication of an association of CNVR7113.6 with Crohn's disease in Caucasians. | Roberts RL et al. | β | 2012 | β |
| IndOR: a new statistical procedure to test for SNP-SNP epistasis in genome-wide association studies. | Emily M | β | 2012 | β |
| Integrated genome-wide pathway association analysis with INTERSNP. | Herold C et al. | β | 2012 | β |
| Integrating genomic and epigenomic information: a promising strategy for identifying functional DNA variants of human disease. | Zaina S et al. | β | 2012 | β |
| Integrating heterogeneous high-throughput data for meta-dimensional pharmacogenomics and disease-related studies. | Holzinger ER et al. | β | 2012 | β |
| Integrative analysis of single nucleotide polymorphisms and gene expression efficiently distinguishes samples from closely related ethnic populations. | Yang HC et al. | β | 2012 | β |
| Joint rare variant association test of the average and individual effects for sequencing studies. | Wang Y et al. | β | 2012 | β |
| Knowledge-driven analysis identifies a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations. | Ma L et al. | β | 2012 | β |
| Kraepelin was right: a latent class analysis of symptom dimensions in patients and controls. | Derks EM et al. | β | 2012 | β |
| Metabolomics in the studies of islet autoimmunity and type 1 diabetes. | Oresic M | β | 2012 | β |
| Monogenic models: what have the single gene disorders taught us? | Klupa T et al. | β | 2012 | β |
| Multiplex meta-analysis of RNA expression to identify genes with variants associated with immune dysfunction. | Morgan AA et al. | β | 2012 | β |
| Natural and orthogonal interaction framework for modeling gene-environment interactions with application to lung cancer. | Ma J et al. | β | 2012 | β |
| Obesity and psychotic disorders: uncovering common mechanisms through metabolomics. | Oresic M | β | 2012 | β |
| Optimal use of regression models in genome-wide association studies. | Powell JE et al. | β | 2012 | β |
| Parameters in dynamic models of complex traits are containers of missing heritability. | Wang Y et al. | β | 2012 | β |
| Partitioning additive genetic variance into genomic and remaining polygenic components for complex traits in dairy cattle. | Jensen J et al. | β | 2012 | β |
| Pathway-based genome-wide association analysis of coronary heart disease identifies biologically important gene sets. | de las Fuentes L et al. | β | 2012 | β |
| Predicting signatures of "synthetic associations" and "natural associations" from empirical patterns of human genetic variation. | Chang D et al. | β | 2012 | β |
| Prioritization based on neutral genetic diversity may fail to conserve important characteristics in cattle breeds. | Hall SJ et al. | β | 2012 | β |
| Psoriasis and other complex trait dermatoses: from Loci to functional pathways. | Capon F et al. | β | 2012 | β |
| Quick, "imputation-free" meta-analysis with proxy-SNPs. | Meesters C et al. | β | 2012 | β |
| Rare and common variants: twenty arguments. | Gibson G | β | 2012 | β |
| Rare variants in complex traits: novel identification strategies and the role of de novo mutations. | Jouan L et al. | β | 2012 | β |
| Rare variants in TMEM132D in a case-control sample for panic disorder. | Quast C et al. | β | 2012 | β |
| Recent explosive human population growth has resulted in an excess of rare genetic variants. | Keinan A et al. | β | 2012 | β |
| Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain. | Richards AL et al. | β | 2012 | β |
| Segment-wise genome-wide association analysis identifies a candidate region associated with schizophrenia in three independent samples. | Gladwin TE et al. | β | 2012 | β |
| Tandem repeat sequence variation as causative cis-eQTLs for protein-coding gene expression variation: the case of CSTB. | Borel C et al. | β | 2012 | β |
| Testing times. | Ware J et al. | β | 2012 | β |
| The Brisbane Systems Genetics Study: genetical genomics meets complex trait genetics. | Powell JE et al. | β | 2012 | β |
| The canid genome: behavioral geneticists' best friend? | Hall NJ et al. | β | 2012 | β |
| The cannabinoid receptor type 2 Q63R variant increases the risk of celiac disease: implication for a novel molecular biomarker and future therapeutic intervention. | Rossi F et al. | β | 2012 | β |
| The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes. | Cusanovich DA et al. | β | 2012 | β |
| The continuing value of twin studies in the omics era. | van Dongen J et al. | β | 2012 | β |
| The extended evolutionary synthesis and the role of soft inheritance in evolution. | Dickins TE et al. | β | 2012 | β |
| The gene in its natural habitat: the importance of gene-trait interactions. | DeYoung CG et al. | β | 2012 | β |
| The genetics of addiction-a translational perspective. | Agrawal A et al. | β | 2012 | β |
| The genetics of attention deficit/hyperactivity disorder in adults, a review. | Franke B et al. | β | 2012 | β |
| The influence of race and ethnicity on the biology of cancer. | Henderson BE et al. | β | 2012 | β |
| The LTE(4) -P2Y12 pathway in asthma. | Cameron L | β | 2012 | β |
| The mystery of missing heritability: Genetic interactions create phantom heritability. | Zuk O et al. | β | 2012 | β |
| The QTN program and the alleles that matter for evolution: all that's gold does not glitter. | Rockman MV | β | 2012 | β |
| The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities. | Ng JW et al. | β | 2012 | β |
| The success of pharmacogenomics in moving genetic association studies from bench to bedside: study design and implementation of precision medicine in the post-GWAS era. | Ritchie MD | β | 2012 | β |
| Twin studies of posttraumatic stress disorder: differentiating vulnerability factors from sequelae. | Kremen WS et al. | β | 2012 | β |
| Ultrafast genome-wide scan for SNP-SNP interactions in common complex disease. | Prabhu S et al. | β | 2012 | β |
| Unraveling the genetic etiology of adult antisocial behavior: a genome-wide association study. | Tielbeek JJ et al. | β | 2012 | β |
| Unveiling case-control relationships in designing a simple and powerful method for detecting gene-gene interactions. | Canela-Xandri O et al. | β | 2012 | β |
| Using summary data from the danish national registers to estimate heritabilities for schizophrenia, bipolar disorder, and major depressive disorder. | Wray NR et al. | β | 2012 | β |
| Using the gene ontology to scan multilevel gene sets for associations in genome wide association studies. | Schaid DJ et al. | β | 2012 | β |
| U-statistics in genetic association studies. | Li H | β | 2012 | β |
| Variation in regulator of G-protein signaling 17 gene (RGS17) is associated with multiple substance dependence diagnoses. | Zhang H et al. | β | 2012 | β |
| Whole-exome sequencing of a pedigree segregating asthma. | DeWan AT et al. | β | 2012 | β |
| Adaptive tests for association analysis of rare variants. | Pan W et al. | β | 2011 | β |
| Adaptive tests for detecting gene-gene and gene-environment interactions. | Pan W et al. | β | 2011 | β |
| After GWAS: searching for genetic risk for schizophrenia and bipolar disorder. | Gershon ES et al. | β | 2011 | β |
| An assessment of the individual and collective effects of variants on height using twins and a developmentally informative study design. | Vrieze SI et al. | β | 2011 | β |
| A new expectation-maximization statistical test for case-control association studies considering rare variants obtained by high-throughput sequencing. | Gordon D et al. | β | 2011 | β |
| A new testing strategy to identify rare variants with either risk or protective effect on disease. | Ionita-Laza I et al. | β | 2011 | β |
| Are languages really independent from genes? If not, what would a genetic bias affecting language diversity look like? | Dediu D | β | 2011 | β |
| Beyond DNA: integrating inclusive inheritance into an extended theory of evolution. | Danchin Γ et al. | β | 2011 | β |
| Beyond missing heritability: prediction of complex traits. | Makowsky R et al. | β | 2011 | β |
| Biomarkers in the age of omics: time for a systems biology approach. | Abu-Asab MS et al. | β | 2011 | β |
| Clinical and functional data implicate the Arg(151)Ser variant of MSX1 in familial hypodontia. | Kamamoto M et al. | β | 2011 | β |
| Commentary: Why are children in the same family so different? Non-shared environment three decades later. | Plomin R | β | 2011 | β |
| Comparative analysis of methods for detecting interacting loci. | Chen L et al. | β | 2011 | β |
| Comparison of six statistics of genetic association regarding their ability to discriminate between causal variants and genetically linked markers. | Lorenzo Bermejo J et al. | β | 2011 | β |
| Comparison of statistical tests for disease association with rare variants. | Basu S et al. | β | 2011 | β |
| Comparison of strategies to detect epistasis from eQTL data. | Kapur K et al. | β | 2011 | β |
| Defective innate immunity in inflammatory bowel disease: a Crohn's disease exclusivity? | Marks DJ | β | 2011 | β |
| Detection of common single nucleotide polymorphisms synthesizing quantitative trait association of rarer causal variants. | Takeuchi F et al. | β | 2011 | β |
| Detection of intergenerational genetic effects with application to HLA-B matching as a risk factor for schizophrenia. | Childs EJ et al. | β | 2011 | β |
| Developmental origins of noncommunicable disease: population and public health implications. | Hanson M et al. | β | 2011 | β |
| Different models of genetic variation and their effect on genomic evaluation. | Clark SA et al. | β | 2011 | β |
| Digging into the extremes: a useful approach for the analysis of rare variants with continuous traits? | Lamina C | β | 2011 | β |
| Do rare variant genotypes predict common variant genotypes? | Kent JW et al. | β | 2011 | β |
| Early prenatal stress epigenetically programs dysmasculinization in second-generation offspring via the paternal lineage. | Morgan CP et al. | β | 2011 | β |
| Enriching targeted sequencing experiments for rare disease alleles. | Edwards TL et al. | β | 2011 | β |
| Environment-sensitive epigenetics and the heritability of complex diseases. | Furrow RE et al. | β | 2011 | β |
| Epidemiology, epigenetics and the 'Gloomy Prospect': embracing randomness in population health research and practice. | Smith GD | β | 2011 | β |
| Estimating missing heritability for disease from genome-wide association studies. | Lee SH et al. | β | 2011 | β |
| Evaluation of the gene-age interactions in HDL cholesterol, LDL cholesterol, and triglyceride levels: the impact of the SORT1 polymorphism on LDL cholesterol levels is age dependent. | Shirts BH et al. | β | 2011 | β |
| Explaining the heritability of an ecologically significant trait in terms of individual quantitative trait loci. | Scoville AG et al. | β | 2011 | β |
| Family-based designs for genome-wide association studies. | Ott J et al. | β | 2011 | β |
| GCTA: a tool for genome-wide complex trait analysis. | Yang J et al. | β | 2011 | β |
| Gene-by-environment experiments: a new approach to finding the missing heritability. | van Ijzendoorn MH et al. | β | 2011 | β |
| Gene-environment interactions in human disease: nuisance or opportunity? | Ober C et al. | β | 2011 | β |
| Genetic effects at pleiotropic loci are context-dependent with consequences for the maintenance of genetic variation in populations. | Lawson HA et al. | β | 2011 | β |
| Genetic risks and childhood-onset asthma. | Cookson W et al. | β | 2011 | β |
| Genetic risk sum score comprised of common polygenic variation is associated with body mass index. | Peterson RE et al. | β | 2011 | β |
| Genetics of ACPA-positive rheumatoid arthritis: the beginning of the end? | de Vries RR et al. | β | 2011 | β |
| Genetics of bipolar disorder. | Wendland JR et al. | β | 2011 | β |
| Genetics of rheumatoid arthritis: time for a change! | de Vries R | β | 2011 | β |
| Genetic variations and associated pathophysiology in the management of epilepsy. | Mulley JC et al. | β | 2011 | β |
| Genome-wide investigation of rare structural variants identifies VIPR2 as a new candidate gene for schizophrenia. | Nieratschker V et al. | β | 2011 | β |
| Genomic inflation factors under polygenic inheritance. | Yang J et al. | β | 2011 | β |
| Grand challenge in behavioral and psychiatric genetics: quantitative challenges to keeping up with molecular advances. | Knopik VS | β | 2011 | β |
| Haplotype analysis improved evidence for candidate genes for intramuscular fat percentage from a genome wide association study of cattle. | Barendse W | β | 2011 | β |
| High throughput analyses of epistasis for swine body dimensions and organ weights. | Wei WH et al. | β | 2011 | β |
| Human genetics and genomics a decade after the release of the draft sequence of the human genome. | Naidoo N et al. | β | 2011 | β |
| Human TLRs and IL-1Rs in host defense: natural insights from evolutionary, epidemiological, and clinical genetics. | Casanova JL et al. | β | 2011 | β |
| Identity-by-descent filtering as a tool for the identification of disease alleles in exome sequence data from distant relatives. | Akula N et al. | β | 2011 | β |
| Inflammatory bowel disease aggregation in Utah kindreds. | Guthery SL et al. | β | 2011 | β |
| Invited review: quantitative trait nucleotide determination in the era of genomic selection. | Weller JI et al. | β | 2011 | β |
| Is gastroschisis truly a sporadic defect?: familial cases of gastroschisis in Utah, 1997 to 2008. | Feldkamp ML et al. | β | 2011 | β |
| Knowledge-driven multi-locus analysis reveals gene-gene interactions influencing HDL cholesterol level in two independent EMR-linked biobanks. | Turner SD et al. | β | 2011 | β |
| Look beyond one's own nose: combination of information from publicly available sources reveals an association of GATA4 polymorphisms with plasma triglycerides. | Lamina C et al. | β | 2011 | β |
| Low-coverage sequencing: implications for design of complex trait association studies. | Li Y et al. | β | 2011 | β |
| Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes. | Pers TH et al. | β | 2011 | β |
| Mining the LIPG allelic spectrum reveals the contribution of rare and common regulatory variants to HDL cholesterol. | Khetarpal SA et al. | β | 2011 | β |
| Modeling interactions with known risk loci-a Bayesian model averaging approach. | Ferreira T et al. | β | 2011 | β |
| Multivariate analysis of regulatory SNPs: empowering personal genomics by considering cis-epistasis and heterogeneity. | Turner SD et al. | β | 2011 | β |
| Necessary advances in exercise genomics and likely pitfalls. | Pitsiladis Y et al. | β | 2011 | β |
| Novel method to estimate the phenotypic variation explained by genome-wide association studies reveals large fraction of the missing heritability. | Kutalik Z et al. | β | 2011 | β |
| On statistical methods for estimating heritability in wild populations. | SillanpÀÀ MJ | β | 2011 | β |
| Overview of techniques to account for confounding due to population stratification and cryptic relatedness in genomic data association analyses. | SillanpÀÀ MJ | β | 2011 | β |
| Pathway-Wide Association Study Implicates Multiple Sterol Transport and Metabolism Genes in HDL Cholesterol Regulation. | Wang K et al. | β | 2011 | β |
| Performance analysis of novel methods for detecting epistasis. | Shang J et al. | β | 2011 | β |
| Perioperative genomics. | Nagele P | β | 2011 | β |
| Personalized medicine: new genomics, old lessons. | Offit K | β | 2011 | β |
| Polygenic modeling of genome-wide association studies: an application to prostate and breast cancer. | Witte JS et al. | β | 2011 | β |
| Population-based and family-based designs to analyze rare variants in complex diseases. | Kazma R et al. | β | 2011 | β |
| Predicting genetic values: a kernel-based best linear unbiased prediction with genomic data. | Ober U et al. | β | 2011 | β |
| Predicting sensation seeking from dopamine genes: use and misuse of genetic prediction. | Powell JE et al. | β | 2011 | β |
| Quantifying the underestimation of relative risks from genome-wide association studies. | Spencer C et al. | β | 2011 | β |
| Quantitative epigenetics through epigenomic perturbation of isogenic lines. | Johannes F et al. | β | 2011 | β |
| Rapid recent human evolution and the accumulation of balanced genetic polymorphisms. | Wills C | β | 2011 | β |
| Relationship between genomic distance-based regression and kernel machine regression for multi-marker association testing. | Pan W | β | 2011 | β |
| Searching for the missing heritability. | Watson NF | β | 2011 | β |
| Serotonin transporter promoter region (5-HTTLPR) polymorphism predicts resting respiratory sinus arrhythmia. | Ellis AJ et al. | β | 2011 | β |
| Significance levels in genome-wide interaction analysis (GWIA). | Becker T et al. | β | 2011 | β |
| Single Nucleotide Polymorphisms in the Insulin-Like Growth Factor 1 (IGF-1) Gene are Associated with Performance in Holstein-Friesian Dairy Cattle. | Mullen MP et al. | β | 2011 | β |
| Single-tissue and cross-tissue heritability of gene expression via identity-by-descent in related or unrelated individuals. | Price AL et al. | β | 2011 | β |
| Statistical analysis of rare sequence variants: an overview of collapsing methods. | Dering C et al. | β | 2011 | β |
| Statistical Optimization of Pharmacogenomics Association Studies: Key Considerations from Study Design to Analysis. | Grady BJ et al. | β | 2011 | β |
| Study designs for identification of rare disease variants in complex diseases: the utility of family-based designs. | Ionita-Laza I et al. | β | 2011 | β |
| Synthetic associations created by rare variants do not explain most GWAS results. | Wray NR et al. | β | 2011 | β |
| T2DM: Why Epigenetics? | Fradin D et al. | β | 2011 | β |
| Technology-specific error signatures in the 1000 Genomes Project data. | Nothnagel M et al. | β | 2011 | β |
| The effect of chromosome 9p21 variants on cardiovascular disease may be modified by dietary intake: evidence from a case/control and a prospective study. | Do R et al. | β | 2011 | β |
| The genetics of asthma and allergic disease: a 21st century perspective. | Ober C et al. | β | 2011 | β |
| The genetics of common kidney disease: a pathway toward clinical relevance. | Drawz PE et al. | β | 2011 | β |
| The integration of 'omic' disciplines and systems biology in cattle breeding. | Berry DP et al. | β | 2011 | β |
| Toward knowing the whole human: next-generation sequencing for personalized medicine. | Toma I et al. | β | 2011 | β |
| Two-stage design of sequencing studies for testing association with rare variants. | Yang F et al. | β | 2011 | β |
| Understanding risk for psychopathology through imaging gene-environment interactions. | Hyde LW et al. | β | 2011 | β |
| Using biological knowledge to uncover the mystery in the search for epistasis in genome-wide association studies. | Ritchie MD | β | 2011 | β |
| Using extreme phenotype sampling to identify the rare causal variants of quantitative traits in association studies. | Li D et al. | β | 2011 | β |
| Using LASSO regression to detect predictive aggregate effects in genetic studies. | Fontanarosa JB et al. | β | 2011 | β |
| Using the posterior distribution of deviance to measure evidence of association for rare susceptibility variants. | Lorenzo-Bermejo J et al. | β | 2011 | β |
| vipR: variant identification in pooled DNA using R. | Altmann A et al. | β | 2011 | β |
| What can exome sequencing do for you? | Majewski J et al. | β | 2011 | β |
| Whole-genome association study for fatty acid composition of oleic acid in Japanese Black cattle. | Uemoto Y et al. | β | 2011 | β |
| A commentary on 'common SNPs explain a large proportion of the heritability for human height' by Yang et al. (2010). | Visscher PM et al. | β | 2010 | β |
| A genome-wide association study of Cloninger's temperament scales: implications for the evolutionary genetics of personality. | Verweij KJ et al. | β | 2010 | β |
| Ancestral paternal genotype controls body weight and food intake for multiple generations. | Yazbek SN et al. | β | 2010 | β |
| An evolutionary framework for association testing in resequencing studies. | King CR et al. | β | 2010 | β |
| Assessment of effectiveness of the network-guided genetic screen. | Kim E et al. | β | 2010 | β |
| ATHENA: A knowledge-based hybrid backpropagation-grammatical evolution neural network algorithm for discovering epistasis among quantitative trait Loci. | Turner SD et al. | β | 2010 | β |
| Comparison of multimarker logistic regression models, with application to a genomewide scan of schizophrenia. | Wason JM et al. | β | 2010 | β |
| Disease-associated alleles in genome-wide association studies are enriched for derived low frequency alleles relative to HapMap and neutral expectations. | Lachance J | β | 2010 | β |
| From GWAS to the clinic: risk factors for intracranial aneurysms. | Ruigrok YM et al. | β | 2010 | β |
| From single genes to gene networks: high-throughput-high-content screening for neurological disease. | Jain S et al. | β | 2010 | β |
| Genetically complex epilepsies, copy number variants and syndrome constellations. | Mefford HC et al. | β | 2010 | β |
| Genetic architecture of complex traits and accuracy of genomic prediction: coat colour, milk-fat percentage, and type in Holstein cattle as contrasting model traits. | Hayes BJ et al. | β | 2010 | β |
| Genetic self knowledge and the future of epidemiologic confounding. | VanderWeele TJ | β | 2010 | β |
| Genetic variants and their interactions in the prediction of increased pre-clinical carotid atherosclerosis: the cardiovascular risk in young Finns study. | Okser S et al. | β | 2010 | β |
| Genome-wide association study for colorectal cancer identifies risk polymorphisms in German familial cases and implicates MAPK signalling pathways in disease susceptibility. | Lascorz J et al. | β | 2010 | β |
| Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene. | Kapur K et al. | β | 2010 | β |
| Investigation and functional characterization of rare genetic variants in the adipose triglyceride lipase in a large healthy working population. | Coassin S et al. | β | 2010 | β |
| Joint influence of small-effect genetic variants on human longevity. | Yashin AI et al. | β | 2010 | β |
| Joint linkage-linkage disequilibrium mapping is a powerful approach to detecting quantitative trait loci underlying drought tolerance in maize. | Lu Y et al. | β | 2010 | β |
| Life-threatening infectious diseases of childhood: single-gene inborn errors of immunity? | AlcaΓ―s A et al. | β | 2010 | β |
| Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans. | Saccone NL et al. | β | 2010 | β |
| Nature or nurture: let food be your epigenetic medicine in chronic inflammatory disorders. | Szarc vel Szic K et al. | β | 2010 | β |
| Non-Mendelian epigenetic heredity: gametic RNAs as epigenetic regulators and transgenerational signals. | Cuzin F et al. | β | 2010 | β |
| Nutrigenomics: where are we with genetic and epigenetic markers for disposition and susceptibility? | Kussmann M et al. | β | 2010 | β |
| Nutrition, epigenetics, and developmental plasticity: implications for understanding human disease. | Burdge GC et al. | β | 2010 | β |
| Peer substance involvement modifies genetic influences on regular substance involvement in young women. | Agrawal A et al. | β | 2010 | β |
| Phenomics: the next challenge. | Houle D et al. | β | 2010 | β |
| Phenotypic complexity, measurement bias, and poor phenotypic resolution contribute to the missing heritability problem in genetic association studies. | van der Sluis S et al. | β | 2010 | β |
| Powerful multi-marker association tests: unifying genomic distance-based regression and logistic regression. | Han F et al. | β | 2010 | β |
| Predicting genetic predisposition in humans: the promise of whole-genome markers. | de los Campos G et al. | β | 2010 | β |
| Predicting sensation seeking from dopamine genes. A candidate-system approach. | Derringer J et al. | β | 2010 | β |
| Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis. | Bowes J et al. | β | 2010 | β |
| Reconciling the analysis of IBD and IBS in complex trait studies. | Powell JE et al. | β | 2010 | β |
| Synthetic associations in the context of genome-wide association scan signals. | Orozco G et al. | β | 2010 | β |
| The genetics of type 2 diabetes: what have we learned from GWAS? | Billings LK et al. | β | 2010 | β |
| To identify associations with rare variants, just WHaIT: Weighted haplotype and imputation-based tests. | Li Y et al. | β | 2010 | β |
| Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples. | Kell DB | β | 2010 | β |
| Transgenerational genetic effects of the paternal Y chromosome on daughters' phenotypes. | Nelson VR et al. | β | 2010 | β |
| USING POPULATION GENOMICS TO DETECT SELECTION IN NATURAL POPULATIONS: KEY CONCEPTS AND METHODOLOGICAL CONSIDERATIONS. | Hohenlohe PA et al. | β | 2010 | β |
| Variance heterogeneity analysis for detection of potentially interacting genetic loci: method and its limitations. | Struchalin MV et al. | β | 2010 | β |