Ultrasensitive fluorescent proteins for imaging neuronal activity.

paper Cited Public

Authors: Chen, Tsai-Wen; Wardill, Trevor J; Sun, Yi; Pulver, Stefan R; Renninger, Sabine L; Baohan, Amy; Schreiter, Eric R; Kerr, Rex A; Orger, Michael B; Jayaraman, Vivek; Looger, Loren L; Svoboda, Karel; Kim, Douglas S
Year: 2013
Journal: Nature
PMID: 23868258
DOI: 10.1038/nature12354
PMCID: PMC3777791

Figure 1

GCaMP mutagenesis and screening in dissociated neuronsa, GCaMP structure27,64 and mutations in different GCaMP variants relative to GCaMP5G.b, Responses averaged across multiple neurons and wells for GCaMP3, 5G, 6f, 6m, 6s, and OGB1-AM. Top, fluorescence changes in response to 1 action potential. Bottom, 10 action potentials.c, Screening results, 447 GCaMPs. Top, fluorescence change in response to 1 action potential (vertical bars, ΔF/F0; green bar, OGB1-AM, left; black bars, single GCaMP mutations; red bars, combinatorial mutations; blue, GCaMP6 indicators) and significance values for different action potential stimuli (color plot). Middle, half decay time after 10 action potentials. Bottom, resting fluorescence, F0 normalized to nuclear mCherry fluorescence. Red line, GCaMP3 level; green line, GCaMP5G level; blue line, OGB1-AM level.d-g, Comparison of GCaMP sensors and OGB1-AM (blue) as a function of stimulus strength (colors as in b). d, response amplitude; e, SNR; f, half decay time; g, time to peak (after stimulus offset). Error bars correspond to s.e.m (n=300, 16, 8, 11, 13, 11 wells for GCaMP3, GCaMP5G, OGB1-AM, 6f, 6m, 6s, respectively).

LLM interpretation

This figure presents the development and screening of GCaMP variants. Panel **a** shows a protein structure diagram and a table of mutations, while panel **b** uses line graphs to show fluorescence changes ($\Delta F/F_0$) over time for various sensors in response to 1 and 10 action potentials. Panel **c** displays screening results for 447 GCaMPs using bar charts and a color plot to compare response amplitude, decay time, and resting fluorescence. Panels **d-g** use scatter plots with error bars to compare response amplitude, SNR, decay time, and rise time across sensors as a function of the number of action potentials.

Figure 2

GCaMP6 performance in the mouse visual cortexa, Top, schematic of the experiment. Bottom, field of view showing neurons color-coded according to their preferred orientation (hue) and response amplitude (brightness) for GCaMP5G (left) and GCaMP6s (right).b, Example traces from three neurons expressing GCaMP6s. Single sweeps (grey) and averages of 5 sweeps (black) are overlaid. Directions of grating motion (8 directions) are shown above traces (arrows).c, Example traces from three neurons expressing GCaMP6f. Single sweeps (grey) and averages of 5 sweeps (cyan) are overlaid.d, Top, high magnification view of fluorescence changes corresponding to the red boxes in b (black) and c (cyan), normalized to the peak of the response. Bottom, Fourier spectra normalized to the response amplitude at 0 Hz for neurons driven with 1 Hz drifting gratings, transduced with GCaMP5G, OGB1-AM, 6f, 6s.e, The fraction of cells scored as responding to visual stimulation when loaded with different calcium indicators. Error bars correspond to s.e.m. (n=70, 39, 23, 38, 21, 34 FOVs for GCaMP3, 5G, OGB1-AM, 6f, 6m, 6s, respectively). GCaMP3, 5G, and OGB1-AM data are from ref 16.f, The distribution of fluorescence changes across cells at the preferred orientation.

LLM interpretation

This figure evaluates GCaMP6 performance in the mouse visual cortex through a combination of imaging and quantitative analysis. It includes a schematic of the experimental setup (a), fluorescence images of neurons color-coded by orientation preference (a), and example calcium traces for GCaMP6s and GCaMP6f (b, c). Quantitative data are presented as normalized Fourier spectra of fluorescence changes (d), a bar chart comparing the fraction of responsive cells across different indicators (e), and a cumulative probability distribution of fluorescence changes at preferred stimuli (f).

Figure 3

Combined imaging and electrophysiology in the visual cortexa, Simultaneous fluorescence dynamics and spikes in a GCaMP6s (top) and a GCaMP6f (bottom) expressing neuron. The number of spikes for each burst is indicated below the trace (single spikes are indicated by asterisks). Left inset, a GCaMP6s expressing neuron with the recording pipette indicated schematically.b, Zoomed-in view of bursts of action potentials. Top, GCaMP6s; bottom, GCaMP6f.c, Fluorescence change in response to one action potential. Top, GCaMP6s; bottom, GCaMP6f.d, Median fluorescence change in response to one action potential for different calcium indicators. Shading corresponds to s.e.m., n= 9 (GCaMP5K, data from ref 16), 11 (GCaMP6f), 10 (GCaMP6m), 9 (GCaMP6s) cells. GCaMP5K and GCaMP5G have similar properties16.e, Peak fluorescence change as a function of number of action potentials in a 250 ms bin (5K: n=161, 65, 22, 4 events for 1, 2, 3, 4 action potentials; 6f: n=366, 120, 50, 15, 7 events for 1, 2, 3, 4, 5 action potentials; 6m: n=354, 105, 31, 11, 7 events for 1, 2, 3, 4, 5 action potential; 6s: n=250, 60, 20, 5, 4 events for 1, 2, 3, 4, 5 action potentials). Error bars correspond to s.e.m.f, Comparison of GCaMP indicators. Left, fraction of isolated spikes detected at 1% false positive rate. Middle, half decay time. Right, rise time to peak. Error bars correspond to s.e.m.

LLM interpretation

This figure presents a comparison of GCaMP calcium indicators (5K, 6f, 6m, 6s) using simultaneous fluorescence imaging and electrophysiology in the visual cortex. Panels **a-c** show fluorescence traces and zoomed-in views of action potential bursts for GCaMP6s and 6f, while panel **d** compares the median fluorescence change for one action potential across indicators. Panels **e** and **f** utilize line and bar charts to quantify peak fluorescence relative to spike count, the percentage of isolated spikes detected, half-decay time, and rise time to peak, with error bars representing s.e.m.

Figure 4

Imaging activity in dendritic spines in the visual cortexa, Image of an L2/3 dendritic branch expressing GCaMP6s. Regions of interest (ROIs) are indicated as dashed circles (red, spines; yellow, dendrites).b, Map of fluorescence change (ΔF=Fresponse-Fbaseline) in response to drifting gratings of 8 different orientations.c, Pixel-based map of orientation preference.d, Responses of dendritic spines (s1-s3) and neighboring dendritic shafts (d1-d3) to drifting gratings with different orientations (corresponding to ROIs indicated in a).e, Orientation tuning of individual spines (s1, s2, s3). Error bars correspond to s.e.m. (n=5 trials).f, Fraction of spines that show detectable calcium transients (active) and respond to visual stimulation (responsive) (see Methods for definitions) (228 spines; 15 dendrites; 4 mice).g, Distribution of the orientation selectivity index across visually responsive spines (62 spines).h, Baseline fluorescence across individual dendritic spines over 320 seconds of continuous imaging (228 spines; 15 dendrites; 4 mice; error bars reflect s.e.m. across spines).i, Left, the same GCaMP6s labeled spine imaged over weeks. Right, fluorescence responses to oriented drifting gratings. Insets, parent soma of imaged spines.j, Orientation selectivity of single spines measured over time (same as i).k, Top, preferred orientation for spines that responded in two imaging sessions separated by one week. Opposing stimulus directions are considered as equivalent in this analysis. Bottom, the distribution of ΔOri (difference in preferred orientation between two sessions).

LLM interpretation

This multi-panel figure presents GCaMP6s calcium imaging data from L2/3 dendritic spines in the visual cortex. It includes microscopy images of dendritic branches (a, i), fluorescence maps of orientation preference (b, c), and time-series traces showing spine-specific responses to drifting gratings (d, i). Quantitative analyses include orientation tuning curves (e, j), histograms of spine activity and selectivity (f, g), baseline stability (h), and the longitudinal stability of preferred orientations over several weeks (k).

Figure 5

The orientation preference of populations of dendritic spines predicts the orientation preference of their parent neurona, Somatic fluorescence responses of a GCaMP6s-expressing layer 2/3 pyramidal neuron (depth, 120 μm) to oriented drifting gratings (Top) and the corresponding tuning curve (Bottom, normalized).b, Reconstruction of the dendritic arbor (red dendrites, dendrites shown in d; dashed squares, additional imaged regions).c, Top, fluorescence responses of visually responsive spines (84/298) sorted by their preferred orientation (averaged over 5 trials). Each row shows one spine normalized to its peak. Bottom, summed ΔF/F0 across all spines (without normalization).d, Locations of orientation selective spines on a subset of imaged dendrites (corresponding to red dendrites in b). The size of the circle corresponds to the averaged ΔF/F0 at the preferred stimulus, the color indicates the preferred orientation, and the saturation of the color encodes the orientation selectivity index (OSI =1, saturated color; OSI=0, white).e, Top, tuning curve of somatic ΔF/F. Bottom, summed spine ΔF/F. Cell 1 corresponds to panels a-d.f, Averaged output tuning (black) and integral spine response (gray) across the 5 neurons (same cells as in e). The turning curves were aligned to the preferred orientation of the output response (0 degree). The average was normalized.g, The distribution of preferred orientation of dendritic spines (5 cells; number of spines sampled: 298,166,137,278,116).h, Fraction of visually responsive spines preferring orientations 0, 45 or 90 degree away from the postsynaptic cell's preferred orientation. Opposing stimulus directions are considered as equivalent in this analysis. Error bars correspond to s.e.m.

LLM interpretation

This multi-panel figure analyzes the relationship between dendritic spine orientation preference and the somatic response of layer 2/3 pyramidal neurons. It includes fluorescence traces and tuning curves for somatic and spine responses (a, c, e), a dendritic arbor reconstruction with color-coded selective spines (b, d), and averaged tuning curves comparing output and integral spine responses (f). Quantitative analysis is shown via histograms of spine orientation preferences (g) and a bar chart (h) indicating that a higher fraction of responsive spines prefer orientations close to the parent neuron's preferred orientation.

Figure 6

Orientation-tuned domains in dendrites of GABAergic interneuronsa, A GCaMP6s-expressing interneuron (soma depth, 250 μm), identified post hoc as a parvalbumin-positive interneuron.b, Somatic fluorescence changes to oriented drifting grating (same cell as in a). Bottom, polar plot.c, Reconstruction of the dendritic arbor based on GCaMP6s fluorescence.d, Left, a dendrite of the cell (red in c) was imaged along its entire length. Colored squares indicate dendritic sites showing significant orientation tuning (p < 0.01, ANOVA across 8 stimulus directions). The color of each square indicates the local preferred orientation, and the saturation of the color encodes the orientation selectivity index (OSI =1, saturated color; OSI=0, white). Right, example dendritic fluorescence changes and the corresponding polar plots for four locations with distinct orientation preferences. Scale bars: 10s; 50% ΔF/F.e, Zoomed-in view of the dendritic calcium signal corresponding to the box in d. The signal shows modulation at the frequency of the drifting grating (1 Hz).

LLM interpretation

This figure presents calcium imaging data from a parvalbumin-positive GABAergic interneuron, featuring microscopy images of the cell (a), its dendritic reconstruction (c), and its response to oriented drifting gratings. The somatic response (b) shows low orientation selectivity, while the dendritic analysis (d) reveals spatially distinct domains with significant orientation tuning ($p < 0.01$), indicated by colored squares along the dendrite and corresponding polar plots. Panel (e) provides a zoomed-in view of a dendritic calcium signal showing modulation at the 1 Hz frequency of the stimulus.

#	Section	Preview
0	Introduction	Neural activity causes rapid changes in intracellular free calcium1-4. Calcium imaging experiments…
1	Introduction	Calcium indicator proteins include the single fluorophore sensor GCaMP11,16,17 and several families…
2	Introduction	Multiple rounds of structure-guided design have made GCaMPs the most widely used protein calcium…
3	Introduction — GCaMP protein engineering	GCaMP17 and its progeny11,16 consist of circularly permuted green fluorescent protein (cpGFP)25, the…
4	Introduction — GCaMP protein engineering	We produced numerous additional GCaMP variants and tested them in automated neuronal assays (Fig.…
5	Introduction — GCaMP protein engineering	Dissociated rat hippocampal neurons in 24-well plates were transduced with GCaMP variants (one per…
6	Introduction — GCaMP protein engineering	The assay revealed 43/348 point mutants with improved sensitivity compared to GCaMP3 (ΔF/F0 in…
7	Introduction — GCaMP protein engineering	Based on screening in cultured neurons (Fig. 1), we chose three ultrasensitive GCaMP6 sensors…
8	Introduction — GCaMP protein engineering	and 1.7-fold faster decay time than GCaMP5G (Fig. 1f, g) (Supplementary Table 1). GCaMP6f is the…
9	Introduction — Imaging neuronal populations in the mouse visual cortex	We next tested GCaMP6 in layer (L)2/3 pyramidal neurons in the mouse visual cortex V1 in vivo (Fig.…
10	Introduction — Imaging neuronal populations in the mouse visual cortex	GCaMP6 performance was compared to other sensors in several ways. The fraction of responding neurons…
11	Introduction — Imaging neuronal populations in the mouse visual cortex	We imaged GCaMP6s-expressing neurons through a chronic imaging window6,31 over several weeks in V1…
12	Introduction — Imaging neuronal populations in the mouse visual cortex	We directly compared cellular fluorescence changes and spiking using loose-seal, cell-attached…
13	Introduction — Calcium transients in dendritic spines	Pyramidal neuron output is shaped by thousands of excitatory synapses distributed across the…
14	Introduction — Calcium transients in dendritic spines	neurons originates from (presumably orientation-tuned) V1 neurons34. Neighboring spines were often…
15	Introduction — Calcium transients in dendritic spines	We imaged the same dendritic segments over imaging sessions separated by weeks. Most spines…
16	Introduction — Calcium transients in dendritic spines	How orientation-tuned neurons connect to other orientation-tuned neurons remains controversial10,35.…
17	Introduction — Calcium transients in dendritic spines	averaged across all spines was biased towards the orientation tuning of the parent neurons (Fig. 5e,…
18	Introduction — Calcium transients in GABAergic dendrites	Consistent with previous results40,41, somatic fluorescence changes in GABAergic neurons were…
19	Introduction — Calcium transients in GABAergic dendrites	We mapped the visual response along 104 interneuron dendrites (total imaged length 6.3 mm) with…

Citation	PMID	DOI	Status
Akerboom, J, Front Mol Neurosci, 2013, Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics	23459413	10.3389/fnmol.2013.00002	Cited
Akerboom, J, J Biol Chem, 2009, Crystal structures of the GCaMP calcium sensor reveal the mechanism of fluorescence signal change and aid rational design	19098007	10.1074/jbc.M807657200	Cited
Akerboom, J, J Neurosci, 2012, Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging	23035093	10.1523/JNEUROSCI.2601-12.2012	Cited
Baird, GS et al., Proc Natl Acad Sci USA, 1999, Circular permutation and receptor insertion within green fluorescent proteins	10500161	10.1073/pnas.96.20.11241	Cited
Baker, PF et al., J Physiol, 1971, Depolarization and calcium entry in squid giant axons	5133953	10.1113/jphysiol.1971.sp009641	Cited
Bandyopadhyay, S et al., Nat Neurosci, 2010, Dichotomy of functional organization in the mouse auditory cortex	20118924	10.1038/nn.2490	Cited
Bayley, PM et al., Protein Sci, 1996, Target recognition by calmodulin: dissecting the kinetics and affinity of interaction using short peptide sequences	8819155	10.1002/pro.5560050701	Cited
Binzegger, T et al., J Neurosci, 2004, A quantitative map of the circuit of cat primary visual cortex	15456817	10.1523/JNEUROSCI.1400-04.2004	Cited
Bock, DD, Nature, 2011, Network anatomy and in vivo physiology of visual cortical neurons	21390124	10.1038/nature09802	Cited
Brainard, DH, Spatial vision, 1997, The Psychophysics Toolbox	9176952	—	Cited
Chen, X et al., Nature, 2011, Functional mapping of single spines in cortical neurons in vivo	21706031	10.1038/nature10193	Cited
Crivici, A et al., Annu Rev Biophys Biomol Struct, 1995, Molecular and structural basis of target recognition by calmodulin	7663132	10.1146/annurev.bb.24.060195.000505	Cited
Dreosti, E et al., Nat Methods, 2009, A genetically encoded reporter of synaptic activity in vivo	19898484	10.1038/nmeth.1399	Cited
Gibson, DG, Nat Methods, 2009, Enzymatic assembly of DNA molecules up to several hundred kilobases	19363495	10.1038/nmeth.1318	Cited
Goldberg, JH et al., J Physiol, 2003, Ca2+ imaging of mouse neocortical interneurone dendrites: Ia-type K+ channels control action potential backpropagation	12844506	10.1113/jphysiol.2003.042580	Cited
Goldberg, JH et al., Neuron, 2003, Calcium microdomains in aspiny dendrites	14622584	10.1016/s0896-6273(03)00714-1	Cited
Guerrero, G, Nat Neurosci, 2005, Heterogeneity in synaptic transmission along a Drosophila larval motor axon	16116446	10.1038/nn1526	Cited
Gulyas, AI et al., J Neurosci, 1999, Total number and ratio of excitatory and inhibitory synapses converging onto single interneurons of different types in the CA1 area of the rat hippocampus	10559416	10.1523/JNEUROSCI.19-22-10082.1999	Cited
Hanawa, H, Blood, 2004, Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus-based lentiviral vector system	14976042	10.1182/blood-2004-01-0045	Cited
Hansel, D et al., J Neurosci, 2012, The mechanism of orientation selectivity in primary visual cortex without a functional map	22442071	10.1523/JNEUROSCI.6284-11.2012	Cited
Hippenmeyer, S, PLoS Biol, 2005, A developmental switch in the response of DRG neurons to ETS transcription factor signaling	15836427	10.1371/journal.pbio.0030159	Cited
Hofer, SB, Nat Neurosci, 2011, Differential connectivity and response dynamics of excitatory and inhibitory neurons in visual cortex	21765421	10.1038/nn.2876	Cited
Horikawa, K, Nat Methods, 2010, Spontaneous network activity visualized by ultrasensitive Ca(2+) indicators, yellow Cameleon-Nano	20693999	10.1038/nmeth.1488	Cited
Huber, D, Nature, 2012, Multiple dynamic representations in the motor cortex during sensorimotor learning	22538608	10.1038/nature11039	Cited
Jia, H et al., Nature, 2010, Dendritic organization of sensory input to cortical neurons in vivo	20428163	10.1038/nature08947	Cited
Katona, G, Proc Natl Acad Sci USA, 2011, Roller Coaster Scanning reveals spontaneous triggering of dendritic spikes in CA1 interneurons	21224413	10.1073/pnas.1009270108	Cited
Kerlin, AM et al., Neuron, 2010, Broadly tuned response properties of diverse inhibitory neuron subtypes in mouse visual cortex	20826316	10.1016/j.neuron.2010.08.002	Cited
Kerr, R, Neuron, 2000, Optical imaging of calcium transients in neurons and pharyngeal muscle of C. elegans	10896155	10.1016/s0896-6273(00)81196-4	Cited
Ko, H, Nature, 2011, Functional specificity of local synaptic connections in neocortical networks	21478872	10.1038/nature09880	Cited
Kobat, D, Opt Express, 2009, Deep tissue multiphoton microscopy using longer wavelength excitation	19654740	10.1364/oe.17.013354	Cited
Kralj, JM et al., Nat Methods, 2012, Optical recording of action potentials in mammalian neurons using a microbial rhodopsin	22120467	10.1038/nmeth.1782	Cited
Liu, BH, Neuron, 2011, Broad inhibition sharpens orientation selectivity by expanding input dynamic range in mouse simple cells	21835349	10.1016/j.neuron.2011.06.017	Cited
Longair, MH et al., Bioinformatics, 2011, Simple Neurite Tracer: open source software for reconstruction, visualization and analysis of neuronal processes	21727141	10.1093/bioinformatics/btr390	Cited
Mainen, ZF et al., Nature, 1999, Synaptic calcium transients in single spines indicate that NMDA receptors are not saturated	10335844	10.1038/20187	Cited
Mank, M, Nat Methods, 2008, A genetically encoded calcium indicator for chronic in vivo two-photon imaging	19160515	10.1038/nmeth.1243	Cited
Mao, T et al., PloS One, 2008, Characterization and subcellular targeting of GCaMP-type genetically-encoded calcium indicators	18350138	10.1371/journal.pone.0001796	Cited
Miyawaki, A, Nature, 1997, Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin	9278050	10.1038/42264	Cited
Nagai, T et al., Proc Natl Acad Sci USA, 2004, Expanded dynamic range of fluorescent indicators for Ca2+ by circularly permuted yellow fluorescent proteins	15247428	10.1073/pnas.0400417101	Cited
Nakai, J et al., Nat Biotechnol, 2001, A high signal-to-noise Ca(2+) probe composed of a single green fluorescent protein	11175727	10.1038/84397	Cited
Niell, CM et al., J Neurosci, 2008, Highly selective receptive fields in mouse visual cortex	18650330	10.1523/JNEUROSCI.0623-08.2008	Cited
Ohki, K et al., Nature, 2005, Functional imaging with cellular resolution reveals precise micro-architecture in visual cortex	15660108	10.1038/nature03274	Cited
Palmer, AE, Chem Biol, 2006, Ca2+ Indicators Based on Computationally Redesigned Calmodulin-Peptide Pairs	16720273	10.1016/j.chembiol.2006.03.007	Cited
Pelli, DG, Spat Vis, 1997, The VideoToolbox software for visual psychophysics: transforming numbers into movies	9176953	—	Cited
Petreanu, L, Nature, 2012, Activity in motor-sensory projections reveals distributed coding in somatosensation	22922646	10.1038/nature11321	Cited
Pologruto, TA et al., Biomed Eng Online, 2003, ScanImage: Flexible software for operating laser-scanning microscopes	12801419	10.1186/1475-925X-2-13	Cited
Pologruto, TA et al., J Neurosci, 2004, Monitoring neural activity and [Ca2+] with genetically encoded Ca2+ indicators	15509744	10.1523/JNEUROSCI.2854-04.2004	Cited
Reiff, DF, J Neurosci, 2005, In vivo performance of genetically encoded indicators of neural activity in flies	15888652	10.1523/JNEUROSCI.4900-04.2005	Cited
Sabatini, BL et al., Neuron, 2002, The life cycle of Ca(2+) ions in dendritic spines	11832230	10.1016/s0896-6273(02)00573-1	Cited
Shaner, NC, Nat Biotechnol, 2004, Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein	15558047	10.1038/nbt1037	Cited
Sobczyk, A et al., J Neurosci, 2005, NMDA receptor subunit-dependent [Ca2+] signaling in individual hippocampal dendritic spines	15987933	10.1523/JNEUROSCI.1221-05.2005	Cited
Sohya, K et al., J Neurosci, 2007, GABAergic neurons are less selective to stimulus orientation than excitatory neurons in layer II/III of visual cortex, as revealed by in vivo functional Ca2+ imaging in transgenic mice	17314309	10.1523/JNEUROSCI.4641-06.2007	Cited
Stewart, SA, RNA, 2003, Lentivirus-delivered stable gene silencing by RNAi in primary cells	12649500	10.1261/rna.2192803	Cited
Suter, BA, Front Neural Circuits, 2010, Ephus: multipurpose data acquisition software for neuroscience experiments	21960959	10.3389/fncir.2010.00100	Cited
Svoboda, K et al., Nature, 1997, In vivo dendritic calcium dynamics in neocortical pyramidal neurons	8990119	10.1038/385161a0	Cited
Tan, AY et al., J Neurosci, 2011, Orientation selectivity of synaptic input to neurons in mouse and cat primary visual cortex	21865476	10.1523/JNEUROSCI.2039-11.2011	Cited
Tank, DW et al., Science, 1988, Spatially resolved calcium dynamics of mammalian Purkinje cells in cerebellar slice	2847315	10.1126/science.2847315	Cited
Thevenaz, P et al., IEEE Trans Image Process, 1998	18267377	10.1109/83.650848	Cited
Tian, L, Nat Methods, 2009, Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators	19898485	10.1038/nmeth.1398	Cited
Trachtenberg, JT, Nature, 2002, Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex	12490942	10.1038/nature01273	Cited
Wang, Q et al., Structure, 2008, Structural basis for calcium sensing by GCaMP2	19081058	10.1016/j.str.2008.10.008	Cited
Wang, Y, J Neurosci, 2004, Stereotyped odor-evoked activity in the mushroom body of Drosophila revealed by green fluorescent protein-based Ca2+ imaging	15269261	10.1523/JNEUROSCI.3727-03.2004	Cited
Xu, NL, Nature, 2012, Nonlinear dendritic integration of sensory and motor input during an active sensing task	23143335	10.1038/nature11601	Cited
Zariwala, HA, J Neurosci, 2012, A Cre-Dependent GCaMP3 Reporter Mouse for Neuronal Imaging In Vivo	22378886	10.1523/JNEUROSCI.4469-11.2012	Cited
Zhao, Y, Science, 2011, An expanded palette of genetically encoded Ca(2) indicators	21903779	10.1126/science.1208592	Cited

In this knowledge base

Title	Year	PMID
Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons.	2023	36207584

External

Title	Authors	Journal	Year	Link
Aberrant hypothalamic neuronal activity blunts glucocorticoid diurnal rhythms in murine breast cancer.	Gomez AM et al.	—	2026	→
Accumbal calcium-permeable AMPA receptors orchestrate neuronal ensembles underlying social attachment.	El-Kalliny MM et al.	—	2026	→
A chemogenetic approach for temporal and cell-specific activation of endogenous GPCRs in vivo.	Shingles G et al.	—	2026	→
Adaptive optical correction for in vivo two-photon fluorescence microscopy with neural fields.	Kang I et al.	—	2026	→
A forebrain hub for cautious actions via the midbrain.	Zhou J et al.	—	2026	→
A helper NLR channels organellar calcium to trigger plant immunity.	Ibrahim T et al.	—	2026	→
A Hidden Checkpoint: Bidirectional pH Remodeling of the Immunological Synapse in Cancer, Methods, and Therapeutic Opportunities.	Guillemette A et al.	—	2026	→
ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid-β Pathology.	Li Y et al.	—	2026	→
A mouse model for cerebral/cortical visual impairment (CVI) impairs vision and disrupts the spatial frequency tuning of neurons in visual cortex.	Oakes DK et al.	—	2026	→
A multicellular analysis calcium imaging toolbox for ImageJ.	Hageter J et al.	—	2026	→
Arabidopsis IONIC CURRENT FAMILY A proteins facilitate environmental calcium acquisition essential for stress tolerance.	Ren Z et al.	—	2026	→
Astrocyte Proximity Protects Synapses From Human Amyloid-Beta Induced Degeneration in a Mouse Ex Vivo Model of Early Alzheimer's Disease.	Gobbo F et al.	—	2026	→
A TRPV4-dependent calcium signaling axis regulates lamellipodial actin architecture to promote cell migration.	Iu E et al.	—	2026	→
Atypical social behaviors in mouse models for Rett syndrome.	Acevedo-Triana C et al.	—	2026	→
A voltage-dependent switch underlies efficient yet specific learning and memory.	Manoim Wolkovitz JE et al.	—	2026	→
Behavioral adaptation to warm conditions via Lim1-mediated acceleration of neuronal clocks.	Liu Z et al.	—	2026	→
BEST1-mediated tonic excitation facilitates anxiety-like behaviors in a mouse model of chronic neuropathic pain.	Xiong S et al.	—	2026	→
Birthdate aligns vestibular sensory neurons with central and motor partners across a sensorimotor reflex circuit for gaze stabilization.	Huang S et al.	—	2026	→
Bridging Model and Experiment in Systems Neuroscience with Cleo: The Closed-Loop, Electrophysiology, and Optophysiology Simulation Testbed.	Johnsen KA et al.	—	2026	→
CaBLAM: a high-contrast bioluminescent Ca<sup>2+</sup> indicator derived from an engineered Oplophorus gracilirostris luciferase.	Lambert GG et al.	—	2026	→
Calcium Imaging Studies in Enteric Glia.	Thomasi B et al.	—	2026	→
Cellular multipoint adaptive technology for two-photon mesoscope.	Chen S et al.	—	2026	→
Conflicting adaptations in an inhibitory feedback circuit.	Bergmann GA et al.	—	2026	→
Connectivity underlying motor cortex activity during goal-directed behaviour.	Finkelstein A et al.	—	2026	→
Decoding Spikes From Multiunit Data.	Farina D et al.	—	2026	→
Designer indicators for two-photon recording of subthreshold voltage dynamics.	Land MA et al.	—	2026	→
Disinhibition of ventral tegmental area during initial punishment learning causes enduring punishment insensitivity.	Tan SYS et al.	—	2026	→
Diverse Neuronal Activity in Barrel Cortex During Self-Grooming and Whisking in Mice.	Ge J et al.	—	2026	→
Dual roles of TRPV2 in the innate immune response to cytosolic DNA: Arresting dormant and boosting activated STING.	Cheng C et al.	—	2026	→
Duox-driven ROS release by glia promotes regeneration in the adult Drosophila brain.	Alves CS et al.	—	2026	→
Dynamic feedback control of oncogenic tyrosine kinase signaling in acute leukemia.	Lee J et al.	—	2026	→
Establishing functional giant Dictyostelium cells reveals front-rear polarity in intracellular signaling.	Hayashida Y et al.	—	2026	→
Evaluating linear model frameworks for directed predictive influence estimation from hypothalamic calcium imaging.	Clementsmith X et al.	—	2026	→
Fast and accessible morphology-free functional fluorescence imaging analysis.	Estrada Berlanga A et al.	—	2026	→
Fentanyl and alcohol co-exposure induce robust, sustained hyperlocomotion and neural circuit disruption in larval zebrafish.	Hillman C et al.	—	2026	→
Functional synaptic connectivity shapes spine stability in the hippocampus.	Rais C et al.	—	2026	→
Genetic mapping identifies Homer1 as a developmental modifier of attention.	Gershon Z et al.	—	2026	→
GIP receptor agonism suppresses inflammation-induced aversion and food intake via distinct circuits.	Province HS et al.	—	2026	→
Glutamate indicators with increased sensitivity and tailored deactivation rates.	Aggarwal A et al.	—	2026	→
High-fat food reinforces risk taking by suppressing defensive neurons.	de Araujo Salgado I et al.	—	2026	→
High-throughput assessment of vocal modulation following chemogenetic inhibition in songbirds.	Song C et al.	—	2026	→
Holographic transcranial ultrasound neuromodulation enhances stimulation efficacy by cooperatively recruiting distributed brain circuits.	Estrada H et al.	—	2026	→
Imaging Ca<sup>2+</sup> Signaling in Trypanosoma cruzi with Genetically Encoded Ca<sup>2+</sup> Indicators.	Huang G et al.	—	2026	→
Impairment of neuronal activity occurs at the early stages of the aggregation cascade of Aβ1-42 and mutant Tau.	Hirsch F et al.	—	2026	→
Injury-induced electrochemical coupling triggers organ growth.	Liu J et al.	—	2026	→
Insulin and leucokinin pathways coordinate adaptive salt appetite in <i>Drosophila</i>.	Puri S et al.	—	2026	→
Intrinsic Diversity in Odor-Evoked Calcium Rises across <i>Drosophila</i> Olfactory Neurons.	Xiao 肖奕艺 Y et al.	—	2026	→
In vitro modeling of human dorsal root ganglion neurons for GCaMP6-based calcium imaging of sensory responses to HSV-1 infection.	Chen YC et al.	—	2026	→
In vitro vascularization improves in vivo functionality of human engineered cardiac tissues.	Li H et al.	—	2026	→
In vivo multimodal neurochemical interfaces for real-time decoding of brain circuit.	Kim Y et al.	—	2026	→
Long-term editing of brain circuits using an engineered electrical synapse.	Ransey E et al.	—	2026	→
Loss of B3GAT1/HNK-1 disrupts glioma-CD8<sup>+</sup> T cell immune synapse formation for immune escape.	Duan J et al.	—	2026	→
<i>In Cellulo</i> Fabrication of Supramolecular Protein Assemblies.	Yang H et al.	—	2026	→
Medial prefrontal Cortex, dopamine and glutamate modulation in regulating Reward-Seeking and frustration responses.	de Oliveira Lima CA et al.	—	2026	→
Mitochondrial Ca<sup>2+</sup> efflux controls neuronal metabolism and long-term memory across species.	Amrapali Vishwanath A et al.	—	2026	→
Modelling chemotaxis of branched cells in complex environments provides insights into immune cell navigation.	Liu J et al.	—	2026	→
Movie reconstruction from mouse visual cortex activity.	Bauer J et al.	—	2026	→
Neural circuits for decision-making based on pineal photoreception in zebrafish.	Wada S et al.	—	2026	→
Next-generation multicolor indicators for in vivo imaging of norepinephrine.	Rohner VL et al.	—	2026	→
Noise Sources and Strategies for Signal Quality Improvement in Biological Imaging: A Review Focused on Calcium and Cell Membrane Voltage Imaging.	Nikolaev DM et al.	—	2026	→
Norepinephrine acts through radial astrocytes in the developing optic tectum to enhance threat detection and escape behavior.	Benfey NJ et al.	—	2026	→
Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry.	Dereddi RR et al.	—	2026	→
Optoelectronic Interfaces for Nongenetic Modulation of Excitable Tissues.	Wang Q et al.	—	2026	→
Optogenetic activation of primary sensory neurons induces metamorphosis in Ciona.	Totsuka NM et al.	—	2026	→
OPTRACE: Optical Imaging-Guided Transplantation and Tracking of Cells in the Mouse Brain.	Wang J et al.	—	2026	→
Pancreatic islet cell calcium ion imaging at single-cell resolution: functional identification of first-responder, highly connected ("hub"), and leader beta-cells.	Delgadillo-Silva LF et al.	—	2026	→
Parallel Morphological and Functional Development in the Xenopus Retinotectal System.	Li VJ et al.	—	2026	→
Parvalbumin neurons in inferior colliculus mediate maladaptive inhibitory compensation in age-related hearing loss.	Luo Y et al.	—	2026	→
PinkyCaMP: an mScarlet-based calcium sensor with enhanced brightness, photostability and multiplexing capabilities.	Fink R et al.	—	2026	→
Place cells in CA1 lack topographical organization of firing locations.	Slettmoen T et al.	—	2026	→
Place field dynamics in retrosplenial cortex compared to hippocampus.	Navratilova Z et al.	—	2026	→
Plastic landmark anchoring in zebrafish compass neurons.	Tanaka R et al.	—	2026	→
Portable geosmin detection system based on sensor cells expressing insect odorant receptors.	Mitsuno H et al.	—	2026	→
Position-independent emergence of neocortical neuron molecular identity, connectivity and function.	Roig-Puiggros S et al.	—	2026	→
Potentiation of active locomotor state by spinal-projecting serotonergic neurons.	Fenstermacher SJ et al.	—	2026	→
Reliable Inference of the Encoding of Task States by Individual Neurons Using Calcium Imaging.	Huang H et al.	—	2026	→
Resolving synaptic events using subsynaptically targeted GCaMP8 variants.	Chen J et al.	—	2026	→
Selective weakening of population-coupled synaptic activity in vivo in a mouse model of amyloid-beta pathology.	Melgosa-Ecenarro L et al.	—	2026	→
Sleep facilitates pattern separation through SK channel-mediated sparse coding.	Chen CC et al.	—	2026	→
Social valence dictates sex differences in identity recognition.	Larosa A et al.	—	2026	→
Spontaneous behavior is a succession of self-directed tasks.	Weinreb C et al.	—	2026	→
Subcellular calcium dynamics and organelle perturbations in resistosome-mediated cell death.	Chen YF et al.	—	2026	→
Subfamily I ethylene receptors are functionally conserved in calcium permeability across the green lineage.	Yu D et al.	—	2026	→
Synthetic multicolor antigen-stabilizable nanobody platform for intersectional labeling and functional imaging.	Barykina NV et al.	—	2026	→
The dentate gyrus efficiently converges LEC and MEC inputs into multimodal, highly specific and reliable environmental representations.	Cholvin T et al.	—	2026	→
The Geometry of Layer 2/3 Cortical Sound Processing in Slow Wave Sleep.	Muller A et al.	—	2026	→
The regenerative period of somatosensory nerves is closed by a DCC signaling axis.	Hammer J et al.	—	2026	→
The representation of omitted sounds in the mouse auditory cortex.	Peters J et al.	—	2026	→
To see and to know: the power of live imaging in illuminating and decoding biological complexity.	Yang M et al.	—	2026	→
Unlocking neuronal health: leveraging C. elegans for drug repurposing studies.	Gowda S et al.	—	2026	→
Vesicular Glutamate Release Is Necessary for Neural Tube Formation.	Goyal R et al.	—	2026	→
Visual information is broadcast among cortical areas in discrete channels.	Yu Y et al.	—	2026	→
Voltage imaging as a window into neural computation.	Keijser J et al.	—	2026	→
Vulnerability of short-term memory in a mouse model of Alzheimer's disease.	Li C et al.	—	2026	→
ABA-activated low-nanomolar Ca<sup>2+</sup>-CPK signalling controls root cap cycle plasticity and stress adaptation.	Lin Z et al.	—	2025	→
Aberration correction in long GRIN lens-based microendoscopes for extended field-of-view two-photon imaging in deep brain regions.	Sattin A et al.	—	2025	→
A cell-type-specific epigenetic mechanism encodes social investigatory behavior via Lrhcn1 and Hcn1.	Qin P et al.	—	2025	→
A column-like organization for ocular dominance in mouse visual cortex.	Goltstein PM et al.	—	2025	→
A competitive disinhibitory network for robust optic flow processing in Drosophila.	Erginkaya M et al.	—	2025	→
A contextual fear conditioning paradigm in head-fixed mice exploring virtual reality.	Krishnan S et al.	—	2025	→
Activation of ionotropic and group I metabotropic glutamate receptors stimulates kisspeptin neuron activity in mice.	Bearss RJ et al.	—	2025	→
Activity-induced conversion from dendritic filopodia to spines mediated by NMDA receptor-dependent calcium transients and vesicular exocytosis.	Liu HJ et al.	—	2025	→
Acute and circadian feedforward regulation of agouti-related peptide hunger neurons.	Douglass AM et al.	—	2025	→
A detailed protocol for sparse and bright labeling of neurons via dual adeno-associated virus vectors with Cre recombination.	Takahashi M et al.	—	2025	→
Advances in two-photon imaging for monitoring neural activity in behaving mice.	Li R et al.	—	2025	→
A food-sensitive olfactory circuit drives anticipatory satiety.	Bulk J et al.	—	2025	→
A Genetically Encoded Fluorescent Biosensor for Intracellular Measurement of Malonyl-CoA.	Ranzau BL et al.	—	2025	→
A genetically encoded secreted toxin potentiates synaptic NMDA receptors in hippocampal neurons and confers neuroprotection.	Carmi I et al.	—	2025	→
Aging disrupts the link between network centrality and functional properties of prefrontal neurons during memory-guided behavior.	Ranjbar-Slamloo Y et al.	—	2025	→
A green lifetime biosensor for calcium that remains bright over its full dynamic range.	van der Linden FH et al.	—	2025	→
AI-Powered Mice Behavior Tracking and Its Application for Neuronal Manifold Analysis Based on Hippocampal Ensemble Activity in an Alzheimer's Disease Mice Model.	Gerasimov E et al.	—	2025	→
All active hippocampal pyramidal cells are place cells.	Talpir I et al.	—	2025	→
Alleviating head-mounted weight burden for neural imaging in freely-behaving rodents.	Liu Y et al.	—	2025	→
Altered Neural Activity in the Mesoaccumbens Pathway Underlies Impaired Social Reward Processing in Shank3-Deficient Rats.	Barbier M et al.	—	2025	→
Aminergic and peptidergic modulation of insulin-producing cells in <i>Drosophila</i>.	Held M et al.	—	2025	→
A model of ethanol self-administration in head-fixed mice.	Ward AL et al.	—	2025	→
Amyloid-β-induced alteration of fast and localized calcium elevations in cultured astrocytes.	Nakata K et al.	—	2025	→
An accurate and sensitive method for neurotoxicity assessment of emerging contaminants in zebrafish.	Su M et al.	—	2025	→
Analysis of neuronal activity impairment in iPSC-derived neurons from idiopathic autism patients.	Kern A et al.	—	2025	→
An Enhanced Red Bioluminescent Indicator for Responsive Detection of Physiological Calcium Dynamics in Cells and Mice.	Tian X et al.	—	2025	→
An essential experimental control for functional connectivity mapping with optogenetics.	Tadres D et al.	—	2025	→
A neural correlate of individual odor preference in <i>Drosophila</i>.	Churgin MA et al.	—	2025	→
A neural manifold view of the brain.	Perich MG et al.	—	2025	→
A neural mechanism for learning from delayed postingestive feedback.	Zimmerman CA et al.	—	2025	→
An extension module for a two-photon microscope enables flexible <i>in vivo</i> imaging and all-optical physiology.	Takeuchi RF et al.	—	2025	→
An improved FLARE system for recording and manipulating neuronal activity.	Zhou G et al.	—	2025	→
An integrated microfluidic and fluorescence platform for probing in vivo neuropharmacology.	Piantadosi SC et al.	—	2025	→
Annexin A6 membrane repair protein protects against amyloid-induced dystrophic neurites and tau phosphorylation in Alzheimer's disease model mice.	Sadleir KR et al.	—	2025	→
A novel protein for bioremediation of gadolinium waste.	Lee HD et al.	—	2025	→
A parabrachial hub for need-state control of enduring pain.	Goldstein N et al.	—	2025	→
A pontine center in descending pain control.	Li T et al.	—	2025	→
A Positive Allosteric Modulator of the SERCA Pump Rescues Hippocampal Neuronal Circuits Dysfunction and Cognitive Defects in a Mouse Model of Alzheimer's Disease.	Gerasimov E et al.	—	2025	→
A positive allosteric modulator of α7 nicotinic receptor reduces levodopa-induced dyskinesias in hemi-parkinsonian mice.	Gómez-Paz A et al.	—	2025	→
A Preprocessing Toolbox for 2-Photon Subcellular Calcium Imaging.	Jiang A et al.	—	2025	→
A real-time all-optical interface for dynamic perturbation of neural activity during behavior.	Zhang Z et al.	—	2025	→
A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular L-lactate dynamics.	Kamijo Y et al.	—	2025	→
Artificial embodied circuits uncover neural architectures of vertebrate visuomotor behaviors.	Liu X et al.	—	2025	→
A sensitive soma-localized red fluorescent calcium indicator for in vivo imaging of neuronal populations at single-cell resolution.	Zhou S et al.	—	2025	→
A septo-hypothalamic-medullary circuit directs stress-induced analgesia.	Shah DP et al.	—	2025	→
A soft multimodal optoelectronic array interface for multiparametric mapping of heart function in vivo.	Quirion NT et al.	—	2025	→
A spherical code of retinal orientation selectivity enables decoding in ensembled and retinotopic operation.	Laniado DD et al.	—	2025	→
Astrocytes in the External Globus Pallidus Selectively Represent Routine Formation During Repeated Reward-Seeking in Mice.	Yang MA et al.	—	2025	→
Astrocytic BEST1 can serve as a target for functional recovery after ischemic stroke.	Xiong S et al.	—	2025	→
Asymmetric activation of retinal ON and OFF pathways by AOSLO raster-scanned visual stimuli.	Patterson SS et al.	—	2025	→
A time window for memory consolidation during NREM sleep revealed by cAMP oscillation.	Deng Z et al.	—	2025	→
Atypical plume-like events contribute to glutamate accumulation in metabolic stress conditions.	Ziebarth T et al.	—	2025	→
Autism-associated <i>Scn2a</i> haploinsufficiency disrupts in vivo dendritic signaling and impairs flexible decision-making.	Wu H et al.	—	2025	→
Automated cell annotation in multi-cell images using an improved CRF_ID algorithm.	Lee HJ et al.	—	2025	→
Avian bioresources for developmental biology: Chicken and quail resources in the United Kingdom, France, and Japan.	Henderson L et al.	—	2025	→
Axonal correlates of striatal calcium transients measured by fiber photometry.	Lipton DM et al.	—	2025	→
Biocompatible EDOT-Pyrrole Conjugated Conductive Polymer Coating for Augmenting Cell Attachment, Activity, and Differentiation.	Muzzio N et al.	—	2025	→
Bioelectrosynthesis of Signaling Molecules for Selective Modulation of Cell Signaling.	Lee M et al.	—	2025	→
Bitter Sensing Protects <i>Drosophila</i> from Developing Experience-Dependent Cocaine Consumption Preference.	Philyaw TJ et al.	—	2025	→
Brain region-specific gain modulation of place cells by VIP neurons.	Lenkey N et al.	—	2025	→
Brain-Wide Impacts of Sedation on Spontaneous Activity and Auditory Processing in Larval Zebrafish.	Favre-Bulle IA et al.	—	2025	→
Brain-wide microstrokes affect the stability of memory circuits in the hippocampus.	Heiser H et al.	—	2025	→
Bridging the gap: umIT makes complex imaging data accessible to scientists of all backgrounds.	Ferreira de Souza BO et al.	—	2025	→
Calcium Dynamics in Astrocyte-Neuron Communication from Intracellular to Extracellular Signaling.	Nowacka A et al.	—	2025	→
Calcium Dynamics in Hypothalamic Paraventricular Oxytocin Neurons and Astrocytes Associated with Social and Stress Stimuli.	Sandoval KC et al.	—	2025	→
Calcium Imaging in Vivo: How to Correctly Select and Apply Fiber Optic Photometric Indicators.	Wu L et al.	—	2025	→
Calcium imaging of central amygdala activity after escalation of fentanyl self-administration.	Malone SG et al.	—	2025	→
Calcium imaging: Unraveling the neurobiological mechanisms of depression across cellular and circuit dimensions.	Han X et al.	—	2025	→
Calcium signaling is required for anterior patterning in the mouse embryo.	Stower MJ et al.	—	2025	→
Calcium transfer from the ER to other organelles for optimal signaling in <i>Toxoplasma gondii</i>.	Li ZH et al.	—	2025	→
Cannabinoid CB<sub>1</sub> Receptor Activation Mitigates <i>N</i>‑Methyl‑d‑aspartate Receptor-Mediated Neurotoxicity.	Navarro G et al.	—	2025	→
CB2R-cAMP-Epac1 pathway orchestrates epithelial-neural-immune interactions in atopic dermatitis.	Hu X et al.	—	2025	→
Cell type-specific contributions to a persistent aggressive internal state in female <i>Drosophila</i>.	Chiu H et al.	—	2025	→
Cellular characterization of the mouse collecting lymphatic vessels reveals that lymphatic muscle cells are the innate pacemaker cells.	Zawieja SD et al.	—	2025	→
Characterization of adeno-associated viral transduction of retinal ganglion cells in adult and old mice.	Henderson DC et al.	—	2025	→
Characterization of depth perception information inferred from neuronal activity in primary visual cortex.	Dong N et al.	—	2025	→
Chemical imaging for biological systems: techniques, AI-driven processing, and applications.	Cui Y et al.	—	2025	→
Chemogenetic activation of Gq signaling modulates dendritic development of cortical neurons in a time- and layer-specific manner.	Köhler I et al.	—	2025	→
Cholinergic regulation of osteocyte mechanobiology: A paradigm for bone adaptation.	Mora-Antoinette M et al.	—	2025	→
Chronic in vivo sequelae of repetitive acute mfb-DBS on accumbal dopamine and midbrain neuronal activity.	Miguel Telega L et al.	—	2025	→
Circuit Reorganization of Subicular Cell-Type-Specific Interneurons in Temporal Lobe Epilepsy.	Fei F et al.	—	2025	→
Closed-loop two-photon functional imaging in a freely moving animal.	McNulty P et al.	—	2025	→
Compact module for video-rate image mosaics in two-photon microscopy.	Quirin S	—	2025	→
Complement-independent pathogenic influences of anti-HMGCR + and anti-SRP + immune-mediated necrotizing myopathy autoantibodies on engineered muscle function.	Lad H et al.	—	2025	→
Comprehensive insights into glioblastoma multiforme: drug delivery challenges and multimodal treatment strategies.	Dhiman A et al.	—	2025	→
Compressive streak microscopy for fast sampling of fluorescent reporters of neural activity.	Cai C et al.	—	2025	→
Connexin hemichannel blockade by abEC1.1 disrupts glioblastoma progression, suppresses invasiveness, and reduces hyperexcitability in preclinical models.	Donati V et al.	—	2025	→
Contralesional hippocampal spreading depolarization promotes functional recovery after stroke.	Boyce AKJ et al.	—	2025	→
Coordination of distinct sources of excitatory inputs enhances motion selectivity in the mouse visual thalamus.	Fei Y et al.	—	2025	→
Cortical versus hippocampal network dysfunction in a human brain assembloid model of epilepsy and intellectual disability.	McCrimmon CM et al.	—	2025	→
CpG-ODN from Streptococcus thermophilus as a tool for inducing extrinsic apoptosis via caspase-8 activation in mouse splenocytes.	Chowdhury MR et al.	—	2025	→
Decoding Molecular Network Dynamics in Cells: Advances in Multiplexed Live Imaging of Fluorescent Biosensors.	Chen Q et al.	—	2025	→
DeepInMiniscope: Deep learning-powered physics-informed integrated miniscope.	Tian F et al.	—	2025	→
Delayed integration of somatostatin interneurons into visual circuits.	Wang A et al.	—	2025	→
Dendritic growth and synaptic organization from activity-independent cues and local activity-dependent plasticity.	Kirchner JH et al.	—	2025	→
Dependence of mitochondrial calcium signalling and dynamics on the disaggregase, CLPB.	D'Angelo D et al.	—	2025	→
Developmental maturation of millimeter-scale functional networks across brain areas.	Powell NJ et al.	—	2025	→
Development and characterization of a scalable calcium imaging assay using human iPSC-derived neurons.	Haustein MD et al.	—	2025	→
Development of a submillimeter resolution PET scanner with compact geometry for hybrid multi-photon/PET imaging.	Kang HG et al.	—	2025	→
Development of coherent cortical responses reflects increased discriminability of feedforward inputs and their alignment with recurrent circuits.	Lempel AA et al.	—	2025	→
Dietary availability acutely influences puberty onset via a hypothalamic neural circuit.	Goto T et al.	—	2025	→
Differential dopaminergic modulation of the antennal lobe of Drosophila melanogaster.	Avishai G et al.	—	2025	→
Differential synaptic depression mediates the therapeutic effect of deep brain stimulation.	Li J et al.	—	2025	→
Direct photoreception by pituitary endocrine cells regulates hormone release and pigmentation.	Fukuda A et al.	—	2025	→
Discovery and Treatment of Action Potential-Independent Myotonia in Hyperkalemic Periodic Paralysis.	Dupont C et al.	—	2025	→
Discretized representations in V1 predict suboptimal orientation discrimination.	Corbo J et al.	—	2025	→
Dissociable cortical contributions to impulse control during waiting.	Hao MHZ et al.	—	2025	→
Distinct circuit motifs evaluate opposing innate values of odors.	Someya M et al.	—	2025	→
Distinct dendritic integration strategies control dynamics of inhibition in the neocortex.	Morabito A et al.	—	2025	→
Distinctive regional patterns of dynamic neural noise in cortical activity.	Scarciglia A et al.	—	2025	→
Dopamine activity encodes the changing valence of the same stimulus in conditioned taste aversion paradigms.	Loh MK et al.	—	2025	→
Dynamic changes in cortical neurotrophic factor-positive interneurons during sleep.	Muheim CM et al.	—	2025	→
Dynamic Changes in Hindlimb Motor Cortex Neurons during Simulated Weightlessness Revealed by Miniature 2-Photon Microscopy.	Fan Y et al.	—	2025	→
Dysfunction of cortical GABAergic projection neurons as a major hallmark in a model of neuropsychiatric syndrome.	Asenjo-Martinez A et al.	—	2025	→
ECoGScope: An integrated platform for real-time Electrophysiology and fluorescence imaging.	Eun J et al.	—	2025	→
Ectopic sodium channel expression decreases excitability of Drosophila Kenyon cells.	Greenin-Whitehead K et al.	—	2025	→
Editorial: Methods in cellular neurobiology research.	Han S et al.	—	2025	→
Editorial: Signaling pathways and brain circuitry underlying circadian rhythms and sleep.	Aten S et al.	—	2025	→
Effect of antidepressants and social defeat stress on the activity of dorsal raphe serotonin neurons in free-moving animals.	Koda M et al.	—	2025	→
Effects of Light and Water Agitation on Hatching Processes in False Clownfish Amphiprion ocellaris.	Yamanaka S et al.	—	2025	→
Electroacupuncture reduces visceral pain and anxiety associated with inflammatory bowel disease by inhibition of vHPC-to-mPFC pathway.	Hu XF et al.	—	2025	→
Emergence of a brainstem somatosensory tonotopic map for substrate vibration.	Lee KS et al.	—	2025	→
Engineering of Genetically Encoded Bright Near-Infrared Fluorescent Voltage Indicator.	Xiao X et al.	—	2025	→
Enhancement of hippocampal interneuron excitability by NMDA receptor positive allosteric modulation.	Xing H et al.	—	2025	→
Environmental caffeine triggers oxidative stress and behavioral changes in Cyprinus carpio: Insights into neurotoxicity.	Casas-Hinojosa I et al.	—	2025	→
Erasable hippocampal neural signatures predict memory discrimination.	Kinsky NR et al.	—	2025	→
Evidence for Auditory Stimulus-Specific Adaptation But Not Deviance Detection in Larval Zebrafish Brains.	Wilde M et al.	—	2025	→
Exposure to COVID-19 virus-like particles modulates firing patterns of cortical neurons in the mouse brain.	Das A et al.	—	2025	→
Extinction and subsequent updating of innate fear responses to a visual looming stimulus rely on hippocampus-dependent mechanisms.	Conway PB et al.	—	2025	→
Ex vivo calcium imaging of sympathetic neurons in intact mouse stellate ganglia.	Scalco A et al.	—	2025	→
FACED 2.0 enables large-scale voltage and calcium imaging <i>in vivo</i>	Zhong J et al.	—	2025	—
FACED 2.0 enables large-scale voltage and calcium imaging in vivo.	Zhong J et al.	—	2025	→
Far-red fluorescent genetically encoded calcium ion indicators.	Dalangin R et al.	—	2025	→
Feeding-induced olfactory cortex suppression reduces satiation.	Lo H et al.	—	2025	→
Fibrillin-Related Proteins Control Calcium Homeostasis in Dystrophic Muscle Across Species.	Marchiafava D et al.	—	2025	→
Flow-sensitive ion channels in vascular endothelial cells: Mechanisms of activation and roles in mechanotransduction.	Beverley KM et al.	—	2025	→
Fluorescent sensors for intracellular signaling in the brain: imaging neurons, glia, and vascular cells.	Kim M et al.	—	2025	→
Four individually identified paired dopamine neurons signal taste punishment in larval <i>Drosophila</i>.	Weber D et al.	—	2025	→
Functional dissection of a neuronal brain circuit mediating higher-order associative learning.	Rachad EY et al.	—	2025	→
Functional specialisation of multisensory temporal integration in the mouse superior colliculus.	Bianchini G et al.	—	2025	→
Fundamentals of Gas-Free Calibrated fMRI for Oxidative Metabolic Neuroimaging.	Hyder F et al.	—	2025	→
Generation of stable brain cell cultures from embryonic zebrafish to interrogate phenotypes in zebrafish mutants of neurodevelopmental disorders.	Odierna GL et al.	—	2025	→
Genetically encoded fluorogenic RNA-based bioluminescence resonance energy transfer (BRET) sensors for cellular imaging and target detection.	Mi L et al.	—	2025	→
Genetically encoded sensors illuminate <i>in vivo</i> detection for neurotransmission: Development, application, and optimization strategies.	Zhong X et al.	—	2025	→
Heterogeneous plasticity of amygdala interneurons in associative learning and extinction.	Favila N et al.	—	2025	→
Higher-order thalamic input to cortex selectively conveys state information.	Neske GT et al.	—	2025	→
Highly dynamic and sensitive NEMOer calcium indicators for imaging ER calcium signals in excitable cells.	Gu W et al.	—	2025	→
Highly sensitive in vivo detection of dynamic changes in enkephalins following acute stress in mice.	Mikati MO et al.	—	2025	→
High-resolution imaging reveals a cascade of interconnected cellular bioeffects differentiating the long-term fates of sonoporated cells.	Lee JLF et al.	—	2025	→
High-speed neural imaging with multiplexed miniaturized two-photon microscopy.	Zhang Z et al.	—	2025	→
Hippocampus shapes entorhinal cortical output through a direct feedback circuit.	Butola T et al.	—	2025	→
HIV-1 Tat protein alters medial prefrontal cortex neuronal activity and recognition memory.	Yadav-Samudrala BJ et al.	—	2025	→
Homeostasis of a representational map in the neocortex.	Noda T et al.	—	2025	→
Human induced pluripotent stem cell-derived cardiomyocytes and their use in a cardiac organ-on-a-chip to assay electrophysiology, calcium and contractility.	Garcia MI et al.	—	2025	→
Hyperosmotic stimuli activate polycystin proteins to aid in urine concentration.	Márquez-Nogueras KM et al.	—	2025	→
Identification of two odorant receptors tuned to alarm pheromone compounds in the honey bee Apis mellifera.	Andreu B et al.	—	2025	→
Illuminating calcium and potassium dynamics with red fluorescent sensors.	Geng L et al.	—	2025	→
<i>Lycium barbaru</i>m glycopeptide ameliorates aberrant neuronal activity via ER stress modulation in ventral forebrain organoids derived from depressive patients.	Tao MD et al.	—	2025	→
Imaging Electrical Activity of Retinal Ganglion Cells with Fluorescent Voltage and Calcium Indicator Proteins in Retinal Degenerative <i>rd1</i> Blind Mice.	Jung Y et al.	—	2025	→
Imaging Neural Activity in Intact, Semirestrained <i>Drosophila</i> Larvae.	Vasudevan D et al.	—	2025	→
Imaging neuronal voltage beyond the scattering limit.	Chen TW et al.	—	2025	→
Imaging probes for the detection of brain microenvironment.	Zhang S et al.	—	2025	→
Imaging sensory transmission and neuronal plasticity in primary sensory neurons with a positively tuned voltage indicator.	Zhang Y et al.	—	2025	→
Inferring neural population codes for <i>Drosophila</i> acoustic communication.	Pang R et al.	—	2025	→
Infralimbic parvalbumin neural activity facilitates cued threat avoidance.	Ho YY et al.	—	2025	→
Inhibiting astrocyte calcium dynamics terminates status epilepticus via wireless septal stimulation.	Tian C et al.	—	2025	→
Inhibitory circuit motifs in Drosophila larvae generate motor program diversity and variability.	Francis J et al.	—	2025	→
In Situ Plant Sensors: Toward Real-Time, High-Resolution Monitoring.	He T et al.	—	2025	→
Integrating optical neuroscience tools into touchscreen operant systems.	Piantadosi PT et al.	—	2025	→
Integrating reproductive states and social cues in the control of sociosexual behaviors.	Wang Y et al.	—	2025	→
Intracellular calcium imaging for agonist screening.	Wang H et al.	—	2025	→
Intrinsic electrical activity drives small-cell lung cancer progression.	Peinado P et al.	—	2025	→
In vivo imaging analyses to explore the integration of multimodal aversive sensory information in the central amygdala.	Zhou X et al.	—	2025	→
IP3R2-Mediated Astrocytic Ca<sup>2+</sup> Transients Are Critical to Sustain Modulatory Effects of Locomotion on Neurons in Mouse Somatosensory Cortex.	Fernández de la Puebla M et al.	—	2025	→
JNK signaling coordinates epithelial cell turnover through exocytosis in <i>Drosophila</i> ribosomal protein mutants.	Akai N et al.	—	2025	→
Kilohertz electrical stimulation evokes robust cellular responses like conventional frequencies but distinct population dynamics.	Ravasio CR et al.	—	2025	→
Large field-of-view volumetric deep brain imaging through gradient-index lenses.	Cheng Z et al.	—	2025	→
Large-scale synaptic dynamics drive the reconstruction of binocular circuits in mouse visual cortex.	Tsimring K et al.	—	2025	→
Laser microsurgery for presynaptic interrogation.	Wong HH et al.	—	2025	→
Layer-specific changes in sensory cortex across the lifespan in mice and humans.	Liu P et al.	—	2025	→
Lessons from the use of in vivo cellular calcium imaging in primary sensory neurons and spinal cord.	Shannonhouse J et al.	—	2025	→
Leveraging Fiber Photometry to Decipher Neural Circuits Underlying Anxiety in Mice.	Abdennebi SR et al.	—	2025	→
Levodopa Disrupts Activity Patterns and Encoding of Movement in Striatal Cholinergic Interneurons of Behaving Mice.	Atamna Y et al.	—	2025	→
Ligand-Independent Spontaneous Activation of Purinergic P2Y<sub>6</sub> Receptor Under Cell Culture Soft Substrate.	Nishimura A et al.	—	2025	→
Local Differences in Network Organization in the Auditory and Parietal Cortex, Revealed with Single Neuron Activation.	Khoury CF et al.	—	2025	→
Long-chain unsaturated free fatty acids control gut motility via nitrergic ganglia of the enteric nervous system.	Zhang JH et al.	—	2025	→
Longitudinal calcium imaging of BNST neurons in mice during optogenetic manipulation of paraventricular thalamus axon terminals.	Mindaye SA et al.	—	2025	→
Long-lasting, subtype-specific regulation of somatostatin interneurons during sensory learning.	Mosso MB et al.	—	2025	→
Lysosome and plasma membrane Piezo channels of Trypanosoma cruzi are essential for proliferation, differentiation and infectivity.	Huang G et al.	—	2025	→
Machine learning enables high-throughput, low-replicate screening for novel anti-seizure targets and compounds using combined movement and calcium fluorescence in larval zebrafish.	McGraw CM et al.	—	2025	→
Machine learning identification of enhancers in the rhesus macaque genome.	He J et al.	—	2025	→
Magnetoelectric nanodiscs enable wireless transgene-free neuromodulation.	Kim YJ et al.	—	2025	→
Mapping Synaptic Activity at the Population and Cellular Levels with Genetically Encoded Voltage Indicators (GEVIs).	Jung Y et al.	—	2025	→
Mating status-dependent dopaminergic modulation of auditory sensory neurons in <i>Drosophila</i>.	Yamakoshi H et al.	—	2025	→
Mechanical Modulation, Physiological Roles, and Imaging Innovations of Intercellular Calcium Waves in Living Systems.	Mackey C et al.	—	2025	→
Methods for Imaging Intracellular Calcium Signals in the Mouse Mammary Epithelium in Two and Three Dimensions.	Folacci M et al.	—	2025	→
Methods to Determine Lysosomal AMPK Activation.	Zhang CS et al.	—	2025	→
Microendoscopic calcium imaging in motor cortices of macaques during rest and movement.	Martel AC et al.	—	2025	→
Microfluidic platforms for monitoring cardiomyocyte electromechanical activity.	Wang W et al.	—	2025	→
Minimally invasive, wide-field two-photon imaging of the brainstem at cellular resolution.	Agetsuma M et al.	—	2025	→
Miniscope Imaging of Nucleus Accumbens Neural Activity in Freely Behaving Rats: Virus Injection, Gradient Index Lens Implantation, Recording Strategies, and Analytical Methods.	Beacher NJ et al.	—	2025	→
MiniXL: An open-source, large field-of-view epifluorescence miniscope enabling single-cell resolution and multi-region imaging in mice.	Zhao P et al.	—	2025	→
Mitochondrial Ca<sup>2+</sup> uniporter haploinsufficiency leads to sexually dimorphic redox imbalance and metabolic remodelling in the mouse brain.	Gray J et al.	—	2025	→
Modulating Amyloid Pathology-Neural Hyperexcitability Crosstalk for Alzheimer's Disease Therapy.	Wang Y et al.	—	2025	→
Motor learning refines thalamic influence on motor cortex.	Ramot A et al.	—	2025	→
Mrgprb4-lineage neurons indispensable in pressure induced pleasant sensation are polymodal.	Du L et al.	—	2025	→
MSL10 is a high-sensitivity mechanosensor in the tactile sense of the Venus flytrap.	Suda H et al.	—	2025	→
Multifaceted role of galanin in brain excitability.	Rieser NN et al.	—	2025	→
Multimodal dataset linking wide-field calcium imaging to behavior changes in operant lever-pull task in mice.	Kondo M et al.	—	2025	→
Multimodal identification of the mouse brain using simultaneous Ca<sup>2+</sup> imaging and fMRI.	Mandino F et al.	—	2025	→
Multiple mechanisms of action for an extremely painful venom.	Borjon LJ et al.	—	2025	→
Nanogold-albumin conjugates: transformative approaches for next-generation cancer therapy and diagnostics.	Jaiswal N et al.	—	2025	→
Neural circuit mechanisms for steering control in walking <i>Drosophila</i>.	Rayshubskiy A et al.	—	2025	→
Neural circuits underlying divergent visuomotor strategies of zebrafish and Danionella cerebrum.	Fouke KE et al.	—	2025	→
Neural mechanism of trigeminal nerve stimulation recovering defensive arousal responses in traumatic brain injury.	Zhang Q et al.	—	2025	→
Neural representation of self-initiated locomotion in the secondary motor cortex of mice across different environmental contexts.	Sun G et al.	—	2025	→
Neural signature of chronic migraine mice model and related photophobia in the primary visual cortex.	Zhang KB et al.	—	2025	→
Neural stem cell quiescence and activation dynamics are regulated by feedback input from their progeny under homeostatic and regenerative conditions.	Marymonchyk A et al.	—	2025	→
Neurodevelopmental origins of structural and psychomotor defects in CXCR4-linked primary immunodeficiency.	Demenego G et al.	—	2025	→
Neuronal deterioration associated with hyperexcitability under mild chronic cerebral hypoperfusion.	Urushihata T et al.	—	2025	→
Neuron-astrocyte coupling in lateral habenula mediates depressive-like behaviors.	Xin Q et al.	—	2025	→
New mechanistic understanding of FXR agonist Vonafexor: inducing sublethal damage of HBV-positive liver cancer cells via promoting anti-tumor immunity.	Pan B et al.	—	2025	→
Nitrous oxide activates layer 5 prefrontal neurons via SK2 channel inhibition for antidepressant effect.	Cichon J et al.	—	2025	→
Non-contact confocal calcium imaging of <i>in vivo</i> murine corneal nerves.	McPheeters MT et al.	—	2025	→
Nonlinear high-activity neuronal excitation enhances odor discrimination.	Manoim-Wolkovitz JE et al.	—	2025	→
Nonlinear integration of sensory inputs and behavioral state by a single neuron in C. elegans.	Ray A et al.	—	2025	→
Novel Near-Infrared Fluorescent Protein for Biliverdin Biosensing with a Hydrogel Scaffold.	Zhao Y et al.	—	2025	→
Novel tools for studying the fish growth hormone axis in vivo.	Fernandes GL et al.	—	2025	→
Obtaining artifact-corrected signals in fiber photometry via isosbestic signals, robust regression, and dF/F calculations.	Keevers LJ et al.	—	2025	→
Odors drive feeding through gustatory receptor neurons in <i>Drosophila</i>.	Wei H et al.	—	2025	→
Olfactory projection neuron rewiring in the brain of an ecological specialist.	Dürr BR et al.	—	2025	→
Olfactory Receptor Responses to Pure Odorants in Drosophila melanogaster.	Lüdke A et al.	—	2025	→
Oligodendrocyte precursor cell-specific blocking of low-glucose-induced activation of AMPK ensures myelination and remyelination.	Sun Y et al.	—	2025	→
Optical Single-Channel Recording via Diffusional Confinement in Membrane Tethers.	Howell MR et al.	—	2025	→
Optimized genetic tools for neuroanatomical and functional mapping of the Aedes aegypti olfactory system.	Shankar S et al.	—	2025	→
Orexin population activity precisely reflects net body movement across behavioral and metabolic states.	Tesmer AL et al.	—	2025	→
Oxytocin induces embryonic diapause.	Minder JL et al.	—	2025	→
Paradoxical increases in anterior cingulate cortex activity during nitrous oxide-induced analgesia reveal a signature of pain affect.	Weinrich JAP et al.	—	2025	→
Patchy striatonigral neurons modulate locomotor vigor in response to environmental valence.	Hawes S et al.	—	2025	→
Phospholipid scramblases TMEM16F and Xkr8 mediate distinct features of phosphatidylserine (PS) externalization and immune suppression to promote tumor growth.	Gadiyar V et al.	—	2025	→
PIEZO1-dependent mode switch of neuronal migration in heterogeneous microenvironments in the developing brain.	Nakazawa N et al.	—	2025	→
Plasma membrane-associated calcium signaling modulates zinc homeostasis in Arabidopsis.	Fang Y et al.	—	2025	→
Population imaging of internal state circuits relevant to psychiatric disease: a review.	Silva SADCE et al.	—	2025	→
Possible brain regions involved in parturition in mice.	Wang X et al.	—	2025	→
Potassium extrusion by plant cells: evolution from an emergency valve to a driver of long-distance transport.	Hmidi D et al.	—	2025	→
Preserving spatial and quantitative information in unpaired biomedical image-to-image translation.	You JY et al.	—	2025	→
Principles and Design of Molecular Tools for Sensing and Perturbing Cell Surface Receptor Activity.	Sescil J et al.	—	2025	→
Probabilistically constrained vector summation of motion direction in the mouse superior colliculus.	Li C et al.	—	2025	→
Probing neuronal activity with genetically encoded calcium and voltage fluorescent indicators.	Sakamoto M et al.	—	2025	→
Probing spatiotemporally organized GPCR signaling using genetically encoded molecular tools.	Kwon Y et al.	—	2025	→
Pro-inflammatory effects of inhaled Great Salt Lake dust particles.	Cowley JM et al.	—	2025	→
Protein Engineering for Spatiotemporally Resolved Cellular Monitoring.	Zhou G et al.	—	2025	→
Protein-responsive gut hormone tachykinin directs food choice and impacts lifespan.	Ahrentløv N et al.	—	2025	→
Protocol for GCaMP expression and in vivo calcium imaging of medial prefrontal cortex neurons in freely behaving HIV-1 Tat transgenic mice.	Yadav-Samudrala BJ et al.	—	2025	→
Protocol for in vivo recording of neural activity in deep structures of mice brain via gradient lenses by calcium imaging.	Cherepanov S et al.	—	2025	→
Protocol for wide-field brainstem imaging largely preserving the overlying cerebellum.	Hatakeyama A et al.	—	2025	→
Psilocybin's lasting action requires pyramidal cell types and 5-HT<sub>2A</sub> receptors.	Shao LX et al.	—	2025	→
Purkinje Cell Spatial Correlation Dynamics Are Key to Cerebellar Cortical Contributions to Behavior.	Streng ML et al.	—	2025	→
Quantification of the effect of hemodynamic occlusion in two-photon imaging of mouse cortex.	Yogesh B et al.	—	2025	→
Quantitative approaches for studying G protein-coupled receptor signalling and pharmacology.	Pearce A et al.	—	2025	→
Quantitative Intravital Calcium Imaging in Mouse Kidney.	Figurek A et al.	—	2025	→
Radial astroglia cooperate with microglia to clear neuronal cell bodies during zebrafish optic tectum development.	Barber HM et al.	—	2025	→
Radiofrequency regulates the BET-mediated pathways in radial glia differentiation in human cortical development.	Cakir B et al.	—	2025	→
Rapid adaptive optics enabling near noninvasive high-resolution brain imaging in awake behaving mice.	She Z et al.	—	2025	→
Rapid neonatal AAV delivery for adult cortical two-photon imaging of genetically encoded sensors.	Wisser S et al.	—	2025	→
Reactivation of memory-associated neurons induces downstream suppression of competing neuronal populations.	Norman JF et al.	—	2025	→
Real-time visualization and modulation of endocytic dynamics in osteocytes in vivo.	Matthews MD et al.	—	2025	→
Recombinant-Chemosynthetic Biosensors for Probing Cell Surface Signaling of Red Blood Cells and Other Cells.	Ubeysinghe S et al.	—	2025	→
Red-shifted excitation enhances the sensitivity of red genetically encoded Ca<sup>2+</sup> indicator and enables crosstalk-free two-photon holographic optophysiology.	Gore PS et al.	—	2025	→
Refinement of the novel tank diving test: toward standardized and robust analysis of anxiety-like behavior in zebrafish.	Shinkai T et al.	—	2025	→
Regulation of Yeast Cytokinesis by Calcium.	Chen Q	—	2025	→
Regulatory Action of Calcium and Calcium Channels in Pain Pathways.	Zhang Y et al.	—	2025	→
Remodelling of corticostriatal axonal boutons during motor learning.	Sheng M et al.	—	2025	→
Repetitive Sensory Stimulation Potentiates and Recruits Sensory-Evoked Cortical Population Activity.	Williams LE et al.	—	2025	→
Representational drift gates critical-period plasticity in mouse visual cortex.	Brown TC et al.	—	2025	→
Representations of stimulus features in the ventral hippocampus.	Biane JS et al.	—	2025	→
Retinal calcium waves coordinate uniform tissue patterning of the <i>Drosophila</i> eye.	Choi BJ et al.	—	2025	→
Reveal the mechanism of brain function with fluorescence microscopy at single-cell resolution: from neural decoding to encoding.	Li K et al.	—	2025	→
Review of cocaine-induced brain vascular and cellular function changes measured <i>in vivo</i> with optical imaging.	Du C et al.	—	2025	→
Role of complexin 2 in the regulation of hormone secretion from the islet of Langerhans.	Ng XW et al.	—	2025	→
Sarcoendoplasmic reticulum calcium ATPase is an essential and druggable lipid-dependent ion pump in Toxoplasma gondii.	Cruz-Mirón R et al.	—	2025	→
Secondary motor cortex tracks decision value during the learning of a non-instructed task.	Augusto E et al.	—	2025	→
Select autosomal dominant DFNA11 deafness variants activate Myo7A targeting in epithelial cells.	Acharya P et al.	—	2025	→
Selectively vulnerable deep cortical layer 5/6 fast-spiking interneurons in Alzheimer's disease models in vivo.	Papanikolaou A et al.	—	2025	→
Sensation is dispensable for the maturation of the vestibulo-ocular reflex.	Leary P et al.	—	2025	→
Sensitive red fluorescent indicators for real-time visualization of potassium ion dynamics in vivo.	Yang L et al.	—	2025	→
Separate brainstem circuits for fast steering and slow exploratory turns.	Xu L et al.	—	2025	→
Serotonin selectively modulates visual responses of object motion detectors in <i>Drosophila</i>.	Bertsch DJ et al.	—	2025	→
Sexual failure decreases sweet taste perception in male <i>Drosophila</i> via dopaminergic signaling.	Wang G et al.	—	2025	→
SIFa peptidergic neurons orchestrate the internal states and energy balance of male Drosophila melanogaster.	Song Y et al.	—	2025	→
Similarities and differences in the response and molecular characteristics of peripheral sensory neurons associated with pain and itch.	Liu L et al.	—	2025	→
Simultaneous recording of spikes and calcium signals in odor-evoked responses of <i>Drosophila</i> antennal neurons.	Xiao Y et al.	—	2025	→
Spatially heterogeneous acetylcholine dynamics in the striatum promote behavioral flexibility.	Sarpong GA et al.	—	2025	→
Spatial proteomics of ER tubules reveals CLMN, an ER-actin tether at focal adhesions that promotes cell migration.	Merta H et al.	—	2025	→
Spatiotemporal Characterization of the Functional MRI Latency Structure with Respect to Neural Signaling and Brain Hierarchy.	Choi H et al.	—	2025	→
Sphingosine-1-phosphate signalling activates E-Syt1 to facilitate HDL-derived cholesterol transport.	Xu Z et al.	—	2025	→
Spike rate inference from mouse spinal cord calcium imaging data.	Rupprecht P et al.	—	2025	→
Split genetically encoded calcium indicators for interorganellar junctions.	Olszakier S et al.	—	2025	→
Spontaneous Calcium Bursts Organize the Apical Actin Cytoskeleton of Multiciliated Cells.	Wiegel J et al.	—	2025	→
Spontaneous mesoscale calcium dynamics reflect the development of the modular functional architecture of the mouse cerebral cortex.	Warm D et al.	—	2025	→
Sub-cellular population imaging tools reveal stable apical dendrites in hippocampal area CA3.	Moore JJ et al.	—	2025	→
Super-resolution imaging technique for precision in vivo neuronal activity mapping.	—	—	2025	→
Supralinear dendritic integration in murine dendrite-targeting interneurons.	Griesius S et al.	—	2025	→
Swimming motions evoke Piezo1-dependent Ca<sup>2+</sup> events in vascular endothelial cells of larval zebrafish.	Jia BZ et al.	—	2025	→
Synaptic vesicle fusion promotes phosphatidylinositol 4-phosphate synthesis for efficient synaptic transmission.	Yoshida T et al.	—	2025	→
Synchronization in epithelial tissue morphogenesis.	Richa P et al.	—	2025	→
Synthetic GPCRs for programmable sensing and control of cell behaviour.	Kalogriopoulos NA et al.	—	2025	→
TAOK2 controls synaptic plasticity and anxiety via ERK and calcium signaling.	Ma W et al.	—	2025	→
The amyloid precursor family of proteins in excitatory neurons are essential for regulating cortico-hippocampal circuit dynamics in vivo.	Harris SS et al.	—	2025	→
The claustrum enhances neural variability by modulating the responsiveness of the prefrontal cortex.	Atilgan H et al.	—	2025	→
The Endoplasmic Reticulum-Located TRPV1 Channel Is Not Thermal Sensitive.	Petukhova EO et al.	—	2025	→
The estrous cycle modulates hippocampal spine dynamics, dendritic processing, and spatial coding.	Wolcott NS et al.	—	2025	→
The gut microbiota promotes pain in fibromyalgia.	Cai W et al.	—	2025	→
The history and future of resting-state functional magnetic resonance imaging.	Biswal BB et al.	—	2025	→
The Impact of Optical Undersampling on the Ca<sup>2+</sup> Signal Resolution in Ca<sup>2+</sup> Imaging of Spontaneous Neuronal Activity.	Milicevic KD et al.	—	2025	→
The Interplay Between CB<sub>2</sub> and NMDA Receptors in Parkinson's Disease.	Reyes-Resina I et al.	—	2025	→
The lives of cells, recorded.	Askary A et al.	—	2025	→
The malaria parasite PP1 phosphatase controls the initiation of the egress pathway of asexual blood-stages by regulating the rounding-up of the vacuole.	Seveno M et al.	—	2025	→
The Multifaceted Role of Calcium Signaling in Regulated Necrosis.	Perez-Rivera E et al.	—	2025	→
The olivocerebellar system differentially encodes the effect sensory events exert on behavior.	Scheer I et al.	—	2025	→
The projection from the rostral anterior cingulate cortex to the ventral tegmental area regulates 5-HT-induced itch aversion and scratching in rats.	Teng JF et al.	—	2025	→
The rice cation/calcium exchanger OsCCX2 is involved in calcium signal clearance and osmotic tolerance.	Hao X et al.	—	2025	→
TMBIM-2 orchestrates systemic mitochondrial stress response via facilitating Ca2+ oscillations.	Li J et al.	—	2025	→
TMEM65 functions as the mitochondrial Na<sup>+</sup>/Ca<sup>2+</sup> exchanger.	Zhang JL et al.	—	2025	→
Topographic correspondence between retinotopic and whisker somatosensory map in mouse higher visual area and its development.	Matsumoto H et al.	—	2025	→
Transparent, flexible graphene-ITO-based neural microelectrodes for simultaneous electrophysiology recording and calcium imaging of intracortical neural activity in freely moving mice.	Yuan M et al.	—	2025	→
Two-photon fiberscope with a proactive optoelectrical commutator for rotational resistance-free imaging in freely behaving rodents.	Liu Y et al.	—	2025	→
Two-Photon Microscopy to Measure Calcium Signaling in the Living Brain.	Curtis KA et al.	—	2025	→
Ultrafast optical imaging techniques for exploring rapid neuronal dynamics.	Nguyen TN et al.	—	2025	→
Unifying community whole-brain imaging datasets enables robust neuron identification and reveals determinants of neuron position in C. elegans.	Sprague DY et al.	—	2025	→
Unique Role of Intracellular Perinuclear β<sub>1</sub>-Adrenergic Receptors in Defining Signaling Compartmentation and Pathological Cardiac Remodeling.	Turcotte MG et al.	—	2025	→
Unraveling the neural code: analysis of large-scale two-photon microscopy data.	Saito Y et al.	—	2025	→
Using in vivo calcium imaging to examine joint neuron spontaneous activity and home cage analysis to monitor activity changes in mouse models of arthritis.	Goodwin GL et al.	—	2025	→
Vagal pathway activation links chronic stress to decline in intestinal stem cell function.	Zhang G et al.	—	2025	→
Viral Vector Eluting Lenses for Single-Step Targeted Expression of Genetically-Encoded Activity Sensors for in Vivo Microendoscopic Calcium Imaging.	Jons CK et al.	—	2025	→
Visual circuitry for distance estimation in Drosophila.	Shomar JW et al.	—	2025	→
Voltage-gated calcium channels generate blastema Ca2+ fluxes restraining zebrafish fin regenerative outgrowth.	Le Bleu HK et al.	—	2025	→
VTA projections to M1 are essential for reorganization of layer 2-3 network dynamics underlying motor learning.	Ghanayim A et al.	—	2025	→
Wearable optical coherence tomography angiography probe with extended depth of field.	Li X et al.	—	2025	→
Whether or not to act is determined by distinct signals from motor thalamus and orbitofrontal cortex to secondary motor cortex.	Yoshida E et al.	—	2025	→
Window into the Brain: In Vivo Multiphoton Imaging.	Latifi S et al.	—	2025	→
X-ray crystallographic and hydrogen deuterium exchange studies confirm alternate kinetic models for homolog insulin monomers.	Ayan E et al.	—	2025	→
δ-Cells Control a Subset of β-Cells in Mouse Pancreatic Islets.	Miranda C et al.	—	2025	→
Aberrant cortical activity, functional connectivity, and neural assembly architecture after photothrombotic stroke in mice.	Bandet MV et al.	—	2024	→
Aberrant hippocampal Ca<sup>2+</sup> microwaves following synapsin-dependent adeno-associated viral expression of Ca<sup>2+</sup> indicators.	Masala N et al.	—	2024	→
A body-brain circuit that regulates body inflammatory responses.	Jin H et al.	—	2024	→
A bright cyan fluorescence calcium indicator for mitochondrial calcium with minimal interference from physiological pH fluctuations.	Gu W et al.	—	2024	→
A Cataract-Causing Mutation in the TRPM3 Cation Channel Disrupts Calcium Dynamics in the Lens.	Zhou Y et al.	—	2024	→
Accurate neuron segmentation method for one-photon calcium imaging videos combining convolutional neural networks and clustering.	Bao Y et al.	—	2024	→
A conserved phenylalanine motif among teleost fish provides insight for improving electromagnetic perception.	Ricker B et al.	—	2024	→
A consistent map in the medial entorhinal cortex supports spatial memory.	Malone TJ et al.	—	2024	→
Activation of PIEZO1 Attenuates Kidney Cystogenesis In Vitro and Ex Vivo.	Fan Q et al.	—	2024	→
Activity-dependent recruitment of inhibition and excitation in the awake mammalian cortex during electrical stimulation.	Dadarlat MC et al.	—	2024	→
Activity Monitoring for Analysis of Sleep in <i>Drosophila melanogaster</i>.	Sitaraman D et al.	—	2024	→
Acute contact with profibrotic macrophages mechanically activates fibroblasts via αvβ3 integrin-mediated engagement of Piezo1.	Ezzo M et al.	—	2024	→
Adaptation to visual sparsity enhances responses to isolated stimuli.	Gou T et al.	—	2024	→
Adult neurogenesis improves spatial information encoding in the mouse hippocampus.	Frechou MA et al.	—	2024	→
A fully human IgG1 antibody targeting connexin 32 extracellular domain blocks CMTX1 hemichannel dysfunction in an in vitro model.	Tettey-Matey A et al.	—	2024	→
A GCaMP reporter mouse with chondrocyte specific expression of a green fluorescent calcium indicator.	Tsadaris SA et al.	—	2024	→
A latent pool of neurons silenced by sensory-evoked inhibition can be recruited to enhance perception.	Gauld OM et al.	—	2024	→
All-optical interrogation of millimeter-scale networks and application to developing ferret cortex.	Mulholland HN et al.	—	2024	→
Altered GM1 catabolism affects NMDAR-mediated Ca<sup>2+</sup> signaling at ER-PM junctions and increases synaptic spine formation in a GM1-gangliosidosis model.	Weesner JA et al.	—	2024	→
A machine learning based method for tracking of simultaneously imaged neural activity and body posture of freely moving maggot.	Huang Z et al.	—	2024	→
A machine-learning tool to identify bistable states from calcium imaging data.	Varma A et al.	—	2024	→
A microfluidic chip for immobilization and imaging of Ciona intestinalis larvae.	Poncelet G et al.	—	2024	→
A modular and adaptable analysis pipeline to compare slow cerebral rhythms across heterogeneous datasets.	Gutzen R et al.	—	2024	→
A modular chemigenetic calcium indicator for multiplexed in vivo functional imaging.	Farrants H et al.	—	2024	→
A Monochromatically Excitable Green-Red Dual-Fluorophore Fusion Incorporating a New Large Stokes Shift Fluorescent Protein.	Ejike JO et al.	—	2024	→
A multicolor suite for deciphering population coding of calcium and cAMP in vivo.	Yokoyama T et al.	—	2024	→
Amyloid Pathology Impairs Experience-Dependent Inhibitory Synaptic Plasticity.	Niraula S et al.	—	2024	→
Amyloid-β Causes NMDA Receptor Dysfunction and Dendritic Spine Loss through mGluR1 and AKAP150-Anchored Calcineurin Signaling.	Prikhodko O et al.	—	2024	→
Analysis methods for large-scale neuronal recordings.	Stringer C et al.	—	2024	→
An atlas of GPCRs in dopamine neurons: Identification of the free fatty acid receptor 4 as a regulator of food and water intake.	Apuschkin M et al.	—	2024	→
An end-to-end recurrent compressed sensing method to denoise, detect and demix calcium imaging data.	Zhang K et al.	—	2024	→
An engineered human cardiac tissue model reveals contributions of systemic lupus erythematosus autoantibodies to myocardial injury.	Fleischer S et al.	—	2024	→
An excitatory projection from the basal forebrain to the ventral tegmental area that underlies anorexia-like phenotypes.	Cai J et al.	—	2024	→
An expanded neurogenetic toolkit to decode olfaction in the African malaria mosquito Anopheles gambiae.	Giraldo D et al.	—	2024	→
An induced pluripotent stem cell line carrying a silencing-resistant calcium reporter allele.	Durens M et al.	—	2024	→
A nondestructive membrane engineering method using an amphiphilic polymer.	Kim NH et al.	—	2024	→
A normative framework dissociates need and motivation in hypothalamic neurons.	Kim KS et al.	—	2024	→
Anterior cingulate cross-hemispheric inhibition via the claustrum resolves painful sensory conflict.	Koga K et al.	—	2024	→
Anti-microbial cetylpyridinium chloride suppresses mast cell function by targeting tyrosine phosphorylation of Syk kinase.	Obeng B et al.	—	2024	→
A paradigm for ethanol consumption in head-fixed mice during prefrontal cortical two-photon calcium imaging.	Kalelkar A et al.	—	2024	→
A population code for spatial representation in the zebrafish telencephalon.	Yang C et al.	—	2024	→
Applications of multiphoton microscopy in imaging cerebral and retinal organoids.	Lacin ME et al.	—	2024	→
A Prelimbic Cortex-Thalamus Circuit Bidirectionally Regulates Innate and Stress-Induced Anxiety-Like Behavior.	Zhang SR et al.	—	2024	→
A pupillary contrast response in mice and humans: Neural mechanisms and visual functions.	Fitzpatrick MJ et al.	—	2024	→
A REM-active basal ganglia circuit that regulates anxiety.	Ba W et al.	—	2024	→
ARViS: a bleed-free multi-site automated injection robot for accurate, fast, and dense delivery of virus to mouse and marmoset cerebral cortex.	Nomura S et al.	—	2024	→
A Semi-supervised Pipeline for Accurate Neuron Segmentation with Fewer Ground Truth Labels.	Baker CM et al.	—	2024	→
A Simple Chiral <sup>1</sup>H NMR Method for the Discrimination of (<i>R</i>)- and (<i>S</i>)-Cannabichromene in Complex Natural Mixtures and Their Effects on TRPA1 Activity.	Dadiotis E et al.	—	2024	→
A simple MATLAB toolbox for analyzing calcium imaging data in vitro and in vivo.	Desai NS et al.	—	2024	→
Assessing spontaneous sensory neuron activity using in vivo calcium imaging.	Ingram S et al.	—	2024	→
Assessment of the effect of tricaine (MS-222)-induced anesthesia on brain-wide neuronal activity of zebrafish (<i>Danio rerio</i>) larvae.	Ohnesorge N et al.	—	2024	→
Astrocyte Ca<sup>2+</sup> in the dorsal striatum suppresses neuronal activity to oppose cue-induced reinstatement of cocaine seeking.	Tavakoli NS et al.	—	2024	→
A subcortical feeding circuit linking an interoceptive node to jaw movement.	Kosse C et al.	—	2024	→
Asymmetric neurons are necessary for olfactory learning in the Drosophila brain.	Abubaker MB et al.	—	2024	→
A tripartite organelle platform links growth factor receptor signaling to mitochondrial metabolism.	Mesa D et al.	—	2024	→
Auditory discrimination learning differentially modulates neural representation in auditory cortex subregions and inter-areal connectivity.	Wang M et al.	—	2024	→
Behavioral discrimination and olfactory bulb encoding of odor plume intermittency.	Gumaste A et al.	—	2024	→
Bioisosteric analogs of MDMA: Improving the pharmacological profile?	Alberto-Silva AS et al.	—	2024	→
Blue-shifted genetically encoded Ca<sup>2+</sup> indicator with enhanced two-photon absorption.	Aggarwal A et al.	—	2024	→
Cadmium inhibits calcium activity in hippocampal CA1 neurons of freely moving mice.	Matsushita MT et al.	—	2024	→
CalciSeg: A versatile approach for unsupervised segmentation of calcium imaging data.	Günzel Y et al.	—	2024	→
Calcium Indicators with Fluorescence Lifetime-Based Signal Readout: A Structure-Function Study.	Simonyan TR et al.	—	2024	→
Calcium-permeable AMPA receptors govern PV neuron feature selectivity.	Hong I et al.	—	2024	→
Cannabinoid regulation of angiotensin II-induced calcium signaling in striatal neurons.	Rivas-Santisteban R et al.	—	2024	→
Ca<sup>2+</sup>/calmodulin-mediated desensitization of glutamate receptors shapes plant systemic wound signalling and anti-herbivore defence.	Yan C et al.	—	2024	→
Ca<sup>2+</sup> Imaging in Immature Cortical Neurons.	Horigane SI et al.	—	2024	→
Cell-type-specific hypothalamic pathways to brainstem drive context-dependent strategies in response to stressors.	Ahmadlou M et al.	—	2024	→
Cellular resolution contributions to ictal population signals.	Lau LA et al.	—	2024	→
Central Role of Hypothalamic Circuits for Acupuncture's Anti-Parkinsonian Effects.	Oh JY et al.	—	2024	→
Cerebellar Heterogeneity and Selective vulnerability in Spinocerebellar Ataxia Type 1 (SCA1).	Hamel K et al.	—	2024	→
Changes in ethanol effects in knock-in mice expressing ethanol insensitive alpha1 and alpha2 glycine receptor subunits.	San Martin LS et al.	—	2024	→
CHD2 Regulates Neuron-Glioma Interactions in Pediatric Glioma.	Zhang X et al.	—	2024	→
Chemosensory detection of polyamine metabolites guides <i>C. elegans</i> to nutritive microbes.	Brissette B et al.	—	2024	→
Claustrum modulation drives altered prefrontal cortex dynamics and connectivity.	Zahacy R et al.	—	2024	→
Closed-loop experiments and brain machine interfaces with multiphoton microscopy.	Hira R	—	2024	→
Clustered synapses develop in distinct dendritic domains in visual cortex before eye opening.	Leighton AH et al.	—	2024	→
Coexistence of state, choice, and sensory integration coding in barrel cortex LII/III.	Gardères PM et al.	—	2024	→
Combinatorial Engineering of <i>Escherichia coli</i> for Enhancing 3-Fucosyllactose Production.	Huang H et al.	—	2024	→
Common modular architecture across diverse cortical areas in early development.	Powell NJ et al.	—	2024	→
Complexin-1 enhances ultrasound neurotransmission in the mammalian auditory pathway.	Liu M et al.	—	2024	→
Comprehensive review of indicators and techniques for optical mapping of intracellular calcium ions.	Sheng CQ et al.	—	2024	→
Comprehensive software suite for functional analysis and synaptic input mapping of dendritic spines imaged <i>in vivo</i>.	Yu Y et al.	—	2024	→
Cone-Opponent Ganglion Cells in the Primate Fovea Tuned to Noncardinal Color Directions.	Godat T et al.	—	2024	→
Confinement controls the directional cell responses to fluid forces.	Amiri F et al.	—	2024	→
Conservation of Long-Range Signaling in Land Plants via Glutamate Receptor-Like Channels.	Toyota M	—	2024	→
Cooperative thalamocortical circuit mechanism for sensory prediction errors.	Furutachi S et al.	—	2024	→
Correlated signatures of social behavior in cerebellum and anterior cingulate cortex.	Hur SW et al.	—	2024	→
Coupling Nanoscale Precision with Multiscale Imaging: A Multifunctional Near-Infrared Dye for the Brain.	Liu X et al.	—	2024	→
DART.2: bidirectional synaptic pharmacology with thousandfold cellular specificity.	Shields BC et al.	—	2024	→
Decoding multi-limb movements from two-photon calcium imaging of neuronal activity using deep learning.	Park S et al.	—	2024	→
Decoding state-dependent cortical-cerebellar cellular functional connectivity in the mouse brain.	Yan Y et al.	—	2024	→
Deep-Learning-Based Segmentation of Cells and Analysis (DL-SCAN).	Bhattarai A et al.	—	2024	→
Deep-prior ODEs augment fluorescence imaging with chemical sensors.	Pham TA et al.	—	2024	→
Delayed recruitment of activity-dependent bulk endocytosis in Fmr1 knockout neurons.	Kim N et al.	—	2024	→
Deletion of the auxiliary α2δ1 voltage sensitive calcium channel subunit in osteocytes and late-stage osteoblasts impairs femur strength and load-induced bone formation in male mice.	Wright CS et al.	—	2024	→
Demixing fluorescence time traces transmitted by multimode fibers.	Rimoli CV et al.	—	2024	→
Dendritic mGluR2 and perisomatic Kv3 signaling regulate dendritic computation of mouse starburst amacrine cells.	Acarón Ledesma H et al.	—	2024	→
Descending networks transform command signals into population motor control.	Braun J et al.	—	2024	→
Designing artificial fluorescent proteins and biosensors by genetically encoding molecular rotor-based amino acids.	Hu L et al.	—	2024	→
Destabilized near-infrared fluorescent nanobodies enable background-free targeting of GFP-based biosensors for imaging and manipulation.	Barykina NV et al.	—	2024	→
Detection of ER Stress in iPSC-Derived Neurons Carrying the p.N370S Mutation in the <i>GBA1</i> Gene.	Yarkova ES et al.	—	2024	→
Developmental encoding of natural sounds in the mouse auditory cortex.	Zucca S et al.	—	2024	→
Development of a 3-dimensional organotypic model with characteristics of peripheral sensory nerves.	Koyanagi M et al.	—	2024	→
Development of activity-based anorexia requires PKC-δ neurons in two central extended amygdala nuclei.	Schnapp WI et al.	—	2024	→
Development of a Dual Reporter System to Simultaneously Visualize Ca<sup>2+</sup> Signals and AMPK Activity.	Erdoğan YC et al.	—	2024	→
[Development of fluorescent imaging sensors based on proteins].	Hario S et al.	—	2024	→
Diazirine-AIOC-NAADP, a Clickable-Photoactive NAADP Analog for Sea Urchin NAADP Binding Proteins.	Zhang Y et al.	—	2024	→
Dietary L-Glu sensing by enteroendocrine cells adjusts food intake via modulating gut PYY/NPF secretion.	Gao J et al.	—	2024	→
Differential Encoding of Two-Tone Harmonics in the Male and Female Mouse Auditory Cortex.	De A et al.	—	2024	→
Disease-relevant upregulation of P2Y<sub>1</sub> receptor in astrocytes enhances neuronal excitability via IGFBP2.	Shigetomi E et al.	—	2024	→
Distinct subpopulations of ventral pallidal cholinergic projection neurons encode valence of olfactory stimuli.	Kim R et al.	—	2024	→
Distributed feature representations of natural stimuli across parallel retinal pathways.	Hsiang JC et al.	—	2024	→
Divergent recruitment of developmentally defined neuronal ensembles supports memory dynamics.	Kveim VA et al.	—	2024	→
Diving head-first into brain intravital microscopy.	Suthya AR et al.	—	2024	→
Diving into drug-screening: zebrafish embryos as an in vivo platform for antimicrobial drug discovery and assessment.	Habjan E et al.	—	2024	→
Diving into the zebrafish brain: exploring neuroscience frontiers with genetic tools, imaging techniques, and behavioral insights.	Doszyn O et al.	—	2024	→
Dopamine biases decisions by limiting temporal integration.	Gautham AK et al.	—	2024	→
Dopamine dynamics are dispensable for movement but promote reward responses.	Cai X et al.	—	2024	→
Dopamine-mediated formation of a memory module in the nucleus accumbens for goal-directed navigation.	Jung K et al.	—	2024	→
Dopamine projections to the basolateral amygdala drive the encoding of identity-specific reward memories.	Sias AC et al.	—	2024	→
Dynamic changes in the hippocampal neuronal circuits activity following acute stress revealed by miniature fluorescence microscopy imaging.	Gerasimov E et al.	—	2024	→
Dynamic effects of ventral hippocampal NRG3/ERBB4 signaling on nicotine withdrawal-induced responses.	Fisher ML et al.	—	2024	→
Dynamic encoding of temperature in the central circadian circuit coordinates physiological activities.	Li H et al.	—	2024	→
Dynamic ensemble balance in direct- and indirect-pathway striatal projection neurons underlying decision-related action selection.	Tang S et al.	—	2024	→
Dynamics of directional motor tuning in the primate premotor and primary motor cortices during sensorimotor learning.	Ebina T et al.	—	2024	→
Dynamic temperature control in microfluidics for in vivo imaging of cold-sensing in C. elegans.	Lee SA et al.	—	2024	→
Early and late place cells during postnatal development of the hippocampus.	Wang C et al.	—	2024	→
Egocentric neural representation of geometric vertex in the retrosplenial cortex.	Park K et al.	—	2024	→
Egocentric processing of items in spines, dendrites, and somas in the retrosplenial cortex.	Cheng N et al.	—	2024	→
Embryos assist morphogenesis of others through calcium and ATP signaling mechanisms in collective teratogen resistance.	Tung A et al.	—	2024	→
Engineered myovascular tissues for studies of endothelial/satellite cell interactions.	Broer T et al.	—	2024	→
Engineering a human P2X2 receptor with altered ligand selectivity in yeast.	Gardner EC et al.	—	2024	→
Engineering paralog-specific PSD-95 recombinant binders as minimally interfering multimodal probes for advanced imaging techniques.	Rimbault C et al.	—	2024	→
Exploiting Cell-Based Assays to Accelerate Drug Development for G Protein-Coupled Receptors.	Wu Y et al.	—	2024	→
Exploration biases forelimb reaching strategies.	Mosberger AC et al.	—	2024	→
Exploring pancreatic beta-cell subgroups and their connectivity.	Rutter GA et al.	—	2024	→
Expression of GCaMP6s in the dentate gyrus induces tonic-clonic seizures.	Teng S et al.	—	2024	→
Fast Inhibition Slows and Desynchronizes Mouse Auditory Efferent Neuron Activity.	Fischl M et al.	—	2024	→
Feedforward and disinhibitory circuits differentially control activity of cortical somatostatin interneurons during behavioral state transitions.	de Brito Van Velze M et al.	—	2024	→
Fiber photometry in neuroscience research: principles, applications, and future directions.	Kielbinski M et al.	—	2024	→
Fillable Magnetic Microrobots for Drug Delivery to Cardiac Tissues In Vitro.	Chen MS et al.	—	2024	→
Flexibility of intrinsic neural timescales during distinct behavioral states.	Çatal Y et al.	—	2024	→
Flexible adjustment of oxytocin neuron activity in mouse dams revealed by microendoscopy.	Yaguchi K et al.	—	2024	→
Fluorescent Protein-Based Sensors for Detecting Essential Metal Ions across the Tree of Life.	Jensen GC et al.	—	2024	→
Fractured columnar small-world functional network organization in volumes of L2/3 of mouse auditory cortex.	Bowen Z et al.	—	2024	→
GABAergic amacrine cells balance biased chromatic information in the mouse retina.	Korympidou MM et al.	—	2024	→
GABAergic disinhibition from the BNST to PNOC<sup>ARC</sup> neurons promotes HFD-induced hyperphagia.	Sotelo-Hitschfeld T et al.	—	2024	→
General anesthesia activates a central anxiolytic center in the BNST.	Lu D et al.	—	2024	→
Generalized modality responses in primary sensory neurons of awake mice during the development of neuropathic pain.	Sun L et al.	—	2024	→
Generation and application of novel hES cell reporter lines for the differentiation and maturation of hPS cell-derived islet-like clusters.	Zanfrini E et al.	—	2024	→
Generation of Connexin-Expressing Stable Cell Pools.	Tettey-Matey A et al.	—	2024	→
Generation of human cerebral organoids with a structured outer subventricular zone.	Walsh RM et al.	—	2024	→
Genetically encoded green fluorescent sensor for probing sulfate transport activity of solute carrier family 26 member a2 (Slc26a2) protein.	Lai C et al.	—	2024	→
Genetically encoded intrabody probes for labeling and manipulating AMPA-type glutamate receptors.	Kareemo DJ et al.	—	2024	→
Genetically encoded sensors for in vivo detection of neurochemicals relevant to depression.	Zhao Y et al.	—	2024	→
Genetically Encoded Sensors for the In Vivo Detection of Neurochemical Dynamics.	Yang Y et al.	—	2024	→
Geometric transformation adaptive optics (GTAO) for volumetric deep brain imaging through gradient-index lenses.	Li Y et al.	—	2024	→
Global spatiotemporal synchronizing structures of spontaneous neural activities in different cell types.	Shi L et al.	—	2024	→
GLP-1 metabolite GLP-1(9-36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion.	Gandasi NR et al.	—	2024	→
Harnessing the potential of human induced pluripotent stem cells, functional assays and machine learning for neurodevelopmental disorders.	Yang Z et al.	—	2024	→
Head-mounted central venous access during optical recordings and manipulations of neural activity in mice.	Liu C et al.	—	2024	→
Heterogeneous subpopulations of GABA<sub>A</sub>R-responding neurons coexist across neuronal network scales and developmental stages in health and disease.	Colombi I et al.	—	2024	→
Highly local activation of inhibition at the seizure wavefront in vivo.	Shah PT et al.	—	2024	→
High-Performance Chemigenetic Potassium Ion Indicator.	Cheng D et al.	—	2024	→
High-speed two-photon microscopy with adaptive line-excitation.	Li Y et al.	—	2024	→
Hijacking of internal calcium dynamics by intracellularly residing viral rhodopsins.	Eria-Oliveira AS et al.	—	2024	→
Histamine-tuned subicular circuit mediates alert-driven accelerated locomotion in mice.	Yang L et al.	—	2024	→
HIV-1 and methamphetamine co-treatment in primary human astrocytes: TAARgeting ER/UPR dysfunction.	Proulx JM et al.	—	2024	→
Homeostatic regulation of rapid eye movement sleep by the preoptic area of the hypothalamus.	Maurer JJ et al.	—	2024	→
Human birth tissue products as a non-opioid medicine to inhibit post-surgical pain.	Zhang C et al.	—	2024	→
Human iPSC-derived microglia sense and dampen hyperexcitability of cortical neurons carrying the epilepsy-associated <i>SCN2A</i>-L1342P mutation.	Que Z et al.	—	2024	→
Human TRPV1 is an efficient thermogenetic actuator for chronic neuromodulation.	Maltsev DI et al.	—	2024	→
<i>Drosophila suzukii</i> and <i>Drosophila melanogaster</i> prefer distinct microbial and plant aroma compounds in a complex fermented matrix.	Dzialo MC et al.	—	2024	→
<i>In vivo</i> imaging of the neuronal response to spinal cord injury: a narrative review.	Deng J et al.	—	2024	→
Imaging different cell populations in the mouse olfactory bulb using the genetically encoded voltage indicator ArcLight.	Leong LM et al.	—	2024	→
Imaging Single-Cell Ca<sup>2+</sup> Dynamics of Brainstem Neurons and Glia in Freely Behaving Mice.	Bhandare AM et al.	—	2024	→
Improved Sensitivity in a Modified Berkeley Red Sensor of Transmembrane Potential.	Navarro MX et al.	—	2024	→
Increased Vulnerability to Ferroptosis in FUS-ALS.	Ismail M et al.	—	2024	→
Individual Atg8 paralogs and a bacterial metabolite sequentially promote hierarchical CASM-xenophagy induction and transition.	Sakuma C et al.	—	2024	→
Inputs to the locus coeruleus from the periaqueductal gray and rostroventral medulla shape opioid-mediated descending pain modulation.	Lubejko ST et al.	—	2024	→
In Silico Analyses of Vertebrate G-Protein-Coupled Receptor Fusions United With or Without an Additional Transmembrane Sequence Indicate Classification into Three Groups of Linkers.	Kamiya T et al.	—	2024	→
Integration of Functional Human Auditory Neural Circuits Based on a 3D Carbon Nanotube System.	Lou Y et al.	—	2024	→
Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids.	Haloi N et al.	—	2024	→
Interactome Analysis Identifies the Role of BZW2 in Promoting Endoplasmic Reticulum-Mitochondria Contact and Mitochondrial Metabolism.	Maio G et al.	—	2024	→
Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice.	Pan YD et al.	—	2024	→
Intracellular calcium links milk stasis to lysosome-dependent cell death during early mammary gland involution.	Jeong J et al.	—	2024	→
Intracellular magnesium optimizes transmission efficiency and plasticity of hippocampal synapses by reconfiguring their connectivity.	Zhou H et al.	—	2024	→
Intrinsic and synaptic determinants of receptive field plasticity in Purkinje cells of the mouse cerebellum.	Lin TF et al.	—	2024	→
In vivo dual-plane 3-photon microscopy: spanning the depth of the mouse neocortex.	Cloves M et al.	—	2024	→
Isolation of psychedelic-responsive neurons underlying anxiolytic behavioral states.	Muir J et al.	—	2024	→
Ketamine alleviates NMDA receptor hypofunction through synaptic trapping.	Villéga F et al.	—	2024	→
Large-scale calcium imaging reveals a systematic V4 map for encoding natural scenes.	Wang T et al.	—	2024	→
Lateral entorhinal cortex subpopulations represent experiential epochs surrounding reward.	Issa JB et al.	—	2024	→
Latest assessment methods for mitochondrial homeostasis in cognitive diseases.	You W et al.	—	2024	→
Learning enhances behaviorally relevant representations in apical dendrites.	Benezra SE et al.	—	2024	→
Learning, Fast and Slow: Single- and Many-Shot Learning in the Hippocampus.	Liao Z et al.	—	2024	→
LGR signaling mediates muscle-adipose tissue crosstalk and protects against diet-induced insulin resistance.	Kubrak O et al.	—	2024	→
Lights, fiber, action! A primer on in vivo fiber photometry.	Simpson EH et al.	—	2024	→
Link Brain-Wide Projectome to Neuronal Dynamics in the Mouse Brain.	Li X et al.	—	2024	→
Live-Cell Fluorescence Imaging for Virus-Host Interactions.	Scribano FJ et al.	—	2024	→
Local changes in potassium ions regulate input integration in active dendrites.	Nordentoft MS et al.	—	2024	→
Longitudinal changes in electrophysiology and widefield calcium imaging following electrode implantation.	Robbins C et al.	—	2024	→
Long-lasting forms of plasticity through patterned ultrasound-induced brainwave entrainment.	Kim HJ et al.	—	2024	→
Long-range inhibition from prelimbic to cingulate areas of the medial prefrontal cortex enhances network activity and response execution.	Utashiro N et al.	—	2024	→
Long-term, high-resolution in vivo calcium imaging in pigeons.	Nimpf S et al.	—	2024	→
Long-term mesoscale imaging of 3D intercellular dynamics across a mammalian organ.	Zhang Y et al.	—	2024	→
Low-cost Polyethylene Terephthalate Lamination Microfluidics Designs for Multiplexed Zebrafish Imaging.	Tan S et al.	—	2024	→
Low-cost reversible tandem lens mesoscope for brain imaging in rodents.	Jose A et al.	—	2024	→
Machine learning-guided engineering of genetically encoded fluorescent calcium indicators.	Wait SJ et al.	—	2024	→
Macrophages enhance contractile force in iPSC-derived human engineered cardiac tissue.	Lock RI et al.	—	2024	→
Macrophages preserve endothelial cell specialization in the adrenal gland to modulate aldosterone secretion and blood pressure.	Fan Z et al.	—	2024	→
Magnesium vs. sodium alginate as precursors of calcium alginate: Mechanical differences and advantages in the development of functional neuronal networks.	Della Rosa G et al.	—	2024	→
Magnetic voluntary head-fixation in transgenic rats enables lifespan imaging of hippocampal neurons.	Rich PD et al.	—	2024	→
Mapping brain state-dependent sensory responses across the mouse cortex.	Montagni E et al.	—	2024	→
Mapping the neural dynamics of locomotion across the Drosophila brain.	Brezovec BE et al.	—	2024	→
Measurement of Ca<sup>2+</sup> Uptake Through Connexin Hemichannels.	Nardin C et al.	—	2024	→
Mechanism of barotaxis in marine zooplankton.	Bezares Calderón LA et al.	—	2024	→
Mechanism of sensory perception unveiled by simultaneous measurement of membrane voltage and intracellular calcium.	Tokunaga T et al.	—	2024	→
Merkel cells and keratinocytes in oral mucosa are activated by mechanical stimulation.	Tong CK et al.	—	2024	→
Mesoaccumbal glutamate neurons drive reward via glutamate release but aversion via dopamine co-release.	Warlow SM et al.	—	2024	→
Mesolimbic Neural Response Dynamics Predict Future Individual Alcohol Drinking in Mice.	Montgomery SE et al.	—	2024	→
Mesoscopic calcium imaging in a head-unrestrained male non-human primate using a lensless microscope.	Wu J et al.	—	2024	→
Methodology for Studying Hypothalamic Regulation of Feeding Behaviors.	Davenport JB et al.	—	2024	→
Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes.	Scheiblich H et al.	—	2024	→
Mineralocorticoid Receptor Antagonism Reduces Inflammatory Pain Measures in Mice Independent of the Receptors on Sensory Neurons.	Qualls KA et al.	—	2024	→
Mitochondrial calcium uptake orchestrates vertebrate pigmentation via transcriptional regulation of keratin filaments.	Tanwar J et al.	—	2024	→
Mixed Representations of Sound and Action in the Auditory Midbrain.	Quass GL et al.	—	2024	→
Model-based correction of rapid thermal confounds in fluorescence neuroimaging of targeted perturbation.	Davoudi N et al.	—	2024	→
Modern Methods for Unraveling Cell- and Circuit-Level Mechanisms of Neurophysiological Biomarkers in Psychiatry.	Rader Groves AM et al.	—	2024	→
Molecular recording of calcium signals via calcium-dependent proximity labeling.	Kim JW et al.	—	2024	→
Molecular Spies in Action: Genetically Encoded Fluorescent Biosensors Light up Cellular Signals.	Gest AMM et al.	—	2024	→
Morphotype-specific calcium signaling in human microglia.	Nevelchuk S et al.	—	2024	→
Most dynorphin neurons in the zona incerta-perifornical area are active in waking relative to non-rapid-eye movement and rapid-eye movement sleep.	Shiromani PJ et al.	—	2024	→
Motor neurons are dispensable for the assembly of a sensorimotor circuit for gaze stabilization.	Goldblatt D et al.	—	2024	→
mRNA-encoded fluorescent proteins enable superior organelle labeling for live cell imaging.	Wang J et al.	—	2024	→
Multi-color fluorescence live-cell imaging in Dictyostelium discoideum.	Hashimura H et al.	—	2024	→
Multiphoton fluorescence microscopy for in vivo imaging.	Xu C et al.	—	2024	→
Negative feedback control of hypothalamic feeding circuits by the taste of food.	Aitken TJ et al.	—	2024	→
NeMeHg, genetically encoded indicator for mercury ions based on mNeonGreen green fluorescent protein and merP protein from <i>Shigella flexneri</i>.	Subach OM et al.	—	2024	→
Neocortical inhibitory imbalance predicts successful sensory detection.	Deister CA et al.	—	2024	→
Neural and behavioural state switching during hippocampal dentate spikes.	Farrell JS et al.	—	2024	→
Neural Network Mechanisms Underlying General Anesthesia: Cortical and Subcortical Nuclei.	Hu Y et al.	—	2024	→
Neural pathways and computations that achieve stable contrast processing tuned to natural scenes.	Gür B et al.	—	2024	→
NeuroART: Real-Time Analysis and Targeting of Neuronal Population Activity during Calcium Imaging for Informed Closed-Loop Experiments.	Bowen Z et al.	—	2024	→
Neurobiological mechanisms underlying oxytocin-mediated parental behavior in rodents.	Inada K	—	2024	→
NeuroMechFly v2: simulating embodied sensorimotor control in adult Drosophila.	Wang-Chen S et al.	—	2024	→
Neuronal activity-driven O-GlcNAcylation promotes mitochondrial plasticity.	Yu SB et al.	—	2024	→
Neuronal activity inhibits mitochondrial transport only in synaptically connected segments of the axon.	Venneman T et al.	—	2024	→
Neuronal circuit mechanisms of competitive interaction between action-based and coincidence learning.	Rozenfeld E et al.	—	2024	→
Neuronal sensorimotor integration guiding salt concentration navigation in <i>Caenorhabditis elegans</i>.	Matsumoto A et al.	—	2024	→
NeuroSeg-III: efficient neuron segmentation in two-photon Ca<sup>2+</sup> imaging data using self-supervised learning.	Wu Y et al.	—	2024	→
Neurovascular effects of cocaine: relevance to addiction.	Clare K et al.	—	2024	→
New rabies viral resources for multi-scale neural circuit mapping.	Bouin A et al.	—	2024	→
Next-Generation Genetically Encoded Fluorescent Biosensors Illuminate Cell Signaling and Metabolism.	Frei MS et al.	—	2024	→
Noncanonical function of folate through folate receptor 1 during neural tube formation.	Balashova OA et al.	—	2024	→
Nonnegative matrix factorization for analyzing state dependent neuronal network dynamics in calcium recordings.	Carbonero D et al.	—	2024	→
Oligodendrocyte-axon metabolic coupling is mediated by extracellular K<sup>+</sup> and maintains axonal health.	Looser ZJ et al.	—	2024	→
Orai-mediated calcium entry determines activity of central dopaminergic neurons by regulation of gene expression.	Mitra R et al.	—	2024	→
Orexin neurons mediate temptation-resistant voluntary exercise.	Tesmer AL et al.	—	2024	→
Organization of a functional glycolytic metabolon on mitochondria for metabolic efficiency.	Wang H et al.	—	2024	→
Orthogonalization of spontaneous and stimulus-driven activity by hierarchical neocortical areal network in primates.	Matsui T et al.	—	2024	→
OrthoID: profiling dynamic proteomes through time and space using mutually orthogonal chemical tools.	Lee A et al.	—	2024	→
Osmosensor-mediated control of Ca<sup>2+</sup> spiking in pollen germination.	Pei S et al.	—	2024	→
Overlap and divergence of neural circuits mediating distinct behavioral responses to sugar.	Jacobs RV et al.	—	2024	→
Oxytocin neurons mediate stress-induced social memory impairment.	Zhan S et al.	—	2024	→
Pan-cortical 2-photon mesoscopic imaging and neurobehavioral alignment in awake, behaving mice.	Vickers ED et al.	—	2024	→
Parallel pathways carrying direction-and orientation-selective retinal signals to layer 4 of the mouse visual cortex.	Wang H et al.	—	2024	→
Perceptual constancy for an odor is acquired through changes in primary sensory neurons.	Conway M et al.	—	2024	→
Phosphorylation of Piezo1 at a single residue, serine-1612, regulates its mechanosensitivity and in vivo mechanotransduction function.	Zhang T et al.	—	2024	→
Phosphorylation of pyruvate dehydrogenase inversely associates with neuronal activity.	Yang D et al.	—	2024	→
PIEZO acts in an intestinal valve to regulate swallowing in C. elegans.	Park YJ et al.	—	2024	→
Piezo regulates epithelial topology and promotes precision in organ size control.	Mim MS et al.	—	2024	→
Plasticity-induced actin polymerization in the dendritic shaft regulates intracellular AMPA receptor trafficking.	Wong VC et al.	—	2024	→
Population coding of time-varying sounds in the nonlemniscal inferior colliculus.	Shi K et al.	—	2024	→
Precision medicine focus on the central nervous system: Non-invasive therapeutic agent delivery with focused ultrasound and microbubbles.	Mannangatti P et al.	—	2024	→
Predation without direction selectivity.	Krizan J et al.	—	2024	→
Prior Negative Experience Biases Activity of Medial Amygdala during Interstrain Social Engagement in Male Rats.	Ritger AC et al.	—	2024	→
Probing cerebellar circuit dysfunction in rodent models of spinocerebellar ataxia by means of in vivo two-photon calcium imaging.	Douthwaite C et al.	—	2024	→
Prolactin blood concentration relies on the scalability of the TIDA neurons' network efficiency <i>in vivo</i>.	Cherepanov S et al.	—	2024	→
Protocol for synchronized wireless fiber photometry and video recordings in rodents during behavior.	Tamboli S et al.	—	2024	→
Protocol to quantify the activation dynamics of tumor-associated T cells in mice by functional intravital microscopy.	Geels SN et al.	—	2024	→
Pulse-width modulated temporal interference (PWM-TI) brain stimulation.	Luff CE et al.	—	2024	→
Rapid, biochemical tagging of cellular activity history in vivo.	Zhang R et al.	—	2024	→
Rapid fluctuations in functional connectivity of cortical networks encode spontaneous behavior.	Benisty H et al.	—	2024	→
Real-time live imaging of cytosolic hydrogen peroxide and Ca<sup>2+</sup> of Marchantia polymorpha gemmalings reveal immediate initial responses of plant cells triggered by nonthermal plasma irradiation.	Tsuboyama S et al.	—	2024	→
Reconstructing Signaling Networks Using Biosensor Barcoding.	Wang S et al.	—	2024	→
Recording physiological history of cells with chemical labeling.	Huppertz MC et al.	—	2024	→
Reduction in calcium responses to whisker stimulation in the primary somatosensory and motor cortices of the model mouse with trigeminal neuropathic pain.	Kitano K et al.	—	2024	→
Reelin differentially shapes dendrite morphology of medial entorhinal cortical ocean and island cells.	Hamad MIK et al.	—	2024	→
Regulation of long-range BMP gradients and embryonic polarity by propagation of local calcium-firing activity.	Lee HC et al.	—	2024	→
Restoration of a paraventricular thalamo-accumbal behavioral suppression circuit prevents reinstatement of heroin seeking.	Paniccia JE et al.	—	2024	→
Reward contingency gates selective cholinergic suppression of amygdala neurons.	Kimchi EY et al.	—	2024	→
Role of the Nucleus Accumbens in Signaled Avoidance Actions.	Zhou J et al.	—	2024	→
Selective Modulation of Fear Memory in Non-Rapid Eye Movement Sleep.	Zheng Q et al.	—	2024	→
Self-Assembly of Microstructured Protein Coatings with Programmable Functionality for Fluorescent Biosensors.	Jo S et al.	—	2024	→
Self-organization of modular activity in immature cortical networks.	Mulholland HN et al.	—	2024	→
Sensitization of meningeal afferents to locomotion-related meningeal deformations in a migraine model.	Blaeser AS et al.	—	2024	→
Sensory experience steers representational drift in mouse visual cortex.	Bauer J et al.	—	2024	→
Sensory integration of food and population density during the diapause exit decision involves insulin-like signaling in <i>Caenorhabditis elegans</i>.	Zhang MG et al.	—	2024	→
Separate anterior paraventricular thalamus projections differentially regulate sensory and affective aspects of pain.	Mindaye SA et al.	—	2024	→
Sex peptide receptor is not required for refractoriness to remating or induction of egg laying in Aedes aegypti.	Amaro IA et al.	—	2024	→
Sexually dimorphic control of affective state processing and empathic behaviors.	Fang S et al.	—	2024	→
Simultaneous, cortex-wide dynamics of up to 1 million neurons reveal unbounded scaling of dimensionality with neuron number.	Manley J et al.	—	2024	→
Simultaneous detection of dynamic calcium signaling and ERK activity in living cells.	Zhang L et al.	—	2024	→
Simultaneous Dual-region Functional Imaging in Miniaturized Two-photon Microscopy.	Zhang Z et al.	—	2024	→
Simultaneous interneuron labeling reveals cell type-specific, population-level interactions in cortex.	Potter CT et al.	—	2024	→
Single-chain fluorescent integrators for mapping G-protein-coupled receptor agonists.	Kroning K et al.	—	2024	→
SIRT1 Coordinates Transcriptional Regulation of Neural Activity and Modulates Depression-Like Behaviors in the Nucleus Accumbens.	Kim HD et al.	—	2024	→
Skeletal myotubes expressing ALS mutant SOD1 induce pathogenic changes, impair mitochondrial axonal transport, and trigger motoneuron death.	Martínez P et al.	—	2024	→
Slow wave activity disruptions and memory impairments in a mouse model of aging.	Yu L et al.	—	2024	→
(S)-ML-SA1 Activates Autophagy via TRPML1-TFEB Pathway.	Cunha MR et al.	—	2024	→
Somatostatin interneurons control the timing of developmental desynchronization in cortical networks.	Mòdol L et al.	—	2024	→
Special Section Guest Editorial: Open-source neurophotonic tools for neuroscience.	Kodandaramaiah SB et al.	—	2024	→
Spike transmission failures in axons from cortical neurons <i>in vivo</i>.	Ofer N et al.	—	2024	→
Spine plasticity of dentate gyrus parvalbumin-positive interneurons is regulated by experience.	Kaufhold D et al.	—	2024	→
Stable sequential dynamics in prefrontal cortex represents subjective estimation of time.	Li Y et al.	—	2024	→
Stimulus information guides the emergence of behavior-related signals in primary somatosensory cortex during learning.	Panniello M et al.	—	2024	→
STING orchestrates the neuronal inflammatory stress response in multiple sclerosis.	Woo MS et al.	—	2024	→
Striatal Neurons Are Recruited Dynamically into Collective Representations of Self-Initiated and Learned Actions in Freely Moving Mice.	Tiroshi L et al.	—	2024	→
Structural and Functional Organization of Visual Responses in the Inferior Olive of Larval Zebrafish.	Félix R et al.	—	2024	→
Structural and temporal dynamics analysis of neural circuit from 2002 to 2022: A bibliometric analysis.	Liu Y et al.	—	2024	→
Structural insights into the calcium-coupled zinc export of human ZnT1.	Sun C et al.	—	2024	→
Subfield-specific interneuron circuits govern the hippocampal response to novelty in male mice.	Hainmueller T et al.	—	2024	→
Sucrose overconsumption impairs AgRP neuron dynamics and promotes palatable food intake.	Lorch CM et al.	—	2024	→
Suppression of Contraction Raises Calcium Ion Levels in the Heart of Zebrafish Larvae.	Martinez-Sielva A et al.	—	2024	→
Synaptic input and Ca<sup>2+</sup> activity in zebrafish oligodendrocyte precursor cells contribute to myelin sheath formation.	Li J et al.	—	2024	→
System-level time computation and representation in the suprachiasmatic nucleus revealed by large-scale calcium imaging and machine learning.	Wang Z et al.	—	2024	→
Targeted sonogenetic modulation of GABAergic interneurons in the hippocampal CA1 region in status epilepticus.	Xu T et al.	—	2024	→
TCAF1 promotes TRPV2-mediated Ca<sup>2+</sup> release in response to cytosolic DNA to protect stressed replication forks.	Kong L et al.	—	2024	→
Thallium's Threat to Aquatic Life: Stage-Specific Toxicity in Zebrafish Embryos and Larvae.	Liu J et al.	—	2024	→
The COMBO window: A chronic cranial implant for multiscale circuit interrogation in mice.	Edelman BJ et al.	—	2024	→
The Cousa objective: a long-working distance air objective for multiphoton imaging in vivo.	Yu CH et al.	—	2024	→
The endoplasmic reticulum plays a key role in α-cell intracellular Ca<sup>2+</sup> dynamics and glucose-regulated glucagon secretion in mouse islets.	Acreman S et al.	—	2024	→
The Expression and Functionality of CB<sub>1</sub>R-NMDAR Complexes Are Decreased in A Parkinson's Disease Model.	Reyes-Resina I et al.	—	2024	→
The generation of stable transgenic lines in the human-infective nematode Strongyloides stercoralis.	Patel R et al.	—	2024	→
The impacts of hypertonic conditions on <i>Drosophila</i> larval cool cells.	Bai H et al.	—	2024	→
The influence of cortical activity on perception depends on behavioral state and sensory context.	Russell LE et al.	—	2024	→
The Mas-related G protein-coupled receptor d (Mrgprd) mediates pain hypersensitivity in painful diabetic neuropathy.	George DS et al.	—	2024	→
The molecular basis of sugar detection by an insect taste receptor.	Gomes JV et al.	—	2024	→
The odor of a nontoxic tetrodotoxin analog, 5,6,11-trideoxytetrodotoxin, is detected by specific olfactory sensory neurons of the green spotted puffers.	Suzuki T et al.	—	2024	→
The representation of decision variables in orbitofrontal cortex is longitudinally stable.	Zhang M et al.	—	2024	→
The scale of zebrafish pectoral fin buds is determined by intercellular K+ levels and consequent Ca2+-mediated signaling via retinoic acid regulation of Rcan2 and Kcnk5b.	Jiang X et al.	—	2024	→
The secondary somatosensory cortex gates mechanical and heat sensitivity.	Taub DG et al.	—	2024	→
Timed receptor tyrosine kinase signaling couples the central and a peripheral circadian clock in <i>Drosophila</i>.	Cavieres-Lepe J et al.	—	2024	→
Time-Multiplexed Miniaturized Two-Photon Microscopy.	Liu SJ et al.	—	2024	→
Tonically active GABAergic neurons in the dorsal periaqueductal gray control instinctive escape in mice.	Stempel AV et al.	—	2024	→
Tonotopic organization of auditory cortex in awake marmosets revealed by multi-modal wide-field optical imaging.	Song X et al.	—	2024	→
Topography and Ensemble Activity in the Auditory Cortex of a Mouse Model of Fragile X Syndrome.	Wadle SL et al.	—	2024	→
Tracking the topology of neural manifolds across populations.	Yoon IHR et al.	—	2024	→
Transformation of neural coding for vibrotactile stimuli along the ascending somatosensory pathway.	Lee KS et al.	—	2024	→
Transient enhancement of stimulus-evoked activity in neocortex during sensory learning.	Zhu M et al.	—	2024	→
Trans-synaptic Association of Vesicular Zinc Transporter 3 and Shank3 Supports Synapse-Specific Dendritic Spine Structure and Function in the Mouse Auditory Cortex.	Manning A et al.	—	2024	→
TRPA1 Agonist-Responsive Afferents Contribute to Central Sensitization by Suppressing Spinal GABAergic Interneurons Through Somatostatin 2A Receptors.	Pariyar R et al.	—	2024	→
TRPC6 is a mechanosensitive channel essential for ultrasound neuromodulation in the mammalian brain.	Matsushita Y et al.	—	2024	→
Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer.	Barr J et al.	—	2024	→
Tuned geometries of hippocampal representations meet the computational demands of social memory.	Boyle LM et al.	—	2024	→
TWISP: a transgenic worm for interrogating signal propagation in Caenorhabditis elegans.	Sharma AK et al.	—	2024	→
Two-dimensional electro-optical multiphoton microscopy.	Farinella DM et al.	—	2024	→
Two-photon all-optical neurophysiology for the dissection of larval zebrafish brain functional and effective connectivity.	Turrini L et al.	—	2024	→
Two-photon imaging of excitatory and inhibitory neural response to infrared neural stimulation.	Fu P et al.	—	2024	→
Understanding Others' Distress Through Past Experiences: The Role of Memory Engram Cells in Observational Fear.	Kitamura T et al.	—	2024	→
Unlocking opioid neuropeptide dynamics with genetically encoded biosensors.	Dong C et al.	—	2024	→
Updated Toolbox for Assessing Neuronal Network Reconstruction after Cell Therapy.	Gonzalez-Ramos A et al.	—	2024	→
Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum.	Song Y et al.	—	2024	→
Utilization of the genetically encoded calcium indicator Salsa6F in cardiac applications.	Márquez-Nogueras KM et al.	—	2024	→
Ventral pallidum neurons projecting to the ventral tegmental area reinforce but do not invigorate reward-seeking behavior.	Palmer D et al.	—	2024	→
Visual experience reduces the spatial redundancy between cortical feedback inputs and primary visual cortex neurons.	Dias RF et al.	—	2024	→
Voltage-gated calcium channels act upstream of adenylyl cyclase Ac78C to promote timely initiation of dendrite regeneration.	Hertzler JI et al.	—	2024	→
Whole-Brain Calcium Imaging in <i>Drosophila</i> during Sleep and Wake.	Tainton-Heap L et al.	—	2024	→
Whole-Brain Electrophysiology and Calcium Imaging in <i>Drosophila</i> during Sleep and Wake.	Van De Poll M et al.	—	2024	→
Wide-field calcium imaging of cortical activation and functional connectivity in externally- and internally-driven locomotion.	West SL et al.	—	2024	→
A cGAL-UAS bipartite expression toolkit for <i>Caenorhabditis elegans</i> sensory neurons.	Nava S et al.	—	2023	→
A direction-selective cortico-brainstem pathway adaptively modulates innate behaviors.	Liu J et al.	—	2023	→
Aerobic glycolysis is the predominant means of glucose metabolism in neuronal somata, which protects against oxidative damage.	Wei Y et al.	—	2023	→
A neuronal coping mechanism linking stress-induced anxiety to motivation for reward.	Klenowski PM et al.	—	2023	→
Beta cell primary cilia mediate somatostatin responsiveness via SSTR3.	Adamson SE et al.	—	2023	→
Bio-friendly long-term subcellular dynamic recording by self-supervised image enhancement microscopy.	Zhang G et al.	—	2023	→
Bright and sensitive red voltage indicators for imaging action potentials in brain slices and pancreatic islets.	Han Y et al.	—	2023	→
Bring the pain: wounding reveals a transition from cortical excitability to epithelial excitability in <i>Xenopus</i> embryos.	Sepaniac LA et al.	—	2023	→
Calcium signaling mediates proliferation of the precursor cells that give rise to the ciliated left-right organizer in the zebrafish embryo.	Abdel-Razek O et al.	—	2023	→
CaMKK2 and CHK1 phosphorylate human STN1 in response to replication stress to protect stalled forks from aberrant resection.	Jaiswal RK et al.	—	2023	→
Change detection in the primate auditory cortex through feedback of prediction error signals.	Obara K et al.	—	2023	→
Circuit mechanism for suppression of frontal cortical ignition during NREM sleep.	Li B et al.	—	2023	→
Cortical circuitry mediating interareal touch signal amplification.	Ryan L et al.	—	2023	→
Headplate Installation and Craniotomy for Awake In Vivo Electrophysiological Recordings or Two-Photon Imaging of the Mouse Inferior Colliculus.	Kraakman B et al.	—	2023	→
Holistic bursting cells store long-term memory in auditory cortex.	Li R et al.	—	2023	→
Hypersensitivity to Distractors in Fragile X Syndrome from Loss of Modulation of Cortical VIP Interneurons.	Rahmatullah N et al.	—	2023	→
<i>In Vivo</i> Optical Interrogation of Neuronal Responses to Genetic, Cell Type-Specific Silencing.	Terzi F et al.	—	2023	→
In-phasic cytosolic-nuclear Ca<sup>2+</sup> rhythms in suprachiasmatic nucleus neurons.	Hiro S et al.	—	2023	→
Investigating the Influence of Morphine and Cocaine on the Mesolimbic Pathway Using a Novel Microimaging Platform.	Ganaway A et al.	—	2023	→
Meso-Py: Dual Brain Cortical Calcium Imaging in Mice during Head-Fixed Social Stimulus Presentation.	Michelson NJ et al.	—	2023	→
Mesotrode chronic simultaneous mesoscale cortical imaging and subcortical or peripheral nerve spiking activity recording in mice.	Xiao D et al.	—	2023	→
Meta-reinforcement learning via orbitofrontal cortex.	Hattori R et al.	—	2023	→
Microglial Rac1 is essential for experience-dependent brain plasticity and cognitive performance.	Socodato R et al.	—	2023	→
Modeling apical and basal tree contribution to orientation selectivity in a mouse primary visual cortex layer 2/3 pyramidal cell.	Petousakis KE et al.	—	2023	→
Modular interneuron circuits control motion sensitivity in the mouse retina.	Jo A et al.	—	2023	→
Multiple neuronal populations control the eating behavior in Hydra and are responsive to microbial signals.	Giez C et al.	—	2023	→
Norepinephrine regulates calcium signals and fate of oligodendrocyte precursor cells in the mouse cerebral cortex.	Fiore F et al.	—	2023	→
Normalization in mouse primary visual cortex.	Zayyad ZA et al.	—	2023	→
Opposing chemosensory functions of closely related gustatory receptors.	Ahn JE et al.	—	2023	→
Optimized design and in vivo application of optogenetically functionalized Drosophila dopamine receptors.	Zhou F et al.	—	2023	→
Optogenetic Microwell Array Screening System: A High-Throughput Engineering Platform for Genetically Encoded Fluorescent Indicators.	Rappleye M et al.	—	2023	→
Proposed three-phenylalanine motif involved in magnetoreception signalling of an Actinopterygii protein expressed in mammalian cells.	Ricker B et al.	—	2023	→
Prostaglandin E<sub>2</sub> Induces Long-Lasting Inhibition of Noradrenergic Neurons in the Locus Coeruleus and Moderates the Behavioral Response to Stressors.	Mukai Y et al.	—	2023	→
Protocol for the integration of fiber photometry and social behavior in rodent models.	Terstege DJ et al.	—	2023	→
Protocol to image and analyze hippocampal network dynamics in non-anesthetized mouse pups.	Ratsifandrihamanana MR et al.	—	2023	→
Rational engineering approaches for establishing insect olfaction reporters in yeast.	Hoch-Schneider EE et al.	—	2023	→
Repeated passive visual experience modulates spontaneous and non-familiar stimuli-evoked neural activity.	Niraula S et al.	—	2023	→
Spatial redundancy transformer for self-supervised fluorescence image denoising.	Li X et al.	—	2023	→
Strategic design of an NIR probe for viscosity imaging in inflammatory and non-alcoholic steatohepatitis mice.	Ma Y et al.	—	2023	→
The homeodomain transcriptional regulator DVE-1 directs a program for synapse elimination during circuit remodeling.	Alexander KD et al.	—	2023	→
Transparent Intracellular Sensing Platform with Si Needles for Simultaneous Live Imaging.	Park W et al.	—	2023	→
Wearable optical coherence tomography angiography probe for freely moving mice.	Guo X et al.	—	2023	→
Zona incerta distributes a broad movement signal that modulates behavior.	Hormigo S et al.	—	2023	→