Adolescent alcohol use is a risk factor for adult alcohol and drug dependence: evidence from a twin design.
paper
Cited
Public
Unavailable
- Authors
- Grant, Julia D; Scherrer, Jeffrey F; Lynskey, Michael T; Lyons, Michael J; Eisen, Seth A; Tsuang, Ming T; True, William R; Bucholz, Kathleen K
- Year
- 2006
- Journal
- Psychological medicine
- PMID
- 16194286
- DOI
- 10.1017/S0033291705006045
BACKGROUND: Early alcohol use is associated with abuse and dependence of licit and illicit substances later in life. The role of genetic and environmental factors in this association is not conclusive. METHOD: In 1992, data on substance use, abuse/dependence and psychiatric disorders were collected from 8169 male twin members of the Vietnam Era Twin Registry. The interview obtained age of onset of regular drinking (one drink/month for 6 or more months). Regression analyses of twin pairs discordant for early alcohol use tested whether the association between early drinking (before age 17) and adult substance use and abuse/dependence remained after controlling for genetic factors, family environment and covariates. Twin models tested for common genetic and/or environmental influences on early drinking and adult alcohol dependence and ever use and abuse/dependence on marijuana and other drugs. RESULTS: Co-twin analyses suggested the association between early regular alcohol use and adult alcohol dependence, marijuana and other drug use, and marijuana and other drug abuse/dependence could not be entirely explained by common genetic and shared family environmental factors. Genetic contributions to early regular drinking were significantly correlated with those on use of marijuana (rA=0.59), use of other drugs (rA=0.64), alcohol dependence (rA=0.54) and abuse/dependence of marijuana and other drugs (rA=0.63 and 0.66). Small but significant unique environmental correlations (rE range 0.11-0.22) indicated that familial factors could not entirely explain the association between early alcohol use and later substance use, abuse and dependence. CONCLUSIONS: Early regular drinking is associated with later alcohol dependence and use, abuse/dependence on drugs. The association is not entirely explained by genetic or shared family environmental factors. This suggests unique environmental factors contribute to transitions from early regular alcohol drinking to use, abuse and dependence on alcohol and other substances.
No figures extracted from this document.
No chunks — full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Associations Between Youth Marijuana and Alcohol Use, Neurocognitive Performance, and Triple-Network Resting-State Connectivity. | Blyth SH et al. | — | 2026 | → |
| Development of Substance Use Problems: The Role of Adolescent Cannabis Age of Onset, Frequency of Use and Childhood Risk Factors. | Hamaoui J et al. | — | 2026 | → |
| Chronic alcohol withdrawal-associated increases in VTA <i>Hcrtr1</i> expression are associated with heightened nociception and anxiety-like behavior in female rats. | Cruise S et al. | — | 2025 | → |
| Impact of Neuroimmune System Activation by Adolescent Binge Alcohol Exposure on Adult Neurobiology. | Macht V et al. | — | 2025 | → |
| Retinomics: a window to multidisease prediction using retinal biomarkers from routine eye imaging. | Yusufu M et al. | — | 2025 | → |
| The Moderating Effect of PTSD Symptoms on Associations between Minority Stressors and Alcohol Use and Related Problems in Sexual Minority Young Adults. | Basting EJ et al. | — | 2025 | → |
| Abuse-like toluene exposure during early adolescence alters subsequent ethanol and cocaine behavioral effects and brain monoamines in male mice. | Davidson CJ et al. | — | 2024 | → |
| Cannabidiol or ketamine for preventing the impact of adolescent early drug initiation on voluntary ethanol consumption in adulthood | Garcia-Fuster MJ et al. | — | 2024 | — |
| Cannabidiol or ketamine for preventing the impact of adolescent early drug initiation on voluntary ethanol consumption in adulthood. | Colom-Rocha C et al. | — | 2024 | → |
| Gender differences in alcohol drinking among adolescents: a school-based survey in China. | Li L et al. | — | 2024 | → |
| Peer bullying victimization in adolescence is associated with substance use: cross-sectional findings from French high school students. | Airagnes G et al. | — | 2024 | → |
| Prevalence and factors associated with illicit drug and high-risk alcohol use among adolescents living in urban slums of Kampala, Uganda. | Kalungi H et al. | — | 2024 | → |
| Associated and intermediate factors between genetic variants of the dopaminergic D2 receptor gene and harmful alcohol use in young adults. | Mattioni J et al. | — | 2023 | → |
| Dampened autonomic nervous system responses to stress and substance use in adolescence. | Rahal D et al. | — | 2023 | → |
| Dampened psychobiological responses to stress and substance use in adolescence. | Rahal D et al. | — | 2023 | → |
| Does polygenic risk for substance-related traits predict ages of onset and progression of symptoms? | Kranzler HR et al. | — | 2023 | → |
| Drinking motives, personality traits and life stressors-identifying pathways to harmful alcohol use in adolescence using a panel network approach. | Freichel R et al. | — | 2023 | → |
| Effects of parental mental health and family environment on impulsivity in preadolescents: a longitudinal ABCD study<sup>®</sup>. | Gebru NM et al. | — | 2023 | → |
| Influence of social rank on the development of long-term ethanol drinking trajectories in cynomolgus monkeys. | Galbo-Thomma LK et al. | — | 2023 | → |
| Prevalence of adolescent risk behaviors at 11 and 15 years of age: data from the 2004 Pelotas birth cohort. | Bozzini AB et al. | — | 2023 | → |
| Targeting Persistent Changes in Neuroimmune and Epigenetic Signaling in Adolescent Drinking to Treat Alcohol Use Disorder in Adulthood. | Crews FT et al. | — | 2023 | → |
| The predictive value of brief measures of externalizing behavior and internalizing problems in young people receiving substance use treatment: A secondary analysis. | Hesse M et al. | — | 2023 | → |
| An Exploration of Practitioners' Perceptions and Beliefs About Trauma-Informed Youth Drug Prevention Programs: a Qualitative Study. | Shin SH et al. | — | 2022 | → |
| A Review of Associations between Externalizing Behaviors and Prenatal Cannabis Exposure: Limitations & Future Directions. | Ikeda AS et al. | — | 2022 | → |
| Cultural identity affiliation and alcohol use and related consequences among American Indian and White adolescents: A latent profile analysis. | Schick MR et al. | — | 2022 | → |
| Drugs age-of-onset as a signal of later post-traumatic stress disorder: Bayesian analysis of a census protocol. | Santos LL et al. | — | 2022 | → |
| Early-Life Sleep Deprivation Enhanced Alcohol Consumption in Adolescent Rats. | Atrooz F et al. | — | 2022 | → |
| Effects of genetic risk for alcohol dependence and onset of regular drinking on the progression to alcohol dependence: A polygenic risk score approach. | Yeung EW et al. | — | 2022 | → |
| Inbred mouse strain differences in alcohol and nicotine addiction-related phenotypes from adolescence to adulthood. | Seemiller LR et al. | — | 2022 | → |
| Patterns of Violence Exposure and Substance Use among Child Welfare Involved Youth. | He AS et al. | — | 2022 | → |
| Peer-led interventions to reduce alcohol consumption in college students: A scoping review. | Lavilla-Gracia M et al. | — | 2022 | → |
| Structural differences in adolescent brains can predict alcohol misuse. | Rane RP et al. | — | 2022 | → |
| The effects of alcohol drinking on subsequent methamphetamine self-administration and relapse in adolescent female rats. | Kline HL et al. | — | 2022 | → |
| Age of Onset and Its Related Factors in Cocaine or Methamphetamine Use in Adults from the United States: Results from NHANES 2005-2018. | Guerin AA et al. | — | 2021 | → |
| Differential predictors for alcohol use in adolescents as a function of familial risk. | Tschorn M et al. | — | 2021 | → |
| Drinking Intensity at Age 29/30 as a Predictor of Alcohol Use Disorder Symptoms at Age 35 in a National Sample. | Patrick ME et al. | — | 2021 | → |
| Genotype-dependent epigenetic regulation of DLGAP2 in alcohol use and dependence. | Meng W et al. | — | 2021 | → |
| The Impact of Adolescent Alcohol Exposure on Nicotine Behavioral Sensitization in the Adult Male Neonatal Ventral Hippocampal Lesion Rat. | Sullivan EDK et al. | — | 2021 | → |
| The Relationship between Early Alcohol Use Behaviors and Adolescent Pubertal and Psychosocial Development: A Latent Growth Analysis. | May AC et al. | — | 2021 | → |
| ADHD, suicidal ideation, depression, anxiety, self-esteem, and alcohol problem in Korean juvenile delinquency. | Chung YR et al. | — | 2020 | → |
| A latent class analysis of adolescents' technology and interactive social media use: Associations with academics and substance use. | Tang S et al. | — | 2020 | → |
| Behavioral and brain signatures of substance use vulnerability in childhood. | Rapuano KM et al. | — | 2020 | → |
| Comparing the potential causal influence of two indicators of early alcohol use on later alcohol use disorder symptoms. | Davis CN et al. | — | 2020 | → |
| Psychosocial Correlates and Early Substance Abuse Associated With Lifetime Hallucinogen Use Among Hispanic Young Adults. | Yockey A et al. | — | 2020 | → |
| Response Inhibition and Binge Drinking During Transition to University: An fMRI Study. | Suárez-Suárez S et al. | — | 2020 | → |
| Structured and Unstructured Activities and Alcohol and Marijuana Use in Middle School: The Role of Availability and Engagement. | Spillane NS et al. | — | 2020 | → |
| The Association Between Age at Initiation of Alcohol Consumption and Type 2 Diabetes Mellitus: A Cohort Study of 0.5 Million Persons in China. | Li H et al. | — | 2020 | → |
| The effects of multiple early life stressors on adolescent alcohol consumption. | Thompson SM et al. | — | 2020 | → |
| The factor structure of self-esteem and its association with alcohol use in American Indian (AI) adolescents. | Schick MR et al. | — | 2020 | → |
| Valuation of peers' safe choices is associated with substance-naïveté in adolescents. | Chung D et al. | — | 2020 | → |
| An Experimental Test of Reward & Reminder as a Stand-Alone Program to Prevent Alcohol Sales to Underage Youths. | Van Ryzin MJ et al. | — | 2019 | → |
| Development of working memory in the male adolescent rat. | Kirschmann EK et al. | — | 2019 | → |
| Genetic and environmental influences on developmental trajectories of adolescent alcohol use. | Zheng Y et al. | — | 2019 | → |
| "I am spiritual, but not religious": Does one without the other protect against adolescent health-risk behaviour? | Malinakova K et al. | — | 2019 | → |
| [Problems associated with binge drinking among students in Brazil's state capitals]. | Gomes K et al. | — | 2019 | → |
| Risk profiles for heavy drinking in adolescence: differential effects of gender. | Seo S et al. | — | 2019 | → |
| Screening for Adolescent Alcohol Use in the Emergency Department: What Does It Tell Us About Cannabis, Tobacco, and Other Drug Use? | Spirito A et al. | — | 2019 | → |
| A Co-Twin Control Study of the Relationship Between Adolescent Drinking and Adult Outcomes. | Waldron JS et al. | — | 2018 | → |
| Age of Cannabis Use Onset and Adult Drug Abuse Symptoms: A Prospective Study of Common Risk Factors and Indirect Effects. | Rioux C et al. | — | 2018 | → |
| A longitudinal examination of mediational pathways linking chronic victimization and exclusion to adolescent alcohol use. | Meisel SN et al. | — | 2018 | → |
| A systematic review: Candidate gene and environment interaction on alcohol use and misuse among adolescents and young adults. | Kim J et al. | — | 2018 | → |
| Earlier alcohol use onset prospectively predicts changes in functional connectivity. | Nguyen-Louie TT et al. | — | 2018 | → |
| Marital Status as a Partial Mediator of the Associations Between Young Adult Substance Use and Subsequent Substance Use Disorder: Application of Causal Inference Methods. | Jang BJ et al. | — | 2018 | → |
| Positive alcohol use expectancies moderate the association between anxiety sensitivity and alcohol use across adolescence. | Borges AM et al. | — | 2018 | → |
| The Speed of Progression to Tobacco and Alcohol Dependence: A Twin Study. | Huggett SB et al. | — | 2018 | → |
| Adolescent alcohol exposure alters lysine demethylase 1 (LSD1) expression and histone methylation in the amygdala during adulthood. | Kyzar EJ et al. | — | 2017 | → |
| A National Swedish Longitudinal Twin-Sibling Study of alcohol use disorders among males. | Long EC et al. | — | 2017 | → |
| Earlier Alcohol Use Onset Predicts Poorer Neuropsychological Functioning in Young Adults. | Nguyen-Louie TT et al. | — | 2017 | → |
| From alcohol initiation to tolerance to problems: Discordant twin modeling of a developmental process. | Deutsch AR et al. | — | 2017 | → |
| Heavy episodic drinking and alcohol-related injuries: An open cohort study among college students. | Caamaño-Isorna F et al. | — | 2017 | → |
| Longitudinal study shows that addictive Internet use during adolescence was associated with heavy drinking and smoking cigarettes in early adulthood. | Lee BH et al. | — | 2017 | → |
| Moderation of Genetic Influences on Alcohol Involvement by Rural Residency among Adolescents: Results from the 1962 National Merit Twin Study. | Davis CN et al. | — | 2017 | → |
| Nalmefene Prevents Alcohol-Induced Neuroinflammation and Alcohol Drinking Preference in Adolescent Female Mice: Role of TLR4. | Montesinos J et al. | — | 2017 | → |
| Patterns of Alcohol Consumption in Spanish University Alumni: Nine Years of Follow-Up. | Gómez P et al. | — | 2017 | → |
| Preadolescent sensation seeking and early adolescent stress relate to at-risk adolescents' substance use by age 15. | Charles NE et al. | — | 2017 | → |
| Psychological Well-Being as a Predictor of Casual Sex Relationships and Experiences among Adolescents: A Short-Term Prospective Study. | Dubé S et al. | — | 2017 | → |
| Studies using macaque monkeys to address excessive alcohol drinking and stress interactions. | Jimenez VA et al. | — | 2017 | → |
| Testing the nicotine dependence measure mFTQ for adolescent smokers: A multinational investigation. | Prokhorov AV et al. | — | 2017 | → |
| The concurrent validity of the Problem Oriented Screening Instrument for Teenagers (POSIT) substance use/abuse subscale in adolescent patients in an urban federally qualified health center. | Kelly SM et al. | — | 2017 | → |
| The Influence of Paternal Separation, Paternal History of Alcohol Use Disorder Risk, and Early Substance Use on Offspring Educational Attainment by Young Adulthood. | Sadler BE et al. | — | 2017 | → |
| The Role of Public Health in Combatting Synthetic Cannabinoid Use in Adolescents. | Warren KE et al. | — | 2017 | → |
| A component-centered meta-analysis of family-based prevention programs for adolescent substance use. | Van Ryzin MJ et al. | — | 2016 | → |
| Alcohol and Tobacco Sales to Underage Buyers in Dutch Supermarkets: Can the Use of Age Verification Systems Increase Seller's Compliance? | Roodbeen RT et al. | — | 2016 | → |
| Alcohol consumption and accentuated personality traits among young adults in Romania: a cross-sectional study. | Rada C et al. | — | 2016 | → |
| Differences in polysubstance use among youth in the child welfare system: toward a better understanding of the highest-risk teens. | Traube DE et al. | — | 2016 | → |
| Identifying Predictors and Prevalence of Alcohol Consumption among University Students: Nine Years of Follow-Up. | Moure-Rodríguez L et al. | — | 2016 | → |
| Pharmacotherapy for Alcohol Dependence: The 2015 Recommendations of the French Alcohol Society, Issued in Partnership with the European Federation of Addiction Societies. | Rolland B et al. | — | 2016 | → |
| The usefulness of 'age at first drink' as a concept in alcohol research and prevention. | Hingson R et al. | — | 2016 | → |
| The validity of the Substance Use Risk Profile Scale (SURPS) among Australian adolescents. | Newton NC et al. | — | 2016 | → |
| Trajectories of adolescent substance use development and the influence of healthy leisure: A growth mixture modeling approach. | Weybright EH et al. | — | 2016 | → |
| Adolescent nicotine exposure fails to impact cocaine reward, aversion and self-administration in adult male rats. | Pomfrey RL et al. | — | 2015 | → |
| Adolescent rats are resistant to forming ethanol seeking habits. | Serlin H et al. | — | 2015 | → |
| Alcohol gains access to appetitive learning through adolescent heavy drinking. | DiLeo A et al. | — | 2015 | → |
| Asian American problem drinking trajectories during the transition to adulthood: ethnic drinking cultures and neighborhood contexts. | Cook WK et al. | — | 2015 | → |
| Boredom Prone or Nothing to Do? Distinguishing Between State and Trait Leisure Boredom and its Association with Substance Use in South African Adolescents. | Weybright EH et al. | — | 2015 | → |
| Bulimic Behaviors and Early Substance Use: Findings from a Cotwin-Control Study. | Munn-Chernoff MA et al. | — | 2015 | → |
| Colour Vision Impairment in Young Alcohol Consumers. | Brasil A et al. | — | 2015 | → |
| Did the 18 Drinking Age Promote High School Dropout? Implications for Current Policy. | Plunk AD et al. | — | 2015 | → |
| Normative Feedback and Adolescent Readiness to Change: A Small Randomized Trial. | Smith DC et al. | — | 2015 | → |
| Out-of-School Time and Adolescent Substance Use. | Lee KT et al. | — | 2015 | → |
| Resting-state regional cerebral blood flow during adolescence: associations with initiation of substance use and prediction of future use disorders. | Ramage AE et al. | — | 2015 | → |
| Statewide Administration of the CRAFFT Screening Tool: Highlighting the Spectrum of Substance Use. | Agley J et al. | — | 2015 | → |
| Substance use and teen pregnancy in the United States: evidence from the NSDUH 2002-2012. | Salas-Wright CP et al. | — | 2015 | → |
| Teen Alcohol Use and Social Networks: The Contributions of Friend Influence and Friendship Selection. | Cheadle JE et al. | — | 2015 | → |
| Tests of the effects of adolescent early alcohol exposures on adult outcomes. | Irons DE et al. | — | 2015 | → |
| The link between testosterone and amygdala-orbitofrontal cortex connectivity in adolescent alcohol use. | Peters S et al. | — | 2015 | → |
| Under pressure: adolescent substance users show exaggerated neural processing of aversive interoceptive stimuli. | Berk L et al. | — | 2015 | → |
| Validity and reliability of the Turkish version of CRAFFT Substance Abuse Screening Test among adolescents. | Kandemir H et al. | — | 2015 | → |
| Alcohol-induced impairment of inhibitory control is linked to attenuated brain responses in right fronto-temporal cortex. | Gan G et al. | — | 2014 | → |
| Alcohol use among Hispanic early adolescents in the United States: an examination of behavioral risk and protective profiles. | Salas-Wright CP et al. | — | 2014 | → |
| An ADH1B variant and peer drinking in progression to adolescent drinking milestones: evidence of a gene-by-environment interaction. | Olfson E et al. | — | 2014 | → |
| A pilot study of an online universal school-based intervention to prevent alcohol and cannabis use in the UK. | Newton NC et al. | — | 2014 | → |
| A prospective study of adolescent risk and protective factors for problem gambling among young adults. | Scholes-Balog KE et al. | — | 2014 | → |
| Dynamic associations among alcohol use and anxiety symptoms in early adolescence. | Pardee CS et al. | — | 2014 | → |
| Early age of alcohol initiation is not the cause of alcohol use disorders in adulthood, but is a major indicator of genetic risk. A population-based twin study. | Ystrom E et al. | — | 2014 | → |
| Gender and racial/ethnic differences in patterns of adolescent alcohol use and associations with adolescent and adult illicit drug use. | Khan MR et al. | — | 2014 | → |
| Monkeys that voluntarily and chronically drink alcohol damage their brains: a longitudinal MRI study. | Kroenke CD et al. | — | 2014 | → |
| Neuropsychosocial profiles of current and future adolescent alcohol misusers. | Whelan R et al. | — | 2014 | → |
| New research findings since the 2007 Surgeon General's Call to Action to Prevent and Reduce Underage Drinking: a review. | Hingson R et al. | — | 2014 | → |
| The effects of age at the onset of drinking to intoxication and chronic ethanol self-administration in male rhesus macaques. | Helms CM et al. | — | 2014 | → |
| Universal Internet-based prevention for alcohol and cannabis use reduces truancy, psychological distress and moral disengagement: a cluster randomised controlled trial. | Newton NC et al. | — | 2014 | → |
| Validity of brief screening instrument for adolescent tobacco, alcohol, and drug use. | Kelly SM et al. | — | 2014 | → |
| Adolescence and Alcohol: a review of the literature. | Skala K et al. | — | 2013 | → |
| Are there differences between young African-American and European-American women in the relative influences of genetics versus environment on age at first drink and problem alcohol use? | Sartor CE et al. | — | 2013 | → |
| Attitude and risk of substance use in adolescents diagnosed with Asperger syndrome. | Ramos M et al. | — | 2013 | → |
| Causal influence of age at first drink on alcohol involvement in adulthood and its moderation by familial context. | Deutsch AR et al. | — | 2013 | → |
| Intergenerational transmission of drinking motives and how they relate to young adults' alcohol use. | Mares SH et al. | — | 2013 | → |
| Onset to First Alcohol Use in Early Adolescence: A Network Diffusion Model. | Light JM et al. | — | 2013 | → |
| Physician advice to adolescents about drinking and other health behaviors. | Hingson RW et al. | — | 2013 | → |
| Preliminary evidence for a gene-environment interaction in predicting alcohol use disorders in adolescents. | Miranda R et al. | — | 2013 | → |
| Stressful Life Events and Relapse Among Formerly Alcohol Dependent Adults. | Pilowsky DJ et al. | — | 2013 | → |
| The Age of Initiation of Drug Use and Sexual Behavior May Influence Subsequent HIV Risk Behavior: A Systematic Review. | Baldwin P et al. | — | 2013 | → |
| The developmental psychopathology of alcohol use and alcohol disorders: research achievements and future directions. | Chassin L et al. | — | 2013 | → |
| What do you feel? Adolescent drug and alcohol users show altered brain response to pleasant interoceptive stimuli. | Migliorini R et al. | — | 2013 | → |
| Addressing the critical health problem of adolescent substance use through health care, research, and public policy. | Feinstein EC et al. | — | 2012 | → |
| Age at first alcoholic drink as predictor of current HIV sexual risk behaviors among a sample of injection drug users (IDUs) and non-IDUs who are sexual partners of IDUs, in St. Petersburg, Russia. | Abdala N et al. | — | 2012 | → |
| Age of first use and delay to first intoxication in relation to trajectories of heavy drinking and alcohol-related problems during emerging adulthood. | Morean ME et al. | — | 2012 | → |
| Alcohol, tobacco, and prescription drugs: the relationship with illicit drugs in the treatment of substance users. | Teesson M et al. | — | 2012 | → |
| Alcohol use, alcohol problems, and problem behavior engagement among students at two schools in northern Mexico. | Mancha BE et al. | — | 2012 | → |
| ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior. | Chen XD et al. | — | 2012 | → |
| Associations of alcohol, nicotine, cannabis, and drug use/dependence with educational attainment: evidence from cotwin-control analyses. | Grant JD et al. | — | 2012 | → |
| Engaging parents in the family check-up in middle school: longitudinal effects on family conflict and problem behavior through the high school transition. | Van Ryzin MJ et al. | — | 2012 | → |
| Family and peer predictors of substance use from early adolescence to early adulthood: an 11-year prospective analysis. | Van Ryzin MJ et al. | — | 2012 | → |
| Glucocorticoid and polyamine interactions in the plasticity of glutamatergic synapses that contribute to ethanol-associated dependence and neuronal injury. | Prendergast MA et al. | — | 2012 | → |
| Individuality and contextual influences on drug dependence: a 15-year Prospective longitudinal study of adolescents from Harlem. | Brook JS et al. | — | 2012 | → |
| Interventions for adolescent alcohol use. | Chun TH et al. | — | 2012 | → |
| Longitudinal associations between adolescent alcohol use and adulthood sexual risk behavior and sexually transmitted infection in the United States: assessment of differences by race. | Khan MR et al. | — | 2012 | → |
| Parental alcohol-specific rules and alcohol use from early adolescence to young adulthood. | Mares SH et al. | — | 2012 | → |
| Personal and contextual factors in the escalation of driving after drinking across the college years. | Quinn PD et al. | — | 2012 | → |
| Positive and negative effects of alcohol and nicotine and their interactions: a mechanistic review. | Hurley LL et al. | — | 2012 | → |
| Shared genetic contributions to early-onset drinking and drinking to cope motives. | Young-Wolff KC et al. | — | 2012 | → |
| Sustained decreases in risk exposure and youth problem behaviors after installation of the Communities That Care prevention system in a randomized trial. | Hawkins JD et al. | — | 2012 | → |
| The subjective physiological, psychological, and behavioral risk-taking consequences of alcohol and energy drink co-ingestion. | Peacock A et al. | — | 2012 | → |
| Addiction, adolescence, and the integration of control and motivation. | Gladwin TE et al. | — | 2011 | → |
| Alcohol and drug prevention in nightlife settings: a review of experimental studies. | Bolier L et al. | — | 2011 | → |
| A longitudinal twin study of effects of adolescent alcohol abuse on the neurophysiology of attention and orienting. | Koskinen SM et al. | — | 2011 | → |
| A parsimonious, integrative model of key psychological correlates of UK university students' alcohol consumption. | Atwell K et al. | — | 2011 | → |
| Associations of social phobia and general anxiety with alcohol and drug use in a community sample of adolescents. | Fröjd S et al. | — | 2011 | → |
| Correlates of alcohol abuse/dependence in early-onset alcohol-using women. | Jenkins MB et al. | — | 2011 | → |
| Effect of alcohol consumption in prenatal life, childhood, and adolescence on child development. | Foltran F et al. | — | 2011 | → |
| Greater than the Sum of its Parts: The Combined Effect of Early Alcohol Use and Violence on Alcohol Abuse and Violence in Adulthood. | Reingle J et al. | — | 2011 | → |
| Making sense of alcohol experiences: young adolescents' accounts of alcohol-related critical incidents. | Van Hoof JJ et al. | — | 2011 | → |
| Personality correlates of the common and unique variance across conduct disorder and substance misuse symptoms in adolescence. | Castellanos-Ryan N et al. | — | 2011 | → |
| Reporting bias in the association between age at first alcohol use and heavy episodic drinking. | Sartor CE et al. | — | 2011 | → |
| Structural, concurrent, and predictive validity of the Substance Use Risk Profile Scale in early adolescence. | Krank M et al. | — | 2011 | → |
| The influence of behavioural and health problems on alcohol and drug use in late adolescence - a follow up study of 2 399 young Norwegians. | Strandheim A et al. | — | 2011 | → |
| The influence of gene-environment interactions on alcohol consumption and alcohol use disorders: a comprehensive review. | Young-Wolff KC et al. | — | 2011 | → |
| A cotwin-control analysis of drug use and abuse/dependence risk associated with early-onset cannabis use. | Grant JD et al. | — | 2010 | → |
| An animal model of social instability stress in adolescence and risk for drugs of abuse. | McCormick CM | — | 2010 | → |
| Associations between ADH gene variants and alcohol phenotypes in Dutch adults. | van Beek JH et al. | — | 2010 | → |
| Genetic and environmental influences on cannabis use initiation and problematic use: a meta-analysis of twin studies. | Verweij KJ et al. | — | 2010 | → |
| Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genes. | Grucza RA et al. | — | 2010 | → |
| Perception among medical students in Riyadh, Saudi Arabia, regarding alcohol and substance abuse in the community: a cross-sectional survey. | Al-Haqwi AI | — | 2010 | → |
| Problem drinking among young people in Ireland. | Nkire N et al. | — | 2010 | → |
| Trajectories of Substance Use Disorders in Youth: Identifying and Predicting Group Memberships. | Lee CY et al. | — | 2010 | → |
| Validity of a brief screening instrument-CRAFFT in a multiethnic Asian population. | Subramaniam M et al. | — | 2010 | → |
| Adverse childhood events and lifetime alcohol dependence. | Pilowsky DJ et al. | — | 2009 | → |
| Age of drinking onset, alcohol use disorders, frequent heavy drinking, and unintentionally injuring oneself and others after drinking. | Hingson RW et al. | — | 2009 | → |
| Age of drinking onset and injuries, motor vehicle crashes, and physical fights after drinking and when not drinking. | Hingson RW et al. | — | 2009 | → |
| Developmental epidemiology of drug use and abuse in adolescence and young adulthood: Evidence of generalized risk. | Palmer RH et al. | — | 2009 | → |
| Dimensionality of lifetime alcohol abuse, dependence and binge drinking. | Hasin DS et al. | — | 2009 | → |
| Ecology and drug use: universal predictors across time and place. | Brook JS et al. | — | 2009 | → |
| Evidence for an interaction between age at first drink and genetic influences on DSM-IV alcohol dependence symptoms. | Agrawal A et al. | — | 2009 | → |
| Gender differences in factors influencing alcohol use and drinking progression among adolescents. | Schulte MT et al. | — | 2009 | → |
| Impact of age at first drink on vulnerability to alcohol-related problems: testing the marker hypothesis in a prospective study of young adults. | Buchmann AF et al. | — | 2009 | → |
| Long-term effects of minimum drinking age laws on past-year alcohol and drug use disorders. | Norberg KE et al. | — | 2009 | → |
| Substance use and knowledge among Italian high school students. | Spacilova L et al. | — | 2009 | → |
| Timing of first alcohol use and alcohol dependence: evidence of common genetic influences. | Sartor CE et al. | — | 2009 | → |
| Age- and sex-dependent effects of footshock stress on subsequent alcohol drinking and acoustic startle behavior in mice selectively bred for high-alcohol preference. | Chester JA et al. | — | 2008 | → |
| Behavioral disinhibition and the development of early-onset addiction: common and specific influences. | Iacono WG et al. | — | 2008 | → |
| Correspondence between secular changes in alcohol dependence and age of drinking onset among women in the United States. | Grucza RA et al. | — | 2008 | → |
| Early alcohol experiences and adolescent mental health: a population-based study in Taiwan. | Chen CY et al. | — | 2008 | → |
| Family interventions and their effect on adolescent alcohol use in general populations; a meta-analysis of randomized controlled trials. | Smit E et al. | — | 2008 | → |
| Genetic and environmental influences on the rate of progression to alcohol dependence in young women. | Sartor CE et al. | — | 2008 | → |
| Predicting adolescent alcohol drinking patterns after major injury. | Dunn C et al. | — | 2008 | → |
| Severity of alcohol use and problem behaviors among school-based youths in Puerto Rico. | Latimer WW et al. | — | 2008 | → |
| Substance dependence: Decades apart in a teaching hospital. | Venkatesan J et al. | — | 2008 | → |
| Alcohol use and religiousness/spirituality among adolescents. | Knight JR et al. | — | 2007 | → |
| Brain morphometry and cognitive performance in detoxified alcohol-dependents with preserved psychosocial functioning. | Chanraud S et al. | — | 2007 | → |
| Epidemiological patterns of extra-medical drug use in the United States: evidence from the National Comorbidity Survey Replication, 2001-2003. | Degenhardt L et al. | — | 2007 | → |
| Biological processes underlying co-use of alcohol and nicotine: neuronal mechanisms, cross-tolerance, and genetic factors. | Funk D et al. | — | 2006 | → |