Markov chain Monte Carlo segregation and linkage analysis for oligogenic models.
paper
Cited
Public
Unavailable
- Authors
- Heath, S C
- Year
- 1997
- Journal
- American journal of human genetics
- PMID
- 9326339
- DOI
- 10.1086/515506
- PMCID
- PMC1715966
A new method for segregation and linkage analysis, with pedigree data, is described. Reversible jump Markov chain Monte Carlo methods are used to implement a sampling scheme in which the Markov chain can jump between parameter subspaces corresponding to models with different numbers of quantitative-trait loci (QTL's). Joint estimation of QTL number, position, and effects is possible, avoiding the problems that can arise from misspecification of the number of QTL's in a linkage analysis. The method is illustrated by use of a data set simulated for the 9th Genetic Analysis Workshop; this data set had several oligogenic traits, generated by use of a 1,497-member pedigree. The mixing characteristics of the method appear to be good, and the method correctly recovers the simulated model from the test data set. The approach appears to have great potential both for robust linkage analysis and for the answering of more general questions regarding the genetic control of complex traits.
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| Genetic evaluation with major genes and polygenic inheritance when some animals are not genotyped using gene content multiple-trait BLUP. | Legarra A et al. | β | 2015 | β |
| Genetic linkage analysis in the age of whole-genome sequencing. | Ott J et al. | β | 2015 | β |
| Genome-wide genetic investigation of serological measures of common infections. | Rubicz R et al. | β | 2015 | β |
| Genome-wide significant linkage of schizophrenia-related neuroanatomical trait to 12q24. | Sprooten E et al. | β | 2015 | β |
| Next-generation gene discovery for variants of large impact on lipid traits. | Rosenthal E et al. | β | 2015 | β |
| PBAP: a pipeline for file processing and quality control of pedigree data with dense genetic markers. | Nato AQ et al. | β | 2015 | β |
| Pleiotropic locus for emotion recognition and amygdala volume identified using univariate and bivariate linkage. | Knowles EE et al. | β | 2015 | β |
| Replicated analysis of the genetic architecture of quantitative traits in two wild great tit populations. | Santure AW et al. | β | 2015 | β |
| Sequencing strategies and characterization of 721 vervet monkey genomes for future genetic analyses of medically relevant traits. | Huang YS et al. | β | 2015 | β |
| The genetic architecture of sexually selected traits in two natural populations of Drosophila montana. | Veltsos P et al. | β | 2015 | β |
| A novel targeted learning method for quantitative trait loci mapping. | Wang H et al. | β | 2014 | β |
| A statistical framework to guide sequencing choices in pedigrees. | Cheung CY et al. | β | 2014 | β |
| Bayesian QTL analyses using pedigreed families of an outcrossing species, with application to fruit firmness in apple. | Bink MC et al. | β | 2014 | β |
| Challenges and prospects in genome-wide quantitative trait loci mapping of standing genetic variation in natural populations. | Schielzeth H et al. | β | 2014 | β |
| Combined linkage disequilibrium and linkage mapping: Bayesian multilocus approach. | Pikkuhookana P et al. | β | 2014 | β |
| Common genetic variants on 6q24 associated with exceptional episodic memory performance in the elderly. | Barral S et al. | β | 2014 | β |
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| Genetic variants associated with lung function: the long life family study. | Thyagarajan B et al. | β | 2014 | β |
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| A quantitative trait locus analysis of personality in wild bighorn sheep. | Poissant J et al. | β | 2013 | β |
| A system for exact and approximate genetic linkage analysis of SNP data in large pedigrees. | Silberstein M et al. | β | 2013 | β |
| Dosage transmission disequilibrium test (dTDT) for linkage and association detection. | Zhang Z et al. | β | 2013 | β |
| From beavis to beak color: a simulation study to examine how much qtl mapping can reveal about the genetic architecture of quantitative traits. | Slate J | β | 2013 | β |
| Genome scan in familial late-onset Alzheimer's disease: a locus on chromosome 6 contributes to age-at-onset. | Zhao W et al. | β | 2013 | β |
| Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study. | Lee JH et al. | β | 2013 | β |
| Genome-wide association study of personality traits in the long life family study. | Bae HT et al. | β | 2013 | β |
| Genome-wide linkage analysis of carotid artery lumen diameter: the strong heart family study. | Bella JN et al. | β | 2013 | β |
| Genomic dissection of variation in clutch size and egg mass in a wild great tit (Parus major) population. | Santure AW et al. | β | 2013 | β |
| GIGI: an approach to effective imputation of dense genotypes on large pedigrees. | Cheung CY et al. | β | 2013 | β |
| Heritability and preliminary genome-wide linkage analysis of arsenic metabolites in urine. | Tellez-Plaza M et al. | β | 2013 | β |
| Joint linkage and association analysis with exome sequence data implicates SLC25A40 in hypertriglyceridemia. | Rosenthal EA et al. | β | 2013 | β |
| Metaβanalysis of genetic variants associated with human exceptional longevity. | Sebastiani P et al. | β | 2013 | β |
| Modelling QTL effect on BTA06 using random regression test day models. | Suchocki T et al. | β | 2013 | β |
| Nonsyndromic brachydactyly type D and type E mapped to 7p15 in healthy children and adults from the Jirel ethnic group in eastern Nepal. | Williams KD et al. | β | 2013 | β |
| PNPLA3 gene-by-visceral adipose tissue volume interaction and the pathogenesis of fatty liver disease: the NHLBI family heart study. | Graff M et al. | β | 2013 | β |
| QTL mapping of leukocyte telomere length in American Indians: the Strong Heart Family Study. | Zhu Y et al. | β | 2013 | β |
| Quantitative trait locus linkage analysis in a large Amish pedigree identifies novel candidate loci for erythrocyte traits. | Hinckley JD et al. | β | 2013 | β |
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| Statistical genetic analysis of serological measures of common, chronic infections in Alaska Native participants in the GOCADAN study. | Rubicz R et al. | β | 2013 | β |
| SwiftLink: parallel MCMC linkage analysis using multicore CPU and GPU. | Medlar A et al. | β | 2013 | β |
| A variable age of onset segregation model for linkage analysis, with correction for ascertainment, applied to glioma. | Sun X et al. | β | 2012 | β |
| Comprehensive genomic analyses associate UGT8 variants with musical ability in a Mongolian population. | Park H et al. | β | 2012 | β |
| Genome-wide linkage scan for quantitative trait loci underlying normal variation in heel bone ultrasound measures. | Lee M et al. | β | 2012 | β |
| Genome-wide mapping for fatty acid composition and melting point of fat in a purebred Duroc pig population. | Uemoto Y et al. | β | 2012 | β |
| High dimensional endophenotype ranking in the search for major depression risk genes. | Glahn DC et al. | β | 2012 | β |
| Lexical decision as an endophenotype for reading comprehension: an exploration of an association. | Naples A et al. | β | 2012 | β |
| Mapping QTL for fat area ratios and serum leptin concentrations in a Duroc purebred population. | Uemoto Y et al. | β | 2012 | β |
| QTL affecting stress response to crowding in a rainbow trout broodstock population. | Rexroad CE et al. | β | 2012 | β |
| QTL linkage analysis of connected populations using ancestral marker and pedigree information. | Bink MC et al. | β | 2012 | β |
| QTL mapping for sexually dimorphic fitness-related traits in wild bighorn sheep. | Poissant J et al. | β | 2012 | β |
| RWGAIM: an efficient high-dimensional random whole genome average (QTL) interval mapping approach. | Verbyla AP et al. | β | 2012 | β |
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| The endocrine stress response is linked to one specific locus on chromosome 3 in a mouse model based on extremes in trait anxiety. | Gonik M et al. | β | 2012 | β |
| The role of large pedigrees in an era of high-throughput sequencing. | Wijsman EM | β | 2012 | β |
| Variants in CPT1A, FADS1, and FADS2 are Associated with Higher Levels of Estimated Plasma and Erythrocyte Delta-5 Desaturases in Alaskan Eskimos. | Voruganti VS et al. | β | 2012 | β |
| A genome-wide linkage scan for quantitative trait loci influencing the craniofacial complex in humans (Homo sapiens sapiens). | Sherwood RJ et al. | β | 2011 | β |
| An alternative model for quantitative trait loci (QTL) analysis in general pedigrees. | Basu S et al. | β | 2011 | β |
| A QTL for genotype by sex interaction for anthropometric measurements in Alaskan Eskimos (GOCADAN Study) on chromosome 19q12-13. | Voruganti VS et al. | β | 2011 | β |
| Confirmation of two quantitative trait loci regions for nematode resistance in commercial British terminal sire breeds. | Matika O et al. | β | 2011 | β |
| Estimation and visualization of identity-by-descent within pedigrees simplifies interpretation of complex trait analysis. | Marchani EE et al. | β | 2011 | β |
| Evaluation of a fibrillin 2 gene haplotype associated with hip dysplasia and incipient osteoarthritis in dogs. | Friedenberg SG et al. | β | 2011 | β |
| Fast, exact linkage analysis for categorical traits on arbitrary pedigree designs. | Brisbin A et al. | β | 2011 | β |
| Fine mapping and replication of QTL in outbred chicken advanced intercross lines. | Besnier F et al. | β | 2011 | β |
| Genetical genomics of Th1 and Th2 immune response in a baboon model of atherosclerosis risk factors. | Vinson A et al. | β | 2011 | β |
| Genetic mapping of vascular calcified plaque loci on chromosome 16p in European Americans from the diabetes heart study. | Lehtinen AB et al. | β | 2011 | β |
| Genetic variability of transcript abundance in pig peri-mortem skeletal muscle: eQTL localized genes involved in stress response, cell death, muscle disorders and metabolism. | Liaubet L et al. | β | 2011 | β |
| Genome scan for spelling deficits: effects of verbal IQ on models of transmission and trait gene localization. | Rubenstein K et al. | β | 2011 | β |
| Genome scan of age-at-onset in the NIMH Alzheimer disease sample uncovers multiple loci, along with evidence of both genetic and sample heterogeneity. | Choi Y et al. | β | 2011 | β |
| Genome scan of clot lysis time and its association with thrombosis in a proteinΒ C-deficient kindred. | Meltzer ME et al. | β | 2011 | β |
| Genome-wide linkage analysis of hemodynamic parameters under mental and physical stress in extended Omani Arab pedigrees: the Oman Family Study. | Hassan MO et al. | β | 2011 | β |
| Genome-wide linkage screen for systolic blood pressure in the Veterans Administration Genetic Epidemiology Study (VAGES) of Mexican-Americans and confirmation of a major susceptibility locus on chromosome 6q14.1. | Puppala S et al. | β | 2011 | β |
| Genome-wide mapping and identification of new quantitative trait loci affecting meat production, meat quality, and carcass traits within a Duroc purebred population. | Soma Y et al. | β | 2011 | β |
| Identity by descent estimation with dense genome-wide genotype data. | Han L et al. | β | 2011 | β |
| Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypes. | Carless MA et al. | β | 2011 | β |
| Joint analysis of quantitative trait loci and major-effect causative mutations affecting meat quality and carcass composition traits in pigs. | Cherel P et al. | β | 2011 | β |
| Linkage and association of phospholipid transfer protein activity to LASS4. | Rosenthal EA et al. | β | 2011 | β |
| Modeling of identity-by-descent processes along a chromosome between haplotypes and their genotyped ancestors. | Druet T et al. | β | 2011 | β |
| Modifier locus of the skeletal muscle involvement in Emery-Dreifuss muscular dystrophy. | Granger B et al. | β | 2011 | β |
| Multivariate linkage scan for metabolic syndrome traits in families with type 2 diabetes. | Edwards KL et al. | β | 2011 | β |
| QTL mapping in outbred half-sib families using Bayesian model selection. | Fang M et al. | β | 2011 | β |
| Quality control issues and the identification of rare functional variants with next-generation sequencing data. | Hemmelmann C et al. | β | 2011 | β |
| Successful identification of rare variants using oligogenic segregation analysis as a prioritizing tool for whole-exome sequencing studies. | Gagnon F et al. | β | 2011 | β |
| The structure of genetic linkage data: from LIPED to 1M SNPs. | Thompson E | β | 2011 | β |
| TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort. | van der Zee J et al. | β | 2011 | β |
| Accounting for disease model uncertainty in mapping heterogeneous traits--a Bayesian model averaging approach. | Biswas S et al. | β | 2010 | β |
| A gene frequency model for QTL mapping using Bayesian inference. | He W et al. | β | 2010 | β |
| A genome scan for quantitative trait loci influencing carcass, post-natal growth and reproductive traits in commercial Angus cattle. | McClure MC et al. | β | 2010 | β |
| A genome-wide scan for tying-up syndrome in Japanese Thoroughbreds. | Tozaki T et al. | β | 2010 | β |
| A likelihood-based trait-model-free approach for linkage detection of binary trait. | Basu S et al. | β | 2010 | β |
| A multi-stage multi-design strategy provides strong evidence that the BAI3 locus is associated with early-onset venous thromboembolism. | Antoni G et al. | β | 2010 | β |
| A quantitative trait locus on chromosome 5p influences d-dimer levels in the san antonio family heart study. | Diego VP et al. | β | 2010 | β |
| A two-stage approximation for analysis of mixture genetic models in large pedigrees. | Habier D et al. | β | 2010 | β |
| Bayesian linkage analysis of categorical traits for arbitrary pedigree designs. | Brisbin A et al. | β | 2010 | β |
| Bayesian model averaging for evaluation of candidate gene effects. | Wu XL et al. | β | 2010 | β |
| Chemerin, a novel adipokine in the regulation of angiogenesis. | Bozaoglu K et al. | β | 2010 | β |
| Confirmation and refinement of a QTL on BTA5 affecting milk production traits in the Fleckvieh dual purpose cattle breed. | Awad A et al. | β | 2010 | β |
| Evidence for three loci modifying age-at-onset of Alzheimer's disease in early-onset PSEN2 families. | Marchani EE et al. | β | 2010 | β |
| Evidence of major genes affecting resistance to bacterial cold water disease in rainbow trout using Bayesian methods of segregation analysis. | Vallejo RL et al. | β | 2010 | β |
| Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects. | Dastani Z et al. | β | 2010 | β |
| Genetics of microstructure of cerebral white matter using diffusion tensor imaging. | Kochunov P et al. | β | 2010 | β |
| Genetic variation at the FTO locus influences RBL2 gene expression. | Jowett JB et al. | β | 2010 | β |
| Genetic variation in APOJ, LPL, and TNFRSF10B affects plasma fatty acid distribution in Alaskan Eskimos. | Voruganti VS et al. | β | 2010 | β |
| Genome-wide evaluation for quantitative trait loci under the variance component model. | Han L et al. | β | 2010 | β |
| Genome-wide linkage analysis for ocular and nasal anthropometric traits in a Mongolian population. | Im SW et al. | β | 2010 | β |
| Horn type and horn length genes map to the same chromosomal region in Soay sheep. | Johnston SE et al. | β | 2010 | β |
| Identity-by-descent matrix decomposition using latent ancestral allele models. | ter Braak CJ et al. | β | 2010 | β |
| Improved IBD detection using incomplete haplotype information. | Genovese G et al. | β | 2010 | β |
| Joint linkage and segregation analysis under multiallelic trait inheritance: simplifying interpretations for complex traits. | Rosenthal EA et al. | β | 2010 | β |
| Linkage and association analyses identify a candidate region for apoB level on chromosome 4q32.3 in FCHL families. | Wijsman EM et al. | β | 2010 | β |
| Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene. | Johansson A et al. | β | 2010 | β |
| Mapping quantitative trait loci in a wild population using linkage and linkage disequilibrium analyses. | HernΓ‘ndez-SΓ‘nchez J et al. | β | 2010 | β |
| Mixed model approaches for the identification of QTLs within a maize hybrid breeding program. | van Eeuwijk FA et al. | β | 2010 | β |
| Molecular basis of a linkage peak: exome sequencing and family-based analysis identify a rare genetic variant in the ADIPOQ gene in the IRAS Family Study. | Bowden DW et al. | β | 2010 | β |
| MQScore_SNP software for multipoint parametric linkage analysis of quantitative traits in large pedigrees. | Axenovich TI et al. | β | 2010 | β |
| Power of competing strategies of linkage analysis for complex traits. | Ma J et al. | β | 2010 | β |
| Refined QTLs of osteoporosis-related traits by linkage analysis with genome-wide SNPs: Framingham SHARe. | Karasik D et al. | β | 2010 | β |
| Two-dimensional, sex-specific autosomal linkage scan of the number of sodium pump sites. | Hasstedt SJ et al. | β | 2010 | β |
| A framework for analyzing both linkage and association: an analysis of Genetic Analysis Workshop 16 simulated data. | Daw EW et al. | β | 2009 | β |
| Analysis of genetic and non-genetic factors that affect the QTc interval in a Mongolian population: the GENDISCAN study. | Im SW et al. | β | 2009 | β |
| Analysis of genetic variability and whole genome linkage of whole-brain, subcortical, and ependymal hyperintense white matter volume. | Kochunov P et al. | β | 2009 | β |
| An efficient algorithm to compute marginal posterior genotype probabilities for every member of a pedigree with loops. | Totir LR et al. | β | 2009 | β |
| A quantitative trait locus for SBP maps near KCNB1 and PTGIS in a population isolate. | BarbaliΔ M et al. | β | 2009 | β |
| A web application to perform linkage disequilibrium and linkage analyses on a computational grid. | HernΓ‘ndez-SΓ‘nchez J et al. | β | 2009 | β |
| Bayesian composite model space approach for mapping quantitative trait Loci in variance component model. | Fang M et al. | β | 2009 | β |
| Bayesian quantitative trait locus mapping based on reconstruction of recent genetic histories. | Gasbarra D et al. | β | 2009 | β |
| Bivariate genome-wide linkage analysis of femoral bone traits and leg lean mass: Framingham study. | Karasik D et al. | β | 2009 | β |
| Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis. | Johansson A et al. | β | 2009 | β |
| Contrasting identity-by-descent estimators, association studies, and linkage analyses using the Framingham Heart Study data. | Marchani EE et al. | β | 2009 | β |
| Correcting for relatedness in Bayesian models for genomic data association analysis. | Pikkuhookana P et al. | β | 2009 | β |
| Deviance Information Criterion (DIC) in Bayesian Multiple QTL Mapping. | Shriner D et al. | β | 2009 | β |
| Genetic and non-genetic correlates of vitamins K and D. | Shea MK et al. | β | 2009 | β |
| Genetic influence on variation in serum uric acid in American Indians: the strong heart family study. | Voruganti VS et al. | β | 2009 | β |
| Genome-wide association and linkage analysis of quantitative traits: comparison of likelihood-ratio test and conditional score statistic. | Hendricks AE et al. | β | 2009 | β |
| Genome-wide linkage scan for genes influencing plasma triglyceride levels in the Veterans Administration Genetic Epidemiology Study. | Coletta DK et al. | β | 2009 | β |
| Genome-wide linkage scan for plasma high density lipoprotein cholesterol, apolipoprotein A-1 and triglyceride variation among American Indian populations: the Strong Heart Family Study. | Li X et al. | β | 2009 | β |
| Genomic selection using low-density marker panels. | Habier D et al. | β | 2009 | β |
| Genotype imputation. | Li Y et al. | β | 2009 | β |
| Haplotyping methods for pedigrees. | Gao G et al. | β | 2009 | β |
| Human QTL linkage mapping. | Almasy L et al. | β | 2009 | β |
| Linear models for joint association and linkage QTL mapping. | Legarra A et al. | β | 2009 | β |
| Linkage analysis of albuminuria. | Mottl AK et al. | β | 2009 | β |
| Mapping quantitative traits in unselected families: algorithms and examples. | Dupuis J et al. | β | 2009 | β |
| Mother's genome or maternally-inherited genes acting in the fetus influence gestational age in familial preterm birth. | Plunkett J et al. | β | 2009 | β |
| PedStr software for cutting large pedigrees for haplotyping, IBD computation and multipoint linkage analysis. | Kirichenko AV et al. | β | 2009 | β |
| Precision of genetic parameters and breeding values estimated in marker assisted BLUP genetic evaluation. | Neuner S et al. | β | 2009 | β |
| Principal component and linkage analysis of cardiovascular risk traits in the Norfolk isolate. | Cox HC et al. | β | 2009 | β |
| PRKCA: a positional candidate gene for body mass index and asthma. | Murphy A et al. | β | 2009 | β |
| Quantitative trait locus on chromosome 1q influences bone loss in young Mexican American adults. | Shaffer JR et al. | β | 2009 | β |
| Same or different? Insights into the etiology of phonological awareness and rapid naming. | Naples AJ et al. | β | 2009 | β |
| Suggestive linkage detected for blood pressure related traits on 2q and 22q in the population on the Samoan islands. | Aberg K et al. | β | 2009 | β |
| Susceptibility loci for adiposity phenotypes on 8p, 9p, and 16q in American Samoa and Samoa. | Aberg K et al. | β | 2009 | β |
| A Bayesian method for simultaneously detecting Mendelian and imprinted quantitative trait loci in experimental crosses of outbred species. | Hayashi T et al. | β | 2008 | β |
| A genome scan to detect quantitative trait loci for economically important traits in Holstein cattle using two methods and a dense single nucleotide polymorphism map. | Daetwyler HD et al. | β | 2008 | β |
| A genomewide linkage scan for quantitative trait loci influencing the craniofacial complex in baboons (Papio hamadryas spp.). | Sherwood RJ et al. | β | 2008 | β |
| A genome-wide linkage scan identifies multiple chromosomal regions influencing serum lipid levels in the population on the Samoan islands. | Aberg K et al. | β | 2008 | β |
| A genome wide linkage scan of metacarpal size and geometry in the Framingham Study. | Karasik D et al. | β | 2008 | β |
| A genome-wide linkage study in families with major depression and co-morbid unexplained swelling. | Anderson CA et al. | β | 2008 | β |
| Analysis of quantitative trait loci. | Falchi M | β | 2008 | β |
| An approach for cutting large and complex pedigrees for linkage analysis. | Liu F et al. | β | 2008 | β |
| A pleiotropic QTL on 2p influences serum Lp-PLA2 activity and LDL cholesterol concentration in a baboon model for the genetics of atherosclerosis risk factors. | Vinson A et al. | β | 2008 | β |
| Autosome-wide linkage analysis of hip structural phenotypes in the Old Order Amish. | Streeten EA et al. | β | 2008 | β |
| A whole genome linkage scan identifies multiple chromosomal regions influencing adiposity-related traits among Samoans. | Dai F et al. | β | 2008 | β |
| Breaking loops in large complex pedigrees. | Axenovich TI et al. | β | 2008 | β |
| Calculation of IBD probabilities with dense SNP or sequence data. | Keith JM et al. | β | 2008 | β |
| Circulating soluble ICAM-1 levels shows linkage to ICAM gene cluster region on chromosome 19: the NHLBI Family Heart Study follow-up examination. | Bielinski SJ et al. | β | 2008 | β |
| Clinical and genetic correlates of soluble P-selectin in the community. | Lee DS et al. | β | 2008 | β |
| Contemporary model-free methods for linkage analysis. | Almasy L et al. | β | 2008 | β |
| Cross-species replication of a resistin mRNA QTL, but not QTLs for circulating levels of resistin, in human and baboon. | Tejero ME et al. | β | 2008 | β |
| Empirical significance values for linkage analysis: trait simulation using posterior model distributions from MCMC oligogenic segregation analysis. | Igo RP et al. | β | 2008 | β |
| Exact trait-model-free tests for linkage detection in pedigrees. | Basu S et al. | β | 2008 | β |
| Genetic epidemiology of subclinical cardiovascular disease in the diabetes heart study. | Bowden DW et al. | β | 2008 | β |
| Genetic influences on bone loss in the San Antonio Family Osteoporosis study. | Shaffer JR et al. | β | 2008 | β |
| Genome scan of a nonword repetition phenotype in families with dyslexia: evidence for multiple loci. | Brkanac Z et al. | β | 2008 | β |
| Genome-wide linkage scan for loci of musical aptitude in Finnish families: evidence for a major locus at 4q22. | Pulli K et al. | β | 2008 | β |
| Genome-wide linkage scans for renal function and albuminuria in Type 2 diabetes mellitus: the Diabetes Heart Study. | Freedman BI et al. | β | 2008 | β |
| Genome-wide scan revealed genetic loci for energy metabolism in Hispanic children and adolescents. | Cai G et al. | β | 2008 | β |
| Genotype-by-diet effects on co-variation in Lp-PLA2 activity and LDL-cholesterol concentration in baboons fed an atherogenic diet. | Vinson A et al. | β | 2008 | β |
| Heritability of refractive value and ocular biometrics. | Paget S et al. | β | 2008 | β |
| Identifying modifier loci in existing genome scan data. | Daw EW et al. | β | 2008 | β |
| Identity-by-descent estimation and mapping of qualitative traits in large, complex pedigrees. | Abney M | β | 2008 | β |
| Linkage analysis of glomerular filtration rate in American Indians. | Mottl AK et al. | β | 2008 | β |
| Linkage mapping of CVD risk traits in the isolated Norfolk Island population. | Bellis C et al. | β | 2008 | β |
| Linkage study of fibrinogen levels: the Strong Heart Family Study. | Best LG et al. | β | 2008 | β |
| Localization of multiple quantitative trait loci influencing susceptibility to infection with Ascaris lumbricoides. | Williams-Blangero S et al. | β | 2008 | β |
| Multilocus lod scores in large pedigrees: combination of exact and approximate calculations. | Tong L et al. | β | 2008 | β |
| Presentation, heritability, and genome-wide linkage analysis of the midchildhood growth spurt in healthy children from the Fels Longitudinal Study. | Towne B et al. | β | 2008 | β |
| Quantitative trait loci analysis on Sus scrofa chromosome 7 for meat production, meat quality, and carcass traits within a Duroc purebred population. | Uemoto Y et al. | β | 2008 | β |
| Sampling genotype configurations in a large complex pedigree. | Szydlowski M et al. | β | 2008 | β |
| Single nucleotide polymorphisms refine QTL intervals for hip joint laxity in dogs. | Zhu L et al. | β | 2008 | β |
| Two quantitative trait loci influence whipworm (Trichuris trichiura) infection in a Nepalese population. | Williams-Blangero S et al. | β | 2008 | β |
| Accounting for epistasis in linkage analysis of general pedigrees. | Sung YJ et al. | β | 2007 | β |
| A general and efficient method for estimating continuous IBD functions for use in genome scans for QTL. | Besnier F et al. | β | 2007 | β |
| A genome-wide linkage scan for iron phenotype quantitative trait loci: the HEIRS Family Study. | Acton RT et al. | β | 2007 | β |
| A genome-wide linkage scan of insulin level derived traits: the Amish Family Diabetes Study. | Hsueh WC et al. | β | 2007 | β |
| An efficient Bayesian model selection approach for interacting quantitative trait loci models with many effects. | Yi N et al. | β | 2007 | β |
| A novel obesity locus on chromosome 4q: the Strong Heart Family Study. | Almasy L et al. | β | 2007 | β |
| Ascertainment correction for Markov chain Monte Carlo segregation and linkage analysis of a quantitative trait. | Ma J et al. | β | 2007 | β |
| Bayesian association mapping of multiple quantitative trait loci and its application to the analysis of genetic variation among Oryza sativa L. germplasms. | Iwata H et al. | β | 2007 | β |
| Bayesian shrinkage analysis of quantitative trait Loci for dynamic traits. | Yang R et al. | β | 2007 | β |
| Bivariate linkage study of proximal hip geometry and body size indices: the Framingham study. | Karasik D et al. | β | 2007 | β |
| Circulating MCP-1 levels shows linkage to chemokine receptor gene cluster on chromosome 3: the NHLBI family heart study follow-up examination. | Bielinski SJ et al. | β | 2007 | β |
| Comparison of multipoint linkage analyses for quantitative traits in the CEPH data: parametric LOD scores, variance components LOD scores, and Bayes factors. | Sung YJ et al. | β | 2007 | β |
| Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes. | GΓΆring HH et al. | β | 2007 | β |
| Estimating genealogies from linked marker data: a Bayesian approach. | Gasbarra D et al. | β | 2007 | β |
| Genetic determinants of mitochondrial content. | Curran JE et al. | β | 2007 | β |
| Genome-wide linkage analysis of pulmonary function in families of children with asthma in Costa Rica. | Hersh CP et al. | β | 2007 | β |
| Genome-wide mapping of modifier chromosomal loci for human hypertrophic cardiomyopathy. | Daw EW et al. | β | 2007 | β |
| Genome-wide scan for adiposity-related phenotypes in adults from American Samoa. | Dai F et al. | β | 2007 | β |
| Genome-wide scan for serum ghrelin detects linkage on chromosome 1p36 in Hispanic children: results from the Viva La Familia study. | Voruganti VS et al. | β | 2007 | β |
| Genotype x adiposity interaction linkage analyses reveal a locus on chromosome 1 for lipoprotein-associated phospholipase A2, a marker of inflammation and oxidative stress. | Diego VP et al. | β | 2007 | β |
| Identification of promoter variants in baboon endothelial lipase that regulate high-density lipoprotein cholesterol levels. | Cox LA et al. | β | 2007 | β |
| Identification of two novel quantitative trait loci for pre-eclampsia susceptibility on chromosomes 5q and 13q using a variance components-based linkage approach. | Johnson MP et al. | β | 2007 | β |
| Increasing the efficiency of variance component quantitative trait loci analysis by using reduced-rank identity-by-descent matrices. | RΓΆnnegΓ₯rd L et al. | β | 2007 | β |
| Linkage analysis for three coagulation factors clustering on chromosome 13q34: factor VII, factor X and protein Z. | Vossen CY et al. | β | 2007 | β |
| Linkage analysis of a cluster-based quantitative phenotype constructed from pulmonary function test data in 27 multigenerational families with multiple asthmatic members. | Reilly C et al. | β | 2007 | β |
| Linkage analysis of circulating levels of adiponectin in Hispanic children. | Tejero ME et al. | β | 2007 | β |
| Linkage and association analyses of principal components in expression data. | Hinrichs AL et al. | β | 2007 | β |
| Mapping of a quantitative trait locus for resistance against infectious salmon anaemia in Atlantic salmon (Salmo salar): comparing survival analysis with analysis on affected/resistant data. | Moen T et al. | β | 2007 | β |
| Mapping quantitative trait Loci underlying fitness-related traits in a free-living sheep population. | Beraldi D et al. | β | 2007 | β |
| MCMC-based linkage analysis for complex traits on general pedigrees: multipoint analysis with a two-locus model and a polygenic component. | Sung YJ et al. | β | 2007 | β |
| Proximal hip geometry is linked to several chromosomal regions: genome-wide linkage results from the Framingham Osteoporosis Study. | Demissie S et al. | β | 2007 | β |
| Quantitative trait loci for peripheral blood cell counts: a study in baboons. | Bertin A et al. | β | 2007 | β |
| Quantitative trait loci (QTL) mapping of resistance to strongyles and coccidia in the free-living Soay sheep (Ovis aries). | Beraldi D et al. | β | 2007 | β |
| Separation of base allele and sampling term effects gives new insights in variance component QTL analysis. | RΓΆnnegΓ₯rd L et al. | β | 2007 | β |
| Sex-specific linkage to total serum immunoglobulin E in families of children with asthma in Costa Rica. | Raby BA et al. | β | 2007 | β |
| Significant linkage to airway responsiveness on chromosome 12q24 in families of children with asthma in Costa Rica. | CeledΓ³n JC et al. | β | 2007 | β |
| Summary of Genetic Analysis Workshop 15: Group 9 linkage analysis of the CEPH expression data. | Wijsman EM et al. | β | 2007 | β |
| The advantages of dense marker sets for linkage analysis with very large families. | Thomson R et al. | β | 2007 | β |
| The feasibility of oligogenic combined segregation and linkage analysis in CEPH pedigrees. | Daw EW et al. | β | 2007 | β |
| The locus for bovine dilated cardiomyopathy maps to chromosome 18. | Guziewicz KE et al. | β | 2007 | β |
| Towards linkage analysis with markers in linkage disequilibrium by graphical modelling. | Thomas A | β | 2007 | β |
| A genome search for genetic determinants of markers of protein C activation. | Vossen CY et al. | β | 2006 | β |
| A genome-wide linkage scan for genes controlling variation in renal function estimated by serum cystatin C levels in extended families with type 2 diabetes. | Placha G et al. | β | 2006 | β |
| A genome-wide linkage scan for genes controlling variation in urinary albumin excretion in type II diabetes. | Krolewski AS et al. | β | 2006 | β |
| A novel framework for sib pair linkage analysis. | Poznik GD et al. | β | 2006 | β |
| A quantitative trait locus on chromosome 18q for physical activity and dietary intake in Hispanic children. | Cai G et al. | β | 2006 | β |
| A quantitative trait locus (QTL) on chromosome 6q influences birth weight in two independent family studies. | Arya R et al. | β | 2006 | β |
| Chromosome-wise dissection of the genome of the extremely big mouse line DU6i. | Bevova MR et al. | β | 2006 | β |
| Development of a linkage map and mapping of phenotypic polymorphisms in a free-living population of Soay sheep (Ovis aries). | Beraldi D et al. | β | 2006 | β |
| Evidence for multiple loci from a genome scan of autism kindreds. | Schellenberg GD et al. | β | 2006 | β |
| Examination of a region showing linkage map discrepancies across sheep breeds. | McRae AF et al. | β | 2006 | β |
| Fasting insulin and obesity-related phenotypes are linked to chromosome 2p: the Strong Heart Family Study. | Diego VP et al. | β | 2006 | β |
| Finding consistent gene transmission patterns on large and complex pedigrees. | Pirinen M et al. | β | 2006 | β |
| Functional mapping - how to map and study the genetic architecture of dynamic complex traits. | Wu R et al. | β | 2006 | β |
| Genetic factors modifying clinical expression of autosomal dominant RP. | Daiger SP et al. | β | 2006 | β |
| Genetic mapping of a 17q chromosomal region linked to obesity phenotypes in the IRAS family study. | Sutton BS et al. | β | 2006 | β |
| Genetic mapping of disposition index and acute insulin response loci on chromosome 11q. The Insulin Resistance Atherosclerosis Study (IRAS) Family Study. | Palmer ND et al. | β | 2006 | β |
| Genome-wide linkage of plasma adiponectin reveals a major locus on chromosome 3q distinct from the adiponectin structural gene: the IRAS family study. | Guo X et al. | β | 2006 | β |
| Genomewide scan for real-word reading subphenotypes of dyslexia: novel chromosome 13 locus and genetic complexity. | Igo RP et al. | β | 2006 | β |
| Heritability and linkage analysis of hand, foot, and eye preference in Mexican Americans. | Warren DM et al. | β | 2006 | β |
| Linkage analysis of LDL cholesterol in American Indian populations: the Strong Heart Family Study. | North KE et al. | β | 2006 | β |
| Linkage analysis of quantitative traits for obesity, diabetes, hypertension, and dyslipidemia on the island of Kosrae, Federated States of Micronesia. | Shmulewitz D et al. | β | 2006 | β |
| Multipoint linkage analysis with many multiallelic or dense diallelic markers: Markov chain-Monte Carlo provides practical approaches for genome scans on general pedigrees. | Wijsman EM et al. | β | 2006 | β |
| Parallel computations on pedigree data through mapping to configurable computing devices. | Henshall JM et al. | β | 2006 | β |
| Quantitative trait loci for BMD identified by autosome-wide linkage scan to chromosomes 7q and 21q in men from the Amish Family Osteoporosis Study. | Streeten EA et al. | β | 2006 | β |
| Segregation analysis of a complex quantitative trait: approaches for identifying influential data points. | Igo RP et al. | β | 2006 | β |
| Simultaneous fine mapping of multiple closely linked quantitative trait Loci using combined linkage disequilibrium and linkage with a general pedigree. | Lee SH et al. | β | 2006 | β |
| Study on mapping quantitative trait loci for animal complex binary traits using Bayesian-Markov chain Monte Carlo approach. | Liu J et al. | β | 2006 | β |
| Using sex-averaged genetic maps in multipoint linkage analysis when identity-by-descent status is incompletely known. | Fingerlin TE et al. | β | 2006 | β |
| A comparison of univariate, bivariate, and trivariate whole-genome linkage screens of genetically correlated electrophysiological endophenotypes. | Warren DM et al. | β | 2005 | β |
| A genetic and epidemiologic study of cardiovascular disease in Alaska natives (GOCADAN): design and methods. | Howard BV et al. | β | 2005 | β |
| A genome scan for fasting insulin and fasting glucose identifies a quantitative trait locus on chromosome 17p: the insulin resistance atherosclerosis study (IRAS) family study. | Rich SS et al. | β | 2005 | β |
| A genome scan in multigenerational families with dyslexia: Identification of a novel locus on chromosome 2q that contributes to phonological decoding efficiency. | Raskind WH et al. | β | 2005 | β |
| A Monte Carlo algorithm for computing the IBD matrices using incomplete marker information. | Mao Y et al. | β | 2005 | β |
| A novel Markov chain monte carlo approach for constructing accurate meiotic maps. | George AW | β | 2005 | β |
| APOE and other loci affect age-at-onset in Alzheimer's disease families with PS2 mutation. | Wijsman EM et al. | β | 2005 | β |
| Approximating identity-by-descent matrices using multiple haplotype configurations on pedigrees. | Gao G et al. | β | 2005 | β |
| A single nucleotide polymorphism in MGEA5 encoding O-GlcNAc-selective N-acetyl-beta-D glucosaminidase is associated with type 2 diabetes in Mexican Americans. | Lehman DM et al. | β | 2005 | β |
| Bayesian mapping of QTL in outbred F2 families allowing inference about whether F0 grandparents are homozygous or heterozygous at QTL. | Hayashi T et al. | β | 2005 | β |
| Bayesian model selection for genome-wide epistatic quantitative trait loci analysis. | Yi N et al. | β | 2005 | β |
| Bayesian shrinkage estimation of quantitative trait loci parameters. | Wang H et al. | β | 2005 | β |
| Combining the meiosis Gibbs sampler with the random walk approach for linkage and association studies with a general complex pedigree and multimarker loci. | Lee SH et al. | β | 2005 | β |
| Comparison of marker types and map assumptions using Markov chain Monte Carlo-based linkage analysis of COGA data. | Sieh W et al. | β | 2005 | β |
| Determinants of variation in serum paraoxonase enzyme activity in baboons. | Rainwater DL et al. | β | 2005 | β |
| Estimation of quantitative trait loci parameters for milk production traits in German Holstein dairy cattle population. | Szyda J et al. | β | 2005 | β |
| Evidence for a novel glaucoma locus at chromosome 3p21-22. | Baird PN et al. | β | 2005 | β |
| Fine-mapping milk production quantitative trait loci on BTA6: analysis of the bovine osteopontin gene. | Schnabel RD et al. | β | 2005 | β |
| Genetic study of ICAM1 in clinical malaria in Senegal. | Ndiaye R et al. | β | 2005 | β |
| Genome scan for quantitative trait loci influencing HDL levels: evidence for multilocus inheritance in familial combined hyperlipidemia. | Gagnon F et al. | β | 2005 | β |
| Genome-wide linkage analyses of type 2 diabetes in Mexican Americans: the San Antonio Family Diabetes/Gallbladder Study. | Hunt KJ et al. | β | 2005 | β |
| Genome-wide scans for heritability of fasting serum insulin and glucose concentrations in hypertensive families. | Freedman BI et al. | β | 2005 | β |
| Genome-wide search for genes affecting serum uric acid levels: the Framingham Heart Study. | Yang Q et al. | β | 2005 | β |
| Inheritance of total serum IgE in the isolated Tangier Island population from Virginia: complexities associated with genealogical depth of pedigrees in segregation analyses. | Mathias RA et al. | β | 2005 | β |
| Joint multi-population analysis for genetic linkage of bipolar disorder or "wellness" to chromosome 4p. | Visscher PM et al. | β | 2005 | β |
| Linkage analysis of factors underlying insulin resistance: Strong Heart Family Study. | North KE et al. | β | 2005 | β |
| Linkage mapping methods applied to the COGA data set: presentation Group 4 of Genetic Analysis Workshop 14. | Daw EW et al. | β | 2005 | β |
| Mapping quantitative trait loci using naturally occurring genetic variance among commercial inbred lines of maize (Zea mays L.). | Zhang YM et al. | β | 2005 | β |
| MCMC multilocus lod scores: application of a new approach. | George AW et al. | β | 2005 | β |
| Multipoint identity-by-descent computations for single-point polymorphism and microsatellite maps. | Hinrichs AL et al. | β | 2005 | β |
| Quantitative founder-effect analysis of French Canadian families identifies specific loci contributing to metabolic phenotypes of hypertension. | Hamet P et al. | β | 2005 | β |
| Single-nucleotide polymorphism versus microsatellite markers in a combined linkage and segregation analysis of a quantitative trait. | Daw EW et al. | β | 2005 | β |
| Software for quantitative trait analysis. | Almasy L et al. | β | 2005 | β |
| Statistical tools for linkage analysis and genetic association studies. | Forabosco P et al. | β | 2005 | β |
| The quantitative trait linkage disequilibrium test: a more powerful alternative to the quantitative transmission disequilibrium test for use in the absence of population stratification. | Havill LM et al. | β | 2005 | β |
| The role of pedigree information in combined linkage disequilibrium and linkage mapping of quantitative trait loci in a general complex pedigree. | Lee SH et al. | β | 2005 | β |
| Whole-genome scan to detect QTL for milk production, conformation, fertility and functional traits in two US Holstein families. | Schnabel RD et al. | β | 2005 | β |
| A genomewide search using an original pairwise sampling approach for large genealogies identifies a new locus for total and low-density lipoprotein cholesterol in two genetically differentiated isolates of Sardinia. | Falchi M et al. | β | 2004 | β |
| A transmission disequilibrium test for general pedigrees that is robust to the presence of random genotyping errors and any number of untyped parents. | Gordon D et al. | β | 2004 | β |
| A unified Markov chain Monte Carlo framework for mapping multiple quantitative trait loci. | Yi N | β | 2004 | β |
| Bayesian point estimation of quantitative trait loci. | Sisson SA et al. | β | 2004 | β |
| Evidence for a novel late-onset Alzheimer disease locus on chromosome 19p13.2. | Wijsman EM et al. | β | 2004 | β |
| Joint oligogenic segregation and linkage analysis using bayesian Markov chain Monte Carlo methods. | Wijsman EM et al. | β | 2004 | β |
| Linkage analyses of four regions previously implicated in dyslexia: confirmation of a locus on chromosome 15q. | Chapman NH et al. | β | 2004 | β |
| Low-density lipoprotein particle size loci in familial combined hyperlipidemia: evidence for multiple loci from a genome scan. | Badzioch MD et al. | β | 2004 | β |
| Mapping multiple quantitative trait Loci for ordinal traits. | Yi N et al. | β | 2004 | β |
| Modifying the Schwarz Bayesian information criterion to locate multiple interacting quantitative trait loci. | Bogdan M et al. | β | 2004 | β |
| On the Metropolis-Hastings acceptance probability to add or drop a quantitative trait locus in Markov chain Monte Carlo-based Bayesian analyses. | Jannink JL et al. | β | 2004 | β |
| Quantitative trait loci (QTL) detection in multicross inbred designs: recovering QTL identical-by-descent status information from marker data. | Crepieux S et al. | β | 2004 | β |
| Replication in genetic studies of complex traits. | SillanpÀÀ MJ et al. | β | 2004 | β |
| Age-of-onset of hypertension vs. a single measurement of systolic blood pressure in a combined linkage and segregation analysis. | Daw EW et al. | β | 2003 | β |
| Approaches to mapping genetically correlated complex traits. | George AW et al. | β | 2003 | β |
| A score for Bayesian genome screening. | Daw EW et al. | β | 2003 | β |
| Bayesian analysis of multilocus association in quantitative and qualitative traits. | Kilpikari R et al. | β | 2003 | β |
| Bayesian model choice and search strategies for mapping interacting quantitative trait Loci. | Yi N et al. | β | 2003 | β |
| Evidence of linkage of HDL level variation to APOC3 in two samples with different ascertainment. | Gagnon F et al. | β | 2003 | β |
| Fitting genetic models to twin data with binary and ordered categorical responses: a comparison of structural equation modelling and Bayesian hierarchical models. | Kuhnert PM et al. | β | 2003 | β |
| Full pedigree quantitative trait locus analysis in commercial pigs using variance components. | de Koning DJ et al. | β | 2003 | β |
| Genetic analysis workshop 13: Summary of analyses of alcohol and cigarette use phenotypes in the Framingham Heart Study. | Saccone NL et al. | β | 2003 | β |
| Information gain for genetic parameter estimation with incorporation of marker data. | Luo Y et al. | β | 2003 | β |
| Mapping viability loci using molecular markers. | Luo L et al. | β | 2003 | β |
| Multiple genome-wide analyses of smoking behavior in the Framingham Heart Study. | Goode EL et al. | β | 2003 | β |
| On different approximations to multilocus identity-by-descent calculations and the resulting power of variance component-based linkage analysis. | GΓΆring HH et al. | β | 2003 | β |
| Quantitative trait loci on chromosomes 2p, 4p, and 13q influence bone mineral density of the forearm and hip in Mexican Americans. | Kammerer CM et al. | β | 2003 | β |
| Segregation analysis of phenotypic components of learning disabilities. II. Phonological decoding. | Chapman NH et al. | β | 2003 | β |
| Summary of Group 8: Development and extension of linkage methods. | Wijsman EM | β | 2003 | β |
| Summary report: Missing data and pedigree and genotyping errors. | Badzioch MD et al. | β | 2003 | β |
| A note on estimating the posterior density of a quantitative trait locus from a Markov chain Monte Carlo sample. | Hoti FJ et al. | β | 2002 | β |
| A unified approach to joint modeling of multiple quantitative and qualitative traits in gene mapping. | Corander J et al. | β | 2002 | β |
| Candidate genes involved in cardiovascular risk factors by a family-based association study on the island of Kosrae, Federated States of Micronesia. | Han Z et al. | β | 2002 | β |
| Heritability and number of quantitative trait loci of neurocognitive functions in families with schizophrenia. | Tuulio-Henriksson A et al. | β | 2002 | β |
| Linkage analysis of quantitative trait loci in multiple line crosses. | Yi N et al. | β | 2002 | β |
| Mathematics-assisted mapping in analysis of medical disease. | SillanpÀÀ MJ | β | 2002 | β |
| Merlin--rapid analysis of dense genetic maps using sparse gene flow trees. | Abecasis GR et al. | β | 2002 | β |
| Model choice in gene mapping: what and why. | SillanpÀÀ MJ et al. | β | 2002 | β |
| Powerful regression-based quantitative-trait linkage analysis of general pedigrees. | Sham PC et al. | β | 2002 | β |
| QTL analysis in arbitrary pedigrees with incomplete marker information. | Vogl C et al. | β | 2002 | β |
| Technical note: determining peeling order using sparse matrix algorithms. | FernΓ‘ndez SA et al. | β | 2002 | β |
| Bayesian mapping of quantitative trait loci under complicated mating designs. | Yi N et al. | β | 2001 | β |
| Bayesian methods for quantitative trait loci mapping based on model selection: approximate analysis using the Bayesian information criterion. | Ball RD | β | 2001 | β |
| Bayesian oligogenic analysis of quantitative and qualitative traits in general pedigrees. | Uimari P et al. | β | 2001 | β |
| Computational issues in mapping variation affecting susceptibility to complex disorders: the chicken and the egg. | Cox NJ | β | 2001 | β |
| Efficient multipoint linkage analysis through reduction of inheritance space. | Markianos K et al. | β | 2001 | β |
| Genetic linkage methods for quantitative traits. | Amos CI et al. | β | 2001 | β |
| Genome scans for Q1 and Q2 on general population replicates using Loki. | Shmulewitz D et al. | β | 2001 | β |
| Information technology tools for efficient SNP studies. | Tolle R | β | 2001 | β |
| Introduction: bayesian models and Markov chain Monte Carlo methods. | Thomas DC | β | 2001 | β |
| Markov chain Monte Carlo linkage analysis: effect of bin width on the probability of linkage. | Slager SL et al. | β | 2001 | β |
| Markov chain Monte Carlo linkage analysis of complex quantitative phenotypes. | Hinrichs A et al. | β | 2001 | β |
| Methods for linkage analysis of quantitative trait loci in humans. | Feingold E | β | 2001 | β |
| The importance of connections: joining components of the Hutterite pedigree. | Chapman NH et al. | β | 2001 | β |
| A cholesterol-lowering gene maps to chromosome 13q. | Knoblauch H et al. | β | 2000 | β |
| A note on algorithms for genotype and allele elimination in complex pedigrees with incomplete genotype data. | Du FX et al. | β | 2000 | β |
| Bayesian mapping of quantitative trait loci for complex binary traits. | Yi N et al. | β | 2000 | β |
| Bayesian mapping of quantitative trait loci under the identity-by-descent-based variance component model. | Yi N et al. | β | 2000 | β |
| Bias in multipoint linkage analysis arising from map misspecification. | Daw EW et al. | β | 2000 | β |
| Genetic analysis of the age at menopause by using estimating equations and Bayesian random effects models. | Do KA et al. | β | 2000 | β |
| Mapping quantitative trait loci in complex pedigrees: a two-step variance component approach. | George AW et al. | β | 2000 | β |
| Mixed model analysis of quantitative trait loci. | Xu S et al. | β | 2000 | β |
| Multipoint mapping of viability and segregation distorting loci using molecular markers. | Vogl C et al. | β | 2000 | β |
| Performance of Markov chain-Monte Carlo approaches for mapping genes in oligogenic models with an unknown number of loci. | Lee JK et al. | β | 2000 | β |
| Quantitative trait loci mapping in F(2) crosses between outbred lines. | PΓ©rez-Enciso M et al. | β | 2000 | β |
| Segregation analysis of phenotypic components of learning disabilities. I. Nonword memory and digit span. | Wijsman EM et al. | β | 2000 | β |
| Statistical approaches to gene mapping. | Ott J et al. | β | 2000 | β |
| The number of trait loci in late-onset Alzheimer disease. | Daw EW et al. | β | 2000 | β |
| A Bayesian Markov chain Monte Carlo approach to map disease genes in simulated GAW11 data. | Uimari P et al. | β | 1999 | β |
| A random model approach to mapping quantitative trait loci for complex binary traits in outbred populations. | Yi N et al. | β | 1999 | β |
| Bayesian mapping of multiple quantitative trait loci from incomplete outbred offspring data. | SillanpÀÀ MJ et al. | β | 1999 | β |
| Detection of quantitative trait loci in outbred populations with incomplete marker data. | Bink MC et al. | β | 1999 | β |
| Distribution of alleles of the methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism in familial spina bifida. | Johnson WG et al. | β | 1999 | β |
| Familial analysis of event related potentials. | King TM et al. | β | 1999 | β |
| Markov chain Monte Carlo linkage analysis of a complex qualitative phenotype. | Hinrichs A et al. | β | 1999 | β |
| Monte Carlo Markov chain methods for genome screening. | Daw EW et al. | β | 1999 | β |
| Multipoint oligogenic analysis of age-at-onset data with applications to Alzheimer disease pedigrees. | Daw EW et al. | β | 1999 | β |
| Quantitative trait linkage mapping in anthropology. | Rogers J et al. | β | 1999 | β |
| Searching for alcoholism susceptibility genes using Markov chain Monte Carlo methods. | Leal SM et al. | β | 1999 | β |
| Multipoint quantitative-trait linkage analysis in general pedigrees. | Almasy L et al. | β | 1998 | β |