Age of onset of drug use and its association with DSM-IV drug abuse and dependence: results from the National Longitudinal Alcohol Epidemiologic Survey.
- Authors
- Grant, B F; Dawson, D A
- Year
- 1998
- Journal
- Journal of substance abuse
- PMID
- 9854701
- DOI
- 10.1016/s0899-3289(99)80131-x
The purpose of this study was to examine the relationship between early onset drug use and the development of lifetime DSM-IV drug abuse and dependence using a representative sample of the U.S. population. Prevalences of lifetime drug abuse and dependence were estimated for each year of age of onset of drug use from ages 13 and younger to 21 and older for the overall sample of drug users by race and gender. Linear logistic analyses were conducted to assess the relationship between age of drug use onset and lifetime drug use disorders controlling for important covariates. The major finding of this study was that early onset drug use is a significant predictor of the subsequent development of drug abuse over the life course. Early onset drug use was also a significant predictor of the subsequent development of lifetime alcohol dependence among males, females, and nonblacks, but not among blacks. After adjusting for important model covariates, the likelihood of lifetime drug abuse and dependence among the total sample of lifetime drug users was reduced by 4% and 5% with each year drug use onset was delayed. Implications of these findings are discussed in terms of the importance of collecting national data on drug use, abuse and dependence and the need for further research and its integration with prevention efforts.
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| Age-related patterns of drug use initiation among polydrug using regular psychostimulant users. | Darke S et al. | — | 2012 | → |
| Beyond primary prevention of alcohol use: a culturally specific secondary prevention program for Mexican heritage adolescents. | Marsiglia FF et al. | — | 2012 | → |
| Early attentional modulation by alcohol-related cues in young binge drinkers: an event-related potentials study. | Petit G et al. | — | 2012 | → |
| Edentulousness, denture wear and denture needs of the elderly in rural South India. | Ariga P et al. | — | 2012 | → |
| Effects of ethanol, Δ(9)-tetrahydrocannabinol, or their combination on object recognition memory and object preference in adolescent and adult male rats. | Swartzwelder NA et al. | — | 2012 | → |
| Evidence of increasing age of onset of cannabis use among younger Australians. | Lenton S et al. | — | 2012 | → |
| Externalizing behaviors are associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 gene cluster. | Stephens SH et al. | — | 2012 | → |
| Increased sensitivity to alcohol induced changes in ERK Map kinase phosphorylation and memory disruption in adolescent as compared to adult C57BL/6J mice. | Spanos M et al. | — | 2012 | → |
| Juvenile and adult rats differ in cocaine reward and expression of zif268 in the forebrain. | Hollis F et al. | — | 2012 | → |
| Orbitofrontal volumes in early adolescence predict initiation of cannabis use: a 4-year longitudinal and prospective study. | Cheetham A et al. | — | 2012 | → |
| Peer substance use as a mediator between early pubertal timing and adolescent substance use: longitudinal associations and moderating effect of maltreatment. | Negriff S et al. | — | 2012 | → |
| Personal and contextual factors in the escalation of driving after drinking across the college years. | Quinn PD et al. | — | 2012 | → |
| Social influences on morphine sensitization in adolescent rats. | Hofford RS et al. | — | 2012 | → |
| Social norm influences on evaluations of the risks associated with alcohol consumption: applying the rank-based decision by sampling model to health judgments. | Wood AM et al. | — | 2012 | → |
| Substance abuse in high school students in association with socio-demographic variables in northwest of iran. | Mohammadpoorasl A et al. | — | 2012 | → |
| Teaching the biological consequences of alcohol abuse through an online game: impacts among secondary students. | Klisch Y et al. | — | 2012 | → |
| The theory of planned behavior: precursors of marijuana use in early adolescence? | Malmberg M et al. | — | 2012 | → |
| "Unplugged": a school-based randomized control trial to prevent and reduce adolescent substance use in the Czech Republic. | Gabrhelik R et al. | — | 2012 | → |
| Use and abuse of alcohol and illicit drugs in US adolescents: results of the National Comorbidity Survey-Adolescent Supplement. | Swendsen J et al. | — | 2012 | → |
| Addiction, adolescence, and innate immune gene induction. | Crews FT et al. | — | 2011 | → |
| Adolescent C57BL/6J mice show elevated alcohol intake, but reduced taste aversion, as compared to adult mice: a potential behavioral mechanism for binge drinking. | Holstein SE et al. | — | 2011 | → |
| Age-related differences in cigarette smoking among whites and African-Americans: evidence for the crossover hypothesis. | Kandel D et al. | — | 2011 | → |
| Altered anxiety-like behavior and long-term potentiation in the bed nucleus of the stria terminalis in adult mice exposed to chronic social isolation, unpredictable stress, and ethanol beginning in adolescence. | Conrad KL et al. | — | 2011 | → |
| Binge cocaine administration in adolescent rats affects amygdalar gene expression patterns and alters anxiety-related behavior in adulthood. | Daws SE et al. | — | 2011 | → |
| Characteristics of opioid prescriptions in 2009. | Volkow ND et al. | — | 2011 | → |
| Detection of cocaine induced rat brain activation by photoacoustic tomography. | Jo J et al. | — | 2011 | → |
| Does adolescent risk taking imply weak executive function? A prospective study of relations between working memory performance, impulsivity, and risk taking in early adolescence. | Romer D et al. | — | 2011 | → |
| Early environmental factors differentially affect voluntary ethanol consumption in adolescent and adult male rats. | Daoura L et al. | — | 2011 | → |
| Exercise and substance use among American youth, 1991-2009. | Terry-McElrath YM et al. | — | 2011 | → |
| Expectancies and self-efficacy mediate the effects of impulsivity on marijuana use outcomes: an application of the acquired preparedness model. | Hayaki J et al. | — | 2011 | → |
| Hospitalizations for alcohol and drug overdoses in young adults ages 18-24 in the United States, 1999-2008: results from the Nationwide Inpatient Sample. | White AM et al. | — | 2011 | → |
| Individual vulnerability to addiction. | Swendsen J et al. | — | 2011 | → |
| Morningness/eveningness, pubertal timing, and substance use in adolescent girls. | Negriff S et al. | — | 2011 | → |
| Outcomes in women diagnosed with borderline personality disorder in adolescence. | Biskin RS et al. | — | 2011 | → |
| Parsing the Undercontrol/Disinhibition Pathway to Substance Use Disorders: A Multilevel Developmental Problem. | Zucker RA et al. | — | 2011 | → |
| Personality correlates of the common and unique variance across conduct disorder and substance misuse symptoms in adolescence. | Castellanos-Ryan N et al. | — | 2011 | → |
| Probability and predictors of transition from first use to dependence on nicotine, alcohol, cannabis, and cocaine: results of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). | Lopez-Quintero C et al. | — | 2011 | → |
| Reporting bias in the association between age at first alcohol use and heavy episodic drinking. | Sartor CE et al. | — | 2011 | → |
| Response inhibition and reward response bias mediate the predictive relationships between impulsivity and sensation seeking and common and unique variance in conduct disorder and substance misuse. | Castellanos-Ryan N et al. | — | 2011 | → |
| Substance use and exercise participation among young adults: parallel trajectories in a national cohort-sequential study. | Terry-McElrath YM et al. | — | 2011 | → |
| The association between substance use disorders and early and combined use of alcohol and marijuana in two American Indian populations. | O'Connell JM et al. | — | 2011 | → |
| The premises is the premise: understanding off- and on-premises alcohol sales outlets to improve environmental alcohol prevention strategies. | Chinman M et al. | — | 2011 | → |
| A cotwin-control analysis of drug use and abuse/dependence risk associated with early-onset cannabis use. | Grant JD et al. | — | 2010 | → |
| An animal model of social instability stress in adolescence and risk for drugs of abuse. | McCormick CM | — | 2010 | → |
| COMORBIDITY BETWEEN DEPRESSIVE AND ADDICTIVE DISORDERS IN ADOLESCENTS: ROLE OF STRESS AND HPA ACTIVITY. | Rao U | — | 2010 | → |
| Effects of alcohol use initiation patterns on high-risk behaviors among urban, low-income, young adolescents. | Komro KA et al. | — | 2010 | → |
| Genetic and environmental risk factors for adolescent-onset substance use disorders. | Meyers JL et al. | — | 2010 | → |
| Genetic, personality, and environmental predictors of drug use in adolescents. | Conner BT et al. | — | 2010 | → |
| High-risk drug use and sexual behaviors among out-of-treatment drug users: an aging and life course perspective. | Lopez WD et al. | — | 2010 | → |
| Influence of brain-derived neurotrophic factor (val66met) genetic polymorphism on the ages of onset for heroin abuse in males. | Hou H et al. | — | 2010 | → |
| Neurobiology of adolescent substance use disorders: implications for prevention and treatment. | Rutherford HJ et al. | — | 2010 | → |
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| Neurocircuitry of addiction. | Koob GF et al. | — | 2010 | → |
| Office of National Drug Control Policy: a scientist in drug policy in Washington, DC. | Madras BK | — | 2010 | → |
| Predicting drinking onset with discrete-time survival analysis in offspring from the San Diego prospective study. | Trim RS et al. | — | 2010 | → |
| Reducing underage and young adult drinking: how to address critical drinking problems during this developmental period. | Windle M et al. | — | 2010 | → |
| Sexual orientation and drug use in a longitudinal cohort study of U.S. adolescents. | Corliss HL et al. | — | 2010 | → |
| Social influences on morphine sensitization in adolescent females. | Hofford RS et al. | — | 2010 | → |
| Socially induced morphine pseudosensitization in adolescent mice. | Hodgson SR et al. | — | 2010 | → |
| The effectiveness of a school-based substance abuse prevention program: 18-month follow-up of the EU-Dap cluster randomized controlled trial. | Faggiano F et al. | — | 2010 | → |
| Trajectories of Substance Use Disorders in Youth: Identifying and Predicting Group Memberships. | Lee CY et al. | — | 2010 | → |
| Use of fake identification to purchase alcohol amongst 15-16 year olds: a cross-sectional survey examining alcohol access, consumption and harm. | Morleo M et al. | — | 2010 | → |
| Common genetic influences on the timing of first use for alcohol, cigarettes, and cannabis in young African-American women. | Sartor CE et al. | — | 2009 | → |
| Developmental epidemiology of drug use and abuse in adolescence and young adulthood: Evidence of generalized risk. | Palmer RH et al. | — | 2009 | → |
| Early-onset drug use and risk for drug dependence problems. | Chen CY et al. | — | 2009 | → |
| Executive cognitive functions and impulsivity as correlates of risk taking and problem behavior in preadolescents. | Romer D et al. | — | 2009 | → |
| Genetic and non-genetic influences on the development of co-occurring alcohol problem use and internalizing symptomatology in adolescence: a review. | Saraceno L et al. | — | 2009 | → |
| Modelling human drug abuse and addiction with dedicated small animal positron emission tomography. | Dalley JW et al. | — | 2009 | → |
| Nature and Impact of Alcohol Messages in a Youth-Oriented Television Series. | Russell CA et al. | — | 2009 | → |
| Persisting changes in basolateral amygdala mRNAs after chronic ethanol consumption. | Falco AM et al. | — | 2009 | → |
| Predictors of illicit substance dependence among individuals with alcohol dependence. | Sintov ND et al. | — | 2009 | → |
| Repeated ethanol exposure during adolescence alters the developmental trajectory of dopaminergic output from the nucleus accumbens septi. | Philpot RM et al. | — | 2009 | → |
| Socio-demographic risk factors for alcohol and drug dependence: the 10-year follow-up of the national comorbidity survey. | Swendsen J et al. | — | 2009 | → |
| Strain specific synaptic modifications on ventral tegmental area dopamine neurons after ethanol exposure. | Wanat MJ et al. | — | 2009 | → |
| Synergistic interaction between nicotine and social rewards in adolescent male rats. | Thiel KJ et al. | — | 2009 | → |
| The high prevalence of substance use disorders among recent MDMA users compared with other drug users: Implications for intervention. | Wu LT et al. | — | 2009 | → |
| Transitions from first substance use to substance use disorders in adolescence: is early onset associated with a rapid escalation? | Behrendt S et al. | — | 2009 | → |
| Acute ethanol effects on local cerebral glucose utilization in select central nervous system regions of adolescent alcohol-preferring (P) and alcohol-nonpreferring (NP) rats. | Strother WN et al. | — | 2008 | → |
| Addiction and the brain antireward system. | Koob GF et al. | — | 2008 | → |
| Adolescents with insomnia and substance abuse: consequences and comorbidities. | Shibley HL et al. | — | 2008 | → |
| Age- and sex-dependent effects of footshock stress on subsequent alcohol drinking and acoustic startle behavior in mice selectively bred for high-alcohol preference. | Chester JA et al. | — | 2008 | → |
| Age differences in the spontaneous acquisition of nicotine self-administration in male Wistar and Long-Evans rats. | Shram MJ et al. | — | 2008 | → |
| Antisocial behavioral syndromes and body mass index among adults in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions. | Goldstein RB et al. | — | 2008 | → |
| Antisocial behavioral syndromes and past-year physical health among adults in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions. | Goldstein RB et al. | — | 2008 | → |
| Cigarette smoking in the early course of bipolar disorder: association with ages-at-onset of alcohol and marijuana use. | Heffner JL et al. | — | 2008 | → |
| Comparison of ethanol locomotor sensitization in adolescent and adult DBA/2J mice. | Stevenson RA et al. | — | 2008 | → |
| Improving targets for the prevention of drug use disorders: sociodemographic predictors of transitions across drug use stages in the national comorbidity survey replication. | Swendsen J et al. | — | 2008 | → |
| Licensing teenagers: nontraffic risks and benefits in the transition to driving status. | Voas R et al. | — | 2008 | → |
| Low identification of alcohol use disorders in general practice in England. | Cheeta S et al. | — | 2008 | → |
| Nicotine and alcohol use in adolescent psychiatric inpatients: associations with diagnoses, psychosocial factors, gender and age. | Ribeiro SN et al. | — | 2008 | → |
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| Substance use disorders among inhalant users: results from the National Epidemiologic Survey on alcohol and related conditions. | Wu LT et al. | — | 2008 | → |
| Youth exposure to alcohol use and brand appearances in popular contemporary movies. | Dal Cin S et al. | — | 2008 | → |
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| Agreement between Parent and Adolescent Reports of Adolescent Substance Use. | McGillicuddy NB et al. | — | 2007 | → |
| Antisocial behavioral syndromes and DSM-IV drug use disorders in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions. | Goldstein RB et al. | — | 2007 | → |
| Does early onset of non-medical use of prescription drugs predict subsequent prescription drug abuse and dependence? Results from a national study. | McCabe SE et al. | — | 2007 | → |
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| Psychiatric disorders in inhalant users: results from The National Epidemiologic Survey on Alcohol and Related Conditions. | Wu LT et al. | — | 2007 | → |
| Substance use pathways to methamphetamine use among treated users. | Brecht ML et al. | — | 2007 | → |
| The Alcohol Dependence Syndrome, 30 years later: a commentary. the 2006 H. David Archibald lecture. | Li TK et al. | — | 2007 | → |
| The Australian Treatment Outcome Study (ATOS): what have we learnt about treatment for heroin dependence? | Darke S et al. | — | 2007 | → |
| A modified version of the Drug Abuse Screening Test among undergraduate students. | McCabe SE et al. | — | 2006 | → |
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| Genetic and environmental vulnerabilities underlying adolescent substance use and problem use: general or specific? | Young SE et al. | — | 2006 | → |
| Substance use and substance use disorders in a community sample of adolescents and young adults: incidence, age effects and patterns of use. | Perkonigg A et al. | — | 2006 | → |
| Ten years and 1 master settlement agreement later: the nature and frequency of alcohol and tobacco promotion in televised sports, 2000 through 2002. | Zwarun L | — | 2006 | → |
| Using the brain P300 response to identify novel phenotypes reflecting genetic vulnerability for adolescent substance misuse. | Yoon HH et al. | — | 2006 | → |
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| Combining research approaches to advance our understanding of drug addiction. | van den Bree MB | — | 2005 | → |
| Drug use and risk behaviours among injecting drug users: a comparison between sex workers and non-sex workers in Sydney, Australia. | Roxburgh A et al. | — | 2005 | → |
| First cannabis use: does onset shift to younger ages? Findings from 1988 to 2003 from the Dutch National School Survey on Substance Use. | Monshouwer K et al. | — | 2005 | → |
| High prevalence of substance use disorders among adolescents who use marijuana and inhalants. | Wu LT et al. | — | 2005 | → |
| Increased risk-taking decision-making but not altered response to punishment in stimulant-using young adults. | Leland DS et al. | — | 2005 | → |
| The genetics of addictions: uncovering the genes. | Goldman D et al. | — | 2005 | → |
| Adolescents' performance on the Iowa Gambling Task: implications for the development of decision making and ventromedial prefrontal cortex. | Hooper CJ et al. | — | 2004 | → |
| Inhalant abuse and dependence among adolescents in the United States. | Wu LT et al. | — | 2004 | → |
| Patterns of ecstasy use in Australia: findings from a national household survey. | Degenhardt L et al. | — | 2004 | → |
| Psychosocial processes and mechanisms of risk and protection. | — | — | 2004 | → |
| The effect of childhood conduct disorder and cognitive functioning on adolescent substance use. | Harty SC et al. | — | 2004 | → |
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| A longitudinal study of the effects of adolescent cannabis use on high school completion. | Lynskey MT et al. | — | 2003 | → |
| Escalation of drug use in early-onset cannabis users vs co-twin controls. | Lynskey MT et al. | — | 2003 | → |
| Place conditioning: age-related changes in the rewarding and aversive effects of alcohol. | Philpot RM et al. | — | 2003 | → |
| Prevalence of hepatitis C virus infection and risk factors in an incarcerated juvenile population: a pilot study. | Murray KF et al. | — | 2003 | → |
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| Office-based intervention for adolescent substance abuse. | Levy S et al. | — | 2002 | → |
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| Neurotoxicity and neurocognitive impairments with alcohol and drug-use disorders: potential roles in addiction and recovery. | Bowden SC et al. | — | 2001 | → |
| Onset and pattern of substance use in intravenous drug users of an opiate maintenance program. | Zinkernagel C et al. | — | 2001 | → |
| Origins and consequences of age at first drink. I. Associations with substance-use disorders, disinhibitory behavior and psychopathology, and P3 amplitude. | McGue M et al. | — | 2001 | → |
| Cohort trends in the age of initiation of drug use in Australia. | Degenhardt L et al. | — | 2000 | → |
| Early-onset of illicit substance use is associated with greater axis-II comorbidity, not with axis-I comorbidity. | Franken IH et al. | — | 2000 | → |
| Illicit cocaine use patterns in intravenous-naive cocaine users following investigational intravenous cocaine administration. | Kaufman MJ et al. | — | 2000 | → |
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