Development of depression: sex and the interaction between environment and a promoter polymorphism of the serotonin transporter gene.
paper
Cited
Public
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- Authors
- SjΓΆberg, Rickard L; Nilsson, Kent W; Nordquist, Niklas; Ohrvik, John; Leppert, Jerzy; LindstrΓΆm, Leif; Oreland, Lars
- Year
- 2006
- Journal
- The international journal of neuropsychopharmacology
- PMID
- 16212676
- DOI
- 10.1017/S1461145705005936
Previous research has demonstrated that a polymorphism in the serotonin transporter gene (5-HTTLPR) and adverse psychosocial circumstances interact to predict depression. The purpose of the present study was to explore the extent to which sex modulates these effects. Eighty-one boys and 119 girls (16-19 years old) were interviewed about psychosocial background variables and genotyped for the 5-HTT promoter polymorphism. There were two main results. First, boys and girls carrying the short 5-HTTLPR allele react to different kinds of environmental factors. Whereas males were affected by living in public housing rather than in own owned homes and by living with separated parents, females were affected by traumatic conflicts within the family. Second, the responses of males and females carrying the short 5-HTTLPR allele to environmental stress factors go in opposite directions. Thus, whereas females tend to develop depressive symptoms, males seem to be protected from depression. The results suggest that both the molecular and the psychosocial mechanisms underlying depression may differ between boys and girls.
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| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
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| The Relationship Between Insufficient Sleep and Depressive Symptoms in Chinese Adolescents: A National Survey of Contributing Factors. | Yan C et al. | β | 2025 | β |
| Not Just a Mood DisorderβIs Depression a Neurodevelopmental, Cognitive Disorder? Focus on Prefronto-Thalamic Circuits. | Soto NN et al. | β | 2024 | β |
| Pharmacogenetics of selective serotonin reuptake inhibitors (SSRI): A serotonin reuptake transporter (SERT)-based approach. | Sreeja V et al. | β | 2024 | β |
| Genetic Variants Associated With Resilience in Human and Animal Studies. | Cahill S et al. | β | 2022 | β |
| Screen time and adolescents' mental health before and after the COVID-19 lockdown in Switzerland: A natural experiment. | Marciano L et al. | β | 2022 | β |
| The Role of Sex in Genetic Association Studies of Depression. | Hoth KF et al. | β | 2022 | β |
| Toxoplasmosis: Targeting neurotransmitter systems in psychiatric disorders. | Nayeri T et al. | β | 2022 | β |
| Gene-environment interaction: Oxytocin receptor (OXTR) polymorphisms and parenting style as potential predictors for depressive symptoms. | Keijser R et al. | β | 2021 | β |
| Systematic review reveals multiple sexually antagonistic polymorphisms affecting human disease and complex traits. | Harper JA et al. | β | 2021 | β |
| Three-way interaction effects of early life stress, positive parenting and FKBP5 in the development of depressive symptoms in a general population. | Keijser R et al. | β | 2021 | β |
| Using an adoption design to test genetically based differences in risk for child behavior problems in response to home environmental influences. | Cree RA et al. | β | 2021 | β |
| Gender Differences in Depression: Evidence From Genetics. | Zhao L et al. | β | 2020 | β |
| Threat-Avoidance Tendencies Moderate the Link Between Serotonin Transporter Genetic Variation and Reactive Aggression. | Peeters DGA et al. | β | 2020 | β |
| Constitutive Serotonin Transporter Reduction Resembles Maternal Separation with Regard to Stress-Related Gene Expression. | Comasco E et al. | β | 2019 | β |
| <i>CACNA1C rs1006737</i>, Threatening Life Events, and Gene-Environment Interaction Predict Major Depressive Disorder. | Zhao M et al. | β | 2019 | β |
| Serotonin and aggressive behaviour in children and adolescents: a systematic review. | Runions KC et al. | β | 2019 | β |
| Understanding the Relation Between Early-Life Adversity and Depression Symptoms: The Moderating Role of Sex and an Interleukin-1Ξ² Gene Variant. | McQuaid RJ et al. | β | 2019 | β |
| Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression. | Culverhouse RC et al. | β | 2018 | β |
| Gene-environment interactions between stress and 5-HTTLPR in depression: A meta-analytic update. | Bleys D et al. | β | 2018 | β |
| Individual biological sensitivity to environmental influences: testing the differential susceptibility properties of the 5HTTLPR polymorphism in relation to depressive symptoms and delinquency in two adolescent general samples. | Γ slund C et al. | β | 2018 | β |
| Neurological and neuropsychological effects of low and moderate prenatal alcohol exposure. | Comasco E et al. | β | 2018 | β |
| Personality as an intermediate phenotype for genetic dissection of alcohol use disorder. | Oreland L et al. | β | 2018 | β |
| The serotonin transporter polymorphism (5-HTTLPR) and cortisol stress responsiveness: preliminary evidence for a modulating role for sleep quality. | van Dalfsen JH et al. | β | 2018 | β |
| Tryptophan supplementation and serotonin function: genetic variations in behavioural effects. | Gibson EL | β | 2018 | β |
| Letter to the Editor: Bias in the measurement of bias. Letter regarding 'Citation bias and selective focus on positive findings in the literature on the serotonin transporter gene (5-HTTLPR), life stress and depression'. | Vrshek-Schallhorn S et al. | β | 2017 | β |
| Organ-specific gene modulation: Principles and applications in cancer research. | Economopoulou P et al. | β | 2017 | β |
| Sex differences modulating serotonergic polymorphisms implicated in the mechanistic pathways of risk for depression and related disorders. | Perry LM et al. | β | 2017 | β |
| 5-HTTLPR and gender differences in affective disorders: A systematic review. | Gressier F et al. | β | 2016 | β |
| Depression Among People Who Inject Drugs and Their Intimate Partners in Kazakhstan. | Shaw SA et al. | β | 2016 | β |
| Depression, Stressful Life Events, and the Impact of Variation in the Serotonin Transporter: Findings from the National Longitudinal Study of Adolescent to Adult Health (Add Health). | Haberstick BC et al. | β | 2016 | β |
| Effects of Recent Stress and Variation in the Serotonin Transporter Polymorphism (5-HTTLPR) on Depressive Symptoms: A Repeated-Measures Study of Adults Age 50 and Older. | Arpawong TE et al. | β | 2016 | β |
| Financial difficulties but not other types of recent negative life events show strong interactions with 5-HTTLPR genotype in the development of depressive symptoms. | Gonda X et al. | β | 2016 | β |
| Stressful Life Events and Risk of Depression 25 Years Later: Race and Gender Differences. | Assari S et al. | β | 2016 | β |
| The Serotonin Transporter Promoter Variant, Stress, and Attentional Biases in Middle Childhood. | Kotelnikova Y et al. | β | 2016 | β |
| Depression from childhood into late adolescence: Influence of gender, development, genetic susceptibility, and peer stress. | Hankin BL et al. | β | 2015 | β |
| Family dissolution and offspring depression and depressive symptoms: A systematic review of moderation effects. | Di Manno L et al. | β | 2015 | β |
| Gender differences in association between serotonin transporter gene polymorphism and resting-state EEG activity. | Volf NV et al. | β | 2015 | β |
| Interaction of the 5-HTTLPR and childhood trauma influences memory bias in healthy individuals. | Vrijsen JN et al. | β | 2015 | β |
| Serotonin transporter availability may moderate the association between perceiving stress and depressive tendencies - A SPECT with 5-HTTLPR genotyping study. | Lin SH et al. | β | 2015 | β |
| The Involvement of Genes in Adolescent Depression: A Systematic Review. | Xia L et al. | β | 2015 | β |
| Variations in central serotonergic activity - relevance of the 5-HTTLPR, life events and their interaction. | Wielpuetz C et al. | β | 2015 | β |
| 5-HTTLPR, anxiety and gender interaction moderates right amygdala volume in healthy subjects. | Cerasa A et al. | β | 2014 | β |
| A Preliminary Examination of the Relationship Between the <i>5-HTTLPR</i> and Childhood Emotional Abuse on Depressive Symptoms in 10-12-Year-Old Youth. | Banducci AN et al. | β | 2014 | β |
| Genotypes do not confer risk for delinquency but rather alter susceptibility to positive and negative environmental factors: gene-environmentinteractions of BDNF Val66Met, 5-HTTLPR, and MAOA-uVNTR [corrected]. | Nilsson KW et al. | β | 2014 | β |
| Individual and sex differences in the consequences of victimization: Moderation by approach and avoidance motivation. | Llewellyn N et al. | β | 2014 | β |
| Interleukin 1B gene (IL1B) variation and internalizing symptoms in maltreated preschoolers. | Ridout KK et al. | β | 2014 | β |
| Poststroke depression and 5-HTTLPR. | Queirazza F et al. | β | 2014 | β |
| Serotonin transporter polymorphisms (5-HTTLPR) in emotion processing: implications from current neurobiology. | Jonassen R et al. | β | 2014 | β |
| Social subordination stress and serotonin transporter polymorphisms: associations with brain white matter tract integrity and behavior in juvenile female macaques. | Howell BR et al. | β | 2014 | β |
| The association between dopamine receptor (DRD4) gene polymorphisms and second language learning style and behavioral variability in undergraduate students in Turkey. | Maras Atabay M et al. | β | 2014 | β |
| Transcription Factor Activating Protein-2Ξ² (TFAP-2Ξ²) genotype and symptoms of attention deficit hyperactivity disorder in relation to symptoms of depression in two independent samples. | Nilsson KW et al. | β | 2014 | β |
| 5-HTTLPR X stress in adolescent depression: moderation by MAOA and gender. | Priess-Groben HA et al. | β | 2013 | β |
| Associations between serotonin transporter polymorphisms and cognitive processing applying the Emo 1-back task. | Jonassen R et al. | β | 2013 | β |
| Effect of COMT Val158Met polymorphism on personality traits and educational attainment in a longitudinal population representative study. | Lehto K et al. | β | 2013 | β |
| Gender-specific effects of brain-derived neurotrophic factor Val66Met polymorphism and childhood maltreatment on anxiety. | Min JA et al. | β | 2013 | β |
| Genotype by environment interaction and neurodevelopment III. Focus on the child's broader social ecology. | Bellani M et al. | β | 2013 | β |
| Implications of the use of genetic tests in psychiatry, with a focus on major depressive disorder: a review. | Wilde A et al. | β | 2013 | β |
| Increased anxiety in offspring reared by circadian Clock mutant mice. | Koizumi H et al. | β | 2013 | β |
| Interaction between a serotonin transporter gene promoter region polymorphism and stress predicts depressive symptoms in Chinese adolescents: a multi-wave longitudinal study. | Ming QS et al. | β | 2013 | β |
| Interactive contributions of self-regulation deficits and social motivation to psychopathology: unraveling divergent pathways to aggressive behavior and depressive symptoms. | Rudolph KD et al. | β | 2013 | β |
| Relational security moderates the effect of serotonin transporter gene polymorphism (5-HTTLPR) on stress generation and depression among adolescents. | Starr LR et al. | β | 2013 | β |
| Role of 5-HTTLPR polymorphism in the development of the inward/outward personality organization: a genetic association study. | Nardi B et al. | β | 2013 | β |
| Self-reported family socioeconomic status, the 5-HTTLPR genotype, and delinquent behavior in a community-based adolescent population. | Aslund C et al. | β | 2013 | β |
| Serotonin transporter availability in the midbrain and perceived social support in healthy volunteers. | Huang HY et al. | β | 2013 | β |
| Serotonin transporter gene moderates associations between mood, memory and hippocampal volume. | Price JS et al. | β | 2013 | β |
| The 5-HTTLPR genotype and depressiveness link: contribution of aspects of environment and gender. | Kurrikoff T et al. | β | 2013 | β |
| The psychodynamic psychotherapist's guide to the interaction among sex, genes, and environmental adversity in the etiology of depression for women. | Vigod SN et al. | β | 2013 | β |
| Three-way interaction effect of 5-HTTLPR, BDNF Val66Met, and childhood adversity on depression: a replication study. | Comasco E et al. | β | 2013 | β |
| Vulnerability to depression: a moderated mediation model of the roles of child maltreatment, peer victimization, and serotonin transporter linked polymorphic region genetic variation among children from low socioeconomic status backgrounds. | Banny AM et al. | β | 2013 | β |
| 5-HTTLPR S-allele: a genetic plasticity factor regarding the effects of life events on personality? | Kuepper Y et al. | β | 2012 | β |
| Coaction of stress and serotonin transporter genotype in predicting aggression at the transition to adulthood. | Conway CC et al. | β | 2012 | β |
| Emerging risk factors for postpartum depression: serotonin transporter genotype and omega-3 fatty acid status. | Shapiro GD et al. | β | 2012 | β |
| Future directions in vulnerability to depression among youth: integrating risk factors and processes across multiple levels of analysis. | Hankin BL | β | 2012 | β |
| How does the social environment 'get into the mind'? Epigenetics at the intersection of social and psychiatric epidemiology. | Toyokawa S et al. | β | 2012 | β |
| Interaction between serotonin transporter polymorphism (5-HTTLPR) and stressful life events in adolescents' trajectories of anxious/depressed symptoms. | Petersen IT et al. | β | 2012 | β |
| Moderation of adult depression by the serotonin transporter promoter variant (5-HTTLPR), childhood abuse and adult traumatic events in a general population sample. | Grabe HJ et al. | β | 2012 | β |
| Perception of a naturalistic stressor interacts with 5-HTTLPR/rs25531 genotype and gender to impact reward responsiveness. | Nikolova Y et al. | β | 2012 | β |
| Sex modulates the interactive effect of the serotonin transporter gene polymorphism and childhood adversity on hippocampal volume. | Everaerd D et al. | β | 2012 | β |
| Stressful life events and the serotonin transporter gene (5-HTT) in recurrent clinical depression. | Fisher HL et al. | β | 2012 | β |
| The 5-HTTLPR polymorphism moderates the effect of stressful life events on drinking behavior in college students of African descent. | Kranzler HR et al. | β | 2012 | β |
| The functional epistasis of 5-HTTLPR and BDNF Val66Met on emotion processing: a preliminary study. | Outhred T et al. | β | 2012 | β |
| The promoter of the serotonin transporter genotype, environment and depression: a hypothesis supported? | Brown GW | β | 2012 | β |
| The serotonin transporter gene and functional and pathological adaptation to environmental variation across the life span. | Homberg JR et al. | β | 2012 | β |
| The serotonin transporter gene linked polymorphic region is associated with the behavioral response to repeated stress exposure in infant rhesus macaques. | Spinelli S et al. | β | 2012 | β |
| Treatment of depressive-like behaviour in Huntington's disease mice by chronic sertraline and exercise. | Renoir T et al. | β | 2012 | β |
| A protective genetic variant for adverse environments? The role of childhood traumas and serotonin transporter gene on resilience and depressive severity in a high-risk population. | Carli V et al. | β | 2011 | β |
| Association between a serotonin transporter promoter polymorphism (5HTTLPR) and personality disorder traits in a community sample. | Blom RM et al. | β | 2011 | β |
| Building conditions, 5-HTTLPR genotype, and depressive symptoms in adolescent males and females. | Uddin M et al. | β | 2011 | β |
| Childhood abuse and migraine: epidemiology, sex differences, and potential mechanisms. | Tietjen GE et al. | β | 2011 | β |
| Chronic family stress interacts with 5-HTTLPR to predict prospective depressive symptoms among youth. | Jenness JL et al. | β | 2011 | β |
| Effects of the serotonin transporter (5-HTTLPR) and Ξ±2A-adrenoceptor (C-1291G) genotypes on substance use in children and adolescents: a longitudinal study. | MerenΓ€kk L et al. | β | 2011 | β |
| Forensic neurosciences: from basic research to applications and pitfalls. | Sartori G et al. | β | 2011 | β |
| Gene-environment interactions: early life stress and risk for depressive and anxiety disorders. | Nugent NR et al. | β | 2011 | β |
| Influence of the interaction between the serotonin 1A receptor C-1019G polymorphism and negative life stressors on the development of depression. | Kim HK et al. | β | 2011 | β |
| Life stressors and 5-HTTLPR interaction in relation to midpregnancy depressive symptoms among African-American women. | Scheid JM et al. | β | 2011 | β |
| Parental depressive feelings, parental support, and the serotonin transporter gene as predictors of adolescent depressive feelings: a latent growth curve analysis. | van Roekel E et al. | β | 2011 | β |
| Prenatal Cocaine Disrupts Serotonin Signaling-Dependent Behaviors: Implications for Sex Differences, Early Stress and Prenatal SSRI Exposure. | Williams SK et al. | β | 2011 | β |
| Research review: gene-environment interaction research in youth depression - a systematic review with recommendations for future research. | Dunn EC et al. | β | 2011 | β |
| Sensitivity to the depressogenic effect of stress and HPA-axis reactivity in adolescence: a review of gender differences. | Oldehinkel AJ et al. | β | 2011 | β |
| Serotonin transporter gene variants and prediction of stress-induced risk for psychological distress. | Stefanis NC et al. | β | 2011 | β |
| Sexually dimorphic serotonergic dysfunction in a mouse model of Huntington's disease and depression. | Renoir T et al. | β | 2011 | β |
| The possible contributory role of the S allele of 5-HTTLPR in the emergence of suicidality. | Gonda X et al. | β | 2011 | β |
| The psychological neuroscience of depression: implications for understanding effects of deep brain stimulation. | SjΓΆberg RL et al. | β | 2011 | β |
| The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation. | Karg K et al. | β | 2011 | β |
| War exposure, 5-HTTLPR genotype and lifetime risk of depression. | Artero S et al. | β | 2011 | β |
| A prospective cohort study investigating factors associated with depression during medical internship. | Sen S et al. | β | 2010 | β |
| Arguable assumptions, debatable conclusions. | Kaufman J et al. | β | 2010 | β |
| Association between a serotonin transporter gene variant and hopelessness among men in the Heart and Soul Study. | Kangelaris KN et al. | β | 2010 | β |
| Chronic and acute stress, gender, and serotonin transporter gene-environment interactions predicting depression symptoms in youth. | Hammen C et al. | β | 2010 | β |
| Current developments and controversies: does the serotonin transporter gene-linked polymorphic region (5-HTTLPR) modulate the association between stress and depression? | Wankerl M et al. | β | 2010 | β |
| Gender differences in the genetic and environmental determinants of adolescent depression. | Uddin M et al. | β | 2010 | β |
| Gene-environment interactions and response to social intrusion in male and female rhesus macaques. | Schwandt ML et al. | β | 2010 | β |
| Incorporating the social environment in genotype environment interaction studies of mental disorders. | Koenen KC et al. | β | 2010 | β |
| Interaction of chronic stress with serotonin transporter and catechol-O-methyltransferase polymorphisms in predicting youth depression. | Conway CC et al. | β | 2010 | β |
| Loneliness in adolescence: gene x environment interactions involving the serotonin transporter gene. | van Roekel E et al. | β | 2010 | β |
| Meta-analysis of the BDNF Val66Met polymorphism in major depressive disorder: effects of gender and ethnicity. | Verhagen M et al. | β | 2010 | β |
| Serotonin, genetic variability, behaviour, and psychiatric disorders--a review. | Nordquist N et al. | β | 2010 | β |
| Serotonin-transporter-linked promoter region polymorphism and serotonin transporter binding in drug-naΓ―ve patients with major depression. | Joensuu M et al. | β | 2010 | β |
| The serotonin transporter polymorphism (5-HTTLPR): allelic variation and links with depressive symptoms. | Goldman N et al. | β | 2010 | β |
| 5-HTTLPR modulates antidepressant efficacy in depressed women. | Gressier F et al. | β | 2009 | β |
| Aggression and 5HTT polymorphism in females: study of synchronized swimming and control groups. | Sysoeva OV et al. | β | 2009 | β |
| Children's autobiographical reports about sexual abuse: A narrative review of the research literature. | SjΓΆberg RL et al. | β | 2009 | β |
| Clinical implications of genetic variation in the serotonin transporter promoter region: a review. | Luddington NS et al. | β | 2009 | β |
| Development of sex differences in depressive and co-occurring anxious symptoms during adolescence: descriptive trajectories and potential explanations in a multiwave prospective study. | Hankin BL | β | 2009 | β |
| Emergent research in the cause of mental illness in women across the lifespan. | Vigod SN et al. | β | 2009 | β |
| Gender moderates the relationship between mania spectrum and serotonin transporter polymorphisms in depression. | Rucci P et al. | β | 2009 | β |
| Gene X environment interactions at the serotonin transporter locus. | MunafΓ² MR et al. | β | 2009 | β |
| HPA-axis regulation at in-patient admission is associated with antidepressant therapy outcome in male but not in female depressed patients. | Binder EB et al. | β | 2009 | β |
| Impact of the interaction between the 5HTTLPR polymorphism and maltreatment on adolescent depression. A population-based study. | Aslund C et al. | β | 2009 | β |
| Interaction between genetic polymorphisms and stressful life events in first episode depression. | Bukh JD et al. | β | 2009 | β |
| Interaction between the 5-HTTLPR serotonin transporter polymorphism and environmental adversity for mood and anxiety psychopathology: evidence from a high-risk community sample of young adults. | Laucht M et al. | β | 2009 | β |
| Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. | Risch N et al. | β | 2009 | β |
| Issues concerning feedback about genetic testing and risk of depression. | Wilhelm K et al. | β | 2009 | β |
| Moderation of antidepressant response by the serotonin transporter gene. | Huezo-Diaz P et al. | β | 2009 | β |
| Molecular epidemiology of major depressive disorder. | Kiyohara C et al. | β | 2009 | β |
| Multifinality in the development of personality disorders: a Biology x Sex x Environment interaction model of antisocial and borderline traits. | Beauchaine TP et al. | β | 2009 | β |
| Personality and the serotonin transporter gene: Associations in a longitudinal population-based study. | Harro J et al. | β | 2009 | β |
| Prevention effects moderate the association of 5-HTTLPR and youth risk behavior initiation: gene x environment hypotheses tested via a randomized prevention design. | Brody GH et al. | β | 2009 | β |
| Sex influences the effect of a lifelong increase in serotonin transporter function on cerebral metabolism. | Dawson N et al. | β | 2009 | β |
| Smoking as a product of gene-environment interaction. | Nilsson KW et al. | β | 2009 | β |
| The norepinephrine transporter gene modulates the relationship between urban/rural residency and major depressive disorder in a Chinese population. | Xu Y et al. | β | 2009 | β |
| The roles of sex and serotonin transporter levels in age- and stress-related emotionality in mice. | Joeyen-Waldorf J et al. | β | 2009 | β |
| Transcription factor AP-2 beta genotype and psychosocial adversity in relation to adolescent depressive symptomatology. | Nilsson KW et al. | β | 2009 | β |
| Two repeated maternal separation procedures differentially affect brain 5-hydroxytryptamine transporter and receptors in young and adult male and female rats. | Oreland S et al. | β | 2009 | β |
| 5-HTTLPR and gender moderate changes in negative affect responses to tryptophan infusion. | Brummett BH et al. | β | 2008 | β |
| A functional serotonin transporter promoter gene polymorphism increases ADHD symptoms in delinquents: interaction with adverse childhood environment. | Retz W et al. | β | 2008 | β |
| A multilevel analysis of the influence of Apolipoprotein E genotypes on depressive symptoms in late-life moderated by the environment. | Yen YC et al. | β | 2008 | β |
| Associations among central nervous system serotonergic function and neuroticism are moderated by gender. | Brummett BH et al. | β | 2008 | β |
| Associations between an alpha 2A adrenergic receptor gene polymorphism and adolescent personality. | MΓ€estu J et al. | β | 2008 | β |
| Depression and the serotonin transporter 5-HTTLPR polymorphism: a review and a hypothesis concerning gene-environment interaction. | Brown GW et al. | β | 2008 | β |
| Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphic region (5-HTTLPR). | Brummett BH et al. | β | 2008 | β |
| Effects of long-term stress and recovery on the prefrontal cortex and dentate gyrus in male and female rats. | Lin Y et al. | β | 2008 | β |
| Females do not express learned helplessness like males do. | Dalla C et al. | β | 2008 | β |
| Gene-environment interactions in depression research: genetic polymorphisms and life-stress polyprocedures. | Monroe SM et al. | β | 2008 | β |
| Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene. | Bradley RG et al. | β | 2008 | β |
| Meta-analysis of the cognitive effects of the catechol-O-methyltransferase gene Val158/108Met polymorphism. | Barnett JH et al. | β | 2008 | β |
| New evidence for the association of the serotonin transporter gene (SLC6A4) haplotypes, threatening life events, and depressive phenotype. | Lazary J et al. | β | 2008 | β |
| Serotonergic function, two-mode models of self-regulation, and vulnerability to depression: what depression has in common with impulsive aggression. | Carver CS et al. | β | 2008 | β |
| Serotonin transporter (5-HTTLPR) and monoamine oxidase (MAOA) promoter polymorphisms in women with severe alcoholism. | Gokturk C et al. | β | 2008 | β |
| The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis. | Uher R et al. | β | 2008 | β |
| The modulatory influence of polymorphism of the serotonin transporter gene on characteristics of mental maladaptation in relatives of patients with endogenous psychoses. | Alfimova MV et al. | β | 2008 | β |
| Adolescent girls and criminal activity: role of MAOA-LPR genotype and psychosocial factors. | SjΓΆberg RL et al. | β | 2007 | β |
| Genes encoding for AP-2beta and the Serotonin Transporter are associated with the Personality Character Spiritual Acceptance. | Nilsson KW et al. | β | 2007 | β |
| Interactive effects of sex and 5-HTTLPR on mood and impulsivity during tryptophan depletion in healthy people. | Walderhaug E et al. | β | 2007 | β |
| Molecular genetics of bipolar disorder and depression. | Kato T | β | 2007 | β |
| Monoamine oxidases: activities, genotypes and the shaping of behaviour. | Oreland L et al. | β | 2007 | β |
| Serotonin transporter polymorphism, memory and hippocampal volume in the elderly: association and interaction with cortisol. | O'Hara R et al. | β | 2007 | β |
| Shaming experiences and the association between adolescent depression and psychosocial risk factors. | Aslund C et al. | β | 2007 | β |
| The risk for depression conferred by stressful life events is modified by variation at the serotonin transporter 5HTTLPR genotype: evidence from the Spanish PREDICT-Gene cohort. | Cervilla JA et al. | β | 2007 | β |