A high-resolution recombination map of the human genome.
paper
Cited
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- Authors
- Kong, Augustine; Gudbjartsson, Daniel F; Sainz, Jesus; Jonsdottir, Gudrun M; Gudjonsson, Sigurjon A; Richardsson, Bjorgvin; Sigurdardottir, Sigrun; Barnard, John; Hallbeck, Bjorn; Masson, Gisli; Shlien, Adam; Palsson, Stefan T; Frigge, Michael L; Thorgeirsson, Thorgeir E; Gulcher, Jeffrey R; Stefansson, Kari
- Year
- 2002
- Journal
- Nature genetics
- PMID
- 12053178
- DOI
- 10.1038/ng917
Determination of recombination rates across the human genome has been constrained by the limited resolution and accuracy of existing genetic maps and the draft genome sequence. We have genotyped 5,136 microsatellite markers for 146 families, with a total of 1,257 meiotic events, to build a high-resolution genetic map meant to: (i) improve the genetic order of polymorphic markers; (ii) improve the precision of estimates of genetic distances; (iii) correct portions of the sequence assembly and SNP map of the human genome; and (iv) build a map of recombination rates. Recombination rates are significantly correlated with both cytogenetic structures (staining intensity of G bands) and sequence (GC content, CpG motifs and poly(A)/poly(T) stretches). Maternal and paternal chromosomes show many differences in locations of recombination maxima. We detected systematic differences in recombination rates between mothers and between gametes from the same mother, suggesting that there is some underlying component determined by both genetic and environmental factors that affects maternal recombination rates.
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| Purifying selection shapes the coincident SNP distribution of primate coding sequences. | Chen CY et al. | β | 2016 | β |
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| A Scale-Corrected Comparison of Linkage Disequilibrium Levels between Genic and Non-Genic Regions. | Berger S et al. | β | 2015 | β |
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| Fine mapping analysis confirms and strengthens linkage of four chromosomal regions in familial hypospadias. | SΓΆderhΓ€ll C et al. | β | 2015 | β |
| Genetic influences on response to novel objects and dimensions of personality in Papio baboons. | Johnson Z et al. | β | 2015 | β |
| Genome-wide amplification of proviral sequences reveals new polymorphic HERV-K(HML-2) proviruses in humans and chimpanzees that are absent from genome assemblies. | Macfarlane CM et al. | β | 2015 | β |
| Genome-wide maps of recombination and chromosome segregation in human oocytes and embryos show selection for maternal recombination rates. | Ottolini CS et al. | β | 2015 | β |
| Genome-wide patterns and properties of de novo mutations in humans. | Francioli LC et al. | β | 2015 | β |
| Homozygous missense mutation in STYXL1 associated with moderate intellectual disability, epilepsy and behavioural complexities. | Isrie M et al. | β | 2015 | β |
| Identification and characterization of the highly polymorphic locus D14S739 in the Han Chinese population. | Shao C et al. | β | 2015 | β |
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| MFN2 deletion of exons 7 and 8: founder mutation in the UK population. | Carr AS et al. | β | 2015 | β |
| Microsatellite-centromere mapping in common carp through half-tetrad analysis in diploid meiogynogenetic families. | Feng X et al. | β | 2015 | β |
| MuSK: a new target for lethal fetal akinesia deformation sequence (FADS). | Wilbe M et al. | β | 2015 | β |
| On the Recombination Rate Estimation in the Presence of Population Substructure. | Hecker J et al. | β | 2015 | β |
| Resolving the complexity of the human genome using single-molecule sequencing. | Chaisson MJ et al. | β | 2015 | β |
| Soft shoulders ahead: spurious signatures of soft and partial selective sweeps result from linked hard sweeps. | Schrider DR et al. | β | 2015 | β |
| Strong artificial selection in domestic mammals did not result in an increased recombination rate. | MuΓ±oz-Fuentes V et al. | β | 2015 | β |
| Strong Selective Sweeps on the X Chromosome in the Human-Chimpanzee Ancestor Explain Its Low Divergence. | Dutheil JY et al. | β | 2015 | β |
| The Impact of Recombination Hotspots on Genome Evolution of a Fungal Plant Pathogen. | Croll D et al. | β | 2015 | β |
| The molecular biology of meiosis in plants. | Mercier R et al. | β | 2015 | β |
| The Nature of Genetic Variation for Complex Traits Revealed by GWAS and Regional Heritability Mapping Analyses. | Caballero A et al. | β | 2015 | β |
| Variation of Meiotic Recombination Rates and MLH1 Foci Distribution in Spermatocytes of Cattle, Sheep and Goats. | FrΓΆhlich J et al. | β | 2015 | β |
| A 1,100-year-old founder effect mutation in IL12B gene is responsible for Mendelian susceptibility to mycobacterial disease in Tunisian patients. | Ben-Mustapha I et al. | β | 2014 | β |
| A fine-scale recombination map of the human-chimpanzee ancestor reveals faster change in humans than in chimpanzees and a strong impact of GC-biased gene conversion. | Munch K et al. | β | 2014 | β |
| A general approach for haplotype phasing across the full spectrum of relatedness. | O'Connell J et al. | β | 2014 | β |
| A genome-wide map of adeno-associated virus-mediated human gene targeting. | Deyle DR et al. | β | 2014 | β |
| An examination of the relationship between hotspots and recombination associated with chromosome 21 nondisjunction. | Oliver TR et al. | β | 2014 | β |
| Approaches for the identification of genetic modifiers of nutrient dependent phenotypes: examples from folate. | Zinck JW et al. | β | 2014 | β |
| Autosomal dominant partial epilepsy with auditory features: a new locus on chromosome 19q13.11-q13.31. | Bisulli F et al. | β | 2014 | β |
| Bayesian inference of shared recombination hotspots between humans and chimpanzees. | Wang Y et al. | β | 2014 | β |
| Common and low-frequency variants associated with genome-wide recombination rate. | Kong A et al. | β | 2014 | β |
| Contrasting X-linked and autosomal diversity across 14 human populations. | Arbiza L et al. | β | 2014 | β |
| Crossing-over in a hypervariable species preferentially occurs in regions of high local similarity. | Seplyarskiy VB et al. | β | 2014 | β |
| Demography and the age of rare variants. | Mathieson I et al. | β | 2014 | β |
| DNA recombination. Recombination initiation maps of individual human genomes. | Pratto F et al. | β | 2014 | β |
| Evidence for dysregulation of genome-wide recombination in oocytes with nondisjoined chromosomes 21. | Middlebrooks CD et al. | β | 2014 | β |
| Evidence for evolutionary and nonevolutionary forces shaping the distribution of human genetic variants near transcription start sites. | Scala G et al. | β | 2014 | β |
| Evolutionary analysis identifies an MX2 haplotype associated with natural resistance to HIV-1 infection. | Sironi M et al. | β | 2014 | β |
| Examining variation in recombination levels in the human female: a test of the production-line hypothesis. | Rowsey R et al. | β | 2014 | β |
| Genome-wide association study yields variants at 20p12.2 that associate with urinary bladder cancer. | Rafnar T et al. | β | 2014 | β |
| Genome-wide inference of ancestral recombination graphs. | Rasmussen MD et al. | β | 2014 | β |
| High-resolution linkage map for two honeybee chromosomes: the hotspot quest. | Mougel F et al. | β | 2014 | β |
| High-resolution sex-specific linkage maps of the mouse reveal polarized distribution of crossovers in male germline. | Liu EY et al. | β | 2014 | β |
| Interplay of interlocus gene conversion and crossover in segmental duplications under a neutral scenario. | HartasΓ‘nchez DA et al. | β | 2014 | β |
| Inverted segment size and the presence of recombination hot spot clusters matter in sperm segregation analysis. | Bhatt SS et al. | β | 2014 | β |
| Joint analysis of sequence data and single-nucleotide polymorphism data using pedigree information for imputation and recombination inference. | Song S et al. | β | 2014 | β |
| Joint assembly and genetic mapping of the Atlantic horseshoe crab genome reveals ancient whole genome duplication. | Nossa CW et al. | β | 2014 | β |
| Meiotic recombination analyses of individual chromosomes in male domestic pigs (Sus scrofa domestica). | Mary N et al. | β | 2014 | β |
| Nonhuman genetics. Strong male bias drives germline mutation in chimpanzees. | Venn O et al. | β | 2014 | β |
| Novel risk loci for rheumatoid arthritis in Han Chinese and congruence with risk variants in Europeans. | Jiang L et al. | β | 2014 | β |
| Population genomic analysis reveals no evidence for GC-biased gene conversion in Drosophila melanogaster. | Robinson MC et al. | β | 2014 | β |
| Quantitative linkage for autism spectrum disorders symptoms in attention-deficit/hyperactivity disorder: significant locus on chromosome 7q11. | Nijmeijer JS et al. | β | 2014 | β |
| Recombination in the human Pseudoautosomal region PAR1. | Hinch AG et al. | β | 2014 | β |
| Recombination locations and rates in beef cattle assessed from parent-offspring pairs. | Weng ZQ et al. | β | 2014 | β |
| The genomic architecture of population divergence between subspecies of the European rabbit. | Carneiro M et al. | β | 2014 | β |
| The impact of accelerating faster than exponential population growth on genetic variation. | Reppell M et al. | β | 2014 | β |
| The role of mutation rate variation and genetic diversity in the architecture of human disease. | Eyre-Walker YC et al. | β | 2014 | β |
| Unraveling recombination rate evolution using ancestral recombination maps. | Munch K et al. | β | 2014 | β |
| Weak negative and positive selection and the drift load at splice sites. | Denisov SV et al. | β | 2014 | β |
| A comprehensive search for recombinogenic motifs in the human genome. | Johnston HR et al. | β | 2013 | β |
| A genome scan conducted in a multigenerational pedigree with convergent strabismus supports a complex genetic determinism. | Georges A et al. | β | 2013 | β |
| A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1). | Rubicz R et al. | β | 2013 | β |
| Analysis of 8 X-chromosomal markers in the population of central Croatia. | GrΕ‘koviΔ B et al. | β | 2013 | β |
| A scalable and flexible approach for investigating the genomic landscapes of phylogenetic incongruence. | Prasad AB et al. | β | 2013 | β |
| A single-nucleotide polymorphism of human neuropeptide s gene originated from Europe shows decreased bioactivity. | Deng C et al. | β | 2013 | β |
| Cytological studies of human meiosis: sex-specific differences in recombination originate at, or prior to, establishment of double-strand breaks. | Gruhn JR et al. | β | 2013 | β |
| Distribution of recombination hotspots in the human genome--a comparison of computer simulations with real data. | Mackiewicz D et al. | β | 2013 | β |
| DNA replication timing and higher-order nuclear organization determine single-nucleotide substitution patterns in cancer genomes. | Liu L et al. | β | 2013 | β |
| Enhanced maternal origin of the 22q11.2 deletion in velocardiofacial and DiGeorge syndromes. | Delio M et al. | β | 2013 | β |
| Evidence of recent natural selection on the Southeast Asian deletion (--(SEA)) causing Ξ±-thalassemia in South China. | Qiu QW et al. | β | 2013 | β |
| Fine-scale mapping of meiotic recombination in Asians. | Bleazard T et al. | β | 2013 | β |
| Genetic susceptibility to non-necrotizing erysipelas/cellulitis. | Hannula-Jouppi K et al. | β | 2013 | β |
| Genome-wide association study of schizophrenia using microsatellite markers in the Japanese population. | Shibata H et al. | β | 2013 | β |
| Genome-wide linkage analyses of 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. | Greenwood TA et al. | β | 2013 | β |
| Genome-wide linkage analysis of carotid artery lumen diameter: the strong heart family study. | Bella JN et al. | β | 2013 | β |
| Haplotype analysis and ancient origin of the BRCA1 c.4035delA Baltic founder mutation. | JanaviΔius R et al. | β | 2013 | β |
| Haplotype analysis of the 185delAG BRCA1 mutation in ethnically diverse populations. | Laitman Y et al. | β | 2013 | β |
| Haplotype co-segregation with attention deficit-hyperactivity disorder in unrelated German multi-generation families. | Lin MK et al. | β | 2013 | β |
| Heritability and genome-wide SNP linkage analysis of temperament in bipolar disorder. | Greenwood TA et al. | β | 2013 | β |
| Heritability and linkage analysis of personality in bipolar disorder. | Greenwood TA et al. | β | 2013 | β |
| Homeodomain-interacting protein kinase2 in human idiopathic pulmonary fibrosis. | Ricci A et al. | β | 2013 | β |
| How hot are drosophila hotspots? examining recombination rate variation and associations with nucleotide diversity, divergence, and maternal age in Drosophila pseudoobscura. | Manzano-Winkler B et al. | β | 2013 | β |
| Identification of a PKP2 gene deletion in a family with arrhythmogenic right ventricular cardiomyopathy. | Li Mura IE et al. | β | 2013 | β |
| Identification of pleiotropic genetic effects on obesity and brain anatomy. | Curran JE et al. | β | 2013 | β |
| Inferring demographic history from a spectrum of shared haplotype lengths. | Harris K et al. | β | 2013 | β |
| Initiation of meiotic recombination: how and where? Conservation and specificities among eukaryotes. | de Massy B | β | 2013 | β |
| Large C9orf72 hexanucleotide repeat expansions are seen in multiple neurodegenerative syndromes and are more frequent than expected in the UK population. | Beck J et al. | β | 2013 | β |
| Microsatellites as targets of natural selection. | Haasl RJ et al. | β | 2013 | β |
| Next-generation sequencing of paired tyrosine kinase inhibitor-sensitive and -resistant EGFR mutant lung cancer cell lines identifies spectrum of DNA changes associated with drug resistance. | Jia P et al. | β | 2013 | β |
| 'North Sea' progressive myoclonus epilepsy: phenotype of subjects with GOSR2 mutation. | BoissΓ© Lomax L et al. | β | 2013 | β |
| Phylogenetic patterns of GC-biased gene conversion in placental mammals and the evolutionary dynamics of recombination landscapes. | Lartillot N | β | 2013 | β |
| Population Genomics of Human Adaptation. | Lachance J et al. | β | 2013 | β |
| Population-scale analysis of human microsatellites reveals novel sources of exonic variation. | McIver LJ et al. | β | 2013 | β |
| QTL mapping of leukocyte telomere length in American Indians: the Strong Heart Family Study. | Zhu Y et al. | β | 2013 | β |
| Recombination rates and genomic shuffling in human and chimpanzee--a new twist in the chromosomal speciation theory. | FarrΓ© M et al. | β | 2013 | β |
| Reconstructing past changes in locus-specific recombination rates. | Cox MP et al. | β | 2013 | β |
| Segmenting the human genome based on states of neutral genetic divergence. | Kuruppumullage Don P et al. | β | 2013 | β |
| Short indels are subject to insertion-biased gene conversion. | Leushkin EV et al. | β | 2013 | β |
| Statistical genetic analysis of serological measures of common, chronic infections in Alaska Native participants in the GOCADAN study. | Rubicz R et al. | β | 2013 | β |
| The evolution of lineage-specific clusters of single nucleotide substitutions in the human genome. | Xu K et al. | β | 2013 | β |
| The influence of genomic context on mutation patterns in the human genome inferred from rare variants. | Schaibley VM et al. | β | 2013 | β |
| Using population admixture to help complete maps of the human genome. | Genovese G et al. | β | 2013 | β |
| A direct characterization of human mutation based on microsatellites. | Sun JX et al. | β | 2012 | β |
| A high density recombination map of the pig reveals a correlation between sex-specific recombination and GC content. | Tortereau F et al. | β | 2012 | β |
| A high-resolution 15,000(Rad) radiation hybrid panel for the domestic cat. | Bach LH et al. | β | 2012 | β |
| A microsatellite linkage map of striped bass (Morone saxatilis) reveals conserved synteny with the three-spined stickleback (Gasterosteus aculeatus). | Liu S et al. | β | 2012 | β |
| Analysis of Xq27-28 linkage in the international consortium for prostate cancer genetics (ICPCG) families. | Bailey-Wilson JE et al. | β | 2012 | β |
| An international collaborative family-based whole genome quantitative trait linkage scan for myopic refractive error. | Abbott D et al. | β | 2012 | β |
| A tale of two haplotypes: the EDA2R/AR Intergenic region is the most divergent genomic segment between Africans and East Asians in the human genome. | Casto AM et al. | β | 2012 | β |
| A two-stage matched case-control study on multiple hypertensive candidate genes in Han Chinese. | Kuo TY et al. | β | 2012 | β |
| A unified framework for haplotype inference in nuclear families. | Iliadis A et al. | β | 2012 | β |
| Autosomal dominant late-onset spinal motor neuronopathy is linked to a new locus on chromosome 22q11.2-q13.2. | PenttilΓ€ S et al. | β | 2012 | β |
| A variable age of onset segregation model for linkage analysis, with correction for ascertainment, applied to glioma. | Sun X et al. | β | 2012 | β |
| A Whole-Chromosome Analysis of Meiotic Recombination in Drosophila melanogaster. | Miller DE et al. | β | 2012 | β |
| Chromatin organization is a major influence on regional mutation rates in human cancer cells. | Schuster-BΓΆckler B et al. | β | 2012 | β |
| Collaborative genetic mapping of 12 forensic short tandem repeat (STR) loci on the human X chromosome. | Nothnagel M et al. | β | 2012 | β |
| Complex relationship between meiotic recombination frequency and autosomal synaptonemal complex length per cell in normal human males. | Pan Z et al. | β | 2012 | β |
| Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome. | Axelsson E et al. | β | 2012 | β |
| Designs combining instrumental variables with case-control: estimating principal strata causal effects. | Shinohara RT et al. | β | 2012 | β |
| Detection of DNA hybridization on chemically modified graphene platforms. | Giovanni M et al. | β | 2012 | β |
| Estimating recombination rates from genetic variation in humans. | Auton A et al. | β | 2012 | β |
| Fine scale analysis of crossover and non-crossover and detection of recombination sequence motifs in the honeybee (Apis mellifera). | Bessoltane N et al. | β | 2012 | β |
| FTEC: a coalescent simulator for modeling faster than exponential growth. | Reppell M et al. | β | 2012 | β |
| Generation of a multi-locus chicken introgression line to study the effects of genetic interactions on metabolic phenotypes in chickens. | Ek W et al. | β | 2012 | β |
| Genetic variants in REC8, RNF212, and PRDM9 influence male recombination in cattle. | Sandor C et al. | β | 2012 | β |
| Genome-wide linkage scan for quantitative trait loci underlying normal variation in heel bone ultrasound measures. | Lee M et al. | β | 2012 | β |
| Genomic consequences of genetic rescue in an insular population of bighorn sheep (Ovis canadensis). | Miller JM et al. | β | 2012 | β |
| Guanosine triphosphate cyclohydrolase 1 promoter deletion causes dopa-responsive dystonia. | Theuns J et al. | β | 2012 | β |
| Haplotype inference. | Delaneau O et al. | β | 2012 | β |
| HELLP babies link a novel lincRNA to the trophoblast cell cycle. | van Dijk M et al. | β | 2012 | β |
| High dimensional endophenotype ranking in the search for major depression risk genes. | Glahn DC et al. | β | 2012 | β |
| Improved multiplex ligation-dependent probe amplification analysis identifies a deleterious PMS2 allele generated by recombination with crossover between PMS2 and PMS2CL. | Wernstedt A et al. | β | 2012 | β |
| Inferring the history of population size change from genome-wide SNP data. | Theunert C et al. | β | 2012 | β |
| Interplay between modifications of chromatin and meiotic recombination hotspots. | Brachet E et al. | β | 2012 | β |
| Inversion and crossover recombination contributions to the spacing between two functionally linked genes. | Clark BK et al. | β | 2012 | β |
| Localized DNA cleavage secondary to genotoxic exposure adjacent to an Alu inverted repeat. | Ho B et al. | β | 2012 | β |
| Long-range autocorrelations of CpG islands in the human genome. | Koester B et al. | β | 2012 | β |
| Maternal transmission effect of a PDGF-C SNP on nonsyndromic cleft lip with or without palate from a Chinese population. | Wu D et al. | β | 2012 | β |
| Meiotic recombinations within major histocompatibility complex of human embryos. | Taylan F et al. | β | 2012 | β |
| Population identification using genetic data. | Lawson DJ et al. | β | 2012 | β |
| Probing meiotic recombination and aneuploidy of single sperm cells by whole-genome sequencing. | Lu S et al. | β | 2012 | β |
| Recombination drives vertebrate genome contraction. | Nam K et al. | β | 2012 | β |
| Recombination mapping using Boolean logic and high-density SNP genotyping for exome sequence filtering. | Markello TC et al. | β | 2012 | β |
| Recombination rates across porcine autosomes inferred from high-density linkage maps. | MuΓ±oz M et al. | β | 2012 | β |
| Recombination rate variation and speciation: theoretical predictions and empirical results from rabbits and mice. | Nachman MW et al. | β | 2012 | β |
| Scrambling eggs: meiotic drive and the evolution of female recombination rates. | Brandvain Y et al. | β | 2012 | β |
| Systems genetics of the nuclear factor-ΞΊB signal transduction network. I. Detection of several quantitative trait loci potentially relevant to aging. | Diego VP et al. | β | 2012 | β |
| TGFB2 mutations cause familial thoracic aortic aneurysms and dissections associated with mild systemic features of Marfan syndrome. | Boileau C et al. | β | 2012 | β |
| The architecture of long-range haplotypes shared within and across populations. | Gusev A et al. | β | 2012 | β |
| The effect of deleterious mutations and age on recombination in Drosophila melanogaster. | Tedman-Aucoin K et al. | β | 2012 | β |
| The expression of preaxial polydactyly is influenced by modifying genetic elements and is not maintained by chromosomal inversion in an avian biomedical model. | Robb EA et al. | β | 2012 | β |
| The large-scale distribution of somatic mutations in cancer genomes. | Hodgkinson A et al. | β | 2012 | β |
| The role of GC-biased gene conversion in shaping the fastest evolving regions of the human genome. | Kostka D et al. | β | 2012 | β |
| The sex-specific impact of meiotic recombination on nucleotide composition. | Popa A et al. | β | 2012 | β |
| Utility of SNP arrays in detecting, quantifying, and determining meiotic origin of tetrasomy 12p in blood from individuals with Pallister-Killian syndrome. | Conlin LK et al. | β | 2012 | β |
| Variants in CPT1A, FADS1, and FADS2 are Associated with Higher Levels of Estimated Plasma and Erythrocyte Delta-5 Desaturases in Alaskan Eskimos. | Voruganti VS et al. | β | 2012 | β |
| Zinc finger binding motifs do not explain recombination rate variation within or between species of Drosophila. | Heil CS et al. | β | 2012 | β |
| 4-aminobutyrate aminotransferase (ABAT): genetic and pharmacological evidence for an involvement in gastro esophageal reflux disease. | Jirholt J et al. | β | 2011 | β |
| A 3p26-3p25 genetic linkage finding for DSM-IV major depression in heavy smoking families. | Pergadia ML et al. | β | 2011 | β |
| Adaptive selection of an incretin gene in Eurasian populations. | Chang CL et al. | β | 2011 | β |
| Age-dependent recombination rates in human pedigrees. | Hussin J et al. | β | 2011 | β |
| A genome-wide scan in affected sibling pairs with idiopathic recurrent miscarriage suggests genetic linkage. | Kolte AM et al. | β | 2011 | β |
| A genome-wide view of mutation rate co-variation using multivariate analyses. | Ananda G et al. | β | 2011 | β |
| A method for detecting IBD regions simultaneously in multiple individuals--with applications to disease genetics. | Moltke I et al. | β | 2011 | β |
| Analysis of human meiotic recombination events with a parent-sibling tracing approach. | Lee YS et al. | β | 2011 | β |
| Ancestral components of admixed genomes in a Mexican cohort. | Johnson NA et al. | β | 2011 | β |
| A novel mitofusin 2 mutation causes canine fetal-onset neuroaxonal dystrophy. | Fyfe JC et al. | β | 2011 | β |
| An SNP-Based Linkage Map for Zebrafish Reveals Sex Determination Loci. | Bradley KM et al. | β | 2011 | β |
| A QTL for genotype by sex interaction for anthropometric measurements in Alaskan Eskimos (GOCADAN Study) on chromosome 19q12-13. | Voruganti VS et al. | β | 2011 | β |
| A simple model for the influence of meiotic conversion tracts on GC content. | Marsolier-Kergoat MC | β | 2011 | β |
| Bases adjacent to mononucleotide repeats show an increased single nucleotide polymorphism frequency in the human genome. | Siddle KJ et al. | β | 2011 | β |
| Bias detection and correction in RNA-Sequencing data. | Zheng W et al. | β | 2011 | β |
| Bonobos fall within the genomic variation of chimpanzees. | Fischer A et al. | β | 2011 | β |
| Consanguinity around the world: what do the genomic data of the HGDP-CEPH diversity panel tell us? | Leutenegger AL et al. | β | 2011 | β |
| CpG site degeneration triggered by the loss of functional constraint created a highly polymorphic macaque drug-metabolizing gene, CYP1A2. | Uno Y et al. | β | 2011 | β |
| Dating the age of admixture via wavelet transform analysis of genome-wide data. | Pugach I et al. | β | 2011 | β |
| DFNB93, a novel locus for autosomal recessive moderate-to-severe hearing impairment. | Tabatabaiefar MA et al. | β | 2011 | β |
| Effects of inversions on within- and between-species recombination and divergence. | Stevison LS et al. | β | 2011 | β |
| Enhanced genetic maps from family-based disease studies: population-specific comparisons. | He C et al. | β | 2011 | β |
| Evolutionary genetic dissection of human interferons. | Manry J et al. | β | 2011 | β |
| Evolution of the genomic recombination rate in murid rodents. | Dumont BL et al. | β | 2011 | β |
| Extensive recombination rate variation in the house mouse species complex inferred from genetic linkage maps. | Dumont BL et al. | β | 2011 | β |
| Familial ventricular aneurysms and septal defects map to chromosome 10p15. | Tremblay N et al. | β | 2011 | β |
| Fast and Accurate Approximation to Significance Tests in Genome-Wide Association Studies. | Zhang Y et al. | β | 2011 | β |
| Fine mapping of candidate regions for bipolar disorder provides strong evidence for susceptibility loci on chromosomes 7q. | Xu H et al. | β | 2011 | β |
| Genetic evidence for archaic admixture in Africa. | Hammer MF et al. | β | 2011 | β |
| Genome-wide analysis of extended pedigrees confirms IL2-IL21 linkage and shows additional regions of interest potentially influencing coeliac disease risk. | Einarsdottir E et al. | β | 2011 | β |
| Genome-wide crossover distribution in Arabidopsis thaliana meiosis reveals sex-specific patterns along chromosomes. | Giraut L et al. | β | 2011 | β |
| Genome-wide linkage analysis of hemodynamic parameters under mental and physical stress in extended Omani Arab pedigrees: the Oman Family Study. | Hassan MO et al. | β | 2011 | β |
| Genome-wide SNP-based linkage analysis for ADNSHL families identifies novel susceptibility loci with positive evidence for linkage. | Park MH et al. | β | 2011 | β |
| Graphene platform for hairpin-DNA-based impedimetric genosensing. | Bonanni A et al. | β | 2011 | β |
| Haplotype sharing test maps genes for familial cardiomyopathies. | van der Zwaag PA et al. | β | 2011 | β |
| Hereditary hypophosphatemic rickets with hypercalciuria and nephrolithiasis-identification of a novel SLC34A3/NaPi-IIc mutation. | Phulwani P et al. | β | 2011 | β |
| High recombination rates and hotspots in a Plasmodium falciparum genetic cross. | Jiang H et al. | β | 2011 | β |
| How to estimate the measurement error variance associated with ancestry proportion estimates. | Divers J et al. | β | 2011 | β |
| Human endogenous retrovirus K106 (HERV-K106) was infectious after the emergence of anatomically modern humans. | Jha AR et al. | β | 2011 | β |
| Identity-by-descent filtering of exome sequence data for disease-gene identification in autosomal recessive disorders. | RΓΆdelsperger C et al. | β | 2011 | β |
| Important characteristics of sequence-specific recombination hotspots in Schizosaccharomyces pombe. | Steiner WW et al. | β | 2011 | β |
| Incomplete lineage sorting patterns among human, chimpanzee, and orangutan suggest recent orangutan speciation and widespread selection. | Hobolth A et al. | β | 2011 | β |
| In silico genotyping of the maize nested association mapping population. | Guo B et al. | β | 2011 | β |
| Integration of the genetic map and genome assembly of fugu facilitates insights into distinct features of genome evolution in teleosts and mammals. | Kai W et al. | β | 2011 | β |
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| On the origin and diffusion of BRCA1 c.5266dupC (5382insC) in European populations. | Hamel N et al. | β | 2011 | β |
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| The loss of the p53 activator HIPK2 is responsible for galectin-3 overexpression in well differentiated thyroid carcinomas. | Lavra L et al. | β | 2011 | β |
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| A comprehensive linkage map of the dog genome. | Wong AK et al. | β | 2010 | β |
| A genetic linkage map of red drum, Sciaenops ocellatus. | Portnoy DS et al. | β | 2010 | β |
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| Analysis of 21 X-chromosomal STRs in an Algerian population sample. | Bekada A et al. | β | 2010 | β |
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| Drosophila melanogaster recombination rate calculator. | Fiston-Lavier AS et al. | β | 2010 | β |
| Evaluation of DLG2 as a positional candidate for disposition index in African-Americans from the IRAS Family Study. | Palmer ND et al. | β | 2010 | β |
| Evidence for rare and common genetic risk variants for schizophrenia at protein kinase C, alpha. | Carroll LS et al. | β | 2010 | β |
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| Female-to-male breeding ratio in modern humans-an analysis based on historical recombinations. | Labuda D et al. | β | 2010 | β |
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| Frequency of and variables associated with the EGFR mutation and its subtypes. | Tanaka T et al. | β | 2010 | β |
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| Genetic association of physically unlinked islands of genomic divergence in incipient species of Anopheles gambiae. | White BJ et al. | β | 2010 | β |
| Genetics of microstructure of cerebral white matter using diffusion tensor imaging. | Kochunov P et al. | β | 2010 | β |
| Genetic variation in APOJ, LPL, and TNFRSF10B affects plasma fatty acid distribution in Alaskan Eskimos. | Voruganti VS et al. | β | 2010 | β |
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| Genome-wide linkage analyses of two repetitive behavior phenotypes in Utah pedigrees with autism spectrum disorders. | Cannon DS et al. | β | 2010 | β |
| Genome-wide linkage in Utah autism pedigrees. | Allen-Brady K et al. | β | 2010 | β |
| Genome-wide linkage using the Social Responsiveness Scale in Utah autism pedigrees. | Coon H et al. | β | 2010 | β |
| Genome-wide search for breast cancer linkage in large Icelandic non-BRCA1/2 families. | Arason A et al. | β | 2010 | β |
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| Human population differentiation is strongly correlated with local recombination rate. | Keinan A et al. | β | 2010 | β |
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| Identification of a novel BRCA1 nucleotide 4803delCC/c.4684delCC mutation and a nucleotide 249T>A/c.130T>A (p.Cys44Ser) mutation in two Greenlandic Inuit families: implications for genetic screening of Greenlandic Inuit families with high risk for breast and/or ovarian cancer. | Hansen TV et al. | β | 2010 | β |
| Identification of copy number variation hotspots in human populations. | Fu W et al. | β | 2010 | β |
| Identifying loci for the overlap between attention-deficit/hyperactivity disorder and autism spectrum disorder using a genome-wide QTL linkage approach. | Nijmeijer JS et al. | β | 2010 | β |
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| Mammalian recombination hot spots: properties, control and evolution. | Paigen K et al. | β | 2010 | β |
| Mechanisms of genomic instabilities underlying two common fragile-site-associated loci, PARK2 and DMD, in germ cell and cancer cell lines. | Mitsui J et al. | β | 2010 | β |
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| Nutritional genomics era: opportunities toward a genome-tailored nutritional regimen. | Costa V et al. | β | 2010 | β |
| Overview of linkage analysis in complex traits. | Bush WS et al. | β | 2010 | β |
| Patterns of recombination activity on mouse chromosome 11 revealed by high resolution mapping. | Billings T et al. | β | 2010 | β |
| Population-based linkage analysis of schizophrenia and bipolar case-control cohorts identifies a potential susceptibility locus on 19q13. | Francks C et al. | β | 2010 | β |
| Population genetic inference from genomic sequence variation. | Pool JE et al. | β | 2010 | β |
| Potentials and limits of pairwise kinship analysis using autosomal short tandem repeat loci. | Nothnagel M et al. | β | 2010 | β |
| Processed pseudogenes are located preferentially in regions of low recombination rates in the human genome. | Liu G et al. | β | 2010 | β |
| Pronounced inter- and intrachromosomal variation in linkage disequilibrium across the zebra finch genome. | Stapley J et al. | β | 2010 | β |
| QTLMAS 2009: simulated dataset. | Coster A et al. | β | 2010 | β |
| Rapid haplotype inference for nuclear families. | Williams AL et al. | β | 2010 | β |
| Rapid, sensitive, and label-free impedimetric detection of a single-nucleotide polymorphism correlated to kidney disease. | Bonanni A et al. | β | 2010 | β |
| Recombinational landscape of porcine X chromosome and individual variation in female meiotic recombination associated with haplotypes of Chinese pigs. | Ma J et al. | β | 2010 | β |
| Recombination-associated sequence homogenization of neighboring Alu elements: signature of nonallelic gene conversion. | Aleshin A et al. | β | 2010 | β |
| Regional differences in recombination hotspots between two chicken populations. | Elferink MG et al. | β | 2010 | β |
| Relationship between gene compactness and base composition in rice and human genome. | Mukhopadhyay P et al. | β | 2010 | β |
| The genomic distribution and local context of coincident SNPs in human and chimpanzee. | Hodgkinson A et al. | β | 2010 | β |
| The recombination landscape of the zebra finch Taeniopygia guttata genome. | BackstrΓΆm N et al. | β | 2010 | β |
| The (r)evolution of SINE versus LINE distributions in primate genomes: sex chromosomes are important. | Kvikstad EM et al. | β | 2010 | β |
| What drives recombination hotspots to repeat DNA in humans? | McVean G | β | 2010 | β |
| X chromosomal recombination--a family study analysing 39 STR markers in German three-generation pedigrees. | Hering S et al. | β | 2010 | β |
| 2q37 as a susceptibility locus for idiopathic basal ganglia calcification (IBGC) in a large South Tyrolean family. | Volpato CB et al. | β | 2009 | β |
| A genome-wide scan for the Sasang constitution in a Korean family suggests significant linkage at chromosomes 8q11.22-23 and 11q22.1-3. | Won HH et al. | β | 2009 | β |
| Agreement among type 2 diabetes linkage studies but a poor correlation with results from genome-wide association studies. | Lillioja S et al. | β | 2009 | β |
| A high density linkage map of the bovine genome. | Arias JA et al. | β | 2009 | β |
| Alu repeats increase local recombination rates. | Witherspoon DJ et al. | β | 2009 | β |
| Analysis of eighteen deletion breakpoints in the parkin gene. | Asakawa S et al. | β | 2009 | β |
| Analysis of genetic variability and whole genome linkage of whole-brain, subcortical, and ependymal hyperintense white matter volume. | Kochunov P et al. | β | 2009 | β |
| Ancestral population genomics: the coalescent hidden Markov model approach. | Dutheil JY et al. | β | 2009 | β |
| Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America. | Kosoy R et al. | β | 2009 | β |
| A new standard genetic map for the laboratory mouse. | Cox A et al. | β | 2009 | β |
| A novel splice site mutation in the RDX gene causes DFNB24 hearing loss in an Iranian family. | Shearer AE et al. | β | 2009 | β |
| A physical map of the papaya genome with integrated genetic map and genome sequence. | Yu Q et al. | β | 2009 | β |
| A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals. | Browning BL et al. | β | 2009 | β |
| Biased gene conversion and the evolution of mammalian genomic landscapes. | Duret L et al. | β | 2009 | β |
| Bivariate genome-wide linkage analysis of femoral bone traits and leg lean mass: Framingham study. | Karasik D et al. | β | 2009 | β |
| Breakpoint mapping and complete analysis of meiotic segregation patterns in three men heterozygous for paracentric inversions. | Bhatt S et al. | β | 2009 | β |
| Broad-scale recombination patterns underlying proper disjunction in humans. | Fledel-Alon A et al. | β | 2009 | β |
| Centrotemporal sharp wave EEG trait in rolandic epilepsy maps to Elongator Protein Complex 4 (ELP4). | Strug LJ et al. | β | 2009 | β |
| Closed-form two-locus sampling distributions: accuracy and universality. | Jenkins PA et al. | β | 2009 | β |
| Collagen type III alpha I is a gastro-oesophageal reflux disease susceptibility gene and a male risk factor for hiatus hernia. | Asling B et al. | β | 2009 | β |
| Comment on "Human-specific gain of function in a developmental enhancer". | Duret L et al. | β | 2009 | β |
| Consensus features of microsatellite distribution: microsatellite contents are universally correlated with recombination rates and are preferentially depressed by centromeres in multicellular eukaryotic genomes. | Guo WJ et al. | β | 2009 | β |
| Detailed recombination studies along chromosome 3B provide new insights on crossover distribution in wheat (Triticum aestivum L.). | Saintenac C et al. | β | 2009 | β |
| Determinants of variation in human serum paraoxonase activity. | Rainwater DL et al. | β | 2009 | β |
| DMD Trp3X nonsense mutation associated with a founder effect in North American families with mild Becker muscular dystrophy. | Flanigan KM et al. | β | 2009 | β |
| Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense. | Barreiro LB et al. | β | 2009 | β |
| Familial autosomal dominant reflex epilepsy triggered by hot water maps to 4q24-q28. | Ratnapriya R et al. | β | 2009 | β |
| Familial thrombocytosis caused by the novel germ-line mutation p.Pro106Leu in the MPL gene. | El-Harith el-HA et al. | β | 2009 | β |
| Fine mapping linkage analysis identifies a novel susceptibility locus for myopia on chromosome 2q37 adjacent to but not overlapping MYP12. | SchΓ€che M et al. | β | 2009 | β |
| Fine mapping of multiple sclerosis susceptibility genes provides evidence of allelic heterogeneity at the IL2RA locus. | Perera D et al. | β | 2009 | β |
| GC content and recombination: reassessing the causal effects for the Saccharomyces cerevisiae genome. | Marsolier-Kergoat MC et al. | β | 2009 | β |
| Gene conversion causing human inherited disease: evidence for involvement of non-B-DNA-forming sequences and recombination-promoting motifs in DNA breakage and repair. | Chuzhanova N et al. | β | 2009 | β |
| Genetic analysis of variation in human meiotic recombination. | Chowdhury R et al. | β | 2009 | β |
| Genetic influence on variation in serum uric acid in American Indians: the strong heart family study. | Voruganti VS et al. | β | 2009 | β |
| Genetic linkage findings for DSM-IV nicotine withdrawal in two populations. | Pergadia ML et al. | β | 2009 | β |
| Genome-wide control of the distribution of meiotic recombination. | Grey C et al. | β | 2009 | β |
| Genome-wide linkage analysis of serum creatinine in three isolated European populations. | Pattaro C et al. | β | 2009 | β |
| Genome-wide linkage and follow-up association study of postpartum mood symptoms. | Mahon PB et al. | β | 2009 | β |
| Genome-wide linkage scan in fuchs endothelial corneal dystrophy. | Afshari NA et al. | β | 2009 | β |
| Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms. | Holmans PA et al. | β | 2009 | β |
| Genome-wide linkage scan reveals three putative breast-cancer-susceptibility loci. | Rosa-Rosa JM et al. | β | 2009 | β |
| Genome-wide linkage screen for stature and body mass index in 3.032 families: evidence for sex- and population-specific genetic effects. | Sammalisto S et al. | β | 2009 | β |
| Genome-wide study of families with absolute pitch reveals linkage to 8q24.21 and locus heterogeneity. | Theusch E et al. | β | 2009 | β |
| Global distribution of genomic diversity underscores rich complex history of continental human populations. | Auton A et al. | β | 2009 | β |
| HapMap methylation-associated SNPs, markers of germline DNA methylation, positively correlate with regional levels of human meiotic recombination. | Sigurdsson MI et al. | β | 2009 | β |
| Hotspots of biased nucleotide substitutions in human genes. | Berglund J et al. | β | 2009 | β |
| Human telomeres that contain (CTAGGG)n repeats show replication dependent instability in somatic cells and the male germline. | Mendez-Bermudez A et al. | β | 2009 | β |
| Hypophosphatemic rickets with hypercalciuria due to mutation in SLC34A3/NaPi-IIc can be masked by vitamin D deficiency and can be associated with renal calcifications. | Kremke B et al. | β | 2009 | β |
| Inference of historical changes in migration rate from the lengths of migrant tracts. | Pool JE et al. | β | 2009 | β |
| Inflammatory bowel disease and mutations affecting the interleukin-10 receptor. | Glocker EO et al. | β | 2009 | β |
| Interaction between a chromosome 10 RET enhancer and chromosome 21 in the Down syndrome-Hirschsprung disease association. | Arnold S et al. | β | 2009 | β |
| Linkage and linkage disequilibrium scan for autism loci in an extended pedigree from Finland. | Kilpinen H et al. | β | 2009 | β |
| Locations and patterns of meiotic recombination in two-generation pedigrees. | Ting JC et al. | β | 2009 | β |
| Locus for familial migrainous vertigo disease maps to chromosome 5q35. | Bahmad F et al. | β | 2009 | β |
| Mapping insertions, deletions and SNPs on Venter's chromosomes. | Costantini M et al. | β | 2009 | β |
| Meiotic recombination in human oocytes. | Cheng EY et al. | β | 2009 | β |
| Methods for human demographic inference using haplotype patterns from genomewide single-nucleotide polymorphism data. | Lohmueller KE et al. | β | 2009 | β |
| Minimal effect of ectopic gene conversion among recent duplicates in four mammalian genomes. | McGrath CL et al. | β | 2009 | β |
| Molecular cytogenetic characterization of variant Philadelphia translocations in chronic myeloid leukemia: genesis and deletion of derivative chromosome 9. | Bennour A et al. | β | 2009 | β |
| Molecular mechanisms for subtelomeric rearrangements associated with the 9q34.3 microdeletion syndrome. | Yatsenko SA et al. | β | 2009 | β |
| Monoallelic expression and tissue specificity are associated with high crossover rates. | Necsulea A et al. | β | 2009 | β |
| Mood-incongruent psychosis in bipolar disorder: conditional linkage analysis shows genome-wide suggestive linkage at 1q32.3, 7p13 and 20q13.31. | Hamshere ML et al. | β | 2009 | β |
| Mu transposon insertion sites and meiotic recombination events co-localize with epigenetic marks for open chromatin across the maize genome. | Liu S et al. | β | 2009 | β |
| Nutrigenomics and cancer. | Ardekani AM et al. | β | 2009 | β |
| Partial correlation analysis indicates causal relationships between GC-content, exon density and recombination rate in the human genome. | Freudenberg J et al. | β | 2009 | β |
| Patterns of autosomal divergence between the human and chimpanzee genomes support an allopatric model of speciation. | Webster MT | β | 2009 | β |
| Population genomic inference of recombination rates and hotspots. | Wang Y et al. | β | 2009 | β |
| Quantitative genetic analysis of the retinal vascular caliber: the Australian Twins Eye Study. | Sun C et al. | β | 2009 | β |
| Recent origin and spread of a common Welsh MAPT splice mutation causing frontotemporal lobar degeneration. | Colombo R et al. | β | 2009 | β |
| Recent positive selection of a human androgen receptor/ectodysplasin A2 receptor haplotype and its relationship to male pattern baldness. | Hillmer AM et al. | β | 2009 | β |
| Recombination and speciation: loci near centromeres are more differentiated than loci near telomeres between subspecies of the European rabbit (Oryctolagus cuniculus). | Carneiro M et al. | β | 2009 | β |
| Relatedness mapping and tracts of relatedness for genome-wide data in the presence of linkage disequilibrium. | Albrechtsen A et al. | β | 2009 | β |
| Relationships between replication timing and GC content of cancer-related genes on human chromosomes 11q and 21q. | Watanabe Y et al. | β | 2009 | β |
| Sequence determinants of human microsatellite variability. | Pemberton TJ et al. | β | 2009 | β |
| Sequences from first settlers reveal rapid evolution in Icelandic mtDNA pool. | Helgason A et al. | β | 2009 | β |
| Sex-specific association of depression and a haplotype in leukotriene A4 hydrolase gene. | Zhao J et al. | β | 2009 | β |
| Significant evidence for linkage to chromosome 5q13 in a genome-wide scan for asthma in an extended pedigree resource. | Teerlink CC et al. | β | 2009 | β |
| The evolutionary enigma of sex. | Otto SP | β | 2009 | β |
| Two-parameter characterization of chromosome-scale recombination rate. | Li W et al. | β | 2009 | β |
| Validation of a single nucleotide polymorphism (SNP) typing assay with 49 SNPs for forensic genetic testing in a laboratory accredited according to the ISO 17025 standard. | BΓΈrsting C et al. | β | 2009 | β |
| Variation in genomic recombination rates among heterogeneous stock mice. | Dumont BL et al. | β | 2009 | β |
| Variation in patterns of human meiotic recombination. | Khil PP et al. | β | 2009 | β |
| Widespread genomic signatures of natural selection in hominid evolution. | McVicker G et al. | β | 2009 | β |
| A frame-shift mutation of PMS2 is a widespread cause of Lynch syndrome. | Clendenning M et al. | β | 2008 | β |
| African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping. | Campbell MC et al. | β | 2008 | β |
| A genome-wide Asian genetic map and ethnic comparison: the GENDISCAN study. | Ju YS et al. | β | 2008 | β |
| A genome wide linkage scan of metacarpal size and geometry in the Framingham Study. | Karasik D et al. | β | 2008 | β |
| A genome-wide scan suggests a susceptibility locus on 5p 13 for nasopharyngeal carcinoma. | Hu LF et al. | β | 2008 | β |
| A genomewide screen for chronic rhinosinusitis genes identifies a locus on chromosome 7q. | Pinto JM et al. | β | 2008 | β |
| A high-density SNP linkage scan with 142 combined subtype ADHD sib pairs identifies linkage regions on chromosomes 9 and 16. | Asherson P et al. | β | 2008 | β |
| Analyses and comparison of accuracy of different genotype imputation methods. | Pei YF et al. | β | 2008 | β |
| Analyses of the National Institute on Aging Late-Onset Alzheimer's Disease Family Study: implication of additional loci. | Lee JH et al. | β | 2008 | β |
| A new susceptibility locus for hypospadias on chromosome 7q32.2-q36.1. | Thai HT et al. | β | 2008 | β |
| A novel DNA sequence database for analyzing human demographic history. | Wall JD et al. | β | 2008 | β |
| A novel locus for ectodermal dysplasia of hairs, nails and teeth type maps to chromosome 18q22.1-22.3. | Tariq M et al. | β | 2008 | β |
| A novel missense mutation in SLC34A3 that causes hereditary hypophosphatemic rickets with hypercalciuria in humans identifies threonine 137 as an important determinant of sodium-phosphate cotransport in NaPi-IIc. | Jaureguiberry G et al. | β | 2008 | β |
| A parallel genetic algorithm to discover patterns in genetic markers that indicate predisposition to multifactorial disease. | Rausch T et al. | β | 2008 | β |
| A regulatory SNP of the BICD1 gene contributes to telomere length variation in humans. | Mangino M et al. | β | 2008 | β |
| Bayesian inference of fine-scale recombination rates using population genomic data. | Wang Y et al. | β | 2008 | β |
| Chromosome 10q harbors a susceptibility locus for bipolar disorder in Ashkenazi Jewish families. | Venken T et al. | β | 2008 | β |
| Chromosome 17q12 variants contribute to risk of early-onset prostate cancer. | Levin AM et al. | β | 2008 | β |
| Cis-acting factors promoting the CAG intergenerational instability in Machado-Joseph disease. | Martins S et al. | β | 2008 | β |
| Common familial colorectal cancer linked to chromosome 7q31: a genome-wide analysis. | Neklason DW et al. | β | 2008 | β |
| CpG dinucleotides and the mutation rate of non-CpG DNA. | Walser JC et al. | β | 2008 | β |
| CpG island density and its correlations with genomic features in mammalian genomes. | Han L et al. | β | 2008 | β |
| Cytogenetic determinants of male fertility. | Martin RH | β | 2008 | β |
| Detection of sharing by descent, long-range phasing and haplotype imputation. | Kong A et al. | β | 2008 | β |
| Dietary change and adaptive evolution of enamelin in humans and among primates. | Kelley JL et al. | β | 2008 | β |
| Dyschromatosis universalis hereditaria: evidence for autosomal recessive inheritance and identification of a new locus on chromosome 12q21-q23. | Stuhrmann M et al. | β | 2008 | β |
| Evidence for a novel x-linked modifier locus for leber hereditary optic neuropathy. | Shankar SP et al. | β | 2008 | β |
| Evolutionary dynamics of the human ABO gene. | Calafell F et al. | β | 2008 | β |
| Evolution of the genomic rate of recombination in mammals. | Dumont BL et al. | β | 2008 | β |
| Evolution of the isochore structure in the scale of chromosome: insight from the mutation bias and fixation bias. | Li MK et al. | β | 2008 | β |
| Expanded high-resolution genetic study of 109 Swedish families with Alzheimer's disease. | SillΓ©n A et al. | β | 2008 | β |
| Exponential decay of GC content detected by strand-symmetric substitution rates influences the evolution of isochore structure. | Karro JE et al. | β | 2008 | β |
| Extreme heterochiasmy and nascent sex chromosomes in European tree frogs. | Berset-BrΓ€ndli L et al. | β | 2008 | β |
| Fine mapping of a locus for nonsyndromic mental retardation on chromosome 19p13. | Nolan DK et al. | β | 2008 | β |
| Fraction of informative recombinations: a heuristic approach to analyze recombination rates. | Lefebvre JF et al. | β | 2008 | β |
| Genetic and phenotypic effects of phonological short-term memory and grammatical morphology in specific language impairment. | Falcaro M et al. | β | 2008 | β |
| Genetic dissection of myopia: evidence for linkage of ocular axial length to chromosome 5q. | Zhu G et al. | β | 2008 | β |
| Genetics of gene expression and its effect on disease. | Emilsson V et al. | β | 2008 | β |
| Genetics of maximal walking speed and skeletal muscle characteristics in older women. | Tiainen KM et al. | β | 2008 | β |
| Genome-wide linkage scan for loci of musical aptitude in Finnish families: evidence for a major locus at 4q22. | Pulli K et al. | β | 2008 | β |
| Genome-wide significance for dense SNP and resequencing data. | Hoggart CJ et al. | β | 2008 | β |
| Genomic inferences on peopling of south Asia. | Majumder PP | β | 2008 | β |
| Heterogeneous nature and distribution of interruptions in dinucleotides may indicate the existence of biased substitutions underlying microsatellite evolution. | Varela MA et al. | β | 2008 | β |
| High frequency of microsatellites in S. cerevisiae meiotic recombination hotspots. | Bagshaw AT et al. | β | 2008 | β |
| High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans. | Coop G et al. | β | 2008 | β |
| Human-macaque comparisons illuminate variation in neutral substitution rates. | Tyekucheva S et al. | β | 2008 | β |
| Identification and analysis of genomic regions with large between-population differentiation in humans. | Myles S et al. | β | 2008 | β |
| Identification and replication of three novel myopia common susceptibility gene loci on chromosome 3q26 using linkage and linkage disequilibrium mapping. | Andrew T et al. | β | 2008 | β |
| Impact of screening kindreds for SDHD p.Cys11X as a common mutation associated with paraganglioma syndrome type 1. | Peczkowska M et al. | β | 2008 | β |
| Linkage analysis of attention deficit hyperactivity disorder. | Faraone SV et al. | β | 2008 | β |
| Linkage disequilibrium between STRPs and SNPs across the human genome. | Payseur BA et al. | β | 2008 | β |
| Linkage of nicotine dependence and smoking behavior on 10q, 7q and 11p in twins with homogeneous genetic background. | Loukola A et al. | β | 2008 | β |
| Linkage to chromosome 1p36 for attention-deficit/hyperactivity disorder traits in school and home settings. | Zhou K et al. | β | 2008 | β |
| Meta-analysis of 23 type 2 diabetes linkage studies from the International Type 2 Diabetes Linkage Analysis Consortium. | Guan W et al. | β | 2008 | β |
| Meta-analysis of genome-wide linkage scans of attention deficit hyperactivity disorder. | Zhou K et al. | β | 2008 | β |
| Metabolic changes in schizophrenia and human brain evolution. | Khaitovich P et al. | β | 2008 | β |
| New insights into human nondisjunction of chromosome 21 in oocytes. | Oliver TR et al. | β | 2008 | β |
| No effect of recombination on the efficacy of natural selection in primates. | Bullaughey K et al. | β | 2008 | β |
| Origins and prevalence of the American Founder Mutation of MSH2. | Clendenning M et al. | β | 2008 | β |
| Pedigree with frontotemporal lobar degeneration--motor neuron disease and Tar DNA binding protein-43 positive neuropathology: genetic linkage to chromosome 9. | Luty AA et al. | β | 2008 | β |
| Performance of the SNPforID 52 SNP-plex assay in paternity testing. | BΓΈrsting C et al. | β | 2008 | β |
| Phylogenetic inference using whole genomes. | Rannala B et al. | β | 2008 | β |
| Polymorphic microsatellite loci for the common marmoset (Callithrix jacchus) designed using a cost- and time-efficient method. | Raveendran M et al. | β | 2008 | β |
| Polymorphisms in 9q32 and TSCOT are linked to cervical cancer in affected sib-pairs with high mean age at diagnosis. | Engelmark MT et al. | β | 2008 | β |
| Population genetic analysis of shotgun assemblies of genomic sequences from multiple individuals. | Hellmann I et al. | β | 2008 | β |
| Prolonged signal-averaged P-wave duration as an intermediate phenotype for familial atrial fibrillation. | Darbar D et al. | β | 2008 | β |
| QTLs identified for P3 amplitude in a non-clinical sample: importance of neurodevelopmental and neurotransmitter genes. | Wright MJ et al. | β | 2008 | β |
| Recombination rates of genes expressed in human tissues. | Kato M et al. | β | 2008 | β |
| Reconstructing the genealogy of a BRCA1 founder mutation by phylogenetic analysis. | Marroni F et al. | β | 2008 | β |
| Sequence information encoded in DNA that may influence long-range chromatin structure correlates with human chromosome functions. | Takasuka TE et al. | β | 2008 | β |
| Sequence variants in the RNF212 gene associate with genome-wide recombination rate. | Kong A et al. | β | 2008 | β |
| Sex-biased evolutionary forces shape genomic patterns of human diversity. | Hammer MF et al. | β | 2008 | β |
| Sites of strong Rec12/Spo11 binding in the fission yeast genome are associated with meiotic recombination and with centromeres. | Ludin K et al. | β | 2008 | β |
| Sperm cross-over activity in regions of the human genome showing extreme breakdown of marker association. | Webb AJ et al. | β | 2008 | β |
| Statistical power analysis of neutrality tests under demographic expansions, contractions and bottlenecks with recombination. | RamΓrez-Soriano A et al. | β | 2008 | β |
| Survey of microsatellite clustering in eight fully sequenced species sheds light on the origin of compound microsatellites. | Kofler R et al. | β | 2008 | β |
| The genomic distribution of intraspecific and interspecific sequence divergence of human segmental duplications relative to human/chimpanzee chromosomal rearrangements. | Marques-Bonet T et al. | β | 2008 | β |
| The human pseudoautosomal regions: a review for genetic epidemiologists. | Flaquer A et al. | β | 2008 | β |
| The impact of recombination on nucleotide substitutions in the human genome. | Duret L et al. | β | 2008 | β |
| The opossum genome: insights and opportunities from an alternative mammal. | Samollow PB | β | 2008 | β |
| The recombinational anatomy of a mouse chromosome. | Paigen K et al. | β | 2008 | β |
| Toward a selection theory of molecular evolution. | Hahn MW | β | 2008 | β |
| Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy. | Majewski T et al. | β | 2008 | β |
| Unlabeled hairpin-DNA probe for the detection of single-nucleotide mismatches by electrochemical impedance spectroscopy. | Wang Y et al. | β | 2008 | β |
| A genome-wide linkage study of GAW15 gene expression data. | Kan D et al. | β | 2007 | β |
| A genomewide single-nucleotide-polymorphism panel for Mexican American admixture mapping. | Tian C et al. | β | 2007 | β |
| Allelic association and recombination hotspots in the mucin gene (MUC) complex on chromosome 11p15.5. | Rousseau K et al. | β | 2007 | β |
| A macaque's-eye view of human insertions and deletions: differences in mechanisms. | Kvikstad EM et al. | β | 2007 | β |
| A meiotic linkage map of the silver fox, aligned and compared to the canine genome. | Kukekova AV et al. | β | 2007 | β |
| Analysis of meiotic recombination in 22q11.2, a region that frequently undergoes deletions and duplications. | Torres-Juan L et al. | β | 2007 | β |
| An evolutionary view of human recombination. | Coop G et al. | β | 2007 | β |
| A new approach for using genome scans to detect recent positive selection in the human genome. | Tang K et al. | β | 2007 | β |
| A new approach to estimate parameters of speciation models with application to apes. | Becquet C et al. | β | 2007 | β |
| A novel locus for autosomal recessive nonsyndromic hearing impairment, DFNB63, maps to chromosome 11q13.2-q13.4. | Kalay E et al. | β | 2007 | β |
| A range of simple summary genome-wide statistics for detecting genetic linkage using high density marker data. | Saunders IW et al. | β | 2007 | β |
| A second-generation combined linkage physical map of the human genome. | Matise TC et al. | β | 2007 | β |
| A third-generation microsatellite-based linkage map of the honey bee, Apis mellifera, and its comparison with the sequence-based physical map. | Solignac M et al. | β | 2007 | β |
| Autosomal linkage analysis of a Japanese single multiplex schizophrenia pedigree reveals two candidate loci on chromosomes 4q and 3q. | Kaneko N et al. | β | 2007 | β |
| Biased clustered substitutions in the human genome: the footprints of male-driven biased gene conversion. | Dreszer TR et al. | β | 2007 | β |
| Bivariate linkage study of proximal hip geometry and body size indices: the Framingham study. | Karasik D et al. | β | 2007 | β |
| Cis- and trans-acting elements regulate the mouse Psmb9 meiotic recombination hotspot. | Baudat F et al. | β | 2007 | β |
| Combined genome scans for body stature in 6,602 European twins: evidence for common Caucasian loci. | Perola M et al. | β | 2007 | β |
| Comprehensive linkage and linkage heterogeneity analysis of 4344 sibling pairs affected with hypertension from the Family Blood Pressure Program. | Greenwood TA et al. | β | 2007 | β |
| Convergent adaptation of human lactase persistence in Africa and Europe. | Tishkoff SA et al. | β | 2007 | β |
| Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes. | GΓΆring HH et al. | β | 2007 | β |
| Dissecting the locus heterogeneity of autism: significant linkage to chromosome 12q14. | Ma DQ et al. | β | 2007 | β |
| Distinct linkage disequilibrium (LD) runs of single nucleotide polymorphisms and microsatellite markers; implications for use of mixed marker haplotypes in LD-based mapping. | Lee KA et al. | β | 2007 | β |
| Effects of recombination rate on human endogenous retrovirus fixation and persistence. | Katzourakis A et al. | β | 2007 | β |
| Efficient multilocus association testing for whole genome association studies using localized haplotype clustering. | Browning BL et al. | β | 2007 | β |
| Elevated rates of sister chromatid exchange at chromosome ends. | Rudd MK et al. | β | 2007 | β |
| Enrichment of HapMap recombination hotspot predictions around human nervous system genes: evidence for positive selection? | Freudenberg J et al. | β | 2007 | β |
| Epigenetic control of the critical region for premature ovarian failure on autosomal genes translocated to the X chromosome: a hypothesis. | Rizzolio F et al. | β | 2007 | β |
| Establishment of high-resolution FISH mapping system and its application for molecular cytogenetic characterization of chromosomes in newt, Cynops pyrrhogaster (Urodela, Amphibia). | Murakami T et al. | β | 2007 | β |
| Estimating genotyping error rates from Mendelian errors in SNP array genotypes and their impact on inference. | Saunders IW et al. | β | 2007 | β |
| Estimating meiotic gene conversion rates from population genetic data. | Gay J et al. | β | 2007 | β |
| Evidence for large inversion polymorphisms in the human genome from HapMap data. | Bansal V et al. | β | 2007 | β |
| Evolution of gene sequence in response to chromosomal location. | DΓaz-Castillo C et al. | β | 2007 | β |
| Family-based association tests for genomewide association scans. | Chen WM et al. | β | 2007 | β |
| Fine-mapping the putative chromosome 17q21-22 prostate cancer susceptibility gene to a 10 cM region based on linkage analysis. | Lange EM et al. | β | 2007 | β |
| Gender differences in germ-cell mutagenesis and genetic risk. | Eichenlaub-Ritter U et al. | β | 2007 | β |
| Gender effects on the incidence of aneuploidy in mammalian germ cells. | Pacchierotti F et al. | β | 2007 | β |
| Genetic evidence for ongoing balanced selection at human DNA repair genes ERCC8, FANCC, and RAD51C. | Wang ET et al. | β | 2007 | β |
| Genetic exchange in 2La inversion heterokaryotypes of Anopheles gambiae. | Stump AD et al. | β | 2007 | β |
| Genetic linkage to chromosome 22q12 for a heavy-smoking quantitative trait in two independent samples. | Saccone SF et al. | β | 2007 | β |
| Genetics of recurrent early-onset major depression (GenRED): final genome scan report. | Holmans P et al. | β | 2007 | β |
| Genomewide high-density SNP linkage analysis of non-BRCA1/2 breast cancer families identifies various candidate regions and has greater power than microsatellite studies. | Gonzalez-Neira A et al. | β | 2007 | β |
| Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease. | Hamshere ML et al. | β | 2007 | β |
| Genome-wide linkage analysis of pulmonary function in families of children with asthma in Costa Rica. | Hersh CP et al. | β | 2007 | β |
| Genome-wide linkage scan for breast cancer susceptibility loci in Swedish hereditary non-BRCA1/2 families: suggestive linkage to 10q23.32-q25.3. | Bergman A et al. | β | 2007 | β |
| Genome-wide scan for serum ghrelin detects linkage on chromosome 1p36 in Hispanic children: results from the Viva La Familia study. | Voruganti VS et al. | β | 2007 | β |
| Genome-wide scans meta-analysis for pulse pressure. | Zintzaras E et al. | β | 2007 | β |
| Genomic relationships and speciation times of human, chimpanzee, and gorilla inferred from a coalescent hidden Markov model. | Hobolth A et al. | β | 2007 | β |
| Genotype x adiposity interaction linkage analyses reveal a locus on chromosome 1 for lipoprotein-associated phospholipase A2, a marker of inflammation and oxidative stress. | Diego VP et al. | β | 2007 | β |
| Homozygosity haplotype allows a genomewide search for the autosomal segments shared among patients. | Miyazawa H et al. | β | 2007 | β |
| Identifying genes underlying skin pigmentation differences among human populations. | Myles S et al. | β | 2007 | β |
| Improving estimates of genetic maps: a meta-analysis-based approach. | Stewart WC | β | 2007 | β |
| Increased familial risk and genomewide significant linkage for Alzheimer's disease with psychosis. | Hollingworth P et al. | β | 2007 | β |
| Interactions among genes in the ErbB-Neuregulin signalling network are associated with increased susceptibility to schizophrenia. | Benzel I et al. | β | 2007 | β |
| Isochores and replication time zones: a perfect match. | Schmegner C et al. | β | 2007 | β |
| Linkage disequilibrium in wild mice. | Laurie CC et al. | β | 2007 | β |
| Localizing recent adaptive evolution in the human genome. | Williamson SH et al. | β | 2007 | β |
| Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans. | MacArthur DG et al. | β | 2007 | β |
| Mammalian meiotic recombination hot spots. | Arnheim N et al. | β | 2007 | β |
| Mapping of a novel type III variant of Knobloch syndrome (KNO3) to chromosome 17q11.2. | Khaliq S et al. | β | 2007 | β |
| Mapping of meiotic single-stranded DNA reveals double-stranded-break hotspots near centromeres and telomeres. | Blitzblau HG et al. | β | 2007 | β |
| MareyMap: an R-based tool with graphical interface for estimating recombination rates. | Rezvoy C et al. | β | 2007 | β |
| Maternal history of type 2 diabetes is associated with diabetic nephropathy in type 1 diabetic patients. | Hadjadj S et al. | β | 2007 | β |
| Molecular characterization of a novel X-linked syndrome involving developmental delay and deafness. | Hildebrand MS et al. | β | 2007 | β |
| Mutations in the UBIAD1 gene, encoding a potential prenyltransferase, are causal for Schnyder crystalline corneal dystrophy. | Orr A et al. | β | 2007 | β |
| Nucleotide variation in wild and inbred mice. | Salcedo T et al. | β | 2007 | β |
| On recombination-induced multiple and simultaneous coalescent events. | Davies JL et al. | β | 2007 | β |
| On the association between chromosomal rearrangements and genic evolution in humans and chimpanzees. | Marques-Bonet T et al. | β | 2007 | β |
| PAK3 related mental disability: further characterization of the phenotype. | Peippo M et al. | β | 2007 | β |
| Patterns of population differentiation of candidate genes for cardiovascular disease. | Kullo IJ et al. | β | 2007 | β |
| Playing hide and seek with mammalian meiotic crossover hotspots. | Buard J et al. | β | 2007 | β |
| Polymorphic variation in human meiotic recombination. | Cheung VG et al. | β | 2007 | β |
| Population genetics of anthelmintic resistance in parasitic nematodes. | Gilleard JS et al. | β | 2007 | β |
| Proximal hip geometry is linked to several chromosomal regions: genome-wide linkage results from the Framingham Osteoporosis Study. | Demissie S et al. | β | 2007 | β |
| Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering. | Browning SR et al. | β | 2007 | β |
| Rapid evolution of primate ESX1, an X-linked placenta- and testis-expressed homeobox gene. | Wang X et al. | β | 2007 | β |
| Rate of recombinational deletion among human endogenous retroviruses. | Belshaw R et al. | β | 2007 | β |
| Recent acceleration of human adaptive evolution. | Hawks J et al. | β | 2007 | β |
| Recent and ongoing selection in the human genome. | Nielsen R et al. | β | 2007 | β |
| Recombination rate estimation in the presence of hotspots. | Auton A et al. | β | 2007 | β |
| Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer. | Kim K et al. | β | 2007 | β |
| Refinement of a locus for autosomal dominant hereditary motor and sensory neuropathy with proximal dominancy (HMSN-P) and genetic heterogeneity. | Maeda K et al. | β | 2007 | β |
| Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution. | Helgason A et al. | β | 2007 | β |
| Regulating double-stranded DNA break repair towards crossover or non-crossover during mammalian meiosis. | Baudat F et al. | β | 2007 | β |
| Replication of reported linkages for dyslexia and spelling and suggestive evidence for novel regions on chromosomes 4 and 17. | Bates TC et al. | β | 2007 | β |
| Reverse polarization in amino acid and nucleotide substitution patterns between human-mouse orthologs of two compositional extrema. | Bag SK et al. | β | 2007 | β |
| Selection against LINE-1 retrotransposons results principally from their ability to mediate ectopic recombination. | Song M et al. | β | 2007 | β |
| Sex: differences in mutation, recombination, selection, gene flow, and genetic drift. | Hedrick PW | β | 2007 | β |
| Sex-specific crossover distributions and variations in interference level along Arabidopsis thaliana chromosome 4. | Drouaud J et al. | β | 2007 | β |
| Sex-specific linkage to total serum immunoglobulin E in families of children with asthma in Costa Rica. | Raby BA et al. | β | 2007 | β |
| Significant linkage to airway responsiveness on chromosome 12q24 in families of children with asthma in Costa Rica. | CeledΓ³n JC et al. | β | 2007 | β |
| Simple models of genomic variation in human SNP density. | Sainudiin R et al. | β | 2007 | β |
| Strong evidence of a genetic determinant for mammographic density, a major risk factor for breast cancer. | Vachon CM et al. | β | 2007 | β |
| Suggestive genetic linkage to chromosome 11p11.2-q12.2 in hereditary prostate cancer families with primary kidney cancer. | Johanneson B et al. | β | 2007 | β |
| Summary of Genetic Analysis Workshop 15: Group 9 linkage analysis of the CEPH expression data. | Wijsman EM et al. | β | 2007 | β |
| Sympatric speciation as intrinsic property of the expanding population. | Waga W et al. | β | 2007 | β |
| The Fusarium graminearum genome reveals a link between localized polymorphism and pathogen specialization. | Cuomo CA et al. | β | 2007 | β |
| The genetic study of three population microisolates in South Tyrol (MICROS): study design and epidemiological perspectives. | Pattaro C et al. | β | 2007 | β |
| The human genomic melting map. | Liu F et al. | β | 2007 | β |
| The origin of trisomy 13. | Hall HE et al. | β | 2007 | β |
| The rate, not the spectrum, of base pair substitutions changes at a GC-content transition in the human NF1 gene region: implications for the evolution of the mammalian genome structure. | Schmegner C et al. | β | 2007 | β |
| Variation in estimated recombination rates across human populations. | Graffelman J et al. | β | 2007 | β |
| A common variant associated with prostate cancer in European and African populations. | Amundadottir LT et al. | β | 2006 | β |
| A genome-wide distribution of 8-oxoguanine correlates with the preferred regions for recombination and single nucleotide polymorphism in the human genome. | Ohno M et al. | β | 2006 | β |
| A genome wide linkage search for breast cancer susceptibility genes. | Smith P et al. | β | 2006 | β |
| A genome-wide scan for attention-deficit/hyperactivity disorder in 155 German sib-pairs. | Hebebrand J et al. | β | 2006 | β |
| A genomewide single-nucleotide-polymorphism panel with high ancestry information for African American admixture mapping. | Tian C et al. | β | 2006 | β |
| A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. | de Bakker PI et al. | β | 2006 | β |
| A high-resolution map of Arabidopsis recombinant inbred lines by whole-genome exon array hybridization. | Singer T et al. | β | 2006 | β |
| A high-resolution single nucleotide polymorphism genetic map of the mouse genome. | Shifman S et al. | β | 2006 | β |
| A high-resolution survey of deletion polymorphism in the human genome. | Conrad DF et al. | β | 2006 | β |
| A linkage map for brown trout (Salmo trutta): chromosome homeologies and comparative genome organization with other salmonid fish. | Gharbi K et al. | β | 2006 | β |
| A linkage study of academic skills defined by the Queensland core skills test. | Wainwright MA et al. | β | 2006 | β |
| Allele frequency matching between SNPs reveals an excess of linkage disequilibrium in genic regions of the human genome. | Eberle MA et al. | β | 2006 | β |
| A locus for autosomal dominant accessory auricular anomaly maps to 14q11.2-q12. | Yang Y et al. | β | 2006 | β |
| A map of recent positive selection in the human genome. | Voight BF et al. | β | 2006 | β |
| A multimarker regression-based test of linkage for affected sib-pairs at two linked loci. | Barber MJ et al. | β | 2006 | β |
| A multistep mutation mechanism drives the evolution of the CAG repeat at MJD/SCA3 locus. | Martins S et al. | β | 2006 | β |
| Analysis of a Scottish founder effect narrows the TAPVR-1 gene interval to chromosome 4q12. | Bleyl SB et al. | β | 2006 | β |
| Analysis of the DNA sequence and duplication history of human chromosome 15. | Zody MC et al. | β | 2006 | β |
| A new method for detecting human recombination hotspots and its applications to the HapMap ENCODE data. | Li J et al. | β | 2006 | β |
| A new perspective on isochore evolution. | Duret L et al. | β | 2006 | β |
| An initial genetic linkage map of the rhesus macaque (Macaca mulatta) genome using human microsatellite loci. | Rogers J et al. | β | 2006 | β |
| An integrated genetic map for linkage analysis. | Duffy DL | β | 2006 | β |
| A novel TECTA mutation in a Dutch DFNA8/12 family confirms genotype-phenotype correlation. | Plantinga RF et al. | β | 2006 | β |
| A powerful method of combining measures of association and Hardy-Weinberg disequilibrium for fine-mapping in case-control studies. | Song K et al. | β | 2006 | β |
| A second-generation genetic linkage map of the baboon (Papio hamadryas) genome. | Cox LA et al. | β | 2006 | β |
| Assignment of rainbow trout linkage groups to specific chromosomes. | Phillips RB et al. | β | 2006 | β |
| Assignment of zebrafish genetic linkage groups to chromosomes. | Phillips RB et al. | β | 2006 | β |
| Association of poly-purine/poly-pyrimidine sequences with meiotic recombination hot spots. | Bagshaw AT et al. | β | 2006 | β |
| A third-pass genome scan in panic disorder: evidence for multiple susceptibility loci. | Fyer AJ et al. | β | 2006 | β |
| A worldwide survey of haplotype variation and linkage disequilibrium in the human genome. | Conrad DF et al. | β | 2006 | β |
| Basilar-type migraine: clinical, epidemiologic, and genetic features. | Kirchmann M et al. | β | 2006 | β |
| Bias of selection on human copy-number variants. | Nguyen DQ et al. | β | 2006 | β |
| Characterization of a susceptibility locus for SLE, SLEB5, on chromosome 4p14-13. | Johansson CM et al. | β | 2006 | β |
| Chromosomal rearrangements in Xq and premature ovarian failure: mapping of 25 new cases and review of the literature. | Rizzolio F et al. | β | 2006 | β |
| Clinical applications of whole-genome association studies: future applications at the bedside. | Motsinger AA et al. | β | 2006 | β |
| Cochlear implants for DFNA17 deafness. | Hildebrand MS et al. | β | 2006 | β |
| Combined linkage and association analyses of the 124-bp allele of marker D2S2944 with anxiety, depression, neuroticism and major depression. | Beem AL et al. | β | 2006 | β |
| Comparison of human (and other) genome browsers. | Furey TS | β | 2006 | β |
| Comparison of methods incorporating quantitative covariates into affected sib pair linkage analysis. | Tsai HJ et al. | β | 2006 | β |
| Constructing the parental linkage phase and the genetic map over distances <1 cM using pooled haploid DNA. | Gasbarra D et al. | β | 2006 | β |
| Contrasting multi-site genotypic distributions among discordant quantitative phenotypes: the APOA1/C3/A4/A5 gene cluster and cardiovascular disease risk factors. | Payseur BA et al. | β | 2006 | β |
| Contrasting patterns of introgression at X-linked loci across the hybrid zone between subspecies of the European rabbit (Oryctolagus cuniculus). | Geraldes A et al. | β | 2006 | β |
| Covariate analysis of late-onset Alzheimer disease refines the chromosome 12 locus. | Liang X et al. | β | 2006 | β |
| Crossover frequency and synaptonemal complex length: their variability and effects on human male meiosis. | Codina-Pascual M et al. | β | 2006 | β |
| Development of two multiplex PCR systems for the analysis of 12 X-chromosomal STR loci in a northwestern Italian population sample. | Robino C et al. | β | 2006 | β |
| DNA sequence and analysis of human chromosome 8. | Nusbaum C et al. | β | 2006 | β |
| Estimating recombination rates from single-nucleotide polymorphisms using summary statistics. | Padhukasahasram B et al. | β | 2006 | β |
| Evaluating HapMap SNP data transferability in a large-scale genotyping project involving 175 cancer-associated genes. | Ribas G et al. | β | 2006 | β |
| Evidence for recent positive selection at the human AIM1 locus in a European population. | Soejima M et al. | β | 2006 | β |
| Evidence that the adaptive allele of the brain size gene microcephalin introgressed into Homo sapiens from an archaic Homo lineage. | Evans PD et al. | β | 2006 | β |
| Functional domains of the BACE1 and BACE2 promoters and mechanisms of transcriptional suppression of the BACE2 promoter in normal neuronal cells. | Lahiri DK et al. | β | 2006 | β |
| GC content evolution of the human and mouse genomes: insights from the study of processed pseudogenes in regions of different recombination rates. | Khelifi A et al. | β | 2006 | β |
| Gene flow's effect on the genetic architecture of a local adaptation and its consequences for QTL analyses. | Griswold CK | β | 2006 | β |
| Gene losses during human origins. | Wang X et al. | β | 2006 | β |
| Genetic association studies in cancer: good, bad or no longer ugly? | Savage SA et al. | β | 2006 | β |
| Genetic heterogeneity of synpolydactyly: a novel locus SPD3 maps to chromosome 14q11.2-q12. | Malik S et al. | β | 2006 | β |
| Genetic linkage and association analysis for loneliness in Dutch twin and sibling pairs points to a region on chromosome 12q23-24. | Boomsma DI et al. | β | 2006 | β |
| Genetic mapping of disposition index and acute insulin response loci on chromosome 11q. The Insulin Resistance Atherosclerosis Study (IRAS) Family Study. | Palmer ND et al. | β | 2006 | β |
| Genome scan on Swedish Alzheimer's disease families. | SillΓ©n A et al. | β | 2006 | β |
| Genomewide linkage scan of 409 European-ancestry and African American families with schizophrenia: suggestive evidence of linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the combined sample. | Suarez BK et al. | β | 2006 | β |
| Genome-wide linkage scan to identify Loci for age at first cigarette in Dutch sibling pairs. | Vink JM et al. | β | 2006 | β |
| Genomewide scan for real-word reading subphenotypes of dyslexia: novel chromosome 13 locus and genetic complexity. | Igo RP et al. | β | 2006 | β |
| Genome-wide scan of IQ finds significant linkage to a quantitative trait locus on 2q. | Luciano M et al. | β | 2006 | β |
| Genome wide significant linkage in schizophrenia conditioning on occurrence of depressive episodes. | Hamshere ML et al. | β | 2006 | β |
| Genomic and evolutionary insights into genes encoding proteins with single amino acid repeats. | Siwach P et al. | β | 2006 | β |
| Genomic signatures of positive selection in humans and the limits of outlier approaches. | Kelley JL et al. | β | 2006 | β |
| Genotyping of simple sequence repeats--factors implicated in shadow band generation revisited. | Olejniczak M et al. | β | 2006 | β |
| Global landscape of recent inferred Darwinian selection for Homo sapiens. | Wang ET et al. | β | 2006 | β |
| Haplotype block structure is conserved across mammals. | Guryev V et al. | β | 2006 | β |
| High-density mapping and follow-up studies on chromosomal regions 1, 3, 6, 12, 13 and 17 in 28 families with chronic lymphocytic leukaemia. | Ng D et al. | β | 2006 | β |
| High recombination frequency creates genotypic diversity in colonies of the leaf-cutting ant Acromyrmex echinatior. | SirviΓΆ A et al. | β | 2006 | β |
| High-resolution association mapping of quantitative trait loci: a population-based approach. | Fan R et al. | β | 2006 | β |
| High-resolution recombination patterns in a region of human chromosome 21 measured by sperm typing. | Tiemann-Boege I et al. | β | 2006 | β |
| Human chromosome 11 DNA sequence and analysis including novel gene identification. | Taylor TD et al. | β | 2006 | β |
| Human F7 sequence is split into three deep clades that are related to FVII plasma levels. | Sabater-Lleal M et al. | β | 2006 | β |
| Human imprinted chromosomal regions are historical hot-spots of recombination. | Sandovici I et al. | β | 2006 | β |
| Human polymorphism around recombination hotspots. | Spencer CC | β | 2006 | β |
| Identification of chromosomal regions linked to premature myocardial infarction: a meta-analysis of whole-genome searches. | Zintzaras E et al. | β | 2006 | β |
| Identification of susceptibility loci for cervical carcinoma by genome scan of affected sib-pairs. | Engelmark MT et al. | β | 2006 | β |
| Immunogenomics: molecular hide and seek. | Miretti MM et al. | β | 2006 | β |
| Improving estimates of genetic maps: a maximum likelihood approach. | Stewart WC et al. | β | 2006 | β |
| Increased activity of coagulation factor XII (Hageman factor) causes hereditary angioedema type III. | Cichon S et al. | β | 2006 | β |
| Increased support for linkage of a novel locus on chromosome 5q13 for essential hypertension in the British Genetics of Hypertension Study. | Munroe PB et al. | β | 2006 | β |
| Inference about recombination from haplotype data: lower bounds and recombination hotspots. | Bafna V et al. | β | 2006 | β |
| Insights into recombination from population genetic variation. | Hellenthal G et al. | β | 2006 | β |
| Linkage analyses of event-related potential slow wave phenotypes recorded in a working memory task. | Hansell NK et al. | β | 2006 | β |
| Linkage analysis localises a Kartagener syndrome gene to a 3.5 cM region on chromosome 15q24-25. | Geremek M et al. | β | 2006 | β |
| Long homopurine*homopyrimidine sequences are characteristic of genes expressed in brain and the pseudoautosomal region. | Bacolla A et al. | β | 2006 | β |
| Maternal polymorphisms 677C-T and 1298A-C of MTHFR, and 66A-G MTRR genes: is there any relationship between polymorphisms of the folate pathway, maternal homocysteine levels, and the risk for having a child with Down syndrome? | MartΓnez-FrΓas ML et al. | β | 2006 | β |
| Meiosis in mammals: recombination, non-disjunction and the environment. | Hunt PA | β | 2006 | β |
| Modeling haplotype block variation using Markov chains. | Greenspan G et al. | β | 2006 | β |
| Molecular evolution of 5' flanking regions of 87 candidate genes for atherosclerotic cardiovascular disease. | Ding K et al. | β | 2006 | β |
| Molecular features of meiotic recombination hot spots. | Nishant KT et al. | β | 2006 | β |
| Novel sequence variants in the TMIE gene in families with autosomal recessive nonsyndromic hearing impairment. | Santos RL et al. | β | 2006 | β |
| Nucleotide variation and haplotype diversity in a 10-kb noncoding region in three continental human populations. | Zhao Z et al. | β | 2006 | β |
| Phenotype-stratified genetic linkage study demonstrates that IBD2 is an extensive ulcerative colitis locus. | Achkar JP et al. | β | 2006 | β |
| Pooled genome linkage scan of aggressive prostate cancer: results from the International Consortium for Prostate Cancer Genetics. | Schaid DJ et al. | β | 2006 | β |
| Positive selection on gene expression in the human brain. | Khaitovich P et al. | β | 2006 | β |
| Possible ancestral structure in human populations. | Plagnol V et al. | β | 2006 | β |
| Quantification of homozygosity in consanguineous individuals with autosomal recessive disease. | Woods CG et al. | β | 2006 | β |
| Reduced bone mineral density and hyaloid vasculature remnants in a consanguineous recessive FEVR family with a mutation in LRP5. | Downey LM et al. | β | 2006 | β |
| Refinement of the locus for hereditary congenital facial palsy on chromosome 3q21 in two unrelated families and screening of positional candidate genes. | Michielse CB et al. | β | 2006 | β |
| Replicated linkage for eye color on 15q using comparative ratings of sibling pairs. | Posthuma D et al. | β | 2006 | β |
| Response to paper by Molloy et al.: linkage on 21q and 7q in autism subset with regression. | Parr JR et al. | β | 2006 | β |
| Sex-specific genetic architecture of asthma-associated quantitative trait loci in a founder population. | Ober C et al. | β | 2006 | β |
| Significant positive correlation between the recombination rate and GC content in the human pseudoautosomal region. | Chen JF et al. | β | 2006 | β |
| SLC34A3 mutations in patients with hereditary hypophosphatemic rickets with hypercalciuria predict a key role for the sodium-phosphate cotransporter NaPi-IIc in maintaining phosphate homeostasis. | Bergwitz C et al. | β | 2006 | β |
| Spectrum of mutations in mut methylmalonic acidemia and identification of a common Hispanic mutation and haplotype. | Worgan LC et al. | β | 2006 | β |
| Strong and weak male mutation bias at different sites in the primate genomes: insights from the human-chimpanzee comparison. | Taylor J et al. | β | 2006 | β |
| Strong correlation between meiotic crossovers and haplotype structure in a 2.5-Mb region on the long arm of chromosome 21. | Greenawalt DM et al. | β | 2006 | β |
| Strong regional biases in nucleotide substitution in the chicken genome. | Webster MT et al. | β | 2006 | β |
| The CACNA1A and ATP1A2 genes are not involved in dominantly inherited migraine with aura. | Kirchmann M et al. | β | 2006 | β |
| The distribution and causes of meiotic recombination in the human genome. | Myers S et al. | β | 2006 | β |
| The DNA sequence and biological annotation of human chromosome 1. | Gregory SG et al. | β | 2006 | β |
| The DNA sequence, annotation and analysis of human chromosome 3. | Muzny DM et al. | β | 2006 | β |
| The effective size of the Icelandic population and the prospects for LD mapping: inference from unphased microsatellite markers. | Bataillon T et al. | β | 2006 | β |
| The elusive multiple self-healing squamous epithelioma (MSSE) gene: further mapping, analysis of candidates, and loss of heterozygosity. | Bose S et al. | β | 2006 | β |
| The influence of recombination on human genetic diversity. | Spencer CC et al. | β | 2006 | β |
| The mapping of DFNB62, a new locus for autosomal recessive non-syndromic hearing impairment, to chromosome 12p13.2-p11.23. | Ali G et al. | β | 2006 | β |
| The prion protein gene in humans revisited: lessons from a worldwide resequencing study. | Soldevila M et al. | β | 2006 | β |
| The synaptonemal complex and meiotic recombination in humans: new approaches to old questions. | Vallente RU et al. | β | 2006 | β |
| Using genomic inbreeding coefficient estimates for homozygosity mapping of rare recessive traits: application to Taybi-Linder syndrome. | Leutenegger AL et al. | β | 2006 | β |
| Using sex-averaged genetic maps in multipoint linkage analysis when identity-by-descent status is incompletely known. | Fingerlin TE et al. | β | 2006 | β |
| Variable molecular clocks in hominoids. | Elango N et al. | β | 2006 | β |
| Variation in crossing-over rates across chromosome 4 of Arabidopsis thaliana reveals the presence of meiotic recombination "hot spots". | Drouaud J et al. | β | 2006 | β |
| Weak selection and recent mutational changes influence polymorphic synonymous mutations in humans. | Comeron JM | β | 2006 | β |
| A combined genomewide linkage scan of 1,233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics. | Xu J et al. | β | 2005 | β |
| A comparative analysis of the rainbow trout genome with 2 other species of fish (Arctic charr and Atlantic salmon) within the tetraploid derivative Salmonidae family (subfamily: Salmoninae). | Danzmann RG et al. | β | 2005 | β |
| A comprehensive expressed sequence tag linkage map for tiger salamander and Mexican axolotl: enabling gene mapping and comparative genomics in Ambystoma. | Smith JJ et al. | β | 2005 | β |
| A fine-scale map of recombination rates and hotspots across the human genome. | Myers S et al. | β | 2005 | β |
| A genome scan for parent-of-origin linkage effects in alcoholism. | Liu XQ et al. | β | 2005 | β |
| A genome scan in multigenerational families with dyslexia: Identification of a novel locus on chromosome 2q that contributes to phonological decoding efficiency. | Raskind WH et al. | β | 2005 | β |
| A genomewide linkage study of 1,933 families affected by premature coronary artery disease: The British Heart Foundation (BHF) Family Heart Study. | Samani NJ et al. | β | 2005 | β |
| A genomewide scan for intelligence identifies quantitative trait loci on 2q and 6p. | Posthuma D et al. | β | 2005 | β |
| A haplotype map of the human genome. | International HapMap Consortium | β | 2005 | β |
| A high-density screen for linkage in multiple sclerosis. | Sawcer S et al. | β | 2005 | β |
| Allegro version 2. | Gudbjartsson DF et al. | β | 2005 | β |
| Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors. | Sutcliffe JS et al. | β | 2005 | β |
| A male-specific quantitative trait locus on 1p21 controlling human stature. | Sammalisto S et al. | β | 2005 | β |
| A map of the human genome in linkage disequilibrium units. | Tapper W et al. | β | 2005 | β |
| Anatomy of a founder effect: myotonic dystrophy in Northeastern Quebec. | Yotova V et al. | β | 2005 | β |
| Ancient haplotypes of the HLA Class II region. | Raymond CK et al. | β | 2005 | β |
| A novel 3-bp deletion in the PANK2 gene of Dutch patients with pantothenate kinase-associated neurodegeneration: evidence for a founder effect. | Rump P et al. | β | 2005 | β |
| A novel autosomal recessive nonsyndromic hearing impairment locus (DFNB42) maps to chromosome 3q13.31-q22.3. | Aslam M et al. | β | 2005 | β |
| A novel D458V mutation in the SANS PDZ binding motif causes atypical Usher syndrome. | Kalay E et al. | β | 2005 | β |
| A novel locus for autosomal-dominant dilated cardiomyopathy maps to chromosome 7q22.3-31.1. | SchΓΆnberger J et al. | β | 2005 | β |
| A novel method with improved power to detect recombination hotspots from polymorphism data reveals multiple hotspots in human genes. | Fearnhead P et al. | β | 2005 | β |
| A novel X-linked form of congenital fiber-type disproportion. | Clarke NF et al. | β | 2005 | β |
| A panel of 20 highly variable microsatellite polymorphisms in rhesus macaques (Macaca mulatta) selected for pedigree or population genetic analysis. | Rogers J et al. | β | 2005 | β |
| A population-based LD map of the human chromosome 6p. | Yu HX et al. | β | 2005 | β |
| A variance component analysis on recombination rate in the COGA pedigrees. | Wang L et al. | β | 2005 | β |
| Breakpoints of variant 9;22 translocations in chronic myeloid leukemia locate preferentially in the CG-richest regions of the genome. | Fisher AM et al. | β | 2005 | β |
| Calibrating a coalescent simulation of human genome sequence variation. | Schaffner SF et al. | β | 2005 | β |
| Chromosomal rearrangements are associated with higher rates of molecular evolution in mammals. | Marques-Bonet T et al. | β | 2005 | β |
| Combined linkage and association mapping of quantitative trait loci by multiple markers. | Jung J et al. | β | 2005 | β |
| Comparison of marker types and map assumptions using Markov chain Monte Carlo-based linkage analysis of COGA data. | Sieh W et al. | β | 2005 | β |
| Corroboration of a familial chordoma locus on chromosome 7q and evidence of genetic heterogeneity using single nucleotide polymorphisms (SNPs). | Yang X' et al. | β | 2005 | β |
| Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14. | Edenberg HJ et al. | β | 2005 | β |
| Description of the International Consortium For Prostate Cancer Genetics, and failure to replicate linkage of hereditary prostate cancer to 20q13. | Schaid DJ et al. | β | 2005 | β |
| Disentangling linkage disequilibrium and linkage from dense single-nucleotide polymorphism trio data. | Clarke GM et al. | β | 2005 | β |
| DNA sequence and analysis of human chromosome 18. | Nusbaum C et al. | β | 2005 | β |
| Evaluation of linkage disequilibrium and its effect on non-parametric multipoint linkage analysis using two high density single-nucleotide polymorphism mapping panels. | Murray SS | β | 2005 | β |
| Evidence for clinical and genetic heterogeneity of syndactyly type I: the phenotype of second and third toe syndactyly maps to chromosome 3p21.31. | Malik S et al. | β | 2005 | β |
| Fine mapping of autosomal dominant nonsyndromic hearing impairment DFNA21 to chromosome 6p24.1-22.3. | de Brouwer AP et al. | β | 2005 | β |
| Fine-scale recombination patterns differ between chimpanzees and humans. | Ptak SE et al. | β | 2005 | β |
| Fitting background-selection predictions to levels of nucleotide variation and divergence along the human autosomes. | Reed FA et al. | β | 2005 | β |
| Generation and annotation of the DNA sequences of human chromosomes 2 and 4. | Hillier LW et al. | β | 2005 | β |
| Genetic association studies of complex traits: design and analysis issues. | Newton-Cheh C et al. | β | 2005 | β |
| Genetics of psoriasis in Iceland: evidence for linkage of subphenotypes to distinct Loci. | Karason A et al. | β | 2005 | β |
| Genetic time-series analysis identifies a major QTL for in vivo alcohol metabolism not predicted by in vitro studies of structural protein polymorphism at the ADH1B or ADH1C loci. | Birley AJ et al. | β | 2005 | β |
| Genetic variability in a genomic region with long-range linkage disequilibrium reveals traces of a bottleneck in the history of the European population. | Schmegner C et al. | β | 2005 | β |
| Genome-wide analysis of the frequency and distribution of crossovers at male and female meiosis in Sinapis alba L. (white mustard). | Nelson MN et al. | β | 2005 | β |
| Genome-wide identity-by-descent sharing among CEPH siblings. | Gagnon A et al. | β | 2005 | β |
| Genome-wide linkage analyses of extended Utah pedigrees identifies loci that influence recurrent, early-onset major depression and anxiety disorders. | Camp NJ et al. | β | 2005 | β |
| Genome-wide linkage analysis for alcohol dependence: a comparison between single-nucleotide polymorphism and microsatellite marker assays. | Ma Q et al. | β | 2005 | β |
| Genome-wide linkage disequilibrium from 100,000 SNPs in the East Finland founder population. | Uimari P et al. | β | 2005 | β |
| Genomic regions exhibiting positive selection identified from dense genotype data. | Carlson CS et al. | β | 2005 | β |
| Haplotype tagging efficiency in worldwide populations in CTLA4 gene. | RamΓrez-Soriano A et al. | β | 2005 | β |
| Hotspots of mutation and breakage in dog and human chromosomes. | Webber C et al. | β | 2005 | β |
| How homologous recombination generates a mutable genome. | Hurles M | β | 2005 | β |
| Human recombination hot spots hidden in regions of strong marker association. | Jeffreys AJ et al. | β | 2005 | β |
| Identifying nineteenth century genealogical links from genotypes. | Stankovich J et al. | β | 2005 | β |
| Increased level of linkage disequilibrium in rural compared with urban communities: a factor to consider in association-study design. | Vitart V et al. | β | 2005 | β |
| Initial sequence of the chimpanzee genome and comparison with the human genome. | Chimpanzee Sequencing and Analysis Consortium | β | 2005 | β |
| In silico analysis of disease-association mapping strategies using the coalescent process and incorporating ascertainment and selection. | Wang Y et al. | β | 2005 | β |
| Interrogating multiple aspects of variation in a full resequencing data set to infer human population size changes. | Voight BF et al. | β | 2005 | β |
| Large-scale recombination rate patterns are conserved among human populations. | Serre D et al. | β | 2005 | β |
| Linkage analysis of a completely ascertained sample of familial schizophrenics and bipolars from Palau, Micronesia. | Klei L et al. | β | 2005 | β |
| Linkage mapping reveals sex-dimorphic map distances in a passerine bird. | Hansson B et al. | β | 2005 | β |
| Linkage of ischemic stroke to the PDE4D region on 5q in a Swedish population. | Nilsson-Ardnor S et al. | β | 2005 | β |
| Microcephalin, a gene regulating brain size, continues to evolve adaptively in humans. | Evans PD et al. | β | 2005 | β |
| Microsatellite variation and evolution of human lactase persistence. | Coelho M et al. | β | 2005 | β |
| PINK1, Parkin, and DJ-1 mutations in Italian patients with early-onset parkinsonism. | Klein C et al. | β | 2005 | β |
| Recombination and speciation. | Butlin RK | β | 2005 | β |
| Recombination difference between sexes: a role for haploid selection. | Lenormand T et al. | β | 2005 | β |
| Recombination hotspots and population structure in Plasmodium falciparum. | Mu J et al. | β | 2005 | β |
| RECORD: a novel method for ordering loci on a genetic linkage map. | Van Os H et al. | β | 2005 | β |
| Sequence features in regions of weak and strong linkage disequilibrium. | Smith AV et al. | β | 2005 | β |
| Sex-linked recombination variation and distribution of disease-related genes. | Chelala C et al. | β | 2005 | β |
| Sex, not genotype, determines recombination levels in mice. | Lynn A et al. | β | 2005 | β |
| Sibship T2 association tests of complex diseases for tightly linked markers. | Fan R et al. | β | 2005 | β |
| SimPed: a simulation program to generate haplotype and genotype data for pedigree structures. | Leal SM et al. | β | 2005 | β |
| SNP microarray analysis for genome-wide detection of crossover regions. | Wirtenberger M et al. | β | 2005 | β |
| Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome browser. | Stenger JE et al. | β | 2005 | β |
| Substantial regional variation in substitution rates in the human genome: importance of GC content, gene density, and telomere-specific effects. | Arndt PF et al. | β | 2005 | β |
| The case for selection at CCR5-Delta32. | Sabeti PC et al. | β | 2005 | β |
| The DNA sequence of the human X chromosome. | Ross MT et al. | β | 2005 | β |
| The effect of genetic drift in a young genetically isolated population. | Pardo LM et al. | β | 2005 | β |
| The extent of linkage disequilibrium caused by selection on G6PD in humans. | Saunders MA et al. | β | 2005 | β |
| The importance of modelling heterogeneity in complex disease: application to NIMH Schizophrenia Genetics Initiative data. | Holliday E et al. | β | 2005 | β |
| The linkage disequilibrium maps of three human chromosomes across four populations reflect their demographic history and a common underlying recombination pattern. | De La Vega FM et al. | β | 2005 | β |
| The scale of mutational variation in the murid genome. | Gaffney DJ et al. | β | 2005 | β |
| The telomere of human chromosome 1p contains at least two independent autosomal dominant congenital cataract genes. | McKay JD et al. | β | 2005 | β |
| Use of the genomic matching technique to complement multiplex STR profiling reduces DNA profiling costs in high volume crimes and intelligence led screens. | Laird R et al. | β | 2005 | β |
| Whole-genome association analysis to identify markers associated with recombination rates using single-nucleotide polymorphisms and microsatellites. | Huang S et al. | β | 2005 | β |
| Whole genomewide linkage screen for neural tube defects reveals regions of interest on chromosomes 7 and 10. | Rampersaud E et al. | β | 2005 | β |
| Why are young and old repetitive elements distributed differently in the human genome? | Belle EM et al. | β | 2005 | β |
| Why do human diversity levels vary at a megabase scale? | Hellmann I et al. | β | 2005 | β |