Early experience and the development of stress reactivity and regulation in children.
paper
Cited
Public
- Authors
- Loman, Michelle M; Gunnar, Megan R; Early Experience, Stress, and Neurobehavioral Development Center
- Year
- 2010
- Journal
- Neuroscience and biobehavioral reviews
- PMID
- 19481109
- DOI
- 10.1016/j.neubiorev.2009.05.007
- PMCID
- PMC2848877
Children who spend early portions of their lives in institutions or those maltreated in their families of origin are at risk for developing emotional and behavioral problems reflecting disorders of emotion and attention regulation. Animal models may help explicate the mechanisms producing these effects. Despite the value of the animal models, many questions remain in using the animal data to guide studies of human development. In 1999, the National Institute of Mental Health in the United States funded a research network to address unresolved issues and enhance translation of basic animal early experience research to application in child research. Professor Seymour Levine was both the inspiration for and an active member of this research network until his death in October of 2007. This review pays tribute to his legacy by outlining the conceptual model which is now guiding our research studies.
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| Title | Year | PMID |
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| Gene-environment interaction in psychological traits and disorders. | 2011 | 21219196 |
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| In my end is my beginning: developmental trajectories of adverse childhood experiences to late-life suicide. | Sachs-Ericsson NJ et al. | — | 2016 | → |
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| Maternal sensitivity buffers the adrenocortical implications of intimate partner violence exposure during early childhood. | Hibel LC et al. | — | 2011 | → |
| Postnatal serotonin type 2 receptor blockade prevents the emergence of anxiety behavior, dysregulated stress-induced immediate early gene responses, and specific transcriptional changes that arise following early life stress. | Benekareddy M et al. | — | 2011 | → |
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