A systematic method for clinical description and classification of personality variants. A proposal.
- Authors
- Cloninger, C R
- Year
- 1987
- Journal
- Archives of general psychiatry
- PMID
- 3579504
- DOI
- 10.1001/archpsyc.1987.01800180093014
A systematic method for clinical description and classification of both normal and abnormal personality variants is proposed based on a general biosocial theory of personality. Three dimensions of personality are defined in terms of the basic stimulus-response characteristics of novelty seeking, harm avoidance, and reward dependence. The possible underlying genetic and neuroanatomical bases of observed variation in these dimensions are reviewed and considered in relation to adaptive responses to environmental challenge. The functional interaction of these dimensions leads to integrated patterns of differential response to novelty, punishment, and reward. The possible tridimensional combinations of extreme (high or low) variants on these basic stimulus-response characteristics correspond closely to traditional descriptions of personality disorders. This reconciles dimensional and categorical approaches to personality description. It also implies that the underlying structure of normal adaptive traits is the same as that of maladaptive personality traits, except for schizotypal and paranoid disorders.
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| Rats selectively bred for showing divergent behavioral traits in response to stress or novelty or spontaneous yawning with a divergent frequency show similar changes in sexual behavior: the role of dopamine. | Melis MR et al. | β | 2019 | β |
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| The Comparison of Psychological Characteristics between Korean and Japanese Women Pro-Basketball Players. | Ha EJ et al. | β | 2019 | β |
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| A computer-based avatar task designed to assess behavioral inhibition extends to behavioral avoidance but not cognitive avoidance. | Allen MT | β | 2018 | β |
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| Are Personality Characteristics as Measured by the Temperament and Character Inventory (TCI) Associated with Obesity Treatment Outcomes? A Systematic Review. | Dalle Grave R et al. | β | 2018 | β |
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| Cerebellar BDNF Promotes Exploration and Seeking for Novelty. | Laricchiuta D et al. | β | 2018 | β |
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| Do Event-Related Evoked Potentials Reflect Apathy Tendency and Motivation? | Takayoshi H et al. | β | 2018 | β |
| Effects of Amphetamine on Sensorimotor Gating and Neurocognition in Antipsychotic-Medicated Schizophrenia Patients. | Swerdlow NR et al. | β | 2018 | β |
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| Fitting motivational content and process: A systematic investigation of fit between value framing and self-regulation. | Woltin KA et al. | β | 2018 | β |
| Food and nutrient intakes by temperament traits: findings in the Helsinki Birth Cohort Study. | PerΓ€lΓ€ MM et al. | β | 2018 | β |
| GAD65 Promoter Polymorphism rs2236418 Modulates Harm Avoidance in Women via Inhibition/Excitation Balance in the Rostral ACC. | Colic L et al. | β | 2018 | β |
| Gray Matter Volume of a Region in the Thalamic Pulvinar Is Specifically Associated with Novelty Seeking. | Stam D et al. | β | 2018 | β |
| Influence of Personality Traits on the Severity of Alcohol Use Disorders. | Γlvarez A et al. | β | 2018 | β |
| Major and minor life events, personality and psychopathology in children with tourette syndrome. | Horesh N et al. | β | 2018 | β |
| Modulation of locus coeruleus activity by novel oddball stimuli. | Krebs RM et al. | β | 2018 | β |
| Personality as an intermediate phenotype for genetic dissection of alcohol use disorder. | Oreland L et al. | β | 2018 | β |
| Possible associations of personality traits representing harm avoidance and self-directedness with medication adherence in Japanese patients with type 2 diabetes. | Tominaga Y et al. | β | 2018 | β |
| Psychological Symptoms in Late Adolescence and Long-Term Risk of Suicide and Suicide Attempt. | Hogstedt C et al. | β | 2018 | β |
| Risk profiles of personality traits for suicidality among mood disorder patients and community controls. | Su MH et al. | β | 2018 | β |
| Self-Transcendence in Mountaineering and BASE Jumping. | Monasterio E et al. | β | 2018 | β |
| Temperament clusters associate with anxiety disorder comorbidity in depression. | Paavonen V et al. | β | 2018 | β |
| The association between COMT rs4680 and 5-HTTLPR genotypes and concussion history in South African rugby union players. | Mc Fie S et al. | β | 2018 | β |
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| The Parkinsonian Personality: More Than Just a "Trait". | Luca A et al. | β | 2018 | β |
| The relationship between emotion regulation strategies, personality traits and skin picking behaviours in a non-clinical sample of Polish adults. | Prochwicz K et al. | β | 2018 | β |
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| The salience network and human personality: Integrity of white matter tracts within anterior and posterior salience network relates to the self-directedness character trait. | Prillwitz CC et al. | β | 2018 | β |
| Ventral striatal dopamine transporter availability is associated with lower trait motor impulsivity in healthy adults. | Smith CT et al. | β | 2018 | β |
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| An integrative study of motivation and goal regulation processes in subclinical anxiety, depression and hypomania. | Dickson JM et al. | β | 2017 | β |
| Avoiding boredom: Caudate and insula activity reflects boredom-elicited purchase bias. | Dal Mas DE et al. | β | 2017 | β |
| Beyond Behavioral Inhibition: A Computer Avatar Task Designed to Assess Behavioral Inhibition Extends to Harm Avoidance. | Allen MT et al. | β | 2017 | β |
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| Differential housing and novelty response: Protection and risk from locomotor sensitization. | Garcia EJ et al. | β | 2017 | β |
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| Explicit and Implicit Approach vs. Avoidance Tendencies towards High vs. Low Calorie Food Cues in Patients with Obesity and Active Binge Eating Disorder. | Paslakis G et al. | β | 2017 | β |
| Exploring the relationship between social attachment and dopamine D<sub>2/3</sub> receptor availability in the brains of healthy humans using [<sup>11</sup>C]-(+)-PHNO. | Caravaggio F et al. | β | 2017 | β |
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| Neural correlates of altered feedback learning in women recovered from anorexia nervosa. | Ritschel F et al. | β | 2017 | β |
| No Association between the Polymorphism rs6943555 in the <i>AUTS2</i> Gene and Personality Traits in Japanese University Students. | Narita S et al. | β | 2017 | β |
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| Personality in Parkinson's disease: Clinical, behavioural and cognitive correlates. | Santangelo G et al. | β | 2017 | β |
| PERSONALITY TRAITS, ANGER AND PSYCHIATRIC SYMPTOMS RELATED TO QUALITY OF LIFE IN PATIENTS WITH NEWLY DIAGNOSED DIGESTIVE SYSTEM CANCER. | Honorato NP et al. | β | 2017 | β |
| Preliminary evidence for a role of the personality trait in visual perceptual learning. | Zhang M et al. | β | 2017 | β |
| Psychopathological, temperamental, and characteristic factors in adults with remaining childhood attention-deficit hyperactivity symptoms. | Kim KM et al. | β | 2017 | β |
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| Sensation seeking and impulsive traits as personality endophenotypes for antisocial behavior: Evidence from two independent samples. | Mann FD et al. | β | 2017 | β |
| Similarities and Differences in Psychology. | Chen Y et al. | β | 2017 | β |
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| The effects of temperament and character traits on perceived social support and quality of life in patients with epilepsy. | Demirci K et al. | β | 2017 | β |
| The influence of personality traits and emotional and behavioral problems on repetitive nonsuicidal self-injury in a school sample. | LΓΌdtke J et al. | β | 2017 | β |
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| Ventral striatum and amygdala activity as convergence sites for early adversity and conduct disorder. | Holz NE et al. | β | 2017 | β |
| Viewing the Personality Traits Through a Cerebellar Lens: a Focus on the Constructs of Novelty Seeking, Harm Avoidance, and Alexithymia. | Petrosini L et al. | β | 2017 | β |
| A Functional 3'UTR Polymorphism (rs2235749) of Prodynorphin Alters microRNA-365 Binding in Ventral Striatonigral Neurons to Influence Novelty Seeking and Positive Reward Traits. | Egervari G et al. | β | 2016 | β |
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| Behavioral measures of risk tasking, sensation seeking and sensitivity to reward may reflect different motivations for spicy food liking and consumption. | Byrnes NK et al. | β | 2016 | β |
| Cognitive Dysfunction, Affective States, and Vulnerability to Nicotine Addiction: A Multifactorial Perspective. | Besson M et al. | β | 2016 | β |
| Cognitive, Emotional, Temperament, and Personality Trait Correlates of Suicidal Behavior. | Giner L et al. | β | 2016 | β |
| Comparison of the Temperament and Character of Patients Referred to Cosmetic Nasal Surgeon in Shiraz Hospitals, 2015. | Sharif F et al. | β | 2016 | β |
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| Dimensions of Compulsive Exercise across Eating Disorder Diagnostic Subtypes and the Validation of the Spanish Version of the Compulsive Exercise Test. | Sauchelli S et al. | β | 2016 | β |
| Disadvantage of Social Sensitivity: Interaction of Oxytocin Receptor Genotype and Child Maltreatment on Brain Structure. | Dannlowski U et al. | β | 2016 | β |
| Discriminability of personality profiles in isolated and Co-morbid marijuana and nicotine users. | Ketcherside A et al. | β | 2016 | β |
| Effortful control as a dimension of temperament is negatively associated with prefrontal serotonin transporter availability in obese and non-obese individuals. | Zientek F et al. | β | 2016 | β |
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| Happier, faster: Developmental changes in the effects of mood and novelty on responses. | Schomaker J et al. | β | 2016 | β |
| Harm Avoidance and Self-Directedness Characterize Fibromyalgic Patients and the Symptom Severity. | Leombruni P et al. | β | 2016 | β |
| Hemispheric Lateralization of Resting-State Functional Connectivity of the Anterior Insula: Association with Age, Gender, and a Novelty-Seeking Trait. | Kann S et al. | β | 2016 | β |
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| Impulsivity is relevant for trauma exposure and PTSD symptoms in a non-clinical population. | Netto LR et al. | β | 2016 | β |
| Individual Differences in Cognitive Control Circuit Anatomy Link Sensation Seeking, Impulsivity, and Substance Use. | Holmes AJ et al. | β | 2016 | β |
| Individual variation in the neural processes of motor decisions in the stop signal task: the influence of novelty seeking and harm avoidance personality traits. | Hu J et al. | β | 2016 | β |
| Influence of the Novelty-Seeking Endophenotype on the Rewarding Effects of Psychostimulant Drugs in Animal Models. | Arenas MC et al. | β | 2016 | β |
| Lessons learned--resolving the enigma of genetic factors in IBS. | Gazouli M et al. | β | 2016 | β |
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| Personality in women with endometriosis: temperament and character dimensions and pelvic pain. | Facchin F et al. | β | 2016 | β |
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| Regional Cerebral Glucose Metabolism in Novelty Seeking and Antisocial Personality: A Positron Emission Tomography Study. | Park SH et al. | β | 2016 | β |
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| Relationship Between Temperament and Character Traits, Mood, and Medications in Bipolar I Disorder. | Chavez SB et al. | β | 2016 | β |
| Replication of the association between CHRNA4 rs1044396 and harm avoidance in a large population-based sample. | Bey K et al. | β | 2016 | β |
| Review of pharmacologic treatment in cluster A personality disorders. | Koch J et al. | β | 2016 | β |
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| Stress reactivity and personality in extreme sport athletes: The psychobiology of BASE jumpers. | Monasterio E et al. | β | 2016 | β |
| The association of Internet addiction symptoms with impulsiveness, loneliness, novelty seeking and behavioral inhibition system among adults with attention-deficit/hyperactivity disorder (ADHD). | Li W et al. | β | 2016 | β |
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| Analysis of Association between Norepinephrine Transporter Gene Polymorphisms and Personality Traits of NEO-FFI in a Japanese Population. | Narita S et al. | β | 2015 | β |
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| Brain Genomics Superstruct Project initial data release with structural, functional, and behavioral measures. | Holmes AJ et al. | β | 2015 | β |
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| Changes in the Temperament and Character Inventory dimensions after paroxetine treatment in patients with major depressive disorder. | Tomita T et al. | β | 2015 | β |
| Childhood Sexual Abuse and Impulsive Personality Traits: Mixed Evidence for Moderation by <i>DRD4</i> Genotype. | Harden KP et al. | β | 2015 | β |
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| Development and validation of triarchic psychopathy scales from the Multidimensional Personality Questionnaire. | Brislin SJ et al. | β | 2015 | β |
| Doubling Your Payoff: Winning Pain Relief Engages Endogenous Pain Inhibition | Becker S et al. | β | 2015 | β |
| Effect of refractive error on temperament and character properties. | Kalkan Akcay E et al. | β | 2015 | β |
| Facial transplantation in a blind patient: psychologic, marital, and family outcomes at 15 months follow-up. | Lemmens GM et al. | β | 2015 | β |
| Four broad temperament dimensions: description, convergent validation correlations, and comparison with the Big Five. | Fisher HE et al. | β | 2015 | β |
| Harmonic and frequency modulated ultrasonic vocalizations reveal differences in conditioned and unconditioned reward processing. | Garcia EJ et al. | β | 2015 | β |
| Impulsive alcohol-related risk-behavior and emotional dysregulation among individuals with a serotonin 2B receptor stop codon. | Tikkanen R et al. | β | 2015 | β |
| Impulsivity as a predictor of treatment outcome in substance use disorders: review and synthesis. | Loree AM et al. | β | 2015 | β |
| Increased Reward-Related Behaviors during Sleep and Wakefulness in Sleepwalking and Idiopathic Nightmares. | Perogamvros L et al. | β | 2015 | β |
| Individual differences in approach-avoidance aptitude: some clues from research on Parkinson's disease. | Costa A et al. | β | 2015 | β |
| Individualized relapse prediction: Personality measures and striatal and insular activity during reward-processing robustly predict relapse. | Gowin JL et al. | β | 2015 | β |
| International Adaptations of the Millon Clinical Multiaxial Inventory: Construct Validity and Clinical Applications. | Rossi G et al. | β | 2015 | β |
| Is dependent personality disorder associated with mild cognitive impairment and dementia in Central Africa? A result from the EPIDEMCA programme. | Pilleron S et al. | β | 2015 | β |
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| Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder. | Genetics of Personality Consortium et al. | β | 2015 | β |
| Might the temperament be a bias in clinical study on attention-deficit hyperactivity disorder (ADHD)?: Novelty Seeking dimension as a core feature of ADHD. | Donfrancesco R et al. | β | 2015 | β |
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| Neuroanatomical correlates of negative emotionality-related traits: A systematic review and meta-analysis. | Mincic AM | β | 2015 | β |
| New evidence of heterogeneity in social anxiety disorder: defining two qualitatively different personality profiles taking into account clinical, environmental and genetic factors. | Binelli C et al. | β | 2015 | β |
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| Personality construct of Sasang Personality Questionnaire in an adolescent sample. | Chae H et al. | β | 2015 | β |
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| Personality in remitted major depressive disorder with single and recurrent episodes assessed with the Temperament and Character Inventory. | Teraishi T et al. | β | 2015 | β |
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| Person-centered osteopathic practice: patients' personality (body, mind, and soul) and health (ill-being and well-being). | Fahlgren E et al. | β | 2015 | β |
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| Psychometric Evaluation of the Substance Use Risk Profile Scale (SURPS) in an Inpatient Sample of Substance Users Using Cue-Reactivity Methodology. | Schlauch RC et al. | β | 2015 | β |
| Psychopathy and Low Anxiety: Meta-Analytic Evidence for the Absence of Inhibition, Not Affect. | Derefinko KJ | β | 2015 | β |
| Relationship between temperament, character and the autistic trait in parents of children with autistic spectrum disorder. | Kadak MT et al. | β | 2015 | β |
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| Serotonergic Systems in the Pathophysiology of Ethanol Dependence: Relevance to Clinical Alcoholism. | Marcinkiewcz CA | β | 2015 | β |
| Some personality traits converge gradually by long-term partnership through the lifecourse--genetic and environmental structure of Cloninger's temperament and character dimensions. | Yang S et al. | β | 2015 | β |
| Standardization and normative data of the Greek version of the temperament and character inventory (TCI). | Fountoulakis KN et al. | β | 2015 | β |
| Study on the Difference of BIS/BAS Scale between Sasang Types. | Lee SJ et al. | β | 2015 | β |
| Temperamental and character profiles of preschool children with ODD, ADHD, and anxiety disorders. | Melegari MG et al. | β | 2015 | β |
| Temperamental Predictive Factors for Success in Korean Professional Baseball Players. | Kang KD et al. | β | 2015 | β |
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| Temperament and character dimensions assessed in general population, in individuals with psychoactive substance dependence and in young male conscripts. | Vitoratou S et al. | β | 2015 | β |
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