Early family environment, current adversity, the serotonin transporter promoter polymorphism, and depressive symptomatology.
paper
Cited
Public
Unavailable
- Authors
- Taylor, Shelley E; Way, Baldwin M; Welch, William T; Hilmert, Clayton J; Lehman, Barbara J; Eisenberger, Naomi I
- Year
- 2006
- Journal
- Biological psychiatry
- PMID
- 16934775
- DOI
- 10.1016/j.biopsych.2006.04.019
BACKGROUND: Mixed evidence has suggested that homozygous carriers of the short allele (s/s) of the serotonin transporter gene-linked polymorphic region (5-HTTLPR) may be at increased risk for depression, if they have also been exposed to early or current adversity/stress. We address this debate by examining the relation of a stressful early family environment, recent adversity/stress, and the 5-HTTLPR to depressive symptomatology in a normal sample. METHODS: A nonclinical sample of 118 young adult men and women completed assessments of early family environment, recent stressful events, psychosocial resources, and psychological distress, including depressive symptomatology. The 5-HTTLPR was genotyped using a standard protocol with DNA extracted from oral fluid. RESULTS: A stressful early family environment was significantly related to depressive symptomatology. In addition, gene-by-environment (GxE) interactions were observed between the 5-HTTLPR and both early family environment and current adversity/stress. Individuals homozygous for the short allele had greater depressive symptomatology if they had experienced early or recent adversity but significantly less depressive symptomatology if they reported a supportive early environment or recent positive experiences, compared with participants with the s/l or l/l genotype. CONCLUSIONS: Early or current environment, in conjunction with the serotonin transporter polymorphism, predicts depressive symptomatology.
No figures extracted from this document.
No chunks β full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Early childhood stress and amygdala structure in children and adolescents with neurodevelopmental disorders. | Kuenzel E et al. | β | 2025 | β |
| Efficacy and safety of electroacupuncture for post-stroke depression: a systematic review and meta-analysis. | Liang Y et al. | β | 2025 | β |
| Religiosity: A resilience factor protecting against depression in medical interns. | Kriebel AR et al. | β | 2025 | β |
| Risky family environment, white matter organization, and effective parenting in expectant fathers. | CΓ‘rdenas SI et al. | β | 2025 | β |
| Brain network integration underpins differential susceptibility of adolescent anxiety. | Ding Q et al. | β | 2024 | β |
| Childhood Adversity and Engagement in Adulthood: The Role of Attachment as a Mediator. | Aquilina S et al. | β | 2024 | β |
| The role of environmental sensitivity in the mental health of Syrian refugee children: a multi-level analysis. | May AK et al. | β | 2024 | β |
| Do childhood adversity and sensory processing sensitivity interact to predict meaningful activity engagement in adulthood? | Kerley L et al. | β | 2023 | β |
| First Onset in Adulthood of Mental Disorders: Exposure to War <i>vs</i>. Non-war Childhood Adversities: A National Study. | Karam E et al. | β | 2023 | β |
| Prenatal serotonin reuptake inhibitor antidepressant exposure, SLC6A4 genetic variations, and cortisol activity in 6-year-old children of depressed mothers: A cohort study. | Zusman EZ et al. | β | 2023 | β |
| Use of mobile technology to identify behavioral mechanisms linked to mental health outcomes in Kenya: protocol for development and validation of a predictive model. | Njoroge W et al. | β | 2023 | β |
| Early-life interparental relationship quality and late-life depressive symptoms: A mediation analysis. | Zhao X et al. | β | 2022 | β |
| Emotional self-regulation, impulsivity, 5-HTTLPR and tobacco use behavior among psychiatric inpatients. | Wilkinson AV et al. | β | 2022 | β |
| Parenting and the Serotonin Transporter Gene (5HTTLPR), Is There an Association? A Systematic Review of the Literature. | Landoni M et al. | β | 2022 | β |
| Prevalence and risk factors for depression among training physicians in China and the United States. | Chen L et al. | β | 2022 | β |
| Quo Vadis Psychiatry? Why It Is Time to Endorse Evolutionary Theory. | BrΓΌne M et al. | β | 2022 | β |
| Rethinking minority stress: A social safety perspective on the health effects of stigma in sexually-diverse and gender-diverse populations. | Diamond LM et al. | β | 2022 | β |
| Risky Early Family Environment and Genetic Associations with Adult Metabolic Dysregulation. | Huizar YP et al. | β | 2022 | β |
| The relationship of maternal rank, 5-HTTLPR genotype, and MAOA-LPR genotype to temperament in infant rhesus monkeys (Macaca mulatta). | Capitanio JP et al. | β | 2022 | β |
| Three phases of Gene Γ Environment interaction research: Theoretical assumptions underlying gene selection. | Zhang X et al. | β | 2022 | β |
| Trends in Depressive Symptoms and Associated Factors During Residency, 2007 to 2019 : A Repeated Annual Cohort Study. | Fang Y et al. | β | 2022 | β |
| Dopamine D4 receptor gene polymorphism (DRD4 VNTR) moderates real-world behavioural response to the food retail environment in children. | Paquet C et al. | β | 2021 | β |
| Molecular impacts of childhood abuse on the human brain. | Ibrahim P et al. | β | 2021 | β |
| Prediction of suicidal ideation risk in a prospective cohort study of medical interns. | Malone TL et al. | β | 2021 | β |
| Prevalence of Exposure to Complex Trauma and Community Violence and Their Associations With Internalizing and Externalizing Symptoms. | Yearwood K et al. | β | 2021 | β |
| Serotonergic sensitivity alleles moderate relations between attachment security at age three and socioemotional competence at age five. | Lee JK et al. | β | 2021 | β |
| The peril and promise of sensitivity in eating disorders. | Sim L et al. | β | 2021 | β |
| The Youth and Childhood Adversity Scale: a step towards developing a new measure of adversity and its severity. | Schlechter P et al. | β | 2021 | β |
| A Model of Aggressive Behavior: Early Adversity, Impulsivity, and Response Inhibition. | Madole JW et al. | β | 2020 | β |
| Does 5-HTTLPR moderate the effect of the quality of environmental context on maternal sensitivity? Testing the differential susceptibility hypothesis. | BaiΓ£o R et al. | β | 2020 | β |
| Genomic prediction of depression risk and resilience under stress. | Fang Y et al. | β | 2020 | β |
| Oxytocin Receptor Gene (OXTR) and Childhood Adversity Influence Trust. | Zheng S et al. | β | 2020 | β |
| Victimization, Poverty, and Resilience Resources: Stress Process Considerations for Adolescent Mental Health. | Nurius P et al. | β | 2020 | β |
| A biocultural approach to psychiatric illnesses. | Shattuck EC | β | 2019 | β |
| Childhood trauma in mood disorders: Neurobiological mechanisms and implications for treatment. | Jaworska-Andryszewska P et al. | β | 2019 | β |
| Child maltreatment and psychosis. | Kaufman J et al. | β | 2019 | β |
| Genomic Prediction of Depression Risk and Resilience Under Stress | Fang Y et al. | β | 2019 | β |
| Predicting Behavior Problems in Korean Preschoolers: Interactions of the <i>SLC6A4</i> Gene and Maternal Negative Affectivity. | Ha J et al. | β | 2019 | β |
| Residency Program Factors Associated With Depressive Symptoms in Internal Medicine Interns: A Prospective Cohort Study. | Pereira-Lima K et al. | β | 2019 | β |
| The nature and nurture of social development: The role of 5-HTTLPR and gene-parenting interactions. | Caplan B et al. | β | 2019 | β |
| Effect of socioeconomic status on behavioral problems from preschool to early elementary school - A Japanese longitudinal study. | Hosokawa R et al. | β | 2018 | β |
| Gene Γ Environment Interaction in Developmental Disorders: Where Do We Stand and What's Next? | Esposito G et al. | β | 2018 | β |
| Gene-environment interactions between stress and 5-HTTLPR in depression: A meta-analytic update. | Bleys D et al. | β | 2018 | β |
| Self-compassion: An adaptive link between early memories and women's quality of life. | Marta-SimΓ΅es J et al. | β | 2018 | β |
| Age is no barrier: predictors of academic success in older learners. | Imlach AR et al. | β | 2017 | β |
| Association between salivary serotonin and the social sharing of happiness. | Matsunaga M et al. | β | 2017 | β |
| Association between the serotonin transporter gene polymorphism and verbal learning in older adults is moderated by gender. | Imlach AR et al. | β | 2017 | β |
| Behavioral Genetics in Criminal and Civil Courts. | Sabatello M et al. | β | 2017 | β |
| Beyond risk: Prospective effects of GABA Receptor Subunit Alpha-2 (GABRA2) Γ Positive Peer Involvement on adolescent behavior. | Trucco EM et al. | β | 2017 | β |
| Childhood quality influences genetic sensitivity to environmental influences across adulthood: A life-course Gene Γ Environment interaction study. | Keers R et al. | β | 2017 | β |
| Cumulative prenatal exposure to adversity reveals associations with a broad range of neurodevelopmental outcomes that are moderated by a novel, biologically informed polygenetic score based on the serotonin transporter solute carrier family C6, member 4 (SLC6A4) gene expression. | Silveira PP et al. | β | 2017 | β |
| Developmental changes in serotonin signaling: Implications for early brain function, behavior and adaptation. | Brummelte S et al. | β | 2017 | β |
| Early Pubertal Timing and Childhood Family Adversity Interact to Predict Newlywed Women's Anxiety Symptoms. | Winer JP et al. | β | 2017 | β |
| Effects of bonding with parents and home culture on intercultural adaptations and the moderating role of genes. | Phua DY et al. | β | 2017 | β |
| Epigenetic and Neural Circuitry Landscape of Psychotherapeutic Interventions. | Miller CWT | β | 2017 | β |
| Extremely low birth weight babies grown up: Gene-environment interaction predicts internalizing problems in the third and fourth decades of life. | Lahat A et al. | β | 2017 | β |
| Gene and environment interaction: Is the differential susceptibility hypothesis relevant for obesity? | Dalle Molle R et al. | β | 2017 | β |
| Gene Γ Environment Interactions: From Molecular Mechanisms to Behavior. | Halldorsdottir T et al. | β | 2017 | β |
| Immune System Activation and Depression: Roles of Serotonin in the Central Nervous System and Periphery. | Robson MJ et al. | β | 2017 | β |
| Parenting and adolescents' psychological adjustment: Longitudinal moderation by adolescents' genetic sensitivity. | Stocker CM et al. | β | 2017 | β |
| Paroxetine versus Venlafaxine and Escitalopram in Korean Patients with Major Depressive Disorder: A Randomized, Rater-blinded, Six-week Study. | Woo YS et al. | β | 2017 | β |
| Plastic and immobile: Unequal intergenerational mobility by genetic sensitivity score within sibling pairs. | Rauscher E | β | 2017 | β |
| Prior fear conditioning does not impede enhanced active avoidance in serotonin transporter knockout rats. | Schipper P et al. | β | 2017 | β |
| Protective Processes Underlying the Links between Marital Quality and Physical Health. | Slatcher RB et al. | β | 2017 | β |
| Relationships Between Self-Reported and Observed Parenting Behaviour, Adolescent Disordered Eating Attitudes and Behaviours, and the 5-HTTLPR Polymorphism: Data From the Australian Temperament Project. | Rozenblat V et al. | β | 2017 | β |
| Serotonin transporter gene (SLC6A4) polymorphism and susceptibility to a home-visiting maternal-infant attachment intervention delivered by community health workers in South Africa: Reanalysis of a randomized controlled trial. | Morgan B et al. | β | 2017 | β |
| A Genome-Wide Test of the Differential Susceptibility Hypothesis Reveals a Genetic Predictor of Differential Response to Psychological Treatments for Child Anxiety Disorders. | Keers R et al. | β | 2016 | β |
| Animal Models of Maternal Immune Activation in Depression Research. | Ronovsky M et al. | β | 2016 | β |
| Connections Matter: Social Networks and Lifespan Health in Primate Translational Models. | McCowan B et al. | β | 2016 | β |
| Differential sensitivity to the environment: contribution of cognitive biases and genes to psychological wellbeing. | Fox E et al. | β | 2016 | β |
| Differential Susceptibility of the Developing Brain to Contextual Adversity and Stress. | Boyce WT | β | 2016 | β |
| Early Childhood Adversity and its Associations With Anxiety, Depression, and Distress in Women With Breast Cancer. | McFarland DC et al. | β | 2016 | β |
| Effects of Recent Stress and Variation in the Serotonin Transporter Polymorphism (5-HTTLPR) on Depressive Symptoms: A Repeated-Measures Study of Adults Age 50 and Older. | Arpawong TE et al. | β | 2016 | β |
| Epigenetic marks as the link between environment and development: examination of the associations between attachment, socioeconomic status, and methylation of the SLC6A4 gene. | Jones-Mason K et al. | β | 2016 | β |
| Genetics as a molecular window into recovery, its treatment, and stress responses after stroke. | Juth V et al. | β | 2016 | β |
| Intergenerational Transmission of Stress in Humans. | Bowers ME et al. | β | 2016 | β |
| Mu opioid receptor polymorphism, early social adversity, and social traits. | Carver CS et al. | β | 2016 | β |
| Neural correlates of reflection on actual versus ideal self-discrepancy. | Shi Z et al. | β | 2016 | β |
| Non-replication of the association between 5HTTLPR and response to psychological therapy for child anxiety disorders. | Lester KJ et al. | β | 2016 | β |
| On the role of oxytocin in borderline personality disorder. | BrΓΌne M | β | 2016 | β |
| Stressing over anxiety: A novel interaction of 5-HTTPLR genotype and anxiety-related phenotypes in older adults. | Fogelman N et al. | β | 2016 | β |
| Understanding the impact of 5-HTTLPR, antidepressants, and acute tryptophan depletion on brain activation during facial emotion processing: A review of the imaging literature. | Raab K et al. | β | 2016 | β |
| A genetic analysis of the validity of the Hypomanic Personality Scale. | Johnson SL et al. | β | 2015 | β |
| Caregiving and 5-HTTLPR Genotype Predict Adolescent Physiological Stress Reactivity: Confirmatory Tests of GeneΒ ΓΒ Environment Interactions. | Sumner JA et al. | β | 2015 | β |
| Influence of life stress, 5-HTTLPR genotype, and SLC6A4 methylation on gene expression and stress response in healthy Caucasian males. | Duman EA et al. | β | 2015 | β |
| Life course pathways of adverse childhood experiences toward adult psychological well-being: A stress process analysis. | Nurius PS et al. | β | 2015 | β |
| Over-the-Counter Relief From Pains and Pleasures Alike: Acetaminophen Blunts Evaluation Sensitivity to Both Negative and Positive Stimuli. | Durso GR et al. | β | 2015 | β |
| Psychological distress following marital separation interacts with a polymorphism in the serotonin transporter gene to predict cardiac vagal control in the laboratory. | Hasselmo K et al. | β | 2015 | β |
| Sensory-processing sensitivity moderates the association between childhood experiences and adult life satisfaction. | Booth C et al. | β | 2015 | β |
| Short alleles, bigger smiles? The effect of 5-HTTLPR on positive emotional expressions. | Haase CM et al. | β | 2015 | β |
| Social support and the serotonin transporter genotype (5-HTTLPR) moderate levels of resilience, sense of coherence, and depression. | Reinelt E et al. | β | 2015 | β |
| Take your mind off it: Coping style, serotonin transporter linked polymorphic region genotype (5-HTTLPR), and children's internalizing and externalizing problems. | Cline JI et al. | β | 2015 | β |
| Variations in central serotonergic activity - relevance of the 5-HTTLPR, life events and their interaction. | Wielpuetz C et al. | β | 2015 | β |
| Web-Based Cognitive Behavioral Therapy Intervention for the Prevention of Suicidal Ideation in Medical Interns: A Randomized Clinical Trial. | Guille C et al. | β | 2015 | β |
| 5-HTTLPR polymorphism modulates neural mechanisms of negative self-reflection. | Ma Y et al. | β | 2014 | β |
| Adulthood personality correlates of childhood adversity. | Carver CS et al. | β | 2014 | β |
| An update on the interaction between the serotonin transporter promoter variant (5-HTTLPR), stress and depression, plus an exploration of non-confirming findings. | Sharpley CF et al. | β | 2014 | β |
| Commentary: beyond stressful life events and depression? --reflections on Bogdan et al. (). | Belsky J | β | 2014 | β |
| Cultural neuroscience: biology of the mind in cultural contexts. | Kim HS et al. | β | 2014 | β |
| Depression is more than the sum score of its parts: individual DSM symptoms have different risk factors. | Fried EI et al. | β | 2014 | β |
| Does self-construal predict activity in the social brain network? A genetic moderation effect. | Ma Y et al. | β | 2014 | β |
| Effects of the serotonin transporter polymorphism and history of major depression on overgeneral autobiographical memory. | Sumner JA et al. | β | 2014 | β |
| Emotion regulation moderates the risk associated with the 5-HTT gene and stress in children. | Ford BQ et al. | β | 2014 | β |
| Emotion: The Self-regulatory Sense. | Peil KT | β | 2014 | β |
| GDM-associated insulin deficiency hinders the dissociation of SERT from ERp44 and down-regulates placental 5-HT uptake. | Li Y et al. | β | 2014 | β |
| Gene-environment interaction. | Manuck SB et al. | β | 2014 | β |
| Lack of association between the 5-HTTLPR and positive screening for mental disorders among children exposed to urban violence and maltreatment. | Cividanes GC et al. | β | 2014 | β |
| On aims and methods of psychiatry - a reminiscence of 50 years of Tinbergen's famous questions about the biology of behavior. | BrΓΌne M | β | 2014 | β |
| Refining the Candidate Environment: Interpersonal Stress, the Serotonin Transporter Polymorphism, and Gene-Environment Interactions in Major Depression. | Vrshek-Schallhorn S et al. | β | 2014 | β |
| Serotonin transporter [corrected] methylation and response to cognitive behaviour therapy in children with anxiety disorders. | Roberts S et al. | β | 2014 | β |
| Stress-system genes and life stress predict cortisol levels and amygdala and hippocampal volumes in children. | Pagliaccio D et al. | β | 2014 | β |
| The association of serotonin transporter gene polymorphism and geriatric depression: a meta-analysis. | Gao Z et al. | β | 2014 | β |
| Trajectories of depressive symptoms in response to prolonged stress in medical interns. | Guille C et al. | β | 2014 | β |
| Acute responsivity of the serotonergic system to S-citalopram and positive emotionality-the moderating role of the 5-HTTLPR. | Wielpuetz C et al. | β | 2013 | β |
| Associations between serotonin transporter polymorphisms and cognitive processing applying the Emo 1-back task. | Jonassen R et al. | β | 2013 | β |
| "Bedside-to-Bench" Behavioral Outcomes in Animal Models of Pain: Beyond the Evaluation of Reflexes. | Cobos EJ et al. | β | 2013 | β |
| Behavioral and neurochemical characterization of maternal care effects on juvenile Sprague-Dawley rats. | MasΓs-Calvo M et al. | β | 2013 | β |
| Beyond the baby blues: perspectives of women diagnosed with a mood disorder on children, pregnancy and medication. | Paterson A et al. | β | 2013 | β |
| Cortisol response to social stress in parentally bereaved youth. | Dietz LJ et al. | β | 2013 | β |
| Differential susceptibility in longitudinal models of gene-environment interaction for adolescent depression. | Li JJ et al. | β | 2013 | β |
| Effect of gene, environment and maternal depressive symptoms on pre-adolescence behavior problems - a longitudinal study. | Agnafors S et al. | β | 2013 | β |
| Implications of the use of genetic tests in psychiatry, with a focus on major depressive disorder: a review. | Wilde A et al. | β | 2013 | β |
| Interaction between the 5-HTTLPR genotype, impact of stressful life events, and trait neuroticism on depressive symptoms in healthy volunteers. | Markus CR | β | 2013 | β |
| Interaction of dopamine transporter gene and observed parenting behaviors on attention-deficit/hyperactivity disorder: a structural equation modeling approach. | Li JJ et al. | β | 2013 | β |
| Internalizing early memories of shame and lack of safeness and warmth: the mediating role of shame on depression. | Matos M et al. | β | 2013 | β |
| Prenatal serotonin reuptake inhibitor (SRI) antidepressant exposure and serotonin transporter promoter genotype (SLC6A4) influence executive functions at 6 years of age. | Weikum WM et al. | β | 2013 | β |
| Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression. | Culverhouse RC et al. | β | 2013 | β |
| Relational interventions for child maltreatment: past, present, and future perspectives. | Toth SL et al. | β | 2013 | β |
| Relational security moderates the effect of serotonin transporter gene polymorphism (5-HTTLPR) on stress generation and depression among adolescents. | Starr LR et al. | β | 2013 | β |
| Religion priming differentially increases prosocial behavior among variants of the dopamine D4 receptor (DRD4) gene. | Sasaki JY et al. | β | 2013 | β |
| Serotonergic modulation of suicidal behaviour: integrating preclinical data with clinical practice and psychotherapy. | Boulougouris V et al. | β | 2013 | β |
| Serotonin transporter genotype and mild traumatic brain injury independently influence resilience and perception of limitations in veterans. | Graham DP et al. | β | 2013 | β |
| The 5-HTTLPR polymorphism in the serotonin transporter gene moderates the association between emotional behavior and changes in marital satisfaction over time. | Haase CM et al. | β | 2013 | β |
| The interaction between child maltreatment, adult stressful life events and the 5-HTTLPR in major depression. | Power RA et al. | β | 2013 | β |
| The role of culture-gene coevolution in morality judgment: examining the interplay between tightness-looseness and allelic variation of the serotonin transporter gene. | Mrazek AJ et al. | β | 2013 | β |
| Well-being and the risk of depression under stress. | Grant F et al. | β | 2013 | β |
| 5-HTTLPR and early childhood adversities moderate cognitive and emotional processing in adolescence. | Owens M et al. | β | 2012 | β |
| 5-HTTLPR S-allele: a genetic plasticity factor regarding the effects of life events on personality? | Kuepper Y et al. | β | 2012 | β |
| An imaging genetics approach to understanding social influence. | Falk EB et al. | β | 2012 | β |
| Differential susceptibility in spillover between interparental conflict and maternal parenting practices: evidence for OXTR and 5-HTT genes. | Sturge-Apple ML et al. | β | 2012 | β |
| Does the oxytocin receptor (OXTR) polymorphism (rs2254298) confer 'vulnerability' for psychopathology or 'differential susceptibility'? Insights from evolution. | BrΓΌne M | β | 2012 | β |
| Fetal serotonin signaling: setting pathways for early childhood development and behavior. | Oberlander TF | β | 2012 | β |
| Gene-environment interaction and the intergenerational transmission of parenting: testing the differential-susceptibility hypothesis. | Beaver KM et al. | β | 2012 | β |
| Genetic contributions to acute autonomic stress responsiveness in children. | Mueller A et al. | β | 2012 | β |
| Genetic moderation of sensitivity to positive and negative affect in marriage. | Schoebi D et al. | β | 2012 | β |
| Genetic sensitivity to the caregiving context: the influence of 5httlpr and BDNF val66met on indiscriminate social behavior. | Drury SS et al. | β | 2012 | β |
| Identification and functional characterization of three novel alleles for the serotonin transporter-linked polymorphic region. | Ehli EA et al. | β | 2012 | β |
| Influence of threat and serotonin transporter genotype on interference effects. | Jasinska AJ et al. | β | 2012 | β |
| Interaction between serotonin transporter polymorphism (5-HTTLPR) and stressful life events in adolescents' trajectories of anxious/depressed symptoms. | Petersen IT et al. | β | 2012 | β |
| Interaction of serotonin transporter linked polymorphic region and childhood neglect on criminal behavior and substance use for males and females. | Vaske J et al. | β | 2012 | β |
| Modeling borderline personality disorder based on the neurobehavioral foundation of major personality traits. | Depue RA et al. | β | 2012 | β |
| Neurodevelopmental outcomes following prenatal exposure to serotonin reuptake inhibitor antidepressants: a "social teratogen" or moderator of developmental risk? | Hanley GE et al. | β | 2012 | β |
| ORCHIDS: an observational randomized controlled trial on childhood differential susceptibility. | Chhangur RR et al. | β | 2012 | β |
| Personality of parents with bipolar disorder and interpersonal functioning among their offspring: a prospective 10-year study. | Ostiguy CS et al. | β | 2012 | β |
| Resilience and measured gene-environment interactions. | Kim-Cohen J et al. | β | 2012 | β |
| Stressful life events and the serotonin transporter gene (5-HTT) in recurrent clinical depression. | Fisher HL et al. | β | 2012 | β |
| Stressful life events, perceived stress, and 12-month course of geriatric depression: direct effects and moderation by the 5-HTTLPR and COMT Val158Met polymorphisms. | Zannas AS et al. | β | 2012 | β |
| The serotonin transporter gene linked polymorphic region is associated with the behavioral response to repeated stress exposure in infant rhesus macaques. | Spinelli S et al. | β | 2012 | β |
| Treatment resistance and psychodynamic psychiatry: concepts psychiatry needs from psychoanalysis. | Plakun E | β | 2012 | β |
| A polymorphism in the serotonin transporter gene moderates cardiovascular reactivity to psychosocial stress. | Way BM et al. | β | 2011 | β |
| A transient placental source of serotonin for the fetal forebrain. | Bonnin A et al. | β | 2011 | β |
| Childhood adversity interacts separately with 5-HTTLPR and BDNF to predict lifetime depression diagnosis. | Carver CS et al. | β | 2011 | β |
| CHRM2, parental monitoring, and adolescent externalizing behavior: evidence for gene-environment interaction. | Dick DM et al. | β | 2011 | β |
| Community interest in predictive genetic testing for susceptibility to major depressive disorder in a large national sample. | Wilde A et al. | β | 2011 | β |
| Cumulative-genetic plasticity, parenting and adolescent self-regulation. | Belsky J et al. | β | 2011 | β |
| Differential genetic susceptibility to child risk at birth in predicting observed maternal behavior. | Fortuna K et al. | β | 2011 | β |
| Differential susceptibility in youth: evidence that 5-HTTLPR x positive parenting is associated with positive affect 'for better and worse'. | Hankin BL et al. | β | 2011 | β |
| Differential susceptibility to the environment: an evolutionary--neurodevelopmental theory. | Ellis BJ et al. | β | 2011 | β |
| Droplets of black bile? Development of vulnerability and resilience to depression in young age. | Harro J et al. | β | 2011 | β |
| Early adversity and adult health outcomes. | Taylor SE et al. | β | 2011 | β |
| Gene-environment interaction in psychological traits and disorders. | Dick DM | β | 2011 | β |
| Gene-environment interactions: early life stress and risk for depressive and anxiety disorders. | Nugent NR et al. | β | 2011 | β |
| Interaction of 5-HTTLPR and idiographic stressors predicts prospective depressive symptoms specifically among youth in a multiwave design. | Hankin BL et al. | β | 2011 | β |
| Interaction of serotonin transporter gene-linked polymorphic region and stressful life events predicts cortisol stress response. | Mueller A et al. | β | 2011 | β |
| Looking on the bright side of serotonin transporter gene variation. | Homberg JR et al. | β | 2011 | β |
| Neurogenetic and experiential processes underlying major personality traits: implications for modelling personality disorders. | Depue RA et al. | β | 2011 | β |
| Perceived discrimination, serotonin transporter linked polymorphic region status, and the development of conduct problems. | Brody GH et al. | β | 2011 | β |
| Prenatal programming of postnatal plasticity? | Pluess M et al. | β | 2011 | β |
| Roles of the placenta in fetal brain development. | Zeltser LM et al. | β | 2011 | β |
| Serotonin transporter polymorphism interacts with childhood adversity to predict aspects of impulsivity. | Carver CS et al. | β | 2011 | β |
| Serotonin transporter polymorphism moderates effects of prenatal maternal anxiety on infant negative emotionality. | Pluess M et al. | β | 2011 | β |
| Social constraints, genetic vulnerability, and mental health following collective stress. | Holman EA et al. | β | 2011 | β |
| The double edged sword of neural plasticity: increasing serotonin levels leads to both greater vulnerability to depression and improved capacity to recover. | Branchi I | β | 2011 | β |
| The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation. | Karg K et al. | β | 2011 | β |
| The winner and loser effect, serotonin transporter genotype, and the display of offensive aggression. | Kloke V et al. | β | 2011 | β |
| Translational research approach to biological and modifiable risk factors of psychosis and affective disorders. | Baune BT et al. | β | 2011 | β |
| War exposure, 5-HTTLPR genotype and lifetime risk of depression. | Artero S et al. | β | 2011 | β |
| 5-HTTLPR moderates effects of current life events on neuroticism: differential susceptibility to environmental influences. | Pluess M et al. | β | 2010 | β |
| A prospective cohort study investigating factors associated with depression during medical internship. | Sen S et al. | β | 2010 | β |
| Are psychosocial factors mediators of socioeconomic status and health connections? A progress report and blueprint for the future. | Matthews KA et al. | β | 2010 | β |
| Biological sensitivity to context: the interactive effects of stress reactivity and family adversity on socioemotional behavior and school readiness. | ObradoviΔ J et al. | β | 2010 | β |
| Chronic and acute stress, gender, and serotonin transporter gene-environment interactions predicting depression symptoms in youth. | Hammen C et al. | β | 2010 | β |
| Cultural Neuroscience. | Ames DL et al. | β | 2010 | β |
| Culture, distress, and oxytocin receptor polymorphism (OXTR) interact to influence emotional support seeking. | Kim HS et al. | β | 2010 | β |
| Culture-gene coevolution of individualism-collectivism and the serotonin transporter gene. | Chiao JY et al. | β | 2010 | β |
| Culture, serotonin receptor polymorphism and locus of attention. | Kim HS et al. | β | 2010 | β |
| Current developments and controversies: does the serotonin transporter gene-linked polymorphic region (5-HTTLPR) modulate the association between stress and depression? | Wankerl M et al. | β | 2010 | β |
| From nature versus nurture, via nature and nurture, to gene x environment interaction in mental disorders. | Wermter AK et al. | β | 2010 | β |
| Gene-environment interactions and response to social intrusion in male and female rhesus macaques. | Schwandt ML et al. | β | 2010 | β |
| Health disparities across the lifespan: meaning, methods, and mechanisms. | Adler NE et al. | β | 2010 | β |
| Incorporating the social environment in genotype environment interaction studies of mental disorders. | Koenen KC et al. | β | 2010 | β |
| Is there a genetic contribution to cultural differences? Collectivism, individualism and genetic markers of social sensitivity. | Way BM et al. | β | 2010 | β |
| Latent class analysis of antisocial behavior: interaction of serotonin transporter genotype and maltreatment. | Li JJ et al. | β | 2010 | β |
| Life course perspectives on the epidemiology of depression. | Colman I et al. | β | 2010 | β |
| Mechanisms linking early life stress to adult health outcomes. | Taylor SE | β | 2010 | β |
| Neural and behavioral responses to threatening emotion faces in children as a function of the short allele of the serotonin transporter gene. | Thomason ME et al. | β | 2010 | β |
| Neurobiological adaptations to violence across development. | Mead HK et al. | β | 2010 | β |
| Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms. | Ressler KJ et al. | β | 2010 | β |
| Profile of Shelley E. Taylor. Interview by Beth Azar. | Taylor SE | β | 2010 | β |
| Public interest in predictive genetic testing, including direct-to-consumer testing, for susceptibility to major depression: preliminary findings. | Wilde A et al. | β | 2010 | β |
| Serotonin transporter gene, childhood emotional abuse and cognitive vulnerability to depression. | Antypa N et al. | β | 2010 | β |
| Social influences on health: is serotonin a critical mediator? | Way BM et al. | β | 2010 | β |
| Socio-economic differentials in peripheral biology: cumulative allostatic load. | Seeman T et al. | β | 2010 | β |
| The combined effects of the BDNF and GSK3B genes modulate the relationship between negative life events and major depressive disorder. | Yang C et al. | β | 2010 | β |
| The heritability of postpartum depression. | Corwin EJ et al. | β | 2010 | β |
| The serotonin transporter polymorphism (5-HTTLPR): allelic variation and links with depressive symptoms. | Goldman N et al. | β | 2010 | β |
| The serotonin transporter promoter polymorphism is associated with cortisol response to psychosocial stress. | Way BM et al. | β | 2010 | β |
| 5HTT polymorphisms are associated with job stress in Japanese workers. | Katsuyama H et al. | β | 2009 | β |
| Association of adverse childhood environment and 5-HTTLPR Genotype with late-life depression. | Ritchie K et al. | β | 2009 | β |
| Clinical implications of genetic variation in the serotonin transporter promoter region: a review. | Luddington NS et al. | β | 2009 | β |
| Community attitudes towards mental health interventions for healthy people on the basis of genetic susceptibility. | Wilde A et al. | β | 2009 | β |
| Cultural consonance, a 5HT2A receptor polymorphism, and depressive symptoms: a longitudinal study of gene x culture interaction in urban Brazil. | Dressler WW et al. | β | 2009 | β |
| Culture and social support: neural bases and biological impact. | Sherman DK et al. | β | 2009 | β |
| Developmental influences on medically unexplained symptoms. | Buffington CA | β | 2009 | β |
| Development and validation of the high-quality 'rapid method for swab' to genotype the HTTLPR serotonin transporter (SLC6A4) promoter polymorphism. | Maloney B et al. | β | 2009 | β |
| Development of an early memories of warmth and safeness scale and its relationship to psychopathology. | Richter A et al. | β | 2009 | β |
| Differential susceptibility to rearing experience: the case of childcare. | Pluess M et al. | β | 2009 | β |
| Effects of stressful life events, maternal depression and 5-HTTLPR genotype on emotional symptoms in pre-adolescent children. | Araya R et al. | β | 2009 | β |
| Emotional distress in parents of psychotic patients is modified by serotonin transporter gene (5-HTTLPR)--brain-derived neurotrophic factor gene interactions. | Golimbet V et al. | β | 2009 | β |
| Genetic and non-genetic influences on the development of co-occurring alcohol problem use and internalizing symptomatology in adolescence: a review. | Saraceno L et al. | β | 2009 | β |
| Genetic, environmental, and epigenetic factors in the development of personality disturbance. | Depue RA | β | 2009 | β |
| Gene X environment interactions at the serotonin transporter locus. | MunafΓ² MR et al. | β | 2009 | β |
| Habits of the heart: life history and the developmental neuroendocrinology of emotion. | Worthman CM | β | 2009 | β |
| Impact of the interaction between the 5HTTLPR polymorphism and maltreatment on adolescent depression. A population-based study. | Aslund C et al. | β | 2009 | β |
| Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. | Risch N et al. | β | 2009 | β |
| Interaction of 5HTTLPR and marijuana use on property offending. | Vaske J et al. | β | 2009 | β |
| Interpersonal functioning in adolescent offspring of parents with bipolar disorder. | Linnen AM et al. | β | 2009 | β |
| Modification of the association between serotonin transporter genotype and risk of posttraumatic stress disorder in adults by county-level social environment. | Koenen KC et al. | β | 2009 | β |
| Multifinality in the development of personality disorders: a Biology x Sex x Environment interaction model of antisocial and borderline traits. | Beauchaine TP et al. | β | 2009 | β |
| Parenting moderates a genetic vulnerability factor in longitudinal increases in youths' substance use. | Brody GH et al. | β | 2009 | β |
| Prenatal smoking and attention-deficit/hyperactivity disorder: DRD4-7R as a plasticity gene. | Pluess M et al. | β | 2009 | β |
| Prevention effects moderate the association of 5-HTTLPR and youth risk behavior initiation: gene x environment hypotheses tested via a randomized prevention design. | Brody GH et al. | β | 2009 | β |
| Psychological vulnerability differences in students--carriers or not of the serotonin transporter promoter allele S: effect of adverse experiences. | Veletza S et al. | β | 2009 | β |
| Serotonin transporter gene variation and stressful life events impact processing of fear and anxiety. | Armbruster D et al. | β | 2009 | β |
| The Nature (and Nurture?) of Plasticity in Early Human Development. | Belsky J et al. | β | 2009 | β |
| Vulnerability genes or plasticity genes? | Belsky J et al. | β | 2009 | β |
| Allostatic load in bipolar disorder: implications for pathophysiology and treatment. | Kapczinski F et al. | β | 2008 | β |
| A serotonin transporter gene polymorphism (5-HTTLPR), drinking-to-cope motivation, and negative life events among college students. | Armeli S et al. | β | 2008 | β |
| [Cerebral images in bipolar disorder]. | Gaillard R | β | 2008 | β |
| Depression and the serotonin transporter 5-HTTLPR polymorphism: a review and a hypothesis concerning gene-environment interaction. | Brown GW et al. | β | 2008 | β |
| Early childhood adversity and adolescent depression: the mediating role of continued stress. | Hazel NA et al. | β | 2008 | β |
| Gender differences in response to emotional stress: an assessment across subjective, behavioral, and physiological domains and relations to alcohol craving. | Chaplin TM et al. | β | 2008 | β |
| Gene-environment interactions in depression research: genetic polymorphisms and life-stress polyprocedures. | Monroe SM et al. | β | 2008 | β |
| Genetic contributions to sensitive parenting. | Taylor SE | β | 2008 | β |
| Genetics of nicotine dependence and pharmacotherapy. | Lessov-Schlaggar CN et al. | β | 2008 | β |
| Serotonergic function, two-mode models of self-regulation, and vulnerability to depression: what depression has in common with impulsive aggression. | Carver CS et al. | β | 2008 | β |
| The effect of 5-HTT gene promoter polymorphism on impulsivity depends on family relations in girls. | Paaver M et al. | β | 2008 | β |
| The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis. | Uher R et al. | β | 2008 | β |
| Adolescents' perceived weight associated with depression in young adulthood: a longitudinal study. | Al Mamun A et al. | β | 2007 | β |
| Coping resources, coping processes, and mental health. | Taylor SE et al. | β | 2007 | β |
| Cultural differences in the impact of social support on psychological and biological stress responses. | Taylor SE et al. | β | 2007 | β |
| [Depression and stress: is there an endophenotype?]. | Mello AF et al. | β | 2007 | β |
| Genetically informative designs in the study of resilience in developmental psychopathology. | Bartels M et al. | β | 2007 | β |
| Interactions between life stressors and susceptibility genes (5-HTTLPR and BDNF) on depression in Korean elders. | Kim JM et al. | β | 2007 | β |
| Platelet MAO activity and the 5-HTT gene promoter polymorphism are associated with impulsivity and cognitive style in visual information processing. | Paaver M et al. | β | 2007 | β |
| Serotonin transporter polymorphism, memory and hippocampal volume in the elderly: association and interaction with cortisol. | O'Hara R et al. | β | 2007 | β |
| Stress and its consequences: an evolving story. | Kaufman J | β | 2006 | β |