NMDAR drug
Evidence from:
primary |
all sources
Related entities (23)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| APV | interacts_with | NMDAR | — | 1 |
| CRF | regulates | NMDAR | — | 1 |
| CRF2R | regulates | NMDAR | — | 1 |
| de novo variant | associated_with | NMDAR | — | 1 |
| Dlg4 | interacts_with | NMDAR | — | 1 |
| ERBB4 | interacts_with | NMDAR | — | 1 |
| ethanol group | targets | NMDAR | — | 1 |
| ethanol group | interacts_with | NMDAR | — | 1 |
| ethanol group | regulates | NMDAR | — | 1 |
| EtOH | interacts_with | NMDAR | — | 1 |
| EtOH | associated_with | NMDAR | — | 1 |
| EtOH | regulates | NMDAR | — | 1 |
| MHC locus | interacts_with | NMDAR | — | 1 |
| NMDAR | associated_with | cognition | — | 1 |
| NMDAR | regulates | dentate gyrus | — | 1 |
| NMDAR | expressed_in | dopaminergic neurons | — | 1 |
| NMDAR | risk_factor_for | excitotoxicity | — | 1 |
| NMDAR | associated_with | learning and memory | — | 1 |
| NMDAR | regulates | long-term potentiation | — | 1 |
| NMDAR | regulates | LTP | — | 1 |
| NMDAR | associated_with | neuroprotection | — | 1 |
| NMDAR | regulates | synaptic plasticity | — | 1 |
| NRG1 | interacts_with | NMDAR | — | 1 |
Mentioned in (34)
Papers in which this entity is mentioned.
- Reduction of APOE accounts for neurobehavioral deficits in fetal alcohol spectrum disorders. (2024)
- A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline. (2021)
- PKA and Ube3a regulate SK2 channel trafficking to promote synaptic plasticity in hippocampus: Implications for Angelman Syndrome. (2020)
- Transient Potassium Channels: Therapeutic Targets for Brain Disorders. (2019)
- SK Channel Modulates Synaptic Plasticity by Tuning CaMKIIα/β Dynamics. (2019)
- Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood. (2018)
- Alcohol and the Brain: Neuronal Molecular Targets, Synapses, and Circuits. (2017)
- ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease. (2017)
- Thalamocortical Projections onto Behaviorally Relevant Neurons Exhibit Plasticity during Adult Motor Learning. (2016)
- Increasing the GluN2A/GluN2B Ratio in Neurons of the Mouse Basal and Lateral Amygdala Inhibits the Modification of an Existing Fear Memory Trace. (2016)
- Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings. (2016)
- Recent genetic findings in schizophrenia and their therapeutic relevance. (2015)
- Moderate prenatal alcohol exposure enhances GluN2B containing NMDA receptor binding and ifenprodil sensitivity in rat agranular insular cortex. (2015)
- Modeling hippocampal neurogenesis using human pluripotent stem cells. (2014)
- Prenatal alcohol exposure is associated with altered subcellular distribution of glucocorticoid and mineralocorticoid receptors in the adolescent mouse hippocampal formation. (2014)
- Cornichon proteins determine the subunit composition of synaptic AMPA receptors. (2013)
- LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype. (2013)
- Rethinking schizophrenia in the context of normal neurodevelopment. (2013)
- Hedgehog agonist therapy corrects structural and cognitive deficits in a Down syndrome mouse model. (2013)
- Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus. (2013)
- Role of motor cortex NMDA receptors in learning-dependent synaptic plasticity of behaving mice. (2013)
- The ubiquitin-proteasome system as a critical regulator of synaptic plasticity and long-term memory formation. (2013)
- Synaptic effects induced by alcohol. (2013)
- Stress-related neuropeptides and addictive behaviors: beyond the usual suspects. (2012)
- CNVs: harbingers of a rare variant revolution in psychiatric genetics. (2012)
- Fetal alcohol spectrum disorders and abnormal neuronal plasticity. (2011)
- PDZ binding of TARPγ-8 controls synaptic transmission but not synaptic plasticity. (2011)
- Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration. (2010)
- Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning. (2010)
- Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders. (2010)
- Down syndrome--recent progress and future prospects. (2009)
- Deletion of glycine transporter 1 (GlyT1) in forebrain neurons facilitates reversal learning: enhanced cognitive adaptability? (2009)
- Defects in embryonic neurogenesis and initial synapse formation in the forebrain of the Ts65Dn mouse model of Down syndrome. (2007)
- Decline of the critical period of visual plasticity is concurrent with the reduction of NR2B subunit of the synaptic NMDA receptor in layer 4. (2003)
Merged raw entities (4)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| nmdar | drug | 31 | 78 |
| nmdar | gene | 8 | 8 |
| nmdar-mediated activity | drug | — | — |
| nmdar signalling | drug | — | — |