CHEK2 gene
Evidence from:
primary |
all sources
Related entities (1)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| ATM | regulates | CHEK2 | — | 1 |
Mentioned in (29)
Papers in which this entity is mentioned.
- Whole genome sequencing approach to assess homologous recombination deficiency in a pan-cancer cohort. (2026)
- Stratified Medicine Pediatrics: Cell-Free DNA and Serial Tumor Sequencing Identifies Subtype-Specific Cancer Evolution and Epigenetic States. (2025)
- FET fusion oncoproteins disrupt physiologic DNA repair and create a targetable opportunity for ATR inhibitor therapy. (2025)
- CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods. (2024)
- Heritable defects in telomere and mitotic function selectively predispose to sarcomas. (2023)
- Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors. (2021)
- Therapeutic Implications of Germline Testing in Patients With Advanced Cancers. (2021)
- Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors. (2020)
- Comprehensive analysis of structural variants in breast cancer genomes using single-molecule sequencing. (2020)
- Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study. (2019)
- A Compendium of Mutational Signatures of Environmental Agents. (2019)
- Comprehensive analysis of structural variants in breast cancer genomes using single molecule sequencing (2019)
- Pan-cancer whole-genome analyses of metastatic solid tumours. (2019)
- Mutational processes shape the landscape of TP53 mutations in human cancer. (2018)
- Comprehensive Characterization of Cancer Driver Genes and Mutations. (2018)
- Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes. (2018)
- Patterns and mechanisms of structural variations in human cancer. (2018)
- HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures. (2017)
- Landscape of somatic mutations in 560 breast cancer whole-genome sequences. (2016)
- Germline Mutations in Predisposition Genes in Pediatric Cancer. (2015)
- Spontaneous ATM Gene Reversion in A-T iPSC to Produce an Isogenic Cell Line. (2015)
- Involvement of p53 in the repair of DNA double strand breaks: multifaceted Roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ). (2014)
- Ewing sarcoma protein: a key player in human cancer. (2013)
- Large-scale genotyping identifies 41 new loci associated with breast cancer risk. (2013)
- RNA splicing: a new player in the DNA damage response. (2013)
- Regulation of cancer progression by β-endorphin neuron. (2012)
- BRCA1 and BRCA2: different roles in a common pathway of genome protection. (2011)
- Gene--environment-wide association studies: emerging approaches. (2010)
- MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings. (2008)
Merged raw entities (2)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| chek2 | gene | 28 | 61 |
| chk2 | gene | 7 | 18 |