Large-scale genotyping identifies 41 new loci associated with breast cancer risk.

paper Cited Public

Authors: Michailidou, Kyriaki; Hall, Per; Gonzalez-Neira, Anna; Ghoussaini, Maya; Dennis, Joe; Milne, Roger L; Schmidt, Marjanka K; Chang-Claude, Jenny; Bojesen, Stig E; Bolla, Manjeet K; Wang, Qin; Dicks, Ed; Lee, Andrew; Turnbull, Clare; Rahman, Nazneen; Breast and Ovarian Cancer Susceptibility Collaboration; Fletcher, Olivia; Peto, Julian; Gibson, Lorna; Dos Santos Silva, Isabel; Nevanlinna, Heli; Muranen, Taru A; Aittomäki, Kristiina; Blomqvist, Carl; Czene, Kamila; Irwanto, Astrid; Liu, Jianjun; Waisfisz, Quinten; Meijers-Heijboer, Hanne; Adank, Muriel; Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON); van der Luijt, Rob B; Hein, Rebecca; Dahmen, Norbert; Beckman, Lars; Meindl, Alfons; Schmutzler, Rita K; Müller-Myhsok, Bertram; Lichtner, Peter; Hopper, John L; Southey, Melissa C; Makalic, Enes; Schmidt, Daniel F; Uitterlinden, Andre G; Hofman, Albert; Hunter, David J; Chanock, Stephen J; Vincent, Daniel; Bacot, François; Tessier, Daniel C; Canisius, Sander; Wessels, Lodewyk F A; Haiman, Christopher A; Shah, Mitul; Luben, Robert; Brown, Judith; Luccarini, Craig; Schoof, Nils; Humphreys, Keith; Li, Jingmei; Nordestgaard, Børge G; Nielsen, Sune F; Flyger, Henrik; Couch, Fergus J; Wang, Xianshu; Vachon, Celine; Stevens, Kristen N; Lambrechts, Diether; Moisse, Matthieu; Paridaens, Robert; Christiaens, Marie-Rose; Rudolph, Anja; Nickels, Stefan; Flesch-Janys, Dieter; Johnson, Nichola; Aitken, Zoe; Aaltonen, Kirsimari; Heikkinen, Tuomas; Broeks, Annegien; Veer, Laura J Van't; van der Schoot, C Ellen; Guénel, Pascal; Truong, Thérèse; Laurent-Puig, Pierre; Menegaux, Florence; Marme, Frederik; Schneeweiss, Andreas; Sohn, Christof; Burwinkel, Barbara; Zamora, M Pilar; Perez, Jose Ignacio Arias; Pita, Guillermo; Alonso, M Rosario; Cox, Angela; Brock, Ian W; Cross, Simon S; Reed, Malcolm W R; Sawyer, Elinor J; Tomlinson, Ian; Kerin, Michael J; Miller, Nicola; Henderson, Brian E; Schumacher, Fredrick; Le Marchand, Loic; Andrulis, Irene L; Knight, Julia A; Glendon, Gord; Mulligan, Anna Marie; kConFab Investigators; Australian Ovarian Cancer Study Group; Lindblom, Annika; Margolin, Sara; Hooning, Maartje J; Hollestelle, Antoinette; van den Ouweland, Ans M W; Jager, Agnes; Bui, Quang M; Stone, Jennifer; Dite, Gillian S; Apicella, Carmel; Tsimiklis, Helen; Giles, Graham G; Severi, Gianluca; Baglietto, Laura; Fasching, Peter A; Haeberle, Lothar; Ekici, Arif B; Beckmann, Matthias W; Brenner, Hermann; Müller, Heiko; Arndt, Volker; Stegmaier, Christa; Swerdlow, Anthony; Ashworth, Alan; Orr, Nick; Jones, Michael; Figueroa, Jonine; Lissowska, Jolanta; Brinton, Louise; Goldberg, Mark S; Labrèche, France; Dumont, Martine; Winqvist, Robert; Pylkäs, Katri; Jukkola-Vuorinen, Arja; Grip, Mervi; Brauch, Hiltrud; Hamann, Ute; Brüning, Thomas; GENICA (Gene Environment Interaction and Breast Cancer in Germany) Network; Radice, Paolo; Peterlongo, Paolo; Manoukian, Siranoush; Bonanni, Bernardo; Devilee, Peter; Tollenaar, Rob A E M; Seynaeve, Caroline; van Asperen, Christi J; Jakubowska, Anna; Lubinski, Jan; Jaworska, Katarzyna; Durda, Katarzyna; Mannermaa, Arto; Kataja, Vesa; Kosma, Veli-Matti; Hartikainen, Jaana M; Bogdanova, Natalia V; Antonenkova, Natalia N; Dörk, Thilo; Kristensen, Vessela N; Anton-Culver, Hoda; Slager, Susan; Toland, Amanda E; Edge, Stephen; Fostira, Florentia; Kang, Daehee; Yoo, Keun-Young; Noh, Dong-Young; Matsuo, Keitaro; Ito, Hidemi; Iwata, Hiroji; Sueta, Aiko; Wu, Anna H; Tseng, Chiu-Chen; Van Den Berg, David; Stram, Daniel O; Shu, Xiao-Ou; Lu, Wei; Gao, Yu-Tang; Cai, Hui; Teo, Soo Hwang; Yip, Cheng Har; Phuah, Sze Yee; Cornes, Belinda K; Hartman, Mikael; Miao, Hui; Lim, Wei Yen; Sng, Jen-Hwei; Muir, Kenneth; Lophatananon, Artitaya; Stewart-Brown, Sarah; Siriwanarangsan, Pornthep; Shen, Chen-Yang; Hsiung, Chia-Ni; Wu, Pei-Ei; Ding, Shian-Ling; Sangrajrang, Suleeporn; Gaborieau, Valerie; Brennan, Paul; McKay, James; Blot, William J; Signorello, Lisa B; Cai, Qiuyin; Zheng, Wei; Deming-Halverson, Sandra; Shrubsole, Martha; Long, Jirong; Simard, Jacques; Garcia-Closas, Montse; Pharoah, Paul D P; Chenevix-Trench, Georgia; Dunning, Alison M; Benitez, Javier; Easton, Douglas F
Year: 2013
Journal: Nature genetics
PMID: 23535729
DOI: 10.1038/ng.2563
PMCID: PMC3771688

#	Section	Preview
0	RESULTS	To identify additional susceptibility loci for breast cancer, we first conducted a meta-analysis of…
1	RESULTS	ovarian cancers in BRCA1 and BRCA2 mutation carriers (COGS)17–20. The array included, in addition…
2	RESULTS	The association between each SNP and breast cancer risk was tested using a 1-degree-of-freedom trend…
3	RESULTS	the combined GWAS data set, 10,864 (51%) had effects in the same direction in the GWAS and iCOGS…
4	RESULTS	with significant association at P < 0.00001, 21 were within 1 Mb of 1 of the newly identified breast…
5	RESULTS	Of the 27 previously established breast cancer–associated loci, all but 4 showed clear evidence of…
6	RESULTS — Identification of new susceptibility loci	When the results from the GWAS and the iCOGS array were combined, 263 SNPs in 37 new regions had…
7	RESULTS — Identification of new susceptibility loci	and rs720475) for which the heterozygotes had a similar OR as homozygotes for the high-risk allele…
8	RESULTS — Identification of new susceptibility loci	OR = 0.94 (95% CI = 0.90–0.98); P for difference = 3.1 × 10−10). No such difference was…
9	RESULTS — Identification of new susceptibility loci	Four of the newly associated loci (rs16857609 at 2q35, rs10759243 at 9q31, rs11199914 at 10q26 and…
10	RESULTS — Identification of new susceptibility loci	Two associated loci lie within or close to known breast cancer susceptibility genes. rs11571833 is a…
11	RESULTS — Identification of new susceptibility loci	In addition to rs11571833, one further SNP is a coding variant: rs11552449 encodes a missense…
12	RESULTS — Identification of new susceptibility loci	analysis of candidate SNPs in Asian populations identified SNP rs1078985 as a potential breast…
13	RESULTS — Identification of new susceptibility loci	The identification of the genes and variants underlying these associations will require more…
14	RESULTS — Identification of new susceptibility loci	Three loci are located in the vicinity of susceptibility regions for other cancer types. SNP…
15	RESULTS — Identification of new susceptibility loci	encodes a methylcytosine dioxygenase involved in myelopoiesis. Mutations in TET2 are frequent in…
16	RESULTS — Identification of new susceptibility loci	To further investigate the likely genes underlying the susceptibility variants, we examined…
17	RESULTS — Identification of new susceptibility loci	= 0.01) in lymphoblastoid cell lines from HapMap samples using the Genevar database35 (Supplementary…
18	RESULTS — Identification of new susceptibility loci	In addition to the genes described above, plausible candidate genes exist in several of the newly…
19	RESULTS — Identification of new susceptibility loci	induce mesenchymal-epithelial transition44. Dysfunctional ARHGEF5 acts as an oncogene specific for…

Name	Type
1000 Genomes Project	cohort
10,668 SNPs selected from the GWAS local	variant
10 loci local	variant
1,168 loci selected from the GWAS local	variant
41 newly associated loci local	variant
67 established loci local	variant
8q24 region local	other
920 loci local	variant
Affymetrix Genome-Wide Human SNP 6.0 array local	drug
Affymetrix SNP array local	drug
African-Americans	cohort
age at diagnosis local	phenotype
Agilent 244K expression array local	drug
apoptosis	phenotype
ARHGEF5 local	gene
Asian	cohort
BBCS local	cohort
BCAC local	cohort
BCAC analyses local	cohort
BRCA1	gene
BRCA2	gene
breast cancer	phenotype
breast cancer loci local	variant
breast cancer risk	phenotype
breast cancer susceptibility loci local	variant
breast tumor local	phenotype
breast tumors local	phenotype
cancer susceptibility loci local	phenotype
candidate genes	cohort
CASP8	gene
CCND1 local	gene
cell migration	phenotype
cell proliferation	phenotype
CEU population	cohort
CFL1	gene
CHEK2	gene
CHEK2 c.1100delC local	variant
CIMBA local	cohort
COGS	cohort
COGS consortia local	cohort
combined breast cancer GWAS local	cohort
common variants	cohort
COSMIC local	cohort
CTSW local	gene
DCIS local	phenotype
DCLRE1B local	gene
DFBBCS local	cohort
disease	phenotype
DNAJC1 local	gene
DNA repair local	phenotype
East Asian	cohort
EMID1 local	gene
eQTLGen Consortium	cohort
ER-negative breast local	phenotype
ER-negative breast tumor local	phenotype
ER-negative disease local	phenotype
ER-positive breast local	phenotype
ER-positive breast tumor local	phenotype
ER-positive disease local	phenotype
ER status local	phenotype
estrogen receptor-negative breast cancer local	phenotype
European ancestry	cohort
European population	cohort
Europeans	cohort
familial breast cancer local	phenotype
familial cases	cohort
familial risk	cohort
family history positive	phenotype
first six principal components local	drug
FOXQ1 local	gene
FTO	gene
GC-HBOC local	cohort
gene expression	phenotype
genes	gene
genome-wide significant association local	phenotype
genomic stability local	phenotype
GWAS	cohort
GWAS-selected SNPs local	variant
HapMap	cohort
HapMap 2 populations local	cohort
HapMap3	cohort
HapMap CEU	cohort
HapMap version 2 CEU local	cohort
HapMap version 2 JPT/CHB local	cohort
HapMap version 2 YRI local	cohort
HEBCS local	cohort
hematological malignancies local	phenotype
higher penetrance loci local	variant
human breast carcinoma local	phenotype
iCOGS local	cohort
iCOGS array local	cohort
iCOGS stage local	cohort
iCOGS Stage local	cohort
Illumina Infinium array (iCOGS) local	drug
invasive local	phenotype
invasive disease local	phenotype
KREMEN1 local	gene
lead SNP	cohort
LMBC local	cohort
loci	cohort
mammary gland function local	phenotype
mesenchymal-epithelial transition local	phenotype
metastasis	phenotype
MKL1 local	gene
MUS81 local	gene
MYBRCA local	cohort
Myc	gene
MYC33 local	gene
NBHS local	cohort
neuronal differentiation	phenotype
newly identified breast cancer loci local	variant
new region local	anatomy
new SNPs local	variant
nine breast cancer GWAS local	cohort
nine component studies local	cohort
nine GWAS local	cohort
normal breast tissue local	phenotype
Northern and Western European ancestry	cohort
NTN4 local	gene
obesity	phenotype
OCAC local	cohort
ovarian cancer	phenotype
overall breast cancer risk local	phenotype
PAX9 local	gene
per-allele OR local	phenotype
PEX14 local	gene
PRACTICAL local	cohort
prostate cancer	phenotype
proxy SNPs	variant
PTH1R local	gene
PTHLH	gene
PTPN22	gene
RAD51B local	gene
risk-associated SNPs local	variant
rs10088218 local	variant
rs1045485 local	variant
rs10483813 local	variant
rs10759243 local	variant
rs1078985 local	variant
rs11199914 local	variant
rs11242675 local	variant
rs11552449 local	variant
rs11571833 local	variant
rs11780156 local	variant
rs11814448 local	variant
rs1217396 local	variant
rs12255372 local	variant
rs1243180 local	variant
rs12493607 local	variant
rs132390 local	variant
rs16857609 local	variant
rs17817449 local	variant
rs204247 local	variant
rs2284378 local	variant
rs2380205 local	variant
rs2588809 local	variant
rs3760982 local	variant
rs3760983 local	variant
rs3903072 local	variant
rs4522809 local	variant
rs616402 local	variant
rs616488 local	variant
rs6472903 local	variant
rs6828523 local	variant
rs7072776 local	variant
rs720475 local	variant
rs7679673 local	variant
rs7904519 local	variant
rs8170 local	variant
rs941764 local	variant
rs9790517 local	variant
rs999737 local	variant
SCCS local	cohort
schizophrenia	phenotype
seventh component local	drug
SGBCC local	cohort
SNP	cohort
SNPs selected on the basis of an association in the combined breast cancer GWAS local	variant
South Asian ancestry local	phenotype
SSBP4 local	gene
TCF7L2	gene
TCGA	cohort
TCGA breast cancer study local	cohort
TERT	gene
TET2	gene
TGFBR2 local	gene
tumor aggressiveness local	phenotype
tumor cell invasion local	phenotype
tumor cell motility local	phenotype
tumor expression local	phenotype
tumor growth	phenotype
tumorigenesis	phenotype
tumor incidence local	phenotype
tumor invasiveness local	phenotype
tumor subtype local	phenotype
two principal components local	drug
type 2 diabetes	phenotype
UK2 local	cohort
WTCCC2	cohort
young age local	phenotype
Zellweger syndrome local	phenotype
ZNF222 local	gene
ZNF283 local	gene
ZNF404 local	gene
ZNF45 local	gene

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In this knowledge base

Title	Year	PMID
The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog).	2017	27899670
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.	2014	25231870
Gene-environment interactions in cancer epidemiology: a National Cancer Institute Think Tank report.	2013	24123198

External

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Hereditary Breast Cancer: Comprehensive Risk Assessment and Prevention Strategies.	Manna EDF et al.	—	2025	→
Identification and characterization of lLF2 as a prognostic biomarker in HER2-positive breast cancer using Mendelian randomization and machine learning.	Quan X et al.	—	2025	→
Integrating breast cancer polygenic risk scores at scale in the WISDOM Study: a national randomized personalized screening trial.	Fergus KB et al.	—	2025	→
Lessons learned from a candidate gene study investigating aromatase inhibitor treatment outcome in breast cancer.	Hoppe R et al.	—	2025	→
Polygenic risk score for breast cancer risk prediction in Asian BRCA1 and BRCA2 pathogenic variants carriers.	Tai MC et al.	—	2025	→
Polygenic risk score prediction accuracy convergence.	Henches L et al.	—	2025	→
Protein N-terminal modifications: molecular machineries and biological implications.	Øye H et al.	—	2025	→
rs604702 confers breast cancer risk by influencing PCAT18/miR-759/SPRR3 axis.	Zhang XX et al.	—	2025	→
Update Breast Cancer 2024 Part 2 - Patients with Early Stage Breast Cancer.	Janni W et al.	—	2025	→
A multi-tissue, splicing-based joint transcriptome-wide association study identifies susceptibility genes for breast cancer.	Gao G et al.	—	2024	→
A proteome-wide association study identifies putative causal proteins for breast cancer risk.	Zhao T et al.	—	2024	→
Association between programmed death protein 1-related single-nucleotide polymorphisms and immune-related adverse events induced by programmed death protein 1 inhibitors-a pilot study.	Cai L et al.	—	2024	→
BRCA1/2 Mutations and Breast/Ovarian Cancer Risk: A New Insights Review.	Pourmasoumi P et al.	—	2024	→
Cancer risks among first-degree relatives of women with a genetic predisposition to breast cancer.	Xiao Q et al.	—	2024	→
CDK4/6 Inhibition - Therapy Sequences and the Quest to Find the Best Biomarkers - an Overview of Current Programs.	Schneeweiss A et al.	—	2024	→
Cis- and trans-eQTL TWASs of breast and ovarian cancer identify more than 100 susceptibility genes in the BCAC and OCAC consortia.	Head ST et al.	—	2024	→
Differentiated genomic footprints suggest isolation and long-distance migration of Hmong-Mien populations.	He G et al.	—	2024	→
Gender-Specific Genetic Predisposition to Breast Cancer: <i>BRCA</i> Genes and Beyond.	Valentini V et al.	—	2024	→
Genetic drivers and cellular selection of female mosaic X chromosome loss.	Liu A et al.	—	2024	→
Genetic Variants and Haplotype Structures in the <i>CASC</i> Gene Family to Predict Cancer Risk: A Bioinformatics Study.	Gholami M et al.	—	2024	→
Germline polygenic risk scores are associated with immune gene expression signature and immune cell infiltration in breast cancer.	Liu Y et al.	—	2024	→
<i>MLIP</i> and Its Potential Influence on Key Oncogenic Pathways.	Hamwi MN et al.	—	2024	→
Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions.	Dareng EO et al.	—	2024	→
Interaction of breast cancer-relevant DNA repair genes and air pollution in relation to breast cancer risk in UK biobank.	Smotherman C et al.	—	2024	→
Investigating the shared genetic architecture between breast and ovarian cancers.	Shi X et al.	—	2024	→
New Paradigms in the Clinical Management of Li-Fraumeni Syndrome.	Giovino C et al.	—	2024	→
Novel breast cancer susceptibility loci under linkage peaks identified in African ancestry consortia.	Ochs-Balcom HM et al.	—	2024	→
Polygenic Risk Score (PRS) Combined with NGS Panel Testing Increases Accuracy in Hereditary Breast Cancer Risk Estimation.	Tsoulos N et al.	—	2024	→
Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction.	Yiangou K et al.	—	2024	→
Population-specific validation and comparison of the performance of 77- and 313-variant polygenic risk scores for breast cancer risk prediction.	Hovhannisyan M et al.	—	2024	→
Potential interplay between tumor size and vitamin D receptor (VDR) polymorphisms in breast cancer prognosis: a prospective cohort study.	Lindgren H et al.	—	2024	→
Precision Oncology in Breast Cancer Surgery.	Abbasi AB et al.	—	2024	→
The impact of circulating protein levels identified by affinity proteomics on short-term, overall breast cancer risk.	Grassmann F et al.	—	2024	→
Towards functional maps of non-coding variants in cancer.	Wang Y et al.	—	2024	→
A genome-wide gene-environment interaction study of breast cancer risk for women of European ancestry.	Middha P et al.	—	2023	→
Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry.	Mueller SH et al.	—	2023	→
An apparent quandary: adoption of polygenics and gene panels for personalised breast cancer risk stratification.	Lanchbury JS et al.	—	2023	→
Application of Novel Breast Biospecimen Cell-Type Adjustment Identifies Shared DNA Methylation Alterations in Breast Tissue and Milk with Breast Cancer-Risk Factors.	Muse ME et al.	—	2023	→
A Single nucleotide polymorphism in the ALDH2 gene modifies the risk of esophageal squamous cell carcinoma in BRCA2 p.K3326* carriers.	Zamani N et al.	—	2023	→
Association and performance of polygenic risk scores for breast cancer among French women presenting or not a familial predisposition to the disease.	Jiao Y et al.	—	2023	→
Associations of a Breast Cancer Polygenic Risk Score With Tumor Characteristics and Survival.	Lopes Cardozo JMN et al.	—	2023	→
A Swedish Familial Genome-Wide Haplotype Analysis Identified Five Novel Breast Cancer Susceptibility Loci on 9p24.3, 11q22.3, 15q11.2, 16q24.1 and Xq21.31.	Barnekow E et al.	—	2023	→
BGWAS: Bayesian variable selection in linear mixed models with nonlocal priors for genome-wide association studies.	Williams J et al.	—	2023	→
Caveolin-1 genotypes as predictor for locoregional recurrence and contralateral disease in breast cancer.	Godina C et al.	—	2023	→
Clinical applicability of the Polygenic Risk Score for breast cancer risk prediction in familial cases.	Lakeman IMM et al.	—	2023	→
Clinical utility of polygenic risk scores: a critical 2023 appraisal.	Koch S et al.	—	2023	→
Comparisons of clinical characteristics, prognosis, epidemiological factors, and genetic susceptibility between HER2-low and HER2-zero breast cancer among Chinese females.	Zheng L et al.	—	2023	→
Development and testing of a polygenic risk score for breast cancer aggressiveness.	Shieh Y et al.	—	2023	→
Development of a Breast Cancer Risk Prediction Model Incorporating Polygenic Risk Scores and Nongenetic Risk Factors for Korean Women.	Choi J et al.	—	2023	→
Evaluation of SNPs associated with mammographic density in European women with mammographic density in Asian women from South-East Asia.	Mariapun S et al.	—	2023	→
Evaluation of the Association between <i>FGFR2</i> Gene Polymorphisms and Breast Cancer Risk in the Bangladeshi Population.	Jahan N et al.	—	2023	→
Genome-wide Association Study of Bladder Cancer Reveals New Biological and Translational Insights.	Koutros S et al.	—	2023	→
Integration of a Cross-Ancestry Polygenic Model With Clinical Risk Factors Improves Breast Cancer Risk Stratification.	Tshiaba PT et al.	—	2023	→
In vitro Anti-malignant Property of PCMT1 Silencing and Identification of the SNHG16/miR-195/PCMT1 Regulatory Axis in Breast Cancer Cells.	Zhang Z et al.	—	2023	→
Machine learning reveals genetic modifiers of the immune microenvironment of cancer.	Riley-Gillis B et al.	—	2023	→
Polymorphisms in genes of melatonin biosynthesis and signaling support the light-at-night hypothesis for breast cancer.	Wichert K et al.	—	2023	→
Potential Role of Zinc Finger 365 <i>rs10822013</i> and <i>rs10995190</i> in Mammographic Density, Sporadic Breast Cancer Risk, and Prognosis.	Ghadamgahi SR et al.	—	2023	→
Prediction of breast cancer risk for sisters of women attending screening.	Mao X et al.	—	2023	→
Single nucleotide polymorphisms associated with female breast cancer susceptibility in Chinese population.	Jia Z et al.	—	2023	→
Susceptibility Genes Associated with Multiple Primary Cancers.	Lu M et al.	—	2023	→
Update Breast Cancer 2023 Part 1 - Early Stage Breast Cancer.	Hartkopf AD et al.	—	2023	→
Validation of a breast cancer risk prediction model based on the key risk factors: family history, mammographic density and polygenic risk.	Allman R et al.	—	2023	→
Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study.	Morales Berstein F et al.	—	2022	→
Association between dried fruit intake and pan-cancers incidence risk: A two-sample Mendelian randomization study.	Jin C et al.	—	2022	→
Association of CYP2C19 Polymorphism With Proton Pump Inhibitors Effectiveness and With Fractures in Real-Life: Retrospective Cohort Study.	Gronich N et al.	—	2022	→
Association of <i>Hypoxia-Inducible Factor 1α</i> Gene Polymorphisms With Breast Cancer Susceptibility: A Meta-Analysis.	Islam MS et al.	—	2022	→
Associations between circulating proteins and risk of breast cancer by intrinsic subtypes: a Mendelian randomisation analysis.	Shu X et al.	—	2022	→
Associations of genetically proxied inhibition of HMG-CoA reductase, NPC1L1, and PCSK9 with breast cancer and prostate cancer.	Sun L et al.	—	2022	→
Associations of genetic susceptibility to 16 cancers with risk of breast cancer overall and by intrinsic subtypes.	Choi J et al.	—	2022	→
A Swedish Genome-Wide Haplotype Association Analysis Identifies a Novel Breast Cancer Susceptibility Locus in 8p21.2 and Characterizes Three Loci on Chromosomes 10, 11 and 16.	Barnekow E et al.	—	2022	→
Bone mineral density and risk of breast cancer: A cohort study and Mendelian randomization analysis.	Zhang Y et al.	—	2022	→
Combined Interaction of Cellular and Extracellular Components Causes Genetic Cascade Activation in Breast Cancer Metastasis.	Chauhan D et al.	—	2022	→
Common Variant in ALDH2 Modifies the Risk of Breast Cancer Among Carriers of the p.K3326* Variant in BRCA2.	Kluźniak W et al.	—	2022	→
Common variants in breast cancer risk loci predispose to distinct tumor subtypes.	Ahearn TU et al.	—	2022	→
Considering hormone-sensitive cancers as a single disease in the UK biobank reveals shared aetiology.	Ahmed M et al.	—	2022	→
Detection of germline variants in Brazilian breast cancer patients using multigene panel testing.	Guindalini RSC et al.	—	2022	→
ELSSI: parallel SNP-SNP interactions detection by ensemble multi-type detectors.	Wang X et al.	—	2022	→
Embryonic Programs in Cancer and Metastasis-Insights From the Mammary Gland.	Lee MY	—	2022	→
EpiHNet: Detecting epistasis by heterogeneous molecule network.	Wang X et al.	—	2022	→
Exploring the effects of genetic variation on gene regulation in cancer in the context of 3D genome structure.	Osman N et al.	—	2022	→
Feasibility of personalized screening and prevention recommendations in the general population through breast cancer risk assessment: results from a dedicated risk clinic.	Saghatchian M et al.	—	2022	→
Functional annotation of breast cancer risk loci: current progress and future directions.	Romualdo Cardoso S et al.	—	2022	→
Genome-wide interaction analysis of menopausal hormone therapy use and breast cancer risk among 62,370 women.	Wang X et al.	—	2022	→
HDAC Inhibitor Sodium Butyrate Attenuates the DNA Repair in Transformed but Not in Normal Fibroblasts.	Gnedina OO et al.	—	2022	→
Identifying and correcting for misspecifications in GWAS summary statistics and polygenic scores.	Privé F et al.	—	2022	→
Identifying and ranking causal biochemical biomarkers for breast cancer: a Mendelian randomisation study.	Tang SN et al.	—	2022	→
Inherited human Apollo deficiency causes severe bone marrow failure and developmental defects.	Kermasson L et al.	—	2022	→
Long noncoding RNA CCAT2 reduces chemosensitivity to 5-fluorouracil in breast cancer cells by activating the mTOR axis.	Zhou D et al.	—	2022	→
Mendelian Randomization and GWAS Meta Analysis Revealed the Risk-Increasing Effect of Schizophrenia on Cancers.	Yuan K et al.	—	2022	→
MiR-556-5p modulates migration, invasion, and epithelial-mesenchymal transition in breast cancer cells via targeting PTHrP.	Zhou R et al.	—	2022	→
MiRNA-363-3p/DUSP10/JNK axis mediates chemoresistance by enhancing DNA damage repair in diffuse large B-cell lymphoma.	Zhou W et al.	—	2022	→
Pathogenic Variant Spectrum in Breast Cancer Risk Genes in Finnish Patients.	Nurmi AK et al.	—	2022	→
PAX9 in Cancer Development.	Chen X et al.	—	2022	→
Pleiotropic <i>MLLT10</i> variation confers risk of meningioma and estrogen-mediated cancers.	Walsh KM et al.	—	2022	→
Polygenic risk scores for prediction of breast cancer risk in Asian populations.	Ho WK et al.	—	2022	→
Principles of molecular testing for hereditary cancer.	Mighton C et al.	—	2022	→
Rare germline copy number variants (CNVs) and breast cancer risk.	Dennis J et al.	—	2022	→
Recent Advances in Cancer Drug Discovery Through the Use of Phenotypic Reporter Systems, Connectivity Mapping, and Pooled CRISPR Screening.	Salame N et al.	—	2022	→
SNP-Target Genes Interaction Perturbing the Cancer Risk in the Post-GWAS.	Yang W et al.	—	2022	→
Somatic mutational profiles and germline polygenic risk scores in human cancer.	Liu Y et al.	—	2022	→
State-of-the-Art Fluorescent Probes: Duplex-Specific Nuclease-Based Strategies for Early Disease Diagnostics.	Ashraf G et al.	—	2022	→
The African Female Breast Cancer Epidemiology Study Protocol.	Ezeome ER et al.	—	2022	→
The current status of risk-stratified breast screening.	Clift AK et al.	—	2022	→
The risk variant rs11836367 contributes to breast cancer onset and metastasis by attenuating Wnt signaling via regulating <i>NTN4</i> expression.	Yang H et al.	—	2022	→
The Role of FTO in Tumors and Its Research Progress.	Wei H et al.	—	2022	→
The role of MTNR1B polymorphism on circadian rhythm-related cancer: A UK Biobank cohort study.	Wu J et al.	—	2022	→
TIGAR-V2: Efficient TWAS tool with nonparametric Bayesian eQTL weights of 49 tissue types from GTEx V8.	Parrish RL et al.	—	2022	→
Two distinct mechanisms underlie estrogen-receptor-negative breast cancer susceptibility at the 2p23.2 locus.	Mendoza-Fandiño G et al.	—	2022	→
Uncovering the Contribution of Moderate-Penetrance Susceptibility Genes to Breast Cancer by Whole-Exome Sequencing and Targeted Enrichment Sequencing of Candidate Genes in Women of European Ancestry.	Dumont M et al.	—	2022	→
A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers.	Coignard J et al.	—	2021	→
A functionally impaired missense variant identified in French Canadian families implicates FANCI as a candidate ovarian cancer-predisposing gene.	Fierheller CT et al.	—	2021	→
A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family.	Baddock HT et al.	—	2021	→
Application of Multilayer Evidence for Annotation of C-Terminal <i>BRCA2</i> Variants.	Butz H et al.	—	2021	→
Association between SNP rs527616 in lncRNA AQP4-AS1 and susceptibility to breast cancer in a southern Brazilian population.	Marchi RD et al.	—	2021	→
Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment.	Morra A et al.	—	2021	→
Cancer health disparities in racial/ethnic minorities in the United States.	Zavala VA et al.	—	2021	→
Characterization of Hepatitis B Virus Integrations Identified in Hepatocellular Carcinoma Genomes.	Mathkar PP et al.	—	2021	→
Characterization of intermediate-sized insertions using whole-genome sequencing data and analysis of their functional impact on gene expression.	Ashouri S et al.	—	2021	→
Circulating carotenoids and breast cancer among high-risk individuals.	Peng C et al.	—	2021	→
Combination of a 15-SNP Polygenic Risk Score and Classical Risk Factors for the Prediction of Breast Cancer Risk in Cypriot Women.	Yiangou K et al.	—	2021	→
Combined Associations of a Polygenic Risk Score and Classical Risk Factors With Breast Cancer Risk.	Kapoor PM et al.	—	2021	→
CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers.	Johnson N et al.	—	2021	→
DeCompress: tissue compartment deconvolution of targeted mRNA expression panels using compressed sensing.	Bhattacharya A et al.	—	2021	→
Elevated risk thresholds predict endocrine risk-reducing medication use in the Athena screening registry.	Huilgol YS et al.	—	2021	→
Fine-mapping of two differentiated thyroid carcinoma susceptibility loci at 2q35 and 8p12 in Europeans, Melanesians and Polynesians.	Guibon J et al.	—	2021	→
From <i>BRCA1</i> to Polygenic Risk Scores: Mutation-Associated Risks in Breast Cancer-Related Genes.	Woodward ER et al.	—	2021	→
Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element.	Baxter JS et al.	—	2021	→
Functional Screenings Identify Regulatory Variants Associated with Breast Cancer Susceptibility.	Ren N et al.	—	2021	→
Gene- and pathway-level analyses of iCOGS variants highlight novel signaling pathways underlying familial breast cancer susceptibility.	Lonjou C et al.	—	2021	→
Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies?	Park J et al.	—	2021	→
Genetic modifiers regulating DNA replication and double-strand break repair are associated with differences in mammary tumors in mouse models of Li-Fraumeni syndrome.	Majhi PD et al.	—	2021	→
Genetic Predictors of Chemotherapy-Induced Peripheral Neuropathy from Paclitaxel, Carboplatin and Oxaliplatin: NCCTG/Alliance N08C1, N08CA and N08CB Study.	Adjei AA et al.	—	2021	→
Genetic Variations and Health-Related Quality of Life (HRQOL): A Genome-Wide Study Approach.	Adjei AA et al.	—	2021	→
Genomic risk prediction of coronary artery disease in women with breast cancer: a prospective cohort study.	Liou L et al.	—	2021	→
<i>Alu</i> insertion variants alter gene transcript levels.	Payer LM et al.	—	2021	→
Influence of Family History of Breast or Ovarian Cancer on Pathological Complete Response and Long-Term Prognosis in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy.	Wunderle M et al.	—	2021	→
Ischemic stroke and myocardial ischemia in clopidogrel users and the association with CYP2C19 loss-of-function homozygocity: a real-world study.	Gronich N et al.	—	2021	→
Is Mammographic Breast Density an Endophenotype for Breast Cancer?	Darcey E et al.	—	2021	→
Lipids, Anthropometric Measures, Smoking and Physical Activity Mediate the Causal Pathway From Education to Breast Cancer in Women: A Mendelian Randomization Study.	Li H et al.	—	2021	→
Lymph node metastases in breast cancer: Investigating associations with tumor characteristics, molecular subtypes and polygenic risk score using a continuous growth model.	Isheden G et al.	—	2021	→
Mammographic features are associated with cardiometabolic disease risk and mortality.	Grassmann F et al.	—	2021	→
Mendelian randomisation study of smoking exposure in relation to breast cancer risk.	Park HA et al.	—	2021	→
MOSTWAS: Multi-Omic Strategies for Transcriptome-Wide Association Studies.	Bhattacharya A et al.	—	2021	→
Performance of Breast Cancer Polygenic Risk Scores in 760 Female CHEK2 Germline Mutation Carriers.	Borde J et al.	—	2021	→
Polygenic hazard score is associated with prostate cancer in multi-ethnic populations.	Huynh-Le MP et al.	—	2021	→
Population-Based Estimates of the Age-Specific Cumulative Risk of Breast Cancer for Pathogenic Variants in <i>CHEK2</i>: Findings from the Australian Breast Cancer Family Registry.	Nguyen-Dumont T et al.	—	2021	→
Risk assessment and genetic counseling for hereditary breast and ovarian cancer syndromes-Practice resource of the National Society of Genetic Counselors.	Berliner JL et al.	—	2021	→
Risks and Function of Breast Cancer Susceptibility Alleles.	Torabi Dalivandan S et al.	—	2021	→
Systematic evaluation of the effect of polyadenylation signal variants on the expression of disease-associated genes.	Chen M et al.	—	2021	→
The predictive ability of the 313 variant-based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant.	Lakeman IMM et al.	—	2021	→
The rs9340799 polymorphism of the estrogen receptor alpha (ESR1) gene and its association with breast cancer susceptibility.	Tan SC et al.	—	2021	→
Update Breast Cancer 2021 Part 1 - Prevention and Early Stages.	Stickeler E et al.	—	2021	→
ABC-GWAS: Functional Annotation of Estrogen Receptor-Positive Breast Cancer Genetic Variants.	Manjunath M et al.	—	2020	→
A framework for transcriptome-wide association studies in breast cancer in diverse study populations.	Bhattacharya A et al.	—	2020	→
A Genetic Risk Score to Personalize Prostate Cancer Screening, Applied to Population Data.	Huynh-Le MP et al.	—	2020	→
Allele-specific miRNA-binding analysis identifies candidate target genes for breast cancer risk.	Jacinta-Fernandes A et al.	—	2020	→
A Mendelian randomization analysis of circulating lipid traits and breast cancer risk.	Beeghly-Fadiel A et al.	—	2020	→
A network analysis to identify mediators of germline-driven differences in breast cancer prognosis.	Escala-Garcia M et al.	—	2020	→
An integrative multi-omics network-based approach identifies key regulators for breast cancer.	Chen YX et al.	—	2020	→
A Polygenic Risk Score for Breast Cancer in US Latinas and Latin American Women.	Shieh Y et al.	—	2020	→
Applications of Next Generation Sequencing to the Analysis of Familial Breast/Ovarian Cancer.	Zelli V et al.	—	2020	→
Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk, in the Breast Cancer Association Consortium.	Kapoor PM et al.	—	2020	→
Association of matrix metalloproteinases 3 and 9 single nucleotide polymorphisms with breast cancer risk: A case-control study.	Abd Elmaogoud Ragab Ibrahim F et al.	—	2020	→
Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk.	Kramer I et al.	—	2020	→
Cancer PRSweb: An Online Repository with Polygenic Risk Scores for Major Cancer Traits and Their Evaluation in Two Independent Biobanks.	Fritsche LG et al.	—	2020	→
Candidate Causal Variants at the 8p12 Breast Cancer Risk Locus Regulate <i>DUSP4</i>.	Glubb DM et al.	—	2020	→
CDYL2 Epigenetically Regulates MIR124 to Control NF-κB/STAT3-Dependent Breast Cancer Cell Plasticity.	Siouda M et al.	—	2020	→
Clinical applications of polygenic breast cancer risk: a critical review and perspectives of an emerging field.	Yanes T et al.	—	2020	→
Clustering of known low and moderate risk alleles rather than a novel recessive high-risk gene in non-BRCA1/2 sib trios affected with breast cancer.	Hilbers FS et al.	—	2020	→
Combination of phenotype and polygenic risk score in breast cancer risk evaluation in the Spanish population: a case -control study.	Triviño JC et al.	—	2020	→
Critical Analysis of Genome-Wide Association Studies: Triple Negative Breast Cancer <i>Quae Exempli Causa</i>.	Jurj MA et al.	—	2020	→
Development and Validation of a Clinical Polygenic Risk Score to Predict Breast Cancer Risk.	Hughes E et al.	—	2020	→
Discovery of rare coding variants in OGDHL and BRCA2 in relation to breast cancer risk in Chinese women.	Guo X et al.	—	2020	→
DNA methylation level in blood and relations to breast cancer, risk factors and environmental exposure in Greenlandic Inuit women.	Wielsøe M et al.	—	2020	→
DOT: Gene-set analysis by combining decorrelated association statistics.	Vsevolozhskaya OA et al.	—	2020	→
DualWMDR: Detecting epistatic interaction with dual screening and multifactor dimensionality reduction.	Cao X et al.	—	2020	→
European polygenic risk score for prediction of breast cancer shows similar performance in Asian women.	Ho WK et al.	—	2020	→
Evaluation of associations between genetically predicted circulating protein biomarkers and breast cancer risk.	Shu X et al.	—	2020	→
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes.	Fachal L et al.	—	2020	→
Fine-mapping of a novel premenopausal breast cancer susceptibility locus at Chr4q31.22 in Caucasian women and validation in African and Chinese women.	Kumaran M et al.	—	2020	→
Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses.	Zhang H et al.	—	2020	→
Hyperthyroidism is associated with breast cancer risk and mammographic and genetic risk predictors.	Yang H et al.	—	2020	→
<i>Cis</i>- and <i>Trans</i>-Acting Expression Quantitative Trait Loci of Long Non-Coding RNA in 2,549 Cancers With Potential Clinical and Therapeutic Implications.	Li W et al.	—	2020	→
Identification and genomic analysis of pedigrees with exceptional longevity identifies candidate rare variants.	Miller JB et al.	—	2020	→
Identification of Novel Loci and New Risk Variant in Known Loci for Colorectal Cancer Risk in East Asians.	Lu Y et al.	—	2020	→
Integrative genomic analysis implicates ERCC6 and its interaction with ERCC8 in susceptibility to breast cancer.	Moslehi R et al.	—	2020	→
Leveraging effect size distributions to improve polygenic risk scores derived from summary statistics of genome-wide association studies.	Song S et al.	—	2020	→
Nonmalignant Formalin-Fixed Paraffin-Embedded Tissues as a Source to Study Germline Variants and Cancer Predisposition: A Systematic Review.	Youssef O et al.	—	2020	→
Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts.	Rashkin SR et al.	—	2020	→
Pathogenic Germline DNA Repair Gene and <i>HOXB13</i> Mutations in Men With Metastatic Prostate Cancer.	Boyle JL et al.	—	2020	→
Pathway-Affecting Single Nucleotide Polymorphisms (SNPs) in RPS6KA1 and MBIP Genes are Associated with Breast Cancer Risk.	Shareefi G et al.	—	2020	→
Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis.	Papadimitriou N et al.	—	2020	→
SNPs in lncRNA Regions and Breast Cancer Risk.	Suvanto M et al.	—	2020	→
Supervariants identification for breast cancer.	Hu J et al.	—	2020	→
The association of single nucleotide polymorphisms (SNPs) with breast density and breast cancer survival: the Malmö Diet and Cancer Study.	Sartor H et al.	—	2020	→
The Contribution of Genetic Variants to the Risk of Papillary Thyroid Carcinoma in the Kazakh Population: Study of Common Single Nucleotide Polymorphisms and Their Clinicopathological Correlations.	Mussazhanova Z et al.	—	2020	→
The emerging field of polygenic risk scores and perspective for use in clinical care.	Yanes T et al.	—	2020	→
Trans-ethnic meta-analysis of genome-wide association studies identifies maternal ITPR1 as a novel locus influencing fetal growth during sensitive periods in pregnancy.	Tekola-Ayele F et al.	—	2020	→
Treatment of Pediatric Glioblastoma with Combination Olaparib and Temozolomide Demonstrates 2-Year Durable Response.	Valiakhmetova A et al.	—	2020	→
Update Breast Cancer 2020 Part 1 - Early Breast Cancer: Consolidation of Knowledge About Known Therapies.	Schneeweiss A et al.	—	2020	→
Update Breast Cancer 2020 Part 3 - Early Breast Cancer.	Huober J et al.	—	2020	→
Using genetics to decipher the link between type 2 diabetes and cancer: shared aetiology or downstream consequence?	Vincent EE et al.	—	2020	→
AA genotype of cyclin D1 G870A polymorphism increases breast cancer risk: Findings of a case-control study and meta-analysis.	Akhter N et al.	—	2019	→
A functional single nucleotide polymorphism in ABCC11, rs17822931, is associated with the risk of breast cancer in Japanese.	Ishiguro J et al.	—	2019	→
An exome-wide rare variant analysis of Korean men identifies three novel genes predisposing to prostate cancer.	Oh JJ et al.	—	2019	→
Antitumor effects of arsenic disulfide on the viability, migratory ability, apoptosis and autophagy of breast cancer cells.	Zhao Y et al.	—	2019	→
Association between mitochondrial genetic variation and breast cancer risk: The Multiethnic Cohort.	Li Y et al.	—	2019	→
Association of CYP1A1 M2 (A2455G) Polymorphism with Susceptibility to Breast Cancer in Mazandaran Province, Northern Iran: A Case-control Study.	Khalili-Tanha G et al.	—	2019	→
Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis.	Shu X et al.	—	2019	→
Cancer-Associated Intermediate Conductance Ca<sup>2+</sup>-Activated K⁺ Channel K<sub>Ca</sub>3.1.	Mohr CJ et al.	—	2019	→
Characteristics and utilisation of the Mayo Clinic Biobank, a clinic-based prospective collection in the USA: cohort profile.	Olson JE et al.	—	2019	→
Deep Learning: Current and Emerging Applications in Medicine and Technology.	Akay A et al.	—	2019	→
Development and pilot testing of a leaflet informing women with breast cancer about genomic testing for polygenic risk.	Kaur R et al.	—	2019	→
Discovery of common and rare genetic risk variants for colorectal cancer.	Huyghe JR et al.	—	2019	→
Ductal Carcinoma in Situ Biomarkers in a Precision Medicine Era: Current and Future Molecular-Based Testing.	Shee K et al.	—	2019	→
Evaluation of significant genome-wide association studies risk - SNPs in young breast cancer patients.	Rath M et al.	—	2019	→
Fast and accurate genomic analyses using genome graphs.	Rakocevic G et al.	—	2019	→
Functional Analysis of Promoter Variants in Genes Involved in Sex Steroid Action, DNA Repair and Cell Cycle Control.	Hamdi Y et al.	—	2019	→
Genetic associations of breast and prostate cancer are enriched for regulatory elements identified in disease-related tissues.	Chen H et al.	—	2019	→
Genetic Epidemiology of Breast Cancer in Latin America.	Zavala VA et al.	—	2019	→
Genetic susceptibility to radiation-induced breast cancer after Hodgkin lymphoma.	Opstal-van Winden AWJ et al.	—	2019	→
Genetic variants of genes in the NER pathway associated with risk of breast cancer: A large-scale analysis of 14 published GWAS datasets in the DRIVE study.	Ge J et al.	—	2019	→
Genetic Variation in Steroid and Xenobiotic Metabolizing Pathways and Enterolactone Excretion Before and After Flaxseed Intervention in African American and European American Women.	Chang H et al.	—	2019	→
Genetic Variations and Precision Medicine.	Alzu'bi AA et al.	—	2019	→
Genetic variations within alternative splicing associated genes are associated with breast cancer susceptibility in Chinese women.	Xu X et al.	—	2019	→
Genomics applied to the treatment of breast cancer.	Hamdan D et al.	—	2019	→
Germline BRCA2 K3326X and CHEK2 I157T mutations increase risk for sporadic pancreatic ductal adenocarcinoma.	Obazee O et al.	—	2019	→
Germline variants in cancer genes in high-risk non-BRCA patients from Puerto Rico.	Dutil J et al.	—	2019	→
Graphene Oxide-Based Targeting of Extracellular Cathepsin D and Cathepsin L As A Novel Anti-Metastatic Enzyme Cancer Therapy.	Tabish TA et al.	—	2019	→
Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study.	Qian F et al.	—	2019	→
High-risk women's risk perception after receiving personalized polygenic breast cancer risk information.	Forrest LE et al.	—	2019	→
HiSSI: high-order SNP-SNP interactions detection based on efficient significant pattern and differential evolution.	Cao X et al.	—	2019	→
Identification of novel common breast cancer risk variants at the 6q25 locus among Latinas.	Hoffman J et al.	—	2019	→
Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population.	Low SK et al.	—	2019	→
Identifying breast cancer susceptibility genes - a review of the genetic background in familial breast cancer.	Wendt C et al.	—	2019	→
Interaction between genetic ancestry and common breast cancer susceptibility variants in Colombian women.	Torres D et al.	—	2019	→
Interval breast cancer is associated with other types of tumors.	Grassmann F et al.	—	2019	→
Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk.	Vachon CM et al.	—	2019	→
Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer.	Lu Y et al.	—	2019	→
Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification.	Parsons MT et al.	—	2019	→
LncRNA EGOT Promotes Tumorigenesis Via Hedgehog Pathway in Gastric Cancer.	Peng W et al.	—	2019	→
<i>BARD1</i> is A Low/Moderate Breast Cancer Risk Gene: Evidence Based on An Association Study of the Central European p.Q564X Recurrent Mutation.	Suszynska M et al.	—	2019	→
Mapping Mammary Tumor Traits in the Rat.	Flister MJ et al.	—	2019	→
Pan-Cancer Study Detects Novel Genetic Risk Variants and Shared Genetic Basis in Two Large Cohorts	Rashkin SR et al.	—	2019	—
Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.	Mavaddat N et al.	—	2019	→
Precision medicine in resistant Tuberculosis: Treat the correct patient, at the correct time, with the correct drug.	Mahomed S et al.	—	2019	→
Prediagnosis aspirin use, DNA methylation, and mortality after breast cancer: A population-based study.	Wang T et al.	—	2019	→
Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort.	Li J et al.	—	2019	→
Re-evaluating genetic variants identified in candidate gene studies of breast cancer risk using data from nearly 280,000 women of Asian and European ancestry.	Yang Y et al.	—	2019	→
Relationship between West African ancestry with lung cancer risk and survival in African Americans.	Mitchell KA et al.	—	2019	→
Statistical methods for genome-wide association studies.	Wang MH et al.	—	2019	→
Systematic analysis and prediction model construction of alternative splicing events in hepatocellular carcinoma: a study on the basis of large-scale spliceseq data from The Cancer Genome Atlas.	Yang L et al.	—	2019	→
Systematic evaluation of cancer-specific genetic risk score for 11 types of cancer in The Cancer Genome Atlas and Electronic Medical Records and Genomics cohorts.	Shi Z et al.	—	2019	→
The Cancer-Associated Genetic Variant Rs3903072 Modulates Immune Cells in the Tumor Microenvironment.	Zhang Y et al.	—	2019	→
The functional ALDH2 polymorphism is associated with breast cancer risk: A pooled analysis from the Breast Cancer Association Consortium.	Ugai T et al.	—	2019	→
The genetic interplay between body mass index, breast size and breast cancer risk: a Mendelian randomization analysis.	Ooi BNS et al.	—	2019	→
The impact of exercise on growth factors (VEGF and FGF2): results from a 12-month randomized intervention trial.	Brenner DR et al.	—	2019	→
Towards a more precise and individualized assessment of breast cancer risk.	Wood ME et al.	—	2019	→
Transforming growth factor beta receptor II (TGFBR2) promoter region polymorphism in Brazilian breast cancer patients: association with susceptibility, clinicopathological features, and interaction with TGFB1 haplotypes.	Vitiello GAF et al.	—	2019	→
Translational highlights in breast cancer research and treatment: recent developments with clinical impact.	Fasching PA et al.	—	2019	→
Update Breast Cancer 2019 Part 1 - Implementation of Study Results of Novel Study Designs in Clinical Practice in Patients with Early Breast Cancer.	Hartkopf AD et al.	—	2019	→
Update Breast Cancer 2019 Part 3 - Current Developments in Early Breast Cancer: Review and Critical Assessment by an International Expert Panel.	Kolberg HC et al.	—	2019	→
Update Breast Cancer 2019 Part 4 - Diagnostic and Therapeutic Challenges of New, Personalised Therapies for Patients with Early Breast Cancer.	Schütz F et al.	—	2019	→
A comprehensive analysis of polymorphic variants in steroid hormone and insulin-like growth factor-1 metabolism and risk of in situ breast cancer: Results from the Breast and Prostate Cancer Cohort Consortium.	Barrdahl M et al.	—	2018	→
A Comprehensive cis-eQTL Analysis Revealed Target Genes in Breast Cancer Susceptibility Loci Identified in Genome-wide Association Studies.	Guo X et al.	—	2018	→
Addition of a polygenic risk score, mammographic density, and endogenous hormones to existing breast cancer risk prediction models: A nested case-control study.	Zhang X et al.	—	2018	→
Adipose tissue levels of polybrominated diphenyl ethers and breast cancer risk in Chinese women: A case-control study.	He Y et al.	—	2018	→
Age exerts a continuous effect in the outcomes of Asian breast cancer patients treated with breast-conserving therapy.	Wong FY et al.	—	2018	→
A genome wide SNP genotyping study in the Tunisian population: specific reporting on a subset of common breast cancer risk loci.	Hamdi Y et al.	—	2018	→
Applications of RNA Indexes for Precision Oncology in Breast Cancer.	Ma L et al.	—	2018	→
Association of BRCA2 K3326* With Small Cell Lung Cancer and Squamous Cell Cancer of the Skin.	Rafnar T et al.	—	2018	→
Association of Cell-Free DNA Tumor Fraction and Somatic Copy Number Alterations With Survival in Metastatic Triple-Negative Breast Cancer.	Stover DG et al.	—	2018	→
A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer.	Wu L et al.	—	2018	→
BAG3 Overexpression and Cytoprotective Autophagy Mediate Apoptosis Resistance in Chemoresistant Breast Cancer Cells.	Das CK et al.	—	2018	→
BRCA1/2 mutations are not a common cause of malignant melanoma in the Polish population.	Dębniak T et al.	—	2018	→
BRCA1/2-negative, high-risk breast cancers (BRCAX) for Asian women: genetic susceptibility loci and their potential impacts.	Lee JY et al.	—	2018	→
BRCA1 and BRCA2 germline variants in breast cancer patients from the Republic of Macedonia.	Jakimovska M et al.	—	2018	→
Breast cancer associated germline structural variants harboring small noncoding RNAs impact post-transcriptional gene regulation.	Kumaran M et al.	—	2018	→
Breast Cancer Family History and Contralateral Breast Cancer Risk in Young Women: An Update From the Women's Environmental Cancer and Radiation Epidemiology Study.	Reiner AS et al.	—	2018	→
Breast Cancer Risk Model Requirements for Counseling, Prevention, and Screening.	Gail MH et al.	—	2018	→
Breast cancer screening in young women.	Desreux JAC	—	2018	→
Bridging the gap by discerning SNPs in linkage disequilibrium and their role in breast cancer.	Maqbool SN et al.	—	2018	→
Cancer genetics, precision prevention and a call to action.	Turnbull C et al.	—	2018	→
Capture Hi-C identifies putative target genes at 33 breast cancer risk loci.	Baxter JS et al.	—	2018	→
ClusterMI: Detecting High-Order SNP Interactions Based on Clustering and Mutual Information.	Cao X et al.	—	2018	→
Cohort Profile: The Singapore Multi-Ethnic Cohort (MEC) study.	Tan KHX et al.	—	2018	→
Common Genetic Variation and Breast Cancer Risk-Past, Present, and Future.	Lilyquist J et al.	—	2018	→
Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer.	Wittkowski KM et al.	—	2018	→
Cumulative evidence for relationships between multiple variants in the VTI1A and TCF7L2 genes and cancer incidence.	Zhang M et al.	—	2018	→
Differential Burden of Rare and Common Variants on Tumor Characteristics, Survival, and Mode of Detection in Breast Cancer.	Li J et al.	—	2018	→
Downregulated GBX2 gene suppresses proliferation, invasion and angiogenesis of breast cancer cells through inhibiting the Wnt/β-catenin signaling pathway.	Fang Y et al.	—	2018	→
Elucidating the Underlying Functional Mechanisms of Breast Cancer Susceptibility Through Post-GWAS Analyses.	Rivandi M et al.	—	2018	→
Ensemble learning for detecting gene-gene interactions in colorectal cancer.	Dorani F et al.	—	2018	→
Epidemiology of Moderate Alcohol Consumption and Breast Cancer: Association or Causation?	Zakhari S et al.	—	2018	→
Ept7, a quantitative trait locus that controls estrogen-induced pituitary lactotroph hyperplasia in rat, is orthologous to a locus in humans that has been associated with numerous cancer types and common diseases.	Dennison KL et al.	—	2018	→
Evaluating the breast cancer predisposition role of rare variants in genes associated with low-penetrance breast cancer risk SNPs.	Li N et al.	—	2018	→
Evaluation of 4-bp insertion/deletion polymorphism within the 3'UTR of SGSM3 in bladder cancer using mismatch PCR-RFLP method: A preliminary report.	Hashemi M et al.	—	2018	→
Evaluation of three polygenic risk score models for the prediction of breast cancer risk in Singapore Chinese.	Chan CHT et al.	—	2018	→
Genetic determinants of sporadic breast cancer in Sri Lankan women.	Sirisena ND et al.	—	2018	→
Genetic Evidence for the Association between Schizophrenia and Breast Cancer.	Shi J et al.	—	2018	→
Genetic Modifiers of the Breast Tumor Microenvironment.	Flister MJ et al.	—	2018	→
Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses.	Painter JN et al.	—	2018	→
Genetic variants demonstrating flip-flop phenomenon and breast cancer risk prediction among women of African ancestry.	Wang S et al.	—	2018	→
Genetic variation in sensitivity to estrogens and breast cancer risk.	Jerry DJ et al.	—	2018	→
Genetic Variations, Exposure to Persistent Organic Pollutants and Breast Cancer Risk - A Greenlandic Case-Control Study.	Wielsøe M et al.	—	2018	→
Genome-Wide Association Studies in Glioma.	Kinnersley B et al.	—	2018	→
Genome-Wide Association Studies of Cancer in Diverse Populations.	Park SL et al.	—	2018	→
Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer.	Klein AP et al.	—	2018	→
Genomic Analysis Using Regularized Regression in High-Grade Serous Ovarian Cancer.	Natanzon Y et al.	—	2018	→
Germline Variation and Breast Cancer Incidence: A Gene-Based Association Study and Whole-Genome Prediction of Early-Onset Breast Cancer.	Scannell Bryan M et al.	—	2018	→
Identification of shared genetic variants between schizophrenia and lung cancer.	Zuber V et al.	—	2018	→
Importance of genetic background of oxysterol signaling in cancer.	Holy P et al.	—	2018	→
Inherited factors contribute to an inverse association between preeclampsia and breast cancer.	Yang H et al.	—	2018	→
Inherited mutations in <i>BRCA1</i> and <i>BRCA2</i> in an unselected multiethnic cohort of Asian patients with breast cancer and healthy controls from Malaysia.	Wen WX et al.	—	2018	→
Integrated analysis of long noncoding RNA and mRNA expression profiles reveals the potential role of long noncoding RNA in different bovine lactation stages.	Zheng X et al.	—	2018	→
Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium.	Rudolph A et al.	—	2018	→
Long-term exposure to insulin and volumetric mammographic density: observational and genetic associations in the Karma study.	Borgquist S et al.	—	2018	→
Making Sense of SNPs: Women's Understanding and Experiences of Receiving a Personalized Profile of Their Breast Cancer Risks.	Young MA et al.	—	2018	→
Mental health, loneliness, and illness perception outcomes in quality of life among young breast cancer patients after mastectomy: the role of breast reconstruction.	Fanakidou I et al.	—	2018	→
microRNA-98 inhibits the proliferation, invasion, migration and promotes apoptosis of breast cancer cells by binding to HMGA2.	Wang MJ et al.	—	2018	→
MMP8 and MMP9 gene polymorphisms were associated with breast cancer risk in a Chinese Han population.	Wang K et al.	—	2018	→
Modulation of oncogenic transcription factors by bioactive natural products in breast cancer.	Hasanpourghadi M et al.	—	2018	→
Multi-gene Panel Testing in Breast Cancer Management.	Fountzilas C et al.	—	2018	→
Mutational Analysis of Oncogenic AKT1 Gene Associated with Breast Cancer Risk in the High Altitude Ecuadorian Mestizo Population.	López-Cortés A et al.	—	2018	→
No evidence for association of <i>MTHFR</i> 677C>T and 1298A>C variants with placental DNA methylation.	Del Gobbo GF et al.	—	2018	→
Non-Coding Variants in <i>BRCA1</i> and <i>BRCA2</i> Genes: Potential Impact on Breast and Ovarian Cancer Predisposition.	Santana Dos Santos E et al.	—	2018	→
Nutrient Sensing, Signaling and Ageing: The Role of IGF-1 and mTOR in Ageing and Age-Related Disease.	Johnson SC	—	2018	→
Obligatory and facilitative allelic variation in the DNA methylome within common disease-associated loci.	Bell CG et al.	—	2018	→
Personalised screening: is this the way forward?	Gilbert FJ et al.	—	2018	→
Personalized prevention in high risk individuals: Managing hormones and beyond.	Evans DG et al.	—	2018	→
Predictive accuracy of combined genetic and environmental risk scores.	Dudbridge F et al.	—	2018	→
Profile of common prostate cancer risk variants in an unscreened Romanian population.	Iordache PD et al.	—	2018	→
Radiation biology and oncology in the genomic era.	Kerns SL et al.	—	2018	→
Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer.	Liu Y et al.	—	2018	→
Rat models of 17β-estradiol-induced mammary cancer reveal novel insights into breast cancer etiology and prevention.	Shull JD et al.	—	2018	→
Recursive Feature Elimination by Sensitivity Testing.	Escanilla NS et al.	—	2018	→
Risk, Prediction and Prevention of Hereditary Breast Cancer - Large-Scale Genomic Studies in Times of Big and Smart Data.	Wunderle M et al.	—	2018	→
Saliva samples as a source of DNA for high throughput genotyping: an acceptable and sufficient means in improvement of risk estimation throughout mammographic diagnostics.	Poehls UG et al.	—	2018	→
Signatures of Long-Term Balancing Selection in Human Genomes.	Bitarello BD et al.	—	2018	→
Significant association between ERCC2 and MTHR polymorphisms and breast cancer susceptibility in Moroccan population: genotype and haplotype analysis in a case-control study.	Hardi H et al.	—	2018	→
The association between differentially expressed micro RNAs in breast cancer cell lines and the micro RNA-205 gene polymorphism in breast cancer tissue.	Zhang J et al.	—	2018	→
The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity.	Colombo M et al.	—	2018	→
The significance of cholesterol and its metabolite, 27-hydroxycholesterol in breast cancer.	Nelson ER	—	2018	→
Transformation of Summary Statistics from Linear Mixed Model Association on All-or-None Traits to Odds Ratio.	Lloyd-Jones LR et al.	—	2018	→
Update Breast Cancer 2018 (Part 3) - Genomics, Individualized Medicine and Immune Therapies - in the Middle of a New Era: Prevention and Treatment Strategies for Early Breast Cancer.	Wöckel A et al.	—	2018	→
Use of Single-Nucleotide Polymorphisms and Mammographic Density Plus Classic Risk Factors for Breast Cancer Risk Prediction.	van Veen EM et al.	—	2018	→
Validating a breast cancer score in Spanish women. The MCC-Spain study.	Dierssen-Sotos T et al.	—	2018	→
Validation of a genetic risk score for Arkansas women of color.	Starlard-Davenport A et al.	—	2018	→
Validation of the novel susceptibility loci for prostate cancer in a Chinese population.	Wu Y et al.	—	2018	→
Vitamin D status and epigenetic-based mortality risk score: strong independent and joint prediction of all-cause mortality in a population-based cohort study.	Gao X et al.	—	2018	→
Addressing the challenges of applying precision oncology.	Shin SH et al.	—	2017	→
A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data.	Melloni GEM et al.	—	2017	→
A monograph proposing the use of canine mammary tumours as a model for the study of hereditary breast cancer susceptibility genes in humans.	Goebel K et al.	—	2017	→
Application of pharmacometrics and quantitative systems pharmacology to cancer therapy: The example of luminal a breast cancer.	Fleisher B et al.	—	2017	→
Assessment of Breast Cancer Risk Factors Reveals Subtype Heterogeneity.	Holm J et al.	—	2017	→
Association analysis identifies 65 new breast cancer risk loci.	Michailidou K et al.	—	2017	→
Association between breast cancer genetic susceptibility variants and terminal duct lobular unit involution of the breast.	Bodelon C et al.	—	2017	→
Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.	Telomeres Mendelian Randomization Collaboration et al.	—	2017	→
Association of breast adipose tissue levels of polychlorinated biphenyls and breast cancer development in women from Chaoshan, China.	He Y et al.	—	2017	→
Association of Common Genetic Variants With Contralateral Breast Cancer Risk in the WECARE Study.	Robson ME et al.	—	2017	→
Association of Genome-Wide Association Study (GWAS) Identified SNPs and Risk of Breast Cancer in an Indian Population.	Nagrani R et al.	—	2017	→
Association Study Confirmed Three Breast Cancer-Specific Molecular Subtype-Associated Susceptibility Loci in Chinese Han Women.	Xu Y et al.	—	2017	→
BaalChIP: Bayesian analysis of allele-specific transcription factor binding in cancer genomes.	de Santiago I et al.	—	2017	→
Biomarker Studies in Early Detection and Prognosis of Breast Cancer.	Li G et al.	—	2017	→
Blood pressure and risk of breast cancer, overall and by subtypes: a prospective cohort study.	Yang Y et al.	—	2017	→
BRCA1 and BRCA2 mutations and treatment strategies for breast cancer.	Godet I et al.	—	2017	→
Breast Cancer Risk Estimation and Personal Insurance: A Qualitative Study Presenting Perspectives from Canadian Patients and Decision Makers.	Dalpé G et al.	—	2017	→
Breast cancer risk prediction: an update to the Rosner-Colditz breast cancer incidence model.	Rice MS et al.	—	2017	→
Breast cancer risk prediction using a polygenic risk score in the familial setting: a prospective study from the Breast Cancer Family Registry and kConFab.	Li H et al.	—	2017	→
Breast Cancer Screening in the Precision Medicine Era: Risk-Based Screening in a Population-Based Trial.	Shieh Y et al.	—	2017	→
Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer.	Zuber V et al.	—	2017	→
Cancer risk susceptibility loci in a Swedish population.	Liu W et al.	—	2017	→
Cell signalling pathway regulation by RanBPM: molecular insights and disease implications.	Salemi LM et al.	—	2017	→
Characterizing Genetic Susceptibility to Breast Cancer in Women of African Ancestry.	Feng Y et al.	—	2017	→
CHST9 rs1436904 genetic variant contributes to prognosis of triple-negative breast cancer.	Yuan J et al.	—	2017	→
Cis-eQTL-based trans-ethnic meta-analysis reveals novel genes associated with breast cancer risk.	Hoffman JD et al.	—	2017	→
Cohort Profile: The Karolinska Mammography Project for Risk Prediction of Breast Cancer (KARMA).	Gabrielson M et al.	—	2017	→
Cohort Profile: The Melbourne Collaborative Cohort Study (Health 2020).	Milne RL et al.	—	2017	→
Common shared genetic variation behind decreased risk of breast cancer in celiac disease.	Ugalde-Morales E et al.	—	2017	→
Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas.	Huo D et al.	—	2017	→
Comparison of the association of mammographic density and clinical factors with ductal carcinoma in situ versus invasive ductal breast cancer in Korean women.	Ko H et al.	—	2017	→
Computational Analysis of Breast Cancer GWAS Loci Identifies the Putative Deleterious Effect of STXBP4 and ZNF404 Gene Variants.	Masoodi TA et al.	—	2017	→
Evaluating genetic variants associated with breast cancer risk in high and moderate-penetrance genes in Asians.	Han MR et al.	—	2017	→
Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers.	Kuchenbaecker KB et al.	—	2017	→
Expression Quantitative Trait loci (QTL) in tumor adjacent normal breast tissue and breast tumor tissue.	Quiroz-Zárate A et al.	—	2017	→
Fibroblast growth factor receptors in breast cancer.	Wang S et al.	—	2017	→
Functional classification of DNA variants by hybrid minigenes: Identification of 30 spliceogenic variants of BRCA2 exons 17 and 18.	Fraile-Bethencourt E et al.	—	2017	→
Functional germline variants as potential co-oncogenes.	Agarwal D et al.	—	2017	→
Genetic Breast Cancer Susceptibility Variants and Prognosis in the Prospectively Randomized SUCCESS A Study.	Hein A et al.	—	2017	→
Genetic Determinants of Breast Cancer Risk in Childhood Cancer Survivors.	Meier M et al.	—	2017	→
Genetic epidemiology of ovarian cancer and prospects for polygenic risk prediction.	Jones MR et al.	—	2017	→
Genetic modifiers of CHEK2*1100delC-associated breast cancer risk.	Muranen TA et al.	—	2017	→
Genetic variants at 9p21.3 are associated with risk of esophageal squamous cell carcinoma in a Chinese population.	Lin X et al.	—	2017	→
Genetic Variants in Epigenetic Pathways and Risks of Multiple Cancers in the GAME-ON Consortium.	Toth R et al.	—	2017	→
Genetic variants in long noncoding RNA <i>H19</i> contribute to the risk of breast cancer in a southeast China Han population.	Lin Y et al.	—	2017	→
Genetic variants of ESR1 and SGSM3 are associated with the susceptibility of breast cancer in the Chinese population.	Tan T et al.	—	2017	→
Genetic variants within the cancer susceptibility region 8q24 and ovarian cancer risk in Han Chinese women.	Han J et al.	—	2017	→
Genome-wide association studies of cancer: current insights and future perspectives.	Sud A et al.	—	2017	→
Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis.	Uimari O et al.	—	2017	→
Germline copy number variations are associated with breast cancer risk and prognosis.	Kumaran M et al.	—	2017	→
Germline variation in ADAMTSL1 is associated with prognosis following breast cancer treatment in young women.	Kadalayil L et al.	—	2017	→
Gynecologic cancer mortality in Trinidad and Tobago and comparisons of mortality-to-incidence rate ratios across global regions.	Llanos AAM et al.	—	2017	→
HiSeeker: Detecting High-Order SNP Interactions Based on Pairwise SNP Combinations.	Liu J et al.	—	2017	→
Identification of breast cancer associated variants that modulate transcription factor binding.	Liu Y et al.	—	2017	→
Identification of Novel Breast Cancer Risk Loci.	Chan CHT et al.	—	2017	→
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.	Milne RL et al.	—	2017	→
Identifying subtype-specific associations between gene expression and DNA methylation profiles in breast cancer.	Lee G et al.	—	2017	→
Impact of a Panel of 88 Single Nucleotide Polymorphisms on the Risk of Breast Cancer in High-Risk Women: Results From Two Randomized Tamoxifen Prevention Trials.	Cuzick J et al.	—	2017	→
Increased genomic burden of germline copy number variants is associated with early onset breast cancer: Australian breast cancer family registry.	Walker LC et al.	—	2017	→
Inherited Chromosomally Integrated Human Herpesvirus 6 and Breast Cancer.	Gravel A et al.	—	2017	→
Insights from Global Analyses of Long Noncoding RNAs in Breast Cancer.	Warburton AJ et al.	—	2017	→
Joint relative risks for estrogen receptor-positive breast cancer from a clinical model, polygenic risk score, and sex hormones.	Shieh Y et al.	—	2017	→
Kringle IV Type 2, Not Low Lipoprotein(a), as a Cause of Diabetes: A Novel Genetic Approach Using SNPs Associated Selectively with Lipoprotein(a) Concentrations or with Kringle IV Type 2 Repeats.	Tolbus A et al.	—	2017	→
Leveraging functional annotations in genetic risk prediction for human complex diseases.	Hu Y et al.	—	2017	→
Limited influence of germline genetic variation on all-cause mortality in women with early onset breast cancer: evidence from gene-based tests, single-marker regression, and whole-genome prediction.	Scannell Bryan M et al.	—	2017	→
Long Noncoding RNAs CUPID1 and CUPID2 Mediate Breast Cancer Risk at 11q13 by Modulating the Response to DNA Damage.	Betts JA et al.	—	2017	→
<i>BRCA2</i> Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer.	Shimelis H et al.	—	2017	→
Managing hereditary breast cancer risk in women with and without ovarian cancer.	Peters ML et al.	—	2017	→
Mechanisms of the anti-tumor activity of Methyl 2-(-5-fluoro-2-hydroxyphenyl)-1 H-benzo[d]imidazole-5-carboxylate against breast cancer in vitro and in vivo.	Hasanpourghadi M et al.	—	2017	→
miR-206 Inhibits Stemness and Metastasis of Breast Cancer by Targeting MKL1/IL11 Pathway.	Samaeekia R et al.	—	2017	→
Next-Generation Sequencing in Oncology: Genetic Diagnosis, Risk Prediction and Cancer Classification.	Kamps R et al.	—	2017	→
Next-generation sequencing of a family with a high penetrance of monoclonal gammopathies for the identification of candidate risk alleles.	Bolli N et al.	—	2017	→
OLA1 gene sequencing in patients with BRCA1/2 mutation-negative suspected hereditary breast and ovarian cancer.	Takahashi M et al.	—	2017	→
Pathway-based discovery of genetic interactions in breast cancer.	Wang W et al.	—	2017	→
Precancer Atlas to Drive Precision Prevention Trials.	Spira A et al.	—	2017	→
Predicting Triple-Negative Breast Cancer Subtype Using Multiple Single Nucleotide Polymorphisms for Breast Cancer Risk and Several Variable Selection Methods.	Häberle L et al.	—	2017	→
Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores.	Lecarpentier J et al.	—	2017	→
Previous GWAS hits in relation to young-onset breast cancer.	Shi M et al.	—	2017	→
Psychosocial and behavioral impact of breast cancer risk assessed by testing for common risk variants: protocol of a prospective study.	Yanes T et al.	—	2017	→
Rare, protein-truncating variants in <i>ATM</i>, <i>CHEK2</i> and <i>PALB2</i>, but not <i>XRCC2</i>, are associated with increased breast cancer risks.	Decker B et al.	—	2017	→
Risk and predictors of psoriasis in patients with breast cancer: a Swedish population-based cohort study.	Yang H et al.	—	2017	→
SNM1B/Apollo in the DNA damage response and telomere maintenance.	Schmiester M et al.	—	2017	→
The 30 kb deletion in the APOBEC3 cluster decreases APOBEC3A and APOBEC3B expression and creates a transcriptionally active hybrid gene but does not associate with breast cancer in the European population.	Klonowska K et al.	—	2017	→
The 30 kb deletion in the <i>APOBEC3</i> cluster decreases <i>APOBEC3A</i> and <i>APOBEC3B</i> expression and creates a transcriptionally active hybrid gene but does not associate with breast cancer in the European population.	Klonowska K et al.	—	2017	→
The ANDROMEDA prospective cohort study: predictive value of combined criteria to tailor breast cancer screening and new opportunities from circulating markers: study protocol.	Giordano L et al.	—	2017	→
The impact of a panel of 18 SNPs on breast cancer risk in women attending a UK familial screening clinic: a case-control study.	Evans DG et al.	—	2017	→
The impact of the Biomolecular Era on breast cancer surgery.	McVeigh TP et al.	—	2017	→
The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog).	MacArthur J et al.	—	2017	→
The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers.	Amos CI et al.	—	2017	→
TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer.	Fagerholm R et al.	—	2017	→
Trans-ethnic predicted expression genome-wide association analysis identifies a gene for estrogen receptor-negative breast cancer.	Gao G et al.	—	2017	→
Translating Germline Cancer Risk into Precision Prevention.	Yurgelun MB et al.	—	2017	→
Tumor characteristics and family history in relation to mammographic density and breast cancer: The French E3N cohort.	Maskarinec G et al.	—	2017	→
Using Breast Cancer Risk Associated Polymorphisms to Identify Women for Breast Cancer Chemoprevention.	Ziv E et al.	—	2017	→
A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast, and Colorectal Cancer.	Scarbrough PM et al.	—	2016	→
Admixture Mapping of African-American Women in the AMBER Consortium Identifies New Loci for Breast Cancer and Estrogen-Receptor Subtypes.	Ruiz-Narváez EA et al.	—	2016	→
A family-based, genome-wide association study of young-onset breast cancer: inherited variants and maternally mediated effects.	O'Brien KM et al.	—	2016	→
Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers.	Schmidt MK et al.	—	2016	→
A genome-wide association study identifies WT1 variant with better response to 5-fluorouracil, pirarubicin and cyclophosphamide neoadjuvant chemotherapy in breast cancer patients.	Wu L et al.	—	2016	→
A Genome-Wide Association Study to Identify Potential Germline Copy Number Variants for Sporadic Breast Cancer Susceptibility.	Sapkota Y et al.	—	2016	→
Alcohol and breast cancer tumor subtypes in a Spanish Cohort.	Gago-Dominguez M et al.	—	2016	→
Analysis of functional germline variants in APOBEC3 and driver genes on breast cancer risk in Moroccan study population.	Marouf C et al.	—	2016	→
An exome-wide analysis of low frequency and rare variants in relation to risk of breast cancer in African American Women: the AMBER Consortium.	Haddad SA et al.	—	2016	→
An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression.	Wyszynski A et al.	—	2016	→
An investigation of the association of genetic susceptibility risk with somatic mutation burden in breast cancer.	Zhu B et al.	—	2016	→
APOBEC3 deletion increases the risk of breast cancer: a meta-analysis.	Han Y et al.	—	2016	→
A Review of Whole-Exome Sequencing Efforts Toward Hereditary Breast Cancer Susceptibility Gene Discovery.	Chandler MR et al.	—	2016	→
Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21.	Hamdi Y et al.	—	2016	→
Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry.	Zhao Z et al.	—	2016	→
Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors.	Middlebrooks CD et al.	—	2016	→
Association of multiple genetic variants with breast cancer susceptibility in the Han Chinese population.	Li X et al.	—	2016	→
Association of transcription factor 7-like 2 gene polymorphisms with breast cancer risk in northwest Chinese women.	Min W et al.	—	2016	→
BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers.	Meeks HD et al.	—	2016	→
Breast Cancer: A Molecular and Redox Snapshot.	Raman D et al.	—	2016	→
Breast Cancer Risk From Modifiable and Nonmodifiable Risk Factors Among White Women in the United States.	Maas P et al.	—	2016	→
Breast cancer risk prediction using a clinical risk model and polygenic risk score.	Shieh Y et al.	—	2016	→
Breast Cancer Risk Prediction Using Clinical Models and 77 Independent Risk-Associated SNPs for Women Aged Under 50 Years: Australian Breast Cancer Family Registry.	Dite GS et al.	—	2016	→
[Breast cancer screening: On our way to the future].	Delaloge S et al.	—	2016	→
Calcium-Sensing Receptor Promotes Breast Cancer by Stimulating Intracrine Actions of Parathyroid Hormone-Related Protein.	Kim W et al.	—	2016	→
Cancer prevention as part of precision medicine: 'plenty to be done'.	Stewart BW et al.	—	2016	→
Cancer Prevention: Obstacles, Challenges and the Road Ahead.	Meyskens FL et al.	—	2016	→
Chemotherapy, Genetic Susceptibility, and Risk of Venous Thromboembolism in Breast Cancer Patients.	Brand JS et al.	—	2016	→
Cohort Profile: The Breast Cancer Prospective Family Study Cohort (ProF-SC).	Terry MB et al.	—	2016	→
Combined genetic and splicing analysis of BRCA1 c.[594-2A>C; 641A>G] highlights the relevance of naturally occurring in-frame transcripts for developing disease gene variant classification algorithms.	de la Hoya M et al.	—	2016	→
Common genetic susceptibility to DCIS and invasive ductal carcinoma.	Sopik V et al.	—	2016	→
Common germline variants within the CDKN2A/2B region affect risk of pancreatic neuroendocrine tumors.	Campa D et al.	—	2016	→
Common Variants Confer Susceptibility to Barrett's Esophagus: Insights from the First Genome-Wide Association Studies.	Palles C et al.	—	2016	→
Comparing Mammography Abnormality Features to Genetic Variants in the Prediction of Breast Cancer in Women Recommended for Breast Biopsy.	Burnside ES et al.	—	2016	→
Contralateral risk reducing mastectomy in Non-BRCA-Mutated patients.	Falco G et al.	—	2016	→
Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.	Fehringer G et al.	—	2016	→
Crucial considerations for pipelines to validate circulating biomarkers for breast cancer.	Ewaisha R et al.	—	2016	→
CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer.	Thompson DJ et al.	—	2016	→
Deep targeted sequencing of 12 breast cancer susceptibility regions in 4611 women across four different ethnicities.	Lindström S et al.	—	2016	→
Determining Which Phenotypes Underlie a Pleiotropic Signal.	Majumdar A et al.	—	2016	→
Discriminatory power of common genetic variants in personalized breast cancer diagnosis.	Wu Y et al.	—	2016	→
Downregulation of the Ca(2+)-activated K(+) channel KC a3.1 by histone deacetylase inhibition in human breast cancer cells.	Ohya S et al.	—	2016	→
Evaluation of ACMG-Guideline-Based Variant Classification of Cancer Susceptibility and Non-Cancer-Associated Genes in Families Affected by Breast Cancer.	Maxwell KN et al.	—	2016	→
Evaluation of a newly discovered breast cancer susceptibility locus at 6q25.1 in Iranian Azari-Turkish women.	Garehdaghchi Z et al.	—	2016	→
Evaluation of potential regulatory function of breast cancer risk locus at 6q25.1.	Sun Y et al.	—	2016	→
Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation.	Ghoussaini M et al.	—	2016	→
FGFR2 risk SNPs confer breast cancer risk by augmenting oestrogen responsiveness.	Campbell TM et al.	—	2016	→
Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus.	Horne HN et al.	—	2016	→
Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer.	Shi J et al.	—	2016	→
Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).	Darabi H et al.	—	2016	→
Five endometrial cancer risk loci identified through genome-wide association analysis.	Cheng TH et al.	—	2016	→
Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.	Lawrenson K et al.	—	2016	→
Functional single nucleotide polymorphisms within the cyclin-dependent kinase inhibitor 2A/2B region affect pancreatic cancer risk.	Campa D et al.	—	2016	→
Gene-environment interaction and risk of breast cancer.	Rudolph A et al.	—	2016	→
GENESIS: a French national resource to study the missing heritability of breast cancer.	Sinilnikova OM et al.	—	2016	→
Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.	Guo Y et al.	—	2016	→
Genetic and Epigenetic Regulation of TOX3 Expression in Breast Cancer.	Han YJ et al.	—	2016	→
Genetic predisposition to ductal carcinoma in situ of the breast.	Petridis C et al.	—	2016	→
Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer.	Painter JN et al.	—	2016	→
Genetic variants in microRNA and microRNA biogenesis pathway genes and breast cancer risk among women of African ancestry.	Qian F et al.	—	2016	→
Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium.	Lei J et al.	—	2016	→
Genetic variation in the insulin, insulin-like growth factor, growth hormone, and leptin pathways in relation to breast cancer in African-American women: the AMBER consortium.	Ruiz-Narváez EA et al.	—	2016	→
Genome-wide association studies in women of African ancestry identified 3q26.21 as a novel susceptibility locus for oestrogen receptor negative breast cancer.	Huo D et al.	—	2016	→
Genome-wide association study in East Asians identifies two novel breast cancer susceptibility loci.	Han MR et al.	—	2016	→
Genomic Biomarkers for Breast Cancer Risk.	Walsh MF et al.	—	2016	→
Genomic Disparities in Breast Cancer Among Latinas.	Lynce F et al.	—	2016	→
How Can We Explain Very Low Odds Ratios in GWAS? I. Polygenic Models.	Hodge SE et al.	—	2016	→
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer.	Couch FJ et al.	—	2016	→
Identification of Gene Mutations and Fusion Genes in Patients with Sézary Syndrome.	Prasad A et al.	—	2016	→
Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus.	Zeng C et al.	—	2016	→
Identification of novel susceptibility markers for the risk of overall breast cancer as well as subtypes defined by hormone receptor status in the Chinese population.	Deng Z et al.	—	2016	→
Incorporating Functional Genomic Information in Genetic Association Studies Using an Empirical Bayes Approach.	Spencer AV et al.	—	2016	→
Incorporating truncating variants in PALB2, CHEK2, and ATM into the BOADICEA breast cancer risk model.	Lee AJ et al.	—	2016	→
Integrative analyses reveal signaling pathways underlying familial breast cancer susceptibility.	Piccolo SR et al.	—	2016	→
Managing breast cancer in younger women: challenges and solutions.	Ademuyiwa FO et al.	—	2016	→
Mapping hyper-susceptibility to colitis-associated colorectal cancer in FVB/NJ mice.	Van Der Kraak L et al.	—	2016	→
Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women.	Wang Z et al.	—	2016	→
Modifiers of breast and ovarian cancer risks for BRCA1 and BRCA2 mutation carriers.	Milne RL et al.	—	2016	→
Multigene testing of moderate-risk genes: be mindful of the missense.	Young EL et al.	—	2016	→
No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.	Ovarian Cancer Association Consortium et al.	—	2016	→
No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing.	Easton DF et al.	—	2016	→
PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS.	Southey MC et al.	—	2016	→
PALB2: research reaching to clinical outcomes for women with breast cancer.	Southey MC et al.	—	2016	→
Patient survival and tumor characteristics associated with CHEK2:p.I157T - findings from the Breast Cancer Association Consortium.	Muranen TA et al.	—	2016	→
Patients with a High Polygenic Risk of Breast Cancer do not have An Increased Risk of Radiotherapy Toxicity.	Dorling L et al.	—	2016	→
Polygenic Epidemiology.	Dudbridge F	—	2016	→
Polygenic risk score is associated with increased disease risk in 52 Finnish breast cancer families.	Muranen TA et al.	—	2016	→
Polymorphisms in cancer susceptibility genes XRCC1, RAD51 and TP53 and the risk of breast cancer in Serbian women.	Krivokuca AM et al.	—	2016	→
Polymorphisms in the estrogen receptor alpha gene (ESR1), daily cycling estrogen and mammographic density phenotypes.	Fjeldheim FN et al.	—	2016	→
Prediction of breast cancer risk based on common genetic variants in women of East Asian ancestry.	Wen W et al.	—	2016	→
Quantifying the utility of single nucleotide polymorphisms to guide colorectal cancer screening.	Jenkins MA et al.	—	2016	→
RAD51B in Familial Breast Cancer.	Pelttari LM et al.	—	2016	→
Rare SNPs in receptor tyrosine kinases are negative outcome predictors in multiple myeloma.	Keppler S et al.	—	2016	→
Reclassification of genetic-based risk predictions as GWAS data accumulate.	Krier J et al.	—	2016	→
Recommendations on breast cancer screening and prevention in the context of implementing risk stratification: impending changes to current policies.	Gagnon J et al.	—	2016	→
Regulators of genetic risk of breast cancer identified by integrative network analysis.	Castro MA et al.	—	2016	→
Replication of <i>Early B-cell Factor 1 (EBF1)</i> Gene-by-psychosocial Stress Interaction Effects on Central Adiposity in a Korean Population.	Kim HJ et al.	—	2016	→
rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk.	Liu J et al.	—	2016	→
Screening of HELQ in breast and ovarian cancer families.	Pelttari LM et al.	—	2016	→
Search for new loci and low-frequency variants influencing glioma risk by exome-array analysis.	Kinnersley B et al.	—	2016	→
Single nucleotide polymorphisms in clinics: Fantasy or reality for cancer?	Srinivasan S et al.	—	2016	→
Structure-Leveraged Methods in Breast Cancer Risk Prediction.	Fan J et al.	—	2016	→
Telomere structure and maintenance gene variants and risk of five cancer types.	Karami S et al.	—	2016	→
The Contribution of Cholesterol and Its Metabolites to the Pathophysiology of Breast Cancer.	Baek AE et al.	—	2016	→
The genetics of breast cancer risk in the post-genome era: thoughts on study design to move past BRCA and towards clinical relevance.	Skol AD et al.	—	2016	→
The Genome Conformation As an Integrator of Multi-Omic Data: The Example of Damage Spreading in Cancer.	Tordini F et al.	—	2016	→
The Heritability of Breast Cancer among Women in the Nordic Twin Study of Cancer.	Möller S et al.	—	2016	→
The latent class twin method.	Baker SG	—	2016	→
The precision relationships between eight GWAS-identified genetic variants and breast cancer in a Chinese population.	Chen Y et al.	—	2016	→
The Relationship between Common Genetic Markers of Breast Cancer Risk and Chemotherapy-Induced Toxicity: A Case-Control Study.	Dorling L et al.	—	2016	→
The role of germline alterations in the DNA damage response genes BRIP1 and BRCA2 in melanoma susceptibility.	Tuominen R et al.	—	2016	→
The SDF-1 rs1801157 Polymorphism is Associated with Cancer Risk: An Update Pooled Analysis and FPRP Test of 17,876 Participants.	Tong X et al.	—	2016	→
Tissue-specific Co-expression of Long Non-coding and Coding RNAs Associated with Breast Cancer.	Wu W et al.	—	2016	→
Trans-ethnic follow-up of breast cancer GWAS hits using the preferential linkage disequilibrium approach.	Zhu Q et al.	—	2016	→
Women at high risk of breast cancer: Molecular characteristics, clinical presentation and management.	Kleibl Z et al.	—	2016	→
A comprehensive evaluation of interaction between genetic variants and use of menopausal hormone therapy on mammographic density.	Rudolph A et al.	—	2015	→
A concordance index for matched case-control studies with applications in cancer risk.	Brentnall AR et al.	—	2015	→
Adjusting the frequency of mammography screening on the basis of genetic risk: Attitudes among women in the UK.	Meisel SF et al.	—	2015	→
A mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li-Fraumeni-like families.	Calvete O et al.	—	2015	→
Analysis of large mutations in BARD1 in patients with breast and/or ovarian cancer: the Polish population as an example.	Klonowska K et al.	—	2015	→
An epidemiological perspective of personalized medicine: the Estonian experience.	Milani L et al.	—	2015	→
A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2.	Vachon CM et al.	—	2015	→
A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients.	Seibold P et al.	—	2015	→
A rare truncating BRCA2 variant and genetic susceptibility to upper aerodigestive tract cancer.	Delahaye-Sourdeix M et al.	—	2015	→
A risk prediction algorithm for ovarian cancer incorporating BRCA1, BRCA2, common alleles and other familial effects.	Jervis S et al.	—	2015	→
Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers.	Blanco I et al.	—	2015	→
Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy.	Lei J et al.	—	2015	→
Association between polymorphisms in cdc27 and breast cancer in a Chinese population.	Guo H et al.	—	2015	→
Association between WT1 polymorphisms and susceptibility to breast cancer: results from a case-control study in a southwestern Chinese population.	Qi XW et al.	—	2015	→
Associations among ancestry, geography and breast cancer incidence, mortality, and survival in Trinidad and Tobago.	Warner WA et al.	—	2015	→
Associations between breast density and a panel of single nucleotide polymorphisms linked to breast cancer risk: a cohort study with digital mammography.	Keller BM et al.	—	2015	→
BMX Negatively Regulates BAK Function, Thereby Increasing Apoptotic Resistance to Chemotherapeutic Drugs.	Fox JL et al.	—	2015	→
BRCA2-branching out too?	Spitz MR et al.	—	2015	→
Breast cancer genetic risk profile is differentially associated with interval and screen-detected breast cancers.	Li J et al.	—	2015	→
Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk.	Carvajal-Carmona LG et al.	—	2015	→
Clinical implications of genomics for cancer risk genetics.	Thomas DM et al.	—	2015	→
Common germline polymorphisms associated with breast cancer-specific survival.	Pirie A et al.	—	2015	→
Common polygenic variation enhances risk prediction for Alzheimer's disease.	Escott-Price V et al.	—	2015	→
Common variants at 10p12.31, 10q21.1 and 13q12.13 are associated with sporadic pituitary adenoma.	Ye Z et al.	—	2015	→
Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer.	Lawrenson K et al.	—	2015	→
Common variants identified in genome-wide association studies of testicular germ cell tumour: an update, biological insights and clinical application.	Litchfield K et al.	—	2015	→
Comorbidity of physical and mental disorders in the neurodevelopmental genomics cohort study.	Merikangas KR et al.	—	2015	→
Concurrent DNA Copy-Number Alterations and Mutations in Genes Related to Maintenance of Genome Stability in Uninvolved Mammary Glandular Tissue from Breast Cancer Patients.	Ronowicz A et al.	—	2015	→
Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer.	Hung RJ et al.	—	2015	→
Dendrimer complexed hydrogel for local delivery of PTX to inhibit recurrence of breast cancer.	Hu J et al.	—	2015	→
Detection of novel germline mutations for breast cancer in non-BRCA1/2 families.	Aloraifi F et al.	—	2015	→
Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci.	Trynka G et al.	—	2015	→
Do Health Professionals Need Additional Competencies for Stratified Cancer Prevention Based on Genetic Risk Profiling?	Chowdhury S et al.	—	2015	→
Endometriosis as a risk factor for ovarian or endometrial cancer - results of a hospital-based case-control study.	Burghaus S et al.	—	2015	→
Epigenome-wide association studies (EWAS): past, present, and future.	Flanagan JM	—	2015	→
Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study.	Lee AW et al.	—	2015	→
Expression quantitative trait locus analysis for translational medicine.	Gibson G et al.	—	2015	→
FGFR2 gene polymorphisms are associated with breast cancer risk in the Han Chinese population.	Xia P et al.	—	2015	→
Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.	Orr N et al.	—	2015	→
Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.	Painter JN et al.	—	2015	→
Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk.	Guo X et al.	—	2015	→
Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1.	Glubb DM et al.	—	2015	→
From candidate gene studies to GWAS and post-GWAS analyses in breast cancer.	Fachal L et al.	—	2015	→
Functional classification of BRCA2 DNA variants by splicing assays in a large minigene with 9 exons.	Acedo A et al.	—	2015	→
Functional polymorphisms in cancer.	Agarwal D et al.	—	2015	→
Gene-expression patterns in peripheral blood classify familial breast cancer susceptibility.	Piccolo SR et al.	—	2015	→
Gene-panel sequencing and the prediction of breast-cancer risk.	Easton DF et al.	—	2015	→
Genetics of endometriosis.	Rahmioglu N et al.	—	2015	→
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.	Michailidou K et al.	—	2015	→
Genome-wide association study of susceptibility loci for breast cancer in Sardinian population.	Palomba G et al.	—	2015	→
Genome-wide significant risk associations for mucinous ovarian carcinoma.	Kelemen LE et al.	—	2015	→
Genotyping of Single Nucleotide Polymorphisms in DNA Isolated from Serum Using Sequenom MassARRAY Technology.	Clendenen TV et al.	—	2015	→
Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian Randomization.	Zhang B et al.	—	2015	→
Homogeneous case subgroups increase power in genetic association studies.	Traylor M et al.	—	2015	→
Hormone-related pathways and risk of breast cancer subtypes in African American women.	Haddad SA et al.	—	2015	→
How cancer cells hijack DNA double-strand break repair pathways to gain genomic instability.	Jeggo PA et al.	—	2015	→
Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk.	Lin WY et al.	—	2015	→
Identification of four new susceptibility loci for testicular germ cell tumour.	Litchfield K et al.	—	2015	→
Identification of novel genetic markers of breast cancer survival.	Guo Q et al.	—	2015	→
Identification of two novel mammographic density loci at 6Q25.1.	Brand JS et al.	—	2015	→
Implementation of genome-wide complex trait analysis to quantify the heritability in multiple myeloma.	Mitchell JS et al.	—	2015	→
Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer.	Kabisch M et al.	—	2015	→
In Search for the Genetic Basis of Quality of Life in Healthy Swedish Women--A GWAS Study Using the iCOGS Custom Genotyping Array.	Schoormans D et al.	—	2015	→
Insight in genome-wide association of metabolite quantitative traits by exome sequence analyses.	Demirkan A et al.	—	2015	→
Interaction between common breast cancer susceptibility variants, genetic ancestry, and nongenetic risk factors in Hispanic women.	Fejerman L et al.	—	2015	→
Investigation of gene-environment interactions between 47 newly identified breast cancer susceptibility loci and environmental risk factors.	Rudolph A et al.	—	2015	→
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.	Day FR et al.	—	2015	→
Leveraging Interaction between Genetic Variants and Mammographic Findings for Personalized Breast Cancer Diagnosis.	Liu J et al.	—	2015	→
Making sense of GWAS: using epigenomics and genome engineering to understand the functional relevance of SNPs in non-coding regions of the human genome.	Tak YG et al.	—	2015	→
Mammographic Breast Density and Common Genetic Variants in Breast Cancer Risk Prediction.	Lee CP et al.	—	2015	→
Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.	Cheng TH et al.	—	2015	→
Methods of integrating data to uncover genotype-phenotype interactions.	Ritchie MD et al.	—	2015	→
Microarray expression profile analysis of long non-coding RNAs in human breast cancer: a study of Chinese women.	Xu N et al.	—	2015	→
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.	Vilhjálmsson BJ et al.	—	2015	→
Molecular drivers of lobular carcinoma in situ.	Logan GJ et al.	—	2015	→
Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors.	Caswell JL et al.	—	2015	→
Multi-stage genome-wide association study identifies new susceptibility locus for testicular germ cell tumour on chromosome 3q25.	Litchfield K et al.	—	2015	→
Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk.	Kar SP et al.	—	2015	→
Novel Associations between Common Breast Cancer Susceptibility Variants and Risk-Predicting Mammographic Density Measures.	Stone J et al.	—	2015	→
Novel bayes factors that capture expert uncertainty in prior density specification in genetic association studies.	Spencer AV et al.	—	2015	→
Personalized Medicine Through SNP Testing for Breast Cancer Risk: Clinical Implementation.	Howe R et al.	—	2015	→
Personalized Screening for Breast Cancer: A Wolf in Sheep's Clothing?	Feig SA	—	2015	→
Polygenic risk of Parkinson disease is correlated with disease age at onset.	Escott-Price V et al.	—	2015	→
Polygenic susceptibility to testicular cancer: implications for personalised health care.	Litchfield K et al.	—	2015	→
Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression.	Darabi H et al.	—	2015	→
Potentially functional polymorphisms in aminoacyl-tRNA synthetases genes are associated with breast cancer risk in a Chinese population.	He Y et al.	—	2015	→
Powerful Tukey's One Degree-of-Freedom Test for Detecting Gene-Gene and Gene-Environment Interactions.	Wang Y et al.	—	2015	→
Prediction of breast cancer risk based on profiling with common genetic variants.	Mavaddat N et al.	—	2015	→
Putative linkage signals identified for breast cancer in African American families.	Ochs-Balcom HM et al.	—	2015	→
Quantifying the heritability of testicular germ cell tumour using both population-based and genomic approaches.	Litchfield K et al.	—	2015	→
RAD51, XRCC3, and XRCC2 mutation screening in Finnish breast cancer families.	Pelttari LM et al.	—	2015	→
Reevaluation of the BRCA2 truncating allele c.9976A > T (p.Lys3326Ter) in a familial breast cancer context.	Thompson ER et al.	—	2015	→
SNPs and breast cancer risk prediction for African American and Hispanic women.	Allman R et al.	—	2015	→
SNP-SNP interaction analysis of NF-κB signaling pathway on breast cancer survival.	Jamshidi M et al.	—	2015	→
Targeted Cancer Screening in Average-Risk Individuals.	Marcus PM et al.	—	2015	→
The association of copy number variation and percent mammographic density.	Atkinson EJ et al.	—	2015	→
The Associations between RNA Splicing Complex Gene SF3A1 Polymorphisms and Colorectal Cancer Risk in a Chinese Population.	Chen X et al.	—	2015	→
The contributions of breast density and common genetic variation to breast cancer risk.	Vachon CM et al.	—	2015	→
The development and characterization of a 57K single nucleotide polymorphism array for rainbow trout.	Palti Y et al.	—	2015	→
The evolution of cancer surgery and future perspectives.	Wyld L et al.	—	2015	→
The genetic basis of quality of life in healthy Swedish women: a candidate gene approach.	Schoormans D et al.	—	2015	→
The influence of cancer tissue sampling on the identification of cancer characteristics.	Xu H et al.	—	2015	→
The landscape of long noncoding RNAs in the human transcriptome.	Iyer MK et al.	—	2015	→
The Prediction of Radiotherapy Toxicity Using Single Nucleotide Polymorphism-Based Models: A Step Toward Prevention.	Kerns SL et al.	—	2015	→
The Role of Constitutional Copy Number Variants in Breast Cancer.	Walker LC et al.	—	2015	→
The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients.	Fagerholm R et al.	—	2015	→
The use of the Gail model, body mass index and SNPs to predict breast cancer among women with abnormal (BI-RADS 4) mammograms.	McCarthy AM et al.	—	2015	→
Tumour spectrum in non-BRCA hereditary breast cancer families in Sweden.	Wendt C et al.	—	2015	→
Using Network Methodology to Infer Population Substructure.	Prokopenko D et al.	—	2015	→
2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy.	Li J et al.	—	2014	→
A collaborative study of the etiology of breast cancer subtypes in African American women: the AMBER consortium.	Palmer JR et al.	—	2014	→
A comprehensive examination of breast cancer risk loci in African American women.	Feng Y et al.	—	2014	→
Additive interactions between susceptibility single-nucleotide polymorphisms identified in genome-wide association studies and breast cancer risk factors in the Breast and Prostate Cancer Cohort Consortium.	Joshi AD et al.	—	2014	→
A functional p53 responsive polymorphism in KITLG, rs4590952, does not affect the risk of breast cancer.	Chen W et al.	—	2014	→
A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity.	Barnett GC et al.	—	2014	→
A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.	Ahsan H et al.	—	2014	→
A genome-wide "pleiotropy scan" does not identify new susceptibility loci for estrogen receptor negative breast cancer.	Campa D et al.	—	2014	→
A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium.	Milne RL et al.	—	2014	→
A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.	Al Olama AA et al.	—	2014	→
Analyzing 395,793 samples shows significant association between rs999737 polymorphism and breast cancer.	Dong H et al.	—	2014	→
A novel estrogen receptor-microRNA 190a-PAR-1-pathway regulates breast cancer progression, a finding initially suggested by genome-wide analysis of loci associated with lymph-node metastasis.	Chu HW et al.	—	2014	→
Architecture of inherited susceptibility to colorectal cancer: a voyage of discovery.	Whiffin N et al.	—	2014	→
Area and volumetric density estimation in processed full-field digital mammograms for risk assessment of breast cancer.	Cheddad A et al.	—	2014	→
A resource of single-nucleotide polymorphisms for rainbow trout generated by restriction-site associated DNA sequencing of doubled haploids.	Palti Y et al.	—	2014	→
Association of genetic variants at TOX3, 2q35 and 8q24 with the risk of familial and early-onset breast cancer in a South-American population.	Elematore I et al.	—	2014	→
Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers.	Kuchenbaecker KB et al.	—	2014	→
Association study of susceptibility loci with specific breast cancer subtypes in Chinese women.	Zhang B et al.	—	2014	→
Association study of TGFBR2 and miR-518 gene polymorphisms with age at natural menopause, premature ovarian failure, and early menopause among Chinese Han women.	Ma X et al.	—	2014	→
Asymmetry in family history implicates nonstandard genetic mechanisms: application to the genetics of breast cancer.	Weinberg CR et al.	—	2014	→
Automated measurement of volumetric mammographic density: a tool for widespread breast cancer risk assessment.	Brand JS et al.	—	2014	→
Biomarkers in women's cancers, gynecology, and obstetrics.	Fasching PA et al.	—	2014	→
BOADICEA breast cancer risk prediction model: updates to cancer incidences, tumour pathology and web interface.	Lee AJ et al.	—	2014	→
Breast and prostate cancer: an analysis of common epidemiological features in mortality trends in Spain.	López-Abente G et al.	—	2014	→
Breast cancer in Sub-Saharan Africa: opportunities for prevention.	Brinton LA et al.	—	2014	→
Breast cancer risk assessment using genetic variants and risk factors in a Singapore Chinese population.	Lee CP et al.	—	2014	→
Breast cancer subtypes and previously established genetic risk factors: a bayesian approach.	O'Brien KM et al.	—	2014	→
Breast cancer susceptibility loci in association with age at menarche, age at natural menopause and the reproductive lifespan.	Warren Andersen S et al.	—	2014	→
Breast cancer susceptibility risk associations and heterogeneity by E-cadherin tumor tissue expression.	Horne HN et al.	—	2014	→
Breast cancer susceptibility variants and mammographic density phenotypes in norwegian postmenopausal women.	Ellingjord-Dale M et al.	—	2014	→
Breast density and breast cancer risk: a practical review.	Wang AT et al.	—	2014	→
Cancer genomics and inherited risk.	Stadler ZK et al.	—	2014	→
Candidate gene-environment interactions in breast cancer.	Fletcher O et al.	—	2014	→
Combined associations of genetic and environmental risk factors: implications for prevention of breast cancer.	Garcia-Closas M et al.	—	2014	→
Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium.	Milne RL et al.	—	2014	→
Cross-cancer pleiotropic analysis of endometrial cancer: PAGE and E2C2 consortia.	Setiawan VW et al.	—	2014	→
CXM: a new tool for mapping breast cancer risk in the tumor microenvironment.	Flister MJ et al.	—	2014	→
Differences in DNA methylation by extent of breast cancer family history in unaffected women.	Delgado-Cruzata L et al.	—	2014	→
Distribution of breast cancer risk from SNPs and classical risk factors in women of routine screening age in the UK.	Brentnall AR et al.	—	2014	→
DNA methylation levels at chromosome 8q24 in peripheral blood are associated with 8q24 cancer susceptibility loci.	Barry KH et al.	—	2014	→
Enhancement of mammographic density measures in breast cancer risk prediction.	Cheddad A et al.	—	2014	→
Epigenome-wide methylation in DNA from peripheral blood as a marker of risk for breast cancer.	Severi G et al.	—	2014	→
Eurocan Platform meeting: European recommendations for biomarker-based chemoprevention trials.	Cairns L	—	2014	→
Evaluation of the RHINO gene for breast cancer predisposition in Finnish breast cancer families.	Heikkinen T et al.	—	2014	→
Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.	Ghoussaini M et al.	—	2014	→
Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancer.	Kiiski JI et al.	—	2014	→
Expanding the genetic basis of copy number variation in familial breast cancer.	Masson AL et al.	—	2014	→
Expression of the microtubule-associated protein MAP9/ASAP and its partners AURKA and PLK1 in colorectal and breast cancers.	Rouquier S et al.	—	2014	→
Expression QTL-based analyses reveal candidate causal genes and loci across five tumor types.	Li Q et al.	—	2014	→
Familial transmission of prostate, breast and colorectal cancer in adoptees is related to cancer in biological but not in adoptive parents: a nationwide family study.	Zöller B et al.	—	2014	→
FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium.	Agarwal D et al.	—	2014	→
Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease.	Leongamornlert D et al.	—	2014	→
Functional variants at the 21q22.3 locus involved in breast cancer progression identified by screening of genome-wide estrogen response elements.	Hsiung CN et al.	—	2014	→
[Future of mammography-based imaging].	Schulz-Wendtland R et al.	—	2014	→
Gene-Lifestyle Interactions in Complex Diseases: Design and Description of the GLACIER and VIKING Studies.	Kurbasic A et al.	—	2014	→
Genetic predisposition to in situ and invasive lobular carcinoma of the breast.	Sawyer E et al.	—	2014	→
Genetic risk transmission in a family affected by familial breast cancer.	Pilato B et al.	—	2014	→
Genetics of gene expression in immunity to infection.	Fairfax BP et al.	—	2014	→
Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study.	Johnson N et al.	—	2014	→
Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade.	Purrington KS et al.	—	2014	→
Genome network medicine: innovation to overcome huge challenges in cancer therapy.	Roukos DH	—	2014	→
Genome-wide association analyses identify variants in developmental genes associated with hypospadias.	Geller F et al.	—	2014	→
Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1.	Cai Q et al.	—	2014	→
Genome-wide association studies and the clinic: a focus on breast cancer.	Véron A et al.	—	2014	→
Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer.	Purrington KS et al.	—	2014	→
Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk.	Lindström S et al.	—	2014	→
Genome-wide association study of breast cancer in Latinas identifies novel protective variants on 6q25.	Fejerman L et al.	—	2014	→
Germline DNA variations in breast cancer predisposition and prognosis: a systematic review of the literature.	Sapkota Y	—	2014	→
Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing.	Bodian DL et al.	—	2014	→
How many etiological subtypes of breast cancer: two, three, four, or more?	Anderson WF et al.	—	2014	→
Identification of new genetic susceptibility loci for breast cancer through consideration of gene-environment interactions.	Schoeps A et al.	—	2014	→
Impact of caspase-8 (CASP8) -652 6N del and D302H polymorphisms on prostate cancer in different ethnic groups.	Zhang CD et al.	—	2014	→
Implementing risk-stratified screening for common cancers: a review of potential ethical, legal and social issues.	Hall AE et al.	—	2014	→
inPHAP: interactive visualization of genotype and phased haplotype data.	Jäger G et al.	—	2014	→
Integrating gene expression and epidemiological data for the discovery of genetic interactions associated with cancer risk.	Bonifaci N et al.	—	2014	→
Integrating germline and somatic data towards a personalized cancer medicine.	Pujana MA	—	2014	→
Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.	Zhang B et al.	—	2014	→
Laying a solid foundation for Manhattan--'setting the functional basis for the post-GWAS era'.	Zhang X et al.	—	2014	→
Leveraging family history in population-based case-control association studies.	Ghosh A et al.	—	2014	→
MicroRNA related polymorphisms and breast cancer risk.	Khan S et al.	—	2014	→
Microsatellite genotyping reveals a signature in breast cancer exomes.	McIver LJ et al.	—	2014	→
Mutation analysis of the ERCC4/FANCQ gene in hereditary breast cancer.	Kohlhase S et al.	—	2014	→
Naturally occurring cancers in dogs: insights for translational genetics and medicine.	Alvarez CE	—	2014	→
New genetic variants improve personalized breast cancer diagnosis.	Liu J et al.	—	2014	→
NUSAP1 influences the DNA damage response by controlling BRCA1 protein levels.	Kotian S et al.	—	2014	→
On the identification of potential regulatory variants within genome wide association candidate SNP sets.	Chen CY et al.	—	2014	→
Opportunities and challenges of next-generation DNA sequencing for breast units.	Pilgrim SM et al.	—	2014	→
PALB2 sequencing in Italian familial breast cancer cases reveals a high-risk mutation recurrent in the province of Bergamo.	Catucci I et al.	—	2014	→
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.	Perry JR et al.	—	2014	→
Polymorphisms in circadian genes, night work and breast cancer: results from the GENICA study.	Rabstein S et al.	—	2014	→
Polymorphisms in the RANK/RANKL genes and their effect on bone specific prognosis in breast cancer patients.	Hein A et al.	—	2014	→
Post-GWAS gene-environment interplay in breast cancer: results from the Breast and Prostate Cancer Cohort Consortium and a meta-analysis on 79,000 women.	Barrdahl M et al.	—	2014	→
Prevalence of PALB2 mutation c.509_510delGA in unselected breast cancer patients from Central and Eastern Europe.	Noskowicz M et al.	—	2014	→
Prognostic information of a previously diagnosed sister is an independent prognosticator for a newly diagnosed sister with breast cancer.	Lindström LS et al.	—	2014	→
Rare coding variants and breast cancer risk: evaluation of susceptibility Loci identified in genome-wide association studies.	Zhang Y et al.	—	2014	→
Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study.	Damiola F et al.	—	2014	→
Rare mutations in RINT1 predispose carriers to breast and Lynch syndrome-spectrum cancers.	Park DJ et al.	—	2014	→
Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.	Wang Y et al.	—	2014	→
Risk determination and prevention of breast cancer.	Howell A et al.	—	2014	→
Should we keep on? Looking into pharmacogenomics of ADHD in adulthood from a different perspective.	Rovaris DL et al.	—	2014	→
Significant overlap between human genome-wide association-study nominated breast cancer risk alleles and rat mammary cancer susceptibility loci.	Sanders J et al.	—	2014	→
Targeting fibroblast growth factor receptor in breast cancer: a promise or a pitfall?	Bedussi F et al.	—	2014	→
The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors.	Quigley DA et al.	—	2014	→
The effect of tamoxifen on expression of ER, PR, Cerb-B2, and ki-67 in C3H mice spontaneous breast cancer model and the relation with chemotherapeutic effect.	Li X et al.	—	2014	→
The NLR-related protein NWD1 is associated with prostate cancer and modulates androgen receptor signaling.	Correa RG et al.	—	2014	→
The role of genome sequencing in personalized breast cancer prevention.	Sieh W et al.	—	2014	→
Two decades after BRCA: setting paradigms in personalized cancer care and prevention.	Couch FJ et al.	—	2014	→
Type II transmembrane serine protease gene variants associate with breast cancer.	Luostari K et al.	—	2014	→
Validation of six genetic determinants of susceptibility to estrogen-induced mammary cancer in the rat and assessment of their relevance to breast cancer risk in humans.	Colletti JA et al.	—	2014	→
Variants of estrogen-related genes and breast cancer risk in European and African American women.	Quan L et al.	—	2014	→
Volumetric mammographic density: heritability and association with breast cancer susceptibility loci.	Brand JS et al.	—	2014	→
A common deletion in the APOBEC3 genes and breast cancer risk.	Long J et al.	—	2013	→
A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk.	Pooley KA et al.	—	2013	→
APOBEC3 deletion polymorphism is associated with breast cancer risk among women of European ancestry.	Xuan D et al.	—	2013	→
Association between TCF7L2 gene polymorphism and cancer risk: a meta-analysis.	Chen J et al.	—	2013	→
Assumptions and properties of limiting pathway models for analysis of epistasis in complex traits.	Stringer S et al.	—	2013	→
Beyond BRCA1/2: polygenic, 'polyfunctional' molecular circuitry model to predict breast cancer risk.	Lianos GD et al.	—	2013	→
Beyond GWASs: illuminating the dark road from association to function.	Edwards SL et al.	—	2013	→
Breast Cancer Risk - From Genetics to Molecular Understanding of Pathogenesis.	Fasching PA et al.	—	2013	→
Breast cancer screening: time to target women at risk.	Hall P et al.	—	2013	→
Common breast cancer risk variants in the post-COGS era: a comprehensive review.	Maxwell KN et al.	—	2013	→
Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls.	Zheng W et al.	—	2013	→
Comprehensive functional annotation of seventy-one breast cancer risk Loci.	Rhie SK et al.	—	2013	→
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.	Eccles SA et al.	—	2013	→
Estimating single nucleotide polymorphism associations using pedigree data: applications to breast cancer.	Barnes DR et al.	—	2013	→
Evaluating genome-wide association study-identified breast cancer risk variants in African-American women.	Long J et al.	—	2013	→
Evolving paradigm for imaging, diagnosis, and management of DCIS.	Wells CJ et al.	—	2013	→
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.	Meyer KB et al.	—	2013	→
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers.	French JD et al.	—	2013	→
Gene-environment interactions in cancer epidemiology: a National Cancer Institute Think Tank report.	Hutter CM et al.	—	2013	→
Genetic modifiers of menopausal hormone replacement therapy and breast cancer risk: a genome-wide interaction study.	Rudolph A et al.	—	2013	→
Genetic susceptibility to triple-negative breast cancer.	Stevens KN et al.	—	2013	→
Genome-wide association studies identify four ER negative-specific breast cancer risk loci.	Garcia-Closas M et al.	—	2013	→
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.	Couch FJ et al.	—	2013	→
Genome-wide association study of breast cancer in the Japanese population.	Low SK et al.	—	2013	→
Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.	Haiman CA et al.	—	2013	→
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.	Pharoah PD et al.	—	2013	→
Harnessing the genome for characterization of G-protein coupled receptors in cancer pathogenesis.	Feigin ME	—	2013	→
Hereditary breast cancer: ever more pieces to the polygenic puzzle.	Bogdanova N et al.	—	2013	→
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.	Eeles RA et al.	—	2013	→
Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk.	Gaudet MM et al.	—	2013	→
Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14.	Ruark E et al.	—	2013	→
Inherited genetic susceptibility to breast cancer: the beginning of the end or the end of the beginning?	Ghoussaini M et al.	—	2013	→
Into the eye of the storm: breast cancer's somatic mutation landscape points to DNA damage and repair.	Ngeow J et al.	—	2013	→
Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size.	Li J et al.	—	2013	→
Lessons from postgenome-wide association studies: functional analysis of cancer predisposition loci.	Monteiro AN et al.	—	2013	→
Lessons learned and challenges posed in cancer genetics. Introduction.	Simard J et al.	—	2013	→
Manipulating the Mouse Genome Using Recombineering.	Biswas K et al.	—	2013	→
Mapping inherited and somatic variation in regulatory DNA: new roadmap for common disease clinical discoveries.	Roukos DH et al.	—	2013	→
Master regulators of FGFR2 signalling and breast cancer risk.	Fletcher MN et al.	—	2013	→
Meta-analysis methods for genome-wide association studies and beyond.	Evangelou E et al.	—	2013	→
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.	Bojesen SE et al.	—	2013	→
New breast cancer risk variant discovered at 10q25 in East Asian women.	Shi J et al.	—	2013	→
Parathyroid hormone-related protein specifies the mammary mesenchyme and regulates embryonic mammary development.	Hiremath M et al.	—	2013	→
Personalized screening for cancers: should we consider polygenic profiling?	Pashayan N et al.	—	2013	→
Potentially functional polymorphisms in ATG10 are associated with risk of breast cancer in a Chinese population.	Qin Z et al.	—	2013	→
Public attitudes towards genomic risk profiling as a component of routine population screening.	Nicholls SG et al.	—	2013	→
Public health genomics and personalized prevention: lessons from the COGS project.	Pashayan N et al.	—	2013	→
Quantitative assessment of common genetic variants on chromosome 5p12 and hormone receptor status with breast cancer risk.	Yu Y et al.	—	2013	→
Screening: biology dictates the fate of young women with breast cancer.	Eklund M et al.	—	2013	→
Telomeres and human health.	Bojesen SE	—	2013	→
The associations between a polygenic score, reproductive and menstrual risk factors and breast cancer risk.	Warren Andersen S et al.	—	2013	→
The complex genetic landscape of familial breast cancer.	Melchor L et al.	—	2013	→
The impact of next generation sequencing on the analysis of breast cancer susceptibility: a role for extremely rare genetic variation?	Hilbers FS et al.	—	2013	→
The press, press releases, and raising unwarranted expectations.	Wald NJ	—	2013	→
Turning of COGS moves forward findings for hormonally mediated cancers.	Sakoda LC et al.	—	2013	→