A genome-wide association study identifies novel risk loci for type 2 diabetes.
paper
Cited
Public
Unavailable
- Authors
- Sladek, Robert; Rocheleau, Ghislain; Rung, Johan; Dina, Christian; Shen, Lishuang; Serre, David; Boutin, Philippe; Vincent, Daniel; Belisle, Alexandre; Hadjadj, Samy; Balkau, Beverley; Heude, Barbara; Charpentier, Guillaume; Hudson, Thomas J; Montpetit, Alexandre; Pshezhetsky, Alexey V; Prentki, Marc; Posner, Barry I; Balding, David J; Meyre, David; Polychronakos, Constantin; Froguel, Philippe
- Year
- 2007
- Journal
- Nature
- PMID
- 17293876
- DOI
- 10.1038/nature05616
Type 2 diabetes mellitus results from the interaction of environmental factors with a combination of genetic variants, most of which were hitherto unknown. A systematic search for these variants was recently made possible by the development of high-density arrays that permit the genotyping of hundreds of thousands of polymorphisms. We tested 392,935 single-nucleotide polymorphisms in a French case-control cohort. Markers with the most significant difference in genotype frequencies between cases of type 2 diabetes and controls were fast-tracked for testing in a second cohort. This identified four loci containing variants that confer type 2 diabetes risk, in addition to confirming the known association with the TCF7L2 gene. These loci include a non-synonymous polymorphism in the zinc transporter SLC30A8, which is expressed exclusively in insulin-producing beta-cells, and two linkage disequilibrium blocks that contain genes potentially involved in beta-cell development or function (IDE-KIF11-HHEX and EXT2-ALX4). These associations explain a substantial portion of disease risk and constitute proof of principle for the genome-wide approach to the elucidation of complex genetic traits.
No figures extracted from this document.
No chunks — full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| 2026 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association. | Palaniappan LP et al. | — | 2026 | → |
| Correlative imaging reveals metal dyshomeostasis and altered zinc coordination environments in a pre-clinical Type 2 diabetes model. | Ellison G et al. | — | 2026 | → |
| Discovery of pyrimidine-based small activators of insulin degrading enzyme. | El Bakali J et al. | — | 2026 | → |
| High-Fat Diet-Fed Kcnq1 Mutant Mice Have Reduced Pancreatic β-Cell Mass via Gene-Environment Interaction. | Asahara SI et al. | — | 2026 | → |
| Interaction of serum zinc and copper status with fatty acid desaturases on incidence of type 2 diabetes in the EPIC-Potsdam study. | Prada M et al. | — | 2026 | → |
| Pancreatic β-cell turnover in health and disease. | Alcibahy Y et al. | — | 2026 | → |
| The transcription factor HHEX maintains glucocorticoid levels and protects adrenals from androgen-induced lipid depletion. | Dumontet T et al. | — | 2026 | → |
| 2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association. | Martin SS et al. | — | 2025 | → |
| A Genetic Clue to T2DM in Bangladesh: The <i>TCF7L2 rs12255372</i> (G/T) Variant. | Mahmood SA et al. | — | 2025 | → |
| Alternative cleavage and polyadenylation: key regulatory mechanisms in health and disease. | Zhang Y et al. | — | 2025 | → |
| A structural perspective of transmembrane transport of zinc by ZnT and ZIP transporters. | Xie Q et al. | — | 2025 | → |
| A Systematic Review of the Effect of Gene-Lifestyle Interactions on Metabolic-Disease-Related Traits in South Asian Populations. | Bineid MM et al. | — | 2025 | → |
| Changes in triglyceride-rich lipoprotein particle profiles in response to one-week on a low fat or Mediterranean diet by TCF7L2 rs7903146 genotype: a randomized crossover dietary intervention trial. | Lai CQ et al. | — | 2025 | → |
| Complete loss of SLC30A8 in humans improves glucose metabolism and beta cell function. | Lamarche LB et al. | — | 2025 | → |
| Construction of cynomolgus monkey type 2 diabetes models by combining genetic prediction model with high-energy diet. | Li P et al. | — | 2025 | → |
| Correlation between circulating microRNAs and vascular biomarkers in type 2 diabetes based upon physical activity: a biochemical analytic study. | Al-Rawaf HA et al. | — | 2025 | → |
| Diabetes in China: epidemiology, pathophysiology and multi-omics. | Jia W et al. | — | 2025 | → |
| Diabetes Mellitus: Exploring Biomarkers, Complications, and Therapeutic Strategies with a Spotlight on Cyanobacterial Bioactive Compounds - A Comprehensive Review. | Ahmad S et al. | — | 2025 | → |
| Diabetes mellitus polygenic risk scores: heterogeneity and clinical translation. | Ortega HI et al. | — | 2025 | → |
| Differences in insulin resistance biomarkers, but not on serum zinc concentration, among individuals with different SLC30A8 genotypes: analysis of the São Paulo population-based study (2015 ISA-Nutrition). | Duarte GBS et al. | — | 2025 | → |
| Dissection of type 2 diabetes: a genetic perspective. | Bonnefond A et al. | — | 2025 | → |
| DPP-IV and FAS inhibitory peptides: therapeutic alternative against diabesity. | Fabiola León-Galván M et al. | — | 2025 | → |
| Elevated PTPN3 expression in type 2 diabetes mellitus: Insights from genetic and experimental analyses. | Chen SY et al. | — | 2025 | → |
| Exploring Genetic Heterogeneity in Type 2 Diabetes Subtypes. | Timasheva Y et al. | — | 2025 | → |
| Exploring the shared genetic landscape of diabetes and cardiovascular disease: findings and future implications. | Lee H et al. | — | 2025 | → |
| From Human to Mouse and Back Again: Genetic and Genomic Ta(i)les of Islet Dysfunction in Type 2 Diabetes. | Kursawe R et al. | — | 2025 | → |
| Genetic Polymorphism of Zinc Transporter-8 Gene (SLC30A8), Serum Zinc Concentrations, and Proteome Profiles Related to Type 2 Diabetes in Elderly. | Sirivarasai J et al. | — | 2025 | → |
| Genetic risk predictions using deep learning models with summary data. | Wang A et al. | — | 2025 | → |
| Loss-of-function variant of SLC30A8 rs13266634 (C > T) protects against type 2 diabetes by stabilizing ZnT8: Insights from epidemiological and computational analyses. | Barman N et al. | — | 2025 | → |
| Loss of Slc39a5 in α-cells impairs glucose metabolism by chronically increasing glucagon. | Chen W et al. | — | 2025 | → |
| Medical and Nonmedical Applications of Synthetic Transmembrane Anion Transporters. | Rathnaweera UMC et al. | — | 2025 | → |
| metacp: a versatile software package for combining dependent or independent p-values. | Nikolitsa EK et al. | — | 2025 | → |
| Microcephaly with or without chorioretinopathy, lymphedema, or mental retardation associated with KIF11 pathogenic variant: case report and genotype-phenotype correlation analysis. | Peng J et al. | — | 2025 | → |
| Pharmacologic stimulation of insulin granule acidification increases β-cell zinc content and augments β-cell-targeted drug delivery. | Lee S et al. | — | 2025 | → |
| Polymorphisms Involved in Insulin Resistance and Metabolic Inflammation: Influence of Nutrients and Dietary Interventions. | Duarte GBS et al. | — | 2025 | → |
| Predicting Mutation-Disease Associations Through Protein Interactions Via Deep Learning. | Li X et al. | — | 2025 | → |
| Shared transcriptional regulators and network rewiring identify therapeutic targets linking type 2 diabetes mellitus and hypertension. | Norzagaray-Valenzuela CD et al. | — | 2025 | → |
| Significant Association Between Glucokinase Regulatory Protein Variants and Genetic and Metabolic Diseases. | Xu K et al. | — | 2025 | → |
| Synergistic therapeutic strategies for metabolic dysfunction-associated steatohepatitis and type 2 diabetes mellitus: molecular insights and clinical advances. | Zhu B | — | 2025 | → |
| The association between mixed exposure to per- and polyfluoroalkyl substances and the risk of diabetes. | Yu M et al. | — | 2025 | → |
| The diabetes gene Tcf7l2 organizes gene expression in the liver and regulates amino acid metabolism. | Krawczyk J et al. | — | 2025 | → |
| The Impact of Ancestry on Genome-Wide Association Studies. | Jones SC et al. | — | 2025 | → |
| Type 2 diabetes mellitus and zinc dysregulation: From basic and epidemiological evidence to interventions. | Martinez-Morata I et al. | — | 2025 | → |
| ZnTs: Key Regulators of Zn<sup>2+</sup> Homeostasis in Diseases. | Liu H et al. | — | 2025 | → |
| Zrt-Irt-like Proteins (ZIP) Family Zinc Transporters: Emerging Players in Pancreatic β Cell Function and Insulin Regulation. | Mitchell SB et al. | — | 2025 | → |
| 2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association. | Martin SS et al. | — | 2024 | → |
| Absence of <i>Slc39a14/Zip14</i> in mouse pancreatic beta cells results in hyperinsulinemia. | Hung YH et al. | — | 2024 | → |
| A double knockout for zinc transporter 8 and somatostatin in mice reveals their distinct roles in regulation of insulin secretion and obesity. | Yang Z et al. | — | 2024 | → |
| Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily. | Digles D et al. | — | 2024 | → |
| A novel chromone Schiff base as Zn<sup>2+</sup> turn-on fluorescent chemosensor in a mixed solution. | Yang W et al. | — | 2024 | → |
| Association between genetic polymorphisms and gestational diabetes mellitus susceptibility in a Chinese population. | Zeng Q et al. | — | 2024 | → |
| Association Study of <i>CACNA1D</i>, <i>KCNJ11</i>, <i>KCNQ1</i>, and <i>CACNA1E</i> Single-Nucleotide Polymorphisms with Type 2 Diabetes Mellitus. | Díaz-García JD et al. | — | 2024 | → |
| Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets. | Chen B et al. | — | 2024 | → |
| Development of a live cell assay for the zinc transporter ZnT8. | Azzollini L et al. | — | 2024 | → |
| Effect of Vitamin D on Retinoblastoma Protein in Prediabetic Individuals. | Hardatt D et al. | — | 2024 | → |
| From zinc homeostasis to disease progression: Unveiling the neurodegenerative puzzle. | Fan YG et al. | — | 2024 | → |
| Functional genetics reveals the contribution of delta opioid receptor to type 2 diabetes and beta-cell function. | Meulebrouck S et al. | — | 2024 | → |
| Gene therapy for polygenic or complex diseases. | Wu T et al. | — | 2024 | → |
| Genetic studies of type 2 diabetes, and microvascular complications of diabetes. | Imamura M et al. | — | 2024 | → |
| GRP94 is an IGF-1R chaperone and regulates beta cell death in diabetes. | Kim DS et al. | — | 2024 | → |
| IAPP - oligomerisation levels in plasma of people with type 2 diabetes. | Rehn F et al. | — | 2024 | → |
| Impact of the trans-ancestry polygenic risk score on type 2 diabetes risk, onset age and progression among population in Taiwan. | Wang SH et al. | — | 2024 | → |
| Insulin Resistance/Diabetes and Schizophrenia: Potential Shared Genetic Factors and Implications for Better Management of Patients with Schizophrenia. | Zhuo C et al. | — | 2024 | → |
| KIF11 UFMylation Maintains Photoreceptor Cilium Integrity and Retinal Homeostasis. | Ran J et al. | — | 2024 | → |
| Mitochondrial-derived peptides: Antidiabetic functions and evolutionary perspectives. | Kal S et al. | — | 2024 | → |
| Multiple genetic variants at the SLC30A8 locus affect local super-enhancer activity and influence pancreatic β-cell survival and function. | Hu M et al. | — | 2024 | → |
| Perspectives on genetic studies of type 2 diabetes from the genome-wide association studies era to precision medicine. | Imamura M et al. | — | 2024 | → |
| Risk prediction and interaction analysis using polygenic risk score of type 2 diabetes in a Korean population. | Song M et al. | — | 2024 | → |
| Single-housing-induced islet epigenomic changes are related to polymorphisms in diabetic KK mice. | Nammo T et al. | — | 2024 | → |
| Sulfation pathways in the maintenance of functional beta-cell mass and implications for diabetes. | Mueller JW et al. | — | 2024 | → |
| The hazards of genotype imputation when mapping disease susceptibility variants. | Lau W et al. | — | 2024 | → |
| The impact of CREBRF rs373863828 Pacific-variant on infant body composition. | Amitrano F et al. | — | 2024 | → |
| The Parasite-Derived Peptide, FhHDM-1, Selectively Modulates miRNA Expression in <i>β</i>-Cells to Prevent Apoptotic Pathways Induced by Proinflammatory Cytokines. | Camaya I et al. | — | 2024 | → |
| Anti-Islet Autoantibodies in Type 1 Diabetes. | Kawasaki E | — | 2023 | → |
| Association between Genotype and the Glycemic Response to an Oral Glucose Tolerance Test: A Systematic Review. | Bayer S et al. | — | 2023 | → |
| Association of HHEX and SLC30A8 Gene Polymorphisms with Gestational Diabetes Mellitus Susceptibility: A Meta-analysis. | Xie W et al. | — | 2023 | → |
| Association of <i>solute carrier family 30 A8 zinc transporter gene</i> variations with gestational diabetes mellitus risk in a Chinese population. | Zeng Q et al. | — | 2023 | → |
| Association of vitamin D levels and polymorphisms in vitamin D receptor with type 2 diabetes mellitus. | Alfaqih MA et al. | — | 2023 | → |
| Common Pathogenetic Pathways of Non-Alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus. | Giannopoulos CK et al. | — | 2023 | → |
| Comprehensive Diagnostic Criteria for MELAS Syndrome; a Case Study Involving an Elderly Patient With MT-TWm.5541C>T Mutation. | Wu G et al. | — | 2023 | → |
| Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn<sup>2+</sup>-releasing mechanism. | Zhang S et al. | — | 2023 | → |
| Current insights and emerging trends in early-onset type 2 diabetes. | Misra S et al. | — | 2023 | → |
| Deep Learning Framework for Complex Disease Risk Prediction Using Genomic Variations. | Alzoubi H et al. | — | 2023 | → |
| Developmental origins of diabetes mellitus: Environmental epigenomics and emerging patterns. | Zhu H et al. | — | 2023 | → |
| Effects of a genetic variant rs13266634 in the zinc transporter 8 gene (SLC30A8) on insulin and lipid levels before and after a high-fat mixed macronutrient tolerance test in U.S. adults. | Yang Z et al. | — | 2023 | → |
| Elucidation of HHEX in pancreatic endoderm differentiation using a human iPSC differentiation model. | Ito R et al. | — | 2023 | → |
| Genetic and epigenetic background of diabetic kidney disease. | Sandholm N et al. | — | 2023 | → |
| Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association. | Tsao CW et al. | — | 2023 | → |
| High-resolution analysis of the cytosolic Ca<sup>2+</sup> events in β cell collectives in situ. | Postić S et al. | — | 2023 | → |
| Human Exome Sequencing and Prospects for Predictive Medicine: Analysis of International Data and Own Experience. | Glotov OS et al. | — | 2023 | → |
| Identification of Potential Plant-Derived Pancreatic Beta-Cell-Directed Agents Using New Custom-Designed Screening Method: <i>Gymnema sylvestre</i> as an Example. | Al-Romaiyan A et al. | — | 2023 | → |
| Impact of an <i>SLC30A8</i> loss-of-function variant on the pancreatic distribution of zinc and manganese: laser ablation-ICP-MS and positron emission tomography studies in mice. | Firth G et al. | — | 2023 | → |
| Integrating Common Risk Factors with Polygenic Scores Improves the Prediction of Type 2 Diabetes. | Timasheva Y et al. | — | 2023 | → |
| Interactions between Bitter Taste Receptor Gene Variants and Dietary Intake Are Associated with the Incidence of Type 2 Diabetes Mellitus in Middle-Aged and Older Korean Adults. | Lee KW et al. | — | 2023 | → |
| Lean legacy, heavy heritage: family history of diabetes and its association with young adult body mass index. | Kowaleski-Jones L et al. | — | 2023 | → |
| Mechanisms of ag85a/b DNA vaccine conferred immunotherapy and recovery from Mycobacterium tuberculosis-induced injury. | Wang N et al. | — | 2023 | → |
| Modulation of Zinc Transporter Expressions by Additional Zinc in C2C12 Cells Cultured in a High Glucose Environment and in the Presence of Insulin or Interleukin-6. | Ruz M et al. | — | 2023 | → |
| Partners in diabetes epidemic: A global perspective. | Wang H et al. | — | 2023 | → |
| Pharmacological activation of insulin-degrading enzyme improves insulin secretion and glucose tolerance in diet-induced obese mice. | Sanz-González A et al. | — | 2023 | → |
| Precision Medicine in Type 2 Diabetes Mellitus: Utility and Limitations. | Galiero R et al. | — | 2023 | → |
| Probing the diabetes and colorectal cancer relationship using gene - environment interaction analyses. | Dimou N et al. | — | 2023 | → |
| Progress in genetics of type 2 diabetes and diabetic complications. | Shojima N et al. | — | 2023 | → |
| Roles of Matrix Metalloproteinases and Their Natural Inhibitors in Metabolism: Insights into Health and Disease. | Molière S et al. | — | 2023 | → |
| Screening properties of trend tests in genetic association studies. | Jiang Z et al. | — | 2023 | → |
| THADA inhibition in mice protects against type 2 diabetes mellitus by improving pancreatic β-cell function and preserving β-cell mass. | Zhang Y et al. | — | 2023 | → |
| Updates of precision medicine in type 2 diabetes. | Xia M et al. | — | 2023 | → |
| You are What You Drink? How Associations Between Profiles of Beverage Consumption and Type 2 Diabetes Risk are Mediated by Biomarker Networks. | Rose BD et al. | — | 2023 | → |
| Advances in electrospun nanofibrous membrane sensors for ion detection. | Wu L et al. | — | 2022 | → |
| Advances in multi-omics study of biomarkers of glycolipid metabolism disorder. | Fang X et al. | — | 2022 | → |
| Analysis of circRNA-mRNA expression profiles and functional enrichment in diabetes mellitus based on high throughput sequencing. | Zhao W et al. | — | 2022 | → |
| A Role for lncRNAs in Regulating Inflammatory and Autoimmune Responses Underlying Type 1 Diabetes. | Brodnicki TC | — | 2022 | → |
| Clinical Study on the Relationship between the SNP rs8192675 (C/C) Site of SLC2A2 Gene and the Hypoglycemic Effect of Metformin in Type 2 Diabetes. | Ye W et al. | — | 2022 | → |
| Comparative Analysis of Multiple GWAS Results Identifies Metabolic Pathways Associated with Resistance to <i>A. flavus</i> Infection and Aflatoxin Accumulation in Maize. | Warburton ML et al. | — | 2022 | → |
| Contribution of genetic variant identified in <i>HHEX</i> gene in the overweight Saudi patients confirmed with type 2 diabetes mellitus. | Alfaifi M | — | 2022 | → |
| Effect of TCF7L2 on the relationship between lifestyle factors and glycemic parameters: a systematic review. | Hosseinpour-Niazi S et al. | — | 2022 | → |
| Epigenome-wide association study of alcohol use disorder in five brain regions. | Zillich L et al. | — | 2022 | → |
| EXOC6 (Exocyst Complex Component 6) Is Associated with the Risk of Type 2 Diabetes and Pancreatic β-Cell Dysfunction. | Sulaiman N et al. | — | 2022 | → |
| Exposome and foetoplacental vascular dysfunction in gestational diabetes mellitus. | Valero P et al. | — | 2022 | → |
| Exposure to per- and polyfluoroalkyl substances (PFAS) and type 2 diabetes risk. | Roth K et al. | — | 2022 | → |
| Genetics of murine type 2 diabetes and comorbidities. | Lone IM et al. | — | 2022 | → |
| Genetics of type 2 diabetes mellitus in Indian and Global Population: A Review. | Joseph A et al. | — | 2022 | → |
| Genetics of Type 2 Diabetes: Past, Present, and Future. | Laakso M et al. | — | 2022 | → |
| Heart Disease and Stroke Statistics-2022 Update: A Report From the American Heart Association. | Tsao CW et al. | — | 2022 | → |
| Human islet amyloid polypeptide: A therapeutic target for the management of type 2 diabetes mellitus. | Roham PH et al. | — | 2022 | → |
| <i>ABCA1</i> C69T Gene Polymorphism Association with Dysglycemia in Saudi Prediabetic Adults. | Ajabnoor GMA et al. | — | 2022 | → |
| Identification of indole-based activators of insulin degrading enzyme. | Kraupner N et al. | — | 2022 | → |
| Importance of Heparan Sulfate Proteoglycans in Pancreatic Islets and β-Cells. | Takahashi I | — | 2022 | → |
| Insulin-degrading enzyme ablation in mouse pancreatic alpha cells triggers cell proliferation, hyperplasia and glucagon secretion dysregulation. | Merino B et al. | — | 2022 | → |
| Lack of ZnT8 protects pancreatic islets from hypoxia- and cytokine-induced cell death. | Karsai M et al. | — | 2022 | → |
| Methionine metabolism regulates pluripotent stem cell pluripotency and differentiation through zinc mobilization. | Sim EZ et al. | — | 2022 | → |
| Mitochondrial haplogroups have a better correlation to insulin requirement than nuclear genetic variants for type 2 diabetes mellitus in Taiwanese individuals. | Shen FC et al. | — | 2022 | → |
| Nontargeted and Targeted Metabolomic Profiling Reveals Novel Metabolite Biomarkers of Incident Diabetes in African Americans. | Chen ZZ et al. | — | 2022 | → |
| Novel diabetes gene discovery through comprehensive characterization and integrative analysis of longitudinal gene expression changes. | Chen HH et al. | — | 2022 | → |
| PhenGenVar: A User-Friendly Genetic Variant Detection and Visualization Tool for Precision Medicine. | Shin J et al. | — | 2022 | → |
| Prediction value of the genetic risk of type 2 diabetes on the amnestic mild cognitive impairment conversion to Alzheimer's disease. | Yang J et al. | — | 2022 | → |
| Stem Cell-Derived β Cells: A Versatile Research Platform to Interrogate the Genetic Basis of β Cell Dysfunction. | Bartolomé A | — | 2022 | → |
| TCF7L2 gene polymorphism in populations of f ive Siberian ethnic groups. | Tabikhanova LE et al. | — | 2022 | → |
| The effect of zinc supplementation on glucose homeostasis: a randomised double-blind placebo-controlled trial. | Attia JR et al. | — | 2022 | → |
| The Genetics of Type 2 Diabetes in Youth: Where We Are and the Road Ahead. | Srinivasan S et al. | — | 2022 | → |
| The Oxidative Balance Orchestrates the Main Keystones of the Functional Activity of Cardiomyocytes. | Bevere M et al. | — | 2022 | → |
| The Role of Zinc in Cardiovascular Disease. | Begum F et al. | — | 2022 | → |
| Type 2 Diabetes-Related Variants Influence the Risk of Developing Prostate Cancer: A Population-Based Case-Control Study and Meta-Analysis. | Sánchez-Maldonado JM et al. | — | 2022 | → |
| Unraveling the Influence of <i>HHEX</i> Risk Polymorphism rs7923837 on Multiple Sclerosis Pathogenesis. | González-Jiménez A et al. | — | 2022 | → |
| ZnT8 loss-of-function accelerates functional maturation of hESC-derived β cells and resists metabolic stress in diabetes. | Ma Q et al. | — | 2022 | → |
| A graph centrality-based approach for candidate gene prediction for type 1 diabetes. | Thummadi NB et al. | — | 2021 | → |
| A guide to plasma membrane solute carrier proteins. | Pizzagalli MD et al. | — | 2021 | → |
| Applications of iPSC-derived beta cells from patients with diabetes. | Maxwell KG et al. | — | 2021 | → |
| Association of HLA-B Gene Polymorphisms with Type 2 Diabetes in Pashtun Ethnic Population of Khyber Pakhtunkhwa, Pakistan. | Jan A et al. | — | 2021 | → |
| Association of type 2 diabetes mellitus and periodontal disease susceptibility with genome-wide association-identified risk variants in a Southeastern Brazilian population. | Cirelli T et al. | — | 2021 | → |
| Associations of transcription factor 7-Like 2 (<i>TCF7L2</i>) gene polymorphism in patients of type 2 diabetes mellitus from Khyber Pakhtunkhwa population of Pakistan. | Hameed T et al. | — | 2021 | → |
| Consequences for Pancreatic β-Cell Identity and Function of Unregulated Transcript Processing. | Ghiasi SM et al. | — | 2021 | → |
| CTNNA3 genetic polymorphism may be a new genetic signal of type 2 diabetes in the Chinese Han population: a case control study. | Zhang Y et al. | — | 2021 | → |
| Cutting the fat: advances and challenges in sleep apnoea genetics. | Wang H et al. | — | 2021 | → |
| Diabetes and Genetics: A Relationship Between Genetic Risk Alleles, Clinical Phenotypes and Therapeutic Approaches. | Sayed S et al. | — | 2021 | → |
| Disentangling the relationship between bone turnover and glucose homeostasis: A prospective, population-based twin study. | Dalgård C et al. | — | 2021 | → |
| Effect of serum zinc and copper levels on insulin secretion, insulin resistance and pancreatic β cell dysfunction in US adults: Findings from the National Health and Nutrition Examination Survey (NHANES) 2011-2012. | Kant R et al. | — | 2021 | → |
| Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group. | Jia T et al. | — | 2021 | → |
| Exploring the Epigenetic Regulatory Role of m6A-Associated SNPs in Type 2 Diabetes Pathogenesis. | Chen M et al. | — | 2021 | → |
| From virus to diabetes therapy: Characterization of a specific insulin-degrading enzyme inhibitor for diabetes treatment. | Nash Y et al. | — | 2021 | → |
| Genetic architecture of type 2 diabetes and its shared genetic component with low birth weight in African Americans. | Ruiz-Narváez EA | — | 2021 | → |
| Genetic risk factors associated with gestational diabetes in a multi-ethnic population. | Benny P et al. | — | 2021 | → |
| Genetics of Type 2 Diabetes: Opportunities for Precision Medicine: JACC Focus Seminar. | Kim DS et al. | — | 2021 | → |
| Genome-Wide Association Study of Body Weight Traits in Inner Mongolia Cashmere Goats. | Zhang L et al. | — | 2021 | → |
| Genotype-guided dietary supplementation in precision nutrition. | Gkouskou KK et al. | — | 2021 | → |
| Heart Disease and Stroke Statistics-2021 Update: A Report From the American Heart Association. | Virani SS et al. | — | 2021 | → |
| Hematopoietically-expressed homeobox protein HHEX regulates adipogenesis in preadipocytes. | Evseeva MN et al. | — | 2021 | → |
| Heparan sulfate promotes differentiation of white adipocytes to maintain insulin sensitivity and glucose homeostasis. | Matsuzawa T et al. | — | 2021 | → |
| Hepatocyte-Specific Co-Delivery of Zinc Ions and Plasmid DNA by Lactosylated Poly(1-vinylimidazole) for Suppression of Insulin Receptor Internalization. | Endo A et al. | — | 2021 | → |
| Heterologous Expression and Biochemical Characterization of the Human Zinc Transporter 1 (ZnT1) and Its Soluble C-Terminal Domain. | Cotrim CA et al. | — | 2021 | → |
| High levels of organochlorine pesticides in drinking water as a risk factor for type 2 diabetes: A study in north India. | Tyagi S et al. | — | 2021 | → |
| Human Pluripotent Stem Cells to Model Islet Defects in Diabetes. | Balboa D et al. | — | 2021 | → |
| Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants. | Hegron A et al. | — | 2021 | → |
| Impact of family history of diabetes on blood glucose, lipid levels and perinatal outcomes in pregnant women with gestational diabetes mellitus. | Zhou Y et al. | — | 2021 | → |
| Increasing the resolution and precision of psychiatric genome-wide association studies by re-imputing summary statistics using a large, diverse reference panel. | Chatzinakos C et al. | — | 2021 | → |
| Insights into the Dynamics of the Human Zinc Transporter ZnT8 by MD Simulations. | Sala D et al. | — | 2021 | → |
| Insulin granule biogenesis and exocytosis. | Omar-Hmeadi M et al. | — | 2021 | → |
| Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity. | Brestoff JR et al. | — | 2021 | → |
| Lessons in Organic Fluorescent Probe Discovery. | Wagh SB et al. | — | 2021 | → |
| Level of Organochlorine Pesticide in Prediabetic and Newly Diagnosed Diabetes Mellitus Patients with Varying Degree of Glucose Intolerance and Insulin Resistance among North Indian Population. | Tyagi S et al. | — | 2021 | → |
| Loss of Znt8 function in diabetes mellitus: risk or benefit? | Barragán-Álvarez CP et al. | — | 2021 | → |
| Mineralocorticoid receptors in the pathogenesis of insulin resistance and related disorders: from basic studies to clinical disease. | Jia G et al. | — | 2021 | → |
| Modulation of Insulin Sensitivity by Insulin-Degrading Enzyme. | González-Casimiro CM et al. | — | 2021 | → |
| Non-Coding RNA as Biomarkers for Type 2 Diabetes Development and Clinical Management. | Chi T et al. | — | 2021 | → |
| Novel EDGE encoding method enhances ability to identify genetic interactions. | Hall MA et al. | — | 2021 | → |
| Pancreatic β cell-selective zinc transporter 8 insufficiency accelerates diabetes associated with islet amyloidosis. | Xu J et al. | — | 2021 | → |
| Pharmacogenomics and Personalized Medicine in Type 2 Diabetes Mellitus: Potential Implications for Clinical Practice. | Venkatachalapathy P et al. | — | 2021 | → |
| Regulation of divalent metal ions to the aggregation and membrane damage of human islet amyloid polypeptide oligomers. | Wang Y et al. | — | 2021 | → |
| Relationship Between <i>KCNQ1</i> Polymorphism and Type 2 Diabetes Risk in Northwestern China. | Xu J et al. | — | 2021 | → |
| Relationship between the FTO Genotype and Early Chronic Kidney Disease in Type 2 Diabetes: The Mediating Role of Central Obesity, Hypertension, and High Albuminuria. | Marchetti J et al. | — | 2021 | → |
| Revisiting genome-wide association studies from statistical modelling to machine learning. | Sun S et al. | — | 2021 | → |
| Risk assessment of type 2 diabetes in northern China based on the logistic regression model. | Li C et al. | — | 2021 | → |
| Role of Wnt signaling pathways in type 2 diabetes mellitus. | Chen J et al. | — | 2021 | → |
| SLC30A8 gene polymorphism rs13266634 associated with increased risk for developing type 2 diabetes mellitus in Jordanian population. | Mashal S et al. | — | 2021 | → |
| Targeting Insulin-Degrading Enzyme in Insulin Clearance. | Leissring MA et al. | — | 2021 | → |
| The Association between Zinc and Copper Circulating Levels and Cardiometabolic Risk Factors in Adults: A Study of Qatar Biobank Data. | Kerkadi A et al. | — | 2021 | → |
| The Genetics of Diabetes: What We Can Learn from <i>Drosophila</i>. | Liguori F et al. | — | 2021 | → |
| The interplay among oxidative stress, brain insulin resistance and AMPK dysfunction contribute to neurodegeneration in type 2 diabetes and Alzheimer disease. | Barone E et al. | — | 2021 | → |
| The Role of <i>TCF7L2</i> in Type 2 Diabetes. | Del Bosque-Plata L et al. | — | 2021 | → |
| The Role of Molecular and Inflammatory Indicators in the Assessment of Cognitive Dysfunction in a Mouse Model of Diabetes. | Piatkowska-Chmiel I et al. | — | 2021 | → |
| The Role of the ATP-Binding Cassette A1 (ABCA1) in Human Disease. | Jacobo-Albavera L et al. | — | 2021 | → |
| The Role of Zinc Homeostasis in the Prevention of Diabetes Mellitus and Cardiovascular Diseases. | Tamura Y | — | 2021 | → |
| The role of zinc in the prevention and treatment of nonalcoholic fatty liver disease. | Barbara M et al. | — | 2021 | → |
| TIGER: The gene expression regulatory variation landscape of human pancreatic islets. | Alonso L et al. | — | 2021 | → |
| Transcription Factor-7-Like-2 (TCF7L2) in Atherosclerosis: A Potential Biomarker and Therapeutic Target. | Li J et al. | — | 2021 | → |
| Two decades since the fetal insulin hypothesis: what have we learned from genetics? | Hughes AE et al. | — | 2021 | → |
| Type 2 diabetes is associated with the MTNR1B gene, a genetic bridge between circadian rhythm and glucose metabolism, in a Turkish population. | Arikoglu H et al. | — | 2021 | → |
| Uncovering Evidence for Endocrine-Disrupting Chemicals That Elicit Differential Susceptibility through Gene-Environment Interactions. | Wallis DJ et al. | — | 2021 | → |
| Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP. | Lopez-Redondo M et al. | — | 2021 | → |
| Zinc transporters and their functional integration in mammalian cells. | Kambe T et al. | — | 2021 | → |
| ZnT8 Deficiency Protects From APAP-Induced Acute Liver Injury by Reducing Oxidative Stress Through Upregulating Hepatic Zinc and Metallothioneins. | Su W et al. | — | 2021 | → |
| A Bayesian analysis for investigating the association between rs13266634 polymorphism in SLC30A8 gene and type 2 diabetes. | Soltanian AR et al. | — | 2020 | → |
| A comprehensive review on zinc(II) complexes as anti-diabetic agents: The advances, scientific gaps and prospects. | Chukwuma CI et al. | — | 2020 | → |
| All thresholds of maternal hyperglycaemia from the WHO 2013 criteria for gestational diabetes identify women with a higher genetic risk for type 2 diabetes. | Hughes AE et al. | — | 2020 | → |
| A MicroRNA Linking Human Positive Selection and Metabolic Disorders. | Wang L et al. | — | 2020 | → |
| Analysis of the interaction effect of 48 SNPs and obesity on type 2 diabetes in Chinese Hans. | Liu J et al. | — | 2020 | → |
| Association Between Single Nucleotide Polymorphisms in <i>CDKAL1</i> and <i>HHEX</i> and Type 2 Diabetes in Chinese Population. | Li C et al. | — | 2020 | → |
| A Unifying Framework for Imputing Summary Statistics in Genome-Wide Association Studies. | Wu Y et al. | — | 2020 | → |
| Combined effect of interventions with pure or enriched mixtures of (poly)phenols and anti-diabetic medication in type 2 diabetes management: a meta-analysis of randomized controlled human trials. | Raimundo AF et al. | — | 2020 | → |
| Comparing the Efficacy of Supervised and Unsupervised Exercise Training on Glycaemic Control in Type 2 Diabetes: A Systematic Review. | Gajanand T et al. | — | 2020 | → |
| Computational determination of human PPARG gene: SNPs and prediction of their effect on protein functions of diabetic patients. | Mustafa HA et al. | — | 2020 | → |
| Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations. | Xue J et al. | — | 2020 | → |
| C-Terminal Domain of the Human Zinc Transporter hZnT8 Is Structurally Indistinguishable from Its Disease Risk Variant (R325W). | Ullah R et al. | — | 2020 | → |
| Disentangling the heterogeneity of adulthood-onset non-autoimmune diabetes: a little closer but lot more to do. | Trischitta V et al. | — | 2020 | → |
| Drivers for the comorbidity of type 2 diabetes mellitus and epilepsy: A scoping review. | Shlobin NA et al. | — | 2020 | → |
| Early pregnancy dyslipidemia is associated with placental DNA methylation at loci relevant for cardiometabolic diseases. | Ouidir M et al. | — | 2020 | → |
| From Genetic Association to Molecular Mechanisms for Islet-cell Dysfunction in Type 2 Diabetes. | Mattis KK et al. | — | 2020 | → |
| Functional Genomics in Pancreatic β Cells: Recent Advances in Gene Deletion and Genome Editing Technologies for Diabetes Research. | Hu M et al. | — | 2020 | → |
| Genetic predisposition in type 2 diabetes: A promising approach toward a personalized management of diabetes. | Sirdah MM et al. | — | 2020 | → |
| Genetics Insights in the Relationship Between Type 2 Diabetes and Coronary Heart Disease. | Goodarzi MO et al. | — | 2020 | → |
| Genetics of type 2 diabetes and coronary artery disease and their associations with twelve cardiometabolic traits in the United Arab Emirates population. | Osman W et al. | — | 2020 | → |
| Genetic Studies of Gestational Diabetes and Glucose Metabolism in Pregnancy. | Powe CE et al. | — | 2020 | → |
| Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study. | Cai L et al. | — | 2020 | → |
| Heart Disease and Stroke Statistics-2020 Update: A Report From the American Heart Association. | Virani SS et al. | — | 2020 | → |
| "H" for Heterogeneity in the Algorithm for Type 2 Diabetes Management. | Silvia P et al. | — | 2020 | → |
| Higher Plasma Sclerostin and Lower Wnt Signaling Gene Expression in White Adipose Tissue of Prediabetic South Asian Men Compared with White Caucasian Men. | Janssen LGM et al. | — | 2020 | → |
| Human Physiology of Genetic Defects Causing Beta-cell Dysfunction. | Kettunen JLT et al. | — | 2020 | → |
| Insights into pancreatic islet cell dysfunction from type 2 diabetes mellitus genetics. | Krentz NAJ et al. | — | 2020 | → |
| Insights into the structure-function relationship of both wild and mutant zinc transporter ZnT8 in human: a computational structural biology approach. | Gupta MK et al. | — | 2020 | → |
| In Vivo Reporter Assays Uncover Changes in Enhancer Activity Caused by Type 2 Diabetes-Associated Single Nucleotide Polymorphisms. | Eufrásio A et al. | — | 2020 | → |
| <i>SLC30A8, CDKAL1, TCF7L2, KCNQ1</i> and <i>IGF2BP2</i> are Associated with Type 2 Diabetes Mellitus in Iranian Patients. | Vatankhah Yazdi K et al. | — | 2020 | → |
| KLF14 inhibits osteogenic differentiation of human bone marrow mesenchymal stem cells by downregulating WNT3A. | Weng J et al. | — | 2020 | → |
| Low-density lipoprotein receptor-related protein 6-mediated signaling pathways and associated cardiovascular diseases: diagnostic and therapeutic opportunities. | Kang S | — | 2020 | → |
| No correlation between the variants of exostosin 2 gene and type 2 diabetes in Burkina Faso population. | Ouedraogo SY et al. | — | 2020 | → |
| Nutrient consumption-dependent association of a glucagon-like peptide-1 receptor gene polymorphism with insulin secretion. | Nishiya Y et al. | — | 2020 | → |
| Obesity, unfavourable lifestyle and genetic risk of type 2 diabetes: a case-cohort study. | Schnurr TM et al. | — | 2020 | → |
| [Partially French Canadians are susceptible to increased cardiovascular risk factors: A population-based retrospective cohort study]. | Daccache J et al. | — | 2020 | → |
| Pathogenic variants in actionable MODY genes are associated with type 2 diabetes. | Bonnefond A et al. | — | 2020 | → |
| Pharmacogenetics of Type 2 Diabetes-Progress and Prospects. | Nasykhova YA et al. | — | 2020 | → |
| Potential positive and negative consequences of ZnT8 inhibition. | Syring KE et al. | — | 2020 | → |
| Quantitative, High-Throughput Assays for Proteolytic Degradation of Amylin. | Suire CN et al. | — | 2020 | → |
| Secretory Autophagy and Its Relevance in Metabolic and Degenerative Disease. | Gonzalez CD et al. | — | 2020 | → |
| Serum biomarkers from cell-based assays for AhRL and MIS strongly predicted the future development of diabetes in a large community-based prospective study in Korea. | Lee HK et al. | — | 2020 | → |
| Solute Carrier Transporters as Potential Targets for the Treatment of Metabolic Disease. | Schumann T et al. | — | 2020 | → |
| Structure/Function Analysis of human ZnT8 (SLC30A8): A Diabetes Risk Factor and Zinc Transporter. | Daniels MJ et al. | — | 2020 | → |
| Systematic Comparison of Vesicular Targeting Signals Leads to the Development of Genetically Encoded Vesicular Fluorescent Zn<sup>2+</sup> and pH Sensors. | Pratt EPS et al. | — | 2020 | → |
| Systematic Review of Polygenic Risk Scores for Type 1 and Type 2 Diabetes. | Padilla-Martínez F et al. | — | 2020 | → |
| Targeting Glycoproteins as a therapeutic strategy for diabetes mellitus and its complications. | Naseri R et al. | — | 2020 | → |
| The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals. | Cao Y et al. | — | 2020 | → |
| Therapeutic potential of mesenchymal stem cells in treating both types of diabetes mellitus and associated diseases. | Goenka V et al. | — | 2020 | → |
| Thermally Stable Fluorogenic Zn(II) Sensor Based on a Bis(benzimidazole)pyridine-Linked Phenyl-Silsesquioxane Polymer. | Lenora CU et al. | — | 2020 | → |
| The role of genetics and epigenetics in the pathogenesis of gestational diabetes mellitus. | Rosik J et al. | — | 2020 | → |
| The role of KLF14 in multiple disease processes. | Chen X et al. | — | 2020 | → |
| The Role of Zinc and Copper in Insulin Resistance and Diabetes Mellitus. | Bjørklund G et al. | — | 2020 | → |
| Why and how to investigate the role of protein phosphorylation in ZIP and ZnT zinc transporter activity and regulation. | Thingholm TE et al. | — | 2020 | → |
| A CRISPR/Cas9 genome editing pipeline in the EndoC-βH1 cell line to study genes implicated in beta cell function. | Grotz AK et al. | — | 2019 | → |
| An atomistic view of the YiiP structural changes upon zinc(II) binding. | Sala D et al. | — | 2019 | → |
| An Exploratory Association Analysis of the Insulin Gene Region With Diabetes Mellitus in Two Dog Breeds. | Hess R et al. | — | 2019 | → |
| An in vivo screen for neuronal genes involved in obesity identifies Diacylglycerol kinase as a regulator of insulin secretion. | Trinh I et al. | — | 2019 | → |
| Association of transcription factor 7-like 2 (TCF7L2) gene polymorphism with type 2 diabetes mellitus in Chinese Korean ethnicity population. | Zhou KC et al. | — | 2019 | → |
| Association of vascular endothelial growth factor expression and polymorphisms with the risk of gestational diabetes mellitus. | Dong PP | — | 2019 | → |
| A structural overview of the zinc transporters in the cation diffusion facilitator family. | Cotrim CA et al. | — | 2019 | → |
| Benefits and limitations of genome-wide association studies. | Tam V et al. | — | 2019 | → |
| Completing the genetic spectrum influencing coronary artery disease: from germline to somatic variation. | Patel AP et al. | — | 2019 | → |
| Contribution of rare coding mutations in CD36 to type 2 diabetes and cardio-metabolic complications. | Meyre D et al. | — | 2019 | → |
| Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production. | Mao Z et al. | — | 2019 | → |
| Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress. | Merriman C et al. | — | 2019 | → |
| Evidence that Evolution of the Diabetes Susceptibility Gene SLC30A8 that Encodes the Zinc Transporter ZnT8 Drives Variations in Pancreatic Islet Zinc Content in Multiple Species. | Bosma KJ et al. | — | 2019 | → |
| Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. | Flannick J et al. | — | 2019 | → |
| From Pre-Diabetes to Diabetes: Diagnosis, Treatments and Translational Research. | Khan RMM et al. | — | 2019 | → |
| Genetic, Functional, and Immunological Study of ZnT8 in Diabetes. | Huang Q et al. | — | 2019 | → |
| GWAS of Behavioral Traits. | Mehta D et al. | — | 2019 | → |
| Habenular TCF7L2 links nicotine addiction to diabetes. | Duncan A et al. | — | 2019 | → |
| Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association. | Benjamin EJ et al. | — | 2019 | → |
| HHEX gene polymorphisms and type 2 diabetes mellitus: A case-control report from Iran. | Galavi H et al. | — | 2019 | → |
| Identification and characterization of differentially expressed genes in Type 2 Diabetes using in silico approach. | Gupta MK et al. | — | 2019 | → |
| Improving Imputation Accuracy by Inferring Causal Variants in Genetic Studies. | Wu Y et al. | — | 2019 | → |
| Increased Expression of Lipid Metabolism Genes in Early Stages of Wooden Breast Links Myopathy of Broilers to Metabolic Syndrome in Humans. | Lake JA et al. | — | 2019 | → |
| Interaction of amylin species with transition metals and membranes. | Alghrably M et al. | — | 2019 | → |
| Ion Transporters, Channelopathies, and Glucose Disorders. | Demirbilek H et al. | — | 2019 | → |
| <i>TCF7L2</i> Expression Is Regulated by Cell Differentiation and Overfeeding in Human Adipose Tissue. | Justesen L et al. | — | 2019 | → |
| Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension. | Baron M et al. | — | 2019 | → |
| Loss of ZnT8 function protects against diabetes by enhanced insulin secretion. | Dwivedi OP et al. | — | 2019 | → |
| Maintenance of Intestinal Epithelial Homeostasis by Zinc Transporters. | Ohashi W et al. | — | 2019 | → |
| Modelling the endocrine pancreas in health and disease. | Bakhti M et al. | — | 2019 | → |
| Pancreatic β-cell-specific deletion of insulin-degrading enzyme leads to dysregulated insulin secretion and β-cell functional immaturity. | Fernández-Díaz CM et al. | — | 2019 | → |
| PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity. | Jang I et al. | — | 2019 | → |
| Postprandial Insulin Response and Clearance Among Black and White Women: The Federal Women's Study. | Chung ST et al. | — | 2019 | → |
| Precision Medicine in Non Communicable Diseases. | Hasanzad M et al. | — | 2019 | → |
| Precision medicine in type 2 diabetes. | Prasad RB et al. | — | 2019 | → |
| Recent advances and perspectives in next generation sequencing application to the genetic research of type 2 diabetes. | Nasykhova YA et al. | — | 2019 | → |
| Role of metabolic syndrome and its components as mediators of the genetic effect on type 2 diabetes: A family-based study in China. | Song J et al. | — | 2019 | → |
| Sequence variants associating with urinary biomarkers. | Benonisdottir S et al. | — | 2019 | → |
| Setting the Stage for Islet Autoimmunity in Type 2 Diabetes: Obesity-Associated Chronic Systemic Inflammation and Endoplasmic Reticulum (ER) Stress. | Brooks-Worrell BM et al. | — | 2019 | → |
| Targeting the Zinc Transporter ZIP7 in the Treatment of Insulin Resistance and Type 2 Diabetes. | Adulcikas J et al. | — | 2019 | → |
| The association of TNF-α -308G/A and -238G/A polymorphisms with type 2 diabetes mellitus: a meta-analysis. | Guo X et al. | — | 2019 | → |
| The Contribution of Low-Frequency and Rare Coding Variation to Susceptibility to Type 2 Diabetes. | Flannick J | — | 2019 | → |
| The epithelial zinc transporter ZIP10 epigenetically regulates human epidermal homeostasis by modulating histone acetyltransferase activity. | Bin BH et al. | — | 2019 | → |
| THE EXPOSOME IN HUMAN EVOLUTION: FROM DUST TO DIESEL. | Trumble BC et al. | — | 2019 | → |
| The <i>TCF7L2</i> Locus: A Genetic Window Into the Pathogenesis of Type 1 and Type 2 Diabetes. | Grant SFA | — | 2019 | → |
| The Role of De Novo Noncoding Regulatory Mutations in Neurodevelopmental Disorders. | Turner TN et al. | — | 2019 | → |
| The variant at TGFBRAP1 is significantly associated with type 2 diabetes mellitus and affects diabetes-related miRNA expression. | Yang S et al. | — | 2019 | → |
| The zinc transporter Slc39a5 controls glucose sensing and insulin secretion in pancreatic β-cells via Sirt1- and Pgc-1α-mediated regulation of Glut2. | Wang X et al. | — | 2019 | → |
| The zinc transporter Zip14 (SLC39a14) affects Beta-cell Function: Proteomics, Gene expression, and Insulin secretion studies in INS-1E cells. | Maxel T et al. | — | 2019 | → |
| Type 2 Diabetes-Associated Genetic Polymorphisms as Potential Disease Predictors. | Witka BZ et al. | — | 2019 | → |
| Validation of Identified Susceptible Gene Variants for New-Onset Diabetes in Renal Transplant Recipients. | Hwang HS et al. | — | 2019 | → |
| What has zinc transporter 8 autoimmunity taught us about type 1 diabetes? | Williams CL et al. | — | 2019 | → |
| Zinc and its regulators in pancreas. | Zhao T et al. | — | 2019 | → |
| ZnT8 Haploinsufficiency Impacts MIN6 Cell Zinc Content and β-Cell Phenotype via ZIP-ZnT8 Coregulation. | Lawson R et al. | — | 2019 | → |
| A biomimetic approach to conjugate vitamin B<sub>6</sub> cofactor with the lysozyme cocooned fluorescent AuNCs and its application in turn-on sensing of zinc(II) in environmental and biological samples. | Bothra S et al. | — | 2018 | → |
| A candidate functional SNP rs7074440 in TCF7L2 alters gene expression through C-FOS in hepatocytes. | Piao X et al. | — | 2018 | → |
| A genetic variant in SLC30A2 causes breast dysfunction during lactation by inducing ER stress, oxidative stress and epithelial barrier defects. | Lee S et al. | — | 2018 | → |
| An active fluorescent probe based on aggregation-induced emission for intracellular bioimaging of Zn<sup>2+</sup> and tracking of interactions with single-stranded DNA. | Wen X et al. | — | 2018 | → |
| A novel chromone and rhodamine derivative as fluorescent probe for the detection of Zn(II) and Al(III) based on two different mechanisms. | Pang BJ et al. | — | 2018 | → |
| Association Between SLC30A8 rs13266634 Polymorphism and Risk of T2DM and IGR in Chinese Population: A Systematic Review and Meta-Analysis. | Dong F et al. | — | 2018 | → |
| Association of GCKR rs780094 polymorphism with circulating lipid levels in type 2 diabetes and hyperuricemia in Uygur Chinese. | Wang L et al. | — | 2018 | → |
| Association of polymorphisms in LEPR with type 2 diabetes and related metabolic traits in a Chinese population. | Zhang L et al. | — | 2018 | → |
| A variant of GRK5 is associated with the therapeutic efficacy of repaglinide in Chinese Han patients with type 2 diabetes mellitus. | Shang Z et al. | — | 2018 | → |
| Catalytic Mechanism of Amyloid-β Peptide Degradation by Insulin Degrading Enzyme: Insights from Quantum Mechanics and Molecular Mechanics Style Møller-Plesset Second Order Perturbation Theory Calculation. | Lai R et al. | — | 2018 | → |
| Cohort Profile: Genetics of Diabetes Audit and Research in Tayside Scotland (GoDARTS). | Hébert HL et al. | — | 2018 | → |
| Complex patterns of direct and indirect association between the transcription Factor-7 like 2 gene, body mass index and type 2 diabetes diagnosis in adulthood in the Hispanic Community Health Study/Study of Latinos. | Fernández-Rhodes L et al. | — | 2018 | → |
| Contribution of Genetic Factors to Lower DHEAS in Patients with Rheumatoid Arthritis. | Vernerova L et al. | — | 2018 | → |
| Detection of SNPs of T2DM susceptibility genes by a ligase detection reaction-fluorescent nanosphere technique. | Chen Y et al. | — | 2018 | → |
| DNA methylation in the pathogenesis of type 2 diabetes in humans. | Davegårdh C et al. | — | 2018 | → |
| Effect of smoking on the association of HHEX (rs5015480) with diabetes among Korean women and heavy smoking men. | Sull JW et al. | — | 2018 | → |
| Empirical Comparisons of Different Statistical Models To Identify and Validate Kernel Row Number-Associated Variants from Structured Multi-parent Mapping Populations of Maize. | Yang J et al. | — | 2018 | → |
| Evaluation of the roles of the cytosolic N-terminus and His-rich loop of ZNT proteins using ZNT2 and ZNT3 chimeric mutants. | Fukue K et al. | — | 2018 | → |
| Fetuin-A levels and risk of type 2 diabetes mellitus: a systematic review and meta-analysis. | Guo VY et al. | — | 2018 | → |
| From SNPs to pathways: Biological interpretation of type 2 diabetes (T2DM) genome wide association study (GWAS) results. | Cirillo E et al. | — | 2018 | → |
| Genetic Approaches to the Study of Gene Variants and Their Impact on the Pathophysiology of Type 2 Diabetes. | Szabo M et al. | — | 2018 | → |
| Genetic architecture: the shape of the genetic contribution to human traits and disease. | Timpson NJ et al. | — | 2018 | → |
| Genetic Drivers of Pancreatic Islet Function. | Keller MP et al. | — | 2018 | → |
| Genetics of Exfoliation Syndrome. | Aung T et al. | — | 2018 | → |
| Genetic variants of gestational diabetes mellitus: a study of 112 SNPs among 8722 women in two independent populations. | Ding M et al. | — | 2018 | → |
| Genetic variation of the transcription factor GATA3, not STAT4, is associated with the risk of type 2 diabetes in the Bangladeshi population. | Huda N et al. | — | 2018 | → |
| Glutathione S-transferase genes and the risk of type 2 diabetes mellitus: Role of sexual dimorphism, gene-gene and gene-smoking interactions in disease susceptibility. | Azarova I et al. | — | 2018 | → |
| GRP94 Is an Essential Regulator of Pancreatic β-Cell Development, Mass, and Function in Male Mice. | Kim DS et al. | — | 2018 | → |
| Heart Disease and Stroke Statistics-2018 Update: A Report From the American Heart Association. | Benjamin EJ et al. | — | 2018 | → |
| Hematopoietically expressed homeobox gene is associated with type 2 diabetes in KK Cg-A<sup>y</sup>/J mice and a Taiwanese Han Chinese population. | Lu CC et al. | — | 2018 | → |
| Highly specific monoclonal antibodies for allosteric inhibition and immunodetection of the human pancreatic zinc transporter ZnT8. | Merriman C et al. | — | 2018 | → |
| High-Throughput Approaches onto Uncover (Epi)Genomic Architecture of Type 2 Diabetes. | Dziewulska A et al. | — | 2018 | → |
| How cellular Zn<sup>2+</sup> signaling drives physiological functions. | Levaot N et al. | — | 2018 | → |
| IAPP/amylin and β-cell failure: implication of the risk factors of type 2 diabetes. | Kanatsuka A et al. | — | 2018 | → |
| Identification of four genes as novel susceptibility loci for early-onset type 2 diabetes mellitus, metabolic syndrome, or hyperuricemia. | Yamada Y et al. | — | 2018 | → |
| Impact of KCNQ1, CDKN2A/2B, CDKAL1, HHEX, MTNR1B, SLC30A8, TCF7L2, and UBE2E2 on risk of developing type 2 diabetes in Thai population. | Plengvidhya N et al. | — | 2018 | → |
| Impact of variants on type-2 diabetes risk genes identified through genomewide association studies in polycystic ovary syndrome: a case-control study. | Ezzidi I et al. | — | 2018 | → |
| Interaction between a variant of CDKN2A/B-gene with lifestyle factors in determining dyslipidemia and estimated cardiovascular risk: A step toward personalized nutrition. | Mehramiz M et al. | — | 2018 | → |
| Interaction Between Nutrition and Metabolism. | Barrouin-Melo SM et al. | — | 2018 | → |
| Jointly Modelling Single Nucleotide Polymorphisms With Longitudinal and Time-to-Event Trait: An Application to Type 2 Diabetes and Fasting Plasma Glucose. | Canouil M et al. | — | 2018 | → |
| Metabolic pathways at the crossroads of diabetes and inborn errors. | Goetzman ES et al. | — | 2018 | → |
| Metformin Alters Upper Small Intestinal Microbiota that Impact a Glucose-SGLT1-Sensing Glucoregulatory Pathway. | Bauer PV et al. | — | 2018 | → |
| Method to estimate the approximate samples size that yield a certain number of significant GWAS signals in polygenic traits. | Bacanu SA et al. | — | 2018 | → |
| Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4. | Eriksson O et al. | — | 2018 | → |
| Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men. | Rorsman P et al. | — | 2018 | → |
| Pathophysiology of Type 2 Diabetes in Koreans. | Kwak SH et al. | — | 2018 | → |
| Physiologic Interpretation of GWAS Signals for Type 2 Diabetes. | Watanabe RM | — | 2018 | → |
| pKWmEB: integration of Kruskal-Wallis test with empirical Bayes under polygenic background control for multi-locus genome-wide association study. | Ren WL et al. | — | 2018 | → |
| Precision medicine in diabetes prevention, classification and management. | Xie F et al. | — | 2018 | → |
| Progress in defining the genetic contribution to type 2 diabetes susceptibility. | Morris AP | — | 2018 | → |
| Prolonged stimulation of insulin release from MIN6 cells causes zinc depletion and loss of β-cell markers. | Lawson R et al. | — | 2018 | → |
| Role of Zinc Homeostasis in the Pathogenesis of Diabetes and Obesity. | Fukunaka A et al. | — | 2018 | → |
| Sensors for measuring subcellular zinc pools. | Chabosseau P et al. | — | 2018 | → |
| Single Nucleotide Polymorphism at +276 G>T of the Adiponectin Gene and Plasma Adiponectin Level in Myanmar Type 2 Diabetic Patients. | Yu KT et al. | — | 2018 | → |
| SLC30A8 polymorphism and BMI complement HLA-A*24 as risk factors for poor graft function in islet allograft recipients. | Balke EM et al. | — | 2018 | → |
| SLC30A family expression in the pancreatic islets of humans and mice: cellular localization in the β-cells. | Cai Y et al. | — | 2018 | → |
| Targeting MicroRNA-143 Leads to Inhibition of Glioblastoma Tumor Progression. | Lozada-Delgado EL et al. | — | 2018 | → |
| T Cell Factor 7 (TCF7)/TCF1 Feedback Controls Osteocalcin Signaling in Brown Adipocytes Independent of the Wnt/β-Catenin Pathway. | Li Q et al. | — | 2018 | → |
| Teasing Diabetes Apart, One Locus at a Time. | Leslie RD et al. | — | 2018 | → |
| The core sequence of PIF competes for insulin/amyloid β in insulin degrading enzyme: potential treatment for Alzheimer's disease. | Hayrabedyan S et al. | — | 2018 | → |
| The C-terminal cytosolic domain of the human zinc transporter ZnT8 and its diabetes risk variant. | Parsons DS et al. | — | 2018 | → |
| The Extending Spectrum of NPC1-Related Human Disorders: From Niemann-Pick C1 Disease to Obesity. | Lamri A et al. | — | 2018 | → |
| The pathogenetic role of β-cell mitochondria in type 2 diabetes. | Fex M et al. | — | 2018 | → |
| The α-cell in diabetes mellitus. | Gromada J et al. | — | 2018 | → |
| Transcriptional regulation of metabolism in disease: From transcription factors to epigenetics. | Hawkins LJ et al. | — | 2018 | → |
| Type 2 Diabetes Mellitus and Cardiovascular Disease: Genetic and Epigenetic Links. | De Rosa S et al. | — | 2018 | → |
| Type 2 diabetes mellitus: distribution of genetic markers in Kazakh population. | Sikhayeva N et al. | — | 2018 | → |
| Variants of CDKAL1 rs7754840 (G/C) and CDKN2A/2B rs10811661 (C/T) with gestational diabetes: insignificant association. | Noury AE et al. | — | 2018 | → |
| Zinc deficiency and cellular oxidative stress: prognostic implications in cardiovascular diseases. | Choi S et al. | — | 2018 | → |
| Zinc stimulates glucose oxidation and glycemic control by modulating the insulin signaling pathway in human and mouse skeletal muscle cell lines. | Norouzi S et al. | — | 2018 | → |
| Zinc Supplementation Does Not Affect Glucagon Response to Intravenous Glucose and Insulin Infusion in Patients with Well-Controlled Type 2 Diabetes. | Pérez A et al. | — | 2018 | → |
| Zinc transporter 8 autoantibodies (ZnT8-ab) are associated with higher prevalence of multiple diabetes-related autoantibodies in adults with type 1 diabetes. | Rogowicz-Frontczak A et al. | — | 2018 | → |
| Zinc Transporters and the Progression of Breast Cancers. | Takatani-Nakase T | — | 2018 | → |
| ZnT8 Arg325Trp polymorphism influences zinc transporter expression and cytokine production in PBMCs from patients with diabetes. | Giacconi R et al. | — | 2018 | → |
| A benzimidazole-based chemodosimeter for the fluorometric detection of Zn and Cu via 1,5 proton shifts and C-N bond cleavage. | Basu Roy S et al. | — | 2017 | → |
| A common rs7903146 variant of the transcription factor 7-like 2 gene is associated with type 2 diabetes mellitus and fasting glucose in a Taiwanese population. | Hsiao TJ et al. | — | 2017 | → |
| Additional Evidence Supports Association of Common Variants in COL11A1 with Increased Risk of Hip Osteoarthritis Susceptibility. | Wang J et al. | — | 2017 | → |
| A novel role for the Krüppel-like factor 14 on macrophage inflammatory response and atherosclerosis development. | Wei X et al. | — | 2017 | → |
| A prospective study of dietary and supplemental zinc intake and risk of type 2 diabetes depending on genetic variation in <i>SLC30A8</i>. | Drake I et al. | — | 2017 | → |
| Association between serum osteocalcin and glucose/lipid metabolism in Chinese Han and Uygur populations with type 2 diabetes mellitus in Xinjiang: two cross-sectional studies. | Chen Y et al. | — | 2017 | → |
| Association of a type 2 diabetes genetic risk score with insulin secretion modulated by insulin sensitivity among Chinese Hans. | Kong X et al. | — | 2017 | → |
| Classical Statistics and Statistical Learning in Imaging Neuroscience. | Bzdok D | — | 2017 | → |
| Comparative study of serum 8-hydroxydeoxy-guanosine levels among healthy offspring of diabetic and non-diabetic parents. | Hasan M et al. | — | 2017 | → |
| Design of new traditional Chinese medicine herbal formulae for treatment of type 2 diabetes mellitus based on network pharmacology. | Hu RF et al. | — | 2017 | → |
| Differential cytolocation and functional assays of the two major human SLC30A8 (ZnT8) isoforms. | Carvalho S et al. | — | 2017 | → |
| Disturbance of zinc and glucose homeostasis by methyl tert-butyl ether (MTBE); evidence for type 2 diabetes. | Saeedi A et al. | — | 2017 | → |
| Diversity and inclusion in genomic research: why the uneven progress? | Bentley AR et al. | — | 2017 | → |
| Early maternal separation induces preference for sucrose and aspartame associated with increased blood glucose and hyperactivity. | Aya-Ramos L et al. | — | 2017 | → |
| Exploring the Association Between Demographics, SLC30A8 Genotype, and Human Islet Content of Zinc, Cadmium, Copper, Iron, Manganese and Nickel. | Wong WP et al. | — | 2017 | → |
| Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion. | Ndiaye FK et al. | — | 2017 | → |
| Gene-Diet Interaction and Precision Nutrition in Obesity. | Heianza Y et al. | — | 2017 | → |
| Gene expression signature: a powerful approach for drug discovery in diabetes. | Sithara S et al. | — | 2017 | → |
| Genetic association studies in cardiovascular diseases: Do we have enough power? | Auer PL et al. | — | 2017 | → |
| Genetic determinants of circulating GIP and GLP-1 concentrations. | Almgren P et al. | — | 2017 | → |
| Genetic variants of increased waist circumference in psychosis. | Hukic DS et al. | — | 2017 | → |
| Genetic Variations as Modifying Factors to Dietary Zinc Requirements-A Systematic Review. | Day KJ et al. | — | 2017 | → |
| Genome-wide association studies and meta-analysis reveal novel quantitative trait loci and pleiotropic loci for swine head-related traits. | Chen H et al. | — | 2017 | → |
| Genomics of Islet (Dys)function and Type 2 Diabetes. | Lawlor N et al. | — | 2017 | → |
| GWAR: robust analysis and meta-analysis of genome-wide association studies. | Dimou NL et al. | — | 2017 | → |
| Human genetics as a model for target validation: finding new therapies for diabetes. | Thomsen SK et al. | — | 2017 | → |
| hZnT8 (Slc30a8) Transgenic Mice That Overexpress the R325W Polymorph Have Reduced Islet Zn2+ and Proinsulin Levels, Increased Glucose Tolerance After a High-Fat Diet, and Altered Levels of Pancreatic Zinc Binding Proteins. | Li L et al. | — | 2017 | → |
| Identification of five genetic variants as novel determinants of type 2 diabetes mellitus in Japanese by exome-wide association studies. | Yamada Y et al. | — | 2017 | → |
| Identifying and mitigating batch effects in whole genome sequencing data. | Tom JA et al. | — | 2017 | → |
| IFITM3, TLR3, and CD55 Gene SNPs and Cumulative Genetic Risks for Severe Outcomes in Chinese Patients With H7N9/H1N1pdm09 Influenza. | Lee N et al. | — | 2017 | → |
| Impact of Labile Zinc on Heart Function: From Physiology to Pathophysiology. | Turan B et al. | — | 2017 | → |
| Importance of Zinc Transporter 8 Autoantibody in the Diagnosis of Type 1 Diabetes in Latin Americans. | Gomes KF et al. | — | 2017 | → |
| Inositol phosphates and phosphoinositides activate insulin-degrading enzyme, while phosphoinositides also mediate binding to endosomes. | Song ES et al. | — | 2017 | → |
| Insulin Resistance and Mitochondrial Dysfunction. | Gonzalez-Franquesa A et al. | — | 2017 | → |
| Interaction of BDNF rs6265 variants and energy and protein intake in the risk for glucose intolerance and type 2 diabetes in middle-aged adults. | Daily JW et al. | — | 2017 | → |
| Investigation of miRNA-binding site variants and risk of gestational diabetes mellitus in Chinese pregnant women. | Wang X et al. | — | 2017 | → |
| Levels of heavy metals and their binding protein metallothionein in type 2 diabetics with kidney disease. | Raudenska M et al. | — | 2017 | → |
| Long Noncoding RNAs as Diagnostic and Therapeutic Targets in Type 2 Diabetes and Related Complications. | Leti F et al. | — | 2017 | → |
| Maternal serum ADAMTS-9 levels in gestational diabetes: a pilot study. | Artunc-Ulkumen B et al. | — | 2017 | → |
| Microbial Regulation of Glucose Metabolism and Insulin Resistance. | Crommen S et al. | — | 2017 | → |
| Mining the Genome for Therapeutic Targets. | Florez JC | — | 2017 | → |
| Obstacles to Translating Genotype-Phenotype Correlates in Metabolic Disease. | Sharma A et al. | — | 2017 | → |
| Pancreatic alpha cell-selective deletion of Tcf7l2 impairs glucagon secretion and counter-regulatory responses to hypoglycaemia in mice. | da Silva Xavier G et al. | — | 2017 | → |
| Penetrance of Polygenic Obesity Susceptibility Loci across the Body Mass Index Distribution. | Abadi A et al. | — | 2017 | → |
| Persistent organic pollutants and risk of diabetes and obesity on healthy adults: Results from a cross-sectional study in Spain. | Henríquez-Hernández LA et al. | — | 2017 | → |
| Physiological roles of zinc transporters: molecular and genetic importance in zinc homeostasis. | Hara T et al. | — | 2017 | → |
| Predicting phenotypes from microarrays using amplified, initially marginal, eigenvector regression. | Ding L et al. | — | 2017 | → |
| Prediction of gene expression with cis-SNPs using mixed models and regularization methods. | Zeng P et al. | — | 2017 | → |
| Presence of diabetes autoantigens in extracellular vesicles derived from human islets. | Hasilo CP et al. | — | 2017 | → |
| Prioritising Causal Genes at Type 2 Diabetes Risk Loci. | Grotz AK et al. | — | 2017 | → |
| Prokaryotic expression and characterization of the heterodimeric construction of ZnT8 and its application for autoantibodies detection in diabetes mellitus. | Faccinetti NI et al. | — | 2017 | → |
| Risk factors for neuropathic pain in diabetes mellitus. | Hébert HL et al. | — | 2017 | → |
| Sequence robust association test for familial data. | Dai W et al. | — | 2017 | → |
| SLC30A9 mutation affecting intracellular zinc homeostasis causes a novel cerebro-renal syndrome. | Perez Y et al. | — | 2017 | → |
| Stigmasterol prevents glucolipotoxicity induced defects in glucose-stimulated insulin secretion. | Ward MG et al. | — | 2017 | → |
| Study of IL4-590C/T and IL6-174G/C Gene Polymorphisms in Type 2 Diabetic Patients With Chronic Kidney Disease in North Indian Population. | Neelofar K et al. | — | 2017 | → |
| The Combined Effects of Genetic Variation in the CNDP1 and CNDP2 Genes and Dietary Carbohydrate and Carotene Intake on Obesity Risk. | Yamakawa-Kobayashi K et al. | — | 2017 | → |
| The dynamic plasticity of insulin production in β-cells. | Boland BB et al. | — | 2017 | → |
| The Nuclear Receptor HIZR-1 Uses Zinc as a Ligand to Mediate Homeostasis in Response to High Zinc. | Warnhoff K et al. | — | 2017 | → |
| The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus. | Gerber PA et al. | — | 2017 | → |
| The rs7903146 Variant in the <i>TCF7L2</i> Gene Increases the Risk of Prediabetes/Type 2 Diabetes in Obese Adolescents by Impairing β-Cell Function and Hepatic Insulin Sensitivity. | Cropano C et al. | — | 2017 | → |
| Tissue-specific methylation profile in obese patients with type 2 diabetes before and after Roux-en-Y gastric bypass. | Sala P et al. | — | 2017 | → |
| Trace Elements and Healthcare: A Bioinformatics Perspective. | Zhang Y | — | 2017 | → |
| Type 2 Diabetes Susceptibility in the Greek-Cypriot Population: Replication of Associations with TCF7L2, FTO, HHEX, SLC30A8 and IGF2BP2 Polymorphisms. | Votsi C et al. | — | 2017 | → |
| Understanding the Contribution of Zinc Transporters in the Function of the Early Secretory Pathway. | Kambe T et al. | — | 2017 | → |
| Utilization of genetic data can improve the prediction of type 2 diabetes incidence in a Swedish cohort. | Zarkoob H et al. | — | 2017 | → |
| Whole-genome resequencing of 292 pigeonpea accessions identifies genomic regions associated with domestication and agronomic traits. | Varshney RK et al. | — | 2017 | → |
| Zinc as a Gatekeeper of Immune Function. | Wessels I et al. | — | 2017 | → |
| Zinc regulates Nox1 expression through a NF-κB and mitochondrial ROS dependent mechanism to induce senescence of vascular smooth muscle cells. | Salazar G et al. | — | 2017 | → |
| Zinc transporters and insulin resistance: therapeutic implications for type 2 diabetes and metabolic disease. | Norouzi S et al. | — | 2017 | → |
| A common variant within the HNF1B gene is associated with overall survival of multiple myeloma patients: results from the IMMEnSE consortium and meta-analysis. | Ríos-Tamayo R et al. | — | 2016 | → |
| Age-related macular degeneration: genome-wide association studies to translation. | Black JR et al. | — | 2016 | → |
| A meta-analytic framework for detection of genetic interactions. | Liu Y et al. | — | 2016 | → |
| Analysis of multiple related phenotypes in genome-wide association studies. | Oh S et al. | — | 2016 | → |
| Analysis of Zinc-Exporters Expression in Prostate Cancer. | Singh CK et al. | — | 2016 | → |
| A new model calling procedure for Illumina BeadArray data. | Li G | — | 2016 | → |
| Animal models for diabetes: Understanding the pathogenesis and finding new treatments. | King A et al. | — | 2016 | → |
| A portable optical waveguide resonance light-scattering scanner for microarray detection. | Xing X et al. | — | 2016 | → |
| Assignment of Functional Relevance to Genes at Type 2 Diabetes-Associated Loci Through Investigation of β-Cell Mass Deficits. | O'Hare EA et al. | — | 2016 | → |
| Association between IGF2BP2 Polymorphisms and Type 2 Diabetes Mellitus: A Case-Control Study and Meta-Analysis. | Rao P et al. | — | 2016 | → |
| Association between the rs7903146 Polymorphism in the TCF7L2 Gene and Parameters Derived with Continuous Glucose Monitoring in Individuals without Diabetes. | van der Kroef S et al. | — | 2016 | → |
| Association of CDKAL1, CDKN2A/B & HHEX gene polymorphisms with type 2 diabetes mellitus in the population of Hyderabad, India. | Kommoju UJ et al. | — | 2016 | → |
| Association of SLC30A8 gene polymorphism with type 2 diabetes, evidence from 46 studies: a meta-analysis. | Fan M et al. | — | 2016 | → |
| Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice. | Mehta ZB et al. | — | 2016 | → |
| Characterization of zinc transporter 8 (ZnT8) antibodies in autoimmune diabetic patients from Argentinian population using monomeric, homodimeric, and heterodimeric ZnT8 antigen variants. | Faccinetti NI et al. | — | 2016 | → |
| Cholesteryl Ester Transfer Protein (CETP) expression does not affect glucose homeostasis and insulin secretion: studies in human CETP transgenic mice. | Raposo HF et al. | — | 2016 | → |
| Clinical and molecular characterization of a novel INS mutation identified in patients with MODY phenotype. | Piccini B et al. | — | 2016 | → |
| Confirming an integrated pathology of diabetes and its complications by molecular biomarker-target network analysis. | Zhao Z et al. | — | 2016 | → |
| Crystal Structure and Function of PqqF Protein in the Pyrroloquinoline Quinone Biosynthetic Pathway. | Wei Q et al. | — | 2016 | → |
| Different role of zinc transporter 8 between type 1 diabetes mellitus and type 2 diabetes mellitus. | Yi B et al. | — | 2016 | → |
| Does Zinc Really "Metal" with Diabetes? The Epidemiologic Evidence. | Ruz M et al. | — | 2016 | → |
| Effect of Socioeconomic Factors and Family History on the Incidence of Diabetes in an Adult Diabetic Population from Algeria. | Ferdi NE et al. | — | 2016 | → |
| Effect of the Interplay Between Genetic and Behavioral Risks on Survival After Age 75. | Rizzuto D et al. | — | 2016 | → |
| Evaluation of common variants in <i>MG53</i> and the risk of type 2 diabetes and insulin resistance in Han Chinese. | Yang S et al. | — | 2016 | → |
| Gene Polymorphism Association with Type 2 Diabetes and Related Gene-Gene and Gene-Environment Interactions in a Uyghur Population. | Xiao S et al. | — | 2016 | → |
| Genes associated with diabetes: potential for novel therapeutic targets? | Hara K et al. | — | 2016 | → |
| Genetic architecture of nonadditive inheritance in Arabidopsis thaliana hybrids. | Seymour DK et al. | — | 2016 | → |
| Genetic Component of Type 2 Diabetes in a Mexican Population. | Sánchez-Pozos K et al. | — | 2016 | → |
| Genetic markers of type 2 diabetes: Progress in genome-wide association studies and clinical application for risk prediction. | Wang X et al. | — | 2016 | → |
| Genetic Studies on Polycystic Ovary Syndrome. | Zhao H et al. | — | 2016 | → |
| Genetic susceptibility for insulin resistance among Egyptian women. | Zaki ME et al. | — | 2016 | → |
| Genetic variants associated with lean and obese type 2 diabetes in a Han Chinese population: A case-control study. | Kong X et al. | — | 2016 | → |
| Genetic variations in TCF7L2 influence therapeutic response to sulfonylureas in Indian diabetics. | Dhawan D et al. | — | 2016 | → |
| Glaucoma Genetics: Recent Advances and Future Directions. | Aung T et al. | — | 2016 | → |
| Hepatic ZIP14-mediated Zinc Transport Contributes to Endosomal Insulin Receptor Trafficking and Glucose Metabolism. | Aydemir TB et al. | — | 2016 | → |
| High-fat-diet induced development of increased fasting glucose levels and impaired response to intraperitoneal glucose challenge in the collaborative cross mouse genetic reference population. | Atamni HJ et al. | — | 2016 | → |
| Identification of matrix metalloproteinase-12 as a candidate molecule for prevention and treatment of cardiometabolic disease. | Amor M et al. | — | 2016 | → |
| If genetic variation could talk: What genomic data may teach us about the importance of gene expression regulation in the genetics of autism. | Yeh E et al. | — | 2016 | → |
| Impact of diabetes-related gene polymorphisms on the clinical characteristics of type 2 diabetes Chinese Han population. | Li J et al. | — | 2016 | → |
| Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium. | Palmer ND et al. | — | 2016 | → |
| Insulin Clearance Is Associated with Hepatic Lipase Activity and Lipid and Adiposity Traits in Mexican Americans. | Labadzhyan A et al. | — | 2016 | → |
| Insulin-degrading enzyme: new therapeutic target for diabetes and Alzheimer's disease? | Pivovarova O et al. | — | 2016 | → |
| Integrator of Stress Responses Calmodulin Binding Transcription Activator 1 (Camta1) Regulates miR-212/miR-132 Expression and Insulin Secretion. | Mollet IG et al. | — | 2016 | → |
| Intracellular zinc in insulin secretion and action: a determinant of diabetes risk? | Rutter GA et al. | — | 2016 | → |
| Lack of Association between <i>SLC30A8</i> Variants and Type 2 Diabetes in Mexican American Families. | Kulkarni H et al. | — | 2016 | → |
| Lipid-tuned Zinc Transport Activity of Human ZnT8 Protein Correlates with Risk for Type-2 Diabetes. | Merriman C et al. | — | 2016 | → |
| Metabolic pathways in the periphery and brain: Contribution to mental disorders? | Nagalski A et al. | — | 2016 | → |
| Misregulation of the proline rich homeodomain (PRH/HHEX) protein in cancer cells and its consequences for tumour growth and invasion. | Gaston K et al. | — | 2016 | → |
| Molecular Genetic Regulation of Slc30a8/ZnT8 Reveals a Positive Association With Glucose Tolerance. | Mitchell RK et al. | — | 2016 | → |
| Multiple testing correction in linear mixed models. | Joo JW et al. | — | 2016 | → |
| Next generation sequencing: implications in personalized medicine and pharmacogenomics. | Rabbani B et al. | — | 2016 | → |
| Over-expression of Slc30a8/ZnT8 selectively in the mouse α cell impairs glucagon release and responses to hypoglycemia. | Solomou A et al. | — | 2016 | → |
| Pathway and network-based strategies to translate genetic discoveries into effective therapies. | Greene CS et al. | — | 2016 | → |
| Pdcd2l Promotes Palmitate-Induced Pancreatic Beta-Cell Apoptosis as a FoxO1 Target Gene. | Yin Y et al. | — | 2016 | → |
| Peripheral Artery Disease and Aortic Disease. | Criqui MH et al. | — | 2016 | → |
| Pharmacogenomics in type 2 diabetes: oral antidiabetic drugs. | Daniels MA et al. | — | 2016 | → |
| Positive autoantibodies to ZnT8 indicate elevated risk for additional autoimmune conditions in patients with Addison's disease. | Fichna M et al. | — | 2016 | → |
| [Prevalence of diabetes mellitus and associated factors in indigenous women in Dourados, Mato Grosso do Sul State, Brazil]. | Freitas GA et al. | — | 2016 | → |
| Recent progress in genetic and epigenetic research on type 2 diabetes. | Kwak SH et al. | — | 2016 | → |
| Regulation of the assembly and amyloid aggregation of murine amylin by zinc. | Erthal LC et al. | — | 2016 | → |
| Renin-Angiotensin System Gene Variants and Type 2 Diabetes Mellitus: Influence of Angiotensinogen. | Joyce-Tan SM et al. | — | 2016 | → |
| Replication and Relevance of Multiple Susceptibility Loci Discovered from Genome Wide Association Studies for Type 2 Diabetes in an Indian Population. | Phani NM et al. | — | 2016 | → |
| Replication Study in a Japanese Population of Six Susceptibility Loci for Type 2 Diabetes Originally Identified by a Transethnic Meta-Analysis of Genome-Wide Association Studies. | Matsuba R et al. | — | 2016 | → |
| Roles of Zinc Signaling in the Immune System. | Hojyo S et al. | — | 2016 | → |
| Serum gamma-glutamyl transferase and risk of type 2 diabetes in the general Korean population: a Mendelian randomization study. | Lee YS et al. | — | 2016 | → |
| Single-Cell Mass Cytometry Analysis of the Human Endocrine Pancreas. | Wang YJ et al. | — | 2016 | → |
| Targeting Insulin-Degrading Enzyme to Treat Type 2 Diabetes Mellitus. | Tang WJ | — | 2016 | → |
| TarNet: An Evidence-Based Database for Natural Medicine Research. | Hu R et al. | — | 2016 | → |
| The effects of body mass index on the hereditary influences that determine peak bone mass in mother-daughter pairs (KNHANES V). | Kim KM et al. | — | 2016 | → |
| The Functions of Metallothionein and ZIP and ZnT Transporters: An Overview and Perspective. | Kimura T et al. | — | 2016 | → |
| The prevalence and predictive value of the SLC30A8 R325W polymorphism and zinc transporter 8 autoantibodies in the development of GDM and postpartum type 1 diabetes. | Dereke J et al. | — | 2016 | → |
| The therapeutic potential of metabolic hormones in the treatment of age-related cognitive decline and Alzheimer's disease. | Grizzanti J et al. | — | 2016 | → |
| The zinc transporter ZNT3 co-localizes with insulin in INS-1E pancreatic beta cells and influences cell survival, insulin secretion capacity, and ZNT8 expression. | Smidt K et al. | — | 2016 | → |
| Transgenerational effects of parental cardiovascular disease and risk factors on offspring mortality: family-linkage data from the HUNT Study, Norway. | Vik KL et al. | — | 2016 | → |
| Triphenylamine-based Schiff bases as the High sensitive Al(3+) or Zn(2+) fluorescence turn-on probe: Mechanism and application in vitro and in vivo. | Li W et al. | — | 2016 | → |
| Two variants on T2DM susceptible gene HHEX are associated with CRC risk in a Chinese population. | Sun R et al. | — | 2016 | → |
| Type 2 diabetes: genetic data sharing to advance complex disease research. | Flannick J et al. | — | 2016 | → |
| Understanding Genetic Heterogeneity in Type 2 Diabetes by Delineating Physiological Phenotypes: SIRT1 and its Gene Network in Impaired Insulin Secretion. | Ali S et al. | — | 2016 | → |
| Validation of Type 2 Diabetes Risk Variants Identified by Genome-Wide Association Studies in Northern Han Chinese. | Rao P et al. | — | 2016 | → |
| Whole-genome re-sequencing for the identification of high contribution susceptibility gene variants in patients with type 2 diabetes. | Sun X et al. | — | 2016 | → |
| Zinc and diabetes. | Chabosseau P et al. | — | 2016 | → |
| Zinc-Associated Variant in SLC30A8 Gene Interacts With Gestational Weight Gain on Postpartum Glycemic Changes: A Longitudinal Study in Women With Prior Gestational Diabetes Mellitus. | Wang T et al. | — | 2016 | → |
| Zinc transporters and signaling in physiology and pathogenesis. | Hojyo S et al. | — | 2016 | → |
| Zinc Transport Gets Its Zing Back: Double-Knockout of ZnT7 and ZnT8 Reveals the Importance of Zinc Transporters to Insulin Secretion. | Nunemaker CS et al. | — | 2016 | → |
| Activation of innate immunity modulates insulin sensitivity, glucose effectiveness and pancreatic β-cell function in both African ancestry and European ancestry healthy humans. | Ferguson JF et al. | — | 2015 | → |
| A modular system of DNA enhancer elements mediates tissue-specific activation of transcription by high dietary zinc in C. elegans. | Roh HC et al. | — | 2015 | → |
| An epidemiological perspective of personalized medicine: the Estonian experience. | Milani L et al. | — | 2015 | → |
| An explained variance-based genetic risk score associated with gestational diabetes antecedent and with progression to pre-diabetes and type 2 diabetes: a cohort study. | Cormier H et al. | — | 2015 | → |
| A robust distribution-free test for genetic association studies of quantitative traits. | Kozlitina J et al. | — | 2015 | → |
| Association between SLC30A8 rs13266634 Polymorphism and Type 2 Diabetes Risk: A Meta-Analysis. | Cheng L et al. | — | 2015 | → |
| Association between the TCF7L2 rs12255372 (G/T) gene polymorphism and type 2 diabetes mellitus in a Cameroonian population: a pilot study. | Nanfa D et al. | — | 2015 | → |
| Association between transcription factor 7-like 2 rs7903146 polymorphism and diabetic retinopathy in type 2 diabetes mellitus: A meta-analysis. | Ding Y et al. | — | 2015 | → |
| Association of a genetic variant of the ZPR1 zinc finger gene with type 2 diabetes mellitus. | Tokoro F et al. | — | 2015 | → |
| Association of genetic variants of the α-kinase 1 gene with type 2 diabetes mellitus in a longitudinal population-based genetic epidemiological study. | Yamada Y et al. | — | 2015 | → |
| Association of gene variants with susceptibility to type 2 diabetes among Omanis. | Al-Sinani S et al. | — | 2015 | → |
| Association of the Genetic Polymorphisms in Transcription Factor 7-Like 2 and Peroxisome Proliferator-Activated Receptors- γ 2 with Type 2 Diabetes Mellitus and is Interaction with Obesity Status in Emirati Population. | Al-Safar H et al. | — | 2015 | → |
| Association of Type 2 Diabetes Mellitus related SNP genotypes with altered serum adipokine levels and metabolic syndrome phenotypes. | Al-Daghri NM et al. | — | 2015 | → |
| Association study of polymorphisms in miRNAs with T2DM in Chinese population. | Li Y et al. | — | 2015 | → |
| ATP-dependent potassium channels and type 2 diabetes mellitus. | Bonfanti DH et al. | — | 2015 | → |
| Beta Cell Function and the Nutritional State: Dietary Factors that Influence Insulin Secretion. | Moore WT et al. | — | 2015 | → |
| Beyond the Protein-Coding Sequence: Noncoding RNAs in the Pathogenesis of Type 2 Diabetes. | DiStefano JK | — | 2015 | → |
| Bridging-type enzyme-linked immunoassay for zinc transporter 8 autoantibody measurements in adult patients with diabetes mellitus. | Dunseath G et al. | — | 2015 | → |
| Calcium release channel RyR2 regulates insulin release and glucose homeostasis. | Santulli G et al. | — | 2015 | → |
| Can data science inform environmental justice and community risk screening for type 2 diabetes? | Davis JA et al. | — | 2015 | → |
| Cation Diffusion Facilitator family: Structure and function. | Kolaj-Robin O et al. | — | 2015 | → |
| CDKN2A-rs10811661 polymorphism, waist-hip ratio, systolic blood pressure, and dyslipidemia are the independent risk factors for prediabetes in a Vietnamese population. | Binh TQ et al. | — | 2015 | → |
| Changes in Zinc Transporter 8 Autoantibodies Following Type 1 Diabetes Onset: The Type 1 Diabetes Genetics Consortium Autoantibody Workshop. | Wenzlau JM et al. | — | 2015 | → |
| Characterization of the transcriptional machinery bound across the widely presumed type 2 diabetes causal variant, rs7903146, within TCF7L2. | Xia Q et al. | — | 2015 | → |
| Complex Genetics of Type 2 Diabetes and Effect Size: What have We Learned from Isolated Populations? | Nair AK et al. | — | 2015 | → |
| Contribution of ENPP1, TCF7L2, and FTO polymorphisms to type 2 diabetes in mixed ancestry ethnic population of South Africa. | Yako YY et al. | — | 2015 | → |
| Contribution of the TCF7L2 rs7903146 (C/T) gene polymorphism to the susceptibility to type 2 diabetes mellitus in Cameroon. | Guewo-Fokeng M et al. | — | 2015 | → |
| Correlation between <i>KCNQ1</i> and <i>KCNJ11</i> gene polymorphisms and type 2 and post-transplant diabetes mellitus in the Asian Indian population. | Khan IA et al. | — | 2015 | → |
| Cumulative effect and predictive value of genetic variants associated with type 2 diabetes in Han Chinese: a case-control study. | Qian Y et al. | — | 2015 | → |
| Current and Future Clinical Applications of Zinc Transporter-8 in Type 1 Diabetes Mellitus. | Yi B et al. | — | 2015 | → |
| Design of an allele-specific PCR assay to genotype the rs12255372 SNP in a pilot study of association between common TCF7L2 polymorphisms and type 2 diabetes in Venezuelans. | Moran Y et al. | — | 2015 | → |
| Deterministic identification of specific individuals from GWAS results. | Cai R et al. | — | 2015 | → |
| Dietary fat and carbohydrate modulate the effect of the ATP-binding cassette A1 (ABCA1) R230C variant on metabolic risk parameters in premenopausal women from the Genetics of Atherosclerotic Disease (GEA) Study. | Jacobo-Albavera L et al. | — | 2015 | → |
| Differential Natural Selection of Human Zinc Transporter Genes between African and Non-African Populations. | Zhang C et al. | — | 2015 | → |
| Docosahexaenoic Acid-Rich Fish Oil Supplementation Improves Body Composition without Influence of the PPARγ Pro12Ala Polymorphism in Patients with Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. | Mansoori A et al. | — | 2015 | → |
| Do variants associated with susceptibility to pancreatic cancer and type 2 diabetes reciprocally affect risk? | Wu L et al. | — | 2015 | → |
| Ecological correlation between diabetes hospitalizations and fine particulate matter in Italian provinces. | Solimini AG et al. | — | 2015 | → |
| EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals. | Gore AC et al. | — | 2015 | → |
| Effect of zinc supplementation on insulin secretion: interaction between zinc and SLC30A8 genotype in Old Order Amish. | Maruthur NM et al. | — | 2015 | → |
| Elite athletes' genetic predisposition for altered risk of complex metabolic traits. | Banting LK et al. | — | 2015 | → |
| Evaluation of a two-step iterative resampling procedure for internal validation of genome-wide association studies. | Kang G et al. | — | 2015 | → |
| Evidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in mice. | Bailey KA et al. | — | 2015 | → |
| Fine mapping and whole-exome sequencing of a familial cortical myoclonic tremor with epilepsy family. | Cen ZD et al. | — | 2015 | → |
| Fine-scale human genetic structure in Western France. | Karakachoff M et al. | — | 2015 | → |
| Gene Expression Signature in Adipose Tissue of Acromegaly Patients. | Hochberg I et al. | — | 2015 | → |
| Genetic architecture of insulin resistance in the mouse. | Parks BW et al. | — | 2015 | → |
| Genetic Determinants of Type 2 Diabetes in Asians. | Qi Q et al. | — | 2015 | → |
| Genetic differentiation of brackish water populations of cod Gadus morhua in the southern Baltic, inferred from genotyping using SNP-arrays. | Poćwierz-Kotus A et al. | — | 2015 | → |
| Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. | Gaulton KJ et al. | — | 2015 | → |
| Genetics, genomics and personalized medicine in Type 2 diabetes: a perspective on the Arab region. | Siddiqui K et al. | — | 2015 | → |
| Genetics of Type 2 Diabetes and Clinical Utility. | Dorajoo R et al. | — | 2015 | → |
| Genetics of Type 2 Diabetes in African Americans. | Ng MC | — | 2015 | → |
| Genetics of type 2 diabetes-pitfalls and possibilities. | Prasad RB et al. | — | 2015 | → |
| Genetic Studies on Diabetic Microvascular Complications: Focusing on Genome-Wide Association Studies. | Kwak SH et al. | — | 2015 | → |
| Genetic underpinnings of left superior temporal gyrus thickness in patients with schizophrenia. | Wolthusen RP et al. | — | 2015 | → |
| Genetic variants associated with motion sickness point to roles for inner ear development, neurological processes and glucose homeostasis. | Hromatka BS et al. | — | 2015 | → |
| Genetic variation at glucose and insulin trait loci and response to glucose-insulin-potassium (GIK) therapy: the IMMEDIATE trial. | Ellis KL et al. | — | 2015 | → |
| Genome-wide association study reveals a set of genes associated with resistance to the Mediterranean corn borer (Sesamia nonagrioides L.) in a maize diversity panel. | Samayoa LF et al. | — | 2015 | → |
| Habitual coffee intake, genetic polymorphisms, and type 2 diabetes. | Lee JK et al. | — | 2015 | → |
| Hepatocyte nuclear factor 4 alpha polymorphisms and the metabolic syndrome in French-Canadian youth. | Marcil V et al. | — | 2015 | → |
| HHEX_23 AA Genotype Exacerbates Effect of Diabetes on Dementia and Alzheimer Disease: A Population-Based Longitudinal Study. | Xu WL et al. | — | 2015 | → |
| How our bodies fight amyloidosis: effects of physiological factors on pathogenic aggregation of amyloidogenic proteins. | Huang L et al. | — | 2015 | → |
| Identification of novel genes for glucose metabolism based upon expression pattern in human islets and effect on insulin secretion and glycemia. | Taneera J et al. | — | 2015 | → |
| Impact of variants of the EXT2 gene on Type 2 diabetes and its related traits in the Chinese han population. | Ren Q et al. | — | 2015 | → |
| Increased DNA methylation of the SLC30A8 gene promoter is associated with type 2 diabetes in a Malay population. | Seman NA et al. | — | 2015 | → |
| Influence of Feature Encoding and Choice of Classifier on Disease Risk Prediction in Genome-Wide Association Studies. | Mittag F et al. | — | 2015 | → |
| Inhibition of IAPP aggregation by insulin depends on the insulin oligomeric state regulated by zinc ion concentration. | Nedumpully-Govindan P et al. | — | 2015 | → |
| Integrated genomic and BMI analysis for type 2 diabetes risk assessment. | Lebrón-Aldea D et al. | — | 2015 | → |
| Interaction of Wnt pathway related variants with type 2 diabetes in a Chinese Han population. | Zhou JB et al. | — | 2015 | → |
| Krüppel-like factor 14 increases insulin sensitivity through activation of PI3K/Akt signal pathway. | Yang M et al. | — | 2015 | → |
| Latent autoimmune diabetes of the adult: current knowledge and uncertainty. | Laugesen E et al. | — | 2015 | → |
| Liver-specific expression of dominant-negative transcription factor 7-like 2 causes progressive impairment in glucose homeostasis. | Ip W et al. | — | 2015 | → |
| Low-Density Lipoprotein Receptor-Related Protein 6 (LRP6) Is a Novel Nutritional Therapeutic Target for Hyperlipidemia, Non-Alcoholic Fatty Liver Disease, and Atherosclerosis. | Go GW | — | 2015 | → |
| Low-frequency germline variants across 6p22.2-6p21.33 are associated with non-obstructive azoospermia in Han Chinese men. | Ni B et al. | — | 2015 | → |
| M(3)-S: a genotype calling method incorporating information from samples with known genotypes. | Li G et al. | — | 2015 | → |
| Mechanistic Contributions of Biological Cofactors in Islet Amyloid Polypeptide Amyloidogenesis. | Nguyen PT et al. | — | 2015 | → |
| Methods for biological data integration: perspectives and challenges. | Gligorijević V et al. | — | 2015 | → |
| Modelling the Interplay between Lifestyle Factors and Genetic Predisposition on Markers of Type 2 Diabetes Mellitus Risk. | Walker CG et al. | — | 2015 | → |
| New insights from monogenic diabetes for "common" type 2 diabetes. | Tallapragada DS et al. | — | 2015 | → |
| Obesity and Pro12Ala Polymorphism of Peroxisome Proliferator-Activated Receptor-Gamma Gene in Healthy Adults: A Systematic Review and Meta-Analysis. | Mansoori A et al. | — | 2015 | → |
| Pharmacogenomics of glinides. | Chen M et al. | — | 2015 | → |
| Polymorphism in the transcription factor 7-like 2 (TCF7L2) gene is associated with impaired proinsulin conversion--A meta-analysis. | Shen J et al. | — | 2015 | → |
| Polymorphism of Transcription Factor-7-Like 2 (TCF7L2) Gene and New-Onset Diabetes after Liver Transplantation. | Musavi Z et al. | — | 2015 | → |
| Quality control metrics improve repeatability and reproducibility of single-nucleotide variants derived from whole-genome sequencing. | Zhang W et al. | — | 2015 | → |
| Rare and common genetic events in type 2 diabetes: what should biologists know? | Bonnefond A et al. | — | 2015 | → |
| Replication of KCNJ11 (p.E23K) and ABCC8 (p.S1369A) Association in Russian Diabetes Mellitus 2 Type Cohort and Meta-Analysis. | Sokolova EA et al. | — | 2015 | → |
| Replication Study in a Japanese Population to Evaluate the Association between 10 SNP Loci, Identified in European Genome-Wide Association Studies, and Type 2 Diabetes. | Matsuba R et al. | — | 2015 | → |
| Review and evaluation of electronic health records-driven phenotype algorithm authoring tools for clinical and translational research. | Xu J et al. | — | 2015 | → |
| Robust Association Tests for the Replication of Genome-Wide Association Studies. | Joo J et al. | — | 2015 | → |
| Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass. | Mitchell RK et al. | — | 2015 | → |
| Should we have blind faith in bioinformatics software? Illustrations from the SNAP web-based tool. | Robiou-du-Pont S et al. | — | 2015 | → |
| SLC30A8 mutations in type 2 diabetes. | Rutter GA et al. | — | 2015 | → |
| SLC transporters as therapeutic targets: emerging opportunities. | Lin L et al. | — | 2015 | → |
| Statistical analysis for genome-wide association study. | Zeng P et al. | — | 2015 | → |
| Stratified medicine for the use of antidiabetic medication in treatment of type II diabetes and cancer: where do we go from here? | Emami-Riedmaier A et al. | — | 2015 | → |
| Structural Properties of Gene Promoters Highlight More than Two Phenotypes of Diabetes. | Ionescu-Tîrgovişte C et al. | — | 2015 | → |
| SVSI: fast and powerful set-valued system identification approach to identifying rare variants in sequencing studies for ordered categorical traits. | Bi W et al. | — | 2015 | → |
| The Association of Type 2 Diabetes Loci Identified in Genome-Wide Association Studies with Metabolic Syndrome and Its Components in a Chinese Population with Type 2 Diabetes. | Kong X et al. | — | 2015 | → |
| The expression of dominant negative TCF7L2 in pancreatic beta cells during the embryonic stage causes impaired glucose homeostasis. | Shao W et al. | — | 2015 | → |
| The genetics of diabetic pregnancy. | Bajaj K et al. | — | 2015 | → |
| The Physiological, Biochemical, and Molecular Roles of Zinc Transporters in Zinc Homeostasis and Metabolism. | Kambe T et al. | — | 2015 | → |
| The physiological role of drug transporters. | Liang Y et al. | — | 2015 | → |
| The type 2 diabetes associated rs7903146 T allele within TCF7L2 is significantly under-represented in Hereditary Multiple Exostoses: insights into pathogenesis. | Sgariglia F et al. | — | 2015 | → |
| The use of genetic information in the prediction of Type 2 diabetes. | Drenos F | — | 2015 | → |
| The Uyghur population and genetic susceptibility to type 2 diabetes: potential role for variants in CDKAL1, JAZF1, and IGF1 genes. | Song M et al. | — | 2015 | → |
| The Zinc Transporter Slc30a8/ZnT8 Is Required in a Subpopulation of Pancreatic α-Cells for Hypoglycemia-induced Glucagon Secretion. | Solomou A et al. | — | 2015 | → |
| Transcriptomic identification of ADH1B as a novel candidate gene for obesity and insulin resistance in human adipose tissue in Mexican Americans from the Veterans Administration Genetic Epidemiology Study (VAGES). | Winnier DA et al. | — | 2015 | → |
| Type 2 diabetes as a protein misfolding disease. | Mukherjee A et al. | — | 2015 | → |
| Type 2 diabetes mellitus. | DeFronzo RA et al. | — | 2015 | → |
| Type 2 Diabetes Mellitus and the Association of Candidate Genes in Asian Indian Population from Hyderabad, India. | Khan IA et al. | — | 2015 | → |
| Type 2 diabetes-related variants influence the risk of developing multiple myeloma: results from the IMMEnSE consortium. | Ríos R et al. | — | 2015 | → |
| Validation of the association of TCF7L2 and SLC30A8 gene polymorphisms with post-transplant diabetes mellitus in Asian Indian population. | Khan IA et al. | — | 2015 | → |
| Work-related psychosocial stress and glycemic control among working adults with diabetes mellitus. | Annor FB et al. | — | 2015 | → |
| Zinc transporter 8 autoantibodies: what is their clinical relevance in gestational diabetes? | Rudland VL et al. | — | 2015 | → |
| Zinc transporter 8 (ZnT8) autoantibody epitope specificity and affinity examined with recombinant ZnT8 variant proteins in specific ZnT8R and ZnT8W autoantibody-positive type 1 diabetes patients. | Skärstrand H et al. | — | 2015 | → |
| Zinc transporters and zinc signaling: new insights into their role in type 2 diabetes. | Myers SA | — | 2015 | → |
| Zip4 mediated zinc influx stimulates insulin secretion in pancreatic beta cells. | Hardy AB et al. | — | 2015 | → |
| A central role for GRB10 in regulation of islet function in man. | Prokopenko I et al. | — | 2014 | → |
| Admixture mapping and subsequent fine-mapping suggests a biologically relevant and novel association on chromosome 11 for type 2 diabetes in African Americans. | Jeff JM et al. | — | 2014 | → |
| A new association test based on disease allele selection for case-control genome-wide association studies. | Chen Z | — | 2014 | → |
| A new system identification approach to identify genetic variants in sequencing studies for a binary phenotype. | Kang G et al. | — | 2014 | → |
| A novel method, the Variant Impact On Linkage Effect Test (VIOLET), leads to improved identification of causal variants in linkage regions. | Martin LJ et al. | — | 2014 | → |
| Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones. | Maianti JP et al. | — | 2014 | → |
| Antiretroviral therapy modifies the genetic effect of known type 2 diabetes-associated risk variants in HIV-infected women. | Frasco MA et al. | — | 2014 | → |
| A robust method for genome-wide association meta-analysis with the application to circulating insulin-like growth factor I concentrations. | Wang T et al. | — | 2014 | → |
| A set-based association test identifies sex-specific gene sets associated with type 2 diabetes. | He T et al. | — | 2014 | → |
| Assessing the contribution of 38 genetic loci to the risk of type 2 diabetes in the Saudi Arabian Population. | Al-Daghri NM et al. | — | 2014 | → |
| Association between type 2 diabetes mellitus-related SNP variants and obesity traits in a Saudi population. | Al-Daghri NM et al. | — | 2014 | → |
| Association of common genetic variants with diabetes and metabolic syndrome related traits in the Arizona Insulin Resistance registry: a focus on Mexican American families in the Southwest. | DeMenna J et al. | — | 2014 | → |
| Behavioral impairments in animal models for zinc deficiency. | Hagmeyer S et al. | — | 2014 | → |
| Biologically targeted probes for Zn<sup>2+</sup>: a diversity oriented modular "click-S<sub>N</sub>Ar-click" approach†Electronic supplementary information (ESI) available: Full experimental details including characterisation of all novel compounds can be found in the ESI. See DOI: 10.1039/c4sc01249f. | Pancholi J et al. | — | 2014 | → |
| Carriers of loss-of-function mutations in EXT display impaired pancreatic beta-cell reserve due to smaller pancreas volume. | Bernelot Moens SJ et al. | — | 2014 | → |
| CDKAL1 and HHEX are associated with type 2 diabetes-related traits among Yup'ik people. | Klimentidis YC et al. | — | 2014 | → |
| Computer aided screening of secreted frizzled-related protein 4 (SFRP4): a potential control for diabetes mellitus. | Bukhari SA et al. | — | 2014 | → |
| Contribution of SLC30A8 variants to the risk of type 2 diabetes in a multi-ethnic population: a case control study. | Salem SD et al. | — | 2014 | → |
| Co-occurrence of risk alleles in or near genes modulating insulin secretion predisposes obese youth to prediabetes. | Giannini C et al. | — | 2014 | → |
| Cross-sectional and longitudinal replication analyses of genome-wide association loci of type 2 diabetes in Han Chinese. | Zhao Q et al. | — | 2014 | → |
| Cross-tissue and tissue-specific eQTLs: partitioning the heritability of a complex trait. | Torres JM et al. | — | 2014 | → |
| Current understanding of ZIP and ZnT zinc transporters in human health and diseases. | Kambe T et al. | — | 2014 | → |
| Designing algorithms for determining significance of DNA missense changes. | Gowrisankar S et al. | — | 2014 | → |
| Determination of 14 circulating microRNAs in Swedes and Iraqis with and without diabetes mellitus type 2. | Wang X et al. | — | 2014 | → |
| Developing discriminate model and comparative analysis of differentially expressed genes and pathways for bloodstream samples of diabetes mellitus type 2. | Liu C et al. | — | 2014 | → |
| Diabetes burden and prevention in Korea and the Western Pacific Region. | Cho NH | — | 2014 | → |
| Dorothy Hodgkin Lecture 2014. Understanding genes identified by genome-wide association studies for type 2 diabetes. | Rutter GA | — | 2014 | → |
| Early decrease of insulin sensitivity in offspring of individuals with type 2 diabetes. The Mexican Diabetes Prevention Study. | Pérez-Fuentes R et al. | — | 2014 | → |
| Effects of NOS1AP rs12742393 polymorphism on repaglinide response in Chinese patients with type 2 diabetes mellitus. | Wang T et al. | — | 2014 | → |
| Effects of zinc supplementation and zinc chelation on in vitro β-cell function in INS-1E cells. | Nygaard SB et al. | — | 2014 | → |
| Evaluation of common type 2 diabetes risk variants in a South Asian population of Sri Lankan descent. | Hassanali N et al. | — | 2014 | → |
| Exploring genetic variants predisposing to diabetes mellitus and their association with indicators of socioeconomic status. | Schmidt B et al. | — | 2014 | → |
| Exposure to organochlorine pollutants and type 2 diabetes: a systematic review and meta-analysis. | Tang M et al. | — | 2014 | → |
| Extreme population differences in the human zinc transporter ZIP4 (SLC39A4) are explained by positive selection in Sub-Saharan Africa. | Engelken J et al. | — | 2014 | → |
| Gene dose effect between a fat mass and obesity-associated polymorphism and body mass index was observed in Korean women with polycystic ovary syndrome but not in control women. | Kim JJ et al. | — | 2014 | → |
| Genetic architecture of type 2 diabetes. | Hara K et al. | — | 2014 | → |
| Genetic basis of metabolome variation in yeast. | Breunig JS et al. | — | 2014 | → |
| Genetic differentiation of southeast Baltic populations of sea trout inferred from single nucleotide polymorphisms. | Poćwierz-Kotus A et al. | — | 2014 | → |
| Genetics of alcohol dependence: a review of clinical studies. | Samochowiec J et al. | — | 2014 | → |
| Genetics of diabetes--are we missing the genes or the disease? | Groop L et al. | — | 2014 | → |
| Genetics of type 2 diabetes: insights into the pathogenesis and its clinical application. | Sun X et al. | — | 2014 | → |
| Genetic susceptibility to type 2 diabetes and obesity: follow-up of findings from genome-wide association studies. | Basile KJ et al. | — | 2014 | → |
| Genetic Testing and Type 2 Diabetes Risk Awareness. | de Groot M et al. | — | 2014 | → |
| Genetic variant of the renin-angiotensin system and prevalence of type 2 diabetes mellitus: a modest but significant effect of aldosterone synthase. | Ichikawa M et al. | — | 2014 | → |
| Genetic variants associated with motion sickness point to roles for inner ear development, neurological processes, and glucose homeostasis | Hromatka BS et al. | — | 2014 | — |
| Genetic variants at 10q23.33 are associated with plasma lipid levels in a Chinese population. | Liu S et al. | — | 2014 | → |
| Genetic variants for type 2 diabetes and new-onset cancer in Chinese with type 2 diabetes. | Ma RC et al. | — | 2014 | → |
| Genetic Variations in the Kir6.2 Subunit (KCNJ11) of Pancreatic ATP-Sensitive Potassium Channel Gene Are Associated with Insulin Response to Glucose Loading and Early Onset of Type 2 Diabetes in Childhood and Adolescence in Taiwan. | Jiang YD et al. | — | 2014 | → |
| Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets. | Olsson AH et al. | — | 2014 | → |
| Genome-wide association study identifies three novel loci for type 2 diabetes. | Hara K et al. | — | 2014 | → |
| Genome-wide association study identifies two novel Loci with sex-specific effects for type 2 diabetes mellitus and glycemic traits in a korean population. | Go MJ et al. | — | 2014 | → |
| High cardiorespiratory fitness can reduce glycated hemoglobin levels regardless of polygenic risk for Type 2 diabetes mellitus in nondiabetic Japanese men. | Tanisawa K et al. | — | 2014 | → |
| High glucose level promotes migration behavior of breast cancer cells through zinc and its transporters. | Takatani-Nakase T et al. | — | 2014 | → |
| Human genetics of diabetic retinopathy. | Tang ZH et al. | — | 2014 | → |
| Hypoxia lowers SLC30A8/ZnT8 expression and free cytosolic Zn2+ in pancreatic beta cells. | Gerber PA et al. | — | 2014 | → |
| Identifying causal variants at loci with multiple signals of association. | Hormozdiari F et al. | — | 2014 | → |
| Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-β hydrolysis. | Charton J et al. | — | 2014 | → |
| Implications of genome-wide association studies in novel therapeutics in primary biliary cirrhosis. | Carbone M et al. | — | 2014 | → |
| Individualized medicine from prewomb to tomb. | Topol EJ | — | 2014 | → |
| Inhibition of secreted frizzled-related protein 5 improves glucose metabolism. | Rulifson IC et al. | — | 2014 | → |
| Insights into the genetic susceptibility to type 2 diabetes from genome-wide association studies of glycaemic traits. | Marullo L et al. | — | 2014 | → |
| In situ dimerization of multiple wild type and mutant zinc transporters in live cells using bimolecular fluorescence complementation. | Lasry I et al. | — | 2014 | → |
| Insulin-degrading enzyme inhibition, a novel therapy for type 2 diabetes? | Costes S et al. | — | 2014 | → |
| Interactions between zinc transporter-8 gene (SLC30A8) and plasma zinc concentrations for impaired glucose regulation and type 2 diabetes. | Shan Z et al. | — | 2014 | → |
| Joint effects of known type 2 diabetes susceptibility loci in genome-wide association study of Singapore Chinese: the Singapore Chinese health study. | Chen Z et al. | — | 2014 | → |
| Legal aspects of biobanking as key issues for personalized medicine and translational exploitation. | Minssen T et al. | — | 2014 | → |
| Lessons from Genome-Wide Search for Disease-Related Genes with Special Reference to HLA-Disease Associations. | Tokunaga K | — | 2014 | → |
| Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms. | Claussnitzer M et al. | — | 2014 | → |
| Loss-of-function mutations in SLC30A8 protect against type 2 diabetes. | Flannick J et al. | — | 2014 | → |
| Metabolic health is a more important determinant for diabetes development than simple obesity: a 4-year retrospective longitudinal study. | Rhee EJ et al. | — | 2014 | → |
| Micronutrient-gene interactions related to inflammatory/immune response and antioxidant activity in ageing and inflammation. A systematic review. | Mocchegiani E et al. | — | 2014 | → |
| Mitochondrial DNA haplogroups and risk of new-onset diabetes among tacrolimus-treated renal transplanted patients. | Tavira B et al. | — | 2014 | → |
| Moving into a new era of periodontal genetic studies: relevance of large case-control samples using severe phenotypes for genome-wide association studies. | Vaithilingam RD et al. | — | 2014 | → |
| Nutrigenetics and nutrigenomics insights into diabetes etiopathogenesis. | Berná G et al. | — | 2014 | → |
| Nutrigenetics: bridging two worlds to understand type 2 diabetes. | Harrington JM et al. | — | 2014 | → |
| Nutrigenomics: the role of nutrients in gene expression. | Dang TS et al. | — | 2014 | → |
| Overlap of genetic susceptibility to type 1 diabetes, type 2 diabetes, and latent autoimmune diabetes in adults. | Basile KJ et al. | — | 2014 | → |
| Paternally induced transgenerational inheritance of susceptibility to diabetes in mammals. | Wei Y et al. | — | 2014 | → |
| Personal history of diabetes, genetic susceptibility to diabetes, and risk of brain glioma: a pooled analysis of observational studies. | Kitahara CM et al. | — | 2014 | → |
| Predicting cognitive ability in ageing cohorts using Type 2 diabetes genetic risk. | Luciano M et al. | — | 2014 | → |
| Recent advances in the molecular genetics of type 2 diabetes mellitus. | Brunetti A et al. | — | 2014 | → |
| Regulation of insulin degrading enzyme activity by obesity-associated factors and pioglitazone in liver of diet-induced obese mice. | Wei X et al. | — | 2014 | → |
| Risk factors contributing to type 2 diabetes and recent advances in the treatment and prevention. | Wu Y et al. | — | 2014 | → |
| Roles of lncRNAs in pancreatic beta cell identity and diabetes susceptibility. | Pullen TJ et al. | — | 2014 | → |
| Search for genetic determinants of sulfonylurea efficacy in type 2 diabetic patients from China. | Ren Q et al. | — | 2014 | → |
| Simultaneous copy number losses within multiple subtelomeric regions in early-onset type 2 diabetes mellitus. | Kodama S et al. | — | 2014 | → |
| SLC30A8 nonsynonymous variant is associated with recovery following exercise and skeletal muscle size and strength. | Sprouse C et al. | — | 2014 | → |
| SNP discovery in the transcriptome of white Pacific shrimp Litopenaeus vannamei by next generation sequencing. | Yu Y et al. | — | 2014 | → |
| Statistical properties of single-marker tests for rare variants. | Bigdeli TB et al. | — | 2014 | → |
| Targeting the pancreatic β-cell to treat diabetes. | Vetere A et al. | — | 2014 | → |
| TCF7L2 is a master regulator of insulin production and processing. | Zhou Y et al. | — | 2014 | → |
| The Adiponectin variants contribute to the genetic background of type 2 diabetes in Turkish population. | Arikoglu H et al. | — | 2014 | → |
| The architecture of risk for type 2 diabetes: understanding Asia in the context of global findings. | Abdullah N et al. | — | 2014 | → |
| The families of zinc (SLC30 and SLC39) and copper (SLC31) transporters. | Schweigel-Röntgen M | — | 2014 | → |
| The integrated disease network. | Sun K et al. | — | 2014 | → |
| The role of regulatory T cell (Treg) subsets in gestational diabetes mellitus. | Schober L et al. | — | 2014 | → |
| The TCF7L2 rs7903146 polymorphism, dietary intakes and type 2 diabetes risk in an Algerian population. | Ouhaibi-Djellouli H et al. | — | 2014 | → |
| Transcription factor 7-like 2 (TCF7L2) gene polymorphism and clinical phenotype in end-stage renal disease patients. | Buraczynska M et al. | — | 2014 | → |
| Two novel type 2 diabetes loci revealed through integration of TCF7L2 DNA occupancy and SNP association data. | Johnson ME et al. | — | 2014 | → |
| Uptake epithelia behave in a cell-centric and not systems homeostatic manner in response to zinc depletion and supplementation. | Zheng D et al. | — | 2014 | → |
| Utility of large consanguineous family-based model for investigating the genetics of type 2 diabetes mellitus. | Al-Sinani S et al. | — | 2014 | → |
| Validation of type 2 diabetes risk variants identified by genome-wide association studies in Han Chinese population: a replication study and meta-analysis. | Chang YC et al. | — | 2014 | → |
| Weight loss independent association of TCF7 L2 gene polymorphism with fasting blood glucose after Roux-en-Y gastric bypass in type 2 diabetic patients. | Rouskas K et al. | — | 2014 | → |
| Zinc and its transporters, pancreatic β-cells, and insulin metabolism. | Huang L | — | 2014 | → |
| Zinc-finger BED domain-containing 3 (Zbed3) is a novel secreted protein associated with insulin resistance in humans. | Jia Y et al. | — | 2014 | → |
| Zinc proteome interaction network as a model to identify nutrient-affected pathways in human pathologies. | Leoni G et al. | — | 2014 | → |
| Zinc transport and diabetes risk. | Pearson E | — | 2014 | → |
| Zinc transporter 8 autoantibodies in patients with type 1 diabetes from a multiethnic population and their first degree relatives. | Araujo DB et al. | — | 2014 | → |
| Zinc transporter 8 (ZnT8) and β cell function. | Davidson HW et al. | — | 2014 | → |
| Zinc transporter gene expression and glycemic control in post-menopausal women with Type 2 diabetes mellitus. | Foster M et al. | — | 2014 | → |
| ACE I/D and MTHFR C677T polymorphisms are significantly associated with type 2 diabetes in Arab ethnicity: a meta-analysis. | Al-Rubeaan K et al. | — | 2013 | → |
| Achieving "PeaK-A" insulin secretion. | Evans-Molina C et al. | — | 2013 | → |
| A Drosophila functional evaluation of candidates from human genome-wide association studies of type 2 diabetes and related metabolic traits identifies tissue-specific roles for dHHEX. | Pendse J et al. | — | 2013 | → |
| A global map for dissecting phenotypic variants in human lincRNAs. | Ning S et al. | — | 2013 | → |
| A likelihood ratio test for genome-wide association under genetic heterogeneity. | Qian M et al. | — | 2013 | → |
| An f2 pig resource population as a model for genetic studies of obesity and obesity-related diseases in humans: design and genetic parameters. | Kogelman LJ et al. | — | 2013 | → |
| Animal models of GWAS-identified type 2 diabetes genes. | da Silva Xavier G et al. | — | 2013 | → |
| Antigenicity and epitope specificity of ZnT8 autoantibodies in type 1 diabetes. | Skärstrand H et al. | — | 2013 | → |
| A population-based association study of 2q32.3 and 8q21.3 loci with schizophrenia in Han Chinese. | Guan F et al. | — | 2013 | → |
| Association between donor and recipient TCF7L2 gene polymorphisms and the risk of new-onset diabetes mellitus after liver transplantation in a Han Chinese population. | Ling Q et al. | — | 2013 | → |
| Association between large detectable clonal mosaicism and type 2 diabetes with vascular complications. | Bonnefond A et al. | — | 2013 | → |
| Association between polymorphisms of the α-kinase 1 gene and type 2 diabetes mellitus in community-dwelling individuals. | Shimokata S et al. | — | 2013 | → |
| Association between variants of EXT2 and type 2 diabetes: a replication and meta-analysis. | Liu L et al. | — | 2013 | → |
| Association of adiponectin (AdipoQ) and sulphonylurea receptor (ABCC8) gene polymorphisms with Type 2 Diabetes in North Indian population of Punjab. | Matharoo K et al. | — | 2013 | → |
| Association of genetic variants with isolated fasting hyperglycaemia and isolated postprandial hyperglycaemia in a Han Chinese population. | Kong X et al. | — | 2013 | → |
| Association of risk variants for type 2 diabetes and hyperglycemia with gestational diabetes. | Huopio H et al. | — | 2013 | → |
| Association of rs12255372 in the TCF7L2 gene with type 2 diabetes mellitus: a meta-analysis. | Wang J et al. | — | 2013 | → |
| Association of rs734312 and rs10010131 polymorphisms in WFS1 gene with type 2 diabetes mellitus: a meta-analysis. | Cheng S et al. | — | 2013 | → |
| Association of TCF7L2 gene polymorphisms with T2DM in the population of Hyderabad, India. | Uma Jyothi K et al. | — | 2013 | → |
| Association of the ADRA2A polymorphisms with the risk of type 2 diabetes: a meta-analysis. | Chen X et al. | — | 2013 | → |
| Association of variants in PPARγ², IGF2BP2, and KCNQ1 with a susceptibility to gestational diabetes mellitus in a Korean population. | Chon SJ et al. | — | 2013 | → |
| Autoantibodies against zinc transporter 8 are related to age, metabolic state and HLA DR genotype in children with newly diagnosed type 1 diabetes. | Salonen KM et al. | — | 2013 | → |
| Biomarkers for early diagnosis of type 2 diabetic nephropathy: a study based on an integrated biomarker system. | Huang M et al. | — | 2013 | → |
| Bridging the gap between genetic associations and molecular mechanisms for type 2 diabetes. | Ng HJ et al. | — | 2013 | → |
| Centenarians as super-controls to assess the biological relevance of genetic risk factors for common age-related diseases: a proof of principle on type 2 diabetes. | Garagnani P et al. | — | 2013 | → |
| Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death. | Bezzina CR et al. | — | 2013 | → |
| Complex disease interventions from a network model for type 2 diabetes. | Rende D et al. | — | 2013 | → |
| Compound heterozygous mutations in SLC30A2/ZnT2 results in low milk zinc concentrations: a novel mechanism for zinc deficiency in a breast-fed infant. | Itsumura N et al. | — | 2013 | → |
| Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme. | McCord LA et al. | — | 2013 | → |
| Deep whole-genome sequencing of 100 southeast Asian Malays. | Wong LP et al. | — | 2013 | → |
| Diabetes and nonalcoholic Fatty liver disease: a pathogenic duo. | Williams KH et al. | — | 2013 | → |
| Diabetes genes identified by genome-wide association studies are regulated in mice by nutritional factors in metabolically relevant tissues and by glucose concentrations in islets. | Ho MM et al. | — | 2013 | → |
| Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease. | Bullock JM et al. | — | 2013 | → |
| Dynamic chromatin remodeling mediated by polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells. | Xie R et al. | — | 2013 | → |
| Enhancing systems medicine beyond genotype data by dynamic patient signatures: having information and using it too. | Emmert-Streib F et al. | — | 2013 | → |
| Ethical and practical challenges to studying patients who opt out of large-scale biorepository research. | Rosenbloom ST et al. | — | 2013 | → |
| Generation of high quality chromatin immunoprecipitation DNA template for high-throughput sequencing (ChIP-seq). | Deliard S et al. | — | 2013 | → |
| Genetic analysis of common variants in the CMYA5 (cardiomyopathy-associated 5) gene with schizophrenia. | Zhang R et al. | — | 2013 | → |
| Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression. | Hoffmeister A et al. | — | 2013 | → |
| Genetic association studies in female reproduction: from candidate-gene approaches to genome-wide mapping. | Zhao H et al. | — | 2013 | → |
| Genetics and genomics for the prevention and treatment of cardiovascular disease: update: a scientific statement from the American Heart Association. | Ganesh SK et al. | — | 2013 | → |
| Genetics of canine diabetes mellitus: are the diabetes susceptibility genes identified in humans involved in breed susceptibility to diabetes mellitus in dogs? | Catchpole B et al. | — | 2013 | → |
| Genetics of onset of asthma. | Dijk FN et al. | — | 2013 | → |
| Genetics of type 2 diabetes. | Ali O | — | 2013 | → |
| Genetics of type 2 diabetes and potential clinical implications. | Kwak SH et al. | — | 2013 | → |
| Genetic variations in radiation and chemotherapy drug action pathways and survival in locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapy. | Liu H et al. | — | 2013 | → |
| Genome wide association studies for diabetes: perspective on results and challenges. | Torres JM et al. | — | 2013 | → |
| Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. | Saxena R et al. | — | 2013 | → |
| Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. | Couch FJ et al. | — | 2013 | → |
| Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits. | Zheng JS et al. | — | 2013 | → |
| Human genetics of diabetic vascular complications. | Tang ZH et al. | — | 2013 | → |
| Identification of a genetic locus on chromosome 4q34-35 for type 2 diabetes with overweight. | Park MH et al. | — | 2013 | → |
| Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets. | Dayeh TA et al. | — | 2013 | → |
| Insulino-mimetic and anti-diabetic effects of zinc. | Vardatsikos G et al. | — | 2013 | → |
| IRS1, TCF7L2, ADRB1, PPARG, and HHEX polymorphisms associated with atherogenic risk in Mexican population. | Estrada-Velasco BI et al. | — | 2013 | → |
| Lack of replication of common EXT2 gene variants with susceptibility to type 2 diabetes in Lebanese Arabs. | Nemr R et al. | — | 2013 | → |
| Large-scale genotyping identifies 41 new loci associated with breast cancer risk. | Michailidou K et al. | — | 2013 | → |
| Linkage of type 2 diabetes on chromosome 9p24 in Mexican Americans: additional evidence from the Veterans Administration Genetic Epidemiology Study (VAGES). | Farook VS et al. | — | 2013 | → |
| LRP6 enhances glucose metabolism by promoting TCF7L2-dependent insulin receptor expression and IGF receptor stabilization in humans. | Singh R et al. | — | 2013 | → |
| MAP3K7 and GSTZ1 are associated with human longevity: a two-stage case-control study using a multilocus genotyping. | Di Cianni F et al. | — | 2013 | → |
| MetaSeq: privacy preserving meta-analysis of sequencing-based association studies. | Singh AP et al. | — | 2013 | → |
| Mutations in Mll2, an H3K4 methyltransferase, result in insulin resistance and impaired glucose tolerance in mice. | Goldsworthy M et al. | — | 2013 | → |
| New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. | Horikoshi M et al. | — | 2013 | → |
| No detectable association of IGF2BP2 and SLC30A8 genes with type 2 diabetes in the population of Hyderabad, India. | Kommoju UJ et al. | — | 2013 | → |
| Nor-1, a novel incretin-responsive regulator of insulin genes and insulin secretion. | Ordelheide AM et al. | — | 2013 | → |
| Novel susceptibility genes associated with diabetic cataract in a Taiwanese population. | Lin HJ et al. | — | 2013 | → |
| On association analysis of rare variants under population substructure: an approach for the detection of subjects that can cause bias in the analysis--T opt: an outlier detection method. | Qiao D et al. | — | 2013 | → |
| Overview of Genomic Insights into Chicken Growth Traits Based on Genome-Wide Association Study and microRNA Regulation. | Xu Z et al. | — | 2013 | → |
| Positive regulation of insulin signaling by neuraminidase 1. | Dridi L et al. | — | 2013 | → |
| Predicting disease risk using bootstrap ranking and classification algorithms. | Manor O et al. | — | 2013 | → |
| Privacy-Preserving Data Exploration in Genome-Wide Association Studies. | Johnson A et al. | — | 2013 | → |
| Rank-based robust tests for quantitative-trait genetic association studies. | Li Q et al. | — | 2013 | → |
| Rare nonconservative LRP6 mutations are associated with metabolic syndrome. | Singh R et al. | — | 2013 | → |
| Recent progress in the use of genetics to understand links between type 2 diabetes and related metabolic traits. | Yaghootkar H et al. | — | 2013 | → |
| Regulation of insulin synthesis and secretion and pancreatic Beta-cell dysfunction in diabetes. | Fu Z et al. | — | 2013 | → |
| Replication of type 2 diabetes candidate genes variations in three geographically unrelated Indian population groups. | Ali S et al. | — | 2013 | → |
| Replication study for the association of 9 East Asian GWAS-derived loci with susceptibility to type 2 diabetes in a Japanese population. | Sakai K et al. | — | 2013 | → |
| Replication study for the association of a single-nucleotide polymorphism, rs3746876, within KCNJ15, with susceptibility to type 2 diabetes in a Japanese population. | Fukuda H et al. | — | 2013 | → |
| RNAi screening in primary human hepatocytes of genes implicated in genome-wide association studies for roles in type 2 diabetes identifies roles for CAMK1D and CDKAL1, among others, in hepatic glucose regulation. | Haney S et al. | — | 2013 | → |
| Robust joint analysis with data fusion in two-stage quantitative trait genome-wide association studies. | Pan DD et al. | — | 2013 | → |
| SNP selection in genome-wide association studies via penalized support vector machine with MAX test. | Kim J et al. | — | 2013 | → |
| Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes. | Snogdal LS et al. | — | 2013 | → |
| Study design of DIACORE (DIAbetes COhoRtE) - a cohort study of patients with diabetes mellitus type 2. | Dörhöfer L et al. | — | 2013 | → |
| Suggestive evidence for association between L-type voltage-gated calcium channel (CACNA1C) gene haplotypes and bipolar disorder in Latinos: a family-based association study. | Gonzalez S et al. | — | 2013 | → |
| Systematic evaluation of validated type 2 diabetes and glycaemic trait loci for association with insulin clearance. | Goodarzi MO et al. | — | 2013 | → |
| Systematic identification of interaction effects between genome- and environment-wide associations in type 2 diabetes mellitus. | Patel CJ et al. | — | 2013 | → |
| TCF7L2 gene polymorphisms and type 2 diabetes risk: a comprehensive and updated meta-analysis involving 121,174 subjects. | Peng S et al. | — | 2013 | → |
| The association of genetic markers for type 2 diabetes with prediabetic status - cross-sectional data of a diabetes prevention trial. | Zyriax BC et al. | — | 2013 | → |
| The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance. | Tamaki M et al. | — | 2013 | → |
| The genetics of diabetic nephropathy. | Brennan E et al. | — | 2013 | → |
| The genetics of type 2 diabetes and its clinical relevance. | Pal A et al. | — | 2013 | → |
| The impact of improved microarray coverage and larger sample sizes on future genome-wide association studies. | Lindquist KJ et al. | — | 2013 | → |
| The new perspectives on genetic studies of type 2 diabetes and thyroid diseases. | Xu M et al. | — | 2013 | → |
| The required beta cell research for improving treatment of type 2 diabetes. | Thorens B | — | 2013 | → |
| The SLC30 family of zinc transporters - a review of current understanding of their biological and pathophysiological roles. | Huang L et al. | — | 2013 | → |
| Trans-ethnic fine mapping identifies a novel independent locus at the 3' end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population. | Kuo JZ et al. | — | 2013 | → |
| Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study. | Ng MC et al. | — | 2013 | → |
| ttm-1 encodes CDF transporters that excrete zinc from intestinal cells of C. elegans and act in a parallel negative feedback circuit that promotes homeostasis. | Roh HC et al. | — | 2013 | → |
| Use of net reclassification improvement (NRI) method confirms the utility of combined genetic risk score to predict type 2 diabetes. | Tam CH et al. | — | 2013 | → |
| What is the contribution of two genetic variants regulating VEGF levels to type 2 diabetes risk and to microvascular complications? | Bonnefond A et al. | — | 2013 | → |
| Zinc and glycemic control: a meta-analysis of randomised placebo controlled supplementation trials in humans. | Capdor J et al. | — | 2013 | → |
| Zinc as a potential coadjuvant in therapy for type 2 diabetes. | Ruz M et al. | — | 2013 | → |
| Zinc, insulin, and the liver: a ménage à trois. | O'Halloran TV et al. | — | 2013 | → |
| Zinc, pancreatic islet cell function and diabetes: new insights into an old story. | Chimienti F | — | 2013 | → |
| Zinc stabilization of prefibrillar oligomers of human islet amyloid polypeptide. | Brender JR et al. | — | 2013 | → |
| Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice. | da Silva Xavier G et al. | — | 2012 | → |
| Advanced research on risk factors of type 2 diabetes. | Bi Y et al. | — | 2012 | → |
| A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. | Manning AK et al. | — | 2012 | → |
| A highly sensitive and specific genetic marker to diagnose aspirin-exacerbated respiratory disease using a genome-wide association study. | Shin SW et al. | — | 2012 | → |
| A likelihood ratio-based Mann-Whitney approach finds novel replicable joint gene action for type 2 diabetes. | Lu Q et al. | — | 2012 | → |
| Analysis of common type 2 diabetes mellitus genetic risk factors in new-onset diabetes after transplantation in kidney transplant patients medicated with tacrolimus. | Kurzawski M et al. | — | 2012 | → |
| A novel method to identify high order gene-gene interactions in genome-wide association studies: gene-based MDR. | Oh S et al. | — | 2012 | → |
| Applying semantic web technologies for phenome-wide scan using an electronic health record linked Biobank. | Pathak J et al. | — | 2012 | → |
| A single nucleotide polymorphism within DUSP9 is associated with susceptibility to type 2 diabetes in a Japanese population. | Fukuda H et al. | — | 2012 | → |
| Association between autoantibodies to the Arginine variant of the Zinc transporter 8 (ZnT8) and stimulated C-peptide levels in Danish children and adolescents with newly diagnosed type 1 diabetes. | Andersen ML et al. | — | 2012 | → |
| Association of TCF7L2 and ADIPOQ with body mass index, waist-hip ratio, and systolic blood pressure in an endogamous ethnic group of India. | Gupta V et al. | — | 2012 | → |
| Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident coronary heart disease in a Hong Kong Chinese population. | Ho JS et al. | — | 2012 | → |
| Association of the rs7903146 single nucleotide polymorphism at the Transcription Factor 7-like 2 (TCF7L2) locus with type 2 diabetes in Brazilian subjects. | Barra GB et al. | — | 2012 | → |
| Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the Breast and Prostate Cancer Cohort Consortium. | Machiela MJ et al. | — | 2012 | → |
| A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets. | Taneera J et al. | — | 2012 | → |
| Autocrine regulation of insulin secretion. | Braun M et al. | — | 2012 | → |
| Bayes factor based on the trend test incorporating Hardy-Weinberg disequilibrium: more power to detect genetic association. | Xu J et al. | — | 2012 | → |
| Comparison of statistical tests for association between rare variants and binary traits. | Bacanu SA et al. | — | 2012 | → |
| Consistent directions of effect for established type 2 diabetes risk variants across populations: the population architecture using Genomics and Epidemiology (PAGE) Consortium. | Haiman CA et al. | — | 2012 | → |
| Contribution of common genetic variation to the risk of type 2 diabetes in the Mexican Mestizo population. | Gamboa-Meléndez MA et al. | — | 2012 | → |
| Current genomics in cardiovascular medicine. | Sawhney V et al. | — | 2012 | → |
| Cutting-edge issues in primary biliary cirrhosis. | Folci M et al. | — | 2012 | → |
| Dietary fiber intake increases the risk of zinc deficiency in healthy and diabetic women. | Foster M et al. | — | 2012 | → |
| Dietary zinc reduction, pyruvate supplementation, or zinc transporter 5 knockout attenuates β-cell death in nonobese diabetic mice, islets, and insulinoma cells. | Sheline CT et al. | — | 2012 | → |
| Epigenetic regulation of pancreas development and function. | Avrahami D et al. | — | 2012 | → |
| European American stratification in ovarian cancer case control data: the utility of genome-wide data for inferring ancestry. | Raska P et al. | — | 2012 | → |
| Evaluation of genome-wide association study-identified type 2 diabetes loci in African Americans. | Long J et al. | — | 2012 | → |
| Exercise and type 2 diabetes: new prescription for an old problem. | Bird SR et al. | — | 2012 | → |
| Exercise training, genetics and type 2 diabetes-related phenotypes. | Hagberg JM et al. | — | 2012 | → |
| Exome sequencing and the genetic basis of complex traits. | Kiezun A et al. | — | 2012 | → |
| Expression analyses of the genes harbored by the type 2 diabetes and pediatric BMI associated locus on 10q23. | Zhao J et al. | — | 2012 | → |
| Expression-based genome-wide association study links the receptor CD44 in adipose tissue with type 2 diabetes. | Kodama K et al. | — | 2012 | → |
| Female mice are protected against high-fat diet induced metabolic syndrome and increase the regulatory T cell population in adipose tissue. | Pettersson US et al. | — | 2012 | → |
| Finding genetic risk factors of gestational diabetes. | Kwak SH et al. | — | 2012 | → |
| From mice to humans. | McMurray F et al. | — | 2012 | → |
| Functional analysis of HapMap SNPs. | Liu CT et al. | — | 2012 | → |
| Functional role of intracellular labile zinc in pulmonary endothelium. | Thambiayya K et al. | — | 2012 | → |
| Further evidence for the association of genetic variants of ZNF804A with schizophrenia and a meta-analysis for genome-wide significance variant rs1344706. | Zhang R et al. | — | 2012 | → |
| Genetic association of zinc transporter 8 (ZnT8) autoantibodies in type 1 diabetes cases. | Howson JM et al. | — | 2012 | → |
| Genetic association studies in lumbar disc degeneration: a systematic review. | Eskola PJ et al. | — | 2012 | → |
| Genetic prediction of postpartum diabetes in women with gestational diabetes mellitus. | Ekelund M et al. | — | 2012 | → |
| Genetic risk score constructed using 14 susceptibility alleles for type 2 diabetes is associated with the early onset of diabetes and may predict the future requirement of insulin injections among Japanese individuals. | Iwata M et al. | — | 2012 | → |
| Genetics of type 2 diabetes in East Asian populations. | Cho YS et al. | — | 2012 | → |
| Genetics of type 2 diabetes in European populations. | Qi Q et al. | — | 2012 | → |
| Genetic variants near PDGFRA are associated with corneal curvature in Australians. | Mishra A et al. | — | 2012 | → |
| Genetic variants of IDE-KIF11-HHEX at 10q23.33 associated with type 2 diabetes risk: a fine-mapping study in Chinese population. | Qian Y et al. | — | 2012 | → |
| Genome-wide arrays: quality criteria and platforms to be used in routine diagnostics. | Vermeesch JR et al. | — | 2012 | → |
| Genome-wide meta-analysis of genetic susceptible genes for Type 2 Diabetes. | Hale PJ et al. | — | 2012 | → |
| Genomics is the medium for 21st century biology. | Scherer SW | — | 2012 | → |
| Genotype prediction of adult type 2 diabetes from adolescence in a multiracial population. | Vassy JL et al. | — | 2012 | → |
| Gestational diabetes mellitus: a positive predictor of type 2 diabetes? | Rice GE et al. | — | 2012 | → |
| Glucose-dependent regulation of NR2F2 promoter and influence of SNP-rs3743462 on whole body insulin sensitivity. | Boutant M et al. | — | 2012 | → |
| Hematopoietically-expressed homeobox gene three widely-evaluated polymorphisms and risk for diabetes: a meta-analysis. | Li X et al. | — | 2012 | → |
| Identification of shared genetic susceptibility locus for coronary artery disease, type 2 diabetes and obesity: a meta-analysis of genome-wide studies. | Wu C et al. | — | 2012 | → |
| IGF2BP2 alternative variants associated with glutamic acid decarboxylase antibodies negative diabetes in Malaysian subjects. | Salem SD et al. | — | 2012 | → |
| Impact of transcription factor 7-like 2 (TCF7L2) on pancreatic islet function and morphology in mice and men. | Renström E | — | 2012 | → |
| Importance of β-Catenin in glucose and energy homeostasis. | Elghazi L et al. | — | 2012 | → |
| Improving power of genome-wide association studies with weighted false discovery rate control and prioritized subset analysis. | Lin WY et al. | — | 2012 | → |
| Individualized therapy for type 2 diabetes: clinical implications of pharmacogenetic data. | Mannino GC et al. | — | 2012 | → |
| Inferring novel gene-disease associations using Medical Subject Heading Over-representation Profiles. | Cheung WA et al. | — | 2012 | → |
| Interactions between genetic background, insulin resistance and β-cell function. | Kahn SE et al. | — | 2012 | → |
| Investigation of allelic heterogeneity of the CCK-A receptor gene in paranoid schizophrenia. | Zheng C et al. | — | 2012 | → |
| Investigation on cardiovascular risk prediction using genetic information. | Pu LN et al. | — | 2012 | → |
| Is genetic testing useful to predict type 2 diabetes? | Vassy JL et al. | — | 2012 | → |
| Islet function in obese adolescents. | Giannini C et al. | — | 2012 | → |
| Joint effect of genetic and lifestyle risk factors on type 2 diabetes risk among Chinese men and women. | Villegas R et al. | — | 2012 | → |
| Lack of association between genetic polymorphisms within KCNQ1 locus and type 2 diabetes in Tunisian Arabs. | Turki A et al. | — | 2012 | → |
| Meta-analysis of association between the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-γ2 gene and diabetic retinopathy in Caucasians and Asians. | Ma J et al. | — | 2012 | → |
| Meta-analysis of the relationship between common type 2 diabetes risk gene variants with gestational diabetes mellitus. | Mao H et al. | — | 2012 | → |
| Mining the human phenome using semantic web technologies: a case study for Type 2 Diabetes. | Pathak J et al. | — | 2012 | → |
| MultiPhen: joint model of multiple phenotypes can increase discovery in GWAS. | O'Reilly PF et al. | — | 2012 | → |
| Novel association approach for variable number tandem repeats (VNTRs) identifies DOCK5 as a susceptibility gene for severe obesity. | El-Sayed Moustafa JS et al. | — | 2012 | → |
| Novel technologies for assessing dietary intake: evaluating the usability of a mobile telephone food record among adults and adolescents. | Daugherty BL et al. | — | 2012 | → |
| Pancreatic beta-cell function and type 2 diabetes risk: quantify the causal effect using a Mendelian randomization approach based on meta-analyses. | Song Y et al. | — | 2012 | → |
| Peptidomics approach to elucidate the proteolytic regulation of bioactive peptides. | Kim YG et al. | — | 2012 | → |
| Polycystic ovary syndrome is not associated with polymorphisms of the TCF7L2, CDKAL1, HHEX, KCNJ11, FTO and SLC30A8 genes. | Kim JJ et al. | — | 2012 | → |
| Prediction of Colorectal Cancer Risk Using a Genetic Risk Score: The Korean Cancer Prevention Study-II (KCPS-II). | Jo J et al. | — | 2012 | → |
| Randomized controlled trial of the effectiveness of genetic counseling and a distance, computer-based, lifestyle intervention program for adult offspring of patients with type 2 diabetes: background, study protocol, and baseline patient characteristics. | Nishigaki M et al. | — | 2012 | → |
| Randomized trial of personal genomics for preventive cardiology: design and challenges. | Knowles JW et al. | — | 2012 | → |
| Recent progress on type II diacylglycerol kinases: the physiological functions of diacylglycerol kinase δ, η and κ and their involvement in disease. | Sakai H et al. | — | 2012 | → |
| Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes. | Rosengren AH et al. | — | 2012 | → |
| Regulation and functional effects of ZNT8 in human pancreatic islets. | Lefebvre B et al. | — | 2012 | → |
| Response to comment on: Marquez et al. Low-frequency variants in HMGA1 are not associated with type 2 diabetes risk. Diabetes 2012;61:524-530. | Froguel P et al. | — | 2012 | → |
| Room for the candidate gene approach in the genome-wide association era: an example from GSTP1 gene polymorphism. | Mlynarski W | — | 2012 | → |
| Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes. | Mahdi T et al. | — | 2012 | → |
| SNP selection and classification of genome-wide SNP data using stratified sampling random forests. | Wu Q et al. | — | 2012 | → |
| Stratification-score matching improves correction for confounding by population stratification in case-control association studies. | Epstein MP et al. | — | 2012 | → |
| Technical reproducibility of genotyping SNP arrays used in genome-wide association studies. | Hong H et al. | — | 2012 | → |
| Ten SNPs of PAX6, Lumican, and MYOC genes are not associated with high myopia in Han Chinese. | Dai L et al. | — | 2012 | → |
| The evolution and refinement of traditional risk factors for cardiovascular disease. | deGoma EM et al. | — | 2012 | → |
| The genetic and epigenetic basis of type 2 diabetes and obesity. | Drong AW et al. | — | 2012 | → |
| The physiological effects of deleting the mouse SLC30A8 gene encoding zinc transporter-8 are influenced by gender and genetic background. | Pound LD et al. | — | 2012 | → |
| The rs11705701 G>A polymorphism of IGF2BP2 is associated with IGF2BP2 mRNA and protein levels in the visceral adipose tissue - a link to type 2 diabetes susceptibility. | Chistiakov DA et al. | — | 2012 | → |
| Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource. | Liu CT et al. | — | 2012 | → |
| Type 2 Diabetes Genetics: Beyond GWAS. | Sanghera DK et al. | — | 2012 | → |
| Tyrosine hydroxylase gene: another piece of the genetic puzzle of Parkinson's disease. | Bademci G et al. | — | 2012 | → |
| Understanding the elusive mechanism of action of TCF7L2 in metabolism. | Grant SF | — | 2012 | → |
| Using gene-network landscape to dissect genotype effects of TCF7L2 genetic variant on diabetes and cardiovascular risk. | Vaquero AR et al. | — | 2012 | → |
| Variations with modest effects have an important role in the genetic background of type 2 diabetes and diabetes-related traits. | Fujita H et al. | — | 2012 | → |
| Whole-genome sequencing in personalized therapeutics. | Cordero P et al. | — | 2012 | → |
| Widespread expression of zinc transporter ZnT (SLC30) family members in mouse endocrine cells. | Zhong ML et al. | — | 2012 | → |
| Zinc transporter 8 autoantibodies and their association with SLC30A8 and HLA-DQ genes differ between immigrant and Swedish patients with newly diagnosed type 1 diabetes in the Better Diabetes Diagnosis study. | Delli AJ et al. | — | 2012 | → |
| Zinc transporters and their role in the pancreatic β-cell. | Lemaire K et al. | — | 2012 | → |
| Zinc transporters, mechanisms of action and therapeutic utility: implications for type 2 diabetes mellitus. | Myers SA et al. | — | 2012 | → |