AMPK gene

Aliases: AMP-activated kinase, AMP-activated protein kinase, AMPK, AMPK signaling, PRKAA1, PRKAA1/PRKAA2 complex, PRKAA2, hypothalamic AMPK
External links: NCBI Gene · Ensembl · GeneCards · UniProt

Evidence from: primary | all sources

Related entities (39)

Subject	Relation	Object	p-value	Evidence
aging	regulates	AMPK	—	1
aging	associated_with	AMPK	—	1
AICAR	regulates	AMPK	—	1
AMP	regulates	AMPK	—	1
AMPK	interacts_with	AMP	—	1
AMPK	protective_against	anorexia nervosa	—	1
AMPK	expressed_in	ARC	—	1
AMPK	interacts_with	ATP	—	1
AMPK	regulates	energy expenditure	—	1
AMPK	regulates	energy homeostasis	—	1
AMPK	risk_factor_for	fatty liver	—	1
AMPK	regulates	feeding behavior	—	1
AMPK	expressed_in	hypothalamus	—	1
AMPK	protective_against	inflammation	—	1
AMPK	regulates	inflammation	—	1
AMPK	regulates	NF-κB	—	1
AMPK	interacts_with	nicotine	—	1
AMPK	regulates	NPY	—	1
AMPK	regulates	Pomc	—	1
AMPK	regulates	PPARGC1A	—	1
AMPK	regulates	SREBF1	—	1
AMPK	regulates	thermogenesis	—	1
AMPK	expressed_in	VMH	—	1
AMPK	targets	VMH	—	1
AMPK	associated_with	weight loss	—	1
AMPK	protective_against	weight loss	—	1
CAMKK2	targets	AMPK	—	1
ethanol group	regulates	AMPK	—	1
European ancestry	associated_with	AMPK	—	1
leptin	regulates	AMPK	—	1
mecamylamine	regulates	AMPK	—	1
Metformin	regulates	AMPK	—	1
Metformin	targets	AMPK	—	1
nicotine	regulates	AMPK	—	1
nicotine	interacts_with	AMPK	—	1
rosiglitazone	regulates	AMPK	—	1
STK11	targets	AMPK	—	1
stroke	regulates	AMPK	—	1
thiazolidinediones	targets	AMPK	—	1

Mentioned in (20)

Papers in which this entity is mentioned.

Splicing neoantigen discovery with SNAF reveals shared targets for cancer immunotherapy. (2024)
The landscape of drug sensitivity and resistance in sarcoma. (2024)
Alcohol exposure suppresses ribosome biogenesis and causes nucleolar stress in cranial neural crest cells. (2024)
Pathogenesis of Alcoholic Fatty Liver a Narrative Review. (2023)
Towards understandings of serine/arginine-rich splicing factors. (2023)
Rodent models in placental research. Implications for fetal origins of adult disease. (2022)
Beneficial Effects of Betaine: A Comprehensive Review. (2021)
Choline Kinase: An Unexpected Journey for a Precision Medicine Strategy in Human Diseases. (2021)
Transcriptome Profiling Identifies Ribosome Biogenesis as a Target of Alcohol Teratogenicity and Vulnerability during Early Embryogenesis. (2017)
Regulation of mTORC1 by PI3K signaling. (2015)
Cytochrome P450 1B1: An unexpected modulator of liver fatty acid homeostasis. (2015)
Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans. (2015)
The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease. (2014)
Alcohol metabolism and epigenetics changes. (2013)
Inflammaging: disturbed interplay between autophagy and inflammasomes. (2012)
Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase. (2012)
Regulation of chromatin by histone modifications. (2011)
Alcohol and PRAS40 knockdown decrease mTOR activity and protein synthesis via AMPK signaling and changes in mTORC1 interaction. (2010)
Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009)
Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity. (2005)

Merged raw entities (9)

All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.

Raw name	Type	Papers	Mentions
ampk	gene	15	44
ampk	drug	9	18
prkaa1	gene	4	5
prkaa2	gene	2	2
amp-activated kinase	gene	—	—
amp-activated protein kinase	gene	—	—
ampk signaling	gene	—	—
hypothalamic ampk	gene	—	—
prkaa1/prkaa2 complex	gene	—	—