AMPA receptor drug
Evidence from:
primary |
all sources
Related entities (16)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| alcohol | interacts_with | AMPA receptor | 0.19 | 1 |
| alcohol | regulates | AMPA receptor | — | 1 |
| AMPA receptor | expressed_in | basolateral amygdala | — | 1 |
| AMPA receptor | expressed_in | hippocampus | — | 1 |
| AMPA receptor | expressed_in | Purkinje cells | — | 1 |
| chronic ethanol exposure | regulates | AMPA receptor | — | 1 |
| CNQX | interacts_with | AMPA receptor | — | 1 |
| CNQX | targets | AMPA receptor | — | 2 |
| DNQX | interacts_with | AMPA receptor | — | 1 |
| DNQX | targets | AMPA receptor | — | 1 |
| d-serine | regulates | AMPA receptor | — | 1 |
| glutamate | regulates | AMPA receptor | — | 1 |
| glutamate | interacts_with | AMPA receptor | — | 1 |
| glutamate | targets | AMPA receptor | — | 2 |
| TNF | regulates | AMPA receptor | — | 1 |
| TNFα | regulates | AMPA receptor | — | 1 |
Mentioned in (39)
Papers in which this entity is mentioned.
- Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses. (2023)
- A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline. (2021)
- Development of a high-throughput arrayed neural circuitry platform using human induced neurons for drug screening applications. (2020)
- TGF-β/Smad3 Signalling Modulates GABA Neurotransmission: Implications in Parkinson's Disease. (2020)
- PKA and Ube3a regulate SK2 channel trafficking to promote synaptic plasticity in hippocampus: Implications for Angelman Syndrome. (2020)
- Mental Illnesses-Associated Fxr1 and Its Negative Regulator Gsk3β Are Modulators of Anxiety and Glutamatergic Neurotransmission. (2018)
- Does puberty mark a transition in sensitive periods for plasticity in the associative neocortex? (2017)
- Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice. (2017)
- ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease. (2017)
- Effect of Neuroinflammation on Synaptic Organization and Function in the Developing Brain: Implications for Neurodevelopmental and Neurodegenerative Disorders. (2017)
- H3K9me3 Inhibition Improves Memory, Promotes Spine Formation, and Increases BDNF Levels in the Aged Hippocampus. (2016)
- Experience-Dependent Accumulation of N6-Methyladenosine in the Prefrontal Cortex Is Associated with Memory Processes in Mice. (2016)
- Increasing the GluN2A/GluN2B Ratio in Neurons of the Mouse Basal and Lateral Amygdala Inhibits the Modification of an Existing Fear Memory Trace. (2016)
- Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings. (2016)
- Moderate prenatal alcohol exposure enhances GluN2B containing NMDA receptor binding and ifenprodil sensitivity in rat agranular insular cortex. (2015)
- GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics. (2014)
- Modeling hippocampal neurogenesis using human pluripotent stem cells. (2014)
- Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult mice. (2013)
- Adolescent chronic mild stress alters hippocampal CB1 receptor-mediated excitatory neurotransmission and plasticity. (2013)
- Rethinking schizophrenia in the context of normal neurodevelopment. (2013)
- Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus. (2013)
- Synaptic effects induced by alcohol. (2013)
- Pilot study of iPS-derived neural cells to examine biologic effects of alcohol on human neurons in vitro. (2012)
- Glutamatergic transmission in schizophrenia: from basic research to clinical practice. (2012)
- Fetal alcohol spectrum disorders and abnormal neuronal plasticity. (2011)
- The effects of a single memantine treatment on behavioral alterations associated with binge alcohol exposure in neonatal rats. (2011)
- How inhibition shapes cortical activity. (2011)
- Therapeutic utility of phosphodiesterase type I inhibitors in neurological conditions. (2011)
- Prenatal exposure to moderate levels of ethanol alters social behavior in adult rats: relationship to structural plasticity and immediate early gene expression in frontal cortex. (2010)
- Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration. (2010)
- Normal development of brain circuits. (2010)
- Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning. (2010)
- Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders. (2010)
- Neurotoxic effects and biomarkers of lead exposure: a review. (2009)
- Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. (2008)
- Acute ethanol suppresses glutamatergic neurotransmission through endocannabinoids in hippocampal neurons. (2008)
- Decline of the critical period of visual plasticity is concurrent with the reduction of NR2B subunit of the synaptic NMDA receptor in layer 4. (2003)
- Relationship between availability of NMDA receptor subunits and their expression at the synapse. (2002)
- Effect of enriched environment rearing on impairments in cortical excitability and plasticity after prenatal alcohol exposure. (1999)
Merged raw entities (5)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| ampa receptor | drug | 36 | 74 |
| ampa receptor | phenotype | 5 | 5 |
| ampa-receptor | drug | — | — |
| ampa receptor subunit | drug | — | — |
| glutamate receptor ampa | drug | — | — |