NMDA drug
Evidence from:
primary |
all sources
Related entities (12)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| alcohol | interacts_with | NMDA | — | 1 |
| animal models | associated_with | NMDA | — | 1 |
| DNQX | interacts_with | NMDA | — | 1 |
| ethanol group | targets | NMDA | — | 1 |
| glutamate | targets | NMDA | — | 1 |
| glycine | targets | NMDA | — | 1 |
| ketamine | interacts_with | NMDA | — | 1 |
| magnesium | interacts_with | NMDA | — | 1 |
| NMDA | associated_with | glutamate | — | 1 |
| NMDA | expressed_in | hippocampus | — | 1 |
| NMDA | regulates | MAPK3 | — | 1 |
| NMDA | associated_with | schizophrenia | — | 1 |
Mentioned in (59)
Papers in which this entity is mentioned.
- Reduction of APOE accounts for neurobehavioral deficits in fetal alcohol spectrum disorders. (2024)
- In utero exposure to HIV and/or antiretroviral therapy: a systematic review of preclinical and clinical evidence of cognitive outcomes. (2019)
- Transient Potassium Channels: Therapeutic Targets for Brain Disorders. (2019)
- SK Channel Modulates Synaptic Plasticity by Tuning CaMKIIα/β Dynamics. (2019)
- mTORC2 in the dorsomedial striatum of mice contributes to alcohol-dependent F-Actin polymerization, structural modifications, and consumption. (2018)
- Mental Illnesses-Associated Fxr1 and Its Negative Regulator Gsk3β Are Modulators of Anxiety and Glutamatergic Neurotransmission. (2018)
- Does puberty mark a transition in sensitive periods for plasticity in the associative neocortex? (2017)
- Alternative Polyadenylation Directs Tissue-Specific miRNA Targeting in Somatic Tissues. (2017)
- Sustained synchronized neuronal network activity in a human astrocyte co-culture system. (2016)
- Genetic Restoration of Plasma ApoE Improves Cognition and Partially Restores Synaptic Defects in ApoE-Deficient Mice. (2016)
- Thalamocortical Projections onto Behaviorally Relevant Neurons Exhibit Plasticity during Adult Motor Learning. (2016)
- Increasing the GluN2A/GluN2B Ratio in Neurons of the Mouse Basal and Lateral Amygdala Inhibits the Modification of an Existing Fear Memory Trace. (2016)
- Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings. (2016)
- An introductory review of parallel independent component analysis (p-ICA) and a guide to applying p-ICA to genetic data and imaging phenotypes to identify disease-associated biological pathways and systems in common complex disorders. (2015)
- Functional Connectivity Disruption in Neonates with Prenatal Marijuana Exposure. (2015)
- Aberrant development of post-movement beta rebound in adolescents and young adults with fetal alcohol spectrum disorders. (2015)
- Importance of genetics in fetal alcohol effects: null mutation of the nNOS gene worsens alcohol-induced cerebellar neuronal losses and behavioral deficits. (2015)
- Moderate prenatal alcohol exposure enhances GluN2B containing NMDA receptor binding and ifenprodil sensitivity in rat agranular insular cortex. (2015)
- Effects of Acute Prenatal Exposure to Ethanol on microRNA Expression are Ameliorated by Social Enrichment. (2014)
- Ethanol exposure induces neonatal neurodegeneration by enhancing CB1R Exon1 histone H4K8 acetylation and up-regulating CB1R function causing neurobehavioral abnormalities in adult mice. (2014)
- Long-term genomic and epigenomic dysregulation as a consequence of prenatal alcohol exposure: a model for fetal alcohol spectrum disorders. (2014)
- Low density lipoprotein receptor-related protein 1 (LRP1) modulates N-methyl-D-aspartate (NMDA) receptor-dependent intracellular signaling and NMDA-induced regulation of postsynaptic protein complexes. (2013)
- LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype. (2013)
- Interleukin-6 (IL-6) receptor/IL-6 fusion protein (Hyper IL-6) effects on the neonatal mouse brain: possible role for IL-6 trans-signaling in brain development and functional neurobehavioral outcomes. (2013)
- Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus. (2013)
- Interactive effects of dehydroepiandrosterone and testosterone on cortical thickness during early brain development. (2013)
- Long-lasting neural circuit dysfunction following developmental ethanol exposure. (2013)
- Alcohol-induced apoptosis of oligodendrocytes in the fetal macaque brain. (2013)
- The ubiquitin-proteasome system as a critical regulator of synaptic plasticity and long-term memory formation. (2013)
- Persistent dose-dependent changes in brain structure in young adults with low-to-moderate alcohol exposure in utero. (2012)
- Pilot study of iPS-derived neural cells to examine biologic effects of alcohol on human neurons in vitro. (2012)
- Glutamatergic transmission in schizophrenia: from basic research to clinical practice. (2012)
- Fetal alcohol exposure leads to abnormal olfactory bulb development and impaired odor discrimination in adult mice. (2011)
- Fetal alcohol spectrum disorders and abnormal neuronal plasticity. (2011)
- Protection of neurons and microglia against ethanol in a mouse model of fetal alcohol spectrum disorders by peroxisome proliferator-activated receptor-γ agonists. (2011)
- Memory for the order of events in specific sequences: contributions of the hippocampus and medial prefrontal cortex. (2011)
- Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation. (2010)
- Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning. (2010)
- Is there an inhibitory-response-control system in the rat? Evidence from anatomical and pharmacological studies of behavioral inhibition. (2010)
- Prenatal choline supplementation mitigates the adverse effects of prenatal alcohol exposure on development in rats. (2009)
- Phosphodiesterase inhibition increases CREB phosphorylation and restores orientation selectivity in a model of fetal alcohol spectrum disorders. (2009)
- Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence. (2009)
- Novel neuroprotective mechanisms of memantine: increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation. (2009)
- The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress. (2009)
- Protein kinases and addiction. (2008)
- Modeling the impact of alcohol on cortical development in a dish: strategies from mapping neural stem cell fate. (2008)
- Ethanol consumption during early pregnancy alters the disposition of tangentially migrating GABAergic interneurons in the fetal cortex. (2008)
- Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. (2008)
- Acute ethanol suppresses glutamatergic neurotransmission through endocannabinoids in hippocampal neurons. (2008)
- Maternal immune activation alters fetal brain development through interleukin-6. (2007)
- PIASx is a MEF2 SUMO E3 ligase that promotes postsynaptic dendritic morphogenesis. (2007)
- Decline of the critical period of visual plasticity is concurrent with the reduction of NR2B subunit of the synaptic NMDA receptor in layer 4. (2003)
- Neonatal alcohol exposure induces long-lasting impairment of visual cortical plasticity in ferrets. (2003)
- Relationship between availability of NMDA receptor subunits and their expression at the synapse. (2002)
- Anterograde amnesia and temporally graded retrograde amnesia for a nonspatial memory task after lesions of hippocampus and subiculum. (2002)
- In utero cocaine-induced dysfunction of dopamine D1 receptor signaling and abnormal differentiation of cerebral cortical neurons. (2000)
- Temporally graded retrograde amnesia of contextual fear after hippocampal damage in rats: within-subjects examination. (1999)
- Effect of enriched environment rearing on impairments in cortical excitability and plasticity after prenatal alcohol exposure. (1999)
- Trace eyeblink conditioning increases CA1 excitability in a transient and learning-specific manner. (1996)
Merged raw entities (3)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| nmda | drug | 56 | 111 |
| n-methyl-d-aspartate | drug | 5 | 6 |
| synthetic agonist nmda | drug | — | — |