shRNA drug

External links

DrugBank · PubChem

Related entities (1)

Mentioned in (25)

Papers in which this entity is mentioned.

• Integrated in vivo combinatorial functional genomics and spatial transcriptomics of tumours to decode genotype-to-phenotype relationships. (2026)
• FET fusion oncoproteins disrupt physiologic DNA repair and create a targetable opportunity for ATR inhibitor therapy. (2025)
• Multi-omic quantitative trait loci link tandem repeat size variation to gene regulation in human brain. (2025)
• Tracing the evolution of single-cell 3D genomes in Kras-driven cancers. (2025)
• Global impact of unproductive splicing on human gene expression. (2024)
• Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons. (2023)
• Macrophage Polarization States in the Tumor Microenvironment. (2021)
• Kcnn2 blockade reverses learning deficits in a mouse model of fetal alcohol spectrum disorders. (2020)
• Sequence, Structure, and Context Preferences of Human RNA Binding Proteins. (2018)
• Positively selected enhancer elements endow osteosarcoma cells with metastatic competence. (2018)
• EWS/FLI Confers Tumor Cell Synthetic Lethality to CDK12 Inhibition in Ewing Sarcoma. (2018)
• Statistical algorithms improve accuracy of gene fusion detection. (2017)
• Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain. (2017)
• Interaction of glycosphingolipids GD3 and GD2 with growth factor receptors maintains breast cancer stem cell phenotype. (2017)
• PGBD5 promotes site-specific oncogenic mutations in human tumors. (2017)
• Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing. (2015)
• MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens. (2014)
• CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma. (2014)
• Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis. (2014)
• EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma. (2014)
• Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer. (2013)
• Differential expression profiles of glycosphingolipids in human breast cancer stem cells vs. cancer non-stem cells. (2013)
• LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7. (2013)
• Novel mutations target distinct subgroups of medulloblastoma. (2012)
• An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells. (2009)

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