Shh gene

Aliases

SHH, SHH C25II, Sonic hedgehog, sonic hedgehog

External links

NCBI Gene · Ensembl · GeneCards · UniProt

No related entities found.

Mentioned in (40)

Papers in which this entity is mentioned.

• Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models. (2026)
• Human 3D brain organoids: steering the demolecularization of brain and neurological diseases. (2023)
• Gene-alcohol interactions in birth defects. (2023)
• High-throughput detection of craniofacial defects in fluorescent zebrafish. (2023)
• The pro-apoptotic Bax gene modifies susceptibility to craniofacial dysmorphology following gastrulation-stage alcohol exposure. (2022)
• Fetal Alcohol Spectrum Disorders: Awareness to Insight in Just 50 Years. (2022)
• Transcriptomic analyses of gastrulation-stage mouse embryos with differential susceptibility to alcohol. (2021)
• Exposure to ethanol leads to midfacial hypoplasia in a zebrafish model of FASD via indirect interactions with the Shh pathway. (2021)
• Prenatal alcohol exposure disrupts Sonic hedgehog pathway and primary cilia genes in the mouse neural tube. (2021)
• Multifactorial Genetic and Environmental Hedgehog Pathway Disruption Sensitizes Embryos to Alcohol-Induced Craniofacial Defects. (2020)
• Transcriptome-Wide Regulation of Key Developmental Pathways in the Mouse Neural Tube by Prenatal Alcohol Exposure. (2020)
• Novel Ethanol-Sensitive Mutants Identified in an F3 Forward Genetic Screen. (2020)
• Cannabinoids Exacerbate Alcohol Teratogenesis by a CB1-Hedgehog Interaction. (2019)
• Differentially sensitive neuronal subpopulations in the central nervous system and the formation of hindbrain heterotopias in ethanol-exposed zebrafish. (2019)
• Effects of prenatal alcohol exposure (PAE): insights into FASD using mouse models of PAE. (2018)
• Combined Face-Brain Morphology and Associated Neurocognitive Correlates in Fetal Alcohol Spectrum Disorders. (2018)
• Knockdown of Mns1 Increases Susceptibility to Craniofacial Defects Following Gastrulation-Stage Alcohol Exposure in Mice. (2018)
• Diving into the world of alcohol teratogenesis: a review of zebrafish models of fetal alcohol spectrum disorder. (2018)
• Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome. (2018)
• Genetic vulnerabilities to prenatal alcohol exposure: Limb defects in sonic hedgehog and GLI2 heterozygous mice. (2017)
• Gene-environment interactions in development and disease. (2017)
• Preaxial polydactyly following early gestational exposure to the smoothened agonist, SAG, in C57BL/6J mice. (2017)
• Pituitary lacks sexual dimorphism and displays reduced signal intensity on T1-weighted MRI in adolescents with histories of heavy prenatal alcohol exposure. (2016)
• An Fgf-Shh signaling hierarchy regulates early specification of the zebrafish skull. (2016)
• Pdgfra and Pdgfrb genetically interact during craniofacial development. (2016)
• Dose-dependent teratogenicity of the synthetic cannabinoid CP-55,940 in mice. (2016)
• The Genetics of Fetal Alcohol Spectrum Disorders. (2016)
• A screen of zebrafish mutants identifies ethanol-sensitive genetic loci. (2014)
• Characterization of subtle brain abnormalities in a mouse model of Hedgehog pathway antagonist-induced cleft lip and palate. (2014)
• The teratogenic effects of prenatal ethanol exposure are exacerbated by Sonic Hedgehog or GLI2 haploinsufficiency in the mouse. (2014)
• Developmental age strengthens barriers to ethanol accumulation in zebrafish. (2014)
• Commonality in Down and fetal alcohol syndromes. (2013)
• Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy. (2013)
• An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia. (2012)
• Ventromedian forebrain dysgenesis follows early prenatal ethanol exposure in mice. (2011)
• Agrin function associated with ocular development is a target of ethanol exposure in embryonic zebrafish. (2011)
• Cleft lip and palate results from Hedgehog signaling antagonism in the mouse: Phenotypic characterization and clinical implications. (2010)
• Genesis of teratogen-induced holoprosencephaly in mice. (2010)
• Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 7. (2010)
• The plausibility of maternal nutritional status being a contributing factor to the risk for fetal alcohol spectrum disorders: the potential influence of zinc status as an example. (2010)

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