heavy smoking phenotype
Evidence from:
primary |
all sources
Related entities (14)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| African-Americans | associated_with | heavy smoking | — | 1 |
| candidate genes | risk_factor_for | heavy smoking | — | 1 |
| Chrna3 | risk_factor_for | heavy smoking | — | 1 |
| Chrna3 | associated_with | heavy smoking | — | 3 |
| CHRNA5 | associated_with | heavy smoking | — | 4 |
| CHRNA5 | risk_factor_for | heavy smoking | — | 2 |
| Chrnb4 | risk_factor_for | heavy smoking | — | 1 |
| Chrnb4 | associated_with | heavy smoking | — | 3 |
| heavy smoking | associated_with | nicotine | — | 1 |
| heavy smoking | risk_factor_for | schizophrenia | — | 1 |
| rs1044396 | associated_with | heavy smoking | — | 1 |
| rs1051730 | associated_with | heavy smoking | — | 1 |
| rs1051730 | risk_factor_for | heavy smoking | 0.0003 | 2 |
| rs16969968 | risk_factor_for | heavy smoking | — | 3 |
Mentioned in (14)
Papers in which this entity is mentioned.
- Inferring gene expression from cell-free DNA fragmentation profiles. (2022)
- Human Genetics of Addiction: New Insights and Future Directions. (2018)
- G = E: What GWAS Can Tell Us about the Environment. (2016)
- Identification of CHRNA5 rare variants in African-American heavy smokers. (2014)
- Nominal association with CHRNA4 variants and nicotine dependence. (2013)
- Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking. (2013)
- The genetic basis of addictive disorders. (2012)
- Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. (2012)
- TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood. (2011)
- Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25. (2010)
- Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence. (2009)
- A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy. (2009)
- Genome-wide and candidate gene association study of cigarette smoking behaviors. (2009)
- Sociocultural influences on smoking and drinking. (2000)
Merged raw entities (2)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| heavy smoking | phenotype | 12 | 23 |
| heaviness of smoking | phenotype | 2 | 4 |