knockout mice cohort

Aliases: CHRNA5 knockout mice, Chrna5 knockouts, KO mice, knockout mice, α5 knockouts

Evidence from: primary | all sources

Related entities (15)

Subject	Relation	Object	p-value	Evidence
ethanol group	interacts_with	knockout mice	—	1
knockout mice	protective_against	cognition	—	1
knockout mice	interacts_with	ethanol group	0.05	1
knockout mice	associated_with	ethanol group	—	1
knockout mice	associated_with	locomotor activity	0.05	1
knockout mice	associated_with	loss of righting reflex	0.001	1
knockout mice	associated_with	motor coordination	—	1
knockout mice	associated_with	nicotine	—	1
knockout mice	associated_with	nicotine self-administration	—	1
knockout mice	associated_with	nicotine use	—	1
knockout mice	risk_factor_for	nicotine use	—	1
knockout mice	associated_with	Rotarod performance	0.01	1
knockout mice	associated_with	sedatives	0.001	1
knockout mice	associated_with	spatial memory	—	1
knockout mice	associated_with	sucrose	—	1

Mentioned in (19)

Papers in which this entity is mentioned.

Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons. (2023)
Genetics of substance use disorders in the era of big data. (2021)
ABHD4-dependent developmental anoikis safeguards the embryonic brain. (2020)
Neoadjuvant checkpoint blockade for cancer immunotherapy. (2020)
Knockdown of Mns1 Increases Susceptibility to Craniofacial Defects Following Gastrulation-Stage Alcohol Exposure in Mice. (2018)
Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice. (2017)
Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors. (2015)
CB1-receptor knockout neonatal mice are protected against ethanol-induced impairments of DNMT1, DNMT3A, and DNA methylation. (2015)
Polymorphisms in ABC transporter genes and concentrations of mercury in newborns--evidence from two Mediterranean birth cohorts. (2014)
Ethanol exposure induces neonatal neurodegeneration by enhancing CB1R Exon1 histone H4K8 acetylation and up-regulating CB1R function causing neurobehavioral abnormalities in adult mice. (2014)
Identification of CHRNA5 rare variants in African-American heavy smokers. (2014)
Deletion of the gabra2 gene results in hypersensitivity to the acute effects of ethanol but does not alter ethanol self administration. (2012)
Habenular α5 nicotinic receptor subunit signalling controls nicotine intake. (2011)
GABA A receptors: subtypes provide diversity of function and pharmacology. (2009)
Actions and interactions of alcohol and insulin-like growth factor-1 on female pubertal development. (2009)
The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress. (2009)
Protein kinases and addiction. (2008)
Perlecan controls neurogenesis in the developing telencephalon. (2007)
Biochemical and morphometric analyses show that myelination in the insulin-like growth factor 1 null brain is proportionate to its neuronal composition. (1998)

Merged raw entities (6)

All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.

Raw name	Type	Papers	Mentions
knockout mice	cohort	12	19
ko mice	cohort	7	30
α5 knockout mice	cohort	3	6
chrna5 knockout mice	cohort	1	1
chrna5 knockouts	cohort	—	—
α5 knockouts	cohort	—	—