Pax6 gene
Evidence from:
primary |
all sources
Related entities (18)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| Alexa Fluor 594 | interacts_with | Pax6 | — | 1 |
| BAF | interacts_with | Pax6 | — | 1 |
| Pax6 | interacts_with | BAF | — | 1 |
| Pax6 | biomarker_for | brain | — | 1 |
| Pax6 | interacts_with | BRG1 | — | 1 |
| Pax6 | expressed_in | lateral ganglionic eminence | — | 1 |
| Pax6 | expressed_in | LGE | — | 1 |
| Pax6 | expressed_in | medial ganglionic eminence | — | 1 |
| Pax6 | expressed_in | neocortex | — | 1 |
| Pax6 | expressed_in | neural stem cells | — | 1 |
| Pax6 | regulates | neurogenesis | — | 2 |
| Pax6 | regulates | neuronal differentiation | — | 1 |
| Pax6 | regulates | neurons | — | 1 |
| Pax6 | biomarker_for | OPCs | — | 1 |
| Pax6 | biomarker_for | schizophrenia | — | 1 |
| Pax6 | targets | SOX11 | — | 1 |
| Pax6 | expressed_in | telencephalon | — | 1 |
| Sox2 | associated_with | Pax6 | — | 1 |
Mentioned in (58)
Papers in which this entity is mentioned.
- LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development. (2025)
- Massively parallel reporter perturbation assays uncover temporal regulatory architecture during neural differentiation. (2022)
- Tead transcription factors differentially regulate cortical development. (2020)
- ABHD4-dependent developmental anoikis safeguards the embryonic brain. (2020)
- Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma. (2019)
- Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. (2018)
- Assembly of functionally integrated human forebrain spheroids. (2017)
- Single-Cell Profiling of an In Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation. (2017)
- Three Dimensional Human Neuro-Spheroid Model of Alzheimer's Disease Based on Differentiated Induced Pluripotent Stem Cells. (2016)
- Sustained synchronized neuronal network activity in a human astrocyte co-culture system. (2016)
- Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. (2016)
- Dose-dependent alcohol-induced alterations in chromatin structure persist beyond the window of exposure and correlate with fetal alcohol syndrome birth defects. (2015)
- Mechanisms of retinoic acid signalling and its roles in organ and limb development. (2015)
- Impact of prenatal environmental stress on cortical development. (2015)
- The role of BAF (mSWI/SNF) complexes in mammalian neural development. (2014)
- Induced neuronal reprogramming. (2014)
- Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. (2014)
- Gene expression signatures affected by alcohol-induced DNA methylomic deregulation in human embryonic stem cells. (2014)
- Fetal alcohol spectrum disorders and their transmission through genetic and epigenetic mechanisms. (2014)
- Modeling hippocampal neurogenesis using human pluripotent stem cells. (2014)
- Ethanol alters gene expression and cell organization during optic vesicle evagination. (2013)
- The sox family of transcription factors: versatile regulators of stem and progenitor cell fate. (2013)
- Prenatal ethanol exposure disrupts intraneocortical circuitry, cortical gene expression, and behavior in a mouse model of FASD. (2013)
- A critical role for PDGFRα signaling in medial nasal process development. (2013)
- Coordinated cell type-specific epigenetic remodeling in prefrontal cortex begins before birth and continues into early adulthood. (2013)
- Alcohol-induced epigenetic alterations to developmentally crucial genes regulating neural stemness and differentiation. (2013)
- Analysis of variation at transcription factor binding sites in Drosophila and humans. (2012)
- Does moderate drinking harm the fetal brain? Insights from animal models. (2012)
- Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives. (2012)
- SOX2 hypomorphism disrupts development of the prechordal floor and optic cup. (2012)
- Development of cortical surface area and gyrification in attention-deficit/hyperactivity disorder. (2012)
- Uberon, an integrative multi-species anatomy ontology. (2012)
- Mutations in Hedgehog acyltransferase (Hhat) perturb Hedgehog signaling, resulting in severe acrania-holoprosencephaly-agnathia craniofacial defects. (2012)
- Cdon mutation and fetal ethanol exposure synergize to produce midline signaling defects and holoprosencephaly spectrum disorders in mice. (2012)
- A small-molecule smoothened agonist prevents glucocorticoid-induced neonatal cerebellar injury. (2011)
- Agrin function associated with ocular development is a target of ethanol exposure in embryonic zebrafish. (2011)
- MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. (2011)
- S100B and APP promote a gliocentric shift and impaired neurogenesis in Down syndrome neural progenitors. (2011)
- How the timing and quality of early experiences influence the development of brain architecture. (2010)
- Fetal alcohol spectrum disorders: from research to policy. (2010)
- Dyrk1A overexpression inhibits proliferation and induces premature neuronal differentiation of neural progenitor cells. (2010)
- The basics of brain development. (2010)
- Sonic hedgehog ligand partners with caveolin-1 for intracellular transport. (2009)
- Novel SOX2 mutations and genotype-phenotype correlation in anophthalmia and microphthalmia. (2009)
- Pathogenesis of holoprosencephaly. (2009)
- DNA methylation and methyl-CpG binding proteins: developmental requirements and function. (2009)
- The embryonic preoptic area is a novel source of cortical GABAergic interneurons. (2009)
- Identification of novel mutations and sequence variants in the SOX2 and CHX10 genes in patients with anophthalmia/microphthalmia. (2008)
- Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly. (2008)
- An alcohol binding site on the neural cell adhesion molecule L1. (2008)
- Molecular specification and patterning of progenitor cells in the lateral and medial ganglionic eminences. (2008)
- Mechanisms for persistent microphthalmia following ethanol exposure during retinal neurogenesis in zebrafish embryos. (2007)
- Delineation of multiple subpallial progenitor domains by the combinatorial expression of transcriptional codes. (2007)
- Defects in eye development in transgenic mice overexpressing the heparan sulfate proteoglycan agrin. (2007)
- Defects in embryonic neurogenesis and initial synapse formation in the forebrain of the Ts65Dn mouse model of Down syndrome. (2007)
- Origin of oligodendrocytes in the subventricular zone of the adult brain. (2006)
- Origins of cortical interneuron subtypes. (2004)
- Visualization of cranial motor neurons in live transgenic zebrafish expressing green fluorescent protein under the control of the islet-1 promoter/enhancer. (2000)
Merged raw entities (2)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| pax6 | gene | 58 | 285 |
| paired box 6 | gene | — | — |