mTOR gene
Evidence from:
primary |
all sources
Related entities (7)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| caloric restriction | regulates | mTOR | — | 1 |
| mTOR | regulates | Autophagy | — | 1 |
| mTOR | regulates | inflammation | — | 1 |
| mTOR | associated_with | lifespan | — | 1 |
| mTOR | biomarker_for | tuberous sclerosis | — | 1 |
| rapamycin | targets | mTOR | — | 2 |
| TNF-α | regulates | mTOR | — | 1 |
Mentioned in (63)
Papers in which this entity is mentioned.
- Nanopore-based cell-free DNA fragmentation and methylation profiles from the cerebral spinal fluid of patients with lung cancer brain metastases. (2025)
- Zebrafish raptor mutation inhibits the activity of mTORC1, inducing craniofacial defects due to autophagy-induced neural crest cell death. (2024)
- Pathogenesis of Alcoholic Fatty Liver a Narrative Review. (2023)
- Towards understandings of serine/arginine-rich splicing factors. (2023)
- RNA splicing dysregulation and the hallmarks of cancer. (2023)
- Rodent models in placental research. Implications for fetal origins of adult disease. (2022)
- Integrating molecular profiles into clinical frameworks through the Molecular Oncology Almanac to prospectively guide precision oncology. (2021)
- Loss of tumor protein 53 protects against alcohol-induced facial malformations in mice and zebrafish. (2021)
- Macrophage Polarization States in the Tumor Microenvironment. (2021)
- Immuno-genomic landscape of osteosarcoma. (2020)
- Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy. (2019)
- Clinical presentation, diagnosis, and management of fetal alcohol spectrum disorder. (2019)
- How I diagnose and manage Philadelphia chromosome-like acute lymphoblastic leukemia. (2019)
- Genome-Informed Targeted Therapy for Osteosarcoma. (2019)
- Hippocampal deficits in neurodevelopmental disorders. (2019)
- mTORC2 in the dorsomedial striatum of mice contributes to alcohol-dependent F-Actin polymerization, structural modifications, and consumption. (2018)
- Detection of Somatic Structural Variants Enables Quantification and Characterization of Circulating Tumor DNA in Children With Solid Tumors. (2018)
- Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer. (2018)
- Comprehensive Characterization of Cancer Driver Genes and Mutations. (2018)
- PI3K Signaling in Neurons: A Central Node for the Control of Multiple Functions. (2018)
- Diving into the world of alcohol teratogenesis: a review of zebrafish models of fetal alcohol spectrum disorder. (2018)
- Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma. (2017)
- One-Carbon Metabolism in Health and Disease. (2017)
- Gene-environment interactions in development and disease. (2017)
- A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles. (2017)
- Transcriptome Profiling Identifies Ribosome Biogenesis as a Target of Alcohol Teratogenicity and Vulnerability during Early Embryogenesis. (2017)
- Fragment Length of Circulating Tumor DNA. (2016)
- The Placenta as a Mediator of Stress Effects on Neurodevelopmental Reprogramming. (2016)
- Alcohol Use During Pregnancy is Associated with Specific Alterations in MicroRNA Levels in Maternal Serum. (2016)
- Tissue-Specific Gene Repositioning by Muscle Nuclear Membrane Proteins Enhances Repression of Critical Developmental Genes during Myogenesis. (2016)
- Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia. (2016)
- The Genetics of Fetal Alcohol Spectrum Disorders. (2016)
- Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. (2015)
- Regulation of mTORC1 by PI3K signaling. (2015)
- MBASED: allele-specific expression detection in cancer tissues and cell lines. (2014)
- Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. (2014)
- Genomic factors that shape craniofacial outcome and neural crest vulnerability in FASD. (2014)
- Hepatic signaling by the mechanistic target of rapamycin complex 2 (mTORC2). (2014)
- Gene-ethanol interactions underlying fetal alcohol spectrum disorders. (2014)
- Long-term genomic and epigenomic dysregulation as a consequence of prenatal alcohol exposure: a model for fetal alcohol spectrum disorders. (2014)
- Cancer genome landscapes. (2013)
- Neurodevelopmental alcohol exposure elicits long-term changes to gene expression that alter distinct molecular pathways dependent on timing of exposure. (2013)
- Pdgfra protects against ethanol-induced craniofacial defects in a zebrafish model of FASD. (2013)
- Acute alcohol exposure, acidemia or glutamine administration impacts amino acid homeostasis in ovine maternal and fetal plasma. (2013)
- Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. (2013)
- The genomic landscape of hypodiploid acute lymphoblastic leukemia. (2013)
- The ubiquitin-proteasome system as a critical regulator of synaptic plasticity and long-term memory formation. (2013)
- Inflammaging: disturbed interplay between autophagy and inflammasomes. (2012)
- Patient-derived tumour xenografts as models for oncology drug development. (2012)
- DISC1 at 10: connecting psychiatric genetics and neuroscience. (2011)
- A syndrome of short stature, microcephaly and speech delay is associated with duplications reciprocal to the common Sotos syndrome deletion. (2010)
- Linking functional decline of telomeres, mitochondria and stem cells during ageing. (2010)
- Histone methylation regulates memory formation. (2010)
- The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes. (2010)
- Cellular metabolic stress: considering how cells respond to nutrient excess. (2010)
- Alcohol and PRAS40 knockdown decrease mTOR activity and protein synthesis via AMPK signaling and changes in mTORC1 interaction. (2010)
- Sexual dimorphism in the white matter of rodents. (2009)
- Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. (2008)
- Spatial genetic patterning of the embryonic neuroepithelium generates GABAergic interneuron diversity in the adult cortex. (2007)
- Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity. (2005)
- Origins of cortical interneuron subtypes. (2004)
- Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms. (2003)
- Myelination is altered in insulin-like growth factor-I null mutant mice. (2002)
Merged raw entities (2)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| mtor | gene | 63 | 172 |
| mammalian target of rapamycin | gene | 1 | 1 |