colorectal cancer phenotype

Aliases

CRC, colorectal, colorectum

No related entities found.

Mentioned in (109)

Papers in which this entity is mentioned.

• A guide to transcriptomic deconvolution in cancer. (2026)
• Comprehensive repertoire of the chromosomal alteration and mutational signatures across 16 cancer types. (2026)
• Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics. (2026)
• Enhancer activation from transposable elements in extrachromosomal DNA. (2025)
• Nanopore-based cell-free DNA fragmentation and methylation profiles from the cerebral spinal fluid of patients with lung cancer brain metastases. (2025)
• DrBioRight 2.0: an LLM-powered bioinformatics chatbot for large-scale cancer functional proteomics analysis. (2025)
• Chromosomal instability as a driver of cancer progression. (2025)
• Functional analysis of cancer-associated germline risk variants. (2025)
• Flexynesis: A deep learning toolkit for bulk multi-omics data integration for precision oncology and beyond. (2025)
• Transcription start sites experience a high influx of heritable variants fueled by early development. (2025)
• Recent advances in polygenic scores: translation, equitability, methods and FAIR tools. (2024)
• Insights for precision oncology from the integration of genomic and clinical data of 13,880 tumors from the 100,000 Genomes Cancer Programme. (2024)
• Analysis of 10,478 cancer genomes identifies candidate driver genes and opportunities for precision oncology. (2024)
• The Application of Long-Read Sequencing to Cancer. (2024)
• A New Era of Data-Driven Cancer Research and Care: Opportunities and Challenges. (2024)
• A Novel Tissue-Free Method to Estimate Tumor-Derived Cell-Free DNA Quantity Using Tumor Methylation Patterns. (2023)
• Desmoplastic stromal signatures predict patient outcomes in pancreatic ductal adenocarcinoma. (2023)
• Comprehensive repertoire of the chromosomal alteration and mutational signatures across 16 cancer types from 10,983 cancer patients (2023)
• Heritable defects in telomere and mitotic function selectively predispose to sarcomas. (2023)
• Machine learning for genetics-based classification and treatment response prediction in cancer of unknown primary. (2023)
• Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors. (2023)
• Single-molecule methylation profiles of cell-free DNA in cancer with nanopore sequencing. (2023)
• Towards understandings of serine/arginine-rich splicing factors. (2023)
• RNA splicing dysregulation and the hallmarks of cancer. (2023)
• Genome-wide mutational signatures in low-coverage whole genome sequencing of cell-free DNA. (2022)
• Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression. (2022)
• Spatially resolved whole transcriptome profiling in human and mouse tissue using Digital Spatial Profiling. (2022)
• Construction and validation of a novel gene signature for predicting the prognosis of osteosarcoma. (2022)
• Circulating Tumor DNA as a Biomarker in Patients With Stage III and IV Wilms Tumor: Analysis From a Children's Oncology Group Trial, AREN0533. (2022)
• Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors. (2021)
• Nanopore sequencing technology, bioinformatics and applications. (2021)
• Application of third-generation sequencing in cancer research. (2021)
• Evaluating the transcriptional fidelity of cancer models. (2021)
• Therapeutic Implications of Germline Testing in Patients With Advanced Cancers. (2021)
• Detection and characterization of lung cancer using cell-free DNA fragmentomes. (2021)
• Macrophage Polarization States in the Tumor Microenvironment. (2021)
• Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring. (2020)
• Pan-cancer analysis of whole genomes. (2020)
• Multi-cancer analysis of clonality and the timing of systemic spread in paired primary tumors and metastases. (2020)
• Emerging Roles of SRSF3 as a Therapeutic Target for Cancer. (2020)
• The repertoire of mutational signatures in human cancer. (2020)
• Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma. (2020)
• Cancer PRSweb: An Online Repository with Polygenic Risk Scores for Major Cancer Traits and Their Evaluation in Two Independent Biobanks. (2020)
• Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors. (2020)
• Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers. (2019)
• CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. (2019)
• Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy. (2019)
• Tumor mutational burden standardization initiatives: Recommendations for consistent tumor mutational burden assessment in clinical samples to guide immunotherapy treatment decisions. (2019)
• Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study. (2019)
• Germline variants associated with leukocyte genes predict tumor recurrence in breast cancer patients. (2019)
• Genome-wide cell-free DNA fragmentation in patients with cancer. (2019)
• RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues. (2019)
• Pan-cancer whole-genome analyses of metastatic solid tumours. (2019)
• Identifying simultaneous rearrangements in cancer genomes. (2018)
• Detection of Somatic Structural Variants Enables Quantification and Characterization of Circulating Tumor DNA in Children With Solid Tumors. (2018)
• Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer. (2018)
• Enhanced detection of circulating tumor DNA by fragment size analysis. (2018)
• Genome doubling shapes the evolution and prognosis of advanced cancers. (2018)
• Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes. (2018)
• Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes (2018)
• Molecular profiling and sequential somatic mutation shift in hypermutator tumours harbouring POLE mutations. (2018)
• Thymic involution and rising disease incidence with age. (2018)
• Copy number signatures and mutational processes in ovarian carcinoma. (2018)
• OncoKB: A Precision Oncology Knowledge Base. (2017)
• The evolution of tumour phylogenetics: principles and practice. (2017)
• Universal Patterns of Selection in Cancer and Somatic Tissues. (2017)
• Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors. (2017)
• Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients. (2017)
• Comprehensive Analysis of Hypermutation in Human Cancer. (2017)
• B lymphocytes and cancer: a love-hate relationship. (2016)
• Fragment Length of Circulating Tumor DNA. (2016)
• Comprehensive analyses of tumor immunity: implications for cancer immunotherapy. (2016)
• Development and clinical application of an integrative genomic approach to personalized cancer therapy. (2016)
• Estimating the population abundance of tissue-infiltrating immune and stromal cell populations using gene expression. (2016)
• Quantifying Clonal and Subclonal Passenger Mutations in Cancer Evolution. (2016)
• Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. (2015)
• ENVE: a novel computational framework characterizes copy-number mutational landscapes in colorectal cancers from African American patients. (2015)
• A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis. (2015)
• Clock-like mutational processes in human somatic cells. (2015)
• Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing. (2015)
• Hidden Markov Model-Based CNV Detection Algorithms for Illumina Genotyping Microarrays. (2014)
• MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens. (2014)
• Inference of high resolution HLA types using genome-wide RNA or DNA sequencing reads. (2014)
• MSIsensor: microsatellite instability detection using paired tumor-normal sequence data. (2014)
• OptiType: precision HLA typing from next-generation sequencing data. (2014)
• Inferring tumour purity and stromal and immune cell admixture from expression data. (2013)
• Cancer genome landscapes. (2013)
• Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability. (2013)
• Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. (2013)
• Signatures of mutational processes in human cancer. (2013)
• Fusion genes and their discovery using high throughput sequencing. (2013)
• Mutational heterogeneity in cancer and the search for new cancer-associated genes. (2013)
• Emerging landscape of oncogenic signatures across human cancers. (2013)
• Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples. (2013)
• RNA splicing: a new player in the DNA damage response. (2013)
• An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers. (2013)
• Differential expression profiles of glycosphingolipids in human breast cancer stem cells vs. cancer non-stem cells. (2013)
• Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy. (2013)
• Pan-cancer patterns of somatic copy number alteration. (2013)
• LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7. (2013)
• Absolute quantification of somatic DNA alterations in human cancer. (2012)
• Myeloid cells in tumor inflammation. (2012)
• Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma. (2012)
• Patient-derived tumour xenografts as models for oncology drug development. (2012)
• Massive genomic rearrangement acquired in a single catastrophic event during cancer development. (2011)
• Integrative analysis of the melanoma transcriptome. (2010)
• Germline BRAF mutations in Noonan, LEOPARD, and cardiofaciocutaneous syndromes: molecular diversity and associated phenotypic spectrum. (2009)
• 3' end mRNA processing: molecular mechanisms and implications for health and disease. (2008)
• Sequence variant classification and reporting: recommendations for improving the interpretation of cancer susceptibility genetic test results. (2008)

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