colorectal cancer phenotype
Evidence from:
primary |
all sources
Related entities (3)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| mutations | risk_factor_for | colorectal cancer | — | 1 |
| obesity | risk_factor_for | colorectal cancer | — | 1 |
| racial groups | associated_with | colorectal cancer | — | 1 |
Mentioned in (140)
Papers in which this entity is mentioned.
- A guide to transcriptomic deconvolution in cancer. (2026)
- Comprehensive repertoire of the chromosomal alteration and mutational signatures across 16 cancer types. (2026)
- Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics. (2026)
- Enhancer activation from transposable elements in extrachromosomal DNA. (2025)
- Nanopore-based cell-free DNA fragmentation and methylation profiles from the cerebral spinal fluid of patients with lung cancer brain metastases. (2025)
- DrBioRight 2.0: an LLM-powered bioinformatics chatbot for large-scale cancer functional proteomics analysis. (2025)
- Chromosomal instability as a driver of cancer progression. (2025)
- Functional analysis of cancer-associated germline risk variants. (2025)
- Flexynesis: A deep learning toolkit for bulk multi-omics data integration for precision oncology and beyond. (2025)
- Transcription start sites experience a high influx of heritable variants fueled by early development. (2025)
- Recent advances in polygenic scores: translation, equitability, methods and FAIR tools. (2024)
- Insights for precision oncology from the integration of genomic and clinical data of 13,880 tumors from the 100,000 Genomes Cancer Programme. (2024)
- Analysis of 10,478 cancer genomes identifies candidate driver genes and opportunities for precision oncology. (2024)
- The Application of Long-Read Sequencing to Cancer. (2024)
- A New Era of Data-Driven Cancer Research and Care: Opportunities and Challenges. (2024)
- A Novel Tissue-Free Method to Estimate Tumor-Derived Cell-Free DNA Quantity Using Tumor Methylation Patterns. (2023)
- Desmoplastic stromal signatures predict patient outcomes in pancreatic ductal adenocarcinoma. (2023)
- Comprehensive repertoire of the chromosomal alteration and mutational signatures across 16 cancer types from 10,983 cancer patients (2023)
- An overview of DNA methylation-derived trait score methods and applications. (2023)
- Heritable defects in telomere and mitotic function selectively predispose to sarcomas. (2023)
- Machine learning for genetics-based classification and treatment response prediction in cancer of unknown primary. (2023)
- Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors. (2023)
- Single-molecule methylation profiles of cell-free DNA in cancer with nanopore sequencing. (2023)
- Towards understandings of serine/arginine-rich splicing factors. (2023)
- RNA splicing dysregulation and the hallmarks of cancer. (2023)
- Genome-wide mutational signatures in low-coverage whole genome sequencing of cell-free DNA. (2022)
- Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression. (2022)
- Cross-tissue transcriptome-wide association studies identify susceptibility genes shared between schizophrenia and inflammatory bowel disease. (2022)
- Spatially resolved whole transcriptome profiling in human and mouse tissue using Digital Spatial Profiling. (2022)
- Construction and validation of a novel gene signature for predicting the prognosis of osteosarcoma. (2022)
- Circulating Tumor DNA as a Biomarker in Patients With Stage III and IV Wilms Tumor: Analysis From a Children's Oncology Group Trial, AREN0533. (2022)
- Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors. (2021)
- Nanopore sequencing technology, bioinformatics and applications. (2021)
- Application of third-generation sequencing in cancer research. (2021)
- Evaluating the transcriptional fidelity of cancer models. (2021)
- Therapeutic Implications of Germline Testing in Patients With Advanced Cancers. (2021)
- Detection and characterization of lung cancer using cell-free DNA fragmentomes. (2021)
- Choline Kinase: An Unexpected Journey for a Precision Medicine Strategy in Human Diseases. (2021)
- Macrophage Polarization States in the Tumor Microenvironment. (2021)
- Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring. (2020)
- Pan-cancer analysis of whole genomes. (2020)
- Multi-cancer analysis of clonality and the timing of systemic spread in paired primary tumors and metastases. (2020)
- Emerging Roles of SRSF3 as a Therapeutic Target for Cancer. (2020)
- The repertoire of mutational signatures in human cancer. (2020)
- Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma. (2020)
- Cancer PRSweb: An Online Repository with Polygenic Risk Scores for Major Cancer Traits and Their Evaluation in Two Independent Biobanks. (2020)
- Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors. (2020)
- Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers. (2019)
- CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. (2019)
- Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy. (2019)
- Tumor mutational burden standardization initiatives: Recommendations for consistent tumor mutational burden assessment in clinical samples to guide immunotherapy treatment decisions. (2019)
- Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study. (2019)
- Germline variants associated with leukocyte genes predict tumor recurrence in breast cancer patients. (2019)
- Genome-wide cell-free DNA fragmentation in patients with cancer. (2019)
- RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues. (2019)
- Pan-cancer whole-genome analyses of metastatic solid tumours. (2019)
- Identifying simultaneous rearrangements in cancer genomes. (2018)
- Detection of Somatic Structural Variants Enables Quantification and Characterization of Circulating Tumor DNA in Children With Solid Tumors. (2018)
- Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer. (2018)
- Enhanced detection of circulating tumor DNA by fragment size analysis. (2018)
- Genome doubling shapes the evolution and prognosis of advanced cancers. (2018)
- Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes. (2018)
- Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes (2018)
- Molecular profiling and sequential somatic mutation shift in hypermutator tumours harbouring POLE mutations. (2018)
- Thymic involution and rising disease incidence with age. (2018)
- Copy number signatures and mutational processes in ovarian carcinoma. (2018)
- Demystifying the cytokine network: Mathematical models point the way. (2017)
- OncoKB: A Precision Oncology Knowledge Base. (2017)
- The evolution of tumour phylogenetics: principles and practice. (2017)
- Universal Patterns of Selection in Cancer and Somatic Tissues. (2017)
- One-Carbon Metabolism in Health and Disease. (2017)
- Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors. (2017)
- Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients. (2017)
- Impact of cytosine methylation on DNA binding specificities of human transcription factors. (2017)
- Comprehensive Analysis of Hypermutation in Human Cancer. (2017)
- B lymphocytes and cancer: a love-hate relationship. (2016)
- Fragment Length of Circulating Tumor DNA. (2016)
- Alteration of Gene Expression, DNA Methylation, and Histone Methylation in Free Radical Scavenging Networks in Adult Mouse Hippocampus following Fetal Alcohol Exposure. (2016)
- Substantial contribution of extrinsic risk factors to cancer development. (2016)
- Comprehensive analyses of tumor immunity: implications for cancer immunotherapy. (2016)
- Development and clinical application of an integrative genomic approach to personalized cancer therapy. (2016)
- Epidemiology, Etiology, and Treatment of Isolated Cleft Palate. (2016)
- Estimating the population abundance of tissue-infiltrating immune and stromal cell populations using gene expression. (2016)
- Quantifying Clonal and Subclonal Passenger Mutations in Cancer Evolution. (2016)
- Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. (2015)
- ENVE: a novel computational framework characterizes copy-number mutational landscapes in colorectal cancers from African American patients. (2015)
- A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis. (2015)
- Clock-like mutational processes in human somatic cells. (2015)
- Time to First Morning Cigarette and Risk of Chronic Obstructive Pulmonary Disease: Smokers in the PLCO Cancer Screening Trial. (2015)
- Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing. (2015)
- Hidden Markov Model-Based CNV Detection Algorithms for Illumina Genotyping Microarrays. (2014)
- MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens. (2014)
- Inference of high resolution HLA types using genome-wide RNA or DNA sequencing reads. (2014)
- MSIsensor: microsatellite instability detection using paired tumor-normal sequence data. (2014)
- OptiType: precision HLA typing from next-generation sequencing data. (2014)
- Inferring tumour purity and stromal and immune cell admixture from expression data. (2013)
- Cancer genome landscapes. (2013)
- Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability. (2013)
- Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. (2013)
- Visualizing genomic information across chromosomes with PhenoGram. (2013)
- Signatures of mutational processes in human cancer. (2013)
- Fusion genes and their discovery using high throughput sequencing. (2013)
- Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples. (2013)
- Mutational heterogeneity in cancer and the search for new cancer-associated genes. (2013)
- Emerging landscape of oncogenic signatures across human cancers. (2013)
- Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples. (2013)
- RNA splicing: a new player in the DNA damage response. (2013)
- An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers. (2013)
- Differential expression profiles of glycosphingolipids in human breast cancer stem cells vs. cancer non-stem cells. (2013)
- Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy. (2013)
- Pan-cancer patterns of somatic copy number alteration. (2013)
- The Genomic Revolution and Beliefs about Essential Racial Differences: A Backdoor to Eugenics? (2013)
- Gene-environment interactions in cancer epidemiology: a National Cancer Institute Think Tank report. (2013)
- LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7. (2013)
- Absolute quantification of somatic DNA alterations in human cancer. (2012)
- Myeloid cells in tumor inflammation. (2012)
- Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma. (2012)
- Patient-derived tumour xenografts as models for oncology drug development. (2012)
- Massive genomic rearrangement acquired in a single catastrophic event during cancer development. (2011)
- Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. (2011)
- A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories. (2011)
- Regulation of chromatin by histone modifications. (2011)
- Down syndrome: searching for the genetic culprits. (2011)
- Significant differences in global genomic DNA methylation by gender and race/ethnicity in peripheral blood. (2011)
- Alcohol consumption and non-communicable diseases: epidemiology and policy implications. (2011)
- Distribution of allele frequencies and effect sizes and their interrelationships for common genetic susceptibility variants. (2011)
- Integrative analysis of the melanoma transcriptome. (2010)
- MicroRNAs: master regulators of ethanol abuse and toxicity? (2010)
- Network of Cancer Genes: a web resource to analyze duplicability, orthology and network properties of cancer genes. (2010)
- Gene--environment-wide association studies: emerging approaches. (2010)
- Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study. (2009)
- A groupwise association test for rare mutations using a weighted sum statistic. (2009)
- Genomewide association studies: history, rationale, and prospects for psychiatric disorders. (2009)
- Germline BRAF mutations in Noonan, LEOPARD, and cardiofaciocutaneous syndromes: molecular diversity and associated phenotypic spectrum. (2009)
- DNA methylation and methyl-CpG binding proteins: developmental requirements and function. (2009)
- Common and rare variants in multifactorial susceptibility to common diseases. (2008)
- 3' end mRNA processing: molecular mechanisms and implications for health and disease. (2008)
- Sequence variant classification and reporting: recommendations for improving the interpretation of cancer susceptibility genetic test results. (2008)
- Competing interactions between micro-RNAs determine neural progenitor survival and proliferation after ethanol exposure: evidence from an ex vivo model of the fetal cerebral cortical neuroepithelium. (2007)
- Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis. (1995)
Merged raw entities (4)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| colorectal cancer | phenotype | 137 | 382 |
| crc | phenotype | 10 | 21 |
| colorectal | phenotype | 6 | 6 |
| colorectum | phenotype | — | — |