CACNA1C gene
Evidence from:
primary |
all sources
Related entities (17)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| ADCY3 | interacts_with | CACNA1C | — | 1 |
| CACNA1C | associated_with | bipolar disorder | — | 4 |
| CACNA1C | risk_factor_for | bipolar disorder | 7e-08 | 5 |
| CACNA1C | regulates | calcium signaling | — | 1 |
| CACNA1C | associated_with | DD | — | 1 |
| CACNA1C | associated_with | mood disorders | — | 1 |
| CACNA1C | associated_with | neurodevelopmental disorder | — | 1 |
| CACNA1C | associated_with | neuropsychiatric disorders | 7e-08 | 1 |
| CACNA1C | associated_with | Psychiatric Genomics Consortium | 0.03 | 1 |
| CACNA1C | associated_with | psychiatric traits | — | 1 |
| CACNA1C | associated_with | schizophrenia | 0.01 | 4 |
| CACNA1C | risk_factor_for | schizophrenia | — | 4 |
| CACNA1C | risk_factor_for | Timothy syndrome | — | 2 |
| CACNA1C | associated_with | Timothy syndrome | — | 1 |
| CACNA1C | interacts_with | voltage-gated calcium channel | — | 1 |
| MIR137 | targets | CACNA1C | — | 2 |
| Timothy syndrome | associated_with | CACNA1C | — | 1 |
Mentioned in (32)
Papers in which this entity is mentioned.
- Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals. (2023)
- Mapping genomic loci implicates genes and synaptic biology in schizophrenia. (2022)
- Prenatal Adversity Alters the Epigenetic Profile of the Prefrontal Cortex: Sexually Dimorphic Effects of Prenatal Alcohol Exposure and Food-Related Stress. (2021)
- Alternative splicing: Human disease and quantitative analysis from high-throughput sequencing. (2021)
- Gene Expression in Patient-Derived Neural Progenitors Implicates WNT5A Signaling in the Etiology of Schizophrenia. (2020)
- DNA methylation and brain structure and function across the life course: A systematic review. (2020)
- Defining the Genetic, Genomic, Cellular, and Diagnostic Architectures of Psychiatric Disorders. (2019)
- Genome-wide association study reveals novel loci associated with body size and carcass yields in Pekin ducks. (2019)
- Epigenetics and depression . (2019)
- Psychiatric Genomics: An Update and an Agenda. (2018)
- CACNA1C: Association With Psychiatric Disorders, Behavior, and Neurogenesis. (2018)
- Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood. (2018)
- Assembly of functionally integrated human forebrain spheroids. (2017)
- The genomic landscape of balanced cytogenetic abnormalities associated with human congenital anomalies. (2017)
- Recent genetic findings in schizophrenia and their therapeutic relevance. (2015)
- Candidate gene-environment interaction research: reflections and recommendations. (2015)
- Genetics and genomics of psychiatric disease. (2015)
- The impact of environmental factors in severe psychiatric disorders. (2014)
- Altered gamma-aminobutyric acid type B receptor subunit 1 splicing in alcoholics. (2014)
- Early exposure to alcohol leads to permanent impairment of dendritic excitability in neocortical pyramidal neurons. (2012)
- Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned. (2012)
- CNVs: harbingers of a rare variant revolution in psychiatric genetics. (2012)
- A promoter polymorphism in the Per3 gene is associated with alcohol and stress response. (2012)
- High frequencies of de novo CNVs in bipolar disorder and schizophrenia. (2011)
- Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43. (2011)
- Genome-wide association study identifies five new schizophrenia loci. (2011)
- Low concentrations of alcohol inhibit BDNF-dependent GABAergic plasticity via L-type Ca2+ channel inhibition in developing CA3 hippocampal pyramidal neurons. (2010)
- Genome-wide association study of bipolar disorder in European American and African American individuals. (2009)
- Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. (2009)
- Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk. (2009)
- In utero cocaine-induced dysfunction of dopamine D1 receptor signaling and abnormal differentiation of cerebral cortical neurons. (2000)
- Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: evidence from positron emission tomography studies with [11C]WIN-35,428. (1998)
Merged raw entities (16)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| cacna1c | gene | 32 | 103 |
| cav1.2 | gene | 1 | 1 |
| alpha 1c subunit of the l-type voltage-gated calcium channel | gene | — | — |
| cacn1ac | gene | — | — |
| cacna1c38 | gene | — | — |
| calcium channel, voltage-dependent, l type, alpha 1c subunit | gene | — | — |
| calcium channel, voltage dependent, l type, α-1c subunit | gene | — | — |
| calcium channel, voltage-dependent, l type, α 1c subunit | gene | — | — |
| calcium voltage-gated channel subunit alpha1 c | gene | — | — |
| cav1.2 α subunit | gene | — | — |
| l-type calcium channel cacn1ac | gene | — | — |
| l-type voltage-gated ca2+ channel α1c | gene | — | — |
| timothy syndrome gene | gene | — | — |
| ts-cav1.2 | gene | — | — |
| voltage-dependent l-type calcium channel subunit alpha-1c | gene | — | — |
| α1c | gene | — | — |