HLA gene

Aliases

HLA genes, HLA types, MHC/HLA genes, human leukocyte antigen, human lymphocyte antigen

External links

NCBI Gene · Ensembl · GeneCards · UniProt

Related entities (10)

Mentioned in (60)

Papers in which this entity is mentioned.

• Tumour-wide RNA splicing aberrations generate actionable public neoantigens. (2025)
• Robust and accurate Bayesian inference of genome-wide genealogies for hundreds of genomes. (2025)
• Chromosomal instability as a driver of cancer progression. (2025)
• Functional analysis of cancer-associated germline risk variants. (2025)
• Splicing neoantigen discovery with SNAF reveals shared targets for cancer immunotherapy. (2024)
• Principles and methods for transferring polygenic risk scores across global populations. (2024)
• Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors. (2023)
• The Genetic Architecture of Obsessive-Compulsive Disorder: Contribution of Liability to OCD From Alleles Across the Frequency Spectrum. (2022)
• Most non-canonical proteins uniquely populate the proteome or immunopeptidome. (2021)
• Nanopore sequencing technology, bioinformatics and applications. (2021)
• Rapid genotype imputation from sequence with reference panels. (2021)
• Genotypes of informative loci from 1000 Genomes data allude evolution and mixing of human populations. (2021)
• Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity. (2021)
• Polygenic risk scores: from research tools to clinical instruments. (2020)
• MHCAttnNet: predicting MHC-peptide bindings for MHC alleles classes I and II using an attention-based deep neural model. (2020)
• Immuno-genomic landscape of osteosarcoma. (2020)
• Reciprocal monoallelic expression of ASAR lncRNA genes controls replication timing of human chromosome 6. (2020)
• Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype. (2019)
• Machine Learning-Enhanced T Cell Neoepitope Discovery for Immunotherapy Design. (2019)
• Sex differences in the genetic architecture of obsessive-compulsive disorder. (2019)
• HLA-VBSeq v2: improved HLA calling accuracy with full-length Japanese class-I panel. (2019)
• Rare variant phasing using paired tumor:normal sequence data. (2019)
• Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy. (2019)
• Genome-Informed Targeted Therapy for Osteosarcoma. (2019)
• HLA*LA-HLA typing from linearly projected graph alignments. (2019)
• Best practices for bioinformatic characterization of neoantigens for clinical utility. (2019)
• Circular DNA elements of chromosomal origin are common in healthy human somatic tissue. (2018)
• Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types. (2018)
• Immune diversity sheds light on missing variation in worldwide genetic diversity panels. (2018)
• The Immune Landscape of Cancer. (2018)
• Predicting T cell recognition of MHC class I restricted neoepitopes. (2018)
• Fast and accurate HLA typing from short-read next-generation sequence data with xHLA. (2017)
• Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution. (2017)
• The fractured landscape of RNA-seq alignment: The default in our STARs (2017)
• Fast and Accurate Genomic Analyses using Genome Graphs (2017)
• High-Accuracy HLA Type Inference from Whole-Genome Sequencing Data Using Population Reference Graphs. (2016)
• Detecting Genomic Signatures of Natural Selection with Principal Component Analysis: Application to the 1000 Genomes Data. (2016)
• Recent genetic findings in schizophrenia and their therapeutic relevance. (2015)
• The IPD and IMGT/HLA database: allele variant databases. (2015)
• HLAreporter: a tool for HLA typing from next generation sequencing data. (2015)
• Profiling tissue-resident T cell repertoires by RNA sequencing. (2015)
• HLA-VBSeq: accurate HLA typing at full resolution from whole-genome sequencing data. (2015)
• Transcriptome sequencing of a large human family identifies the impact of rare noncoding variants. (2014)
• Inference of high resolution HLA types using genome-wide RNA or DNA sequencing reads. (2014)
• OptiType: precision HLA typing from next-generation sequencing data. (2014)
• Heritability and genomics of gene expression in peripheral blood. (2014)
• Cancer genome landscapes. (2013)
• HLA typing from 1000 genomes whole genome and whole exome illumina data. (2013)
• Properties of MHC class I presented peptides that enhance immunogenicity. (2013)
• Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. (2012)
• Pathway analysis of genomic data: concepts, methods, and prospects for future development. (2012)
• Evolution and functional impact of rare coding variation from deep sequencing of human exomes. (2012)
• HLA typing from RNA-Seq sequence reads. (2012)
• Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. (2011)
• Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging. (2011)
• Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk. (2009)
• Common and rare variants in multifactorial susceptibility to common diseases. (2008)
• The HLA system: genetics, immunology, clinical testing, and clinical implications. (2007)
• Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. (2007)
• A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. (2006)

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