Sox2 gene
Evidence from:
primary |
all sources
Related entities (29)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| abstinence | interacts_with | Sox2 | 0.001 | 1 |
| BRG1 | interacts_with | Sox2 | — | 1 |
| forebrain | associated_with | Sox2 | — | 1 |
| Lipofectamine 2000 | associated_with | Sox2 | — | 1 |
| neurogenesis | associated_with | Sox2 | — | 1 |
| polybrene | associated_with | Sox2 | — | 1 |
| Sendai virus | regulates | Sox2 | — | 1 |
| Sox2 | expressed_in | astroglia | — | 1 |
| Sox2 | expressed_in | brain | — | 1 |
| Sox2 | associated_with | BRG1 | — | 1 |
| Sox2 | regulates | Cox6a1 | — | 1 |
| Sox2 | expressed_in | dentate gyrus | — | 1 |
| Sox2 | expressed_in | hiPSCs | — | 1 |
| Sox2 | associated_with | HOPX | — | 1 |
| Sox2 | expressed_in | iPSC lines | — | 1 |
| Sox2 | regulates | MAP2K5 | — | 1 |
| Sox2 | expressed_in | neocortex | — | 1 |
| Sox2 | expressed_in | neural progenitors | — | 1 |
| Sox2 | regulates | neural stem cells | — | 1 |
| Sox2 | expressed_in | neural stem cells | — | 2 |
| Sox2 | biomarker_for | neural stem cells | — | 1 |
| Sox2 | expressed_in | NPCs | — | 2 |
| Sox2 | associated_with | OLIG1 | — | 1 |
| Sox2 | associated_with | Pax6 | — | 1 |
| Sox2 | associated_with | PDGFRA | — | 1 |
| Sox2 | expressed_in | SVZ | — | 1 |
| Sox2 | associated_with | TBR2 | — | 1 |
| Sox2 | associated_with | VIM | — | 1 |
| Valproic acid | associated_with | Sox2 | — | 1 |
Mentioned in (71)
Papers in which this entity is mentioned.
- LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development. (2025)
- Identifying Spatial Co-occurrence in Healthy and InflAmed tissues (ISCHIA). (2024)
- Impact of alcohol exposure on neural development and network formation in human cortical organoids. (2023)
- RNA splicing dysregulation and the hallmarks of cancer. (2023)
- GATA4/5/6 family transcription factors are conserved determinants of cardiac versus pharyngeal mesoderm fate. (2022)
- Massively parallel reporter perturbation assays uncover temporal regulatory architecture during neural differentiation. (2022)
- Spatially resolved whole transcriptome profiling in human and mouse tissue using Digital Spatial Profiling. (2022)
- Inferring gene expression from cell-free DNA fragmentation profiles. (2022)
- Evaluating the transcriptional fidelity of cancer models. (2021)
- Prenatal alcohol exposure disrupts Sonic hedgehog pathway and primary cilia genes in the mouse neural tube. (2021)
- Inference and analysis of cell-cell communication using CellChat. (2021)
- Pan-cancer analysis of whole genomes. (2020)
- Tead transcription factors differentially regulate cortical development. (2020)
- Folding Keratin Gene Clusters during Skin Regional Specification. (2020)
- Murine Models for the Study of Fetal Alcohol Spectrum Disorders: An Overview. (2020)
- Modification of stem cell states by alcohol and acetaldehyde. (2020)
- Cannabinoids Exacerbate Alcohol Teratogenesis by a CB1-Hedgehog Interaction. (2019)
- Super-enhancers: critical roles and therapeutic targets in hematologic malignancies. (2019)
- Comparative RNA-seq analysis aids in diagnosis of a rare pediatric tumor. (2019)
- De Novo Missense Variants in FBXW11 Cause Diverse Developmental Phenotypes Including Brain, Eye, and Digit Anomalies. (2019)
- HOCOMOCO: towards a complete collection of transcription factor binding models for human and mouse via large-scale ChIP-Seq analysis. (2018)
- The Human Transcription Factors. (2018)
- Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. (2018)
- ApoE Regulates the Development of Adult Newborn Hippocampal Neurons. (2018)
- Diving into the world of alcohol teratogenesis: a review of zebrafish models of fetal alcohol spectrum disorder. (2018)
- Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors. (2017)
- Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain. (2017)
- Disconnect between alcohol-induced alterations in chromatin structure and gene transcription in a mouse embryonic stem cell model of exposure. (2017)
- Early pathogenic event of Alzheimer's disease documented in iPSCs from patients with PSEN1 mutations. (2017)
- Single-Cell Profiling of an In Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation. (2017)
- Prenatal ethanol exposure in mice phenocopies Cdon mutation by impeding Shh function in the etiology of optic nerve hypoplasia. (2017)
- Musculocontractural Ehlers-Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin. (2016)
- Three Dimensional Human Neuro-Spheroid Model of Alzheimer's Disease Based on Differentiated Induced Pluripotent Stem Cells. (2016)
- Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes. (2016)
- Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. (2016)
- Dose-dependent alcohol-induced alterations in chromatin structure persist beyond the window of exposure and correlate with fetal alcohol syndrome birth defects. (2015)
- GABRA2 Alcohol Dependence Risk Allele is Associated with Reduced Expression of Chromosome 4p12 GABAA Subunit Genes in Human Neural Cultures. (2015)
- Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells. (2015)
- Spontaneous ATM Gene Reversion in A-T iPSC to Produce an Isogenic Cell Line. (2015)
- Unraveling the clonal hierarchy of somatic genomic aberrations. (2014)
- The role of BAF (mSWI/SNF) complexes in mammalian neural development. (2014)
- Induced neuronal reprogramming. (2014)
- Gene expression signatures affected by alcohol-induced DNA methylomic deregulation in human embryonic stem cells. (2014)
- Roles of heat shock factor 1 in neuronal response to fetal environmental risks and its relevance to brain disorders. (2014)
- Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis. (2014)
- Cleft Palate in a Mouse Model of SOX2 Haploinsufficiency. (2014)
- EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma. (2014)
- Modeling hippocampal neurogenesis using human pluripotent stem cells. (2014)
- Identification of cell-specific patterns of reference gene stability in quantitative reverse-transcriptase polymerase chain reaction studies of embryonic, placental and neural stem models of prenatal ethanol exposure. (2013)
- The sox family of transcription factors: versatile regulators of stem and progenitor cell fate. (2013)
- DNA methylation program in developing hippocampus and its alteration by alcohol. (2013)
- Alcohol-induced epigenetic alterations to developmentally crucial genes regulating neural stemness and differentiation. (2013)
- Cannabinoid receptor 1 signaling in embryo neurodevelopment. (2012)
- Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives. (2012)
- SOX2 hypomorphism disrupts development of the prechordal floor and optic cup. (2012)
- Pilot study of iPS-derived neural cells to examine biologic effects of alcohol on human neurons in vitro. (2012)
- Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs. (2012)
- Emerging role of non-coding RNA in neural plasticity, cognitive function, and neuropsychiatric disorders. (2012)
- GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers. (2011)
- Functional consequences of developmentally regulated alternative splicing. (2011)
- Molecular mechanisms of long noncoding RNAs. (2011)
- Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord. (2011)
- Long-term suppression of forebrain neurogenesis and loss of neuronal progenitor cells following prolonged alcohol dependence in rats. (2010)
- Novel SOX2 mutations and genotype-phenotype correlation in anophthalmia and microphthalmia. (2009)
- The embryonic preoptic area is a novel source of cortical GABAergic interneurons. (2009)
- Identification of novel mutations and sequence variants in the SOX2 and CHX10 genes in patients with anophthalmia/microphthalmia. (2008)
- Familial recurrence of SOX2 anophthalmia syndrome: phenotypically normal mother with two affected daughters. (2008)
- Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. (2007)
- Mutations within Sox2/SOX2 are associated with abnormalities in the hypothalamo-pituitary-gonadal axis in mice and humans. (2006)
- SOX2 is a dose-dependent regulator of retinal neural progenitor competence. (2006)
- Origin of oligodendrocytes in the subventricular zone of the adult brain. (2006)
Merged raw entities (5)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| sox2 | gene | 71 | 364 |
| sex-determining region y-box 2 | gene | — | — |
| sry-box 2 | gene | — | — |
| sry-box transcription factor 2 | gene | — | — |
| sry-related high-mobility group box 2 | gene | — | — |