rs1051730 variant

Aliases: 15q25.1 SNP rs1051730, CHRNA3 (Ex5+268), CHRNA3-rs1051730, CHRNA3-rs1051730[A], CHRNA3-rs1051730[A] allele, SNP rs1051730, chr15q25.1 SNP rs1051730, chr15q25.1 rs1051730, rs1051730 SNP, rs1051730[A], variant rs1051730
External links: dbSNP · ClinVar

Evidence from: primary | all sources

Related entities (63)

Subject	Relation	Object	p-value	Evidence
maternal smoking	interacts_with	rs1051730	—	1
maternal smoking	associated_with	rs1051730	—	1
nicotine	associated_with	rs1051730	—	1
rs10502172	interacts_with	rs1051730	0.53	1
rs1051730	associated_with	6-month abstinence	—	1
rs1051730	associated_with	abstinence	0.005	1
rs1051730	biomarker_for	abstinence	—	1
rs1051730	protective_against	abstinence	0.007	1
rs1051730	risk_factor_for	abstinence	0.016	1
rs1051730	regulates	abstinence	—	1
rs1051730	associated_with	adolescents	—	1
rs1051730	associated_with	bipolar disorder	—	1
rs1051730	risk_factor_for	birth weight	0.07	1
rs1051730	interacts_with	Chrna3	—	1
rs1051730	associated_with	Chrna3	1.1e-05	4
rs1051730	regulates	CHRNA5	5.11e-06	1
rs1051730	associated_with	CHRNA5	—	3
rs1051730	interacts_with	CHRNA5-CHRNA3-CHRNB4 cluster	—	1
rs1051730	associated_with	Chrnb4	—	4
rs1051730	associated_with	cigarettes	—	1
rs1051730	associated_with	cognition	—	1
rs1051730	associated_with	CPD	5e-32	2
rs1051730	risk_factor_for	CPD	0.001	1
rs1051730	associated_with	FTND	—	2
rs1051730	risk_factor_for	FTND	—	1
rs1051730	associated_with	FTND score	0.016	2
rs1051730	risk_factor_for	FTND score	0.016	1
rs1051730	associated_with	heavy drinking	—	1
rs1051730	risk_factor_for	heavy smoking	0.0003	2
rs1051730	associated_with	heavy smoking	—	1
rs1051730	associated_with	light smokers	—	1
rs1051730	associated_with	lung cancer	—	1
rs1051730	risk_factor_for	lung cancer	1e-08	3
rs1051730	risk_factor_for	maternal smoking	—	1
rs1051730	associated_with	maternal smoking	—	1
rs1051730	associated_with	nicotine	6e-20	5
rs1051730	risk_factor_for	nicotine	—	4
rs1051730	interacts_with	NRT	—	1
rs1051730	associated_with	number of cigarettes smoked per day	—	1
rs1051730	risk_factor_for	number of cigarettes smoked per day	0	1
rs1051730	risk_factor_for	occasional smokers	—	1
rs1051730	associated_with	quitting success	—	1
rs1051730	associated_with	rs10502172	—	1
rs1051730	interacts_with	rs16969968	—	1
rs1051730	associated_with	schizophrenia	—	1
rs1051730	risk_factor_for	smoking	—	1
rs1051730	associated_with	smoking	—	1
rs1051730	associated_with	smoking abstinence	—	1
rs1051730	associated_with	smoking behavior	—	1
rs1051730	risk_factor_for	smoking behavior	—	1
rs1051730	associated_with	smoking behaviors	—	1
rs1051730	associated_with	smoking behaviour	—	1
rs1051730	associated_with	smoking heaviness	—	1
rs1051730	risk_factor_for	smoking persistence	—	1
rs1051730	risk_factor_for	smoking quantity	—	2
rs1051730	associated_with	smoking quantity	6e-20	1
rs1051730	risk_factor_for	smoking severity	—	1
rs1051730	risk_factor_for	vascular disease	—	1
rs1051730	associated_with	white participants	—	1
rs1051730	associated_with	working memory	—	1
rs16969968	interacts_with	rs1051730	—	1
rs16969968	associated_with	rs1051730	—	2
rs578776	interacts_with	rs1051730	—	1

Mentioned in (9)

Papers in which this entity is mentioned.

Human Genetics of Addiction: New Insights and Future Directions. (2018)
Genetic variability in the regulation of gene expression in ten regions of the human brain. (2014)
Nicotinic acetylcholine receptor variation and response to smoking cessation therapies. (2013)
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. (2012)
TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood. (2011)
Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence. (2011)
Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence. (2009)
A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy. (2009)
Genome-wide and candidate gene association study of cigarette smoking behaviors. (2009)

Merged raw entities (12)

All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.

Raw name	Type	Papers	Mentions
rs1051730	variant	9	56
chrna3-rs1051730	variant	1	4
chrna3-rs1051730[a]	variant	1	2
15q25.1 snp rs1051730	variant	—	—
chr15q25.1 rs1051730	variant	—	—
chr15q25.1 snp rs1051730	variant	—	—
chrna3 (ex5+268)	variant	—	—
chrna3-rs1051730[a] allele	variant	—	—
rs1051730[a]	variant	—	—
rs1051730 snp	variant	—	—
snp rs1051730	variant	—	—
variant rs1051730	variant	—	—