smoking behavior phenotype

Aliases: cigarette smoking, cigarettes per day, cigarettes smoked per day, current smokers, former smokers, initiation of smoking, nicotine use, propensity to smoke, smoking, smoking behavior, smoking behaviors, smoking to offset serotonin deficit, tobacco use

Evidence from: primary | all sources

Related entities (63)

Subject	Relation	Object	p-value	Evidence
Alcohol Use	associated_with	smoking behavior	—	1
candidate genes	associated_with	smoking behavior	—	1
Chrna3	associated_with	smoking behavior	1e-06	2
Chrna3	risk_factor_for	smoking behavior	—	1
Chrna4	associated_with	smoking behavior	—	1
Chrna4	risk_factor_for	smoking behavior	—	1
CHRNA5	associated_with	smoking behavior	1e-06	2
CHRNA5	risk_factor_for	smoking behavior	—	1
CHRNA5-CHRNA3-CHRNB4 cluster	associated_with	smoking behavior	—	1
Chrna6	associated_with	smoking behavior	—	1
Chrnb3	associated_with	smoking behavior	—	1
Chrnb4	associated_with	smoking behavior	—	1
Chrnb4	risk_factor_for	smoking behavior	—	1
cigarettes	associated_with	smoking behavior	—	1
Collaborative Study on the Genetics of Alcoholism (COGA)	associated_with	smoking behavior	—	1
common variants	associated_with	smoking behavior	—	1
common variants	risk_factor_for	smoking behavior	—	1
cotinine	biomarker_for	smoking behavior	—	1
CPD	biomarker_for	smoking behavior	—	1
craving	risk_factor_for	smoking behavior	—	1
CTNNA3	associated_with	smoking behavior	—	1
CYP2A6	associated_with	smoking behavior	—	1
DAT1 VNTR	associated_with	smoking behavior	—	1
Europeans	associated_with	smoking behavior	—	1
Fagerström Test for Nicotine Dependence	associated_with	smoking behavior	—	1
FTO	associated_with	smoking behavior	—	1
Koreans	associated_with	smoking behavior	—	1
major depressive disorder	associated_with	smoking behavior	—	1
negative affect	risk_factor_for	smoking behavior	—	1
negative mood	risk_factor_for	smoking behavior	—	1
nicotine	associated_with	smoking behavior	—	1
nicotine clearance	regulates	smoking behavior	—	1
nicotine metabolism	risk_factor_for	smoking behavior	—	1
nicotine withdrawal	risk_factor_for	smoking behavior	—	1
novelty seeking	risk_factor_for	smoking behavior	—	1
Peer influences	risk_factor_for	smoking behavior	—	1
peers	risk_factor_for	smoking behavior	—	1
Psychosocial factors	risk_factor_for	smoking behavior	—	1
RORB	associated_with	smoking behavior	—	1
rs1044394	associated_with	smoking behavior	—	1
rs1044396	associated_with	smoking behavior	—	1
rs10502172	risk_factor_for	smoking behavior	—	1
rs1051730	risk_factor_for	smoking behavior	—	1
rs1051730	associated_with	smoking behavior	—	1
rs16969968	associated_with	smoking behavior	—	2
rs16969968	risk_factor_for	smoking behavior	—	1
rs2236196	risk_factor_for	smoking behavior	—	1
rs2236196	associated_with	smoking behavior	—	1
SLC6A4	risk_factor_for	smoking behavior	—	1
SLC6A4	associated_with	smoking behavior	—	1
SLCO3A1	associated_with	smoking behavior	—	1
smoking behavior	risk_factor_for	adolescent substance use	—	1
smoking behavior	associated_with	alcohol sensitivity	—	1
smoking behavior	associated_with	Collaborative Study on the Genetics of Alcoholism (COGA)	—	1
smoking behavior	associated_with	CPD	—	1
smoking behavior	protective_against	craving	—	1
smoking behavior	risk_factor_for	lung cancer	—	1
smoking behavior	associated_with	nicotine	—	1
smoking behavior	risk_factor_for	smoking cessation	—	1
smoking behavior	associated_with	tobacco use	—	1
SNP	associated_with	smoking behavior	—	1
SRE	associated_with	smoking behavior	—	1
tobacco use	associated_with	smoking behavior	—	1

Mentioned in (36)

Papers in which this entity is mentioned.

Trajectories of genetic risk across dimensions of alcohol use behaviors. (2025)
An overview of DNA methylation-derived trait score methods and applications. (2023)
Genetic association study of childhood aggression across raters, instruments, and age. (2021)
Psychiatric Genomics: An Update and an Agenda. (2018)
Meta-Analysis of Genetic Influences on Initial Alcohol Sensitivity. (2018)
A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism. (2015)
Time to First Morning Cigarette and Risk of Chronic Obstructive Pulmonary Disease: Smokers in the PLCO Cancer Screening Trial. (2015)
Is the gene-environment interaction paradigm relevant to genome-wide studies? The case of education and body mass index. (2014)
Genetic variability in the regulation of gene expression in ten regions of the human brain. (2014)
Polygenic risk scores for smoking: predictors for alcohol and cannabis use? (2014)
Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking. (2013)
The co-occurring use and misuse of cannabis and tobacco: a review. (2012)
The genetic basis of addictive disorders. (2012)
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. (2012)
Association of CHRNA4 polymorphisms with smoking behavior in two populations. (2011)
An Interdisciplinary Approach to Studying Gene-Environment Interactions: From Twin Studies to Gene Identification and Back. (2011)
TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood. (2011)
Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence. (2011)
Genetic polymorphisms in 15q25 and 19q13 loci, cotinine levels, and risk of lung cancer in EPIC. (2011)
The investigation into CYP2E1 in relation to the level of response to alcohol through a combination of linkage and association analysis. (2011)
A population-based twin study of the genetic and environmental relationship of major depression, regular tobacco use and nicotine dependence. (2011)
Beyond Homophily: A Decade of Advances in Understanding Peer Influence Processes. (2011)
The serotonin transporter gene and startle response during nicotine deprivation. (2011)
Genetics of psychiatric disorders methods: molecular approaches. (2010)
The Moderating Effects of Pubertal Timing on the Longitudinal Associations Between Parent-Child Relationship Quality and Adolescent Substance Use. (2010)
Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25. (2010)
Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans. (2010)
Nicotine withdrawal sensitivity, linkage to chr6q26, and association of OPRM1 SNPs in the SMOking in FAMilies (SMOFAM) sample. (2009)
Prenatal cocaine exposure alters emotional arousal regulation and its effects on working memory. (2009)
Genome-wide and candidate gene association study of cigarette smoking behaviors. (2009)
Real-time craving and mood assessments before and after smoking. (2008)
Rate of nicotine metabolism and withdrawal symptoms in adolescent light smokers. (2008)
Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking. (2008)
A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population. (2003)
Sociocultural influences on smoking and drinking. (2000)
The sociodemographic predictors of smoking cessation among pregnant women in Canada. (1999)

Merged raw entities (2)

All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.

Raw name	Type	Papers	Mentions
smoking behavior	phenotype	36	85
smoking to offset serotonin deficit	phenotype	—	—