H3K27me3 drug
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Related entities (8)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| BAF | regulates | H3K27me3 | — | 1 |
| BRG1 | regulates | H3K27me3 | — | 1 |
| chromatin states | associated_with | H3K27me3 | — | 1 |
| citalopram | regulates | H3K27me3 | — | 1 |
| H3K27me3 | associated_with | H3K27ac | — | 1 |
| H3K27me3 | associated_with | H3K9me3 | — | 1 |
| H3K27me3 | associated_with | pluripotent cells | — | 1 |
| PRC2 | regulates | H3K27me3 | — | 1 |
Mentioned in (61)
Papers in which this entity is mentioned.
- Advancing regulatory variant effect prediction with AlphaGenome. (2026)
- Tracing the evolution of single-cell 3D genomes in Kras-driven cancers. (2025)
- Nucleotide Transformer: building and evaluating robust foundation models for human genomics. (2025)
- Transcription start sites experience a high influx of heritable variants fueled by early development. (2025)
- Transient loss of Polycomb components induces an epigenetic cancer fate. (2024)
- A DNA methylation atlas of normal human cell types. (2023)
- Massively parallel reporter perturbation assays uncover temporal regulatory architecture during neural differentiation. (2022)
- Nanopore sequencing technology, bioinformatics and applications. (2021)
- Simultaneous epigenetic perturbation and genome imaging reveal distinct roles of H3K9me3 in chromatin architecture and transcription. (2020)
- Neonatal Alcohol Exposure in Mice Induces Select Differentiation- and Apoptosis-Related Chromatin Changes Both Independent of and Dependent on Sex. (2020)
- Murine Models for the Study of Fetal Alcohol Spectrum Disorders: An Overview. (2020)
- Genetic compensation triggered by mutant mRNA degradation. (2019)
- Super-enhancers: critical roles and therapeutic targets in hematologic malignancies. (2019)
- Global DNA Methylation and Histone Posttranslational Modifications in Human and Nonhuman Primate Brain in Association with Prenatal Alcohol Exposure. (2019)
- Epigenetics and depression . (2019)
- Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility. (2018)
- Epigenetic mechanisms in alcohol- and adversity-induced developmental origins of neurobehavioral functioning. (2018)
- Neuroepigenetics and addiction. (2018)
- PI3K Signaling in Neurons: A Central Node for the Control of Multiple Functions. (2018)
- Accurate Recycling of Parental Histones Reproduces the Histone Modification Landscape during DNA Replication. (2018)
- Constrained release of lamina-associated enhancers and genes from the nuclear envelope during T-cell activation facilitates their association in chromosome compartments. (2017)
- Universal Patterns of Selection in Cancer and Somatic Tissues. (2017)
- Network analysis identifies chromosome intermingling regions as regulatory hotspots for transcription. (2017)
- Orthotopic patient-derived xenografts of paediatric solid tumours. (2017)
- DNA replication timing during development anticipates transcriptional programs and parallels enhancer activation. (2017)
- Disconnect between alcohol-induced alterations in chromatin structure and gene transcription in a mouse embryonic stem cell model of exposure. (2017)
- Nuclear organization and 3D chromatin architecture in cognition and neuropsychiatric disorders. (2016)
- Cause and Consequence of Tethering a SubTAD to Different Nuclear Compartments. (2016)
- The placenta and neurodevelopment: sex differences in prenatal vulnerability. (2016)
- Alteration of Gene Expression, DNA Methylation, and Histone Methylation in Free Radical Scavenging Networks in Adult Mouse Hippocampus following Fetal Alcohol Exposure. (2016)
- Tissue-Specific Gene Repositioning by Muscle Nuclear Membrane Proteins Enhances Repression of Critical Developmental Genes during Myogenesis. (2016)
- Two distinct modes for propagation of histone PTMs across the cell cycle. (2015)
- Dose-dependent alcohol-induced alterations in chromatin structure persist beyond the window of exposure and correlate with fetal alcohol syndrome birth defects. (2015)
- Mechanisms of retinoic acid signalling and its roles in organ and limb development. (2015)
- Developmental exposure to 50 parts-per-billion arsenic influences histone modifications and associated epigenetic machinery in a region- and sex-specific manner in the adult mouse brain. (2015)
- Epigenomics and the structure of the living genome. (2015)
- Prenatal ethanol exposure alters adult hippocampal VGLUT2 expression with concomitant changes in promoter DNA methylation, H3K4 trimethylation and miR-467b-5p levels. (2015)
- An atlas of active enhancers across human cell types and tissues. (2014)
- The role of BAF (mSWI/SNF) complexes in mammalian neural development. (2014)
- Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation. (2014)
- Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations. (2014)
- Long-term genomic and epigenomic dysregulation as a consequence of prenatal alcohol exposure: a model for fetal alcohol spectrum disorders. (2014)
- EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma. (2014)
- RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts. (2013)
- The sox family of transcription factors: versatile regulators of stem and progenitor cell fate. (2013)
- In utero alcohol exposure, epigenetic changes, and their consequences. (2013)
- Alcohol-induced epigenetic alterations to developmentally crucial genes regulating neural stemness and differentiation. (2013)
- Landscape of transcription in human cells. (2012)
- Novel mutations target distinct subgroups of medulloblastoma. (2012)
- An integrated encyclopedia of DNA elements in the human genome. (2012)
- Regulation of chromatin by histone modifications. (2011)
- Extensive epigenetic reprogramming in human somatic tissues between fetus and adult. (2011)
- CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing. (2011)
- Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation. (2010)
- Conserved role of intragenic DNA methylation in regulating alternative promoters. (2010)
- A novel and universal method for microRNA RT-qPCR data normalization. (2009)
- Computation for ChIP-seq and RNA-seq studies. (2009)
- Model-based analysis of ChIP-Seq (MACS). (2008)
- Model-based analysis of ChIP-Seq (MACS). (2008)
- Model-based analysis of ChIP-Seq (MACS). (2008)
- Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. (2007)
Merged raw entities (3)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| h3k27me3 | drug | 61 | 203 |
| histone h3 lysine-27 trimethylation | drug | — | — |
| repressive histone mark h3k27me3 | drug | — | — |